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Legal obstacles jeopardise research in personalised medicine - experiences from a Nordic collaboration within rheumatology. 法律障碍危及个体化医学研究——来自北欧风湿病学合作的经验。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1177/14034948231212711
Bente Glintborg, Mats Hansson, Hilde Berner Hammer, Lars Klareskog, Saedis Saevarsdottir, Helga Westerlind, Johan Rönnelid, Isabel Gehring, Mikael Benson, Bente Appel Esbensen, Merete Lund Hetland, Leonid Padyukov, Tue Wenzel Kragstrup, Ellen-Margrethe Hauge, Barbara Bislawska AxnÄs, Niels Steen Krogh, Martina Johannesson, Johan Askling

Aims: Personalised medicine in chronic complex diseases such as rheumatoid arthritis (RA) is within reach but requires international multi-stakeholder collaboration. We exemplify how national implementations of the General Data Protection Regulation (GDPR) have introduced administrative delays and created disincentives for data sharing and collaborative research.

Methods: Our Danish/Swedish/Norwegian research collaboration (the 3-year NordForsk-funded "NORA" project) aims to develop a personalised medicine approach for the management of RA, built on the exploitation of unique existing data sources: longitudinal data from clinical rheumatology registries, research cohorts, nationwide health care registries, and biobank material from >20 sample collections. Data and results are shared and accessed remotely by collaborators at secure servers. New biomarker assays and patient-centric implementations of the results are to be explored, validated, and disseminated to patients and health care via the development of digital tools.

Results: Following the advice of legal experts at the involved academic or public institutions and private companies, GDPR compliance resulted in >20 legal documents to govern the collaboration (consortium-, joint controller-, research collaboration-, data sharing-, and a series of unique two-way data processing-, and material transfer agreements). Lack of agreed-upon templates, policies, procedures, and a shortage of legal resources have caused considerable delays. Thus, our research consortium has spent more time ensuring GDPR compliance than on actual research activities.

Conclusions: The current interpretation and implementation of the legal premises (rather than the GDPR per se) for research collaborations caused unnecessary barriers and delays. Our experiences call for Nordic trust-based code-of-conduct-like framework agreements, and for harmonisation of procedures and templates, lest the Nordic advantage in research be lost.

目标:类风湿关节炎(RA)等慢性复杂疾病的个体化治疗是可以实现的,但需要国际多方利益相关者的合作。我们举例说明了《通用数据保护条例》(GDPR)的国家实施如何导致行政延误,并对数据共享和合作研究造成阻碍。方法:我们的丹麦/瑞典/挪威研究合作(为期3年的nordforsk资助的“NORA”项目)旨在开发一种用于RA管理的个性化医学方法,建立在利用独特的现有数据源的基础上:来自临床风湿病登记处的纵向数据,研究队列,全国卫生保健登记处,以及来自bbb20样本收集的生物库材料。数据和结果由安全服务器上的协作者远程共享和访问。新的生物标志物分析和以患者为中心的结果实施将被探索、验证,并通过数字工具的开发传播给患者和医疗保健。结果:根据相关学术或公共机构和私营公司法律专家的建议,GDPR合规导致了bbbb20个法律文件来管理合作(财团-,联合控制器-,研究合作-,数据共享-以及一系列独特的双向数据处理-和材料转让协议)。缺乏商定的模板、政策、程序和缺乏法律资源造成了相当大的延误。因此,我们的研究联盟花费了比实际研究活动更多的时间来确保GDPR合规性。结论:目前对研究合作的法律前提(而不是GDPR本身)的解释和实施造成了不必要的障碍和延误。我们的经验要求北欧建立以信任为基础的类似行为准则的框架协议,并协调程序和模板,以免北欧在研究方面的优势丧失。
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引用次数: 0
Geographical variation in quality-adjusted life expectancy in the North Denmark Region. 北丹麦地区质量调整预期寿命的地理差异。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1177/14034948241298986
Jakob Juul Christensen, Cathrine Elgaard Jensen, Sabine Michelsen Raunbak, Sabrina Storgaard Sørensen, Jan Sørensen

Objective: This study examined the geographical variations in quality-adjusted life expectancy (QALE) in the North Denmark Region.

Methods: QALE was used to measure health expectancy within each municipality of the North Denmark Region. Measures of health-related quality of life (HRQoL) were obtained from a representative sample of 19,598 responses to the EQ-5D-5L questionnaire in the 2021 regional health survey. Abridged periodic life tables were constructed using mortality data from Statistics Denmark stratified by age, sex, and municipality. The stepwise replacement algorithm developed by Andreev et al. was applied to decompose QALE into its mortality and HRQoL components and investigate the main drivers of the QALE variations between municipalities.

Results: The regional average QALE at 16 years of age was 52.6 quality-adjusted life years (QALYs) (95% CI: 52.1-53.0) for men and 53.1 QALYs (95% CI: 52.7-53.5) for women. No statistically significant variations in QALE were found between municipalities. Comparing the highest and lowest scoring municipalities for males, Rebild had 54.5 QALY (95% CI: 51.7-57.2) while Hjørring had 51.9 QALY (95% CI: 49.9-54.1), showing a variation of 2.57 QALE driven by higher HRQoL scores and lower mortality rates. For females, Rebild had 54.3 QALY (95% CI: 52.1-56.5) and Vesthimmerland had 51.3 QALY (95% CI: 49.1-53.4), showing a variation of 3.03 QALE, mostly driven by increased HRQoL scores and to some extent lower mortality rates.

Conclusions: Variations in QALE, although not statistically significant, existed between the municipalities in the North Denmark Region. Further research should explore the reasons for these variations to inspire future policy development.

目的:本研究考察了北丹麦地区质量调整预期寿命(QALE)的地理差异。方法:采用质量加权指数(QALE)测量北丹麦地区各城市的健康预期。从2021年区域健康调查中对EQ-5D-5L问卷的19,598个代表性样本中获得了与健康相关的生活质量(HRQoL)的测量值。使用丹麦统计局按年龄、性别和城市分层的死亡率数据构建了缩短周期生命表。采用Andreev等人开发的逐步替代算法,将QALE分解为死亡率和HRQoL两个分量,研究城市间QALE差异的主要驱动因素。结果:16岁时区域平均QALE男性为52.6质量调整生命年(QALYs) (95% CI: 52.1-53.0),女性为53.1 QALYs (95% CI: 52.7-53.5)。不同城市间的QALE没有统计学上的显著差异。比较男性得分最高和最低的城市,Rebild的QALY为54.5 (95% CI: 51.7-57.2),而hjorring的QALY为51.9 (95% CI: 49.9-54.1),显示由较高的HRQoL得分和较低的死亡率驱动的QALE变异为2.57。对于女性,Rebild的QALY为54.3 (95% CI: 52.1-56.5), Vesthimmerland的QALY为51.3 (95% CI: 49.1-53.4), QALE的变化为3.03,主要是由于HRQoL评分的增加和一定程度上较低的死亡率。结论:在北丹麦地区的城市之间,QALE存在差异,尽管没有统计学意义。进一步的研究应探讨这些差异的原因,以启发未来的政策制定。
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引用次数: 0
Preschool-level socio-economic deprivation in relation to emotional and behavioural problems among preschool children in Sweden. 瑞典学龄前社会经济贫困与学龄前儿童情绪和行为问题的关系。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 Epub Date: 2024-01-02 DOI: 10.1177/14034948231218040
Natalie Durbeej, Richard Ssegonja, Raziye Salari, Anton Dahlberg, Helena Fabian, Anna Sarkadi

Aims: The aim of this study was to explore the association between preschool-level socio-economic deprivation and emotional and behavioural problems among preschool children in Sweden using a multilevel approach.

Methods: In this cross-sectional study, we used data on 2267 children whose parents and preschool teachers had responded to items measuring individual-level socio-economic deprivation and the Strengths and Difficulties Questionnaire (SDQ) for assessment of emotional and behavioural problems. Further, the Socioeconomic Structure Compensation Index (SSCI), collected from Uppsala municipality, was used to assess preschool-level socio-economic deprivation. Unadjusted and adjusted multilevel logistic regression models were used to explore the relations between preschool-level socio-economic deprivation and emotional and behavioural problems.

Results: In unadjusted models, children who attended preschools classified as highly deprived had elevated odds for emotional symptoms (odds ratio (OR) 1.71) as rated by parents. However, this association did not remain significant after adjusting for individual-level socio-economic deprivation factors. In both unadjusted and adjusted models, children who attended preschools classified as moderately deprived had elevated odds for peer-relationship problems as rated by parents (OR 1.63; adjusted OR 1.48). There were no significant associations between preschool deprivation and emotional and behavioural problems as rated by preschool teachers.

Conclusions: Swedish preschools may have a compensatory capacity in addressing children's emotional and behavioural problems, whereas preschool-level deprivation remained significantly associated with peer-relationship problems after controlling for individual-level socio-economic deprivation factors. This implies that peer-relationship problems in deprived preschools need to be addressed in a broader community context.

目的:本研究旨在采用多层次方法探讨瑞典学龄前社会经济贫困与学龄前儿童情绪和行为问题之间的关系:在这项横断面研究中,我们使用了 2267 名儿童的数据,这些儿童的父母和学前班教师回答了衡量个人社会经济贫困程度的项目以及用于评估情绪和行为问题的优势与困难问卷(SDQ)。此外,从乌普萨拉市收集的社会经济结构补偿指数(SSCI)也用于评估学龄前儿童的社会经济贫困程度。研究采用未经调整和调整的多层次逻辑回归模型来探讨学龄前社会经济贫困与情绪和行为问题之间的关系:在未经调整的模型中,在被归类为高度贫困的学龄前学校就读的儿童出现家长所评定的情绪症状的几率较高(几率比(OR)1.71)。然而,在调整了个人层面的社会经济贫困因素后,这种关联并不显著。在未调整和调整后的模型中,就读于中度贫困学前班的儿童出现家长评定的同伴关系问题的几率较高(OR1.63;调整后的OR1.48)。学前教育机构的贫困程度与学前教育机构教师评定的情绪和行为问题之间没有明显关联: 瑞典学前教育机构在解决儿童的情绪和行为问题方面可能具有补偿能力,而在控制了个人层面的社会经济贫困因素后,学前教育机构的贫困程度仍与同伴关系问题有明显关联。这意味着,贫困学龄前学校中的同伴关系问题需要在更广泛的社区背景下加以解决。
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引用次数: 0
Projected health benefits of air pollution reductions in a Swedish population. 减少空气污染对瑞典人口的健康影响预测。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-26 DOI: 10.1177/14034948241264099
Anna Oudin, Erin Flanagan, Bertil Forsberg

Background: A large part of the Swedish population is exposed to higher levels of air pollution than the health-centered air quality guidelines recommended by the World Health Organization (WHO).

Aim: The aim of the study was to illustrate the potential health benefits of cleaner air in Sweden by conducting a comprehensive health impact assessment, using a population sample of 100,000 individuals representing the country's demographics.

Methods: Exposure-response functions for various health outcomes were derived from epidemiological literature, mainly from systematic reviews and low-exposure settings. Two hypothetical scenarios were studied: a 1 µg/m3 decrease in particulate matter with an aerodynamic diameter <2.5µm (PM2.5) and nitrogen dioxide (NO2), and a reduction in PM2.5 or NO2 from average exposure corresponding to Sweden's Clean Air objectives to WHO's air quality guidelines.

Results: The findings demonstrated that even a modest decrease in air pollution concentrations can yield significant health benefits. For example, reducing PM2.5 by 1 µg/m3 was projected to correspond to a 1% to 2% decrease in mortality, a 2% reduction in myocardial infarction cases, a 4% decrease in stroke incidence, a 2% decline in chronic obstructive pulmonary disease, and a 1% decreases in lung cancer and type 2 diabetes annually. Moreover, this reduction is estimated to lower childhood asthma cases, incidences of hypertension during pregnancy, and premature births by 3%, 3% and 2%, respectively, each year.

Conclusions: The results highlighted that even minor enhancements in air quality would lead to substantial improvements in public health.

背景:目的:本研究的目的是利用代表瑞典人口结构的 10 万个人口样本,通过开展全面的健康影响评估,说明瑞典更清洁空气对健康的潜在益处:方法:从流行病学文献中得出了各种健康结果的暴露-反应函数,这些文献主要来自系统综述和低暴露环境。研究了两种假设情况:空气动力学直径为 2.5 的颗粒物和二氧化氮(NO2)减少 1 µg/m3,PM2.5 或 NO2 的平均暴露量从瑞典的清洁空气目标减少到世界卫生组织的空气质量准则:结果:研究结果表明,即使空气污染浓度略有下降,也能产生显著的健康效益。例如,预计将 PM2.5 降低 1 µg/m3 相当于每年将死亡率降低 1%至 2%,心肌梗死病例减少 2%,中风发病率减少 4%,慢性阻塞性肺病减少 2%,肺癌和 2 型糖尿病减少 1%。此外,据估计,这种减少每年可使儿童哮喘病例、妊娠期高血压发病率和早产率分别降低 3%、3% 和 2%: 结论:研究结果表明,即使空气质量稍有改善,也会极大地改善公众健康。
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引用次数: 0
Educational gradients in the quality of mortality data: a nationwide, registry-based study on heart failure listed incorrectly as underlying cause of death in Norway. 死亡率数据质量的教育梯度:一项基于登记簿的全国性研究,针对挪威将心力衰竭错误列为基本死因的情况。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-24 DOI: 10.1177/14034948241296239
Gerhard Sulo, Ann Kristin Knudsen, Carl Baravelli, Christian Lycke Ellingsen, Enxhela Sulo

Aim: In the context of mortality, heart failure (HF) represents an intermediate factor and should not be used to describe underlying cause of death (UCoD). We explored the potential educational gradients in use of HF to describe UCoD using national data spanning more than 30 years from Norway.

Methods: Using a cross-sectional design, we linked data from the Cause of Death Registry and the National Education Database. Logistic regression models were used to analyze the association between highest attained education and the odds of HF being listed as the UCoD: odds ratios (ORs) and corresponding 95% confidence intervals (CIs) are reported.

Results: HF was listed as UCoD in 46,331 (3.7%) of 1,254,249 deaths analyzed. Compared to primary education, secondary and tertiary education were associated with 10% (OR = 0.90, 95% CI: 0.88-0.92) and 17% (OR = 0.83, 95% CI: 0.80-0.86) lower odds of HF incorrectly listed as UCoD, respectively. We observed no significant differences for the association between education and study outcomes between men and women and across place of death categories. However, educational gradients were greater among younger compared to older individuals (pinteraction, = 0.002). Similar educational gradients were observed in the analyses restricted to cardiovascular deaths (OR = 0.93; 95% CI: 0.91-0.94 for secondary vs. primary education, and OR = 0.91; 95% CI: 0.88-0.95 for tertiary vs. primary education).

Conclusions: Education was inversely associated with the use of HF to incorrectly describe UCoD. Addressing the observed educational gradients, would improve the quality of mortality data and allow for less biased descriptions of cause-specific mortality.

目的:在死亡率方面,心力衰竭(HF)是一个中间因素,不应被用来描述潜在死因(UCoD)。我们利用挪威30多年来的全国性数据,探讨了使用心力衰竭来描述潜在死因的潜在教育梯度:我们采用横断面设计,将死因登记和国家教育数据库的数据联系起来。我们使用逻辑回归模型分析了最高学历与HF被列为UCoD的几率之间的关系:报告了几率比(OR)和相应的95%置信区间(CI):在分析的 1,254,249 例死亡病例中,46,331 例(3.7%)被列为合并症。与初等教育相比,中等教育和高等教育分别降低了 10%(OR = 0.90,95% CI:0.88-0.92)和 17%(OR = 0.83,95% CI:0.80-0.86)的 HF 被错误列为 UCoD 的几率。我们观察到,男性和女性之间以及不同死亡地点类别之间的教育程度与研究结果之间没有明显差异。然而,与老年人相比,年轻人的教育梯度更大(pinteraction, = 0.002)。在仅限于心血管死亡的分析中也观察到类似的教育梯度(中等教育与初等教育的OR=0.93;95% CI:0.91-0.94;高等教育与初等教育的OR=0.91;95% CI:0.88-0.95): 结论:教育程度与使用高频错误描述尿道下裂呈反比。解决所观察到的教育梯度问题将提高死亡率数据的质量,并减少对特定病因死亡率描述的偏差。
{"title":"Educational gradients in the quality of mortality data: a nationwide, registry-based study on heart failure listed incorrectly as underlying cause of death in Norway.","authors":"Gerhard Sulo, Ann Kristin Knudsen, Carl Baravelli, Christian Lycke Ellingsen, Enxhela Sulo","doi":"10.1177/14034948241296239","DOIUrl":"https://doi.org/10.1177/14034948241296239","url":null,"abstract":"<p><strong>Aim: </strong>In the context of mortality, heart failure (HF) represents an intermediate factor and should not be used to describe underlying cause of death (UCoD). We explored the potential educational gradients in use of HF to describe UCoD using national data spanning more than 30 years from Norway.</p><p><strong>Methods: </strong>Using a cross-sectional design, we linked data from the Cause of Death Registry and the National Education Database. Logistic regression models were used to analyze the association between highest attained education and the odds of HF being listed as the UCoD: odds ratios (ORs) and corresponding 95% confidence intervals (CIs) are reported.</p><p><strong>Results: </strong>HF was listed as UCoD in 46,331 (3.7%) of 1,254,249 deaths analyzed. Compared to primary education, secondary and tertiary education were associated with 10% (OR = 0.90, 95% CI: 0.88-0.92) and 17% (OR = 0.83, 95% CI: 0.80-0.86) lower odds of HF incorrectly listed as UCoD, respectively. We observed no significant differences for the association between education and study outcomes between men and women and across place of death categories. However, educational gradients were greater among younger compared to older individuals (<i>p</i><sub>interaction</sub>, = 0.002). Similar educational gradients were observed in the analyses restricted to cardiovascular deaths (OR = 0.93; 95% CI: 0.91-0.94 for secondary vs. primary education, and OR = 0.91; 95% CI: 0.88-0.95 for tertiary vs. primary education).</p><p><strong>Conclusions: </strong>\u0000 <b>Education was inversely associated with the use of HF to incorrectly describe UCoD. Addressing the observed educational gradients, would improve the quality of mortality data and allow for less biased descriptions of cause-specific mortality.</b>\u0000 </p>","PeriodicalId":49568,"journal":{"name":"Scandinavian Journal of Public Health","volume":" ","pages":"14034948241296239"},"PeriodicalIF":2.6,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retention of immigrant doctors and nurses in the medical labour markets of the Nordic countries: a scoping review. 北欧国家医疗劳动力市场留住移民医生和护士的情况:范围界定审查。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-19 DOI: 10.1177/14034948241293179
Tania Aase Dræbel, Kristian Larsen, Eik Buhl Petterson, Jane Brandt Sørensen, Flemming Konradsen

Aims: In Nordic countries, the influx of immigrant doctors and nurses has been increasing since 2005, however retention remains a challenge. The aims of this scoping review were to examine the facilitators and barriers to the retention of immigrant doctors and nurses in the Nordic countries in order to inform future studies and interventions.

Method: A scoping review of peer-reviewed studies focusing on the retention of immigrant doctors and nurses in the Nordic countries was conducted using the framework developed by Arksey and O'Malley. In total, 37 studies were included. The analysis entailed both a numerical analysis to provide a descriptive view of frequencies and a thematic analysis utilising Pierre Bourdieu's concepts of field, capital, habitus and doxa.

Results: Facilitators for retaining immigrant doctors and nurses encompassed a sense of belonging, support from management and peers, collegiality, acknowledgement of diverse cultural competencies and the establishment of relevant professional networks. Barriers included unfamiliarity with local healthcare systems, discrimination, inadequate support in entry-level positions, poor psychosocial work environments, and limited professional networks. Few studies focused on the facilitators for retaining immigrant doctors or nurses, few examined the social and economic costs of immigration, and hardly any addressed the processes related to licencing, authorisation and accreditation.

Conclusions: The majority of the included studies framed immigrant doctors and nurses as challenges to management or the medical labour market. The findings indicated a need for a more comprehensive and inclusive approach to health workforce management across the Nordic countries to accommodate the increasingly diverse workforce in terms of international migratory backgrounds.

目的:在北欧国家,移民医生和护士的流入量自 2005 年以来一直在增加,但留住他们仍然是一项挑战。本次范围界定综述旨在研究北欧国家留住移民医生和护士的促进因素和障碍,为今后的研究和干预措施提供参考:方法:采用Arksey和O'Malley制定的框架,对北欧国家移民医生和护士留任问题的同行评审研究进行了范围界定。总共纳入了 37 项研究。分析既包括数字分析,以提供频率的描述性视图,也包括利用皮埃尔-布尔迪厄的领域、资本、习惯和 "哆嗦"(doxa)概念进行的主题分析:结果:留住移民医生和护士的促进因素包括归属感、来自管理层和同行的支持、同事关系、对不同文化能力的认可以及建立相关的专业网络。障碍包括不熟悉当地医疗系统、歧视、初级职位支持不足、社会心理工作环境差以及专业网络有限。很少有研究关注留住移民医生或护士的促进因素,很少有研究探讨移民的社会和经济成本,几乎没有研究涉及与执照、授权和认证相关的程序: 大多数研究都将移民医生和护士视为对管理或医疗劳动力市场的挑战。研究结果表明,北欧国家需要采取更加全面和包容的方法来管理医疗队伍,以适应具有国际移民背景的日益多样化的医疗队伍。
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引用次数: 0
Bridging discourses on health promotion and social sustainability towards healthy community development. 衔接健康促进和社会可持续发展的论述,实现健康的社区发展。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-18 DOI: 10.1177/14034948241290282
Camilla Ihlebæk, Ragnhild Ånestad, Emma C A Nordbø

The aim of this paper is to argue for the need to bridge the discourses of health promotion and social sustainability as an important step toward healthy community development. By building on theories and empirical knowledge from both disciplines, we advocate for the field of health promotion to take a more assertive role within the social sustainability discourse because the theoretical and empirical knowledge from health promotion research is needed. Likewise, we argue that the strong emphasis on social justice and contextual community factors within the social sustainability discourse could contribute to developing the health promotion discourse. Furthermore, we suggest that place-based methods and analyses used in current health promotion research could serve as tools to better integrate knowledge on both physical and social dimensions, thereby enhancing inter-disciplinary collaboration to develop socially sustainable communities.

本文旨在论证弥合健康促进和社会可持续发展论述的必要性,以此作为实现健康社区发展的重要一步。通过借鉴这两个学科的理论和经验知识,我们主张健康促进领域在社会可持续发展论述中发挥更积极的作用,因为我们需要健康促进研究的理论和经验知识。同样,我们认为,在社会可持续发展论述中对社会公正和社区背景因素的大力强调有助于健康促进论述的发展。此外,我们建议,当前健康促进研究中使用的基于地方的方法和分析可以作为工具,更好地整合物理和社会层面的知识,从而加强跨学科合作,发展社会可持续发展社区。
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引用次数: 0
Educational inequalities in mental health expectancy. Analysis based on registry data and survey data from the Danish National Health Survey. 心理健康预期寿命中的教育不平等。根据丹麦全国健康调查的登记数据和调查数据进行分析。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-14 DOI: 10.1177/14034948241296195
Oliver Ryborg Kjeldsen, Michael Davidsen, Henrik Brønnum-Hansen

Objective: Social inequality in life expectancy (LE) and various indicators of health expectancy have received much attention. Mental health expectancy (MHE) has received less attention, although research has shown an increasing prevalence of poor mental health. We aimed to investigate educational differentials in LE in relation to good, moderate, and poor mental health.

Methods: Nationwide registry data on education and mortality were linked and combined with data from the Danish National Health Survey for 2017 and 2021 on mental health and education. The sample group consisted of data on Danes aged 30 and over. MHE was estimated by Sullivan's method.

Results: From 2017 to 2021, a general decline in the MHE of Danes was observed. Furthermore, the educational inequality in MHE remained substantial between genders, and was larger than the inequality in LE. Changes in MHE differed across educational groups. For Danes with short education, good MHE tended to increase for men, while the increase was statistically significant among women.

Conclusions: MHE is associated with educational attainment. Despite the observed changes in educational differential, substantial inequality persists, raising important questions about the underlying causes of social disparity in MHE.

目的:预期寿命(LE)和各种健康预期指标方面的社会不平等现象已受到广泛关注。心理健康预期寿命(MHE)受到的关注较少,尽管研究表明心理健康状况不佳的情况越来越普遍。我们的目的是调查与良好、中等和不良心理健康有关的教育程度差异:将全国范围内有关教育和死亡率的登记数据与 2017 年和 2021 年丹麦全国健康调查中有关心理健康和教育的数据进行链接和合并。样本组包括 30 岁及以上丹麦人的数据。结果显示,从 2017 年到 2021 年,丹麦人的精神健康和教育程度普遍下降:从 2017 年到 2021 年,丹麦人的 MHE 普遍下降。此外,MHE 在两性之间的教育不平等仍然很大,并且大于 LE 的不平等。不同教育群体的 MHE 变化各不相同。对于受教育时间较短的丹麦人来说,男性的良好 MHE 有增加的趋势,而女性的增加在统计上是显著的: 结论:MHE 与教育程度有关。尽管在教育差异方面观察到了变化,但严重的不平等依然存在,这就提出了关于 MHE 社会差异的根本原因的重要问题。
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引用次数: 0
Perceived social support and symptoms of depression and anxiety in emerging adulthood: A Swedish prospective cohort study. 感知到的社会支持与成年后的抑郁和焦虑症状:瑞典前瞻性队列研究。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-06 DOI: 10.1177/14034948241290927
Sara Brolin Låftman, Andreas Lundin, Viveca Östberg

Aims: The transition from adolescence to young adulthood, often referred to as 'emerging adulthood', is a challenging period in life, and mental health problems are common. Although a large number of studies have shown that social support is linked with fewer mental health problems, few longitudinal studies have examined these associations during this life phase. The aim of the current study was to examine the associations between perceived social support from different sources - family, friends and significant other - at age 17-18 and symptoms of depression and anxiety at age 20-21.

Methods: Data were obtained from the cohort study Futura01 based on a Swedish national sample of adolescents attending grade 9 in 2016/2017. We used survey information from 2019 (age 17-18) and 2022 (age 20-21) and linked registry information (N=2722). Symptoms of depression and anxiety were measured by the Patient Health Questionnaire-4 (PHQ-4) at age 20-21. Perceived social support was measured by the Multidimensional Scale of Perceived Social Support (MSPSS) at age 17-18. Control variables included sociodemographic characteristics and indicators of mental health problems at age 17-18. Binary logistic regressions were performed.

Results: When mutually adjusting for all sources of perceived social support, family support at age 17-18 had inverse associations with symptoms of both depression and anxiety at age 20-21. Perceived support from friends was associated with subsequent symptoms of anxiety only.

Conclusions: Perceived social support can be a protective factor against mental health problems in emerging adulthood. The family serves a particularly important source of social support.

目的:从青春期向青年期的过渡通常被称为 "新成人期",这是人生中一个充满挑战的时期,心理健康问题也很常见。尽管大量研究表明,社会支持与较少的心理健康问题有关,但很少有纵向研究对这一人生阶段的这些关联进行考察。本研究旨在探讨 17-18 岁时从家庭、朋友和重要他人等不同来源感知到的社会支持与 20-21 岁时抑郁和焦虑症状之间的关系:数据来自队列研究Futura01,该研究基于2016/2017学年9年级的瑞典全国青少年样本。我们使用了2019年(17-18岁)和2022年(20-21岁)的调查信息以及相关联的登记信息(N=2722)。抑郁和焦虑症状通过 20-21 岁患者健康问卷-4(PHQ-4)进行测量。感知到的社会支持通过 17-18 岁时的感知到的社会支持多维量表(MSPSS)进行测量。控制变量包括 17-18 岁时的社会人口特征和心理健康问题指标。对结果进行了二元逻辑回归:结果:在对所有感知到的社会支持来源进行相互调整后,17-18 岁时的家庭支持与 20-21 岁时的抑郁和焦虑症状呈负相关。结论:感知到的朋友支持仅与随后的焦虑症状有关:结论:感知到的社会支持可以成为预防成年期心理健康问题的保护因素。家庭是一个特别重要的社会支持来源。
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引用次数: 0
Is duration of residence a proxy for acculturation? The case of health risk behaviors among international immigrants. 居住时间是文化适应的替代物吗?以国际移民的健康风险行为为例。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-01 Epub Date: 2023-09-18 DOI: 10.1177/14034948231199534
Sol P Juárez, Helena Honkaniemi, Nina-Katri Gustafsson, Lisa Berg

Aims: Among international immigrants, health changes by duration of residence are commonly interpreted as an expression of acculturation to the receiving country context. This study compares changes in immigrants' health risk behaviors by duration of residence to changes by acculturation levels, in order to assess whether duration of residence can be regarded as a proxy for acculturation.

Methods: Using data from a previous systematic review, we identified 17 quantitative studies examining changes in alcohol, tobacco and drug use, physical inactivity, and diet by both duration of residence and acculturation level in the same population. We compared the directionality and consistency of these associations through tabulation and vote counting.

Results: The majority of studies reported no or inconsistent changes in health risk behaviors by duration of residence versus by acculturation, including with opposite directionality. Four studies reported significant estimates with consistent directionality, while five reported consistent, non-significant estimates.

Conclusions: Our findings suggest that duration of residence should not be used as a proxy for acculturation when studying health risk behaviors among immigrants. Researchers should consider additional time-dependent factors to explain behavioral changes by duration of residence.

目的:在国际移民中,居住时间长短对健康的影响通常被解释为对接受国文化适应的一种表现。本研究比较了移民的健康风险行为随居住时间的变化和文化适应水平的变化,以评估居住时间是否可被视为文化适应的替代指标:我们利用先前系统性综述中的数据,确定了 17 项定量研究,这些研究根据同一人群的居住时间长短和文化适应程度,对酗酒、吸烟、吸毒、缺乏运动和饮食等方面的变化进行了研究。我们通过制表和计票比较了这些关联的方向性和一致性:大多数研究报告称,居住时间与文化程度对健康风险行为的影响没有变化或变化不一致,包括方向相反。四项研究报告了具有一致方向性的显著估计值,五项研究报告了一致但不显著的估计值:我们的研究结果表明,在研究移民的健康风险行为时,不应将居住时间长短作为文化适应程度的替代指标。研究人员应考虑其他与时间相关的因素,以解释居住时间的行为变化。
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Scandinavian Journal of Public Health
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