Purpose: This study was conducted to determine the effect of active warming on intraoperative body temperature and comfort before total knee arthroplasty.
Design: This study was a randomized controlled trial designed according to the Consolidated Standards of Reporting Trials.
Methods: The study was conducted on 54 patients in a public hospital in Türkiye. In the study, patients in the intervention group were prewarmed for 30 minutes before surgery. The patients in the intervention and control groups were warmed with a warming bed during the surgery.
Findings: In this study, the first entry temperature to the operating room after anesthesia induction and the mean body temperature of the patients in the intervention group were higher than the control group. The mean comfort score of the patients in the intervention group was higher than the control group.
Conclusions: As a result of this study, we found that the combination of preoperative prewarming and intraoperative warming reduced the decrease in the patient's body temperature and increased the comfort.
Purpose: This study was conducted with the aim of investigating the effects of simultaneous administration of fentanyl and nitroglycerine on hemodynamic responses.
Design: This randomized controlled trial was conducted with 50 patients undergoing elective inguinal hernia surgery.
Methods: Patients were randomly divided into two groups. In one group, fentanyl (F) was administered 5 minutes before intubation and extubation. In the other group, in addition to F, sublingual nitroglycerine spray was administered 2 minutes before intubation and extubation. Systolic, diastolic, and mean blood pressure and heart rate were measured before, immediately after, and at 1, 3, and 5 minutes after both procedures.
Findings: Systolic, diastolic, and mean blood pressure and heart rate were significantly lower in the group receiving fentanyl and nitroglycerine than in the group receiving fentanyl alone. In both groups, a reduction in hemodynamic variables was observed immediately after both procedures, up to 5 minutes later, but it was significantly reduced in the group receiving simultaneous administration of the two drugs.
Conclusions: Co-administration of nitroglycerine and fentanyl significantly weakened the hemodynamic responses and reflexes induced by intubation and extubation during the anesthesia process. Preventing these unwanted complications can lead to safer anesthesia for susceptible patients.