Pub Date : 2021-01-01DOI: 10.5336/MEDSCI.2020-79596
H. Savaş, E. Sayar
{"title":"Oxidant-Antioxidant Balance and Trace Elements in Children with Functional Dyspepsia","authors":"H. Savaş, E. Sayar","doi":"10.5336/MEDSCI.2020-79596","DOIUrl":"https://doi.org/10.5336/MEDSCI.2020-79596","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2020-78629
S. Kemer, H. Ergün
{"title":"The Awareness of Drug Classifications and Concept of High Risk Drug by Healthcare Workers and Their Place in Professional Practice","authors":"S. Kemer, H. Ergün","doi":"10.5336/medsci.2020-78629","DOIUrl":"https://doi.org/10.5336/medsci.2020-78629","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2021-81334
G. Aytekin, Eray Yıldız, Fatih Çölkesen, N. Akilli, Ş. Arslan, A. Çalışkaner
{"title":"5-Year Experience at a Single Center: Retrospective Analysis of 38 Patients with Hereditary Angioedema: A Descriptive Study","authors":"G. Aytekin, Eray Yıldız, Fatih Çölkesen, N. Akilli, Ş. Arslan, A. Çalışkaner","doi":"10.5336/medsci.2021-81334","DOIUrl":"https://doi.org/10.5336/medsci.2021-81334","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2020-80110
P. Sayın, H. Rk, Mustafa Altınay, Melis Tü RKEL ÖZKAN, M. Mihmanlı, S. Çınar
{"title":"Comparison of Pressure Controlled and Volume Controlled Ventilation in Morbidly Obese Patients Underwent Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Trial","authors":"P. Sayın, H. Rk, Mustafa Altınay, Melis Tü RKEL ÖZKAN, M. Mihmanlı, S. Çınar","doi":"10.5336/medsci.2020-80110","DOIUrl":"https://doi.org/10.5336/medsci.2020-80110","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70783208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/MEDSCI.2021-81673
mehmet uyar, Güllü Eren, M. Yücel
{"title":"Bir Üniversite Hastanesinde Araştırma Görevlisi Olarak Çalışan Hekimlerin Tükenmişlik Düzeyi ve İş Doyumu Durumlarının Belirlenmesi ve Etkileyen Faktörlerin Değerlendirilmesi","authors":"mehmet uyar, Güllü Eren, M. Yücel","doi":"10.5336/MEDSCI.2021-81673","DOIUrl":"https://doi.org/10.5336/MEDSCI.2021-81673","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"7 1","pages":"234-241"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75355369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2021-81574
N. Yılmaz, E. Eren, Cemil Öz, Zafer Kalayci, Ferhat Saribek
Viruses invade cells to reproduce, and they require an iron-filled cell for efficient reproduction. Together with other viruses, the coronavirus disease-2019 (COVID-19) virus can alter the expression of proteins involved in iron homeostasis. For example, in COVID-19 patients, an increase in pro-inflammatory cytokines such as interleukin-6 may stimulate the synthesis of hepcidin, the regulatory hormone of iron metabolism, thereby suppressing ferroportin-mediated cellular iron export. Increased serum levels of ferritin in COVID-19 virus infection is associated with a poor prognosis and may be partly due to the virus itself. Some viruses selectively infect iron acceptor cells (e.g. macrophages) by binding to transferrin receptor 1 during cell entry. Moreover, human airway secretions in the major route of entry of COVID-19 include transferrin and lactoferrin, and this glycoproteins can bind iron and maintain a chemically inert form. Understanding how iron metabolism and viral infection interact in the COVID-19 outbreak may suggest new ways to control the disease.
{"title":"COVID-19 and Iron Metabolism: Traditional Review","authors":"N. Yılmaz, E. Eren, Cemil Öz, Zafer Kalayci, Ferhat Saribek","doi":"10.5336/medsci.2021-81574","DOIUrl":"https://doi.org/10.5336/medsci.2021-81574","url":null,"abstract":"Viruses invade cells to reproduce, and they require an iron-filled cell for efficient reproduction. Together with other viruses, the coronavirus disease-2019 (COVID-19) virus can alter the expression of proteins involved in iron homeostasis. For example, in COVID-19 patients, an increase in pro-inflammatory cytokines such as interleukin-6 may stimulate the synthesis of hepcidin, the regulatory hormone of iron metabolism, thereby suppressing ferroportin-mediated cellular iron export. Increased serum levels of ferritin in COVID-19 virus infection is associated with a poor prognosis and may be partly due to the virus itself. Some viruses selectively infect iron acceptor cells (e.g. macrophages) by binding to transferrin receptor 1 during cell entry. Moreover, human airway secretions in the major route of entry of COVID-19 include transferrin and lactoferrin, and this glycoproteins can bind iron and maintain a chemically inert form. Understanding how iron metabolism and viral infection interact in the COVID-19 outbreak may suggest new ways to control the disease.","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"67 1","pages":"176-188"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80240270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2020-78094
Levent Özbek
ABS TRACT Objective: We use the most frequently used growth functions in the literature for estimating Turkey’s cumulative number of confirmed coronavirus disease-2019 (COVID-19) cases. We analyze Brody, Bertalanffy, Logistic, Generalized Logistic, Gompertz, Richards, Negative Exponential, Stevens, and Tanaka models for determining the appropriate model. Material and Methods: The number of cases of COVID-19 in Turkey between March 17, 2020 and July 12, 2020 were included in the study. The data used in the study were obtained from Johns Hopkins University. We used the most frequently used Non-linear growth models in the literature for estimating Turkey’s cumulative number of confirmed COVID-19 cases. Matlab software was used to estimate the parameters in the models studied. non-linear least squares regression function is used in Matlab software. Results: According to the estimation results, the best fitting model is the Richards model in terms of both the mean squared error and R 2 (coefficient of determination). Conclusion: We recommend to use the Richards model in modeling the cumulative COVID-19 cases. For estimating the future cases, it will be appropriate to use the Richards model. In addition, estimates of the number of daily cases obtained from the Richards model are not compatible with the actual number of daily cases. This may occur because estimations on these growth models can
{"title":"A Study on Determination of the Growth Models Using COVID-19 Cases Between March 17 and July 12 2020 in Turkey: Cross-sectional Study","authors":"Levent Özbek","doi":"10.5336/medsci.2020-78094","DOIUrl":"https://doi.org/10.5336/medsci.2020-78094","url":null,"abstract":"ABS TRACT Objective: We use the most frequently used growth functions in the literature for estimating Turkey’s cumulative number of confirmed coronavirus disease-2019 (COVID-19) cases. We analyze Brody, Bertalanffy, Logistic, Generalized Logistic, Gompertz, Richards, Negative Exponential, Stevens, and Tanaka models for determining the appropriate model. Material and Methods: The number of cases of COVID-19 in Turkey between March 17, 2020 and July 12, 2020 were included in the study. The data used in the study were obtained from Johns Hopkins University. We used the most frequently used Non-linear growth models in the literature for estimating Turkey’s cumulative number of confirmed COVID-19 cases. Matlab software was used to estimate the parameters in the models studied. non-linear least squares regression function is used in Matlab software. Results: According to the estimation results, the best fitting model is the Richards model in terms of both the mean squared error and R 2 (coefficient of determination). Conclusion: We recommend to use the Richards model in modeling the cumulative COVID-19 cases. For estimating the future cases, it will be appropriate to use the Richards model. In addition, estimates of the number of daily cases obtained from the Richards model are not compatible with the actual number of daily cases. This may occur because estimations on these growth models can","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2021-81607
Gülay Gülbol Duran, M. Terzi
{"title":"Investigation of Anti-Inflammatory Effects of Myrtus communis L. Essential Oil on IL-1β Induced Human Bronchial Epithelial Cell Line","authors":"Gülay Gülbol Duran, M. Terzi","doi":"10.5336/medsci.2021-81607","DOIUrl":"https://doi.org/10.5336/medsci.2021-81607","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70783054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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