Sleep Medicine Reviews最新文献

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Hypnosis as therapy for non-REM parasomnia: A literature review 催眠治疗非快速眼动睡眠异常：文献综述

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-12-18 DOI: 10.1016/j.smrv.2025.102227

Geoffroy Solelhac , Nina Rimorini , Chantal Berna , Francesca Siclari

This systematic review provides an overview of the use of medical hypnosis for non-rapid eye movement parasomnias. It aims to describe the hypnotic inductions and suggestions applied in this context and assess their reported effectiveness. From a total of 427 articles identified through a comprehensive search of major medical databases, 24 studies met inclusion criteria. The majority were individual case reports or small case series, with only one study using a controlled design. Across these studies, 348 individuals with non-rapid eye movement parasomnias were described, with 148 receiving treatments with hypnosis. A positive clinical response was reported in approximately 82.6 % of these treated cases. However, the overall quality of evidence was low, with most studies offering limited methodological robustness and lacking standardized outcome measures. The hypnotic induction and suggestion techniques varied widely, yet general suggestions aimed at improving sleep quality were more frequently reported than specific ones targeting parasomnia features. Nevertheless, the more specific suggestions seemed to have better outcomes. This review suggests that hypnosis could be a promising therapeutic option. However, further, well-designed trials are required, including objective outcome evaluation, and standardized, targeted hypnotic approaches developed collaboratively between sleep and hypnosis specialists.

这篇系统的综述提供了对非快速眼动异动症使用医学催眠的概述。它的目的是描述催眠诱导和建议应用在这种情况下，并评估其报告的有效性。通过对主要医学数据库的全面检索，从总共427篇文章中确定，24项研究符合纳入标准。大多数是个案报告或小病例系列，只有一项研究采用对照设计。在这些研究中，348名非快速眼动异动症患者被描述，其中148人接受了催眠治疗。据报道，这些治疗病例中约有82.6%的临床反应为阳性。然而，证据的总体质量较低，大多数研究提供有限的方法稳健性，缺乏标准化的结果测量。催眠诱导和暗示技术差异很大，但旨在改善睡眠质量的一般建议比针对睡眠异常特征的特定建议更频繁地被报道。然而，更具体的建议似乎有更好的结果。这篇综述表明，催眠可能是一种很有前途的治疗选择。然而，进一步需要精心设计的试验，包括客观的结果评估，以及由睡眠和催眠专家合作开发的标准化、有针对性的催眠方法。

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引用次数: 0

Handling Editor: Monica AndersenA global perspective of parent engagement with digital sleep health interventions for young children: A scoping review 家长参与幼儿数字睡眠健康干预的全球视角：范围审查

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-12-13 DOI: 10.1016/j.smrv.2025.102226

Alicia Chung , Laurel Deaton , Jennifer Miller , Ashley Nechyba , Jenny Liu , Menessa Metayer , Tayla von Ash , Michelle Thompson , Shayla K. Shorter , Dorice Vieira , Azizi A. Seixas , Girardin Jean-Louis

Introduction

We examined the landscape of early childhood sleep health interventions that utilized digital tools designed for parents to improve sleep health outcomes during early childhood, (ages 3–8).

Methods

We performed a scoping review of peer-reviewed articles published from inception to April 2025 from the following databases: PubMed, Embase, Web of Science, MEDLINE, Cochrane Library, Engineering Village, Global Health, citation searching, and others. Two medical science librarians conducted the extensive literature search, with strategies detailed at [osf.io/74hba]. This study was guided by the implementation science outcomes framework.

Results

Twenty-one articles met the final inclusion criteria. Included studies reported clinical sleep, behavioral and/or implementation science outcomes. Implementation science outcomes primarily focused on acceptability, appropriateness and feasibility of pediatric digital sleep and family-based tools. Mobile apps were most prominently used, followed by websites and telehealth. Websites contributed to improved child sleep duration, sleep onset, sleep efficiency, daytime sleepiness and reduced night wakings. Mobile apps reported the aforementioned child sleep outcomes, as well as improvements in parent mental health and daytime functioning.

Conclusions

Digital sleep health tools have the potential to ameliorate sleep problems in young children. Digital interventions may improve sleep and wellbeing in the family unit.

前言：我们研究了儿童早期睡眠健康干预措施的现状，这些干预措施利用为父母设计的数字工具来改善儿童早期（3-8岁）的睡眠健康结果。方法我们对从成立到2025年4月发表的同行评议文章进行了范围审查，这些文章来自以下数据库：PubMed、Embase、Web of Science、MEDLINE、Cochrane Library、Engineering Village、Global Health、引文搜索等。两位医学图书管理员进行了广泛的文献检索，详细策略见[osf.io/74hba]。本研究以实施科学成果框架为指导。结果21篇文章符合最终纳入标准。纳入的研究报告了临床睡眠、行为和/或实施科学的结果。实施科学成果主要集中在儿童数字睡眠和基于家庭的工具的可接受性、适当性和可行性上。使用最多的是移动应用程序，其次是网站和远程医疗。网站有助于改善儿童的睡眠时间、睡眠开始、睡眠效率、白天嗜睡和减少夜间醒来。移动应用程序报告了上述儿童的睡眠结果，以及父母心理健康和白天功能的改善。结论数字睡眠健康工具具有改善幼儿睡眠问题的潜力。数字干预可能会改善家庭的睡眠和健康。

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引用次数: 0

Time to take the Declaration of Helsinki seriously? A systematic review of comparison conditions in clinical trials on internet-delivered cognitive behavioral therapy for insomnia 是时候认真对待《赫尔辛基宣言》了？网络认知行为治疗失眠症临床试验比较条件的系统回顾

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-12-11 DOI: 10.1016/j.smrv.2025.102224

Lorenz Grolig , Hanna Brückner , Hannah Heimes , Claudia Buntrock , Christin Hempeler , Kai Spiegelhalder , Dirk Lehr

The Declaration of Helsinki (DoH) provides guidance on the choice of comparators in clinical trials, stating that new treatments must be compared against the best proven treatment. This systematic review examines whether research on a new treatment – internet-delivered cognitive behavioral therapy for insomnia (iCBT-I) – has adhered to these DoH requirements. A systematic literature search for randomized controlled trials (RCTs) testing iCBT-I in clinical samples was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. To identify the gold standard treatment, national guidelines were analyzed for all countries where published research on iCBT-I had been conducted.

After screening, 32 RCTs and seven guidelines for 12 countries were included. Almost all guidelines recommend face-to-face CBT-I as the gold standard, but only four (12.5 %) of the RCTs used this gold standard as a comparator. None of the other trials explained why they did not follow the DoH's recommendation.

The majority of clinical trials did not compare iCBT-I against the gold standard. As the DoH is intended to guide clinical research ethics, this low level of adherence is remarkable, and it raises uncertainty for patients, therapists, and policymakers about the effectiveness of iCBT-I compared to the gold standard treatment.

《赫尔辛基宣言》（DoH）为临床试验中比较物的选择提供了指导，指出必须将新治疗方法与已证实的最佳治疗方法进行比较。这篇系统综述研究了一种新的治疗方法——互联网传递的失眠认知行为疗法（iCBT-I）——是否符合这些DoH要求。按照系统评价和荟萃分析的首选报告项目（PRISMA）指南，对临床样本中检测iCBT-I的随机对照试验（rct）进行了系统文献检索。为了确定金标准治疗，对已发表icbt - 1研究的所有国家的国家指南进行了分析。筛选后，纳入了12个国家的32项随机对照试验和7项指南。几乎所有的指南都推荐面对面的CBT-I作为金标准，但只有四个（12.5%）的随机对照试验使用这一金标准作为比较。其他试验都没有解释为什么他们没有遵循卫生部的建议。大多数临床试验没有将iCBT-I与黄金标准进行比较。由于DoH旨在指导临床研究伦理，这种低水平的依从性是值得注意的，它给患者、治疗师和政策制定者带来了与金标准治疗相比iCBT-I有效性的不确定性。

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引用次数: 0

Does short- and long-term exposure to air pollution affect the risk of obstructive sleep apnea? A systematic review and meta-analysis 短期和长期暴露在空气污染中会影响阻塞性睡眠呼吸暂停的风险吗？系统回顾和荟萃分析

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-12-11 DOI: 10.1016/j.smrv.2025.102225

Yansu He , Shuting Wang , Tianhang Zhang , Yuxuan Gu , Zuyao Yang , Linying Wu , Kin Fai Ho

The contribution of air pollution to obstructive sleep apnea (OSA) remains unclear. This systematic review and meta-analysis evaluated the impact of air pollution across different exposure windows on OSA and examined effect modifiers. Pubmed, Web of Science, and Embase were searched from inception to September 2024. Meta-analyses synthesized risk estimates using fixed- or random-effects models with I² heterogeneity assessment. Certainty of evidence was assessed using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach. Of 5196 potential papers, 20 studies were included, with 13 eligible for meta-analysis. High-certainty evidence indicated that each 10 μg/m³ increase in short- and long-term PM_2.5 exposure was associated with a 2.25 % (95 % CI: 1.10 to 3.41) and 13.33 % (95 % CI: 9.85 to 16.80) increase in apnea-hypopnea index (AHI), respectively. For NO₂, each 10 ppb increase in short- and long-term exposure was associated with a 2.92 % (95 % CI: 1.29 to 4.54) and 8.93 % (95 % CI: 2.06 to 15.79) increase in AHI, with high- and moderate-certainty evidence, respectively. Medium-term PM_2.5 and NO₂ exposure were also associated with AHI, although with low certainty. No significant associations were observed for PM₁₀ and O₃. Exposure to PM_2.5 and NO₂, but not PM₁₀ or O₃, was associated with OSA severity.

空气污染对阻塞性睡眠呼吸暂停（OSA）的影响尚不清楚。本系统综述和荟萃分析评估了不同暴露窗口的空气污染对OSA的影响，并检查了影响调节剂。Pubmed， Web of Science和Embase从成立到2024年9月进行了搜索。荟萃分析使用固定或随机效应模型综合风险估计，并进行I2异质性评估。证据的确定性采用GRADE（建议评估、发展和评价分级）方法进行评估。在5196篇潜在论文中，纳入了20篇研究，其中13篇符合meta分析的条件。高确定性证据表明，短期和长期PM2.5暴露每增加10 μg/m3，呼吸暂停低通气指数（AHI）分别增加2.25% （95% CI: 1.10至3.41）和13.33% （95% CI: 9.85至16.80）。对于二氧化氮，短期和长期暴露每增加10 ppb， AHI分别增加2.92% （95% CI: 1.29至4.54）和8.93% (95% CI: 2.06至15.79)，具有高确定性和中等确定性的证据。中期PM2.5和NO2暴露也与AHI相关，尽管确定性较低。PM10和O3没有明显的相关性。暴露于PM2.5和NO2，而不是PM10或O3，与OSA严重程度相关。

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引用次数: 0

OSA, CPAP, and the impact on cardiometabolic parameters: what is next? OSA、CPAP和对心脏代谢参数的影响：下一步是什么？

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-12-01 DOI: 10.1016/j.smrv.2025.102213

Luciano F. Drager

引用次数: 0

Forecasting the burden of insomnia: A call to action 预测失眠的负担：行动的呼吁

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-12-01 DOI: 10.1016/j.smrv.2025.102211

Wenxin Bao, Rong Ren, Xiangdong Tang, Ye Zhang

引用次数: 0

Artificial intelligence and sleep medicine II: A scoping review of applications, advancements, and future directions 人工智能和睡眠医学II：应用、进展和未来方向的范围审查。

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-11-28 DOI: 10.1016/j.smrv.2025.102212

Haitham Jahrami , Waqar Husain , Khaled Trabelsi , Thomas Penzel , Max Hirshkowitz , Javad Razjouyan , Ahmed S. BaHammam , Amir Sharafkhaneh

Background

Artificial intelligence (AI) has rapidly advanced in sleep medicine, offering innovative solutions for sleep disorder management. The integration of AI technologies presents unprecedented opportunities to address longstanding challenges in diagnosis, monitoring, and treatment.

Methods

This scoping review summarizes current AI applications in sleep medicine following PRISMA-ScR. A comprehensive search was conducted across various databases from inception to 2024, following PRISMA-ScR guidelines. Eligible studies included original AI research, systematic reviews, and meta-analyses focusing on sleep medicine.

Results

AI models for obstructive sleep apnea (OSA) detection demonstrated accuracy between 85 % and 99 % in controlled settings, with outlier up to 99.9 %. Deep learning approaches for sleep staging and quality assessment match human expert performance. AI applications have extended to other disorders like insomnia and narcolepsy. Wearable technologies and non-contact sensors enable continuous monitoring outside laboratory settings, with some achieving sensitivity >96 % and specificity >97 % for OSA detection. Significant real-world validation gaps persist.

Conclusions

While AI shows transformative potential in sleep medicine, implementation challenges remain. Future research should prioritize multicenter validation, ethical governance, and culturally inclusive AI frameworks to ensure safe and equitable clinical translation. Addressing ethical considerations and standardizing methodological reporting are essential for widespread adoption of these technologies in clinical practice.

背景：人工智能（AI）在睡眠医学领域迅速发展，为睡眠障碍管理提供了创新的解决方案。人工智能技术的整合为解决诊断、监测和治疗方面的长期挑战提供了前所未有的机遇。方法：本文综述了prism - scr后人工智能在睡眠医学中的应用现状。根据PRISMA-ScR指南，从成立到2024年，在各种数据库中进行了全面的搜索。符合条件的研究包括原始的人工智能研究、系统综述和关注睡眠医学的荟萃分析。结果：用于阻塞性睡眠呼吸暂停（OSA）检测的人工智能模型在受控环境下的准确率在85%至99%之间，异常值高达99.9%。深度学习的睡眠分期和质量评估方法与人类专家的表现相匹配。人工智能的应用已经扩展到失眠和嗜睡症等其他疾病。可穿戴技术和非接触式传感器可以在实验室环境之外进行连续监测，其中一些检测OSA的灵敏度为bbbb96 %，特异性为bbbb97 %。显著的现实验证差距仍然存在。结论：虽然人工智能在睡眠医学中显示出变革潜力，但实施方面的挑战仍然存在。未来的研究应优先考虑多中心验证、伦理治理和文化包容性的人工智能框架，以确保安全和公平的临床翻译。解决伦理问题和标准化方法报告是在临床实践中广泛采用这些技术的必要条件。

{"title":"Artificial intelligence and sleep medicine II: A scoping review of applications, advancements, and future directions","authors":"Haitham Jahrami , Waqar Husain , Khaled Trabelsi , Thomas Penzel , Max Hirshkowitz , Javad Razjouyan , Ahmed S. BaHammam , Amir Sharafkhaneh","doi":"10.1016/j.smrv.2025.102212","DOIUrl":"10.1016/j.smrv.2025.102212","url":null,"abstract":"<div><h3>Background</h3><div>Artificial intelligence (AI) has rapidly advanced in sleep medicine, offering innovative solutions for sleep disorder management. The integration of AI technologies presents unprecedented opportunities to address longstanding challenges in diagnosis, monitoring, and treatment.</div></div><div><h3>Methods</h3><div>This scoping review summarizes current AI applications in sleep medicine following PRISMA-ScR. A comprehensive search was conducted across various databases from inception to 2024, following PRISMA-ScR guidelines. Eligible studies included original AI research, systematic reviews, and meta-analyses focusing on sleep medicine.</div></div><div><h3>Results</h3><div>AI models for obstructive sleep apnea (OSA) detection demonstrated accuracy between 85 % and 99 % in controlled settings, with outlier up to 99.9 %. Deep learning approaches for sleep staging and quality assessment match human expert performance. AI applications have extended to other disorders like insomnia and narcolepsy. Wearable technologies and non-contact sensors enable continuous monitoring outside laboratory settings, with some achieving sensitivity >96 % and specificity >97 % for OSA detection. Significant real-world validation gaps persist.</div></div><div><h3>Conclusions</h3><div>While AI shows transformative potential in sleep medicine, implementation challenges remain. Future research should prioritize multicenter validation, ethical governance, and culturally inclusive AI frameworks to ensure safe and equitable clinical translation. Addressing ethical considerations and standardizing methodological reporting are essential for widespread adoption of these technologies in clinical practice.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"85 ","pages":"Article 102212"},"PeriodicalIF":9.7,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insomnia among hospitalized inpatients: A systematic review and network meta-analysis 住院患者失眠：系统回顾与网络荟萃分析

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-11-22 DOI: 10.1016/j.smrv.2025.102210

Dario Bottignole , Giulia Balella , Matteo Minetti , Luca Gambolò , Francesco Rausa , Giorgio Ughetti , Andrea Melpignano , Marcello Giuseppe Maggio , Liborio Parrino , Carlotta Mutti

Insomnia affects up to 50% of hospitalized patients and is strongly associated with longer hospital stays and higher mortality rates, especially among vulnerable individuals. Despite its prevalence, it's often overlooked in clinical practice and research. Our systematic review analyzed and compared pharmacological interventions for insomnia in hospitalized patients. We searched five major databases for randomized controlled trials published before January 2024. A total of 29 trials (1913 patients, mean age 58.4 ± 9.66) were finally included. Different drug classes were evaluated, including benzodiazepines, Z-drugs, melatonin receptor agonists, antidepressants, antihistamines, alpha-2 adrenergic agonists, and dietary supplements. We conducted a network meta-analysis on drugs' efficacy across subjective sleep quality, sleep latency, total sleep duration, and nocturnal awakenings. Notably, only a minority of studies focused on fragile populations, such as geriatric and critically ill patients. Results are also discussed according to potential moderating factors (i.e., gender, age, admission setting). Our review provides a framework for the pharmacologic treatment of insomnia disorder in inpatients. Differences in study methodologies limit the generalizability of findings, highlighting the urgent need for standardized research to fill existing gaps. We therefore propose a concise protocol to guide the design of future studies on this clinically important topic.

多达50%的住院患者患有失眠症，失眠与住院时间较长和死亡率较高密切相关，尤其是在脆弱人群中。尽管它很普遍，但在临床实践和研究中经常被忽视。我们的系统综述分析并比较了住院患者失眠的药物干预。我们在五个主要数据库中检索了2024年1月之前发表的随机对照试验。最终纳入29项试验（1913例，平均年龄58.4±9.66岁）。评估了不同的药物类别，包括苯二氮卓类药物、z型药物、褪黑激素受体激动剂、抗抑郁药、抗组胺药、α -2肾上腺素能激动剂和膳食补充剂。我们对药物在主观睡眠质量、睡眠潜伏期、总睡眠时间和夜间觉醒方面的疗效进行了网络荟萃分析。值得注意的是，只有少数研究关注脆弱人群，如老年人和危重病人。结果还根据潜在的调节因素（即性别、年龄、入院环境）进行了讨论。我们的综述为住院患者失眠的药物治疗提供了一个框架。研究方法的差异限制了研究结果的普遍性，强调了标准化研究填补现有空白的迫切需要。因此，我们提出了一个简明的方案来指导这一临床重要课题的未来研究设计。

{"title":"Insomnia among hospitalized inpatients: A systematic review and network meta-analysis","authors":"Dario Bottignole , Giulia Balella , Matteo Minetti , Luca Gambolò , Francesco Rausa , Giorgio Ughetti , Andrea Melpignano , Marcello Giuseppe Maggio , Liborio Parrino , Carlotta Mutti","doi":"10.1016/j.smrv.2025.102210","DOIUrl":"10.1016/j.smrv.2025.102210","url":null,"abstract":"<div><div>Insomnia affects up to 50% of hospitalized patients and is strongly associated with longer hospital stays and higher mortality rates, especially among vulnerable individuals. Despite its prevalence, it's often overlooked in clinical practice and research. Our systematic review analyzed and compared pharmacological interventions for insomnia in hospitalized patients. We searched five major databases for randomized controlled trials published before January 2024. A total of 29 trials (1913 patients, mean age 58.4 ± 9.66) were finally included. Different drug classes were evaluated, including benzodiazepines, Z-drugs, melatonin receptor agonists, antidepressants, antihistamines, alpha-2 adrenergic agonists, and dietary supplements. We conducted a network meta-analysis on drugs' efficacy across subjective sleep quality, sleep latency, total sleep duration, and nocturnal awakenings. Notably, only a minority of studies focused on fragile populations, such as geriatric and critically ill patients. Results are also discussed according to potential moderating factors (i.e., gender, age, admission setting). Our review provides a framework for the pharmacologic treatment of insomnia disorder in inpatients. Differences in study methodologies limit the generalizability of findings, highlighting the urgent need for standardized research to fill existing gaps. We therefore propose a concise protocol to guide the design of future studies on this clinically important topic.</div></div>","PeriodicalId":49513,"journal":{"name":"Sleep Medicine Reviews","volume":"85 ","pages":"Article 102210"},"PeriodicalIF":9.7,"publicationDate":"2025-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145625383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementing strategies to address the global burden of insomnia 实施解决全球失眠负担的战略

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-11-22 DOI: 10.1016/j.smrv.2025.102209

Adam V. Benjafield , Emerson M. Wickwire

引用次数: 0

Sleep, cognition, and electrophysiology: Intersecting pathways in childhood cancer 睡眠、认知和电生理：儿童癌症的交叉通路。

IF 9.7 1区医学 Q1 CLINICAL NEUROLOGY

Sleep Medicine Reviews

Pub Date : 2025-11-22 DOI: 10.1016/j.smrv.2025.102205

Andrea Sanchez-Corzo , Zachary Loschinskey , Miguel Navarrete , Catalina A. Saini Ferron , Pankaj Pandey , Jesyin Lai , Belinda N. Mandrell , Zachary R. Abramson , Valerie McLaughlin Crabtree , Ranganatha Sitaram

Survivors of pediatric cancer are at high risk of long-term cognitive dysfunction. This problem is exacerbated as this population often reports poor sleep quality, which can negatively affect well-being. Sleep-related brain activity is known to influence cognitive development by regulating memory consolidation and cognitive functioning. However, the differences in sleep-related brain activity between healthy controls and pediatric cancer survivors are unclear. This review examines how sleep disturbances and cognitive impairments converge in survivors of childhood cancer, and proposes electrophysiology as a possible mechanistic bridge between these domains. We synthesize what is known from the general population and pediatric samples, highlight the critical need to investigate electrophysiological anomalies in pediatric cancer survivors, and suggest that neuromodulation techniques such as transcranial direct stimulation, transcranial magnetic stimulation, and sensory stimulation may be viable therapeutic interventions to enhance both sleep quality and cognitive function once possible anomalies are characterized in this population. Our review emphasizes the need for additional research to understand the complex relationship between sleep and cognition in pediatric cancer survivors to improve patient care and quality of life.

儿童癌症的幸存者长期认知功能障碍的风险很高。由于这一人群经常报告睡眠质量差，这可能会对健康产生负面影响，所以这个问题更加严重。众所周知，睡眠相关的大脑活动通过调节记忆巩固和认知功能来影响认知发展。然而，健康对照组和儿童癌症幸存者之间睡眠相关的大脑活动的差异尚不清楚。这篇综述探讨了睡眠障碍和认知障碍如何在儿童癌症幸存者中汇合，并提出电生理学作为这些领域之间可能的机制桥梁。我们综合了一般人群和儿童样本的已知信息，强调了研究儿童癌症幸存者电生理异常的迫切需要，并建议神经调节技术，如经颅直接刺激、经颅磁刺激和感觉刺激，一旦在这一人群中发现可能的异常特征，可能是提高睡眠质量和认知功能的可行治疗干预措施。我们的综述强调需要进一步的研究来了解儿童癌症幸存者睡眠和认知之间的复杂关系，以改善患者的护理和生活质量。

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