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Elucidating the role of unemployment in complex social inequalities in mental health: An intersectional mediation analysis of the cross-sectional Spanish National Health Surveys 阐明失业在心理健康的复杂社会不平等中的作用:西班牙全国健康调查的交叉调解分析。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-29 DOI: 10.1016/j.socscimed.2026.119041
Antonio Moreno-Llamas , Amaia Bacigalupe , Unai Martín , Miguel San Sebastián , Per E. Gustafsson
Women, migrants and those in manual occupations face barriers in the labor market and are more vulnerable to unemployment, which in turn may impact mental health and contributes to inequalities. Previous research has not considered the intertwinement of multiple inequalities. This study examined intersectional inequalities (intersecting gender, social class, and migration status) in poor mental health and the mediation role of unemployment in the Spanish adult population, using the 2012 and 2017 cross-sectional Spanish National Health Surveys (n = 22,383, 18–64 years, response rates: 89.6 % and 74.0 %). Mental health was measured using the GHQ-12 and classified into good and poor. Unemployment was classified as employed or unemployed. Gender (men or women), social class (manual or non-manual) and migration status (born in Spain or migrant) were cross-classified in eight intersectional strata. Intersectional mediation analysis showed that, compared to non-manual native men, poorer mental health was found in women, migrants and manual occupations (total effect). Unemployment completely mediates mental health inequalities in strata of men with manual occupations but partially in strata of women. Moreover, mental health inequality was explained by both higher unemployment prevalence (pure indirect effect) and by greater vulnerability to unemployment (mediated interaction effect) among native men and women in manual occupations and immigrant women in non-manual occupations compared to non-manual native men. In conclusion, complex mental health inequalities seem to be underpinned by the dual processes of higher risks and worse consequences of unemployment. Health policies should target strata of manual occupations since they were more likely to be unemployed.
妇女、移徙者和从事体力劳动的人在劳动力市场上面临障碍,更容易失业,这反过来又可能影响心理健康并助长不平等。以前的研究没有考虑多重不平等的相互交织。本研究利用2012年和2017年西班牙全国健康调查(n = 22,383,18-64岁,回复率:89.6% %和74.0% %),研究了西班牙成年人心理健康状况不佳的交叉不平等(交叉性别、社会阶层和移民身份)和失业的中介作用。使用GHQ-12来测量心理健康,并将其分为好和差。失业分为受雇和失业。性别(男性或女性)、社会阶层(手工或非手工)和移民身份(出生在西班牙或移民)被交叉分类为八个交叉阶层。交叉调解分析表明,与非体力劳动的土著男子相比,妇女、移民和体力职业的心理健康状况较差(总影响)。失业完全调解了从事体力劳动的男子阶层的心理健康不平等,但部分调解了妇女阶层的心理健康不平等。此外,与非体力劳动的土著男子相比,从事体力劳动的土著男子和妇女以及从事非体力劳动的移民妇女的失业率更高(纯粹的间接影响)和更容易失业(介导的相互作用效应)可以解释心理健康不平等。综上所述,复杂的心理健康不平等似乎是由失业的高风险和更严重后果的双重过程所支撑的。卫生政策应针对体力劳动者阶层,因为他们更有可能失业。
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引用次数: 0
Social determinants of brain structure and cognition 大脑结构和认知的社会决定因素。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-29 DOI: 10.1016/j.socscimed.2026.119045
Mahsa Mayeli , David Matuskey , for the Alzheimer's Disease Neuroimaging Initiative

Background

Socioeconomic disadvantage is recognized as a risk factor for cognitive decline, yet its associated neural pathways remain unclear. We investigated whether neighborhood disadvantage, measured by the Area Deprivation Index (ADI), was associated with cognitive performance in older adults and patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD), and whether structural brain differences explained this relationship.

Methods

Participants included 822 older adults (478 cognitively unimpaired [CU], 271 with MCI, and 73 with AD). Associations between ADI, cognition, and brain structure were examined using regression models adjusting for age and sex. Mediation analyses tested whether total brain volume accounted for ADI–cognition relationships.

Results

Higher ADI was associated with poorer cognitive performance across all domains in CU individuals (National ADI: memory β = −0.008, p < 0.001; executive function β = −0.005, p < 0.001; language β = −0.005, p < 0.001; visuospatial β = −0.004, p < 0.001) and across multiple domains in MCI (memory β = −0.007, p = 0.002; executive β = −0.007, p < 0.001). ADI was also associated with smaller total cerebral, gray, and white matter volumes in CU (State ADI and gray matter β = −2.37, FDR-p = 0.006) and greater white matter hyperintensity burden (β = 0.152, FDR-p = 0.009). Associations were weaker in MCI and absent in AD. Mediation analyses showed that total brain volume significantly mediated the effect of ADI on language performance (ACME p = 0.024; proportion mediated = 19.7 %, p = 0.036).

Conclusions

Neighborhood disadvantage is linked to widespread cognitive vulnerability and structural brain differences. However, brain volume explains only a small portion of these associations, suggesting that environmental and contextual factors shape cognitive performance through pathways that extend beyond structural neurodegeneration.
背景:社会经济劣势被认为是认知能力下降的危险因素,但其相关的神经通路尚不清楚。我们调查了以区域剥夺指数(ADI)衡量的邻里劣势是否与老年人、轻度认知障碍(MCI)和阿尔茨海默病(AD)患者的认知表现有关,以及大脑结构差异是否解释了这种关系。方法:参与者包括822名老年人(478名认知未受损[CU], 271名轻度认知障碍患者,73名AD患者)。使用年龄和性别调整后的回归模型检验了ADI、认知和大脑结构之间的关系。中介分析测试了脑容量总量是否与ad -认知关系有关。结果:高ADI与CU个体各领域较差的认知表现相关(National ADI: memory β = -0.008,p )。结论:邻里不利与广泛的认知脆弱性和大脑结构差异有关。然而,脑容量只能解释这些关联的一小部分,这表明环境和背景因素通过超出结构神经变性的途径塑造认知表现。
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引用次数: 0
"Empower and be empowered": Unveiling how community engagement influences residents' perceived health in high-density high-rise housing “授权和被授权”:揭示社区参与如何影响高密度高层住宅中居民的感知健康。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-29 DOI: 10.1016/j.socscimed.2026.119015
Weixuan Chen , Yuxiang Wang , Izzy Yi Jian , Kar Him Mo
Rapid urbanisation has contributed to the increasing prevalence of high-density high-rise housing (HDHRH) as a common urban typology worldwide. While HDHRH presents an efficient solution for land use in densely populated areas, it also introduces distinct challenges to residents' health and well-being, including potential social isolation and environmental stress. Existing research has highlighted the potential for community engagement to correlate with positive perceived health outcomes, yet the specific mechanisms and contextual factors at play in HDHRH remain under-explored. This paper explores how community engagement influences residents' perceived health in HDHRH, using Hong Kong's public housing as a case study. Employing a mixed-methods approach, the research combines structural equation modelling of survey data from 644 residents with interviews. The results reveal that community engagement is positively associated with perceived health both directly and indirectly through two key pathways: community satisfaction and collective learning. Community satisfaction mediates the relationship by fostering a sense of belonging and trust, whilst collective learning is linked to the acquisition of new skills and perspectives, which correlate with reduced isolation and enhanced self-efficacy. Additionally, the duration of residence moderates the engagement-satisfaction association, with longer-term residents deriving greater benefits. This research contributes to the literature by refining social capital theory and providing empirical evidence of the perceived health benefits associated with community engagement in HDHRH. It also offers practical insights for policymakers, urban planners and welfare organisations on designing and implementing community programmes.
快速的城市化导致高密度高层住宅(HDHRH)日益流行,成为世界范围内常见的城市类型。虽然HDHRH为人口密集地区的土地利用提供了有效的解决方案,但它也给居民的健康和福祉带来了明显的挑战,包括潜在的社会孤立和环境压力。现有的研究强调了社区参与与积极的感知健康结果相关的潜力,但在HDHRH中起作用的具体机制和背景因素仍未得到充分探索。本文以香港的公共房屋为个案,探讨社区参与如何影响HDHRH居民的感知健康。本研究采用混合方法,将644名居民的调查数据与访谈相结合,建立结构方程模型。结果表明,社区参与通过社区满意度和集体学习两个关键途径直接和间接地与感知健康呈正相关。社区满意度通过培养归属感和信任感来调节这种关系,而集体学习与获得新的技能和观点有关,这与减少孤立和增强自我效能有关。此外,居住的持续时间调节了参与-满意度的关联,长期居住获得更大的利益。本研究通过完善社会资本理论和提供与HDHRH社区参与相关的感知健康益处的经验证据,为文献做出了贡献。它还为政策制定者、城市规划者和福利组织提供了设计和实施社区项目的实际见解。
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引用次数: 0
A critical analysis of the Australian public consultation on childhood vaccine mandate introduction 对澳大利亚关于引入儿童疫苗授权的公众协商的批判性分析。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-29 DOI: 10.1016/j.socscimed.2026.119037
Sayali Gore , Katie Attwell , Emma Campbell , Jane Williams , Stacy M. Carter , Julie Leask , Kerrie Wiley
Several countries have revised their policies to make vaccine refusal more difficult. The role of the public in this process has seldom been examined. We analysed the public consultation process for the Australian government's 2016 ‘No Jab No Pay’ mandatory childhood vaccination policy to better understand who participated, their arguments, and how their contributions were incorporated into the legislative process.
Publicly available submissions and hearing transcripts were categorised by submitter type, stance on the legislation, and writing style. We undertook a qualitative reflexive thematic analysis of the submissions’ structure and content and compared our findings with the Inquiry Report.
Most public submissions (95 %) opposed the legislation. Vaccine-rejecting submitters focused on safety arguments to argue the legislation was unjustified, unethical or ineffective. Vaccine-supportive submitters focused on the importance of vaccination but supported or opposed the legislation based on positions that weighed collective goods against individual rights.
The findings of this analysis differed somewhat from the Inquiry Report that analysed the same evidence. The Report identified similar key legislation-specific concerns, but the committee's explicit position on the importance of vaccines meant that vaccination concerns were not considered relevant. The Report drew heavily on supportive arguments from academics, medical organisations, and government, while minimising critical arguments.
Our findings suggest a process that epistemically privileged expert opinion in favour of mandates and discounted testimony driven by experiences, emotion, and beliefs of opponents. Future consultations on vaccination policy might consider approaches which are designed to connect high quality evidence with the plural values of citizens.
一些国家修改了它们的政策,使拒绝接种疫苗变得更加困难。公众在这一过程中的作用很少受到审查。我们分析了澳大利亚政府2016年“不注射不付费”强制性儿童疫苗接种政策的公众咨询过程,以更好地了解谁参与了这项政策,他们的观点,以及他们的贡献是如何被纳入立法程序的。公开提交的意见书和听证会笔录按提交人的类型、对立法的立场和写作风格进行了分类。我们对提交材料的结构和内容进行了定性的反思性专题分析,并将我们的调查结果与调查报告进行了比较。大多数公众意见书(95% %)反对立法。拒绝接种疫苗的提交者将重点放在安全方面,认为该立法是不合理的、不道德的或无效的。支持疫苗的提交者关注疫苗接种的重要性,但基于权衡集体利益与个人权利的立场支持或反对立法。这项分析的结果与分析相同证据的调查报告有些不同。该报告确定了类似的主要立法具体问题,但委员会关于疫苗重要性的明确立场意味着疫苗接种问题不被认为是相关的。该报告大量引用了来自学术界、医疗机构和政府的支持性论点,同时尽量减少了批评性论点。我们的研究结果表明了一个过程,即在知识上特权专家意见,支持委托和折扣证词,由经验,情感和对手的信仰驱动。今后关于疫苗接种政策的磋商可能会考虑旨在将高质量证据与公民的多元价值观联系起来的方法。
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引用次数: 0
“It's more than just being in a place, it's more like a peace of mind”: Ontological security among residents of a transitional housing program implemented during the COVID-19 pandemic “这不仅仅是在一个地方,更像是一种内心的平静”:在2019冠状病毒病大流行期间实施的过渡性住房计划中,居民的本体安全。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-28 DOI: 10.1016/j.socscimed.2026.119038
Megan Comfort , Jennifer Amegashie , Jordana Hemberg , Richa Ruwala , Jennifer Lorvick

Background

Homelessness is a visible and persistent manifestation of social and structural inequity in the United States. When individuals experience homelessness, their ontological security, which refers to the sense of constancy, safety, and trust in daily life, is often deeply eroded. We explored the connections between embodied experiences and ontological security among residents of a transitional housing program implemented during the COVID-19 pandemic.

Methods

We conducted in-depth interviews between November 2022 and October 2023 with 24 former residents of Operation Safer Ground (OSG), an Alameda County, California program that provided non-congregate supportive housing for medically vulnerable people experiencing homelessness. Data were analyzed using reflexive thematic analysis.

Results

Participants described OSG residences as supporting physical wellbeing, comfort, and restoration. When experienced daily, these features contributed to embodied ease and ontological security for most participants. Rules and security measures often enhanced feelings of safety and order, but some residents found them infantilizing and destabilizing through inconsistent enforcement. OSG's low-barrier model of care produced mixed effects: for some, proximity to fellow residents' substance use, mental health crisis, or death heightened vigilance and anxiety; for others, being housed with family members and pets stabilized identity and strengthened continuity.

Conclusions

By exploring participants' embodied responses to the OSG program's physical environment, rules and regulations, and communal living, we were able to chart how experiences that evoke visceral feelings of safety, control, and well-being can influence ontological security in the context of a transitional housing program.
背景:无家可归是美国社会和结构不平等的一种明显而持久的表现。当个人经历无家可归时,他们的本体论安全感,即日常生活中的恒心、安全感和信任感,往往会受到严重侵蚀。我们探讨了2019冠状病毒病大流行期间实施的过渡性住房计划的居民的具体化体验与本体安全之间的联系。方法:我们在2022年11月至2023年10月期间对24名来自加利福尼亚州阿拉米达县的OSG项目的前居民进行了深度访谈,OSG项目为无家可归的医疗弱势群体提供非聚集性支持住房。数据分析采用反身性主题分析。结果:参与者将OSG住宅描述为支持身体健康,舒适和恢复。当日常体验时,这些特性有助于大多数参与者的具体化轻松和本体安全性。规则和安全措施通常会增强安全感和秩序感,但一些居民发现,由于执法不一致,这些规则和安全措施使人变得幼稚和不稳定。OSG的低障碍护理模式产生了混合效果:对一些人来说,接近其他居民的物质使用,精神健康危机或死亡提高了警惕和焦虑;对其他人来说,与家人和宠物住在一起稳定了身份,加强了连续性。结论:通过探索参与者对OSG项目的物理环境、规章制度和公共生活的具体反应,我们能够绘制出在过渡性住房项目背景下,唤起安全、控制和幸福感的本能感受如何影响本体论安全的图表。
{"title":"“It's more than just being in a place, it's more like a peace of mind”: Ontological security among residents of a transitional housing program implemented during the COVID-19 pandemic","authors":"Megan Comfort ,&nbsp;Jennifer Amegashie ,&nbsp;Jordana Hemberg ,&nbsp;Richa Ruwala ,&nbsp;Jennifer Lorvick","doi":"10.1016/j.socscimed.2026.119038","DOIUrl":"10.1016/j.socscimed.2026.119038","url":null,"abstract":"<div><h3>Background</h3><div>Homelessness is a visible and persistent manifestation of social and structural inequity in the United States. When individuals experience homelessness, their ontological security, which refers to the sense of constancy, safety, and trust in daily life, is often deeply eroded. We explored the connections between embodied experiences and ontological security among residents of a transitional housing program implemented during the COVID-19 pandemic.</div></div><div><h3>Methods</h3><div>We conducted in-depth interviews between November 2022 and October 2023 with 24 former residents of Operation Safer Ground (OSG), an Alameda County, California program that provided non-congregate supportive housing for medically vulnerable people experiencing homelessness. Data were analyzed using reflexive thematic analysis.</div></div><div><h3>Results</h3><div>Participants described OSG residences as supporting physical wellbeing, comfort, and restoration. When experienced daily, these features contributed to embodied ease and ontological security for most participants. Rules and security measures often enhanced feelings of safety and order, but some residents found them infantilizing and destabilizing through inconsistent enforcement. OSG's low-barrier model of care produced mixed effects: for some, proximity to fellow residents' substance use, mental health crisis, or death heightened vigilance and anxiety; for others, being housed with family members and pets stabilized identity and strengthened continuity.</div></div><div><h3>Conclusions</h3><div>By exploring participants' embodied responses to the OSG program's physical environment, rules and regulations, and communal living, we were able to chart how experiences that evoke visceral feelings of safety, control, and well-being can influence ontological security in the context of a transitional housing program.</div></div>","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"393 ","pages":"Article 119038"},"PeriodicalIF":5.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146127070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hygiene narratives as public health discourse: Constructing the national body and national identity in wartime China (New China Daily & Liberation Daily, 1937–1945) 卫生叙事作为公共卫生话语:战时中国国家主体与国家认同的建构(《新中国日报》、《解放日报》,1937-1945)。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-28 DOI: 10.1016/j.socscimed.2026.119025
Yanyang Ma, Meifang Zhang
During the War of Resistance Against Japan (1937–1945), China faced severe public health crises amid military and political upheaval, making hygiene and epidemic prevention critical to safeguarding public health and national survival. While the Communist Party of China (CPC) newspapers' role in wartime political culture is recognized, systematic research on how their hygiene discourse shaped national identity is scarce. This study adopted qualitative discourse analysis of 586 hygiene-related reports from New China Daily (1937–1941) and Liberation Daily (1941–1945), sourced from databases such as the National Newspaper Index, to explore their identity-construction mechanisms. It found that the newspapers adopted three interrelated strategies: popularizing scientific hygiene knowledge to reshape public perceptions, politicizing health campaigns to turn private practices into patriotic obligations, and embedding hygiene into daily life via education and institutions to consolidate collective consciousness. These narratives not only mobilized public support for the war but also localized Foucault's biopolitics and Douglas's purity and danger theory, redefining hygiene as a patriotic duty and collective resistance, illustrating how public health discourse shapes collective identity and drives public health practice in crises and broadening Western theories' applicability in the Chinese context.
抗日战争时期,中国在军政动荡中面临严重的公共卫生危机,卫生防疫成为保障人民健康和民族生存的关键。虽然中国共产党报纸在战时政治文化中的作用得到了承认,但关于其卫生话语如何塑造国家认同的系统研究却很少。本研究以《新中国日报》(1937-1941)和《解放日报》(1941-1945)的586篇卫生相关报道为研究对象,对其身份建构机制进行定性话语分析。研究发现,报纸采取了三种相互关联的策略:普及科学卫生知识,重塑公众观念;将卫生运动政治化,将私人实践转化为爱国义务;通过教育和机构将卫生融入日常生活,巩固集体意识。这些叙述不仅动员了公众对战争的支持,而且还将福柯的生命政治和道格拉斯的纯洁与危险理论本土化,将卫生重新定义为一种爱国责任和集体抵抗,说明了公共卫生话语如何塑造集体身份,并在危机中推动公共卫生实践,拓宽了西方理论在中国背景下的适用性。
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引用次数: 0
Why urban communities in low- and middle-income countries participate in global health research: A scoping review and fuzzy cognitive mapping summary 为什么低收入和中等收入国家的城市社区参与全球卫生研究:范围审查和模糊认知地图摘要。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-28 DOI: 10.1016/j.socscimed.2026.119039
Marie-Catherine Gagnon-Dufresne , Iván Sarmiento , Sarah Cooper , Md Mizanur Rahman , Protyasha Ghosh , Neil Andersson , Kate Zinszer

Background

Although community participation is a key strategy for decolonizing global health research, there are significant difficulties in the meaningful engagement of urban communities in low- and middle-income countries. Addressing barriers and leveraging enablers before beginning research could facilitate more equitable collaborations. To guide researchers in this endeavour, this scoping review mapped available evidence and identified factors influencing the participation of urban communities in global health research in low- and middle-income countries.

Methods

Following guidelines from the Joanna Briggs’ Institute and PRISMA-ScR, we searched six databases for articles published in English and French without date restriction. Two independent reviewers screened articles in two stages. We used narrative synthesis to describe included studies and fuzzy cognitive mapping to summarize categories of factors influencing participation.

Results

We included 59 of 7,994 articles identified. Studies covered 36 countries on five continents, with half using qualitative methods. They addressed diverse health issues, one third of them targeting environmental health. Terminology and approaches for community participation varied greatly. We identified 251 distinct factors influencing participation through 1623 relationships. Fuzzy cognitive mapping summarized the most influential categories including researcher-community relationships, contextual adaptation of methods/activities, community decision-making power, ease of planning/implementation, and valuing different knowledge types.

Conclusion

Results confirm that meaningful participation requires researchers sharing power and making space for community voices. Adopting reflexive and transformative approaches can balance power asymmetries in research partnerships for global health, a vital step in the broader efforts towards decolonization.
背景:虽然社区参与是全球卫生研究非殖民化的一项关键战略,但低收入和中等收入国家的城市社区有意义地参与存在重大困难。在开始研究之前解决障碍和利用促进因素可以促进更公平的合作。为了指导研究人员进行这项工作,这项范围审查绘制了现有证据图,并确定了影响低收入和中等收入国家城市社区参与全球卫生研究的因素。方法:根据Joanna Briggs' Institute和PRISMA-ScR的指南,我们检索了6个数据库中无日期限制的英文和法文发表的文章。两名独立评审员分两个阶段对文章进行筛选。我们用叙事综合来描述纳入的研究,用模糊认知映射来总结影响参与的因素类别。结果:我们纳入了7994篇文章中的59篇。研究覆盖了五大洲的36个国家,其中一半采用定性方法。它们处理各种卫生问题,其中三分之一针对环境卫生问题。社区参与的术语和方法各不相同。我们通过1623个关系确定了251个影响参与的不同因素。模糊认知映射总结了最具影响力的类别,包括研究人员-社区关系、方法/活动的情境适应性、社区决策能力、规划/实施的便利性以及对不同知识类型的重视。结论:研究结果证实,有意义的参与需要研究人员分享权力,为社区声音提供空间。采取反思和变革的办法可以平衡全球卫生研究伙伴关系中的权力不对称,这是实现非殖民化的更广泛努力中的一个重要步骤。
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引用次数: 0
Ethno-cultural risk of ante-natal lead exposure among South Asian women in the UK 英国南亚妇女产前铅暴露的民族文化风险
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-27 DOI: 10.1016/j.socscimed.2026.119034
Sharmind Neelotpol , Alastair WM. Hay , Mike W. Woolridge

Background

Maternal lead exposure, shaped by environmental and cultural factors, can transfer to the foetus. Culturally embedded practices among South Asian women, including dietary habits and traditional cosmetics, may increase exposure compared with Caucasian women. This study measured ante-natal blood lead levels in South Asian mothers in Leeds, UK, and examined associated environmental, ethno-cultural, lifestyle, and foetal outcome factors.

Methods

Pregnant SA and Caucasian women were recruited from Leeds, UK. Participants donated ante-natal blood sample, and completed a lifestyle questionnaire. BLLs were analysed using Inductively Coupled Plasma Mass-Spectrometry. Foetal birth outcomes were recorded after delivery.

Findings

A significant difference in BLL was observed between pregnant South Asian (n = 98) and Caucasian (n = 38) women living in the UK (t = 4.00, df = 134, p = 0.0005). For South Asian women alone, factors associated with raised BLLs were: living in a home built before 1970 (t = 2.558, df = 97, p = 0.012); using pesticides for gardening in SA (t = 2.880, p=0.005), purchasing fish (fresh or dried (shutki)) from ethnic shops (t = 3.494, p=0.001), shopping for cosmetics (PC11: surma, tilaka, sindoor) from ethnic shops (t = 3.251, p = 0.002); buying canned food (PC1: fruit juice, tomato, cola) from local markets (t = 3.101, p = 0.003), ‘use of amulets’ (proxy for a lifestyle choice) (t = 3.137, p = 0.002). Factors associated with decreased BLLs were: purchasing food (PC1: vegetables, canned food, fish) from supermarket (t = 4.280, p = 0.0001), high intake of Vitamin E (PC21: broccoli, kiwi, mango) (t = −3.321, p=0.001). No significant differences in birth outcomes were shown between the groups, apart from ‘Premature Rupture of the Membranes’ (t = 2.47, df = 134 p = 0.015).

Conclusion

The ethno-diversity of this study sample, its size and location, made it possible to identify risk factors for reducing body lead burden among South Asian participants living in the UK. Based on these findings, policy makers might update ‘lead-free lifestyle’ guidelines for reducing the overall body lead content among South Asian women; improving outcomes for minority ethnic and ‘hard-to-reach’ groups.
受环境和文化因素影响,母体铅暴露可转移给胎儿。与高加索女性相比,南亚女性的文化习俗,包括饮食习惯和传统化妆品,可能会增加接触。本研究测量了英国利兹的南亚母亲的产前血铅水平,并检查了相关的环境、民族文化、生活方式和胎儿结局因素。方法从英国利兹招募SA孕妇和白种人孕妇。参与者捐献了产前血液样本,并完成了一份生活方式问卷。用电感耦合等离子体质谱法分析bll。分娩后记录胎儿出生结果。FindingsA之间未发现显著差异在BLL怀孕南亚(n = 98)和高加索人(n = 38)女性生活在英国(4.00 t = ,df = 134,p = 0.0005)。仅就南亚女性而言,与bll升高相关的因素是:居住在1970年以前建造的房屋中(t = 2.558,df = 97,p = 0.012);在南南非使用杀虫剂(t = 2.880,p=0.005),从民族商店购买鱼(新鲜或干鱼(疏鱼))(t = 3.494,p=0.001),从民族商店购买化妆品(PC11: surma, tilaka, sindoor) (t = 3.251,p = 0.002);从当地市场购买罐装食品(PC1:果汁,西红柿,可乐)(t = 3.101,p = 0.003),“使用护身符”(代表生活方式的选择)(t = 3.137,p = 0.002)。与bll降低相关的因素是:从超市购买食品(PC1:蔬菜、罐头食品、鱼)(t = 4.280,p = 0.0001),高维生素E摄入量(PC21:西兰花、猕猕桃、芒果)(t = −3.321,p=0.001)。除了“胎膜早破”(t = 2.47,df = 134 p = 0.015)外,两组间的出生结局无显著差异。结论本研究样本的种族多样性,其规模和位置,使得确定减少居住在英国的南亚参与者体内铅负担的危险因素成为可能。根据这些发现,政策制定者可能会更新“无铅生活方式”指南,以降低南亚妇女的总体铅含量;改善少数民族和“难以接触”群体的成果。
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引用次数: 0
Interdisciplinary expertise to advance human-centered explainable AI 跨学科的专业知识,以推进以人为中心的可解释的人工智能。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-27 DOI: 10.1016/j.socscimed.2026.119036
Chloe R. Bennett , Heather Cole-Lewis , Stephanie Farquhar , Naama Haamel , Boris Babenko , Oran Lang , Mathias S. Fleck , Ilana Traynis , Charles Lau , Yun Liu , Ivor Horn , Courtney Lyles
The field of artificial intelligence (AI) is rapidly influencing health and healthcare, but bias and inadequate subgroup performance persists. Previous work has clearly outlined the need for more rigorous attention to data representativeness and model performance to advance population health and reduce bias. However, there is an opportunity to leverage best practices of social epidemiology, behavior science, and health services research to help develop hypotheses for associations found, particularly when using explainable AI (XAI) methods. This paper introduces a novel human-in-the-loop model that couples generative XAI with a wraparound interdisciplinary expert panel review process. This human-centered approach critically assesses AI model explanations from multiple perspectives, effectively identifying areas of bias and pinpointing directions for future research. We summarize the approach, highlighting processes and findings where the interdisciplinary expert panel produced interpretations which were historically and contextually informed. In particular, the interdisciplinary panel identified potential confounders and brought in scientific evidence from previous studies, which have clear implications to reduce bias. This promising human-centered framework not only maximizes multidisciplinary methodological rigor for AI model improvement and eventual implementation but also proactively fosters team science opportunities in future research.
人工智能(AI)领域正在迅速影响健康和医疗保健,但偏见和不充分的亚组表现仍然存在。以前的工作已经清楚地概述了需要更加严格地关注数据代表性和模型性能,以促进人口健康和减少偏见。然而,有机会利用社会流行病学、行为科学和卫生服务研究的最佳实践来帮助建立所发现的关联的假设,特别是在使用可解释的人工智能(XAI)方法时。本文介绍了一种新的人在环模型,该模型将生成式XAI与跨学科专家小组评审过程结合在一起。这种以人为本的方法从多个角度批判性地评估人工智能模型的解释,有效地识别偏见领域,并为未来的研究指明方向。我们总结了方法,突出跨学科专家小组产生的历史和背景信息解释的过程和发现。特别是,跨学科小组确定了潜在的混杂因素,并从以前的研究中引入了科学证据,这对减少偏见具有明确的意义。这个有希望的以人为中心的框架不仅最大限度地提高了人工智能模型改进和最终实施的多学科方法严谨性,而且还积极地在未来的研究中培养团队科学机会。
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引用次数: 0
Criminalizing homelessness: Longitudinal associations of police encounters and homeless sweeps with psychosocial health among the unhoused community in Los Angeles 将无家可归定为犯罪:洛杉矶无家可归者社区中警察遭遇和无家可归者扫荡与心理社会健康的纵向关联。
IF 5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-27 DOI: 10.1016/j.socscimed.2026.119033
Jessie Chien , Benjamin F. Henwood , Randall Kuhn
Cities across the United States are relying more on criminalization policies—including laws targeting behaviors deemed disruptive to public order, such as sleeping or camping in public spaces—to remove visible homelessness. How the enforcement of these policies impacts the health of unhoused people is unclear. The present study leverages monthly survey data from a prospective cohort of unhoused individuals in Los Angeles County (n = 731) to examine the longitudinal associations of experiences with police encounters and homeless sweeps on physical and psychosocial health. We estimated multilevel mixed-effects models using repeated monthly observations nested within individuals that adjusted for sociodemographic, housing, and health-related covariates. Police encounters and sweep experiences were associated with poorer self-rated physical health (police: β = 0.12, 95 %CI = [0.06,0.18]; sweeps: β = 0.10, 95 %CI = [0.03,0.16]) and greater psychological distress (police: β = 0.32, 95 %CI = [0.08,0.56]; sweeps: β = 0.35, 95 %CI = [0.08, 0.61] in the same month. Police encounters were also associated with same-month increases in feelings of loneliness (β = 0.07, 95 %CI = [0.02,0.13]). These effects were partly mediated by experiences of displacement, accounting for 22–34 % of the total effects, suggesting that enforcement-related displacement contributes to adverse health likely through disruptions to individuals’ physical and social environments. Greater cumulative exposure to police encounters and to sweeps was associated with poorer physical and psychosocial health over time. As federal courts continue to evaluate the legality of criminalization policies, this study provides empirical evidence of their measurable health harms towards unhoused individuals, offering a basis for local authorities to consider alternatives to criminalization.
美国各地的城市正在更多地依赖于刑事化政策——包括针对被认为破坏公共秩序的行为的法律,比如在公共场所睡觉或露营——来消除可见的无家可归现象。这些政策的执行如何影响无家可归者的健康尚不清楚。本研究利用来自洛杉矶县无家可归者前瞻性队列的月度调查数据(n = 731)来检查与警察接触和无家可归者扫荡的经历对身体和心理健康的纵向关联。我们使用嵌套在个体内的重复月度观察来估计多水平混合效应模型,并对社会人口统计学、住房和健康相关协变量进行了调整。警察遇到和扫描经验与贫穷有关自我报告身体健康(警察:β = 0.12,95 CI  % = [0.06,0.18];清洁工:β = 0.10,95 CI  % = [0.03,0.16])和更大的心理压力(警察:β = 0.32,95 CI  % = [0.08,0.56];清洁工:β = 0.35,95 CI  % = [0.08,0.61]在同一个月。与警察接触也与当月孤独感的增加有关(β = 0.07,95 %CI = [0.02,0.13])。这些影响部分由流离失所经历介导,占总影响的22% - 34% %,这表明与执法有关的流离失所可能通过破坏个人的身体和社会环境而对健康造成不利影响。随着时间的推移,警察遭遇和扫荡的累积暴露程度越高,身体和心理健康状况就越差。随着联邦法院继续评估刑事定罪政策的合法性,本研究提供了经验证据,证明这些政策对无家可归者的健康造成了可衡量的危害,为地方当局考虑替代刑事定罪提供了依据。
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