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Current Problems in Pediatric and Adolescent Health Care最新文献

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Competency based medical education and trust in the learning environment 基于能力的医学教育与学习环境中的信任。
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-09-01 DOI: 10.1016/j.cppeds.2024.101640
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引用次数: 0
Competency based medical education – Where do I start? 基于能力的医学教育--从何入手？
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-31 DOI: 10.1016/j.cppeds.2024.101674
Mary E. Moffatt MD , Rashaan Ford MD , Brenda Nuncio Lujano MS , Suzanne Reed MD, MAEd , Alvin Singh MD , David A. Stewart MD , David A. Turner MD
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引用次数: 0
Competency-based medical education (CBME) in graduate medical education: Perspectives from learners, faculty, and program leaders 医学研究生教育中的 CBME：学员、教师和项目负责人的观点。
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-30 DOI: 10.1016/j.cppeds.2024.101677
Alexandria Card MD , Gabriel Daniels MD , Paul Bluth MD , Laura Chiel MD , Bruce Herman MD , Meghan O'Connor MD , Jill Plevinsky PhD , Debra Boyer MD, MHPE
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引用次数: 0
Competency-based medical education: Connecting training outcomes to patient care 基于能力的医学教育：将培训成果与病人护理联系起来。
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-14 DOI: 10.1016/j.cppeds.2024.101675
Daniel J. Schumacher MD, PhD, Med , Katherine Gielissen MD, MHS , Benjamin Kinnear MD, Med

Competency-based medical education (CBME) is a patient-centered and learner-focused approach to education where curricula are delivered in a manner tailored to the individuals’ learning needs, and assessment focuses on ensuring trainees achieve requisite and clearly specified learning outcomes. Despite calls to focus assessment on what matters for patients. In this article, the authors explore one aspect of this next era: the use of electronic health record clinical performance indicators, such as Resident-Sensitive Quality Measures (RSQMs) and TRainee Attributable and Automatable Care Evaluations in Real-time (TRACERs), for learner assessment. They elaborate on both the promise and the potential limitations of using such measures in a program of learner assessment.

以能力为基础的医学教育（CBME）是一种以患者为中心、以学员为重点的教育方法，其课程是根据个人的学习需求量身定制的，而评估的重点则是确保学员取得必要的、明确规定的学习成果。尽管人们呼吁将评估重点放在对患者重要的事情上。在这篇文章中，作者探讨了下一个时代的一个方面：使用电子健康记录临床表现指标，如住院医师敏感质量衡量标准（RSQMs）和实时受训者可归因和自动护理评估（TRACERs），对学员进行评估。他们详细阐述了在学习者评估计划中使用这些指标的前景和潜在局限性。
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引用次数: 0
Foreword: Preparing future pediatricians and pediatric subspecialists: Competency-based medical education – Part 2 前言：培养未来的儿科医生和儿科亚专科医生：基于能力的医学教育--第二部分。
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-13 DOI: 10.1016/j.cppeds.2024.101676
David A. Turner MD , Patricia Poitevien MD MSc
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引用次数: 0
Accelerating therapeutic development and clinical trial readiness for STXBP1 and SYNGAP1 disorders 加快 STXBP1 和 SYNGAP1 疾病的治疗开发和临床试验准备。
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101576

Gene-targeted therapies for genetic neurodevelopmental disorders (NDDs) are becoming a reality. The Center for Epilepsy and Neurodevelopmental Disorders (ENDD) is currently focused on the development of therapeutics for STXBP1 and SYNGAP1 disorders. Here we review the known clinical features of these disorders, highlight the biological role of STXBP1 and SYNGAP1, and discuss our current understanding of pathogenic mechanisms and therapeutic development. Finally, we provide our perspective as scientists and parents of children with NDDs, and comment on the current challenges for both clinical and basic science endeavors.

针对遗传性神经发育障碍（NDDs）的基因靶向疗法正在成为现实。癫痫和神经发育障碍中心（ENDD）目前正致力于开发针对STXBP1和SYNGAP1障碍的疗法。在此，我们回顾了这些疾病的已知临床特征，强调了 STXBP1 和 SYNGAP1 的生物学作用，并讨论了我们目前对致病机制和治疗开发的理解。最后，我们以科学家和 NDDs 患儿家长的双重身份提出了自己的观点，并对当前临床和基础科学工作所面临的挑战发表了看法。
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引用次数: 0
Genetic testing for unexplained epilepsy: A review of diagnostic approach, benefits, and referral algorithm 不明原因癫痫的基因检测：诊断方法、益处和转诊算法综述。
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101579

In the last several decades, advances in genetic testing have transformed the diagnostic and therapeutic approach to pediatric epilepsy. However, the interpretation of these genetic tests often requires expert analysis and counseling. For this reason, as our molecular understanding of the linkages between abnormal cerebral physiology and genetics has grown, so too has the field of clinical epilepsy genetics. Here we explore recent advances in genetic testing, describe the benefits of genetic testing in epilepsy, and provide a practice guideline for testing and referrals to specialized epilepsy genetics centers, highlighting the Epilepsy NeuroGenetics Initiative (ENGIN) Clinic and the Center for Epilepsy and Neurodevelopmental Disorders (ENDD) at the Children's Hospital of Philadelphia as an illustration of such a specialized center.

在过去的几十年里，基因检测技术的进步改变了小儿癫痫的诊断和治疗方法。然而，对这些基因检测结果的解释往往需要专家的分析和咨询。因此，随着我们对异常脑生理学和遗传学之间联系的分子认识不断加深，临床癫痫遗传学领域也在不断发展。在此，我们探讨了基因检测的最新进展，描述了癫痫基因检测的益处，并提供了检测和转诊到专业癫痫遗传学中心的实践指南，重点介绍了费城儿童医院的癫痫神经遗传学倡议（ENGIN）诊所和癫痫与神经发育障碍中心（ENDD），以说明此类专业中心的情况。
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引用次数: 0
Advances in big data and omics: Paving the way for discovery in childhood epilepsies 大数据和全息技术的进步：为发现儿童癫痫铺平道路。
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101634

The insights gained from big data and omics approaches have transformed the field of childhood genetic epilepsy. With an increasing number of individuals receiving genetic testing for seizures, we are provided with an opportunity to identify clinically relevant subgroups and extract meaningful observations from this large-scale clinical data. However, the volume of data from electronic medical records and omics (e.g., genomics, transcriptomics) is so vast that standardized methods, such as the Human Phenotype Ontology, are necessary for reliable and comprehensive characterization. Here, we explore the integration of clinical and omics data, highlighting how these approaches pave the way for discovery in childhood epilepsies.

从大数据和全息方法中获得的洞察力改变了儿童遗传性癫痫领域。随着越来越多的人接受癫痫发作基因检测，我们有机会识别与临床相关的亚组，并从这些大规模临床数据中提取有意义的观察结果。然而，来自电子病历和omics（如基因组学、转录组学）的数据量是如此庞大，以至于标准化方法（如人类表型本体）对于可靠和全面的特征描述是必不可少的。在此，我们将探讨临床数据与全息数据的整合，重点介绍这些方法如何为儿童癫痫的发现铺平道路。
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引用次数: 0
FOREWORD: Innovation in Managing Childhood Epilepsy-Part-2 前言：管理儿童癫痫的创新--第二部分。
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101654
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引用次数: 0
Editorial Board Page 编辑委员会页面
IF 3 4区 医学 Q1 PEDIATRICS
Current Problems in Pediatric and Adolescent Health Care
Pub Date : 2024-08-01 DOI: 10.1016/S1538-5442(24)00118-4
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引用次数: 0
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