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Revista Portuguesa De Cardiologia最新文献

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Premature coronary artery disease primary prevention - Searching for the Holy Grail. 冠心病早期初级预防--寻找圣杯。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-01-01 Epub Date: 2024-11-15 DOI: 10.1016/j.repc.2024.11.002
Jorge Alcaravela
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引用次数: 0
Strategic Plan for Cardiovascular Health in Portugal - Portuguese Society of Cardiology (PESCP-SPC). 葡萄牙心血管健康战略计划——葡萄牙心脏病学会(PESCP-SPC)。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-01-01 Epub Date: 2024-11-30 DOI: 10.1016/j.repc.2024.11.006
Sofia Cabral, Cristina Gavina, Manuel Almeida, Alexandra Sousa, Ana Rita Francisco, Eduardo Infante Oliveira, Kevin Domingues, Luísa Moura Branco, Sílvia Monteiro, Sofia Alegria, Rui Baptista, Hélder Pereira

The Strategic Plan for Cardiovascular Health in Portugal is an initiative of the Portuguese Society of Cardiology, aligned with efforts by the European Society of Cardiology and the World Heart Federation to develop national plans, at a local level within the cultural and socio-economic contexts, focused on cardiovascular health. The overarching goal is to promote and ensure the continuous and sustained improvement of cardiovascular health in the Portuguese population. The methodology identified key challenges and opportunities for the medium term, highlighted priority areas for intervention, and proposed strategic lines of action. This article outlines the project's design and establishes a guiding framework for the proposed actions, which will be drawn up by designated expert groups and communicated subsequently.

葡萄牙心血管健康战略计划是葡萄牙心脏病学会的一项倡议,与欧洲心脏病学会和世界心脏联合会在文化和社会经济背景下制定地方一级以心血管健康为重点的国家计划的努力保持一致。总体目标是促进和确保葡萄牙人口心血管健康的持续和持续改善。该方法确定了中期的主要挑战和机会,突出了干预的优先领域,并提出了战略行动方针。本文概述了项目的设计,并为拟议的行动建立了指导框架,该框架将由指定的专家组起草并随后进行沟通。
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引用次数: 0
Non-invasive estimation of left ventricular filling pressures: In the absence of an "Holy Grail", a multiparametric integrative approach may be the key. 无创估测左心室充盈压:在缺乏 "圣杯 "的情况下,多参数综合方法可能是关键所在。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-01-01 Epub Date: 2024-11-17 DOI: 10.1016/j.repc.2024.11.001
Marisa Trabulo
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引用次数: 0
Investigation of the effect of intravitreal bevacizumab treatment on left heart function using speckle tracking echocardiography. 使用斑点追踪超声心动图研究玻璃体内贝伐单抗治疗对左心功能的影响。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-01-01 Epub Date: 2024-08-30 DOI: 10.1016/j.repc.2024.07.006
Mehmet Şahinbaş, İdris Buğra Çerik, Duygu Yalınbaş Yeter

Introduction and objectives: Vascular endothelial growth factor (VEGF) inhibitors are widely used in oncology and ophthalmology. Although these agents have been shown to increase the risk of cardiovascular events in systemic use, the effect of local applications is unclear. In our study, we aimed to investigate the effects of anti-VEGF agents on left heart functions after intravitreal injection using speckle tracking echocardiography.

Methods: In this prospectively designed study, 44 patients who were going to start intravitreal anti-VEGF treatment were included in the study. Patients were evaluated with speckle tracking echocardiography before the first anti-VEGF administration and at three months of anti-VEGF treatment.

Results: Global longitudinal strain (GLS) values at three months were lower in the patients who participated in the study and this was statistically significant (-18.77±2.17, -18.60±2.01, p=0.001). Also, there was a statistically significant decrease in the mean values of GLS (GLS4CH) obtained from apical four space image, GLS (GLSAPLAX) obtained from apical long axis image and GLS (GLS2CH) obtained from apical 2 space image at month 0 and month 3 (-19.08±2.39, -18.93±2.26, p=0.004; -18.81±2.29, -18.60±2.12, p=0.001; -18.44±2.31, -18.27±2.12, p=0.013, respectively).

Conclusion: The slight decrease in GLS in our study suggests that the use of intravitreal anti-VEGF agents may have cardiac effects.

导言和目标:血管内皮生长因子(VEGF)抑制剂广泛应用于肿瘤学和眼科学。虽然这些药物在全身使用时会增加心血管事件的风险,但局部应用的影响尚不清楚。在我们的研究中,我们旨在使用斑点追踪超声心动图研究抗血管内皮生长因子药物在玻璃体内注射后对左心功能的影响:在这项前瞻性设计的研究中,44 名即将开始接受玻璃体内抗血管内皮生长因子治疗的患者被纳入研究。患者在首次注射抗血管内皮生长因子前和接受抗血管内皮生长因子治疗三个月后接受斑点追踪超声心动图评估:结果:参与研究的患者三个月后的整体纵向应变(GLS)值较低,且具有统计学意义(-18.77±2.17,-18.60±2.01,P=0.001)。此外,在第 0 个月和第 3 个月,从根尖四间隙图像获得的 GLS(GLS4CH)、从根尖长轴图像获得的 GLS(GLSAPLAX)和从根尖二间隙图像获得的 GLS(GLS2CH)的平均值均有统计学意义的下降(-19.08±2.39,-18.93±2.26,p=0.004;-18.81±2.29,-18.60±2.12,p=0.001;-18.44±2.31,-18.27±2.12,p=0.013):本研究中 GLS 的轻微下降表明,使用玻璃体内抗 VEGF 药物可能会对心脏产生影响。
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引用次数: 0
Not an allergy: Iodine contrast-induced acute sialadenitis after coronary angiography. 不是过敏:冠状动脉造影术后碘造影剂诱发的急性浆膜炎。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-01-01 Epub Date: 2024-08-30 DOI: 10.1016/j.repc.2024.06.002
Victor Vallejo-Garcia, Óscar Fabregat-Andrés, Ana Lainez-Nuez
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引用次数: 0
Tuberculous submitral aneurysm: A rare cardiac presentation of a common pathogen. 结核性腹膜下动脉瘤:一种常见病原体的罕见心脏表现。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-01-01 Epub Date: 2024-06-19 DOI: 10.1016/j.repc.2024.03.002
Usnish Adhikari, Harikrishnan Sivadasanpillai, Bineesh K Radhakrishnan, Mohamed Iliyas
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引用次数: 0
Knowledge and perception of disease - time to empower the needy and change the world! 对疾病的认识和认知——是时候赋予有需要的人力量,改变世界了!
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-12-05 DOI: 10.1016/j.repc.2024.11.007
Rui Anjos
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引用次数: 0
The Ross procedure in aortic valve replacement: Long-term insights and future perspectives. 主动脉瓣置换术中的Ross手术:长期观察和未来展望。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-12-05 DOI: 10.1016/j.repc.2024.12.001
Sérgio Laranjo
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引用次数: 0
Beyond clinical trials – The cost saving associated with dapagliflozin use in Portugal hospital clinical practice 临床试验之外 - 在葡萄牙医院临床实践中使用达帕格列净可节省成本。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-12-01 DOI: 10.1016/j.repc.2024.04.012
Dulce Brito , Cândida Fonseca , Fátima Franco , Vanessa Lopes , Sara Gonçalves , Rui Baptista , Joana Sequeira , Irene Marques , Rita Rego , Joana Pimenta , José Silva-Cardoso , Margarida Lopes , Mário Almeida

Introduction and objectives

Heart failure (HF) is a clinical syndrome associated with substantial morbidity, mortality, and healthcare costs. Dapagliflozin has proven efficacy in reducing the risk of death and hospitalization in HF patients, regardless of left ventricular ejection fraction (LVEF). This paper aimed to project the potential impact of dapagliflozin on healthcare costs related to HF subsequent hospitalizations (HFHs) in Portuguese hospitals.

Methods

The total number of HF-related hospitalizations (hHF), HFHs, and the average length of stay for patients with a primary diagnosis of HF from six Portuguese hospitals, between January 2019 and December 2021, were collected and aggregated by hospital classification. Costs associated with HFHs were calculated according to Portuguese legislation and considering conservative, average, and complex approaches. Cost-saving projections were based on extrapolations from hHF risk reductions reported in dapagliflozin clinical trials.

Results

Considering a 26% risk reduction in hHF reported on pooled-analysis of DAPA-HF and DELIVER as the expected reduction in HFHs, the use of dapagliflozin would be associated with cost savings ranging from EUR 1 612 851.54 up to EUR 6 587 360.09, when considering all hospitals and the different approaches, between 2019 and 2021. A similar projection is observed based on 24% RRR derived by weighting DAPA-HF and DELIVER sub-analyses and PORTHOS epidemiological data.

Conclusions

In this projection, dapagliflozin use in all eligible hHF patients is associated with a significant reduction in direct costs. Our data support that, in addition to the improvements in HF-related outcomes, dapagliflozin may have a significant economic impact on healthcare costs in Portuguese hospitals.
导言和目标:心力衰竭(HF)是一种与大量发病率、死亡率和医疗成本相关的临床综合征。事实证明,无论左心室射血分数(LVEF)如何,达帕格列净都能有效降低心力衰竭患者的死亡和住院风险。本文旨在预测达帕格列净对葡萄牙医院与高血压后续住院(HFHs)相关的医疗费用的潜在影响:收集了2019年1月至2021年12月期间葡萄牙六家医院的HF相关住院总人数(hHF)、HFHs以及初诊为HF患者的平均住院时间,并按医院分类进行汇总。根据葡萄牙法律,并考虑到保守、平均和复杂方法,计算了与高频心房颤动相关的成本。成本节约预测基于达帕格列净临床试验中报告的高血压风险降低的推断:结果:如果将 DAPA-HF 和 DELIVER 的汇总分析所报告的 HFH 风险降低 26% 作为 HFHs 的预期降低率,那么考虑到所有医院和不同的方法,在 2019 年至 2021 年期间,使用达帕格列净可节约成本 1 612 851.54 欧元至 6 587 360.09 欧元不等。通过加权 DAPA-HF 和 DELIVER 子分析以及 PORTHOS 流行病学数据得出的 24% 的 RRR 也得出了类似的预测结果:在这一预测中,所有符合条件的 hHF 患者使用达帕格列净可显著降低直接费用。我们的数据证明,除了改善心房颤动相关预后外,达帕格列净还可能对葡萄牙医院的医疗成本产生重大经济影响。
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引用次数: 0
One more piece in the puzzle of stem cell therapy in cardiovascular diseases 干细胞治疗心血管疾病的拼图又多了一块。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-12-01 DOI: 10.1016/j.repc.2024.08.007
Rita Nogueira-Ferreira , Adelino F. Leite-Moreira
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引用次数: 0
期刊
Revista Portuguesa De Cardiologia
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