Endocrinologia Diabetes Y Nutricion最新文献

{"title":"Beyond vectorial bioelectrical impedance: Assessing body composition changes with novel electrical parameters in obese osteoarthritis patients on a meal-replacement diet","authors":"José-Joaquín Alfaro-Martínez ,&nbsp;David Primo-Martín ,&nbsp;César Gonzalvo-Díaz ,&nbsp;Olatz Izaola-Jauregui ,&nbsp;Marina Jara-Vidal ,&nbsp;Lourdes García-Blasco ,&nbsp;Beatriz Ramos-Bachiller ,&nbsp;Diego Bellido-Guerrero ,&nbsp;Daniel A. De Luis-Román ,&nbsp;Juan José López-Gómez","doi":"10.1016/j.endien.2025.501644","DOIUrl":"10.1016/j.endien.2025.501644","url":null,"abstract":"<div><h3>Background</h3><div>Rapid weight loss with restricted diets can cause muscle mass decline. The aim of this work is to evaluate a new method for representing the raw electrical values obtained in the bioelectrical impedance analysis (BIA) in patients with obesity and osteoarthritis undergoing a meal-replacement diet.</div></div><div><h3>Methods</h3><div>We conducted a 1-group intervention study with meal-replacement diet for 3 months in patients with osteoarthritis prior to orthopedic surgery. Anthropometry and BIA was registered at baseline (B) and 3 months (3M) after the intervention. We have calculated traditional estimations of body composition over the raw electrical parameters of BIA parameters and a new bioelectrical impedance vector analysis (BIVA) based method to detect nutrition (NP), hydration (HP) and fat (FP) parameters without estimation.</div></div><div><h3>Results</h3><div>A total of 272 patients (23.16% men; 76.84% women) were analyzed. There was a correlation between NP and body composition estimates (body cell mass [BCM] standardized by height (BCM/h): men: 0.96; <em>p</em> <!-->&lt;<!--> <!-->0.01; women: 0.88; <em>p</em> <!-->&lt;<!--> <!-->0.01). The correlation coefficient between HP and estimated total body water was 0.769 for men and 0.63 for women (<em>p</em> <!-->&lt;<!--> <!-->0.01 in both cases). The correlation coefficient between FP and estimated fat mass (FM) standardized by height was 0.83 for men and 0.89 for women (<em>p</em> <!-->&lt;<!--> <!-->0.01). There was a significant decrease in body weight (<em>B</em>: 99.33(15.0)<!--> <!-->kg; 3M: 92.03(16.0)<!--> <!-->kg; <em>p</em> <!-->&lt;<!--> <!-->0.01); and FM (<em>B</em>: 49.93(6.67)<!--> <!-->kg; 3M: 44.22(9.08)<!--> <!-->kg). There was no difference in BCM and fat free mass. In new parameters a decrease in NP (<em>B</em>: +0.50(0.31); 3M: +0.42(0.42); <em>p</em> <!-->=<!--> <!-->0.03) and FP (<em>B</em>: +0.49(0.17) was reported; 3M: +0.38(0.16); <em>p</em> <!-->&lt;<!--> <!-->0.01), although there was no difference in HP.</div></div><div><h3>Conclusions</h3><div>The new interpretation of BIVA as NP and HP have a high correlation with the body composition parameters estimated by regression models, and they report changes in body composition after a partial meal-replacement diet such as regression equations.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 1","pages":"Article 501644"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146001833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radioactive iodine-induced esophagitis: A rare complication","authors":"Ignacio Jiménez Hernando ,&nbsp;Irene Bretón Lesmes ,&nbsp;Arantxa Díaz Gómez ,&nbsp;Miguel Sebastián Casallas Cepeda ,&nbsp;Santiago Salcedo Cortés","doi":"10.1016/j.endien.2025.501656","DOIUrl":"10.1016/j.endien.2025.501656","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 1","pages":"Article 501656"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146001818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin K in home parenteral nutrition: Is it really necessary?","authors":"Estrella Diego ,&nbsp;María del Carmen Farnández ,&nbsp;Beatriz de León ,&nbsp;Andoni Monzón ,&nbsp;Leire Isasa ,&nbsp;Beatriz Sordo ,&nbsp;Nuria Valdés","doi":"10.1016/j.endien.2025.501655","DOIUrl":"10.1016/j.endien.2025.501655","url":null,"abstract":"<div><h3>Introduction</h3><div>Multivitamin preparations with added vitamin K in parenteral nutrition (PN) ensure the coverage of this micronutrient in all adults, as indicated by the latest ESPEN clinical practice guidelines on micronutrients.</div></div><div><h3>Objectives</h3><div>To monitor vitamin K levels after adding this multivitamin with vitamin K in patients requiring home parenteral nutrition (HPN) at <em>Hospital Universitario Cruces</em> (Bilbao, Basque County, Spain) from 2021 to 2022.</div></div><div><h3>Materials and methods</h3><div>We analyzed vitamin K levels were collected 6 months into therapy with the multivitamin containing vitamin K in home parenteral nutrition.</div></div><div><h3>Results</h3><div>At our centre, a total of 8 patients required home parenteral nutrition due to intestinal failure type III, 60% of whom were men, with a mean age of 58<!--> <!-->±<!--> <!-->13 years. The cause of intestinal failure was short bowel syndrome (50%), intestinal mucosal disease (38%), and intestinal dysmotility (12%). After adding the multivitamin with vitamin K, 80% (6/8) of patients exhibited elevated vitamin K levels, with a mean of 4.4<!--> <!-->μl/L.</div></div><div><h3>Conclusions</h3><div>After observing vitamin K levels above the upper limit of normal, we reached consensus with the Pharmacy Service to discontinue this multivitamin and restart conventional multivitamin. After this initiative, the vitamin K levels of our patients normalized.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 1","pages":"Article 501655"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146001834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in pituitary tumors following the 2022 WHO classification","authors":"Ignacio Ruz-Caracuel","doi":"10.1016/j.endien.2026.501747","DOIUrl":"10.1016/j.endien.2026.501747","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 1","pages":"Article 501747"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146001832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute pancreatitis in an infant, a rare diagnosis","authors":"Fátima Pareja Marín,&nbsp;María Pilar Valverde Viu,&nbsp;Sara Vicent Martí,&nbsp;Violeta Martí Enrique","doi":"10.1016/j.endien.2025.501660","DOIUrl":"10.1016/j.endien.2025.501660","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 1","pages":"Article 501660"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145641021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ovarian metastasis in a young woman with follicular thyroid carcinoma: A differential diagnosis with struma ovarii.","authors":"Dolores Tejedo-Flors, Thalía Argüello-Gordillo, Elena Argente-Martínez, Beatriz López-Muñoz, Pedro López-Mondéjar","doi":"10.1016/j.endien.2025.501676","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501676","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501676"},"PeriodicalIF":1.8,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145758003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Second edition of the \"do not do\" recommendations from the Spanish Society of Endocrinology and Nutrition (SEEN).","authors":"Juan José Díez, Manuel Gargallo Fernández, José Antonio Gimeno Orna, Elena González Arnaiz, Isabel Huguet Moreno, Sílvia Martínez Couselo, María Miguélez González, María Julia Ocón, Gilberto Pérez López, Francisco Pita Gutiérrez, Jordi Luis Reverter Calatayud, Cristina Tejera Pérez, Eulàlia Urgell Rull, Alberto Fernández","doi":"10.1016/j.endien.2025.501687","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501687","url":null,"abstract":"<p><p>Low-value clinical practices - defined as diagnostic or therapeutic interventions that provide limited clinical benefit and may be associated with unnecessary risks or costs - remain common in endocrinology and nutrition. The Spanish Society of Endocrinology and Nutrition (SEEN) presents this second edition as an updated set of recommendations on \"what not to do\" in clinical practice, developed by its sections and working groups. The methodological process included the selection of relevant topics, systematic literature review, and multidisciplinary consensus. Key areas addressed include diabetes, obesity, nutrition, gonads, lipids, laboratory, mineral metabolism, and imaging, identifying low-value interventions and offering alternatives based on the best available evidence. The implementation of these recommendations aims to optimize care quality, reduce risks, and contribute to the sustainability of the healthcare system.</p>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501687"},"PeriodicalIF":1.8,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145758058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, incidence, and occupational risk markers of dyslipidemia in Peruvian workers.","authors":"Jhosmer Ballena-Caicedo, Fiorella E Zuzunaga-Montoya, Juan Carlos Bustamante-Rodríguez, Nataly Mayely Sanchez-Tamay, Luisa Erika Milagros Vásquez-Romero, Joan A Loayza-Castro, Carmen Inés Gutierrez De Carrillo, Víctor Juan Vera-Ponce","doi":"10.1016/j.endien.2025.501672","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501672","url":null,"abstract":"<p><strong>Introduction: </strong>Dyslipidemias are a significant risk factor for cardiovascular diseases. In Peru, nutritional transition and lifestyle changes may be contributing to an increase in the incidence of these metabolic disorders, particularly among the working population.</p><p><strong>Objective: </strong>To determine the incidence of dyslipidemias and evaluate associated occupational factors in Peruvian workers.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted using electronic medical records from 4,200 workers attending an occupational health clinic between 2013 and 2022. Incidence rates of hypertriglyceridemia, hypercholesterolemia, and combined dyslipidemia were calculated. Specific occupational factors (type of work, sitting time, and night shift work) were analyzed using Cox regression models adjusted for age (with splines) and sex.</p><p><strong>Results: </strong>The incidence of hypercholesterolemia (87.22 cases per 1,000 person-years; 95% CI: 79.99-94.45) was significantly higher than that of hypertriglyceridemia (65.71 cases per 1,000 person-years; 95% CI: 59.71-71.72). Combined dyslipidemia showed an incidence of 48.28 cases per 1,000 person-years (95% CI: 43.60-52.97). Workers in social services had a higher risk of developing dyslipidemias (aHR: 1.78; 95% CI: 1.27-2.49) compared to office workers. Prolonged sitting time (>4 h) was significantly associated with an increased risk of hypertriglyceridemia (aHR: 1.28; 95% CI: 1.05-1.56) and combined dyslipidemia (aHR: 1.42; 95% CI: 1.15-1.76).</p><p><strong>Conclusions: </strong>The high incidence of dyslipidemias-particularly hypercholesterolemia-may reflect the increasing consumption of ultra-processed foods and the ongoing nutritional transition in the Peruvian population. Occupational factors play a crucial role in the development of these metabolic disorders, highlighting the need for specific preventive strategies in the workplace.</p>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501672"},"PeriodicalIF":1.8,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Familial hypogonadotropic hypogonadism: The convergence of two genetic defects.","authors":"Luis Muñoz Arenas, Mercedes Senent Capote, Javier Olmedo Pérez-Montaut, Antonio Ballesteros Martín-Portugués, Esteban Sánchez-Toscano, Maria Gloria Baena-Nieto","doi":"10.1016/j.endien.2025.501675","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501675","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501675"},"PeriodicalIF":1.8,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Executive summary of the consensus document for the management of severe Cushing's syndrome: Consensus document of the Neuroendocrinology Focus Group of the Spanish Society of Endocrinology and Nutrition (SEEN)","authors":"Marta Araujo-Castro ,&nbsp;Rogelio García-Centeno ,&nbsp;Javier Aller ,&nbsp;Mónica Marazuela ,&nbsp;Alfonso Soto ,&nbsp;María Ángeles Gálvez ,&nbsp;Rosa Cámara ,&nbsp;Elena Valassi ,&nbsp;Ignacio Bernabeu ,&nbsp;Rocío Villar-Taibo ,&nbsp;Felicia A. Hanzu","doi":"10.1016/j.endien.2025.501654","DOIUrl":"10.1016/j.endien.2025.501654","url":null,"abstract":"<div><div>Severe Cushing's syndrome (SCS) is usually defined as a CS with urinary free cortisol (UFC) levels above five times the upper limit of normal or associated with severe complications of hypercortisolism. Combination therapy with ketoconazole and metyrapone is a useful option for these patients. Osilodrostat is the most potent and effective oral drug in monotherapy for the treatment of SCS. For cases with very severe hypercortisolism and/or oral intolerance, etomidate is the most effective and rapid drug for reducing cortisol levels. Bilateral adrenalectomy may be indicated in cases of life-threatening severe hypercortisolism, but UFC should be reduced before surgery to reduce the perioperative morbimortality. Prompt treatment of comorbidities and thrombo- and infection prophylaxis are recommended. In conclusion, a rapid control of hypercortisolism is vital in SCS, and for this purpose combination therapy or potent drugs with a rapid onset of action such as etomidate or osilodrostat are indicated.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 10","pages":"Article 501654"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145766125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}