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A Study on the Design of Music Curriculum-Based Ecological Environment Convergence Education Program for Elementary School Learners 基于音乐课程的小学生生态环境融合教育课程设计研究
Pub Date : 2024-03-22 DOI: 10.32388/rjb174
Bolim Lee
This study is to devise a convergence education program with the ecological environment based on the music of elementary school learners. Various agendas surrounding the environment, such as carbon neutrality, climate crisis, and ecological environment conservation, are also being discussed with enthusiasm in the education world. From this point of view, this study is expected to be an education that can be practiced in their lives in the future by properly establishing elementary school learners' values for nature and the environment as well as music subject content in the music education field. To this end, this study developed a new music education program that can further implement environmental education based on two previous studies on music-based convergence education through literature research methods. Through this, conclusions corresponding to four implications were drawn, and it can be said that the review that environmental education can be practiced in a fusion manner within music education has been conducted to some extent.
本研究旨在根据小学生的音乐特点,设计与生态环境相融合的教育方案。围绕环境的各种议程,如碳中和、气候危机、生态环境保护等,也正在教育界热烈讨论。从这一角度出发,本研究通过在音乐教育领域正确树立小学生对自然和环境以及音乐学科内容的价值观,期望能成为他们今后生活中可以实践的教育。为此,本研究通过文献研究法,在前两项基于音乐的融合教育研究的基础上,开发了一种新的音乐教育课程,可以进一步实施环境教育。通过这些研究,得出了与四个影响相对应的结论,可以说在一定程度上回顾了环境教育可以在音乐教育中以融合的方式进行。
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引用次数: 0
Willingness-To-Pay for Health Insurance: Protocol for a Comparative Study Between Formal and Informal Health-Workers 医疗保险的支付意愿:正规和非正规医疗工作者比较研究的规程
Pub Date : 2024-03-21 DOI: 10.32388/tzk4c7.3
Md Fuad Al Fidah
INTRODUCTIONPeople in low- to middle-income countries (LMICs), such as Bangladesh, have less access to healthcare than those in wealthier nations with less than 1% of the population having access to social health protection, which is mostly limited to those who work in the formal sector (14.9% of all jobs). This comparative study aims to use the contingent valuation method (CVM) to determine the factors affection and compare the mean willingness-to-pay (WTP) for community-based health insurance (CBHI) between formal and informal health workers.METHODS AND ANALYSISThis comparative study will be conducted among 250 doctors who will be selected by a convenience sampling technique from various formal and informal workstations in Dhaka City. Of the 250 participants, 125 will be from each group. To collect data, a semi-structured questionnaire will be used via face-to-face interviews. Data will be processed and analyzed using R (v4.3.0) and RStudio (v2023.03.1). WTP for CBHI will be estimated using the “DCchoice” package. The primary outcome is to estimate the proportion and mean WTP across the groups and compare it using double bound dichotomous choice (DBDC) method. Secondary outcomes include identifying the socio-demographic, job-related and healthcare seeking-related factors that influence the WTP.ETHICS AND DISSEMINATIONEthics approval has been obtained from Institutional Review Board (IRB) of the National Institute of Preventive and Social Medicine (NIPSOM). Informed consent will be taken from each participant before data collection. The results of the study will be published in scientific, peer-reviewed journals.STRENGTHS AND LIMITATIONS OF THIS STUDY– The contingent valuation method is a well-established method of eliciting WTP for health insurance.– The current study will be among the first of its nature as it will focus on formal and informal healthcare workers.– Starting point bias may affect the result as this type of bias comes with the Double bounded dichotomous choice (DBDC) method used in this study.
导言孟加拉国等中低收入国家(LMICs)的人民与富裕国家的人民相比,享受医疗保健的机会较少,只有不到 1%的人口能够享受社会健康保障,而这种保障主要限于那些在正规部门工作的人(占所有工作的 14.9%)。本比较研究旨在使用或然估价法(CVM)确定影响因素,并比较正规和非正规医务工作者对社区医疗保险(CBHI)的平均支付意愿(WTP)。在 250 名参与者中,每组 125 人。为了收集数据,将通过面对面访谈的方式使用半结构化问卷。数据将使用 R (v4.3.0) 和 RStudio (v2023.03.1) 进行处理和分析。CBHI 的 WTP 将使用 "DCchoice "软件包进行估算。主要结果是估算各组的 WTP 比例和平均值,并使用双界二分选择法(DBDC)进行比较。次要结果包括确定影响 WTP 的社会人口学因素、工作相关因素和医疗保健寻求相关因素。在收集数据之前,将征得每位参与者的知情同意。本研究的优点和局限性--或然估价法是一种行之有效的医疗保险 WTP 激发方法。--本研究将关注正规和非正规医疗保健工作者,因此是首次开展此类研究。
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引用次数: 0
The Win-Win-Win Papakonstantinidis Model and the Economic MRS: Some Lessons From Linear B Papakonstantinidis 双赢模型和经济 MRS:线性 B 的一些启示
Pub Date : 2024-03-21 DOI: 10.32388/7zis77
Leonidas Papakonstantinidis
The suggested "win-win-win papakonstantinidis model" (coming from Nash1 win-win extended approach) tries to find ways for the three-pole bargaining conceptual equilibrium, under conditions, thus maximizing expected utilities for all the involved parties AND the Community in local decision-making by applying a combination of Descriptive Behavior (DB), Rational Choice, Instrumental Rationality and the Applied Behavioral Analysis (ABA) methodologies, then an updating community's behavioral state is expected.In the opposite, the Marginal Rate of Substitution - which is analyzed from the view of Political Economy- leads our thoughts into the pure individualism and the need to interpret all the transactions we make and the corresponding decisions through the maximization of our individual satisfactionBy this definition the win-win-win papakonstantinidis model2 helps the scientific thought so to understand the "socially acceptable substitution" thus deriving profit from providing the community with the necessary “emotional intelligence” among the people of a self-organizing community, drawing stimuli from distributions made in the Greek area 1450 years BC.
所建议的 "三赢帕帕康斯坦丁尼蒂斯模型"(源自纳什1 的双赢扩展方法)试图找到三极讨价还价概念均衡的方法,在此条件下,通过综合运用描述性行为(DB)、理性选择、工具理性和应用行为分析(ABA)等方法,使所有参与方和社区在地方决策中的预期效用最大化,从而有望更新社区的行为状态。与此相反,边际替代率--从政治经济学的角度进行分析--将我们的思想引向纯粹的个人主义,需要通过个人满意度的最大化来解释我们所做的所有交易和相应的决定。根据这一定义,三赢帕帕康斯坦丁尼蒂斯模型2 帮助科学思想理解 "社会可接受的替代",从而从为社区提供必要的 "情商 "中获利,自组织社区的人们从公元前 1450 年希腊地区的分配中汲取灵感。
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引用次数: 0
Review of: "Probabilistic Assessment of the Heavy Metal Pollution in Debrecen’s Topsoil" 评论"德布勒森表土重金属污染的概率评估"
Pub Date : 2024-03-21 DOI: 10.32388/5q2sdq
Liu Jutao
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引用次数: 0
Positive Thinking and Laughter Therapy 积极思考和笑声疗法
Pub Date : 2024-03-21 DOI: 10.32388/4yjtt3
Nour Rammal, Elio Mubarak, Hadi Ftouni, Rayane Tahesh, Zinnia Shweiry
«This manuscript investigates the efficacy of laughter therapy and positive thinking as complementary treatments for individuals with chronic diseases in Lebanon, amidst an ongoing economic crisis. Chronic diseases are a significant public health issue globally and in Lebanon, where the economic situation exacerbates healthcare challenges. Traditional biomedical treatments, while essential, are becoming increasingly costly, highlighting the need for cost-effective, alternative therapeutic approaches. Through qualitative methodology, including semi-structured interviews with a medical doctor and a clinical psychologist, and a case study of a Lebanese woman with a ruptured disk, this study explores the mental, physical, and economic impacts of laughter therapy and positive thinking. Findings suggest these therapies can enhance psychological well-being, manage symptoms, and potentially reduce healthcare costs, offering a holistic approach to chronic disease management. The study emphasizes the importance of integrating these complementary therapies into standard medical care, proposing a promising avenue for improving the lives of individuals with chronic diseases in Lebanon and beyond.
"本手稿研究了在黎巴嫩持续的经济危机中,笑声疗法和积极思考作为慢性病患者的辅助治疗方法的疗效。慢性疾病是全球和黎巴嫩的一个重大公共卫生问题,黎巴嫩的经济状况加剧了医疗保健方面的挑战。传统的生物医学治疗虽然必不可少,但成本却越来越高,这凸显了对具有成本效益的替代治疗方法的需求。本研究通过定性方法,包括对一名医生和一名临床心理学家进行半结构式访谈,以及对一名椎间盘破裂的黎巴嫩妇女进行案例研究,探讨了笑声疗法和积极思考对心理、身体和经济的影响。研究结果表明,这些疗法可以提高心理健康水平,控制症状,并有可能降低医疗成本,为慢性病管理提供了一种全面的方法。这项研究强调了将这些辅助疗法纳入标准医疗保健的重要性,为改善黎巴嫩及其他地区慢性病患者的生活提出了一条大有可为的途径。
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引用次数: 0
A Novel One-Pot Three-Component Approach to Orthoaminocarbonitrile Tetrahydronaphthalenes Using Triethylamine (Et_3N) as a Highly Efficient and Homogeneous Catalyst Under Mild Conditions and Investigating Its Anti-cancer Properties Through Molecular Docking Studies and Calculations 在温和条件下以三乙胺 (Et_3N) 为高效均相催化剂一锅三组分制备正交氨基甲腈四氢萘的新方法,并通过分子对接研究和计算探讨其抗癌特性
Pub Date : 2024-03-20 DOI: 10.32388/urq6fq
Abdulhamid Dehghani, Yousef Delshad, Moslem Ahmadpour, Milad Ghezelsofloo
An efficient and environmentally friendly method for the one-pot synthesis of ortho-aminocarbonitrile tetrahydronaphthalenes has been developed in the presence of triethylamine (Et3N) as a homogeneous catalyst. The multicomponent reactions of benzaldehydes, cyclohexanone and malononitrile were carried out under mild conditions to obtain some ortho-aminocarbonitrile tetrahydronaphthalene derivatives. A broad range of structurally diverse benzaldehydes were applied successfully, and corresponding products (4A-L) were obtained in good to excellent yields (87-98%) in very short times (10-25 minutes). The present approach provides several advantages including simple workup, high yields, very mild reaction conditions, short reaction times, little catalyst loading and not requiring specialized equipment. Furthermore, with the help of computational chemistry and drug design methods, the anti-cancer properties of these compounds were studied and investigated. All the synthesized compounds bind to an agonist at the active site of the 3A8P protein, which leads to the inactivation of this protein and produces beneficial effects during cancer treatment. In synthesized compounds, the ligands establish hydrogen bonds with leucine A:728 residues through nitrogen, which has a very special and vital role in biological sciences and pharmaceutical connections. In this study, it was found that these compounds have the potential to become an oral anti-cancer drug.
在三乙胺(Et3N)作为均相催化剂的条件下,开发出了一种高效、环保的单锅合成邻氨基甲腈四氢萘的方法。在温和的条件下进行了苯甲醛、环己酮和丙二腈的多组分反应,得到了一些邻氨基甲腈四氢萘衍生物。研究人员成功地应用了多种结构不同的苯甲醛,并在很短的时间内(10-25 分钟)获得了相应的产物(4A-L),收率从良好到极佳(87-98%)不等。本方法具有多个优点,包括操作简单、产率高、反应条件非常温和、反应时间短、催化剂负载量少以及无需专用设备。此外,在计算化学和药物设计方法的帮助下,对这些化合物的抗癌特性进行了研究和调查。所有合成的化合物都与 3A8P 蛋白活性位点上的激动剂结合,从而导致该蛋白失活,并在癌症治疗过程中产生有益的效果。在合成的化合物中,配体通过氮与亮氨酸 A:728 残基建立了氢键,这在生物科学和医药联系中具有非常特殊和重要的作用。这项研究发现,这些化合物具有成为口服抗癌药物的潜力。
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引用次数: 0
Synthesis of 1, 2-Disubstituted Benzimidazoles at Ambient Temperature Catalyzed by 1-Methylimidazolium Tetraflouroborate ([Hmim] BF_4) and Investigating Their Anti-ovarian Cancer Properties Through Molecular Docking Studies and Calculations 在 1-甲基咪唑鎓四氟硼酸盐([Hmim] BF_4)催化下常温合成 1, 2-二取代苯并咪唑,并通过分子对接研究和计算探讨其抗卵巢癌特性
Pub Date : 2024-03-20 DOI: 10.32388/r7liup
Abdulhamid Dehghani, Yousef Delshad, Moslem Ahmadpour, Milad Ghezelsofloo
An environmentally benign method for the synthesis of 1, 2-disubstituted benzimidazoles by the reaction of aromatic aldehydes and o-phenylenediamines (OPD) in the presence of 1-methylimidazolium tetraflouroborate ([Hmim] BF4) at ambient temperature under green conditions is described. A broad range of structurally diverse benzaldehydes were applied successfully, and corresponding products were obtained in good to excellent yields in very short times. All products were identified by the melting points, 1H and 13C NMR techniques. Furthermore, with the help of computational chemistry and drug design methods, the anti-ovarian cancer properties of these compounds were studied and investigated. All the synthesized compounds bind to an agonist at the active site of the 6LAD protein, which leads to the inactivation of this protein and produces beneficial effects during ovarian cancer treatment. In this study, it was found that these compounds have the potential to become an oral anti-cancer drug.
本研究介绍了一种在绿色条件下,通过芳香醛和邻苯二胺(OPD)在 1-甲基咪唑四氟硼酸盐([Hmim] BF4)存在下于常温反应合成 1,2-二取代苯并咪唑的环保方法。研究人员成功地应用了多种结构不同的苯甲醛,并在很短的时间内以良好到极佳的收率获得了相应的产物。所有产物都通过熔点、1H 和 13C NMR 技术进行了鉴定。此外,在计算化学和药物设计方法的帮助下,对这些化合物的抗卵巢癌特性进行了研究和调查。所有合成的化合物都与 6LAD 蛋白活性位点的激动剂结合,从而导致该蛋白失活,并在卵巢癌治疗过程中产生有益的效果。这项研究发现,这些化合物具有成为口服抗癌药物的潜力。
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引用次数: 0
Estimates of Atlantic Goliath Grouper (Epinephelus Itajara) Bycatch Mortality in Commercial Fisheries of the Southeastern Us From 2002 to 2022 2002 年至 2022 年美国东南部商业渔业中大西洋歌利亚石斑鱼(Epinephelus Itajara)兼捕死亡率的估计值
Pub Date : 2024-03-19 DOI: 10.32388/rwef3z
Christopher Koenig, Felicia Coleman, James V. Locascio
Atlantic Goliath Grouper _Epinephelus itajara _is experiencing a population decline in the southeastern United States currently due to a combination of factors, including increasingly large and persistent red tides, loss of juvenile habitat, severe cold-weather events, and bycatch, the unintended capture by commercial and recreational fishers. In this paper, we review the extent of bycatch in the southeastern United States from 2002 to 2022 resulting from commercial fishing only based on data from NOAA Fisheries logbooks. We calculated depth-of-capture-related mortality based on known patterns of depth-related barotrauma and assumed that all captures deeper than 30 m that were unvented prior to release died based on observations of other researchers. The overall result is that 75% (14,124 of 18,770) _Epinephelus itajara_ captures died from both barotrauma and from inability of the fish to return to the bottom due to trapped swim bladder gas.
大西洋歌利亚石斑鱼(Epinephelus itajara)目前在美国东南部正经历着种群数量的下降,这是由多种因素共同造成的,包括越来越大和持续的赤潮、幼鱼栖息地的丧失、严寒天气事件和副渔获物(商业和休闲捕鱼者的意外捕获)。在本文中,我们根据来自 NOAA 渔业日志的数据,回顾了 2002 年至 2022 年美国东南部仅由商业捕捞造成的副渔获物范围。我们根据与深度相关的气压创伤的已知模式计算与捕获深度相关的死亡率,并根据其 他研究人员的观察假设所有深度超过 30 米、释放前未通风的捕获物死亡。总的结果是,75%(18770 条中的 14124 条)_Epinephelus itajara_ 捕获物死于气压创伤和鱼鳔气体滞留导致的无法返回海底。
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引用次数: 0
[Case Study] Low-Level Laser and Its Interface With Sleep Dentistry: Clinical Case Report [病例研究] 低强度激光及其与睡眠牙科的结合:临床病例报告
Pub Date : 2024-03-19 DOI: 10.32388/s6f5jd
V. H. Panhóca, Carolina Alvarez, Viviane Brocca de Souza, Simone Aparecida Ferreira, Marcela Sene-Fiorese, V. Bagnato
INTRODUCTION: This study aimed to evaluate and raise the therapeutic hypothesis of the use of low-level laser as a complementary therapy in patients with sleep disorder (SD) in a broad approach involving other pathologies superimposed on this pathology.METHODS: This is a clinical case report of a patient with Parkinson's disease (PD) complaining of sleep disorder. The proposed treatment is the use of photobiomodulation (FB) with intraoral application using an innovative dosimetry. SD was assessed using an adapted analogue scale.RESULTS: In the evaluation performed after the last session, there was an improvement in the sleep disorder compared to the pre-treatment evaluation. However, one month after the end of the treatment, it was observed that the quality of sleep remained practically the same.CONCLUSION: We can conclude that low-potency FB can be a modulator in the production of neurotransmitter substances in a local and systemic way, being a complementary or alternative treatment for patients with sleep disorder (SD).
简介:本研究旨在评估和提出一种治疗假设,即使用低强度激光作为睡眠障碍(SD)患者的一种辅助治疗方法,并广泛涉及叠加在该病症上的其他病症。方法:这是一个临床病例报告,患者患有帕金森病(PD),主诉睡眠障碍。建议的治疗方法是使用创新剂量测量法在口腔内应用光生物调制(FB)。结果:在最后一次治疗后进行的评估中,患者的睡眠障碍与治疗前相比有所改善。结论:我们可以得出结论,低效枸杞多糖可以调节局部和全身神经递质物质的产生,是睡眠障碍(SD)患者的一种补充或替代疗法。
{"title":"[Case Study] Low-Level Laser and Its Interface With Sleep Dentistry: Clinical Case Report","authors":"V. H. Panhóca, Carolina Alvarez, Viviane Brocca de Souza, Simone Aparecida Ferreira, Marcela Sene-Fiorese, V. Bagnato","doi":"10.32388/s6f5jd","DOIUrl":"https://doi.org/10.32388/s6f5jd","url":null,"abstract":"INTRODUCTION: This study aimed to evaluate and raise the therapeutic hypothesis of the use of low-level laser as a complementary therapy in patients with sleep disorder (SD) in a broad approach involving other pathologies superimposed on this pathology.\u0000\u0000METHODS: This is a clinical case report of a patient with Parkinson's disease (PD) complaining of sleep disorder. The proposed treatment is the use of photobiomodulation (FB) with intraoral application using an innovative dosimetry. SD was assessed using an adapted analogue scale.\u0000\u0000RESULTS: In the evaluation performed after the last session, there was an improvement in the sleep disorder compared to the pre-treatment evaluation. However, one month after the end of the treatment, it was observed that the quality of sleep remained practically the same.\u0000\u0000CONCLUSION: We can conclude that low-potency FB can be a modulator in the production of neurotransmitter substances in a local and systemic way, being a complementary or alternative treatment for patients with sleep disorder (SD).\u0000","PeriodicalId":500839,"journal":{"name":"Qeios","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140228843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the Spread of Covid-19 via Atangana-Baleanu Fractional Derivatives 通过阿坦加纳-巴莱阿努分式衍生物分析 Covid-19 的传播情况
Pub Date : 2024-03-19 DOI: 10.32388/d7u6ud
M. A. Zaitri, Naas Adjimi
We study the spread of the epidemic via Atangana-Baleanu Fractional Derivatives. We present the mathematical analysis and formulation of a fractional model for the epidemic. The existence and uniqueness of the solution for the proposed model are proved. The study also investigates the existence of disease-free equilibrium and analyzes its stability properties. To validate the theoretical results, we provide a numerical scheme for the fractional model and present various simulation results. These results can serve as a valuable resource in developing strategies to mitigate the spread of the epidemic.
我们通过阿坦加纳-巴莱阿努分式导数研究了流行病的传播。我们介绍了该流行病分数模型的数学分析和公式。证明了所提模型解的存在性和唯一性。研究还探讨了无疾病平衡的存在性,并分析了其稳定性。为了验证理论结果,我们提供了分数模型的数值方案,并给出了各种模拟结果。这些结果可作为制定战略以缓解流行病传播的宝贵资源。
{"title":"Analysis of the Spread of Covid-19 via Atangana-Baleanu Fractional Derivatives","authors":"M. A. Zaitri, Naas Adjimi","doi":"10.32388/d7u6ud","DOIUrl":"https://doi.org/10.32388/d7u6ud","url":null,"abstract":"We study the spread of the epidemic via Atangana-Baleanu Fractional Derivatives. We present the mathematical analysis and formulation of a fractional model for the epidemic. The existence and uniqueness of the solution for the proposed model are proved. The study also investigates the existence of disease-free equilibrium and analyzes its stability properties. To validate the theoretical results, we provide a numerical scheme for the fractional model and present various simulation results. These results can serve as a valuable resource in developing strategies to mitigate the spread of the epidemic.\u0000","PeriodicalId":500839,"journal":{"name":"Qeios","volume":"132 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140228186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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