Journal of Evidence-Based Dental Practice最新文献

{"title":"Information for Readers","authors":"","doi":"10.1016/S1532-3382(25)00029-6","DOIUrl":"10.1016/S1532-3382(25)00029-6","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102114"},"PeriodicalIF":4.1,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statement of Purpose/Levels of Evidence","authors":"","doi":"10.1016/S1532-3382(25)00028-4","DOIUrl":"10.1016/S1532-3382(25)00028-4","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102113"},"PeriodicalIF":4.1,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Authors","authors":"","doi":"10.1016/S1532-3382(25)00030-2","DOIUrl":"10.1016/S1532-3382(25)00030-2","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102115"},"PeriodicalIF":4.1,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Levels of Evidence—Grading System","authors":"","doi":"10.1016/S1532-3382(25)00031-4","DOIUrl":"10.1016/S1532-3382(25)00031-4","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102116"},"PeriodicalIF":4.1,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE MANAGEMENT OF TEETH IN ODONTOGENIC KERATOCYST AND AMELOBLASTOMA AND ITS PROGNOSTIC ROLE IN RECURRENCE: A SYSTEMATIC REVIEW AND META-ANALYSIS WITH TRIAL SEQUENTIAL ANALYSIS","authors":"PIERLUIGI MARIANI DDS ,&nbsp;DIANA RUSSO DDS, PhD ,&nbsp;MARCO CICCIÙ DDS, PhD ,&nbsp;LUIGI LAINO DDS, PhD","doi":"10.1016/j.jebdp.2025.102121","DOIUrl":"10.1016/j.jebdp.2025.102121","url":null,"abstract":"<div><h3>Introduction</h3><div>Odontogenic Keratocystic (OKC) and Ameloblastoma (AB) are pathological entities characterized by aggressive behavior, slow growth, local invasiveness, and high recurrence rates. The aim of this systematic review with meta-analysis and trial sequential analysis (TSA) is to assess the prognostic role of extracting involved teeth during the surgical enucleation of OKCs and ABs in terms of recurrence risk.</div></div><div><h3>Materials and Methods</h3><div>A search was conducted in PubMed/Medline, Scopus, and Web of Science databases for studies reporting data on teeth extraction and recurrence rates. This systematic review was performed according to guidelines in the Cochrane Handbook and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement. Meta-analysis was performed using the Mantel-Haenszel method with a random-effects model due to heterogeneity. The TSA was conducted to control and reduce for type I and II errors of statistical analysis.</div></div><div><h3>Results</h3><div>Six studies were identified and analyzed qualitatively and quantitatively. A total of 737 lesions (674 OKCs and 64 ABs) were included, of which 508 had involved teeth. The meta-analysis included 451 OKCs; 367 lesions were treated with teeth extraction, and in 141 cases, the teeth were preserved. The overall Risk Ratio was 0.17 (95% CI: [0.04, 0.74]; <em>P</em> &lt; .0001) for OKCs. Quantitative analysis could not be performed for ABs.</div></div><div><h3>Conclusion</h3><div>The analysis revealed that tooth extraction contextually to the enucleation of the lesion reduces the risk of recurrence by approximately 83% in the OKCs; this appears to have the same trend for ABs, but more evidence is needed.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102121"},"PeriodicalIF":4.1,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-AIDED VOLUMETRIC ROOT RESORPTION ASSESSMENT FOLLOWING PERSONALIZED FORCES IN ORTHODONTICS: PRELIMINARY RESULTS OF A RANDOMIZED CLINICAL TRIAL","authors":"NAVARRO-FRAILE ESTRELLA ,&nbsp;DEHESA-SANTOS ALEXANDRA ,&nbsp;CHEN YUN ,&nbsp;JUAN CARLOS PALMA-FERNÁNDEZ ,&nbsp;IGLESIAS-LINARES ALEJANDRO","doi":"10.1016/j.jebdp.2025.102095","DOIUrl":"10.1016/j.jebdp.2025.102095","url":null,"abstract":"<div><h3>Introduction</h3><div>External apical root resorption (EARR) is an undesirable loss of hard tissues of the tooth root frequently affecting to the maxillary incisors. The magnitude of orthodontic forces is a major treatment-related factor associated with EARR occurrence in orthodontics. The primary aim of the present randomized clinical trial was (i) to quantify the impact of a sequence of personalized force archwires on EARR compared to the conventional standard of care and (ii) compare the 3D-quantification of EARR using two quantification methods (manual or automated AI-aided segmentation).</div></div><div><h3>Material and Methods</h3><div>A superiority two arms-parallel-randomized clinical trial (RCT) was conducted to quantify the EARR of two regime forces [CONSORT-guidelines]. A total of 18/43 patients were randomly assigned [block-size: 4] to C<em>ontrol Group</em> [Ni-Ti archwires sequence] or E<em>xperimental Group</em> [selective <em>individualized</em> force archwires]. After 142 days sectorial CBCT were obtained; upper incisors were segmented manually and with AI and the volume/length of root quantified. Method error/descriptive statistics (mean; SD; range) and Student <em>t</em>-test were used to assess the differences between groups (<em>Post hoc</em> adjustment for confounders [95% CI; <em>P</em> &lt; .05]).</div></div><div><h3>Results</h3><div>The total root volume loss detected by AI was 2.44 ± 6.59 mm³ / 2.42 ± 4.75 mm³ (<em>P</em> &gt; .05) and the mean root length loss was 0.20± 0.23mm/0.42 ± 0.43 mm (<em>P</em> = .045) for control/test group, respectively. Despite length loss showed similar changes when it was quantified with both methods, manual and automatic segmentations (<em>P</em> &gt; .05), differences are observed at volume loss. The results demonstrated greater volume loss detection with manual segmentation than with AI-aided segmentation at the global level, volume by thirds, and 4 mm from the apex. However, as we approached apically, the differences equalized and even diminished, resulting in a greater loss with automatic segmentation 1 mm from the apex in the EG (<em>P</em> = .011).</div></div><div><h3>Conclusions</h3><div>A non direct-force-dependent effect over EARR (6 months) was observed. Individualized force induces slightly higher root resorption at the apical third at 1-2 mm.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102095"},"PeriodicalIF":4.1,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143464297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TWIN-MIX INJECTION REDUCES POSTOPERATIVE COMPLICATIONS AFTER LOWER THIRD MOLAR REMOVAL—A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS","authors":"ESZTER HARDI ,&nbsp;ANNA TAKÁCS ,&nbsp;BIANCA GOLZIO  NAVARRO  CAVALCANTE ,&nbsp;BENCE SZABÓ ,&nbsp;ANDREA HARNOS ,&nbsp;PÉTER HEGYI ,&nbsp;Gábor Varga ,&nbsp;ORSOLYA NÉMETH ,&nbsp;ÁRPÁD JOÓB-FANCSALY","doi":"10.1016/j.jebdp.2025.102098","DOIUrl":"10.1016/j.jebdp.2025.102098","url":null,"abstract":"<div><h3>Background</h3><div>The aim of this systematic review and meta-analysis was to assess whether pain, swelling and trismus following surgical removal of the lower third molar could be reduced by twin-mix injection.</div></div><div><h3>Materials and Methods</h3><div>MEDLINE, Embase and Cochrane Trials were searched for randomized controlled trials (RCTs) until 17th November 2022. Eight RCTs were included in the systematic review, and 7 in the meta-analysis. In this study, the twin-mix was compared with the conventional anesthetic solution. Outcomes were assessed on postoperative days 1, 3 and 7. Primary outcomes were swelling and trismus. Secondary outcomes were postoperative pain, pain score on local anesthetic injection, duration of soft tissue anesthesia, and latency of anesthesia. Risk of bias was assessed using the Cochrane ROB2 tool. Certainty of evidence was evaluated with the GRADE tool.</div></div><div><h3>Results</h3><div>On postoperative day 1, the twin-mix group showed significant reductions in facial swelling (MD: −3.51 mm; [−5.04 to −1.97]), trismus (MD: −1.7 mm; [−2.48 to −0.92]) and pain (MD: −1.07; [−1.49 to −0.65]). On day 3, swelling (MD: −4.64 mm; [−6.34 to −2.94]), trismus (MD: −1.08 mm; [−1.55 to −0.61]) and pain (MD: −0.62; [−1.09 to −0.15]) remained significantly reduced. On day 7, differences persisted for swelling (MD: −0.58 mm; [−0.76 to −0.40]) and trismus (MD: −0.42 mm; [−0.72 to −0.12]), but no significant difference was found in pain (MD: −0.29; [−0.65 to 0.07]). The twin-mix also significantly reduced pain under local anesthesia, shortened latency and prolonged duration of anesthesia.</div></div><div><h3>Conclusion</h3><div>In conclusion, the use of twin-mix is highly beneficial for pain relief, facial swelling and trismus following mandibular third molar surgical removal.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102098"},"PeriodicalIF":4.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143453029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFICACY AND SAFETY OF LIDOCAINE WITH CLONIDINE FOR MAXILLARY INFILTRATION ANESTHESIA IN PATIENTS WITH DIABETES MELLITUS TYPE 2: DOUBLE-BLIND, RANDOMIZED CLINICAL TRIAL","authors":"MARIJA S. MILIC ,&nbsp;BOZIDAR BRKOVIC ,&nbsp;MILAN VUCETIC ,&nbsp;VLADIMIR S. TODOROVIC ,&nbsp;DRAGICA STOJIC","doi":"10.1016/j.jebdp.2025.102097","DOIUrl":"10.1016/j.jebdp.2025.102097","url":null,"abstract":"<div><h3>Objectives</h3><div>This clinical trial aimed to evaluate and compare parameters of intraoral soft tissue anesthesia and cardiovascular function, and prevalence of local side effects in patients with and without diabetes mellitus type 2 (DMT2), after maxillary infiltration anesthesia obtained with 2% lidocaine with either clonidine (15mcg/ml) or epinephrine (1:100.000).</div></div><div><h3>Methods</h3><div>Sixty-three DMT2 and 52 nondiabetic (H) patients scheduled for tooth extraction were randomly assigned to receive one of the local anesthetic solutions for maxillary infiltration anesthesia: 2 mL of lidocaine with clonidine (LC) or 2 mL of lidocaine with epinephrine (LE). Parameters of soft tissue anesthesia (onset, duration and width of anesthetic field) were evaluated by <em>pinprick</em> test. Systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were monitored with patient monitor, before and until 30 minutes after anesthesia application. Presence of postoperative hyperalgesia and paresthesia during 7 postoperative days was tested with ethylene-chloride spray and monofilaments set for quantitative sensory testing, respectively. Requests for rescue analgesic were recorded for 24 hours after tooth extraction.</div></div><div><h3>Results</h3><div>Onset of maxillary infiltration anesthesia was significantly shorter in DMT2 vs. H groups (<em>P</em> &lt; .05), regardless of local anesthetic solution used. Duration of anesthesia was 59% longer in DMT2-LE vs. H-LE (<em>P</em> &lt; .05), and 28% longer in DMT2-LC vs. H-LC groups (<em>P</em> &lt; .05). Maxillary infiltration anesthesia lasted 37,9% longer in DMT2-LE vs. DMT2-LC (182.09 ± 57.86 min vs. 139.48 ± 21.86 min) (<em>P</em> &lt; .05). Width of anesthetic field was significantly increased in diabetic vs. nondiabetic participants (<em>P</em> &lt; .05), as well as in DMT2-LE vs. DMT2-LC (35.19 ± 1.67mm vs. 27.07 ± 1.06 mm) (<em>P</em> &lt; .05). SBP was significantly decreased within DM-LC and H-LC groups from 15th to 30th minute, in comparison with baseline values. Significant increase in HR was observed from 5th to 30th minute in diabetic and nondiabetic patients who received LE, compared to baseline values. Postoperative paresthesia was significantly more present in DMT2-LE vs. DMT2-LC (<em>P</em> &lt; .05), while it was not observed in nondiabetic patients.</div></div><div><h3>Conclusions</h3><div>Shorter onset and prolonged duration of maxillary infiltration anesthesia are present in DMT2 setting. Clonidine appears to be a safe alternative to epinephrine for intraoral anesthesia in DMT2, with respect to anesthetic efficacy, cardiovascular safety and prevalence of local side effects.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102097"},"PeriodicalIF":4.1,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PERIODONTITIS AS A RISK FACTOR FOR DEMENTIA: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"DONG-HEE KIM,&nbsp;GYEONG-SOON HAN","doi":"10.1016/j.jebdp.2025.102094","DOIUrl":"10.1016/j.jebdp.2025.102094","url":null,"abstract":"<div><h3>Introduction</h3><div>The association between periodontitis and dementia remains controversial. Therefore, we analyzed this association focusing on the severity of periodontitis and type of dementia.</div></div><div><h3>Methods</h3><div>We searched the PubMed, Embase, Web of Science, and gray literature (OpenGrey, ProQuest) databases from inception to June 30, 2021, and pooled the data for meta-analysis. Fixed- or random-effects models were employed to calculate odds ratios (ORs), hazard ratios (HRs), and 95% confidence intervals (CIs) to evaluate the strength of the associations between periodontitis and dementia.</div></div><div><h3>Results</h3><div>Thirteen case-control and 11 cohort studies were selected. The analysis of entire studies indicated an association between periodontitis and dementia, with an OR of 2.26 (95% CI, 1.65−3.09; <em>P</em> &lt; .0001) and HR of 1.15 (95% CI, 1.04−1.27; <em>P</em> = .0006). According to periodontitis severity, the risk of dementia was significantly associated with severe periodontitis (OR = 2.85; 95% CI, 2.16−3.74; <em>P</em> = .038), but not with less-than-moderate periodontitis (OR = 0.94; 95% CI, 0.64−1.40; <em>P</em> = .66). In particular, patients with severe periodontitis had a 6.87-fold higher risk of Alzheimer's dementia (OR = 6.87; 95% CI, 2.55−18.54; <em>P</em> = .04) and 2.92-fold higher risk of cognitive impairment (OR = 2.92, 95% CI, 2.15−3.96; <em>P</em> = .36).</div></div><div><h3>Conclusions</h3><div>We found a strong association between periodontitis and dementia, with severe periodontitis identified as a potential risk factor for Alzheimer's dementia. Therefore, timely management of periodontitis to prevent its progression may help prevent dementia.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102094"},"PeriodicalIF":4.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TRANSLATIONAL APPLICATION OF COLD ATMOSPHERIC PLASMA IN PERIODONTOLOGY AND IMPLANTOLOGY: WHERE ARE WE? A SYSTEMATIC REVIEW OF IN VIVO STUDIES IN HUMAN AND ANIMAL MODELS","authors":"GIORGIA STORNELLI ,&nbsp;GIULIA PETRUCCI ,&nbsp;VITO CARLO ALBERTO CAPONIO ,&nbsp;ELOISA SARDELLA ,&nbsp;GIUSEPPE BALICE ,&nbsp;BEATRICE FEMMINELLA ,&nbsp;MICHELE PAOLANTONIO ,&nbsp;ILARIA CELA ,&nbsp;TIRTHA RAJ ACHARYA ,&nbsp;NAYANSI JHA ,&nbsp;NAGENDRA KUMAR KAUSHIK ,&nbsp;EUN HA CHOI ,&nbsp;VALENTINA PUCA ,&nbsp;ROSSELLA GRANDE ,&nbsp;VITTORIA PERROTTI","doi":"10.1016/j.jebdp.2025.102096","DOIUrl":"10.1016/j.jebdp.2025.102096","url":null,"abstract":"<div><h3>Aim</h3><div>The utilization of cold atmospheric plasma (CAP) in dentistry presents a promising avenue for novel therapeutic interventions. This systematic review of in vivo studies aimed at summarizing the existing evidence regarding the efficacy of CAP as a treatment for biofilms associated with periodontitis and peri-implantitis. The objective was to advance the definition and standardization of protocols and facilitate the integration of CAP treatment as a chair-side practice.</div></div><div><h3>Materials and Methods</h3><div>This review was registered in PROSPERO database (CRD42023404757), and a comprehensive search was conducted following PRISMA guidelines and using PubMed, Scopus, Web of Science, and Embase databases.</div></div><div><h3>Results</h3><div>In total, 9 in vivo studies were included, 1 on humans and 8 on animal models. A notable reduction in residual bacteria when CAP was combined with conventional therapies in both periodontitis and peri-implantitis models was observed. Biochemical and histological assays demonstrated a decrease in inflammatory cytokines within crevicular fluid and oral tissues.</div></div><div><h3>Conclusions</h3><div>Current evidence suggests that CAP shows promise for periodontitis and peri-implantitis treatment, but further clinical trials with larger cohorts and standardized protocols are needed to confirm its efficacy and safety.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102096"},"PeriodicalIF":4.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143422713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}