Pub Date : 2021-01-01DOI: 10.5336/MEDSCI.2020-79596
H. Savaş, E. Sayar
{"title":"Oxidant-Antioxidant Balance and Trace Elements in Children with Functional Dyspepsia","authors":"H. Savaş, E. Sayar","doi":"10.5336/MEDSCI.2020-79596","DOIUrl":"https://doi.org/10.5336/MEDSCI.2020-79596","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2020-78629
S. Kemer, H. Ergün
{"title":"The Awareness of Drug Classifications and Concept of High Risk Drug by Healthcare Workers and Their Place in Professional Practice","authors":"S. Kemer, H. Ergün","doi":"10.5336/medsci.2020-78629","DOIUrl":"https://doi.org/10.5336/medsci.2020-78629","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2021-81334
G. Aytekin, Eray Yıldız, Fatih Çölkesen, N. Akilli, Ş. Arslan, A. Çalışkaner
{"title":"5-Year Experience at a Single Center: Retrospective Analysis of 38 Patients with Hereditary Angioedema: A Descriptive Study","authors":"G. Aytekin, Eray Yıldız, Fatih Çölkesen, N. Akilli, Ş. Arslan, A. Çalışkaner","doi":"10.5336/medsci.2021-81334","DOIUrl":"https://doi.org/10.5336/medsci.2021-81334","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2020-80110
P. Sayın, H. Rk, Mustafa Altınay, Melis Tü RKEL ÖZKAN, M. Mihmanlı, S. Çınar
{"title":"Comparison of Pressure Controlled and Volume Controlled Ventilation in Morbidly Obese Patients Underwent Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Trial","authors":"P. Sayın, H. Rk, Mustafa Altınay, Melis Tü RKEL ÖZKAN, M. Mihmanlı, S. Çınar","doi":"10.5336/medsci.2020-80110","DOIUrl":"https://doi.org/10.5336/medsci.2020-80110","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70783208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/MEDSCI.2021-81673
mehmet uyar, Güllü Eren, M. Yücel
{"title":"Bir Üniversite Hastanesinde Araştırma Görevlisi Olarak Çalışan Hekimlerin Tükenmişlik Düzeyi ve İş Doyumu Durumlarının Belirlenmesi ve Etkileyen Faktörlerin Değerlendirilmesi","authors":"mehmet uyar, Güllü Eren, M. Yücel","doi":"10.5336/MEDSCI.2021-81673","DOIUrl":"https://doi.org/10.5336/MEDSCI.2021-81673","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"7 1","pages":"234-241"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75355369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2021-81574
N. Yılmaz, E. Eren, Cemil Öz, Zafer Kalayci, Ferhat Saribek
Viruses invade cells to reproduce, and they require an iron-filled cell for efficient reproduction. Together with other viruses, the coronavirus disease-2019 (COVID-19) virus can alter the expression of proteins involved in iron homeostasis. For example, in COVID-19 patients, an increase in pro-inflammatory cytokines such as interleukin-6 may stimulate the synthesis of hepcidin, the regulatory hormone of iron metabolism, thereby suppressing ferroportin-mediated cellular iron export. Increased serum levels of ferritin in COVID-19 virus infection is associated with a poor prognosis and may be partly due to the virus itself. Some viruses selectively infect iron acceptor cells (e.g. macrophages) by binding to transferrin receptor 1 during cell entry. Moreover, human airway secretions in the major route of entry of COVID-19 include transferrin and lactoferrin, and this glycoproteins can bind iron and maintain a chemically inert form. Understanding how iron metabolism and viral infection interact in the COVID-19 outbreak may suggest new ways to control the disease.
{"title":"COVID-19 and Iron Metabolism: Traditional Review","authors":"N. Yılmaz, E. Eren, Cemil Öz, Zafer Kalayci, Ferhat Saribek","doi":"10.5336/medsci.2021-81574","DOIUrl":"https://doi.org/10.5336/medsci.2021-81574","url":null,"abstract":"Viruses invade cells to reproduce, and they require an iron-filled cell for efficient reproduction. Together with other viruses, the coronavirus disease-2019 (COVID-19) virus can alter the expression of proteins involved in iron homeostasis. For example, in COVID-19 patients, an increase in pro-inflammatory cytokines such as interleukin-6 may stimulate the synthesis of hepcidin, the regulatory hormone of iron metabolism, thereby suppressing ferroportin-mediated cellular iron export. Increased serum levels of ferritin in COVID-19 virus infection is associated with a poor prognosis and may be partly due to the virus itself. Some viruses selectively infect iron acceptor cells (e.g. macrophages) by binding to transferrin receptor 1 during cell entry. Moreover, human airway secretions in the major route of entry of COVID-19 include transferrin and lactoferrin, and this glycoproteins can bind iron and maintain a chemically inert form. Understanding how iron metabolism and viral infection interact in the COVID-19 outbreak may suggest new ways to control the disease.","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"67 1","pages":"176-188"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80240270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2021-83768
M. Pamukcu, T. Izci Duran
{"title":"Youtube as a Source of Information on Gout Disease: Cross-Sectional Evaluation","authors":"M. Pamukcu, T. Izci Duran","doi":"10.5336/medsci.2021-83768","DOIUrl":"https://doi.org/10.5336/medsci.2021-83768","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70783440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}