Pub Date : 2022-01-01DOI: 10.5336/medsci.2021-87249
Fatma Kurt Çolak, A. Bayram, Keziban KORKMAZ BAYRAM, M. Kırnap, M. Dündar, Ç. Saatçi
{"title":"Investigation of Relation Between MDR1 Gene and Ankylosing Spondylitis: Case Control Research","authors":"Fatma Kurt Çolak, A. Bayram, Keziban KORKMAZ BAYRAM, M. Kırnap, M. Dündar, Ç. Saatçi","doi":"10.5336/medsci.2021-87249","DOIUrl":"https://doi.org/10.5336/medsci.2021-87249","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70784637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/medsci.2021-85503
Insiat Islam Rabby, Farzad Hossain, M. Islam, A. Islam, I. Akhi, S. Huda
Our world is currently fighting with highly infectious and deadly severe acute respiratory syndrome-coronavirus-2 virus which has no specific remedy yet. No study focused on reviewing applied clinical management and treatment protocol of coronavirus disease-2019 (COVID-19) by health ministry of different nations till date. Therefore, this study focuses to identify and compare clinical management and treatment protocol guidelines for COVID-19 from 8 South Asian countries. This study will assist the healthcare workers and authorities of different nations by sharing the key information from potential guidelines to treat COVID-19 patients. Necessary information has been collected from the clinical management guidelines for COVID-19 in Health Ministry website of India, Bangladesh, Sri Lanka, Pakistan, Afghanistan, Nepal, Bhutan, and Maldives. Though clinical management practices vary from country to country, all of these countries are utilizing high flow oxygen therapy and mechanical ventilation for critical cases. Moreover, some potential drugs have been suggested for treatment by most of the countries but were not recommended yet as all of them are under clinical trials. Hydroxychloroquine has been suggested by most of these countries. All the countries are developing and updating their guidelines for clinical management of COVID-19 patients. It is worth mentioning that the recovery rate of Bangladesh, India, Sri Lanka, Pakistan, Afghanistan, Nepal, Bhutan, and Maldives is 63.52%, 76.24%, 94.88%, 94.47%, 83.65%, 71.5%, 71.14%, and 83.83% respectively. The oxygen therapy and empirical antibiotic for preventing secondary infection have been used commonly in most of these countries as an effective treatment.
{"title":"A Review of Clinical Management Practice of COVID-19 in South Asian Countries: Systematic Review","authors":"Insiat Islam Rabby, Farzad Hossain, M. Islam, A. Islam, I. Akhi, S. Huda","doi":"10.5336/medsci.2021-85503","DOIUrl":"https://doi.org/10.5336/medsci.2021-85503","url":null,"abstract":"Our world is currently fighting with highly infectious and deadly severe acute respiratory syndrome-coronavirus-2 virus which has no specific remedy yet. No study focused on reviewing applied clinical management and treatment protocol of coronavirus disease-2019 (COVID-19) by health ministry of different nations till date. Therefore, this study focuses to identify and compare clinical management and treatment protocol guidelines for COVID-19 from 8 South Asian countries. This study will assist the healthcare workers and authorities of different nations by sharing the key information from potential guidelines to treat COVID-19 patients. Necessary information has been collected from the clinical management guidelines for COVID-19 in Health Ministry website of India, Bangladesh, Sri Lanka, Pakistan, Afghanistan, Nepal, Bhutan, and Maldives. Though clinical management practices vary from country to country, all of these countries are utilizing high flow oxygen therapy and mechanical ventilation for critical cases. Moreover, some potential drugs have been suggested for treatment by most of the countries but were not recommended yet as all of them are under clinical trials. Hydroxychloroquine has been suggested by most of these countries. All the countries are developing and updating their guidelines for clinical management of COVID-19 patients. It is worth mentioning that the recovery rate of Bangladesh, India, Sri Lanka, Pakistan, Afghanistan, Nepal, Bhutan, and Maldives is 63.52%, 76.24%, 94.88%, 94.47%, 83.65%, 71.5%, 71.14%, and 83.83% respectively. The oxygen therapy and empirical antibiotic for preventing secondary infection have been used commonly in most of these countries as an effective treatment.","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70784733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/medsci.2021-87537
K. Garg, Tomar Ashish, S. Kataria, Mathur Aarushi, Raveendranath Perumal
{"title":"To Study the Pattern, Causality, Severity and Predictability of Adverse Drug Reactions in Patients on Cancer Chemotherapy: Descriptive Research-Qualitative Study","authors":"K. Garg, Tomar Ashish, S. Kataria, Mathur Aarushi, Raveendranath Perumal","doi":"10.5336/medsci.2021-87537","DOIUrl":"https://doi.org/10.5336/medsci.2021-87537","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70785099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-23DOI: 10.22541/AU.162704472.26250636/V1
T. Demir, M. Bitargil, H. E. Kilic, H. K. Çetin, Nilüfer Bektaş, B. Kasapoglu, K. Keskin, M. Sumerkan, O. Ser, H. Demir, A. Balkaya, U. Turkmen, S. Acar, N. Basi, D. Sevgi, Ahsen Oncul, M. Zengin, Birol Kabakçi, Ö. Alyan, Ayşe Surhan Çınar, I. Dokmetas, İ. Koramaz, H. M. Ozdemir
Background: Coronavirus disease 2019 (COVID-19) is commonly complicated with coagulopathy presented with venous thromboembolism and arterial thromboses. The aim of this study was to evaluate the effect of routine thromboprophylaxis with low molecular weight heparin (LMWH) on clinical outcomes including mortality and need for intensive care unit (ICU) admission in hospitalized COVID-19 patients. Methods: All confirmed patients with COVID-19 hospitalized to COVID-19 dedicated wards, from March 15 to May 15, 2020, were included in this retrospective cohort study. Two groups of patients were established, according to the non-routine and routine application of LMWH with therapeutic, weight-based, anticoagulation dosing. Clinical, laboratory and treatment data were collected, analyzed and compared between the two groups. A logistic regression model was developed to assess the factors related to in-hospital adverse outcomes. Results: A total of 1511 patients (797 men, median age 59.0 years) were retrospectively analyzed (Group non-routine LMWH (n=828); group routine LMWH (n=683)). Multivariate logistic regression analysis showed routine use of LMWH, favipiravir administration, extreme values of WBC count, NLR, and troponin I as factors independently associated with in-hospital adverse outcomes (OR=0.25, 95% CI: 0.83-0.91; p<0.001 for routine use of LMWH). Conclusion: Routine thromboprophylaxis with LMWH reduced mortality and ICU admission in patients admitted with COVID-19 infection.
{"title":"Effect of Routine Thromboprophylaxis with Low Molecular Weight Heparin in Hospitalized Covid-19 Patients","authors":"T. Demir, M. Bitargil, H. E. Kilic, H. K. Çetin, Nilüfer Bektaş, B. Kasapoglu, K. Keskin, M. Sumerkan, O. Ser, H. Demir, A. Balkaya, U. Turkmen, S. Acar, N. Basi, D. Sevgi, Ahsen Oncul, M. Zengin, Birol Kabakçi, Ö. Alyan, Ayşe Surhan Çınar, I. Dokmetas, İ. Koramaz, H. M. Ozdemir","doi":"10.22541/AU.162704472.26250636/V1","DOIUrl":"https://doi.org/10.22541/AU.162704472.26250636/V1","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19) is commonly complicated\u0000with coagulopathy presented with venous thromboembolism and arterial\u0000thromboses. The aim of this study was to evaluate the effect of routine\u0000thromboprophylaxis with low molecular weight heparin (LMWH) on clinical\u0000outcomes including mortality and need for intensive care unit (ICU)\u0000admission in hospitalized COVID-19 patients. Methods: All confirmed\u0000patients with COVID-19 hospitalized to COVID-19 dedicated wards, from\u0000March 15 to May 15, 2020, were included in this retrospective cohort\u0000study. Two groups of patients were established, according to the\u0000non-routine and routine application of LMWH with therapeutic,\u0000weight-based, anticoagulation dosing. Clinical, laboratory and treatment\u0000data were collected, analyzed and compared between the two groups. A\u0000logistic regression model was developed to assess the factors related to\u0000in-hospital adverse outcomes. Results: A total of 1511 patients (797\u0000men, median age 59.0 years) were retrospectively analyzed (Group\u0000non-routine LMWH (n=828); group routine LMWH (n=683)). Multivariate\u0000logistic regression analysis showed routine use of LMWH, favipiravir\u0000administration, extreme values of WBC count, NLR, and troponin I as\u0000factors independently associated with in-hospital adverse outcomes\u0000(OR=0.25, 95% CI: 0.83-0.91; p<0.001 for routine use of\u0000LMWH). Conclusion: Routine thromboprophylaxis with LMWH reduced\u0000mortality and ICU admission in patients admitted with COVID-19\u0000infection.","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"65 Suppl 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68201140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2020-79320
S. Uludağ, D. E. Tekcan Şanlı, Nazım Güreş, A. Şanlı, A. Zengin
{"title":"Zenker's Diverticulum: 20 Years of Experience and Outcomes of Surgical Resection","authors":"S. Uludağ, D. E. Tekcan Şanlı, Nazım Güreş, A. Şanlı, A. Zengin","doi":"10.5336/medsci.2020-79320","DOIUrl":"https://doi.org/10.5336/medsci.2020-79320","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2020-80805
Gamze ÖZTÜRK KARABULUT, Zehra Karaagac, D. Bektaşoğlu, K. Fazıl, K. Serefoglu Cabuk, S. Asik Nacaroglu, M. Taşkapılı
{"title":"Factors Affecting Success in Canalicular Laceration Repair","authors":"Gamze ÖZTÜRK KARABULUT, Zehra Karaagac, D. Bektaşoğlu, K. Fazıl, K. Serefoglu Cabuk, S. Asik Nacaroglu, M. Taşkapılı","doi":"10.5336/medsci.2020-80805","DOIUrl":"https://doi.org/10.5336/medsci.2020-80805","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70783248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/MEDSCI.2020-78127
E. Sari, A. Yazıcı, Gozde Sahin, Cenap Güler, Fatih Kenar
{"title":"Longitudinal Changes in Macular Thickness After Retropupillary Iris Claw Intraocular Lens Implantation: A 1-year Observational Study and Comparison with Scleral Fixated Intraocular Lenses","authors":"E. Sari, A. Yazıcı, Gozde Sahin, Cenap Güler, Fatih Kenar","doi":"10.5336/MEDSCI.2020-78127","DOIUrl":"https://doi.org/10.5336/MEDSCI.2020-78127","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"16 1","pages":"7-14"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74585646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/MEDSCI.2021-82021
Özge Göksu Körlü, Uğur Dal, F. Dağ, Zeynep Altınkaya, A. Özgür, Havva Didem Çelikcan, Ö. B. Çimen
{"title":"The Evaluation of Walking Energy Consumption and Plantar Pressure Distribution in Patients with Lumbar Spinal Stenosis: A cross-sectional, case control study","authors":"Özge Göksu Körlü, Uğur Dal, F. Dağ, Zeynep Altınkaya, A. Özgür, Havva Didem Çelikcan, Ö. B. Çimen","doi":"10.5336/MEDSCI.2021-82021","DOIUrl":"https://doi.org/10.5336/MEDSCI.2021-82021","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"3 1","pages":"158-165"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79055160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/MEDSCI.2020-79276
A. Yiğin, M. Seven
{"title":"Evaluation of Clinical and Laboratory Findings of Patients with Klinefelter Syndrome: Single Center Experience","authors":"A. Yiğin, M. Seven","doi":"10.5336/MEDSCI.2020-79276","DOIUrl":"https://doi.org/10.5336/MEDSCI.2020-79276","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70782816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5336/medsci.2021-84825
Ebral Yiğit, Yasemin Demir Yiğit
{"title":"Seasonal Changes in the Incidence of Appendicitis in Diyarbakır, Turkey: Retrospective Study","authors":"Ebral Yiğit, Yasemin Demir Yiğit","doi":"10.5336/medsci.2021-84825","DOIUrl":"https://doi.org/10.5336/medsci.2021-84825","url":null,"abstract":"","PeriodicalId":49403,"journal":{"name":"Turkiye Klinikleri Tip Bilimleri Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70784016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：