Pub Date : 2024-11-01Epub Date: 2024-03-20DOI: 10.1016/j.jtcvs.2024.03.021
Igor E Konstantinov, Tyson A Fricke
{"title":"Commentary: Truncal valve repair: Reduce the root, preserve the cusps.","authors":"Igor E Konstantinov, Tyson A Fricke","doi":"10.1016/j.jtcvs.2024.03.021","DOIUrl":"10.1016/j.jtcvs.2024.03.021","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140190367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-07-03DOI: 10.1016/j.jtcvs.2024.05.027
Rawan M Zeineddine, Juan M Farina, Dawn E Jaroszewski
{"title":"Reply: Experience is the true dictum of complications in pectus excavatum surgery, not Haller index.","authors":"Rawan M Zeineddine, Juan M Farina, Dawn E Jaroszewski","doi":"10.1016/j.jtcvs.2024.05.027","DOIUrl":"10.1016/j.jtcvs.2024.05.027","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2023-11-21DOI: 10.1016/j.jtcvs.2023.11.014
Ahmed A Abdelrehim, Joseph A Dearani, Kimberly A Holst, William R Miranda, Heidi M Connolly, Austin L Todd, Luke J Burchill, Hartzell V Schaff, Alberto Pochettino, Elizabeth H Stephens
Objective: Patients with congenital heart disease (CHD) increasingly live into adulthood, often requiring cardiac reoperation. We aimed to assess the outcomes of adults with CHD (ACHD) undergoing repeat sternotomy at our institution.
Methods: Review of our institution's cardiac surgery database identified 1960 ACHD patients undergoing repeat median sternotomy from 1993 to 2023. The primary outcome was early mortality, and the secondary outcome was a composite end point of mortality and significant morbidity. Univariable and multivariable logistic regression models were used to determine factors independently associated with outcomes.
Results: Of the 1960 ACHDs patient undergoing repeat sternotomy, 1183 (60.3%) underwent a second, third (n = 506, 25.8%), fourth (n = 168, 8.5%), fifth (n = 70, 3.5%), and sixth sternotomy or greater (n = 33, 1.6%). CHD diagnoses were minor complexity (n = 145, 7.4%), moderate complexity (n = 1380, 70.4%), and major complexity (n = 435, 22.1%). Distribution of procedures included valve (n = 549, 28%), congenital (n = 625, 32%), aortic (n = 104, 5.3%), and major procedural combinations (n = 682, 34.7%). Overall early mortality was 3.1%. Factors independently associated with early mortality were older age at surgery, CHD of major complexity, preoperative renal failure, preoperative ejection fraction, urgent operation, and postoperative blood transfusion. In addition, sternotomy number and bypass time were independently associated with the composite outcome.
Conclusions: Despite the increase in early mortality with sternotomy number, sternotomy number was not independently associated with early mortality but with increased morbidity. Improvement strategies should target factors leading to urgent operations, early referral, along with operative efficiency including bypass time and blood conservation.
{"title":"Risk factors and early outcomes of repeat sternotomy in 1960 adults with congenital heart disease: A 30-year, single-center study.","authors":"Ahmed A Abdelrehim, Joseph A Dearani, Kimberly A Holst, William R Miranda, Heidi M Connolly, Austin L Todd, Luke J Burchill, Hartzell V Schaff, Alberto Pochettino, Elizabeth H Stephens","doi":"10.1016/j.jtcvs.2023.11.014","DOIUrl":"10.1016/j.jtcvs.2023.11.014","url":null,"abstract":"<p><strong>Objective: </strong>Patients with congenital heart disease (CHD) increasingly live into adulthood, often requiring cardiac reoperation. We aimed to assess the outcomes of adults with CHD (ACHD) undergoing repeat sternotomy at our institution.</p><p><strong>Methods: </strong>Review of our institution's cardiac surgery database identified 1960 ACHD patients undergoing repeat median sternotomy from 1993 to 2023. The primary outcome was early mortality, and the secondary outcome was a composite end point of mortality and significant morbidity. Univariable and multivariable logistic regression models were used to determine factors independently associated with outcomes.</p><p><strong>Results: </strong>Of the 1960 ACHDs patient undergoing repeat sternotomy, 1183 (60.3%) underwent a second, third (n = 506, 25.8%), fourth (n = 168, 8.5%), fifth (n = 70, 3.5%), and sixth sternotomy or greater (n = 33, 1.6%). CHD diagnoses were minor complexity (n = 145, 7.4%), moderate complexity (n = 1380, 70.4%), and major complexity (n = 435, 22.1%). Distribution of procedures included valve (n = 549, 28%), congenital (n = 625, 32%), aortic (n = 104, 5.3%), and major procedural combinations (n = 682, 34.7%). Overall early mortality was 3.1%. Factors independently associated with early mortality were older age at surgery, CHD of major complexity, preoperative renal failure, preoperative ejection fraction, urgent operation, and postoperative blood transfusion. In addition, sternotomy number and bypass time were independently associated with the composite outcome.</p><p><strong>Conclusions: </strong>Despite the increase in early mortality with sternotomy number, sternotomy number was not independently associated with early mortality but with increased morbidity. Improvement strategies should target factors leading to urgent operations, early referral, along with operative efficiency including bypass time and blood conservation.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-01-18DOI: 10.1016/j.jtcvs.2024.01.017
Travis K Martin, Aaron Dinerman, Sumedha Sudhaman, Griffin Budde, Charuta C Palsuledesai, Michael Krainock, Minetta C Liu, Emy Smith, Leonidas Tapias, Eitan Podgaetz, Gary Schwartz
Objective: The study objective was to evaluate the impact of monitoring circulating tumor DNA on the detection and management of recurrence in patients with resected early-stage non-small cell lung cancer.
Methods: Between October 2021 and March 2023, postoperative circulating tumor DNA was monitored in patients with non-small cell lung cancer (N = 108). Longitudinal blood samples (n = 378 samples) were collected for prospective circulating tumor DNA analysis at 3-month intervals after curative-intent resection. A tumor-informed assay was used for the detection and quantification of circulating tumor DNA. The primary outcome measure was a circulating tumor DNA-positive result. The secondary outcome measure was changes in practice after a circulating tumor DNA-positive result.
Results: The mean age of the patients in this cohort was 68.1 years. Of the 108 patients, 12 (11.1%) were circulating tumor DNA positive at least at 1 timepoint postsurgery, of whom 8 (66.7%) had a clinically evident recurrence and the remaining 4 had limited clinical follow-up. Of the 10 patients with recurrent disease, 8 demonstrated circulating tumor DNA positivity and the remaining 2 patients had brain-only metastases. Postoperative clinical care was altered in 100% (12/12) of circulating tumor DNA-positive patients, with 58.3% (7/12) receiving an early computed tomography scan and 100% (12/12) receiving an early positron emission tomography computed tomography scan as part of their surveillance strategy. Among the patients who received an early positron emission tomography scan, 66.6% (8/12) were positive for malignant features.
Conclusions: Routine monitoring of tumor-informed circulating tumor DNA after curative intent therapy improved patient risk stratification and prognostication.
目的评估监测循环肿瘤DNA(ctDNA)对早期非小细胞肺癌(NSCLC)切除患者复发检测和管理的影响:方法:2021年10月至2023年3月期间,对NSCLC患者(108人)的术后ctDNA进行监测。采集纵向血液样本(样本数=378),在治愈性切除术后每隔3个月进行前瞻性ctDNA分析。ctDNA的检测和定量采用肿瘤信息分析法。主要结果指标是ctDNA阳性结果。次要结果指标是出现ctDNA阳性结果后的实践变化:本组患者的平均年龄为 68.1 岁。在108名患者中,有12名患者(11.1%)在术后至少一个时间点上ctDNA呈阳性,其中8名患者(66.7%)有明显的临床复发,其余4名患者的临床随访有限。在 10 名复发患者中,8 名患者的ctDNA呈阳性,2 名患者仅有脑转移。在ctDNA阳性患者中,100%(12/12)的患者术后临床护理发生了改变,其中58.3%(7/12)的患者接受了早期CT扫描,100%(12/12)的患者接受了早期PET-CT扫描,作为其监测策略的一部分。在接受早期 PET 扫描的患者中,66.6%(8/12)的患者恶性特征呈阳性:结论:治愈性治疗后对肿瘤信息ctDNA的常规监测可改善患者的风险分层和预后。
{"title":"Early real-world experience monitoring circulating tumor DNA in resected early-stage non-small cell lung cancer.","authors":"Travis K Martin, Aaron Dinerman, Sumedha Sudhaman, Griffin Budde, Charuta C Palsuledesai, Michael Krainock, Minetta C Liu, Emy Smith, Leonidas Tapias, Eitan Podgaetz, Gary Schwartz","doi":"10.1016/j.jtcvs.2024.01.017","DOIUrl":"10.1016/j.jtcvs.2024.01.017","url":null,"abstract":"<p><strong>Objective: </strong>The study objective was to evaluate the impact of monitoring circulating tumor DNA on the detection and management of recurrence in patients with resected early-stage non-small cell lung cancer.</p><p><strong>Methods: </strong>Between October 2021 and March 2023, postoperative circulating tumor DNA was monitored in patients with non-small cell lung cancer (N = 108). Longitudinal blood samples (n = 378 samples) were collected for prospective circulating tumor DNA analysis at 3-month intervals after curative-intent resection. A tumor-informed assay was used for the detection and quantification of circulating tumor DNA. The primary outcome measure was a circulating tumor DNA-positive result. The secondary outcome measure was changes in practice after a circulating tumor DNA-positive result.</p><p><strong>Results: </strong>The mean age of the patients in this cohort was 68.1 years. Of the 108 patients, 12 (11.1%) were circulating tumor DNA positive at least at 1 timepoint postsurgery, of whom 8 (66.7%) had a clinically evident recurrence and the remaining 4 had limited clinical follow-up. Of the 10 patients with recurrent disease, 8 demonstrated circulating tumor DNA positivity and the remaining 2 patients had brain-only metastases. Postoperative clinical care was altered in 100% (12/12) of circulating tumor DNA-positive patients, with 58.3% (7/12) receiving an early computed tomography scan and 100% (12/12) receiving an early positron emission tomography computed tomography scan as part of their surveillance strategy. Among the patients who received an early positron emission tomography scan, 66.6% (8/12) were positive for malignant features.</p><p><strong>Conclusions: </strong>Routine monitoring of tumor-informed circulating tumor DNA after curative intent therapy improved patient risk stratification and prognostication.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139512890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-03-04DOI: 10.1016/j.jtcvs.2024.02.020
Annalisa Bernabei, Andrew J Toth, A Marc Gillinov, Eugene H Blackstone, Michael B Komarovsky, Jacky H K Chen, Peter Chin, James C Witten, Daniel J P Burns, Patrick Collier, Rohit Moudgil, Eric E Roselli
{"title":"Surgical resection of benign primary cardiac tumors: A 6-decade evaluation of survival and recurrence.","authors":"Annalisa Bernabei, Andrew J Toth, A Marc Gillinov, Eugene H Blackstone, Michael B Komarovsky, Jacky H K Chen, Peter Chin, James C Witten, Daniel J P Burns, Patrick Collier, Rohit Moudgil, Eric E Roselli","doi":"10.1016/j.jtcvs.2024.02.020","DOIUrl":"10.1016/j.jtcvs.2024.02.020","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-06-15DOI: 10.1016/j.jtcvs.2024.05.015
Bobiet Aurélien, Géraldine Allain, Pierre Corbi, Jamil Hajj-Chahine, Christophe Jayle
{"title":"Thrombus within a stent graft.","authors":"Bobiet Aurélien, Géraldine Allain, Pierre Corbi, Jamil Hajj-Chahine, Christophe Jayle","doi":"10.1016/j.jtcvs.2024.05.015","DOIUrl":"10.1016/j.jtcvs.2024.05.015","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141328033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-08-19DOI: 10.1016/j.jtcvs.2024.07.051
{"title":"Discussion to: New perspectives on tracheal resection for COVID-19-related stenosis: A propensity score matching analysis.","authors":"","doi":"10.1016/j.jtcvs.2024.07.051","DOIUrl":"10.1016/j.jtcvs.2024.07.051","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2023-11-28DOI: 10.1016/j.jtcvs.2023.11.013
{"title":"Discussion to: Heterogeneous treatment effects of coronary artery bypass grafting in ischemic cardiomyopathy: A machine-learning causal forest analysis.","authors":"","doi":"10.1016/j.jtcvs.2023.11.013","DOIUrl":"10.1016/j.jtcvs.2023.11.013","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-01-22DOI: 10.1016/j.jtcvs.2024.01.024
Sameer K Singh, Ismail Bouhout, Stephanie Nguyen, Alice Vinogradsky, Anna Lampe, Morgan Moroi, Michael Salna, Hiroo Takayama, Emile Bacha, Andrew B Goldstone
Objective: Preoperative aortic insufficiency (AI) is associated with inferior autograft durability after the Ross procedure. However, many patients with aortic stenosis (AS) undergo balloon aortic valvuloplasty (BAV) early and present with longstanding AI before Ross. We studied how BAV and subsequent valvular pathology impacts autograft durability.
Methods: Patients undergoing the Ross operation from 1993 to 2020 were identified. Those who underwent BAV before Ross were compared with patients who did not undergo BAV and underwent Ross for predominant AI (AI group) or AS (AS group). Those who underwent previous open surgical aortic valve intervention were excluded. Primary outcome of interest was autograft failure, defined as a composite of autograft reintervention or severe insufficiency.
Results: A total of 198 patients were included. Seventy-nine (39.9%) underwent BAV and subsequently underwent the Ross for predominant AI (45.6%) or AS (54.4%). Of patients who did not undergo BAV, 66 (33.3%) presented with predominant AI and 53 (26.8%) with AS. Freedom from autograft failure at 15 years was 90%, 92%, and 62% in BAV, AS, and AI groups, respectively. The AI group was at significantly increased risk of long-term autograft failure (hazard ratio, 5.6; P = .01), whereas the AS and BAV groups had similar, low risk (hazard ratio, 1.1; P = .91). Autograft durability was similar among patients who received BAV and presented with AS or AI before the Ross (P = .84).
Conclusions: BAV before the Ross procedure is common in patients with AS. These patients have excellent long-term autograft durability regardless of preoperative valvular pathology and should strongly be considered for the Ross operation.
目的:术前主动脉瓣关闭不全(AI)与罗斯手术后自体移植的耐久性较差有关。然而,许多主动脉瓣狭窄(AS)患者很早就接受了球囊主动脉瓣成形术(BAV),并在 Ross 术前就出现了长期的 AI。我们研究了 BAV 和随后的瓣膜病变对自体移植耐久性的影响:我们对 1993-2020 年间接受罗斯手术的患者进行了鉴定。方法:我们对 1993-2020 年间接受 Ross 手术的患者进行了鉴定,将 Ross 手术前接受 BAV 的患者与未接受 BAV 但因主要 AI(AI 组)或 AS(AS 组)接受 Ross 手术的患者进行了比较。之前接受过开放手术房室介入治疗的患者被排除在外。主要研究结果为自体移植失败,即自体移植再介入或严重功能不全:结果:共纳入 198 名患者。79名患者(39.9%)接受了BAV手术,随后因AI(45.6%)或AS(54.4%)为主接受了Ross手术。在未接受 BAV 手术的患者中,66 人(33.3%)为主要 AI,53 人(26.8%)为 AS。BAV组、AS组和AI组15年后自体移植失败的发生率分别为90%、92%和62%。AI组发生长期自体移植失败的风险明显增加(HR 5.6,P=0.01),而AS组和BAV组的风险相似且较低(HR 1.1,P=0.91)。Ross术前出现AS或AI的BAV患者的自体移植耐久性相似(P=0.84):结论:Ross术前BAV在AS患者中很常见。结论:Ross手术前BAV在AS患者中很常见,无论术前瓣膜病变如何,这些患者都有很好的长期自体移植耐久性,应积极考虑进行Ross手术。
{"title":"Aortic insufficiency following balloon aortic valvuloplasty does not impact long-term autograft durability after the Ross procedure.","authors":"Sameer K Singh, Ismail Bouhout, Stephanie Nguyen, Alice Vinogradsky, Anna Lampe, Morgan Moroi, Michael Salna, Hiroo Takayama, Emile Bacha, Andrew B Goldstone","doi":"10.1016/j.jtcvs.2024.01.024","DOIUrl":"10.1016/j.jtcvs.2024.01.024","url":null,"abstract":"<p><strong>Objective: </strong>Preoperative aortic insufficiency (AI) is associated with inferior autograft durability after the Ross procedure. However, many patients with aortic stenosis (AS) undergo balloon aortic valvuloplasty (BAV) early and present with longstanding AI before Ross. We studied how BAV and subsequent valvular pathology impacts autograft durability.</p><p><strong>Methods: </strong>Patients undergoing the Ross operation from 1993 to 2020 were identified. Those who underwent BAV before Ross were compared with patients who did not undergo BAV and underwent Ross for predominant AI (AI group) or AS (AS group). Those who underwent previous open surgical aortic valve intervention were excluded. Primary outcome of interest was autograft failure, defined as a composite of autograft reintervention or severe insufficiency.</p><p><strong>Results: </strong>A total of 198 patients were included. Seventy-nine (39.9%) underwent BAV and subsequently underwent the Ross for predominant AI (45.6%) or AS (54.4%). Of patients who did not undergo BAV, 66 (33.3%) presented with predominant AI and 53 (26.8%) with AS. Freedom from autograft failure at 15 years was 90%, 92%, and 62% in BAV, AS, and AI groups, respectively. The AI group was at significantly increased risk of long-term autograft failure (hazard ratio, 5.6; P = .01), whereas the AS and BAV groups had similar, low risk (hazard ratio, 1.1; P = .91). Autograft durability was similar among patients who received BAV and presented with AS or AI before the Ross (P = .84).</p><p><strong>Conclusions: </strong>BAV before the Ross procedure is common in patients with AS. These patients have excellent long-term autograft durability regardless of preoperative valvular pathology and should strongly be considered for the Ross operation.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11260901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139547604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-03-22DOI: 10.1016/j.jtcvs.2024.03.022
Uma M Sachdeva
{"title":"Commentary: Circulating tumor DNA in resectable non-small cell lung cancer: Emerging canary in the coal mine.","authors":"Uma M Sachdeva","doi":"10.1016/j.jtcvs.2024.03.022","DOIUrl":"10.1016/j.jtcvs.2024.03.022","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140208147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}