Purpose: Total knee arthroplasty is a common orthopedic surgery that can cause anxiety, shivering, and hemodynamic changes in patients. The study aimed to compare the effects of a combination of valerian and Melissa officinalis (Norogol) with clonidine on anxiety, hemodynamic changes, and shivering in total knee replacement.
Design: A parallel-group randomized controlled trial was used.
Methods: Ninety-six patients were divided into 3 groups: a combination of valerian and M. officinalis (Norogol), clonidine, and a placebo, with 32 individuals in each group. Patients received one capsule each night, starting two nights before surgery. Anxiety levels were assessed before medication and before surgery using the Spielberger questionnaire. Shivering was evaluated using the Crossley-Mahajan scale during recovery. Hemodynamic changes were monitored before drug administration, during surgery, and after surgery. The analysis of variance test was employed to compare quantitative variables FINDINGS: There were no significant differences in age and gender among the groups. The average shivering score in the Norogol and clonidine groups was significantly lower than that of the placebo group up to 60 minutes after the operation (P < .001). Both obvious and hidden anxiety levels in the intervention groups decreased, while anxiety increased in the control group. Hemodynamic factors, including systolic blood pressure and heart rate, decreased in all three groups; however, there were no significant differences among the groups.
Conclusions: The results indicated that Norogol was as effective as clonidine in reducing shivering in patients after surgery. Although the intervention groups showed a decrease in both obvious and hidden anxiety, the reduction was not statistically significant.
Purpose: To synthesize evidence on the initiation of prescription medications, over-the-counter substances, illicit substances, and other coping mechanisms among graduate nursing and health science students, medical students, and medical residents during training. The review also sought to identify predisposing personal and academic factors, as well as school-related stressors, influencing substance use.
Design: Scoping review conducted per Arksey and O'Malley framework and PRISMA-ScR guidelines.
Methods: Four databases (PubMed, EMBASE, CINAHL, and Cochrane) were searched for studies published between 2013 and 2024. Inclusion criteria were graduate nursing, health science, and medical students and residents; initiation of medications or substances during training; and reporting of contributing factors or stressors. All citations were exported to Covidence for systematic review management. Of 941 initial citations, 655 abstracts were screened, 80 full-text articles were reviewed, and 25 studies met inclusion criteria.
Findings: High levels of stress, anxiety, and depression were consistently reported across student populations. Initiation of substances-including prescription medications (notably stimulants and anxiolytics), alcohol, and other stimulants-emerged as common coping mechanisms. Predisposing factors included preexisting mental health conditions, academic pressure, and cultural normalization of substance use within healthcare education. School-related stressors such as workload intensity, prolonged training hours, and high-stakes performance expectations strongly influenced initiation.
Conclusions: Graduate health science students and residents are at risk for stress-related substance use. These findings underscore the need for targeted institutional strategies that simultaneously address mental health and substance use. Future research should investigate long-term consequences of initiation and evaluate sustainable interventions that strengthen support systems, reduce reliance on substances, and promote well-being among healthcare trainees.
Purpose: Sleep disturbances are common, particularly in the perioperative setting, where they negatively impact postoperative recovery for patients. However, a thorough bibliometric analysis of perioperative sleep disturbances has yet to be conducted. We seeks to provide a comprehensive overview of the current landscape, significant areas of interest, and emerging trends in this field.
Design: This investigation analyzes academic publications derived from the Web of Science Core Collection database, spanning the period from 2000 to 2023, that pertain to perioperative sleep disturbances.
Methods: The bibliometric analysis was performed utilizing various software tools, including VOSviewer, CiteSpace, and the R package "bibliometrix".
Findings: A total of 3,175 articles from 525 countries and regions were reviewed, with the United States being the leading contributor. There has been a consistent annual increase in relative publications. Harvard University emerged as the predominant research institution in this area. The journal Otolaryngology-Head and Neck Surgery was identified as the most frequently published outlet, while Anesthesiology was the most cited journal. Frances Chung being the most prolific and frequently cited researcher. The primary focus of this research area revolves around the complications and treatment approaches related to sleep disturbances, with keywords such as "esketamine", "dexamethasone", and "prehabilitation" indicating emerging research trends.
Conclusions: This bibliometric study represents the first comprehensive overview of the research developments and trends concerning perioperative sleep disturbances over the past 24 years. The insights derived from this analysis highlight current research frontiers and potential areas of interest, serving as a valuable resource for scholars engaged in the study of perioperative sleep disturbances.
Purpose: To evaluate the effects of a preoperative telenursing program on preoperative stress and surgical cancellation rates in oncological patients.
Design: Experimental post-test research with a control group.
Methods: The oncological surgical patients were randomly assigned to two groups. Patients in the control group participated in the face-to-face preoperative medical consultation and then awaited the date of the surgery at their residences without further contact with another health care professional. The intervention group, in addition to the preoperative medical consultation, received a telephone call (telenursing) from an experienced nurse who guided essential care to avoid patient-related surgical cancellation.
Findings: The intervention group presented a lower total score of preoperative stress level than the control group. Regarding the number of surgical cancellations, there were 14 cancellations in the control group, while in the intervention group, telenursing was able to reduce this metric to 0. As for the level of satisfaction, the telenursing program obtained an average of 97.65 points.
Conclusions: The oncological preoperative telenursing program reduced the level of stress and eliminated the number of surgical cancellations, showing a high level of satisfaction among patients.

