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Intraoperative Utilization of Intravenous Methadone for Postoperative Pain Control 术中静脉美沙酮在术后疼痛控制中的应用。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jopan.2025.03.007
Daniela Laguado BSN, RN , Jiale Hu PhD, RN, FAAN , Chad Watkins PharmD, MHA , James Furstein PhD, DNAP, CRNA, CPNP-AC, FAANA

Purpose

Postoperative pain is a unique experience that can be challenging to manage. It is imperative that perioperative nursing staff have a sound understanding of a multitude of pharmacological interventions. When compared to other intraoperative opioids, intravenous methadone has not been widely researched as a tool for the prevention of postoperative pain. The purpose of this systematic review is to provide evidence for its use and efficacy in preventing postoperative pain.

Design

Systematic review.

Methods

This review used a broad research strategy to seek out relevant publications from the last decade (2014 to January 2024). The databases used included MEDLINE (PubMed) and Google Scholar. Out of the initial 129 studies identified, 7 relevant clinical trials, 2 retrospective reviews, and 1 systematic review were chosen based on the inclusion criteria.

Findings

Patients who received adequate doses of intraoperative methadone, defined as doses between 0.1 and 0.4 mg/kg ideal body weight had lower pain scores and decreased opioid consumption in the PACU compared to patients who received shorter-acting opioids in the intraoperative phase. Studies demonstrated that methadone use did not increase time to extubation at the end of surgery and was not associated with significant respiratory complications during recovery.

Conclusions

This review supports that incorporating intravenous methadone can yield a satisfactory analgesic profile for a wide array of surgeries, including ambulatory surgery, cardiac surgery, and intra-abdominal surgery. More clinical trials are needed to determine specific dosing guidelines and to vet the safety and efficacy in patients with various comorbidities.
目的:术后疼痛是一种独特的经历,可能具有挑战性。围手术期护理人员对多种药物干预有充分的了解是非常必要的。与其他术中阿片类药物相比,静脉注射美沙酮作为预防术后疼痛的工具尚未得到广泛研究。本系统综述的目的是为其在预防术后疼痛中的应用和有效性提供证据。设计:系统回顾。方法:本综述采用广泛的研究策略,寻找近十年(2014年至2024年1月)的相关出版物。使用的数据库包括MEDLINE (PubMed)和谷歌Scholar。在最初确定的129项研究中,根据纳入标准选择了7项相关临床试验、2项回顾性评价和1项系统评价。研究结果:术中接受足够剂量美沙酮的患者(定义为0.1至0.4 mg/kg理想体重的剂量)与术中接受短效阿片类药物的患者相比,PACU疼痛评分较低,阿片类药物消耗减少。研究表明,美沙酮的使用不会增加手术结束时拔管的时间,也不会与康复期间显著的呼吸并发症相关。结论:本综述支持静脉注射美沙酮可在多种手术中产生令人满意的镇痛效果,包括门诊手术、心脏手术和腹腔手术。需要更多的临床试验来确定具体的给药指南,并审查各种合并症患者的安全性和有效性。
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引用次数: 0
Considering “The Beef” 考虑到“牛肉”
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jopan.2025.08.014
Susan J. Fetzer PhD, RN
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引用次数: 0
Attitude and “Self-Compassion and Purpose” as Factors Influencing Nurses' Intentions to Engage in Mindful Self-care in the Perianesthesia Setting 态度、“自我同情与目的”是影响围麻醉环境下护士正念自我护理意向的因素。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jopan.2025.02.008
Brenda K. Sanya PhD, RN, CPAN , Dawn L. Denny PhD, RN, ONC , Rhoda A. Owens PhD, RN , Glenda Lindseth PhD, RN, FADA, FAAN , Thomas Petros PhD

Purpose

This study examined relationships among variables shaping intention to engage in mindful self-care in nurses working in the perianesthesia setting.

Design

The study employed a cross-sectional design guided by the Theory of Planned Behavior to explore relationships between variables.

Methods

An online survey, approved by the ethics board, collected data from 85 perianesthesia nurses recruited via the American Society of PeriAnesthesia Nurses Listserv. Participants completed the Modified Theory of Planned Behavior Questionnaire and the Mindful Self-care Scale.

Findings

Perceived behavioral control (r = 0.318, P = .003) and attitude (r = 0.616, P < .001) showed positive correlations with intentions to engage in self-care, while subjective norms had no significant association (r = −0.025, P = .821). Mindful awareness, perceived behavioral control, and self-compassion and purpose correlated significantly with most variables, except subjective norms. Regression analyses demonstrated attitude (β = 0.51, t = 5.63, P ≤ .001) and self-compassion and purpose (β = 0.29, t = 2.54, P = .013) as significant factors influencing the intention of perianesthesia nurses to engage in mindful self-care. Overall, the model for intent to engage in mindful self-care demonstrated a good fit using the significant factors from the Theory of Planned Behavior, F(8, 76) = 9.33; P = .001 with an adjusted R2 of 0.44. On average, perianesthesia nurses engaged in mindful self-care 2 to 3 days per week.

Conclusions

This cross-sectional study of perianesthesia nurses found attitude and self-compassion and purpose to be significant predictors of intention to engage in self-care for an average of 2 to 3 days per week. Findings from this study add evidence that positive attitude and self-compassion and purpose significantly influence nurses' intentions to engage in self-care, suggesting these factors are key targets for interventions to improve nurses' well-being and performance.
目的:本研究探讨影响围麻醉环境下护士正念自我护理意向的变量之间的关系。设计:本研究采用计划行为理论指导下的横断面设计,探讨变量之间的关系。方法:一项经伦理委员会批准的在线调查,收集了通过美国麻醉周围护士协会Listserv招募的85名麻醉周围护士的数据。参与者完成了修正计划行为理论问卷和正念自我照顾量表。结果:感知行为控制(r = 0.318, P = 0.003)和态度(r = 0.616, P = 0.44)。平均而言,围麻醉期护士每周进行2 - 3天的正念自我护理。结论:这项对围麻醉期护士的横断面研究发现,态度、自我同情和目的是每周平均2至3天自我护理意向的显著预测因子。本研究的结果进一步证明,积极的态度、自我同情和目的显著影响护士从事自我护理的意愿,这表明这些因素是改善护士幸福感和绩效的关键干预目标。
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引用次数: 0
The Effect of Waiting Time on the Surgical Stretcher in the Operating Room for Urological Surgery on Anxiety and Surgical Fear: A Comparative Cross-sectional Study 泌尿外科手术室担架等待时间对焦虑和手术恐惧的影响:一项比较横断面研究。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jopan.2025.02.018
Aynur Koyuncu RN, PhD , Erdoğan Yakıt RN, MSc

Purpose

This study was conducted to examine the effect of operating room waiting time on surgical fear and preoperative anxiety in patients undergoing urinary system surgery.

Design

This study was conducted as a comparative cross-sectional.

Methods

This study was conducted with 150 patients undergoing urinary system surgery at a state hospital in Turkey between December 2023 and July 2024. Data were collected using a Descriptive Characteristics Form, the Visual Analog Scale, and the Surgical Fear Questionnaire at two time points: before entering the operating room (T0) and before being placed on the surgical table (T1). Patients were divided into 2 groups based on waiting time: group A (<30 minutes) and group B (≥30 minutes). Statistical analysis was performed with SPSS 27.0 at a significance level of P less than .05.

Findings

Patients in groups A and B were similar in terms of descriptive characteristics and T0 assessment. However, at T1 assessment, patients in group B had significantly higher levels of anxiety (P = .002), short-term fear (P = .001), and total fear (P = .001) compared to group A. Waiting time had a significant effect on anxiety (β = 0.637, P = .001), short-term fear (β = 0.788, P = .001), and total fear (β = 0.536, P = .001).

Conclusions

Prolonged waiting time in the operating room significantly increases psychological burden by significantly increasing anxiety, short-term fear, and total fear levels in patients.
目的:探讨手术室等待时间对泌尿系统手术患者手术恐惧及术前焦虑的影响。设计:本研究采用比较横断面法。方法:本研究于2023年12月至2024年7月在土耳其一家州立医院接受泌尿系统手术的150例患者进行。采用描述性特征表、视觉模拟量表和手术恐惧问卷在两个时间点收集数据:进入手术室前(T0)和放在手术台上前(T1)。根据等待时间将患者分为两组:A组(结果:A组和B组患者在描述性特征和T0评估方面相似。然而,在T1评估时,B组患者的焦虑(P = 0.002)、短期恐惧(P = 0.001)和总恐惧(P = 0.001)水平显著高于a组。等待时间对焦虑(β = 0.637, P = 0.001)、短期恐惧(β = 0.788, P = 0.001)和总恐惧(β = 0.536, P = 0.001)有显著影响。结论:手术室候诊时间延长,患者的焦虑、短期恐惧和总恐惧水平显著增加,显著加重了患者的心理负担。
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引用次数: 0
The Role of Frailty and ASA Classification in Perioperative Risk Stratification for Esophagectomy Patients: A Decade-Long Retrospective Study 衰弱和ASA分级在食管切除术患者围手术期风险分层中的作用:一项长达十年的回顾性研究。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jopan.2025.04.002
Wongsakorn Chaochankit MD , Chutida Sungworawongpana MD

Purpose

To evaluate perioperative risk factors and the predictive accuracy of the modified frailty index (mFI-5) and American Society of Anesthesiologists' Physical Status (ASA-PS) classification in predicting high morbidity following esophagectomy.

Design

Retrospective study.

Methods

Predictors of high morbidity were identified using logistic regression, and the performance of mFI-5 and ASA-PS scores was assessed using receiver operating characteristic curves.

Findings

The high-morbidity rate was 48%. Significant predictors included ASA greater than or equal to 3, preoperative chemoradiotherapy, and prolonged Intensive Care Unit (ICU) and hospital stays. The ASA-PS classification offered better overall accuracy in predicting morbidity. While the mFI-5 showed high sensitivity, it exhibited poor specificity, resulting in a high false-positive rate.

Conclusions

Both mFI-5 and ASA-PS have limitations in predicting high morbidity after esophagectomy. However, a model that integrates various perioperative factors, particularly postoperative variables, demonstrated significance.
目的:评价改良虚弱指数(mFI-5)和美国麻醉医师协会身体状态(ASA-PS)分级在预测食管切除术后高发病率中的围手术期危险因素及预测准确性。设计:回顾性研究。方法:采用logistic回归方法确定高发病率的预测因素,并采用受试者工作特征曲线评估mFI-5和ASA-PS评分的表现。结果:高发病率为48%。重要的预测因素包括ASA大于或等于3,术前放化疗,延长重症监护病房(ICU)和住院时间。ASA-PS分类在预测发病率方面提供了更好的总体准确性。虽然mFI-5具有较高的敏感性,但特异性较差,导致假阳性率较高。结论:mFI-5和ASA-PS在预测食管切除术后高发病率方面存在局限性。然而,一个整合了各种围手术期因素,特别是术后变量的模型显示了其重要性。
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引用次数: 0
Comment on “The Effect of Postoperative Frailty on Morbidity and Mortality in Geriatric Hip Fracture Patients: Prospective Cohort Study” “老年髋部骨折患者术后虚弱对发病率和死亡率的影响:前瞻性队列研究”评论。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jopan.2025.07.018
Rachana Mehta PhD, Ranjana Sah MD
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引用次数: 0
Comparison of the Effects of a Melissa officinalis L. and Valerian Combination With Clonidine on Anxiety, Hemodynamic Changes, and Shivering in Knee Replacement Surgery: A Randomized Controlled Trial. 缬草和缬草联合可乐定对膝关节置换术中焦虑、血流动力学改变和颤抖的影响:一项随机对照试验。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-11-28 DOI: 10.1016/j.jopan.2025.06.015
Fatemeh Hasanzadeh Sablouei, Ebrahim Nasiri Formi, Hooshang Akbari, Seyed Esmaeil Shafiei, Ali Davoodi

Purpose: Total knee arthroplasty is a common orthopedic surgery that can cause anxiety, shivering, and hemodynamic changes in patients. The study aimed to compare the effects of a combination of valerian and Melissa officinalis (Norogol) with clonidine on anxiety, hemodynamic changes, and shivering in total knee replacement.

Design: A parallel-group randomized controlled trial was used.

Methods: Ninety-six patients were divided into 3 groups: a combination of valerian and M. officinalis (Norogol), clonidine, and a placebo, with 32 individuals in each group. Patients received one capsule each night, starting two nights before surgery. Anxiety levels were assessed before medication and before surgery using the Spielberger questionnaire. Shivering was evaluated using the Crossley-Mahajan scale during recovery. Hemodynamic changes were monitored before drug administration, during surgery, and after surgery. The analysis of variance test was employed to compare quantitative variables FINDINGS: There were no significant differences in age and gender among the groups. The average shivering score in the Norogol and clonidine groups was significantly lower than that of the placebo group up to 60 minutes after the operation (P < .001). Both obvious and hidden anxiety levels in the intervention groups decreased, while anxiety increased in the control group. Hemodynamic factors, including systolic blood pressure and heart rate, decreased in all three groups; however, there were no significant differences among the groups.

Conclusions: The results indicated that Norogol was as effective as clonidine in reducing shivering in patients after surgery. Although the intervention groups showed a decrease in both obvious and hidden anxiety, the reduction was not statistically significant.

目的:全膝关节置换术是一种常见的骨科手术,可引起患者焦虑、颤抖和血流动力学改变。该研究旨在比较缬草和梅利莎officinalis (Norogol)与可乐定在全膝关节置换术中对焦虑、血流动力学变化和颤抖的影响。设计:采用平行组随机对照试验。方法:96例患者分为缬草和officinalis (Norogol)联合用药组、可乐定组和安慰剂组,每组32例。从手术前两晚开始,患者每晚服用一粒胶囊。在服药前和手术前使用Spielberger问卷评估焦虑水平。在恢复过程中使用Crossley-Mahajan量表评估颤抖。在给药前、手术中和手术后监测血流动力学变化。采用方差检验分析比较数量变量。结果:各组间年龄、性别差异无统计学意义。手术后60分钟,诺洛戈尔组和可乐定组的平均颤抖评分显著低于安慰剂组(P < 0.001)。干预组明显焦虑和隐性焦虑水平均下降,对照组焦虑水平升高。血液动力学因素,包括收缩压和心率,在所有三组中都有所下降;然而,各组之间没有显著差异。结论:诺罗固与可乐定在减少术后患者寒战方面具有同等效果。虽然干预组的明显焦虑和隐性焦虑均有所减少,但减少的程度无统计学意义。
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引用次数: 0
Prescription Medication and Substance Use Among Graduate Nursing and Health Science Students: A Scoping Review of Incidence, Predictors, and Associated Factors. 护理和健康科学专业研究生的处方药和物质使用:发生率、预测因素和相关因素的范围审查。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-11-25 DOI: 10.1016/j.jopan.2025.07.017
Hallie J D Evans, Jennifer R Majumdar, Elizabeth B Wilkes, Susan P McMullan

Purpose: To synthesize evidence on the initiation of prescription medications, over-the-counter substances, illicit substances, and other coping mechanisms among graduate nursing and health science students, medical students, and medical residents during training. The review also sought to identify predisposing personal and academic factors, as well as school-related stressors, influencing substance use.

Design: Scoping review conducted per Arksey and O'Malley framework and PRISMA-ScR guidelines.

Methods: Four databases (PubMed, EMBASE, CINAHL, and Cochrane) were searched for studies published between 2013 and 2024. Inclusion criteria were graduate nursing, health science, and medical students and residents; initiation of medications or substances during training; and reporting of contributing factors or stressors. All citations were exported to Covidence for systematic review management. Of 941 initial citations, 655 abstracts were screened, 80 full-text articles were reviewed, and 25 studies met inclusion criteria.

Findings: High levels of stress, anxiety, and depression were consistently reported across student populations. Initiation of substances-including prescription medications (notably stimulants and anxiolytics), alcohol, and other stimulants-emerged as common coping mechanisms. Predisposing factors included preexisting mental health conditions, academic pressure, and cultural normalization of substance use within healthcare education. School-related stressors such as workload intensity, prolonged training hours, and high-stakes performance expectations strongly influenced initiation.

Conclusions: Graduate health science students and residents are at risk for stress-related substance use. These findings underscore the need for targeted institutional strategies that simultaneously address mental health and substance use. Future research should investigate long-term consequences of initiation and evaluate sustainable interventions that strengthen support systems, reduce reliance on substances, and promote well-being among healthcare trainees.

目的:综合研究护理与健康科学专业研究生、医学生和住院医师在培训期间使用处方药、非处方药、非法药物及其他应对机制的相关证据。该研究还试图找出影响药物使用的个人因素和学业因素,以及与学校有关的压力因素。设计:根据Arksey和O'Malley框架和PRISMA-ScR指南进行范围审查。方法:检索四个数据库(PubMed, EMBASE, CINAHL和Cochrane),检索2013年至2024年发表的研究。纳入标准为护理研究生、健康科学、医学生和住院医师;在培训期间开始使用药物或物质;并报告促成因素或压力源。将所有引文导出至covid - ence进行系统审查管理。在941篇初始引用中,筛选了655篇摘要,审查了80篇全文文章,25篇研究符合纳入标准。研究发现:高水平的压力、焦虑和抑郁在学生群体中一直被报道。开始使用药物——包括处方药(特别是兴奋剂和抗焦虑药)、酒精和其他兴奋剂——成为常见的应对机制。诱发因素包括先前存在的精神健康状况、学业压力和卫生保健教育中物质使用的文化正常化。与学校有关的压力源,如工作量强度、延长的培训时间和高风险的绩效预期,强烈影响了入会。结论:健康科学研究生和住院医师存在压力相关物质使用风险。这些发现强调需要有针对性的机构战略,同时解决精神卫生和药物使用问题。未来的研究应调查启动和评估可持续干预措施的长期后果,以加强支持系统,减少对物质的依赖,并促进保健受训人员的福祉。
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引用次数: 0
Bibliometric Analysis of Perioperative Sleep Disturbance From 2000 to 2023: Current Status and Development Trends. 2000 - 2023年围手术期睡眠障碍文献计量学分析:现状与发展趋势。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-11-25 DOI: 10.1016/j.jopan.2025.07.020
Piaoyu Chen, Xiang He

Purpose: Sleep disturbances are common, particularly in the perioperative setting, where they negatively impact postoperative recovery for patients. However, a thorough bibliometric analysis of perioperative sleep disturbances has yet to be conducted. We seeks to provide a comprehensive overview of the current landscape, significant areas of interest, and emerging trends in this field.

Design: This investigation analyzes academic publications derived from the Web of Science Core Collection database, spanning the period from 2000 to 2023, that pertain to perioperative sleep disturbances.

Methods: The bibliometric analysis was performed utilizing various software tools, including VOSviewer, CiteSpace, and the R package "bibliometrix".

Findings: A total of 3,175 articles from 525 countries and regions were reviewed, with the United States being the leading contributor. There has been a consistent annual increase in relative publications. Harvard University emerged as the predominant research institution in this area. The journal Otolaryngology-Head and Neck Surgery was identified as the most frequently published outlet, while Anesthesiology was the most cited journal. Frances Chung being the most prolific and frequently cited researcher. The primary focus of this research area revolves around the complications and treatment approaches related to sleep disturbances, with keywords such as "esketamine", "dexamethasone", and "prehabilitation" indicating emerging research trends.

Conclusions: This bibliometric study represents the first comprehensive overview of the research developments and trends concerning perioperative sleep disturbances over the past 24 years. The insights derived from this analysis highlight current research frontiers and potential areas of interest, serving as a valuable resource for scholars engaged in the study of perioperative sleep disturbances.

目的:睡眠障碍是常见的,特别是在围手术期,睡眠障碍对患者术后恢复有负面影响。然而,关于围手术期睡眠障碍的文献计量学分析尚未进行。我们试图提供一个全面的概述当前的景观,重要的兴趣领域,并在这一领域的新兴趋势。设计:本研究分析了Web of Science Core Collection数据库中2000年至2023年期间与围手术期睡眠障碍有关的学术出版物。方法:利用VOSviewer、CiteSpace和R软件包bibliometrix进行文献计量学分析。研究结果:共审查了来自525个国家和地区的3175篇文章,其中美国是主要贡献者。相关出版物逐年持续增加。哈佛大学成为这一领域的主要研究机构。《耳鼻喉头颈外科》(Otolaryngology-Head and Neck Surgery)杂志被认为是发表频率最高的期刊,而《麻醉学》(Anesthesiology)杂志被引用频率最高。Frances Chung是最多产,最常被引用的研究者。该研究领域主要围绕与睡眠障碍相关的并发症和治疗方法展开,关键词如“艾氯胺酮”、“地塞米松”和“康复”表明了新兴的研究趋势。结论:这项文献计量学研究首次全面概述了过去24年来围手术期睡眠障碍的研究进展和趋势。从该分析中获得的见解突出了当前的研究前沿和潜在的兴趣领域,为从事围手术期睡眠障碍研究的学者提供了宝贵的资源。
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引用次数: 0
Impact of the Preoperative Telenursing Program on Preoperative Stress and Surgical Cancellation Rates in Oncological Patients: An Experimental Study. 术前远程护理计划对肿瘤患者术前压力和手术取消率的影响:一项实验研究。
IF 2 4区 医学 Q2 NURSING Pub Date : 2025-11-20 DOI: 10.1016/j.jopan.2025.06.020
Carla Aparecida do Nascimento Mozer, Juliana do Carmo Gonçalves, Cindy Medici Toscano Rozetti, Rachel de Carvalho, Bruno Henrique Fiorin, Lorena Barros Furieri, Mirian Fioresi

Purpose: To evaluate the effects of a preoperative telenursing program on preoperative stress and surgical cancellation rates in oncological patients.

Design: Experimental post-test research with a control group.

Methods: The oncological surgical patients were randomly assigned to two groups. Patients in the control group participated in the face-to-face preoperative medical consultation and then awaited the date of the surgery at their residences without further contact with another health care professional. The intervention group, in addition to the preoperative medical consultation, received a telephone call (telenursing) from an experienced nurse who guided essential care to avoid patient-related surgical cancellation.

Findings: The intervention group presented a lower total score of preoperative stress level than the control group. Regarding the number of surgical cancellations, there were 14 cancellations in the control group, while in the intervention group, telenursing was able to reduce this metric to 0. As for the level of satisfaction, the telenursing program obtained an average of 97.65 points.

Conclusions: The oncological preoperative telenursing program reduced the level of stress and eliminated the number of surgical cancellations, showing a high level of satisfaction among patients.

目的:评价远程护理方案对肿瘤患者术前应激和手术取消率的影响。设计:实验后测试研究与对照组。方法:将肿瘤外科患者随机分为两组。对照组患者参加面对面的术前医疗咨询,然后在家中等待手术日期,不再与其他医疗保健专业人员联系。干预组除了术前医疗咨询外,还接到一位经验丰富的护士的电话(远程护理),该护士指导基本护理以避免与患者相关的手术取消。结果:干预组术前应激水平总分低于对照组。关于手术取消的数量,对照组有14例手术取消,而在干预组,远程护理能够将这一指标降低到0。满意度方面,远程护理项目平均得分为97.65分。结论:肿瘤术前远程护理方案降低了患者的压力水平,减少了手术取消次数,患者满意度较高。
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引用次数: 0
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Journal of Perianesthesia Nursing
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