Sleep Medicine Reviews最新文献_第2页

Defining circadian health: Conceptual framework and development of a circadian health index. 定义昼夜健康：昼夜健康指数的概念框架和发展。

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2026-01-28 DOI: 10.1016/j.smrv.2026.102244

Julien Coelho, Jean-Arthur Micoulaud-Franchi, Pierre-Alexis Geoffroy, Pierre Philip, Jacques Taillard, Patrice Bourgin

Circadian rhythms are key determinants of physical and mental health at the nexus of physiology and behavior. Classically, endogenous circadian rhythms are characterized according to three principal dimensions: circadian phase, amplitude and stability. From a behavioral perspective, the timing and regularity of nychthemeral behaviors represent two additional dimensions, and we propose as a sixth dimension the sleep complaints arising from a circadian disruption due to a mismatch between circadian physiology and nycthemeral behaviors. This article reviews each of these dimensions and examines their interactions, along with their effects on sleep and health. On this basis, we propose an integrated definition of circadian health. We then review both, objective (melatonin, temperature, actimetry) and subjective (sleep diaries, self-report questionnaires) tools for assessing each of the circadian health dimensions. Finally, we propose a novel tool aimed at assessing those circadian health dimensions as well as the computation of a composite index to quantify circadian health, along with a graphical representation to visualize it. While further validation is still needed, this proposal will help clinicians and researchers better decipher circadian rhythms and their impact on mental and physical health and may offer new opportunities for public health promotion in both general and clinical populations.

昼夜节律是生理和行为关系中生理和心理健康的关键决定因素。经典地，内源性昼夜节律根据三个主要维度来表征：昼夜节律相位、幅度和稳定性。从行为学的角度来看，夜生理行为的时间和规律性代表了两个额外的维度，我们提出了第六个维度，即由于昼夜生理和夜生理行为之间的不匹配而导致的昼夜节律中断所引起的睡眠抱怨。本文回顾了这些方面，并研究了它们之间的相互作用，以及它们对睡眠和健康的影响。在此基础上，我们提出了昼夜健康的综合定义。然后，我们回顾了评估每个昼夜健康维度的客观工具（褪黑激素、体温、活动测量）和主观工具（睡眠日记、自我报告问卷）。最后，我们提出了一种新的工具，旨在评估这些昼夜节律健康维度，以及量化昼夜节律健康的复合指数的计算，以及将其可视化的图形表示。虽然还需要进一步的验证，但这一建议将帮助临床医生和研究人员更好地破译昼夜节律及其对精神和身体健康的影响，并可能为普通和临床人群的公共健康促进提供新的机会。

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引用次数: 0

Investigating the association between post-traumatic stress disorder and REM sleep behavior disorder: a systematic review 调查创伤后应激障碍和快速眼动睡眠行为障碍之间的关系：一个系统的回顾

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2026-01-28 DOI: 10.1016/j.smrv.2026.102245

Valentina Baldini , Martina Gnazzo , Giorgia Varallo , Diana De Ronchi , Fabio Pizza , Giuseppe Plazzi , Elena Antelmi

Post-traumatic stress disorder (PTSD) is frequently accompanied by additional sleep disturbances, such as nightmares and insomnia. Recent findings suggest a potential association between PTSD and REM sleep behavior disorder (RBD). This systematic review evaluates the current evidence on the PTSD–RBD relationship, with attention to prevalence, diagnostic approaches, shared pathophysiological mechanisms, and clinical implications.

A comprehensive search of PubMed, Web of Science, EMBASE, and PsycINFO was conducted up to July 2025. Eligible studies included observational, cohort, and experimental designs assessing RBD in individuals with PTSD. Methodological quality was appraised using the Newcastle–Ottawa Scale.

Seven studies, encompassing 4152 participants, met the inclusion criteria. Overall, PTSD was linked to a higher prevalence of probable or confirmed RBD, particularly among veterans. Adding to this, patients with isolated RBD appeared more likely to report comorbid PTSD than those diagnosed with other parasomnias. Evidence also indicated that PTSD-related RBD may be associated with more severe psychopathology, including heightened depressive symptoms, recurrent nightmares, and emotional dysregulation.

From a clinical standpoint, it is advisable to evaluate PTSD patients presenting with parasomnia symptoms for possible RBD, and to investigate PTSD history in those exhibiting dream enactment behaviors.

创伤后应激障碍（PTSD）经常伴有额外的睡眠障碍，如噩梦和失眠。最近的研究结果表明，创伤后应激障碍和快速眼动睡眠行为障碍（RBD）之间存在潜在的联系。这篇系统综述评估了目前PTSD-RBD关系的证据，包括患病率、诊断方法、共同的病理生理机制和临床意义。对PubMed、Web of Science、EMBASE和PsycINFO进行了全面的检索，截止到2025年7月。符合条件的研究包括观察性、队列性和实验性设计，评估PTSD患者的RBD。采用纽卡斯尔-渥太华量表评价方法质量。包括4152名参与者的7项研究符合纳入标准。总的来说，创伤后应激障碍与可能或确诊的RBD患病率较高有关，特别是在退伍军人中。除此之外，孤立性RBD患者比诊断为其他睡眠异常的患者更有可能报告合并PTSD。证据还表明，ptsd相关的RBD可能与更严重的精神病理相关，包括加重的抑郁症状、反复的噩梦和情绪失调。从临床的角度来看，建议评估出现睡眠异常症状的PTSD患者是否有可能出现RBD，并调查那些表现出梦境行为的患者的PTSD病史。

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引用次数: 0

Association between sleep duration and fluid biomarkers of Alzheimer's disease: A systematic review 睡眠时间与阿尔茨海默病液体生物标志物之间的关系：一项系统综述

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2026-01-23 DOI: 10.1016/j.smrv.2026.102242

Vanessa M. Young , Joy Zeynoun , Agustin Ruiz Laza , Arash Salardini , Christopher R. Frei , Christine Gaspard , Tiffany Kautz , Thiago Macedo e Cordeiro , Matthew P. Pase , Jonathan Gelfond , Jayandra Jung Himali , Antonio L. Teixeira , Sudha Seshadri , Andrée-Ann Baril

This systematic review (PROSPERO CRD420246206360) investigated relationships between self-reported or objective sleep duration and fluid biomarkers of Alzheimer's disease pathology and neurodegeneration: cerebrospinal fluid or blood Aβ, p-tau181, t-tau, NfL and GFAP. We searched PubMed, SCOPUS, and CINAHL from inception to September 2024. Twenty studies (n = 12,445) met inclusion criteria (13 cerebrospinal fluid biomarkers [n = 2836]; 7 blood biomarkers [n = 9609]). Study quality was assessed using Newcastle-Ottawa scales. Whereas many studies did not report any associations, some trends emerged: short sleep duration was associated with higher cerebrospinal fluid t-tau and p-tau181 and lower cerebrospinal fluid or blood Aβ42 across multiple studies. Longer sleep duration showed more variable associations, with some suggesting either worse or better biomarker profiles (e.g., higher and lower fluid t-tau, p-tau181, or Aβ42). Two studies investigating non-linear relationships identified U-shaped associations, suggesting both short (≤5–6 h) and long (≥8 h) sleep durations are associated with altered biomarker profiles. The predominantly cross-sectional and high heterogeneity of the available evidence, as well as the relatively small number of studies by individual biomarker (especially for NfL and GFAP) limit conclusions about sleep-biomarker relationships. Future research should investigate emerging blood-based biomarkers and explore temporal associations between sleep duration and Alzheimer's disease biomarker changes.

本系统综述（PROSPERO CRD420246206360）调查了自我报告或客观睡眠时间与阿尔茨海默病病理和神经退行性变的液体生物标志物：脑脊液或血液Aβ、p-tau181、t-tau、NfL和GFAP之间的关系。我们检索了PubMed， SCOPUS和CINAHL，从成立到2024年9月。20项研究（n = 12,445）符合纳入标准（13项脑脊液生物标志物[n = 2836]； 7项血液生物标志物[n = 9609]）。采用纽卡斯尔-渥太华量表评估研究质量。尽管许多研究没有报告任何关联，但出现了一些趋势：在多项研究中，睡眠时间短与脑脊液t-tau和p-tau181升高以及脑脊液或血液a - β42降低有关。较长的睡眠时间显示出更多的可变关联，其中一些表明生物标志物谱或差或好（例如，液体t-tau、p-tau181或a - β42较高或较低）。两项调查非线性关系的研究发现了u型关联，表明短睡眠时间（≤5-6小时）和长睡眠时间（≥8小时）都与生物标志物谱的改变有关。现有证据的主要横断面和高度异质性，以及个体生物标志物（特别是NfL和GFAP）的研究数量相对较少，限制了关于睡眠生物标志物关系的结论。未来的研究应调查新兴的血液生物标志物，并探索睡眠时间与阿尔茨海默病生物标志物变化之间的时间关联。

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引用次数: 0

The association between gut microbiota and insomnia: A systematic review and meta-analysis 肠道微生物群与失眠之间的关系：一项系统综述和荟萃分析

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2026-01-21 DOI: 10.1016/j.smrv.2026.102236

Shucheng Chen , Han Li , Meng Ning , Branda Yee Man Yu , Shirong Wu , Wai-yin Cheng , Yamin Li , Wing Fai Yeung

Emerging evidence suggests interactions between gut microbiota and sleep regulation, but specific associations with insomnia remain unclear. This systematic review evaluated alterations in gut microbiota in patients with insomnia compared with healthy controls. A systematic literature search was performed on eight databases from inception to June 2025. Case-control, cohort, and cross-sectional studies examining gut microbiota in adults with insomnia versus healthy controls were included. Fourteen studies encompassing 9036 participants (58.4 % female) were included. Alpha diversity was reduced in patients with insomnia in most of the included studies, among which observed species significantly decreased (SMD: 0.90, 95 % CI: 1.39, −0.40, k = 5). Beta diversity analysis revealed a consistently distinct microbial community structure between individuals with insomnia and healthy controls. Taxonomically, insomnia correlated with shifted Firmicutes-to-Bacteroidetes ratios. Meta-analyses revealed alterations in key genera, including significantly decreased Faecalibacterium and Lachnospira, and significantly increased Blautia and Eubacterium hallii. Changes in gut microbiota were also correlated with inflammatory markers and metabolic disturbances. In summary, gut microbiota dysbiosis was associated with insomnia and characterized by reduced microbial diversity and altered bacterial composition. These findings suggest potential applications for microbial biomarkers in insomnia diagnosis and subtyping, and the development of personalized microbiota-targeted interventions.

新出现的证据表明，肠道微生物群与睡眠调节之间存在相互作用，但与失眠的具体联系尚不清楚。本系统综述评估了失眠患者与健康对照者肠道微生物群的变化。从成立到2025年6月，对8个数据库进行了系统的文献检索。包括病例对照、队列和横断面研究，检查失眠成人与健康对照者的肠道微生物群。纳入14项研究，共9036名参与者（58.4%为女性）。在大多数纳入的研究中，失眠患者的α多样性降低，其中观察物种显著降低（SMD: 0.90, 95% CI: 1.39, - 0.40, k = 5）。β多样性分析显示，失眠患者和健康对照者之间的微生物群落结构一致不同。从分类学上看，失眠与厚壁菌与拟杆菌的比值变化有关。meta分析显示关键属的变化，包括粪杆菌和毛螺旋体显著减少，蓝杆菌和哈利真杆菌显著增加。肠道菌群的变化也与炎症标志物和代谢紊乱有关。总之，肠道菌群失调与失眠有关，其特征是微生物多样性减少和细菌组成改变。这些发现提示了微生物生物标志物在失眠诊断和分型中的潜在应用，以及个性化微生物群靶向干预措施的发展。

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引用次数: 0

Sleep well, feel well and vice versa? A meta-analysis of daily bidirectional within-person associations between sleep and affect 睡得好，感觉好，反之亦然？一项关于睡眠和情绪之间日常双向关系的元分析

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2026-01-16 DOI: 10.1016/j.smrv.2026.102232

Matthew Bourke , Zoe Harrison , Sally Staton , Kalina Rossa , Simon Smith

This meta-analysis examines the bidirectional within-person association between sleep and affect using data from 118 studies. Focusing on intensive longitudinal designs such as daily diaries and ecological momentary assessments, this meta-analysis examines how daily variations in sleep, measured via subjective and objective methods, are associated with fluctuations in positive and negative affect. Results show small-to-moderate within-person correlations, with better subjective sleep quality and longer sleep duration predicting improved next-day affect. Conversely, more positive affect and less negative affect during the day were modestly associated with better subjective sleep quality but not total sleep time. The within-person correlations were generally stronger when aspects of sleep were self-reported rather than objectively measured, highlighting the importance of perceived sleep experiences. These findings were largely consistent across age groups and health status, suggesting that the relationship between sleep and affect may be universal. Overall, this study underscores the psychological significance of everyday sleep-affect dynamics.

这项荟萃分析利用118项研究的数据，研究了睡眠和情绪之间的双向关系。这项荟萃分析侧重于密集的纵向设计，如日常日记和生态瞬间评估，研究了通过主观和客观方法测量的日常睡眠变化如何与积极和消极影响的波动相关。结果显示，人与人之间存在小到中等程度的相关性，更好的主观睡眠质量和更长的睡眠时间预示着第二天的影响会有所改善。相反，白天更多的积极情绪和更少的消极情绪与更好的主观睡眠质量有一定的关联，但与总睡眠时间无关。当睡眠的各个方面是自我报告而不是客观测量时，个人内部的相关性通常更强，这突出了感知睡眠体验的重要性。这些发现在不同的年龄组和健康状况中基本一致，这表明睡眠和情绪之间的关系可能是普遍存在的。总的来说，这项研究强调了日常睡眠影响动力学的心理学意义。

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引用次数: 0

Unravelling the association between sleep traits and reproductive cancers: A systematic review and meta-analysis 揭示睡眠特征与生殖癌症之间的关系：一项系统回顾和荟萃分析。

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2026-01-13 DOI: 10.1016/j.smrv.2026.102235

Eirini Pagkalidou , Christos K. Papagiannopoulos , Maria Manou , Panagiotis Filis , Rebecca C. Richmond , Konstantinos K. Tsilidis , Georgios Markozannes , Christos V. Chalitsios

Sleep traits (duration, insomnia, chronotype, snoring) are modifiable lifestyle factors that may influence cancer risk, but their association with reproductive cancers remains unclear. We systematically searched PubMed, Scopus, and Web of Science (until 09/2024) for observational studies investigating associations between sleep traits and reproductive cancers (including breast, prostate, endometrial, epithelial ovarian). We extracted estimates from maximally adjusted models and performed random-effects and dose-response meta-analyses. This study included 62 observational studies (45 cohort, 17 case-control) from 55 publications, but cohorts were primarily considered in interpretation. Compared to a morning chronotype, evening chronotype was associated with higher risk of breast cancer (HR = 1.12; 95 %CI: 1.07–1.17; I² = 14 %; 4 cohorts) and epithelial ovarian cancer (HR = 1.15; 95 %CI: 1.02–1.29; I² = 0 %; 2 cohorts). Insomnia was associated with elevated breast cancer risk (RR = 1.23; 95 %CI: 1.01–1.50; I² = 94 %; 9 cohorts), and the association remained similar for diagnosed insomnia (RR = 1.26; 95 %CI: 1.01–1.58; I² = 96 %; 5 studies), but high between-study heterogeneity was observed and the association was lost in properly adjusted studies (RR = 1.04; 95 %CI: 0.95–1.14; I² = 41.5 %; 3 cohorts). These findings support a role for circadian disruption in carcinogenesis. Future research should use objective sleep assessments and evaluate whether modifying sleep behaviours or circadian alignment can reduce cancer risk.

睡眠特征（持续时间、失眠、睡眠类型、打鼾）是可改变的生活方式因素，可能会影响癌症风险，但它们与生殖癌症的关系尚不清楚。我们系统地检索了PubMed、Scopus和Web of Science（截至2024年9月），以调查睡眠特征与生殖癌症（包括乳腺癌、前列腺癌、子宫内膜癌、卵巢上皮癌）之间关系的观察性研究。我们从最大调整模型中提取估计，并进行随机效应和剂量-反应荟萃分析。本研究包括来自55篇出版物的62项观察性研究（45项队列研究，17项病例对照研究），但在解释时主要考虑队列研究。与早晨睡眠类型的人相比，晚上睡眠类型的人患乳腺癌（HR = 1.12; 95% CI: 1.07-1.17; I2 = 14%； 4个队列）和上皮性卵巢癌（HR = 1.15; 95% CI: 1.02-1.29; I2 = 0%； 2个队列）的风险更高。失眠与乳腺癌风险升高相关（RR = 1.23; 95% CI: 1.01-1.50; I2 = 94%； 9个队列），诊断为失眠的患者与失眠之间的关联相似（RR = 1.26; 95% CI: 1.01-1.58; I2 = 96%； 5项研究），但研究间存在较高的异质性，在适当调整的研究中，这种关联消失（RR = 1.04; 95% CI: 0.95-1.14; I2 = 41.5%； 3个队列）。这些发现支持了昼夜节律紊乱在癌变中的作用。未来的研究应该使用客观的睡眠评估，并评估改变睡眠行为或昼夜节律是否可以降低癌症风险。

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引用次数: 0

Advances in sleep research based on the Caenorhabditis elegans: an intestinal microbiota perspective and cutting-edge technology applications 基于秀丽隐杆线虫的睡眠研究进展：肠道微生物群视角和前沿技术应用

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2026-01-13 DOI: 10.1016/j.smrv.2026.102229

Wan-Qi Zhang , Xiao-Lin Li , Rui-Peng Xu , Yu-Long Li , Peng-Fei Hu , Ka-Hing Wong , Zhong-Yang Lin , Qiong-Qiong Yang , Bo-Bo Zhang

Sleep disorders affect approximately 27 % of the global population, driving non-pharmacological research on gut-brain axis regulation. Understanding sleep mechanisms is crucial, given its profound impact on health and disease. Caenorhabditis elegans (C. elegans) offers a powerful model for dissecting fundamental sleep processes, owing to its compact and fully mapped nervous system, genetic tractability, and suitability for high-throughput screening. This review leverages C. elegans integrated with gene editing, high-throughput behavioral phenotyping, and calcium imaging to dissect gut microbiota's role in sleep modulation. We explore how microbial metabolites regulate sleep via gut-brain pathways and summarize conserved sleep-related molecular mechanisms. The purpose of this review is to decode gut-brain-sleep axis interactions, offering novel mechanistic insights into sleep disorder pathophysiology.

睡眠障碍影响了全球约27%的人口，推动了肠-脑轴调节的非药物研究。考虑到睡眠对健康和疾病的深远影响，了解睡眠机制是至关重要的。秀丽隐杆线虫（秀丽隐杆线虫）提供了一个强大的模型，解剖基本的睡眠过程，由于其紧凑和完全映射的神经系统，遗传易感，适合高通量筛选。本综述利用秀丽隐杆线虫整合基因编辑、高通量行为表型和钙成像来解剖肠道微生物群在睡眠调节中的作用。我们探索微生物代谢物如何通过肠-脑通路调节睡眠，并总结保守的睡眠相关分子机制。本综述的目的是解码肠-脑-睡眠轴的相互作用，为睡眠障碍的病理生理学提供新的机制见解。

引用次数: 0

Sleep apnea and substance use: a meta-analysis 睡眠呼吸暂停和物质使用：一项荟萃分析。

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2026-01-07 DOI: 10.1016/j.smrv.2025.102228

Sibylle Mauries , Benjamin Rolland , Justine Frija-Masson , Marie-Pia d’Ortho , Sébastien Catoire , Feriel Zehani , Guillaume Davido , Michel Lejoyeux , Pierre A. Geoffroy

Introduction

Sleep apnea and substance use disorders appear to interact bidirectionally, negatively influencing each other. Obstructive sleep apnea syndrome (OSA) seems particularly prevalent among substance users.

Methods

This meta-analysis aims to evaluate the impact of the most commonly used substances (alcohol, tobacco, cannabis, opioids, and cocaine) on the apnea-hypopnea index (AHI) by comparing the mean AHI scores between users and non-users.

Results

3784 articles were identified from the PubMed search, and 28 studies were included in the meta-analysis. We found a higher AHI among alcohol users (SMD: 0.46, 95 % CI [0.21–0.71] (z = 3.62; p < 0.001)) and a higher prevalence of central sleep apnea among opioid users (SMD: 0.44 95 % CI 0.24–0.64] (z = 4.37; p < 0.001)). The AHI was also elevated among tobacco users, although this difference was not statistically significant. Regarding moderators effects, sex may influence alcohol's impact, while both age and sex could affect the relationship between opioids and AHI. No studies compared the AHI of cocaine users to non-users, and only one study comparing the AHI of cannabis users to non-users were found.

Conclusion

This study highlights the importance of diagnosing and managing sleep apnea in patients with substance use, in order to improve addiction prognosis through specific treatment approaches.

睡眠呼吸暂停和物质使用障碍似乎是双向互动的，相互负向影响。阻塞性睡眠呼吸暂停综合征（OSA）似乎在药物使用者中尤为普遍。方法：本meta分析旨在通过比较使用者和非使用者之间的平均AHI评分，评估最常用物质（酒精、烟草、大麻、阿片类药物和可卡因）对呼吸暂停-低通气指数（AHI）的影响。结果：从PubMed检索中确定了3784篇文章，其中28篇研究被纳入meta分析。我们发现酒精使用者的AHI较高(SMD: 0.46, 95% CI [0.21-0.71] （z = 3.62; p）。结论：本研究强调了药物使用患者诊断和管理睡眠呼吸暂停的重要性，以便通过特定的治疗方法改善成瘾预后。

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引用次数: 0

Hypnosis as therapy for non-REM parasomnia: A literature review 催眠治疗非快速眼动睡眠异常：文献综述

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-12-18 DOI: 10.1016/j.smrv.2025.102227

Geoffroy Solelhac , Nina Rimorini , Chantal Berna , Francesca Siclari

This systematic review provides an overview of the use of medical hypnosis for non-rapid eye movement parasomnias. It aims to describe the hypnotic inductions and suggestions applied in this context and assess their reported effectiveness. From a total of 427 articles identified through a comprehensive search of major medical databases, 24 studies met inclusion criteria. The majority were individual case reports or small case series, with only one study using a controlled design. Across these studies, 348 individuals with non-rapid eye movement parasomnias were described, with 148 receiving treatments with hypnosis. A positive clinical response was reported in approximately 82.6 % of these treated cases. However, the overall quality of evidence was low, with most studies offering limited methodological robustness and lacking standardized outcome measures. The hypnotic induction and suggestion techniques varied widely, yet general suggestions aimed at improving sleep quality were more frequently reported than specific ones targeting parasomnia features. Nevertheless, the more specific suggestions seemed to have better outcomes. This review suggests that hypnosis could be a promising therapeutic option. However, further, well-designed trials are required, including objective outcome evaluation, and standardized, targeted hypnotic approaches developed collaboratively between sleep and hypnosis specialists.

这篇系统的综述提供了对非快速眼动异动症使用医学催眠的概述。它的目的是描述催眠诱导和建议应用在这种情况下，并评估其报告的有效性。通过对主要医学数据库的全面检索，从总共427篇文章中确定，24项研究符合纳入标准。大多数是个案报告或小病例系列，只有一项研究采用对照设计。在这些研究中，348名非快速眼动异动症患者被描述，其中148人接受了催眠治疗。据报道，这些治疗病例中约有82.6%的临床反应为阳性。然而，证据的总体质量较低，大多数研究提供有限的方法稳健性，缺乏标准化的结果测量。催眠诱导和暗示技术差异很大，但旨在改善睡眠质量的一般建议比针对睡眠异常特征的特定建议更频繁地被报道。然而，更具体的建议似乎有更好的结果。这篇综述表明，催眠可能是一种很有前途的治疗选择。然而，进一步需要精心设计的试验，包括客观的结果评估，以及由睡眠和催眠专家合作开发的标准化、有针对性的催眠方法。

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引用次数: 0

Handling Editor: Monica AndersenA global perspective of parent engagement with digital sleep health interventions for young children: A scoping review 家长参与幼儿数字睡眠健康干预的全球视角：范围审查

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-12-13 DOI: 10.1016/j.smrv.2025.102226

Alicia Chung , Laurel Deaton , Jennifer Miller , Ashley Nechyba , Jenny Liu , Menessa Metayer , Tayla von Ash , Michelle Thompson , Shayla K. Shorter , Dorice Vieira , Azizi A. Seixas , Girardin Jean-Louis

Introduction

We examined the landscape of early childhood sleep health interventions that utilized digital tools designed for parents to improve sleep health outcomes during early childhood, (ages 3–8).

Methods

We performed a scoping review of peer-reviewed articles published from inception to April 2025 from the following databases: PubMed, Embase, Web of Science, MEDLINE, Cochrane Library, Engineering Village, Global Health, citation searching, and others. Two medical science librarians conducted the extensive literature search, with strategies detailed at [osf.io/74hba]. This study was guided by the implementation science outcomes framework.

Results

Twenty-one articles met the final inclusion criteria. Included studies reported clinical sleep, behavioral and/or implementation science outcomes. Implementation science outcomes primarily focused on acceptability, appropriateness and feasibility of pediatric digital sleep and family-based tools. Mobile apps were most prominently used, followed by websites and telehealth. Websites contributed to improved child sleep duration, sleep onset, sleep efficiency, daytime sleepiness and reduced night wakings. Mobile apps reported the aforementioned child sleep outcomes, as well as improvements in parent mental health and daytime functioning.

Conclusions

Digital sleep health tools have the potential to ameliorate sleep problems in young children. Digital interventions may improve sleep and wellbeing in the family unit.

前言：我们研究了儿童早期睡眠健康干预措施的现状，这些干预措施利用为父母设计的数字工具来改善儿童早期（3-8岁）的睡眠健康结果。方法我们对从成立到2025年4月发表的同行评议文章进行了范围审查，这些文章来自以下数据库：PubMed、Embase、Web of Science、MEDLINE、Cochrane Library、Engineering Village、Global Health、引文搜索等。两位医学图书管理员进行了广泛的文献检索，详细策略见[osf.io/74hba]。本研究以实施科学成果框架为指导。结果21篇文章符合最终纳入标准。纳入的研究报告了临床睡眠、行为和/或实施科学的结果。实施科学成果主要集中在儿童数字睡眠和基于家庭的工具的可接受性、适当性和可行性上。使用最多的是移动应用程序，其次是网站和远程医疗。网站有助于改善儿童的睡眠时间、睡眠开始、睡眠效率、白天嗜睡和减少夜间醒来。移动应用程序报告了上述儿童的睡眠结果，以及父母心理健康和白天功能的改善。结论数字睡眠健康工具具有改善幼儿睡眠问题的潜力。数字干预可能会改善家庭的睡眠和健康。

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引用次数: 0