Pub Date : 2024-08-13DOI: 10.1016/j.ctcp.2024.101895
Weijia Zhu , Xun Luo , André Oliveira Werneck , Dominika Pindus , Laurie Kramer , Arthur F. Kramer , Charles H. Hillman , Fabian Herold , Zhihao Zhang , Liye Zou
Background
and Purpose: Outdoor play is widely acknowledged for its benefits to physical health and psychological well-being, yet its relationship with school readiness remains understudied in preschoolers. To address this gap in the literature, this study investigated how outdoor play relates to cognitive and psychosocial development among a nationally representative sample of preschoolers.
Materials and method
Data on the duration of outdoor play (on weekdays and weekends) and specific cognitive and psychosocial outcome variables (i.e., early learning skills, self-regulation, social-emotional development, and flourishing) were collected via questionnaires provided to the caregivers of preschoolers. Logistic regressions were performed to examine the associations between outdoor play with cognitive and psychosocial outcomes while adjusting for covariates and calculate the odds ratio with 95 % confidence intervals (CI).
Results
Among the 10,682 preschoolers (i.e., 3-5y) included in this study (i.e., 5558 boys, Mage = 3.98 ± 0.99 years), there was a lower percentage of preschoolers engaged in outdoor play for over 3 h per day on weekdays (33.39 %) compared to weekends (56.85 %). Outdoor play in preschoolers is positively associated with various domains of school readiness, and engaging in outdoor play for more than 3 h per day is associated with more beneficial outcomes.
Conclusion
The findings of this cross-sectional study suggest that promoting outdoor play among preschoolers can be an effective strategy for enhancing cognitive, social, and emotional development in this age group although further intervention studies are required to buttress this assumption empirically.
{"title":"Nature and success: Outdoor play is linked to school readiness","authors":"Weijia Zhu , Xun Luo , André Oliveira Werneck , Dominika Pindus , Laurie Kramer , Arthur F. Kramer , Charles H. Hillman , Fabian Herold , Zhihao Zhang , Liye Zou","doi":"10.1016/j.ctcp.2024.101895","DOIUrl":"10.1016/j.ctcp.2024.101895","url":null,"abstract":"<div><h3>Background</h3><p>and Purpose: Outdoor play is widely acknowledged for its benefits to physical health and psychological well-being, yet its relationship with school readiness remains understudied in preschoolers. To address this gap in the literature, this study investigated how outdoor play relates to cognitive and psychosocial development among a nationally representative sample of preschoolers.</p></div><div><h3>Materials and method</h3><p>Data on the duration of outdoor play (on weekdays and weekends) and specific cognitive and psychosocial outcome variables (i.e., early learning skills, self-regulation, social-emotional development, and flourishing) were collected via questionnaires provided to the caregivers of preschoolers. Logistic regressions were performed to examine the associations between outdoor play with cognitive and psychosocial outcomes while adjusting for covariates and calculate the odds ratio with 95 % confidence intervals (CI).</p></div><div><h3>Results</h3><p>Among the 10,682 preschoolers (i.e., 3-5y) included in this study (i.e., 5558 boys, Mage = 3.98 ± 0.99 years), there was a lower percentage of preschoolers engaged in outdoor play for over 3 h per day on weekdays (33.39 %) compared to weekends (56.85 %). Outdoor play in preschoolers is positively associated with various domains of school readiness, and engaging in outdoor play for more than 3 h per day is associated with more beneficial outcomes.</p></div><div><h3>Conclusion</h3><p>The findings of this cross-sectional study suggest that promoting outdoor play among preschoolers can be an effective strategy for enhancing cognitive, social, and emotional development in this age group although further intervention studies are required to buttress this assumption empirically.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101895"},"PeriodicalIF":2.2,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-06DOI: 10.1016/j.ctcp.2024.101892
Wei-Cheng Chao , Jen-Chieh Huang , San-Land Young , Ching-Lin Wu , Jui-Chi Shih , Lun-De Liao , Bill Cheng
Objectives
This study aimed to explore the synergistic impact of online yoga, mindfulness practices, and probiotics on irritable bowel syndrome (IBS) by evaluating changes in physical fitness, mental health, and gut microbiota composition.
Design, setting and interventions
The six-week randomized, double-blinded, placebo-controlled trial included 31 IBS patients categorized into three groups: online yoga with probiotics (EP), online yoga with a placebo (EC), and probiotics only (P). Assessments involved physical fitness tests, subjective questionnaires (IBS-QOL, BSRS-5), and gut microbiome analysis.
Main outcome measures
Participants self-collected stool samples and were given a set of questionnaires at baseline and after six weeks of intervention. Their symptoms were measured by changes in the gut microbiota, physical fitness and quality of life, and psychological well-being.
Results
The EP group demonstrated improved cardiovascular endurance (P < 0.001) and a significant reduction in Klebsiella bacterial strains (P < 0.05). Both the EP and EC groups exhibited significantly decreased IBS-QOL scores (P < 0.001 and P < 0.05, respectively), indicating enhanced quality of life. While BSRS-5 scores decreased in both groups, the reduction was statistically insignificant.
Conclusion
Integrating online yoga, mindfulness practices, and probiotics demonstrated comprehensive benefits for IBS patients. This intervention improved physical fitness and mental well-being and positively influenced gut microbiota composition. The study highlights the potential of this multifaceted approach in managing IBS symptoms and enhancing overall health, emphasizing the relevance of the gut-muscle-brain axis in understanding and addressing IBS complexities.
Trial registration
Taiwanese Registry of Institutional Review Board IRBHP210009/CH11000259.
{"title":"Interplay of yoga, physical activity, and probiotics in irritable bowel syndrome management: A double-blind randomized study","authors":"Wei-Cheng Chao , Jen-Chieh Huang , San-Land Young , Ching-Lin Wu , Jui-Chi Shih , Lun-De Liao , Bill Cheng","doi":"10.1016/j.ctcp.2024.101892","DOIUrl":"10.1016/j.ctcp.2024.101892","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to explore the synergistic impact of online yoga, mindfulness practices, and probiotics on irritable bowel syndrome (IBS) by evaluating changes in physical fitness, mental health, and gut microbiota composition.</p></div><div><h3>Design, setting and interventions</h3><p>The six-week randomized, double-blinded, placebo-controlled trial included 31 IBS patients categorized into three groups: online yoga with probiotics (EP), online yoga with a placebo (EC), and probiotics only (P). Assessments involved physical fitness tests, subjective questionnaires (IBS-QOL, BSRS-5), and gut microbiome analysis.</p></div><div><h3>Main outcome measures</h3><p>Participants self-collected stool samples and were given a set of questionnaires at baseline and after six weeks of intervention. Their symptoms were measured by changes in the gut microbiota, physical fitness and quality of life, and psychological well-being.</p></div><div><h3>Results</h3><p>The EP group demonstrated improved cardiovascular endurance (<em>P</em> < 0.001) and a significant reduction in Klebsiella bacterial strains (<em>P</em> < 0.05). Both the EP and EC groups exhibited significantly decreased IBS-QOL scores (<em>P</em> < 0.001 and <em>P</em> < 0.05, respectively), indicating enhanced quality of life. While BSRS-5 scores decreased in both groups, the reduction was statistically insignificant.</p></div><div><h3>Conclusion</h3><p>Integrating online yoga, mindfulness practices, and probiotics demonstrated comprehensive benefits for IBS patients. This intervention improved physical fitness and mental well-being and positively influenced gut microbiota composition. The study highlights the potential of this multifaceted approach in managing IBS symptoms and enhancing overall health, emphasizing the relevance of the gut-muscle-brain axis in understanding and addressing IBS complexities.</p></div><div><h3>Trial registration</h3><p>Taiwanese Registry of Institutional Review Board IRBHP210009/CH11000259.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101892"},"PeriodicalIF":2.2,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1744388124000653/pdfft?md5=90ff955b22be18e6451ab5a32c5d64d0&pid=1-s2.0-S1744388124000653-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-05DOI: 10.1016/j.ctcp.2024.101891
Wei-Ting Lai , Hsun-Kuei Ko , Wan-Ru Chou , Pei-Yu Lee , Min-Tao Hsu
Background
and Purpose: With mindfulness being increasingly recognized for its potential to address psychological challenges related to advanced or terminal illnesses, palliative care professionals are incorporating mindfulness-based interventions into their practice. However, there is limited understanding of the practical applications of mindfulness in clinical settings, particularly for end-of-life patients. This study explored palliative care professionals’ experiences in delivering mindfulness-based therapy to end-of-life patients, thereby aiming to inform the development of effective interventions.
Materials and methods
Semi-structured interviews were conducted with 15 palliative care professionals. Participants were asked to describe their memorable experiences in applying mindfulness in a clinical setting. Data were analyzed following Moustakas's transcendental phenomenology approach.
Results
The interviews produced three themes: clinicians’ mindfulness experiences form the cornerstone of their clinical application of mindfulness; creating an optimal healing environment is essential for mindfulness practice; and patient-centric mindfulness guidance should be implemented.
Conclusion
This study underscores the critical role of mindfulness in end-of-life care, highlighting its integration into daily life by palliative care professionals. By drawing upon their own mindfulness experiences, palliative care professionals facilitated a therapeutic environment tailored to the unique needs of end-of-life patients. This patient-centered approach not only enhanced the quality of care but also fostered a healing connection rooted in compassion and empathy. The findings advocate for further education and development of mindfulness-based interventions, including group therapies, to support the holistic well-being of patients in collectivist cultures. Future research should further explore the practical applications and benefits of mindfulness in end-of-life care settings.
{"title":"Clinical application of mindfulness in end-of-life care from the perspective of palliative care professionals: A phenomenological study","authors":"Wei-Ting Lai , Hsun-Kuei Ko , Wan-Ru Chou , Pei-Yu Lee , Min-Tao Hsu","doi":"10.1016/j.ctcp.2024.101891","DOIUrl":"10.1016/j.ctcp.2024.101891","url":null,"abstract":"<div><h3>Background</h3><p>and Purpose: With mindfulness being increasingly recognized for its potential to address psychological challenges related to advanced or terminal illnesses, palliative care professionals are incorporating mindfulness-based interventions into their practice. However, there is limited understanding of the practical applications of mindfulness in clinical settings, particularly for end-of-life patients. This study explored palliative care professionals’ experiences in delivering mindfulness-based therapy to end-of-life patients, thereby aiming to inform the development of effective interventions.</p></div><div><h3>Materials and methods</h3><p>Semi-structured interviews were conducted with 15 palliative care professionals. Participants were asked to describe their memorable experiences in applying mindfulness in a clinical setting. Data were analyzed following Moustakas's transcendental phenomenology approach.</p></div><div><h3>Results</h3><p>The interviews produced three themes: clinicians’ mindfulness experiences form the cornerstone of their clinical application of mindfulness; creating an optimal healing environment is essential for mindfulness practice; and patient-centric mindfulness guidance should be implemented.</p></div><div><h3>Conclusion</h3><p>This study underscores the critical role of mindfulness in end-of-life care, highlighting its integration into daily life by palliative care professionals. By drawing upon their own mindfulness experiences, palliative care professionals facilitated a therapeutic environment tailored to the unique needs of end-of-life patients. This patient-centered approach not only enhanced the quality of care but also fostered a healing connection rooted in compassion and empathy. The findings advocate for further education and development of mindfulness-based interventions, including group therapies, to support the holistic well-being of patients in collectivist cultures. Future research should further explore the practical applications and benefits of mindfulness in end-of-life care settings.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101891"},"PeriodicalIF":2.2,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-05DOI: 10.1016/j.ctcp.2024.101893
Kaiqi Guan , Fabian Herold , Neville Owen , Boris Cheval , Zijun Liu , Markus Gerber , Arthur F. Kramer , Alyx Taylor , Anthony Delli Paoli , Liye Zou
Background
Contemporary 24-h movement behavior (24-HMB) guidelines provide recommendations on time spent on physical activity (PA), screen time (ST), and sleep (SL). There is evidence of physiological and psychological health benefits associated with meeting such guidelines. However, the prevalence of meeting 24-HMB guidelines among youth prescribed eyeglasses/contact lenses is less clear. The primary purpose of this cross-sectional analysis was to examine the prevalence of partially or fully meeting 24-HMB guidelines in U.S. youth prescribed eyeglasses/contact lenses, and variations in meeting the guidelines by demographic, health status, and environmental attributes.
Methods
Data from the 2021 National Survey of Children's Health (NSCH) yielded a target subpopulation of 8523 youth aged 6–17 years (54.22 % girls) prescribed eyeglasses/contact lenses. The representative sample of US children and adolescents was used to estimate the prevalence of meeting 24-HMB guidelines, and a multinomial logistic regression analysis was conducted to examine the odds of meeting 24-HMB guidelines by demographic, health status, and environmental variables.
Results
Overall, only 6.57 % met all three 24-HMB guidelines, 23.74 % did not meet any of the three 24-HMB guidelines, and 3.57 %, 10.88 %, and 29.98 % met single guidelines for physical activity, screen time, or sleep duration, respectively, while 25.27 % met any of two 24-HMB guidelines. Female participants were less likely to meet PA + SL guidelines (OR = 0.57, 95 % CI [0.38, 0.56]) but more likely to meet ST + SL guidelines (OR = 1.52, 95 % CI [1.20, 1.91]). Hispanic participants were less likely to meet PA + ST (OR = 0.28, 95 % CI [0.14, 0.52]) guidelines and all three guidelines (OR = 0.41, 95 % CI [0.23, 0.71]) while participants identified as black (OR = 0.33, 95 % CI [0.21, 0.51]) were significantly less likely to meet ST + SL guidelines. With respect to health status, overweight status, repeated/chronic physical pain, and born premature, were detrimentally associated with meeting two or more 24-HMB guidelines. Living in neighborhoods with parks or playgrounds and neighborhood safety were positively linked to meeting the guidelines while living in neighborhoods with sidewalks or walking paths was negatively linked to meeting PA + ST guidelines.
Conclusion
In U.S. youth prescribed eyeglasses/contact lenses the prevalence of meeting all three 24-HMB guidelines was low, especially the low prevalence observed in female participants, Hispanic and black participants, participants with overweight status, repeated/chronic pain, born premature, living in neighborhoods with sidewalks. Policy makers should take initiative to promote integrated guidelines among this special age group for health benefits.
背景:当代的 24 小时运动行为(24-HMB)指南对体育活动(PA)、屏幕时间(ST)和睡眠时间(SL)提出了建议。有证据表明,符合这些指南对生理和心理健康有益。然而,在配戴眼镜/隐形眼镜的青少年中,符合 24-HMB 指南的比例并不明确。本横断面分析的主要目的是研究美国青少年配戴眼镜/隐形眼镜时部分或完全符合 24-HMB 指导原则的比例,以及人口、健康状况和环境属性对符合指导原则的影响:2021 年全国儿童健康调查(NSCH)的数据产生了一个目标亚人群,即 8523 名 6-17 岁青少年(54.22% 为女孩)配戴眼镜/隐形眼镜。美国儿童和青少年的代表性样本被用来估算符合 24-HMB 指南的流行率,并进行了多项式逻辑回归分析,根据人口统计学、健康状况和环境变量来研究符合 24-HMB 指南的几率:总体而言,只有 6.57% 的人符合全部三项 24-HMB 指南,23.74% 的人不符合三项 24-HMB 指南中的任何一项,3.57%、10.88% 和 29.98% 的人分别符合体育锻炼、屏幕时间或睡眠时间的单项指南,25.27% 的人符合两项 24-HMB 指南中的任何一项。女性参与者符合 PA + SL 指导方针的可能性较低(OR = 0.57,95 % CI [0.38,0.56]),但符合 ST + SL 指导方针的可能性较高(OR = 1.52,95 % CI [1.20,1.91])。西班牙裔参与者不太可能符合 PA + ST(OR = 0.28,95 % CI [0.14,0.52])指南和所有三项指南(OR = 0.41,95 % CI [0.23,0.71]),而被认定为黑人的参与者(OR = 0.33,95 % CI [0.21,0.51])则明显不太可能符合 ST + SL 指南。在健康状况方面,超重状况、反复/慢性身体疼痛以及早产与符合两项或更多 24-HMB 指南有不利关系。居住在有公园或操场的社区以及社区安全与达到准则要求呈正相关,而居住在有人行道或步行道的社区与达到 PA + ST 准则要求呈负相关:在配戴眼镜/隐形眼镜的美国青少年中,符合所有三项 24-HMB 指导原则的比例较低,尤其是女性参与者、西班牙裔和黑人参与者、超重者、反复/慢性疼痛者、早产儿、居住在有人行道的社区的青少年。决策者应主动在这一特殊年龄组中推广综合指南,以促进健康。
{"title":"Prevalence and correlates of meeting 24-hour movement behavior guidelines among 8523 youth prescribed eyeglasses/contact lenses","authors":"Kaiqi Guan , Fabian Herold , Neville Owen , Boris Cheval , Zijun Liu , Markus Gerber , Arthur F. Kramer , Alyx Taylor , Anthony Delli Paoli , Liye Zou","doi":"10.1016/j.ctcp.2024.101893","DOIUrl":"10.1016/j.ctcp.2024.101893","url":null,"abstract":"<div><h3>Background</h3><p>Contemporary 24-h movement behavior (24-HMB) guidelines provide recommendations on time spent on physical activity (PA), screen time (ST), and sleep (SL). There is evidence of physiological and psychological health benefits associated with meeting such guidelines. However, the prevalence of meeting 24-HMB guidelines among youth prescribed eyeglasses/contact lenses is less clear. The primary purpose of this cross-sectional analysis was to examine the prevalence of partially or fully meeting 24-HMB guidelines in U.S. youth prescribed eyeglasses/contact lenses, and variations in meeting the guidelines by demographic, health status, and environmental attributes.</p></div><div><h3>Methods</h3><p>Data from the 2021 National Survey of Children's Health (NSCH) yielded a target subpopulation of 8523 youth aged 6–17 years (54.22 % girls) prescribed eyeglasses/contact lenses. The representative sample of US children and adolescents was used to estimate the prevalence of meeting 24-HMB guidelines, and a multinomial logistic regression analysis was conducted to examine the odds of meeting 24-HMB guidelines by demographic, health status, and environmental variables.</p></div><div><h3>Results</h3><p>Overall, only 6.57 % met all three 24-HMB guidelines, 23.74 % did not meet any of the three 24-HMB guidelines, and 3.57 %, 10.88 %, and 29.98 % met single guidelines for physical activity, screen time, or sleep duration, respectively, while 25.27 % met any of two 24-HMB guidelines. Female participants were less likely to meet PA + SL guidelines (OR = 0.57, 95 % CI [0.38, 0.56]) but more likely to meet ST + SL guidelines (OR = 1.52, 95 % CI [1.20, 1.91]). Hispanic participants were less likely to meet PA + ST (OR = 0.28, 95 % CI [0.14, 0.52]) guidelines and all three guidelines (OR = 0.41, 95 % CI [0.23, 0.71]) while participants identified as black (OR = 0.33, 95 % CI [0.21, 0.51]) were significantly less likely to meet ST + SL guidelines. With respect to health status, overweight status, repeated/chronic physical pain, and born premature, were detrimentally associated with meeting two or more 24-HMB guidelines. Living in neighborhoods with parks or playgrounds and neighborhood safety were positively linked to meeting the guidelines while living in neighborhoods with sidewalks or walking paths was negatively linked to meeting PA + ST guidelines.</p></div><div><h3>Conclusion</h3><p>In U.S. youth prescribed eyeglasses/contact lenses the prevalence of meeting all three 24-HMB guidelines was low, especially the low prevalence observed in female participants, Hispanic and black participants, participants with overweight status, repeated/chronic pain, born premature, living in neighborhoods with sidewalks. Policy makers should take initiative to promote integrated guidelines among this special age group for health benefits.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101893"},"PeriodicalIF":2.2,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-03DOI: 10.1016/j.ctcp.2024.101890
Obiora Anichebe , Anselm U. Anibueze , Victoria Anum , Edith Ugochi Ohaja , Cindy Anene Ezeugwu , Nelson Torti Obasi , Elizabeth Odachi Onogwu , Verlumun Celestine Gever
This study examined the usefulness of drama and music therapies as communication strategies for reducing symptoms of post-traumatic stress disorder (PTSD) and generalised anxiety disorder (GAD) among school children (aged 10–16) who were victims of the 2022 floods in Nigeria. The researchers randomly assigned the children to control (n = 122) drama therapy (n = 120) and music therapy (n = 120) groups. The result of the study revealed that after the intervention, school children in the drama and music therapies (unlike those in the control group) reported a significant reduction in their PTSD and GAD symptoms; the reduction achieved statistical significance (p = 0.001, ηp2 = 0.48). Further results revealed a significant interactive effect of gender (p = 0.001) with boys reporting a significant reduction more than girls. The results showed that drama therapy contributed more to reducing PTSD symptoms, while music therapy contributed more to reducing GAD symptoms. The difference did not achieve statistical significance (p = 0.23). The researchers conclude that both drama and music therapies were associated with reduced symptoms, indicating the interventions may be beneficial therapies.
{"title":"Effectiveness of drama and music therapies as health communication interventions for reducing anxiety and posttraumatic disorders among children-victims of flood","authors":"Obiora Anichebe , Anselm U. Anibueze , Victoria Anum , Edith Ugochi Ohaja , Cindy Anene Ezeugwu , Nelson Torti Obasi , Elizabeth Odachi Onogwu , Verlumun Celestine Gever","doi":"10.1016/j.ctcp.2024.101890","DOIUrl":"10.1016/j.ctcp.2024.101890","url":null,"abstract":"<div><p>This study examined the usefulness of drama and music therapies as communication strategies for reducing symptoms of post-traumatic stress disorder (PTSD) and generalised anxiety disorder (GAD) among school children (aged 10–16) who were victims of the 2022 floods in Nigeria. The researchers randomly assigned the children to control (n = 122) drama therapy (n = 120) and music therapy (n = 120) groups. The result of the study revealed that after the intervention, school children in the drama and music therapies (unlike those in the control group) reported a significant reduction in their PTSD and GAD symptoms; the reduction achieved statistical significance (<em>p</em> = 0.001, η<sub>p</sub><sup>2</sup> = 0.48). Further results revealed a significant interactive effect of gender (<em>p</em> = 0.001) with boys reporting a significant reduction more than girls. The results showed that drama therapy contributed more to reducing PTSD symptoms, while music therapy contributed more to reducing GAD symptoms. The difference did not achieve statistical significance (<em>p</em> = 0.23). The researchers conclude that both drama and music therapies were associated with reduced symptoms, indicating the interventions may be beneficial therapies.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101890"},"PeriodicalIF":2.2,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141899175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-29DOI: 10.1016/j.ctcp.2024.101889
Chunliang Wang , Yuzhu Fan , Guiting Liang , Qiang Wang , Hui Gao , Junhong Duan
Background and purpose
A growing number of studies have investigated the efficacy of acupuncture in the treatment of painful diabetic peripheral neuropathy (PDPN), but the findings of these studies have generated conflicting results. This study therefore aimed to assess the efficacy of acupuncture for treating PDPN so as to offer more conclusive results.
Methods
Seven databases were systematically searched for studies published up until December 1, 2023. All randomized controlled trials (RCTs) of acupuncture for PDPN with visual analog scale (VAS) for pain score were included. Study selection, data extraction, and evaluation were conducted independently by researchers. The Risk of Bias 2 (RoB2) tool was employed to assess the risk of bias. From this sample, the mean difference (MD), 95 % confidence intervals (CI), publication bias, and heterogeneity were then computed.
Results
The manual acupuncture group exhibited a significant decrease in the VAS for pain score compared with the routine care group (p < 0.0001; MD = −1.45 [95 % CI, −1.97 to −0.93], I2 = 84 %). The real acupuncture group demonstrated a greater reduction in VAS scores than the sham acupuncture group (p = 0.004; MD = −0.97 [95 % CI, −1.63 to −0.31], I2 = 65 %). Additionally, the acupuncture group showed improvements in sensory nerve conduction velocity (SNCV, p < 0.0001; MD = 2.29 [95 % CI, 1.79 to 2.78], I2 = 14 %) as well as motor nerve conduction velocity (MNCV, p < 0.0001; MD = 2.87 [95 % CI, 2.46 to 3.27], I2 = 0). Different durations of acupuncture treatment, including 6–10 weeks and 3–4 weeks, demonstrated a significant reduction in VAS scores compared with the routine care group.
Conclusion
This meta-analysis provides preliminary evidence for the claim that acupuncture has the potential to alleviate PDPN symptoms and improve SNCV and MNCV. However, high-quality RCTs are needed to offer further evidence and thus better substantiate such a contention.
{"title":"Acupuncture for the treatment of painful diabetic peripheral neuropathy: A systematic review and meta-analysis","authors":"Chunliang Wang , Yuzhu Fan , Guiting Liang , Qiang Wang , Hui Gao , Junhong Duan","doi":"10.1016/j.ctcp.2024.101889","DOIUrl":"10.1016/j.ctcp.2024.101889","url":null,"abstract":"<div><h3>Background and purpose</h3><p>A growing number of studies have investigated the efficacy of acupuncture in the treatment of painful diabetic peripheral neuropathy (PDPN), but the findings of these studies have generated conflicting results. This study therefore aimed to assess the efficacy of acupuncture for treating PDPN so as to offer more conclusive results.</p></div><div><h3>Methods</h3><p>Seven databases were systematically searched for studies published up until December 1, 2023. All randomized controlled trials (RCTs) of acupuncture for PDPN with visual analog scale (VAS) for pain score were included. Study selection, data extraction, and evaluation were conducted independently by researchers. The Risk of Bias 2 (RoB2) tool was employed to assess the risk of bias. From this sample, the mean difference (MD), 95 % confidence intervals (CI), publication bias, and heterogeneity were then computed.</p></div><div><h3>Results</h3><p>The manual acupuncture group exhibited a significant decrease in the VAS for pain score compared with the routine care group (p < 0.0001; MD = −1.45 [95 % CI, −1.97 to −0.93], I<sup>2</sup> = 84 %). The real acupuncture group demonstrated a greater reduction in VAS scores than the sham acupuncture group (p = 0.004; MD = −0.97 [95 % CI, −1.63 to −0.31], I<sup>2</sup> = 65 %). Additionally, the acupuncture group showed improvements in sensory nerve conduction velocity (SNCV, p < 0.0001; MD = 2.29 [95 % CI, 1.79 to 2.78], I<sup>2</sup> = 14 %) as well as motor nerve conduction velocity (MNCV, p < 0.0001; MD = 2.87 [95 % CI, 2.46 to 3.27], I<sup>2</sup> = 0). Different durations of acupuncture treatment, including 6–10 weeks and 3–4 weeks, demonstrated a significant reduction in VAS scores compared with the routine care group.</p></div><div><h3>Conclusion</h3><p>This meta-analysis provides preliminary evidence for the claim that acupuncture has the potential to alleviate PDPN symptoms and improve SNCV and MNCV. However, high-quality RCTs are needed to offer further evidence and thus better substantiate such a contention.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101889"},"PeriodicalIF":2.2,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1744388124000628/pdfft?md5=4640b5b0666017d6bcd05545004098fd&pid=1-s2.0-S1744388124000628-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-28DOI: 10.1016/j.ctcp.2024.101886
Jingyu Xu , Baojuan Wang , Wenbin Zhu , Haiqing Ao
Objective
This study aims to ascertain the effectiveness of creative art therapy (CAT) in alleviating symptoms of postpartum depression (PPD).
Methods
A systematic review of all randomized controlled trials of CAT for PPD was conducted. Eight bibliographic databases, namely, PubMed, The Cochrane Library, Embase, Web of Science, CNKI, Wanfang Database, VIP Database, and China Biomedical Literature Database were searched digitally, while Google Scholar database was searched manually for a comprehensive literature search. The search period is from the establishment of the database to May 2024. Literature screening and data extraction were conducted independently by two researchers, and the risk of bias in the included studies was evaluated. Finally, RevMan5.3 software and STATA 15.1 software were used for meta-analysis.
Results
Twelve studies, including 1633 patients, were included in this review. The results of our meta-analysis revealed that the intervention group was significantly better than the control group in depression [SMD = −0.882, 95 % CI: −1.256 to −0.508, P < 0.001][WMD = 0.680, 95 % CI: 0.407–0.953, P < 0.001], anxiety [SMD = −0.712, 95 % CI: −1.405 to −0.019, P = 0.044], and personal state [WMD = −5.180, 95 % CI: −5.869 to −4.491, P < 0.001][SMD = 0.388, 95 % CI: 0.132–0.643, P = 0.003], and the difference was statistically significant. Sensitivity analysis revealed that the above results were stable.
Conclusion
CAT (music and creative games) was found to be effective in relieving depression, anxiety, and personal state in patients with PPD. Though CAT appears to be worthy of clinical application, more high-quality and large-sample studies are required to explore various aspects in the current context.
{"title":"Creative art therapy for postpartum depression: A systematic review and meta-analysis","authors":"Jingyu Xu , Baojuan Wang , Wenbin Zhu , Haiqing Ao","doi":"10.1016/j.ctcp.2024.101886","DOIUrl":"10.1016/j.ctcp.2024.101886","url":null,"abstract":"<div><h3>Objective</h3><p>This study aims to ascertain the effectiveness of creative art therapy (CAT) in alleviating symptoms of postpartum depression (PPD).</p></div><div><h3>Methods</h3><p>A systematic review of all randomized controlled trials of CAT for PPD was conducted. Eight bibliographic databases, namely, PubMed, The Cochrane Library, Embase, Web of Science, CNKI, Wanfang Database, VIP Database, and China Biomedical Literature Database were searched digitally, while Google Scholar database was searched manually for a comprehensive literature search. The search period is from the establishment of the database to May 2024. Literature screening and data extraction were conducted independently by two researchers, and the risk of bias in the included studies was evaluated. Finally, RevMan5.3 software and STATA 15.1 software were used for meta-analysis.</p></div><div><h3>Results</h3><p>Twelve studies, including 1633 patients, were included in this review. The results of our meta-analysis revealed that the intervention group was significantly better than the control group in depression [SMD = −0.882, 95 % CI: −1.256 to −0.508, <em>P</em> < 0.001][WMD = 0.680, 95 % CI: 0.407–0.953, <em>P</em> < 0.001], anxiety [SMD = −0.712, 95 % CI: −1.405 to −0.019, <em>P</em> = 0.044], and personal state [WMD = −5.180, 95 % CI: −5.869 to −4.491, <em>P</em> < 0.001][SMD = 0.388, 95 % CI: 0.132–0.643, <em>P</em> = 0.003], and the difference was statistically significant. Sensitivity analysis revealed that the above results were stable.</p></div><div><h3>Conclusion</h3><p>CAT (music and creative games) was found to be effective in relieving depression, anxiety, and personal state in patients with PPD. Though CAT appears to be worthy of clinical application, more high-quality and large-sample studies are required to explore various aspects in the current context.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101886"},"PeriodicalIF":2.2,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-25DOI: 10.1016/j.ctcp.2024.101888
Jorge Furtado de Campos Júnior, Laís Campos de Oliveira, Alex Lopes dos Reis, Laura Isabel Martins de Almeida, Larissa Victória Branco, Raphael Gonçalves de Oliveira
Background
and Purpose: Pilates exercises have been recommended to improve postural balance and reduce the risk of falls in older adults. However, the certainty of these recommendations remains unclear. In this sense, our objective was to update the literature and verify the effects of Pilates on postural balance and the risk of falls in this population.
Methods
A systematic search was conducted across multiple databases, including PubMed, EMBASE, CENTRAL, CINAHL, Web of Science, SPORTDiscus, LILACS, and PEDro, on April 17, 2023. The methodological quality of the studies was assessed using the PEDro scale, and the certainty of evidence was evaluated using the GRADE system. Meta-analysis calculations were performed by standardized mean difference (SMD).
Results
A total of 39 studies, involving 1770 participants, were included in the systematic review. Only 14 studies exhibited satisfactory methodological quality. Evidence with very low to moderate certainty showed that Pilates was significantly superior to control groups on indicators of dynamic postural balance (SMD = 1.60 to 0.72), static postural balance (SMD = 0.37 to 0.25), and general state of balance (SMD = 0.76), but not to reduce the number and fear of falls. Furthermore, Pilates was comparable to other forms of exercise for these outcomes.
Conclusions
Pilates can be recommended to enhance static and dynamic postural balance in older adults, but not to reduce the number of falls or the fear of falling. Given that no outcomes showed high certainty of evidence, future studies may alter these findings.
{"title":"Effects of Pilates exercises on postural balance and reduced risk of falls in older adults: A systematic review and meta-analysis","authors":"Jorge Furtado de Campos Júnior, Laís Campos de Oliveira, Alex Lopes dos Reis, Laura Isabel Martins de Almeida, Larissa Victória Branco, Raphael Gonçalves de Oliveira","doi":"10.1016/j.ctcp.2024.101888","DOIUrl":"10.1016/j.ctcp.2024.101888","url":null,"abstract":"<div><h3>Background</h3><p>and Purpose: Pilates exercises have been recommended to improve postural balance and reduce the risk of falls in older adults. However, the certainty of these recommendations remains unclear. In this sense, our objective was to update the literature and verify the effects of Pilates on postural balance and the risk of falls in this population.</p></div><div><h3>Methods</h3><p>A systematic search was conducted across multiple databases, including PubMed, EMBASE, CENTRAL, CINAHL, Web of Science, SPORTDiscus, LILACS, and PEDro, on April 17, 2023. The methodological quality of the studies was assessed using the PEDro scale, and the certainty of evidence was evaluated using the GRADE system. Meta-analysis calculations were performed by standardized mean difference (SMD).</p></div><div><h3>Results</h3><p>A total of 39 studies, involving 1770 participants, were included in the systematic review. Only 14 studies exhibited satisfactory methodological quality. Evidence with very low to moderate certainty showed that Pilates was significantly superior to control groups on indicators of dynamic postural balance (SMD = 1.60 to 0.72), static postural balance (SMD = 0.37 to 0.25), and general state of balance (SMD = 0.76), but not to reduce the number and fear of falls. Furthermore, Pilates was comparable to other forms of exercise for these outcomes.</p></div><div><h3>Conclusions</h3><p>Pilates can be recommended to enhance static and dynamic postural balance in older adults, but not to reduce the number of falls or the fear of falling. Given that no outcomes showed high certainty of evidence, future studies may alter these findings.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101888"},"PeriodicalIF":2.2,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-24DOI: 10.1016/j.ctcp.2024.101887
Ziyi Yang , Xinxing Li , Wook Song , Yanjie Zhang
Objective
To diminish the negative influence of sarcopenia on senior adults, the study aimed to investigate the association between adherence to 24-h movement behavior guidelines (physical activity, sedentary behavior, sleep duration) and the risk of sarcopenia among individuals aged ≥55 years in five low- and middle-income countries (LMICs).
Methods
A total of 16,503 adults aged ≥55 years were included in this cross-sectional study. The study utilized data from Global Aging and Adult Health Survey (SAGE). Participants reported their information about physical activity, sedentary behavior, and sleep duration using the questionnaire. Sarcopenia was identified as low skeletal muscle mass with a diminished gait speed or weakened handgrip strength. Multiple logistic regression models were used to investigate the association between adherence to 24-h movement behavior guidelines and the risk of sarcopenia.
Results
Merely 32.73 % of participants met all three 24-h movement behavior guidelines (physical activity, less sedentary behavior, sleep). Meeting all three guidelines (p < 0.01) was significantly associated with a lower risk of sarcopenia. Meeting physical activity only (p < 0.05), or meeting both physical activity and sedentary behaivor (p < 0.05), or meeting both physical activity and sleep duration (p < 0.01) guidelines were also associated with a reduced risk of sarcopenia. Moreover, adults aged 65+ years who adhered to 24-h movement behavior guidelines exhibited a significantly reduced risk of developing sarcopenia.
Conclusion
The findings suggest that the adherence to 24-h movement behavior guidelines for regular physical activity, limited sedentary behavior, and sufficient sleep duration was associated with a reduced risk of sarcopenia in adults aged ≥55 years in five LMICs.
{"title":"Associations between meeting 24-h movement guidelines and sarcopenia risk among adults aged ≥ 55 years in five low- and middle-income countries","authors":"Ziyi Yang , Xinxing Li , Wook Song , Yanjie Zhang","doi":"10.1016/j.ctcp.2024.101887","DOIUrl":"10.1016/j.ctcp.2024.101887","url":null,"abstract":"<div><h3>Objective</h3><p>To diminish the negative influence of sarcopenia on senior adults, the study aimed to investigate the association between adherence to 24-h movement behavior guidelines (physical activity, sedentary behavior, sleep duration) and the risk of sarcopenia among individuals aged ≥55 years in five low- and middle-income countries (LMICs).</p></div><div><h3>Methods</h3><p>A total of 16,503 adults aged ≥55 years were included in this cross-sectional study. The study utilized data from Global Aging and Adult Health Survey (SAGE). Participants reported their information about physical activity, sedentary behavior, and sleep duration using the questionnaire. Sarcopenia was identified as low skeletal muscle mass with a diminished gait speed or weakened handgrip strength. Multiple logistic regression models were used to investigate the association between adherence to 24-h movement behavior guidelines and the risk of sarcopenia.</p></div><div><h3>Results</h3><p>Merely 32.73 % of participants met all three 24-h movement behavior guidelines (physical activity, less sedentary behavior, sleep). Meeting all three guidelines (p < 0.01) was significantly associated with a lower risk of sarcopenia. Meeting physical activity only (p < 0.05), or meeting both physical activity and sedentary behaivor (p < 0.05), or meeting both physical activity and sleep duration (p < 0.01) guidelines were also associated with a reduced risk of sarcopenia. Moreover, adults aged 65+ years who adhered to 24-h movement behavior guidelines exhibited a significantly reduced risk of developing sarcopenia.</p></div><div><h3>Conclusion</h3><p>The findings suggest that the adherence to 24-h movement behavior guidelines for regular physical activity, limited sedentary behavior, and sufficient sleep duration was associated with a reduced risk of sarcopenia in adults aged ≥55 years in five LMICs.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101887"},"PeriodicalIF":2.2,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141848306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-22DOI: 10.1016/j.ctcp.2024.101885
Li-ping Fan , Alonso Quijano-Ruiz , Chen Wang , Hong-wei Zhao , Dan-ni Wang , Han-ming Wu , Lin Liu , Yi-hong Zhan , Xian-bao Zhou
Background and purpose
Previous studies have suggested that music listening has the potential to positively affect cognitive functions and mood in individuals with post-stroke cognitive impairment (PSCI), with a preference for self-selected music likely to yield better outcomes. However, there is insufficient clinical evidence to suggest the use of music listening in routine rehabilitation care to treat PSCI. This randomized control trial (RCT) aims to investigate the effects of personalized music listening on mood improvement, activities of daily living (ADLs), and cognitive functions in individuals with PSCI.
Materials and methods
A total of 34 patients with PSCI were randomly assigned to either the music group or the control group. Patients in the music group underwent a three-month personalized music-listening intervention. The intervention involved listening to a personalized playlist tailored to each individual's cultural, ethnic, and social background, life experiences, and personal music preferences. In contrast, the control group patients listened to white noise as a placebo. Cognitive function, neurological function, mood, and ADLs were assessed.
Results
After three months of treatment, the music group showed significantly higher Montreal Cognitive Assessment (MoCA) scores compared to the control group (p=0.027), particularly in the domains of delayed recall (p=0.019) and orientation (p=0.023). Moreover, the music group demonstrated significantly better scores in National Institutes of Health Stroke Scale (NIHSS) (p=0.008), Barthel Index (BI) (p=0.019), and Zarit Caregiver Burden Interview (ZBI) (p=0.008) compared to the control group. No effects were found on mood as measured by the Hamilton Anxiety Rating Scale (HAMA) and the Hamilton Depression Rating Scale (HAMD).
Conclusion
Personalized music listening promotes the recovery of cognitive and neurological functions, improves ADLs, and reduces caregiver burden in patients with PSCI.
{"title":"Effects of personalized music listening on post-stroke cognitive impairment: A randomized controlled trial","authors":"Li-ping Fan , Alonso Quijano-Ruiz , Chen Wang , Hong-wei Zhao , Dan-ni Wang , Han-ming Wu , Lin Liu , Yi-hong Zhan , Xian-bao Zhou","doi":"10.1016/j.ctcp.2024.101885","DOIUrl":"10.1016/j.ctcp.2024.101885","url":null,"abstract":"<div><h3>Background and purpose</h3><p>Previous studies have suggested that music listening has the potential to positively affect cognitive functions and mood in individuals with post-stroke cognitive impairment (PSCI), with a preference for self-selected music likely to yield better outcomes. However, there is insufficient clinical evidence to suggest the use of music listening in routine rehabilitation care to treat PSCI. This randomized control trial (RCT) aims to investigate the effects of personalized music listening on mood improvement, activities of daily living (ADLs), and cognitive functions in individuals with PSCI.</p></div><div><h3>Materials and methods</h3><p>A total of 34 patients with PSCI were randomly assigned to either the music group or the control group. Patients in the music group underwent a three-month personalized music-listening intervention. The intervention involved listening to a personalized playlist tailored to each individual's cultural, ethnic, and social background, life experiences, and personal music preferences. In contrast, the control group patients listened to white noise as a placebo. Cognitive function, neurological function, mood, and ADLs were assessed.</p></div><div><h3>Results</h3><p>After three months of treatment, the music group showed significantly higher Montreal Cognitive Assessment (MoCA) scores compared to the control group (<em>p=</em>0.027), particularly in the domains of delayed recall (<em>p=</em>0.019) and orientation (<em>p=</em>0.023). Moreover, the music group demonstrated significantly better scores in National Institutes of Health Stroke Scale (NIHSS) (<em>p=</em>0.008), Barthel Index (BI) (<em>p=</em>0.019), and Zarit Caregiver Burden Interview (ZBI) (<em>p=</em>0.008) compared to the control group. No effects were found on mood as measured by the Hamilton Anxiety Rating Scale (HAMA) and the Hamilton Depression Rating Scale (HAMD).</p></div><div><h3>Conclusion</h3><p>Personalized music listening promotes the recovery of cognitive and neurological functions, improves ADLs, and reduces caregiver burden in patients with PSCI.</p></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"57 ","pages":"Article 101885"},"PeriodicalIF":2.2,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1744388124000586/pdfft?md5=70620bd24cee891900e23e8062018a81&pid=1-s2.0-S1744388124000586-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141847504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}