In this article, we provide pediatric primary care providers (PCPs) with evidence-based recommendations to reduce the risk of life-threatening bacterial infections in pediatric patients with sickle cell disease (SCD). Standard practice guidelines for SCD comprehensive care are lacking in comparison to other chronic diseases. There is a need for continued advocacy for quality healthcare for patients with SCD, including updated standard-of-care guidelines. As a result of these concerning inequities, PCPs and specialty providers are forced to reference and compare recommendations across several different health organizations to identify the best practice. PCPs should feel empowered to follow augmented immunization schedules in pediatric patients with SCD. Immunizations and proper antibiotics can be lifesaving against invasive meningococcal and pneumococcal infections. We outline opportunities for improving quality of care in pediatric patients with SCD for PCPs in the community.
Bleeding symptoms in children create significant concern for families and pediatricians alike. This article aims to assist primary care providers in the evaluation of children with bleeding symptoms by reviewing the complexities inherent in diagnosing pediatric bleeding disorders, emphasizing the variability in clinical presentations, testing nuances, and aspects of common bleeding diatheses. The incidence of bleeding disorders among pediatric patients referred for bleeding symptoms and abnormal hemostatic screening remains variable, ranging from 4 % to 11 % across different institutions. A meticulous evaluation-including family history, medication review, and assessment of bleeding severity-is an essential first step in identifying potential bleeding disorders. In patients with a high index of suspicion we recommend screening testing including a complete blood count including blood smear for review, activated partial thromboplastin time (aPTT), prothrombin time (PT), von Willebrand factor (VWF) antigen and activity, and fibrinogen level. Common bleeding disorders in pediatrics include factor deficiencies (including von Willebrand disease) and platelet disorders. A collaborative approach between primary care providers and hematologists is paramount to optimizing outcomes for pediatric patients with bleeding symptoms.

