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The effect of an aromatic solution applied after percutaneous nephrolithotomy on sore throat, thirst, and nausea-vomiting: A randomised controlled trial 经皮肾镜取石术后应用芳香溶液对喉咙痛、口渴和恶心呕吐的影响:一项随机对照试验。
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.ctcp.2024.101934
Esma Gökçe , Şeyma Yurtseven , Sevban Arslan , Mustafa Süren , Nebil Akdoğan

Background and purpose

Common postoperative symptoms are known to impede recovery, indicating the necessity for non-pharmacological alternatives to address these symptoms. This study aimed to investigate the effect of an aromatic solution prepared from lavender and ginger oil on sore throat, thirst, and nausea-vomiting after percutaneous nephrolithotomy (PNL) surgery.

Materials and methods

The trial used an experimental, double-blind randomised controlled group design with three arms. It was conducted between 2021 and 2023 in the urology department of a hospital, involving 110 patients (37 experimental, 37 placebo, 36 control) who underwent PNL. A personal information form, a visual analogue scale (VAS) for sore throat and thirst, and a verbal descriptive scale (VDS) for nausea and vomiting were used. The prepared aromatic solution was applied as a mouth spray at 0, 2, 4, 6, and 8 h postoperatively.

Results

A statistically significant decrease in sore throat scores was observed in the experimental group compared to the placebo and control groups following the intervention. Thirst levels decreased in both the placebo and experimental groups, with the experimental group showing lower thirst scores than the other groups. Additionally, the experimental group showed a significant reduction in nausea and vomiting scores compared to the other groups.

Conclusion

This study found that the aromatic solution had beneficial effects on sore throat, thirst, and nausea-vomiting in the postoperative period. To our knowledge, this is among the first studies exploring combined effects of lavender and ginger oils on postoperative symptoms after PNL surgery, potentially offering new insights to the literature.

Clinicaltrials gov id

NCT05522023
背景和目的:已知常见的术后症状会阻碍恢复,表明有必要采用非药物替代方法来解决这些症状。本研究旨在探讨薰衣草姜油芳香溶液对经皮肾镜取石术(PNL)术后喉咙痛、口渴和恶心呕吐的影响。材料与方法:本试验采用试验性、双盲、随机对照三组设计。该研究于2021年至2023年在一家医院的泌尿科进行,涉及110名接受PNL的患者(37名实验组,37名安慰剂组,36名对照组)。使用个人信息表、喉咙痛和口渴的视觉模拟量表(VAS)和恶心和呕吐的言语描述量表(VDS)。制备的芳香溶液于术后0、2、4、6、8 h口喷。结果:与安慰剂组和对照组相比,实验组在干预后喉咙痛评分有统计学意义的下降。安慰剂组和实验组的口渴程度都有所下降,实验组的口渴得分低于其他组。此外,与其他组相比,实验组的恶心和呕吐评分显著降低。结论:本研究发现芳香溶液对术后喉咙痛、口渴、恶心呕吐有良好的治疗作用。据我们所知,这是首批探索薰衣草和生姜油对PNL手术后症状联合作用的研究之一,可能为文献提供新的见解。临床试验网站:NCT05522023。
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引用次数: 0
Assessing barriers to meditation in patients with substance use disorder 评估物质使用障碍患者的冥想障碍
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-27 DOI: 10.1016/j.ctcp.2025.101957
Tiffany Champagne-Langabeer , A. Sarah Cohen , Audrey Lopez , Christine Bakos-Block , Alisha Campbell , Bhanumathi Gopal , Marylou Cardenas-Turanzas , Ashmita Poudel , Chelsea Ratcliff , Aila Malik , Radha Korupolu

Background and purpose

Individuals living with substance use disorder (SUD) often face unique challenges that can hinder their engagement in beneficial practices like meditation, which has been shown to support recovery and well-being. This study aimed to explore the perceived barriers to meditation with SUD, identify key obstacles, and inform future interventions that promote the adoption of a personal practice.

Materials and methods

We conducted a cross-sectional analytic study with a convenience sample of participants attending a treatment center for SUD. Data collected included demographics, SUD history, health challenges, meditation knowledge, and previous meditation practice. Barriers to meditation were evaluated using the Determinants of Meditation Practice Inventory (DMPI) and its revised version, DMPI-R. Overall frequencies, proportions, and measures of central tendency were calculated. Participants currently practicing meditation were compared to those not meditating by using Fisher's exact test, Student's t-test, and Wilcoxon rank-sum test.

Results

One hundred sixteen individuals completed the survey. Survey respondents were an average of 45 years (standard deviation, SD, 11.46), majority female (67.0 %), and White (90.3 %). Only 28.7 % of respondents were informed of meditation by their healthcare provider, yet 81.7 % were interested in learning about meditation. Among survey respondents, “prayer is my form of meditation,” followed by “I can't stop my thoughts,” were most agreed upon.

Conclusion

Individuals living with SUD are interested in education on meditation techniques; however, additional research is needed to understand the determinants of meditation practice and discern the barriers that could help facilitate the adoption and long-term practice of this method.
背景和目的患有物质使用障碍(SUD)的个体经常面临独特的挑战,这些挑战可能会阻碍他们参与冥想等有益的练习,而冥想已被证明有助于恢复和幸福。本研究旨在探索使用SUD进行冥想的感知障碍,确定主要障碍,并为未来的干预措施提供信息,以促进个人实践的采用。材料和方法我们对在SUD治疗中心就诊的参与者进行了一项横断面分析研究。收集的数据包括人口统计、SUD病史、健康挑战、冥想知识和以前的冥想练习。冥想障碍的评估采用冥想练习量表(DMPI)及其修订版DMPI- r。计算了总体频率、比例和集中趋势的度量。通过Fisher精确检验、学生t检验和Wilcoxon秩和检验,将正在进行冥想的参与者与未进行冥想的参与者进行比较。结果116人完成了调查。调查对象平均年龄45岁(标准差,SD, 11.46),以女性(67.0%)和白人(90.3%)居多。只有28.7%的受访者被他们的医疗保健提供者告知冥想,但81.7%的受访者有兴趣学习冥想。在调查对象中,“祈祷是我的冥想方式”,其次是“我无法停止我的想法”,这是最受欢迎的。结论:患有SUD的个体对冥想技术教育有兴趣;然而,需要更多的研究来了解冥想练习的决定因素,并辨别有助于促进这种方法的采用和长期练习的障碍。
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引用次数: 0
Effect of traditional Chinese fitness exercises on bone mineral density of middle-aged and elderly people–A systematic review and network meta-analysis 中国传统健身运动对中老年人骨密度的影响:系统综述和网络meta分析
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-23 DOI: 10.1016/j.ctcp.2025.101956
Zhuping Ren , Liyue He , Xiaoran Li , Lingxiang Yan , Zhuying Ren , Xiaolei Liu

Objective

To conduct a systematic review and network meta-analysis on the effects of traditional Chinese fitness exercises on bone mineral density (BMD) among middle-aged and elderly individuals.

Methods

Randomized controlled trials were collected from seven electronic databases: PubMed, EMBASE, Web of Science, the Cochrane Library, CNKI, VIP, and Wan fang. Studies were selected according to the PICOS principles. Totally 27, 28, 12 and 16 studies pertaining to lumbar spine BMD, femoral neck BMD, greater trochanter BMD, and Ward's triangle BMD, respectively, were comprehensively collected. The effectiveness of various exercise interventions was compared via network meta-analysis using the surface under the cumulative ranking area (SUCRA) to rank effectiveness.

Results

Thirty one studies were included in the risk assessment and network meta-analysis. In the network diagrams formed by the four BMD outcome measures, closed loops were identified within sequences Ba DuanJin, Yi JinJing, and CON; sequences Ba DuanJin, Wu QinXi, and CON; sequences Yi JinJing, Wu QinXi, and CON, allowing for direct and indirect comparisons. Tai Chi, Ba DuanJin, Yi JinJing, and Wu QinXi affected BMD in varying ways. As for lumbar spine BMD, the effect of Yi JinJing was ranked first (SUCRA = 69.3 %), followed by Wu QinXi (SUCRA = 66.7 %). In femoral neck BMD, Ba DuanJin was most the effective (SUCRA = 64.9 %). Tai Chi was ranked the highest in both greater trochanter BMD (SUCRA = 66.7 %) and Ward's triangle BMD (SUCRA = 61.6 %). Inconsistency assessment showed high reliability.

Conclusion

Traditional Chinese exercises may provide safe and feasible interventions for improving BMD in middle-aged and elderly people. Although there are no significant differences among most interventions, the SUCRA rankings suggest each exercise has potential advantages in different areas, providing a reference for personalized bone health management.
目的对中国传统健身运动对中老年人群骨密度的影响进行系统评价和网络meta分析。方法随机对照试验数据来源于PubMed、EMBASE、Web of Science、Cochrane Library、CNKI、VIP、万方等7个电子数据库。根据PICOS原则选择研究。综合收集腰椎骨密度、股骨颈骨密度、大转子骨密度和Ward三角区骨密度的研究分别为27、28、12和16项。通过网络荟萃分析,采用累积排名区域(SUCRA)下的表面对各种运动干预措施的有效性进行排名。结果31项研究纳入风险评估和网络荟萃分析。在四种BMD结果测量形成的网络图中,Ba端金、Yi JinJing和CON序列之间存在闭环;序列巴端金、吴钦喜、CON;序列易金晶,吴钦喜,和CON,允许直接和间接比较。太极拳、八段锦、易金经和武钦玺以不同的方式影响骨密度。腰椎骨密度方面,益金晶疗效最高(SUCRA = 69.3%),其次为吴钦喜(SUCRA = 66.7%)。在股骨颈骨密度方面,八段锦最有效(SUCRA = 64.9%)。太极拳在大转子骨密度(SUCRA = 66.7%)和沃德三角骨密度(SUCRA = 61.6%)方面排名最高。不一致性评估具有较高的信度。结论中医运动是改善中老年人骨密度的一种安全可行的干预措施。尽管大多数干预措施之间没有显着差异,但SUCRA排名表明每种运动在不同领域具有潜在优势,为个性化骨骼健康管理提供参考。
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引用次数: 0
“I am not pain, I have pain”: A pilot study examining iRest yoga nidra as a mind-body intervention for persistent pain “我不是疼痛,我有疼痛”:一项初步研究,研究了iRest瑜伽内德拉作为一种身心干预治疗持续疼痛的方法。
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-19 DOI: 10.1016/j.ctcp.2025.101955
Meg Barber , Subhadra Evans , Rosie Marks , Jo Sheedy , Richard Miller , Stephanie Lopez , Melissa O'Shea

Purpose

This pilot study was the first of its kind to examine the experiences of people with persistent pain engaging in a six-week iRest for Pain group program as part of multidisciplinary pain care.

Method

The present study used a qualitative, phenomenological design and reflexive thematic analysis to gain an understanding of the firsthand experience of patients who participated in the iRest for Pain group program. This program was offered in a specialist outpatient pain management service within a regional public hospital in Victoria, Australia.

Results

Participants reported they experienced iRest Yoga Nidra as personal and therapeutic, that the practice facilitated deep relaxation and restoration; for some participants trauma reprocessing and integration; improved pain self-management and self-efficacy, as well as dis-identification from persisting pain as personal identity. Additionally, some participants reported motivation and confidence to use iRest instead of medication, to reduce dependence on opioid medications.

Conclusion

The iRest for Pain group program presents a personally therapeutic and innovative mind-body intervention, which could be offered at various phases from primary to tertiary specialised pain care.
目的:本初步研究是同类研究中首次对持续疼痛患者进行为期六周的休息治疗,作为多学科疼痛治疗的一部分。方法:本研究采用定性、现象学设计和反身性主题分析来了解参加iRest治疗疼痛小组项目的患者的第一手经验。该项目是在澳大利亚维多利亚州的一家地区公立医院的专科门诊疼痛管理服务中提供的。结果:参与者报告说,他们体验了休息瑜伽内德拉作为个人和治疗,这种做法有助于深度放松和恢复;对于一些参与者创伤再加工和整合;改善疼痛自我管理和自我效能,以及不再将持续疼痛视为个人身份。此外,一些参与者报告了使用iRest代替药物的动机和信心,以减少对阿片类药物的依赖。结论:iRest for Pain小组项目提供了一种个人治疗和创新的身心干预,可以在初级到三级专业疼痛护理的各个阶段提供。
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引用次数: 0
Recreational older ballet dancers adapt faster to repeated standing-slips than older non-dancers 年龄较大的休闲芭蕾舞者比年龄较大的非舞蹈者更快地适应重复的站立滑倒。
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-18 DOI: 10.1016/j.ctcp.2025.101950
Caroline Simpkins, Feng Yang

Background

Falls are a global health concern facing older adults. Ballet emphasizes postural control, coordination, and leg muscle strength. Previous work indicated young professional ballet dancers adapt more effectively to repeated standing-slips than non-dancers as evidenced by better reactive improvements in dynamic gait stability and step latency. However, it remains unknown if older ballet dancers would show a quicker motor learning process than non-dancers. This study tested how older recreational ballet dancers adapt to five repeated standing-slip perturbations compared to non-dancers.

Materials and methods

Twenty older recreational dancers and 23 age- and sex-matched non-dancers experienced five unexpected slips while standing on a treadmill. The primary outcome was the slip-faller rate. Secondary outcomes included the percent change from first to last slip in kinematic measurements: dynamic gait stability, recovery stepping (step latency, duration, length), and trunk angle.

Results

Dancers showed a faster reduction in the slip-faller rate from the first to last standing-slip compared to the non-dancers (p = 0.004). The dancers improved dynamic gait stability at the recovery step touchdown more than the non-dancers (p = 0.002). The dancers increased their step duration (p = 0.006) more than the non-dancers across the five standing-slips, and dancers exhibited better improvement in trunk angle at recovery touchdown (p = 0.028).

Conclusions

Older ballet dancers adapt faster to repeated standing-slips and can improve their slip-faller rate more quickly compared to non-dancers. Dancers also improve their step duration and trunk angle as related to balance loss recovery, which may be attributed to their ballet practice.
背景:跌倒是老年人面临的全球性健康问题。芭蕾强调姿势控制、协调和腿部肌肉力量。先前的研究表明,年轻的专业芭蕾舞演员比不跳舞的人更能有效地适应反复的站立滑倒,这一点在动态步态稳定性和步骤延迟方面得到了更好的反应性改善。然而,年龄较大的芭蕾舞者是否会比不跳舞的人表现出更快的运动学习过程尚不清楚。这项研究测试了年龄较大的休闲芭蕾舞者与非舞蹈者相比如何适应五次重复的站滑扰动。材料和方法:20名年龄较大的休闲舞者和23名年龄和性别匹配的非舞者在站在跑步机上时经历了五次意外的滑倒。主要结果是失速下降率。次要结果包括运动学测量从第一次到最后一次滑动的百分比变化:动态步态稳定性,恢复步(步延迟,持续时间,长度)和躯干角度。结果:与不跳舞的人相比,跳舞的人从第一次到最后一次站立滑倒的速度下降得更快(p = 0.004)。在恢复步着地时,跳舞者比非跳舞者更能改善动态步态稳定性(p = 0.002)。在5次站立滑倒中,跳舞者的步长比不跳舞者增加得多(p = 0.006),在恢复触地时,跳舞者的躯干角度改善得更好(p = 0.028)。结论:与非芭蕾舞者相比,年龄较大的芭蕾舞者能够更快地适应重复的站立滑倒,并且能够更快地提高他们的滑倒率。舞者也提高了他们的步伐持续时间和躯干角度,这与平衡丧失恢复有关,这可能归因于他们的芭蕾舞练习。
{"title":"Recreational older ballet dancers adapt faster to repeated standing-slips than older non-dancers","authors":"Caroline Simpkins,&nbsp;Feng Yang","doi":"10.1016/j.ctcp.2025.101950","DOIUrl":"10.1016/j.ctcp.2025.101950","url":null,"abstract":"<div><h3>Background</h3><div>Falls are a global health concern facing older adults. Ballet emphasizes postural control, coordination, and leg muscle strength. Previous work indicated young professional ballet dancers adapt more effectively to repeated standing-slips than non-dancers as evidenced by better reactive improvements in dynamic gait stability and step latency. However, it remains unknown if older ballet dancers would show a quicker motor learning process than non-dancers. This study tested how older recreational ballet dancers adapt to five repeated standing-slip perturbations compared to non-dancers.</div></div><div><h3>Materials and methods</h3><div>Twenty older recreational dancers and 23 age- and sex-matched non-dancers experienced five unexpected slips while standing on a treadmill. The primary outcome was the slip-faller rate. Secondary outcomes included the percent change from first to last slip in kinematic measurements: dynamic gait stability, recovery stepping (step latency, duration, length), and trunk angle.</div></div><div><h3>Results</h3><div>Dancers showed a faster reduction in the slip-faller rate from the first to last standing-slip compared to the non-dancers (<em>p</em> = 0.004). The dancers improved dynamic gait stability at the recovery step touchdown more than the non-dancers (<em>p</em> = 0.002). The dancers increased their step duration (<em>p</em> = 0.006) more than the non-dancers across the five standing-slips, and dancers exhibited better improvement in trunk angle at recovery touchdown (<em>p</em> = 0.028).</div></div><div><h3>Conclusions</h3><div>Older ballet dancers adapt faster to repeated standing-slips and can improve their slip-faller rate more quickly compared to non-dancers. Dancers also improve their step duration and trunk angle as related to balance loss recovery, which may be attributed to their ballet practice.</div></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"59 ","pages":"Article 101950"},"PeriodicalIF":2.2,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between trait mindfulness and physical activity among emerging adults: The mediating roles of exercise-related cognitive errors and trait self-control 初出期成人特质正念与身体活动的关系:运动相关认知错误和特质自我控制的中介作用
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-18 DOI: 10.1016/j.ctcp.2025.101953
Ding Yuan , Jin Kuang , Jinming Li , Rebecca Y.M. Cheung , Fabian Herold , Markus Gerber , Alyx Taylor , Arthur F. Kramer , Jiahui Wang , Albert S. Yeung , Liye Zou

Objective

Exercise-related cognitive errors (ECEs) is a significant factor that can negatively influence physical activity (PA) engagement among emerging adults, whereas mindfulness interventions may be beneficial for promoting PA. Against this background, we investigated the potential association between trait mindfulness and PA levels among emerging adults and determined whether trait self-control and ECEs serve as mediators.

Method

328 Chinese participants (61.3 % female, mean age = 20.65, SD = 2.21) completed a series of questionnaires, including demographics, the Five Dimension Mindfulness Questionnaire short form (FFMQ-SF), the Exercise Cognitive Bias Questionnaire (E-CEQ), the Brief Self Control Scale (BSCS), and the short form of the International Physical Activity Questionnaire (IPAQ-SF). A structural equation model was used to investigate the potential relationships between trait mindfulness and PA levels, considering trait self-control and ECEs as mediators.

Results

Trait self-control (Indirect 1; B = 0.09, 95%CI: 0.04, 0.16) and ECEs (Indirect 3; B = 0.02, 95%CI: 0.00, 0.04) mediates the relationship between trait mindfulness and PA levels, respectively, when considered as independent mediators. In addition, also in a dual-mediation model ECEs and trait self-control (Indirect 2; B = 0.02, 95%CI [0.00, 0.06]) mediate the relationship between trait mindfulness and PA.

Conclusions

This study provides evidence that trait self-control and ECEs are mediators of the relationship between trait mindfulness and PA levels, providing a new direction for further research aiming to reduce ECEs and improve PA levels among emerging adults.
目的:运动相关认知错误(ECEs)是影响初出期成人身体活动(PA)参与的一个重要因素,而正念干预可能有利于促进PA。在此背景下,我们调查了新兴成人特质正念和PA水平之间的潜在关联,并确定特质自我控制和ECEs是否起到中介作用。方法:328名中国参与者(女性占61.3%,平均年龄20.65岁,SD = 2.21)完成了包括人口统计学、五维度正念问卷简式(FFMQ-SF)、运动认知偏差问卷(E-CEQ)、简易自我控制量表(BSCS)和国际体育活动问卷简式(IPAQ-SF)在内的一系列问卷调查。本研究采用结构方程模型考察特质正念与PA水平之间的潜在关系,并考虑特质自我控制和ece作为中介。结果:特质自我控制(间接1;B = 0.09, 95%CI: 0.04, 0.16)和ECEs(间接3;当B = 0.02, 95%CI: 0.00, 0.04)作为独立中介因子时,分别介导特质正念和PA水平之间的关系。此外,在双重中介模型中,个体行为干预与特质自我控制(Indirect 2;B = 0.02, 95%CI[0.00, 0.06])在特质正念与PA的关系中起中介作用。结论:本研究提供了特质自我控制和ece是特质正念与PA水平之间关系的中介,为进一步研究减少初生成人的ece和提高PA水平提供了新的方向。
{"title":"Relationship between trait mindfulness and physical activity among emerging adults: The mediating roles of exercise-related cognitive errors and trait self-control","authors":"Ding Yuan ,&nbsp;Jin Kuang ,&nbsp;Jinming Li ,&nbsp;Rebecca Y.M. Cheung ,&nbsp;Fabian Herold ,&nbsp;Markus Gerber ,&nbsp;Alyx Taylor ,&nbsp;Arthur F. Kramer ,&nbsp;Jiahui Wang ,&nbsp;Albert S. Yeung ,&nbsp;Liye Zou","doi":"10.1016/j.ctcp.2025.101953","DOIUrl":"10.1016/j.ctcp.2025.101953","url":null,"abstract":"<div><h3>Objective</h3><div>Exercise-related cognitive errors (ECEs) is a significant factor that can negatively influence physical activity (PA) engagement among emerging adults, whereas mindfulness interventions may be beneficial for promoting PA. Against this background, we investigated the potential association between trait mindfulness and PA levels among emerging adults and determined whether trait self-control and ECEs serve as mediators.</div></div><div><h3>Method</h3><div>328 Chinese participants (61.3 % female, mean age = 20.65, SD = 2.21) completed a series of questionnaires, including demographics, the Five Dimension Mindfulness Questionnaire short form (FFMQ-SF), the Exercise Cognitive Bias Questionnaire (E-CEQ), the Brief Self Control Scale (BSCS), and the short form of the International Physical Activity Questionnaire (IPAQ-SF). A structural equation model was used to investigate the potential relationships between trait mindfulness and PA levels, considering trait self-control and ECEs as mediators.</div></div><div><h3>Results</h3><div>Trait self-control (Indirect 1; B = 0.09, 95%CI: 0.04, 0.16) and ECEs (Indirect 3; B = 0.02, 95%CI: 0.00, 0.04) mediates the relationship between trait mindfulness and PA levels, respectively, when considered as independent mediators. In addition, also in a dual-mediation model ECEs and trait self-control (Indirect 2; B = 0.02, 95%CI [0.00, 0.06]) mediate the relationship between trait mindfulness and PA.</div></div><div><h3>Conclusions</h3><div>This study provides evidence that trait self-control and ECEs are mediators of the relationship between trait mindfulness and PA levels, providing a new direction for further research aiming to reduce ECEs and improve PA levels among emerging adults.</div></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"59 ","pages":"Article 101953"},"PeriodicalIF":2.2,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of different probiotic regimens for allergic rhinitis: A network meta-analysis 不同益生菌治疗变应性鼻炎的疗效:网络荟萃分析。
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-16 DOI: 10.1016/j.ctcp.2025.101954
Chang Lu , Yuan Gao , Siyue Dong , Yaoyao Sun , Mingjuan Sun , Xinle Han , Bo Li , Changyi Li , Yajun Zhang , Minhui Li

Background

To evaluate the efficacy of different probiotic species in the treatment of Allergic rhinitis (AR), we used network meta-analysis (NMA), which provides a foundation for evidence-based therapeutic selection.

Methods

Nine databases were searched from their inception until April 30, 2024. Stata 17.0 and Review Manager 5.4 were used to conduct the NMA. The main outcomes included total nasal symptom score (TNSS), Rhinitis Quality of Life (RQLQ) global scores, total and specific IgE levels, blood eosinophil count, efficacy rate, and adverse events.

Results

31 randomized controlled trials (RCTs) were included, involving 2544 patients with AR. In the NMA, in terms of reducing TNSS: Saccharomyces > Mix > Bifidobacterium > Enterococcus faecalis > Lactobacillus > Bacillus > conventional therapy; in terms of reducing RQLQ: Mix > Lactobacillus > Enterococcus faecalis > conventional therapy; in terms of reducing Total IgE: Mix > Bifidobacterium > Lactobacillus > Tetragenococcus halophilus > conventional therapy; in terms of reducing Special IgE: Mix > conventional therapy > Bifidobacterium > Lactobacillus > Leuconostoc; in terms of reducing blood eosinophil count: Lactobacillus > conventional therapy > Mix; in terms of improving the efficacy rate: Saccharomyces > Mix > conventional therapy. No serious adverse events were reported regarding safety.

Conclusion

Probiotic mixtures may be the most effective in reducing RQLQ, Total IgE, and Special IgE; Saccharomyces may be the most efficacious in reducing TNSS and improving the efficacy rate; and Lactobacillus may be the most effective in reducing blood eosinophil count. Overall, probiotic mixtures demonstrated better combined efficacy.
背景:为了评价不同益生菌种类治疗变应性鼻炎(AR)的疗效,我们采用网络meta分析(NMA)方法,为循证治疗选择提供依据。方法:检索自建库至2024年4月30日的9个数据库。采用Stata 17.0和Review Manager 5.4进行NMA。主要结局包括鼻症状总评分(TNSS)、鼻炎生活质量(RQLQ)总体评分、总IgE和特异性IgE水平、血嗜酸性粒细胞计数、有效率和不良事件。结果:纳入31项随机对照试验(RCTs),共纳入2544例AR患者。在NMA中,在降低TNSS方面:Saccharomyces > Mix > Bifidobacterium > Enterococcus faecalis > Lactobacillus > Bacillus >常规治疗;在降低RQLQ方面:混合>乳杆菌>粪肠球菌>常规疗法;在降低总IgE方面:混合>双歧杆菌>乳杆菌>嗜盐四芽球菌>常规疗法;在降低特殊IgE方面:混合>常规疗法>双歧杆菌>乳酸菌>白菌;在降低血嗜酸性粒细胞计数方面:乳酸菌>常规疗法>混合;在提高有效率方面:酵母>混合>常规疗法。在安全性方面没有严重的不良事件报告。结论:混合益生菌降低RQLQ、总IgE和特殊IgE的效果最好;在降低TNSS和提高效率方面,酵母菌可能是最有效的;乳酸杆菌可能是减少血液嗜酸性粒细胞计数最有效的。总体而言,益生菌混合物显示出更好的联合功效。
{"title":"Efficacy of different probiotic regimens for allergic rhinitis: A network meta-analysis","authors":"Chang Lu ,&nbsp;Yuan Gao ,&nbsp;Siyue Dong ,&nbsp;Yaoyao Sun ,&nbsp;Mingjuan Sun ,&nbsp;Xinle Han ,&nbsp;Bo Li ,&nbsp;Changyi Li ,&nbsp;Yajun Zhang ,&nbsp;Minhui Li","doi":"10.1016/j.ctcp.2025.101954","DOIUrl":"10.1016/j.ctcp.2025.101954","url":null,"abstract":"<div><h3>Background</h3><div>To evaluate the efficacy of different probiotic species in the treatment of Allergic rhinitis (AR), we used network meta-analysis (NMA), which provides a foundation for evidence-based therapeutic selection.</div></div><div><h3>Methods</h3><div>Nine databases were searched from their inception until April 30, 2024. Stata 17.0 and Review Manager 5.4 were used to conduct the NMA. The main outcomes included total nasal symptom score (TNSS), Rhinitis Quality of Life (RQLQ) global scores, total and specific IgE levels, blood eosinophil count, efficacy rate, and adverse events.</div></div><div><h3>Results</h3><div>31 randomized controlled trials (RCTs) were included, involving 2544 patients with AR. In the NMA, in terms of reducing TNSS: Saccharomyces &gt; Mix &gt; Bifidobacterium &gt; <em>Enterococcus faecalis</em> &gt; Lactobacillus &gt; Bacillus &gt; conventional therapy; in terms of reducing RQLQ: Mix &gt; Lactobacillus &gt; <em>Enterococcus faecalis</em> &gt; conventional therapy; in terms of reducing Total IgE: Mix &gt; Bifidobacterium &gt; Lactobacillus &gt; Tetragenococcus halophilus &gt; conventional therapy; in terms of reducing Special IgE: Mix &gt; conventional therapy &gt; Bifidobacterium &gt; Lactobacillus &gt; Leuconostoc; in terms of reducing blood eosinophil count: Lactobacillus &gt; conventional therapy &gt; Mix; in terms of improving the efficacy rate: Saccharomyces &gt; Mix &gt; conventional therapy. No serious adverse events were reported regarding safety.</div></div><div><h3>Conclusion</h3><div>Probiotic mixtures may be the most effective in reducing RQLQ, Total IgE, and Special IgE; Saccharomyces may be the most efficacious in reducing TNSS and improving the efficacy rate; and Lactobacillus may be the most effective in reducing blood eosinophil count. Overall, probiotic mixtures demonstrated better combined efficacy.</div></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"59 ","pages":"Article 101954"},"PeriodicalIF":2.2,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic effects of dry needling for patellofemoral pain syndrome: a systematic review and meta-analysis 干针治疗髌骨痛综合征的疗效:一项系统综述和荟萃分析。
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-16 DOI: 10.1016/j.ctcp.2025.101938
Zilin Sun, Renyi Liu

Background and purpose

Dry needling has been increasingly used as an adjunctive therapy for patellofemoral pain syndrome in clinical practice. This study aimed to summarize the available evidence about the effects of dry needling in managing patellofemoral pain syndrome.

Methods

Seven English-language databases and three Chinese-language databases were searched. Two researchers independently screened the literature, extracted data, and assessed the risk of bias using the PEDro scale and the Cochrane Risk of Bias Assessment Tool. The quality of evidence was evaluated using the GRADE approach.

Results

A total of 12 studies were included, involving 624 participants. Dry needling significantly improved knee pain (MD = −0.86, 95%CI -1.17 to −0.55) and physical function (MD = 5.33, 95%CI 3.88 to 6.78) compared to comparative groups. When combined with exercise therapy, dry needling resulted in large reduction in knee pain(MD = −2.02, 95%CI -2.36 to −1.67) and small improvement in physical function (MD = 9.56, 95%CI 7.84 to 11.27) compared to exercise therapy alone. However, negligible or no additional benefits were observed when dry needling was added to extracorporeal shock wave therapy or multimodal interventions. Furthermore, dry needling showed no significant advantage over other trigger point therapies in terms of pain reduction and functional improvement.

Conclusion

Dry needling is effective in reducing pain and improving function for patients with patellofemoral pain syndrome, particularly when combined with exercise therapy. However, more high-quality studies are required to draw a definitive conclusion.

Clinical trial registration number

CRD42023490627 on PROSPERO.
背景与目的:临床上越来越多地使用干针作为髌股痛综合征的辅助治疗方法。本研究旨在总结有关干针治疗髌股疼痛综合征的现有证据。方法:检索7个英文数据库和3个中文数据库。两名研究人员独立筛选文献,提取数据,并使用PEDro量表和Cochrane偏倚风险评估工具评估偏倚风险。使用GRADE方法评估证据质量。结果:共纳入12项研究,624名受试者。与对照组相比,干针明显改善了膝关节疼痛(MD = -0.86, 95%CI -1.17 ~ -0.55)和身体功能(MD = 5.33, 95%CI 3.88 ~ 6.78)。当与运动疗法联合使用时,与单独运动疗法相比,干针疗法可显著减轻膝关节疼痛(MD = -2.02, 95%CI -2.36至-1.67),并可轻微改善身体功能(MD = 9.56, 95%CI 7.84至11.27)。然而,当干针加入体外冲击波治疗或多模式干预时,可忽略或没有观察到额外的益处。此外,在减轻疼痛和功能改善方面,干针疗法与其他触发点疗法相比没有明显的优势。结论:干针治疗髌骨股痛综合征能有效减轻疼痛,改善功能,特别是与运动疗法相结合。然而,要得出明确的结论,还需要更多高质量的研究。临床试验注册号:CRD42023490627。
{"title":"Therapeutic effects of dry needling for patellofemoral pain syndrome: a systematic review and meta-analysis","authors":"Zilin Sun,&nbsp;Renyi Liu","doi":"10.1016/j.ctcp.2025.101938","DOIUrl":"10.1016/j.ctcp.2025.101938","url":null,"abstract":"<div><h3>Background and purpose</h3><div>Dry needling has been increasingly used as an adjunctive therapy for patellofemoral pain syndrome in clinical practice. This study aimed to summarize the available evidence about the effects of dry needling in managing patellofemoral pain syndrome.</div></div><div><h3>Methods</h3><div>Seven English-language databases and three Chinese-language databases were searched. Two researchers independently screened the literature, extracted data, and assessed the risk of bias using the PEDro scale and the Cochrane Risk of Bias Assessment Tool. The quality of evidence was evaluated using the GRADE approach.</div></div><div><h3>Results</h3><div>A total of 12 studies were included, involving 624 participants. Dry needling significantly improved knee pain (MD = −0.86, 95%CI -1.17 to −0.55) and physical function (MD = 5.33, 95%CI 3.88 to 6.78) compared to comparative groups. When combined with exercise therapy, dry needling resulted in large reduction in knee pain(MD = −2.02, 95%CI -2.36 to −1.67) and small improvement in physical function (MD = 9.56, 95%CI 7.84 to 11.27) compared to exercise therapy alone. However, negligible or no additional benefits were observed when dry needling was added to extracorporeal shock wave therapy or multimodal interventions. Furthermore, dry needling showed no significant advantage over other trigger point therapies in terms of pain reduction and functional improvement.</div></div><div><h3>Conclusion</h3><div>Dry needling is effective in reducing pain and improving function for patients with patellofemoral pain syndrome, particularly when combined with exercise therapy. However, more high-quality studies are required to draw a definitive conclusion.</div></div><div><h3>Clinical trial registration number</h3><div>CRD42023490627 on PROSPERO.</div></div>","PeriodicalId":48752,"journal":{"name":"Complementary Therapies in Clinical Practice","volume":"59 ","pages":"Article 101938"},"PeriodicalIF":2.2,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare professionals’ attitudes to animal assisted activity with dogs in paediatric care 医疗保健专业人员对动物辅助活动与狗在儿科护理的态度。
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-15 DOI: 10.1016/j.ctcp.2025.101952
M. Lindstrom Nilsson, K. Enskar, G. Engvall, A. Edner, E.-L. Funkquist

Background

Hospitalization for children often involves stress induced by fear and pain. Complementary therapies, such as Animal Assisted Activities (AAA) with dogs, can alleviate the hospital experience.

Purpose

The first aim of this study was to initiate the development of an instrument that measures healthcare professionals’ attitudes toward complementary therapy, specifically dogs in AAA. The second aim was to elucidate the emerging effects of introducing dogs to children in healthcare settings, as reported by healthcare professionals.

Materials and methods

A questionnaire covering demographics, rating attitudes, and allergy and hygiene risks, followed by open-ended questions, was completed by 61 healthcare professionals (HCPs). Quantitative data were analysed statistically, while qualitative data underwent content analysis.

Results

The Attitude Instrument of Complementary Therapy (AICT) included 7 items and was evaluated using exploratory factor analysis. Healthcare professionals had a median score of 25 (range 18–28), high scores indicating a more positive attitude. However, 36 % of the HCPs perceived a risk of allergies, and this group had a significantly lower median score, 22 versus 26. Open-ended answers were analysed into four categories: “Dogs could positively affect children in hospital”, “Dogs may pose a risk of allergies in children”, “Dogs might be frightening for children” and “Dogs can affect healthcare professionals’ working situation”.

Conclusion

The AICT can serve as a valuable tool for investigating HCPs’ attitudes to dogs in AAA as complementary therapies. Professionals view dogs as beneficial for hospitalized children, but attitudes toward dogs working in paediatric care can be influenced by concerns about risks such as allergies.
背景:儿童住院往往涉及由恐惧和疼痛引起的压力。辅助疗法,如动物辅助活动(AAA)与狗,可以减轻医院的经验。目的:本研究的第一个目的是开发一种测量医疗保健专业人员对补充治疗的态度的工具,特别是AAA中的狗。第二个目的是阐明医疗保健专业人员报告的在医疗保健环境中向儿童介绍狗的新效果。材料和方法:61名卫生保健专业人员(HCPs)完成了一份涵盖人口统计学、评价态度、过敏和卫生风险的问卷调查,随后是开放式问题。定量资料进行统计分析,定性资料进行内容分析。结果:辅助治疗态度量表(AICT)包括7个项目,采用探索性因素分析进行评价。医疗保健专业人员的平均得分为25分(范围在18-28之间),得分越高表明态度越积极。然而,36%的HCPs认为有过敏风险,这一组的中位数得分明显较低,为22比26。开放式回答被分析为四类:“狗可能对住院儿童产生积极影响”、“狗可能会对儿童造成过敏风险”、“狗可能会让儿童感到害怕”和“狗可能会影响医护人员的工作环境”。结论:AICT可以作为一种有价值的工具,用于调查AAA患者医护人员对狗的态度。专业人士认为,养狗对住院儿童有益,但对儿科护理中养狗的态度可能会受到过敏等风险的影响。
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引用次数: 0
Efficacy and safety of olive leaf extract (Olea europaea L.) for glycaemic control in adults with type 2 diabetes mellitus (ESOLED): A pilot randomised controlled trial 橄榄叶提取物(Olea europaea L.)对成人2型糖尿病(ESOLED)血糖控制的有效性和安全性:一项随机对照试验
IF 2.2 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2025-01-13 DOI: 10.1016/j.ctcp.2025.101949
Matthew J. Leach , Ian Breakspear

Background

Maintaining optimum glycaemic control is essential to reducing comorbidity and mortality in diabetes. However, research indicates that <50 % of patients achieve their target HbA1c ranges. Laboratory studies suggest that olive leaf extract (OLE) may improve glycaemic control, however clinical studies in persons with diabetes are lacking.

Methods

ESOLED is a pilot, randomised, placebo-controlled trial. Adults with a diagnosis of type 2 diabetes of ≥12 months duration, and not receiving insulin therapy, were eligible to participate. Participants were randomised to receive OLE or placebo capsules for 24 weeks. The primary outcome was change in HbA1c. Secondary outcomes included changes in the homeostasis model assessment of insulin resistance, diabetes-related stress, health-related quality of life, and safety.

Results

Thirty-one participants were randomly assigned to the OLE (n = 16) and placebo (n = 15) groups. Analyses found no statistically significant time-group interactions for HbA1c, diabetes-related distress or health-related quality of life. Although participants receiving OLE demonstrated greater improvements in insulin sensitivity than those on placebo, there was no significant difference between groups over time. OLE and placebo were found to be well-tolerated, with no severe or serious adverse events reported in either group.

Conclusion

The ESOLED trial has provided preliminary evidence on the tolerability of OLE in adults with type 2 diabetes, but was inconclusive in determining whether OLE is effective at improving glycaemic control, insulin sensitivity, diabetes-related distress and quality of life. Larger trials and further exploration of the bioavailability of OLE are needed to fully assess the therapeutic potential of OLE in diabetes.

Trial registration

Australian New Zealand Clinical Trials Registry (ACTRN12622000616774).
背景:维持最佳血糖控制对于减少糖尿病的合并症和死亡率至关重要。然而,研究表明,方法:ESOLED是一个试点,随机,安慰剂对照试验。诊断为2型糖尿病且持续时间≥12个月且未接受胰岛素治疗的成年人符合参与条件。参与者随机接受OLE或安慰剂胶囊24周。主要终点是HbA1c的变化。次要结局包括胰岛素抵抗、糖尿病相关压力、健康相关生活质量和安全性的动态平衡模型评估的变化。结果:31名参与者被随机分配到OLE组(n = 16)和安慰剂组(n = 15)。分析发现,在HbA1c、糖尿病相关痛苦或与健康相关的生活质量方面,没有统计学上显著的时间组相互作用。虽然接受OLE治疗的参与者在胰岛素敏感性方面比安慰剂组有更大的改善,但随着时间的推移,两组之间没有显著差异。发现OLE和安慰剂耐受性良好,两组均未报告严重或严重不良事件。结论:ESOLED试验为成人2型糖尿病患者OLE的耐受性提供了初步证据,但在确定OLE是否有效改善血糖控制、胰岛素敏感性、糖尿病相关窘迫和生活质量方面尚无定论。为了充分评估OLE在糖尿病中的治疗潜力,需要更大规模的试验和进一步探索OLE的生物利用度。试验注册:澳大利亚新西兰临床试验注册中心(ACTRN12622000616774)。
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引用次数: 0
期刊
Complementary Therapies in Clinical Practice
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