Pub Date : 2025-11-12DOI: 10.1016/j.bjps.2025.11.012
Fu Laihua , Xiao Wanyi , Liu Yuanxin , Huang Jingyang , Zhou Yang , Xu Songfeng , Qiu Jin , Zhao Zhigang , Yang Jilong
Background and objective
Although pedicled flaps are widely used in trunk reconstruction, evidence remains limited regarding their efficacy in patients with soft tissue sarcoma (STS) requiring wide resection with skeletal involvement.
Methods
This retrospective cohort study analyzed 42 consecutive patients who underwent pedicled flap reconstruction after trunk sarcoma resection at our institution (2019–2024). Flap types included 30 fasciocutaneous and 12 myocutaneous flaps. Outcomes included flap survival (photographic/Doppler assessment) and complications (Clavien-Dindo). Statistical analysis was performed using the Fisher's exact test and Kaplan-Meier methods (SPSS v26).
Results
The cohort demonstrated favorable outcomes with pedicled flap reconstruction (92.86% primary healing rate). Among skeletal defect cases, reconstructions used soft prostheses (n = 6), rigid prostheses (n = 2), or mesh reinforcement (n = 2). During the 11–59 month follow-up period, distant metastases developed in 14.29% of cases (3 pulmonary, 2 hepatic, and 1 peritoneal) (5 pulmonary, 2 pulmonary and hepatic, and 1 peritoneal).
Conclusion
Our findings suggest that pedicled flap reconstruction following wide resection of trunk soft tissue sarcomas is associated with satisfactory outcomes (92.9% primary healing rate) and low major complication rates (7.1% Grade I–II complications). These results indicate that pedicled tissue flaps represent a viable reconstructive option when tumor clearance can be achieved.
{"title":"Retrospective cohort study on pedicled flap reconstruction after trunk soft tissue sarcoma resection: Surgical outcomes and survival analysis","authors":"Fu Laihua , Xiao Wanyi , Liu Yuanxin , Huang Jingyang , Zhou Yang , Xu Songfeng , Qiu Jin , Zhao Zhigang , Yang Jilong","doi":"10.1016/j.bjps.2025.11.012","DOIUrl":"10.1016/j.bjps.2025.11.012","url":null,"abstract":"<div><h3>Background and objective</h3><div>Although pedicled flaps are widely used in trunk reconstruction, evidence remains limited regarding their efficacy in patients with soft tissue sarcoma (STS) requiring wide resection with skeletal involvement.</div></div><div><h3>Methods</h3><div>This retrospective cohort study analyzed 42 consecutive patients who underwent pedicled flap reconstruction after trunk sarcoma resection at our institution (2019–2024). Flap types included 30 fasciocutaneous and 12 myocutaneous flaps. Outcomes included flap survival (photographic/Doppler assessment) and complications (Clavien-Dindo). Statistical analysis was performed using the Fisher's exact test and Kaplan-Meier methods (SPSS v26).</div></div><div><h3>Results</h3><div>The cohort demonstrated favorable outcomes with pedicled flap reconstruction (92.86% primary healing rate). Among skeletal defect cases, reconstructions used soft prostheses (n = 6), rigid prostheses (n = 2), or mesh reinforcement (n = 2). During the 11–59 month follow-up period, distant metastases developed in 14.29% of cases (3 pulmonary, 2 hepatic, and 1 peritoneal) (5 pulmonary, 2 pulmonary and hepatic, and 1 peritoneal)<em><strong>.</strong></em></div></div><div><h3>Conclusion</h3><div>Our findings suggest that pedicled flap reconstruction following wide resection of trunk soft tissue sarcomas is associated with satisfactory outcomes (92.9% primary healing rate) and low major complication rates (7.1% Grade I–II complications). These results indicate that pedicled tissue flaps represent a viable reconstructive option when tumor clearance can be achieved.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 227-234"},"PeriodicalIF":2.4,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.bjps.2025.10.043
Jing Qin Tay, Sheng-Lian Lee, Alfonso Orlando, David Chwei-Chin Chuang
{"title":"The thenar eminence as a reference standard for muscle flap turgor assessment in free tissue transfer for facial reanimation: A novel clinical assessment framework","authors":"Jing Qin Tay, Sheng-Lian Lee, Alfonso Orlando, David Chwei-Chin Chuang","doi":"10.1016/j.bjps.2025.10.043","DOIUrl":"10.1016/j.bjps.2025.10.043","url":null,"abstract":"","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 235-238"},"PeriodicalIF":2.4,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145625117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.bjps.2025.11.017
Ko Nakao , Masafumi Yamaga , Natsuki Kemuriyama , Eri Matoba , Hisashi Sakuma
The medial canthal region is a common site for skin cancers, and its resection often requires a concomitant lacrimal canaliculi resection. Although conventional reconstruction methods, such as dacryocystorhinostomy with placement of a Jones tube, autologous vascular grafting, and conjunctival flaps, have been used, each has notable drawbacks, including restenosis and conjunctivitis. Herein, we report a case of basal cell carcinoma of the lower eyelid in which the lower canaliculus was resected, followed by lacrimal duct reconstruction using a tubularized nasomucoperiosteal flap. A bony window was created from the tumor resection site to the nasal bone. Subsequently, a pedicled nasomucoperiosteal flap was elevated, tubularized, and anastomosed to the lower eyelid conjunctiva, allowing direct drainage of tears into the nasal cavity. At 6 months postoperatively, no complications, such as epiphora or conjunctivitis, were observed. Dacryocystography confirmed satisfactory tear drainage from the conjunctiva into the nasal cavity. This technique enables the reconstruction of a stenosis-resistant lacrimal duct using a pedicled nasomucoperiosteal flap that possesses favorable vascularity, flexibility, and adequate thickness and strength.
Lay summary
This report describes a novel technique for lacrimal duct reconstruction using a tubularized nasomucoperiosteal flap after canalicular resection for basal cell carcinoma. This method creates a durable tear drainage pathway, reducing restenosis and postoperative complications.
{"title":"Novel technique for lacrimal duct reconstruction using a tubularized nasomucoperiosteal flap","authors":"Ko Nakao , Masafumi Yamaga , Natsuki Kemuriyama , Eri Matoba , Hisashi Sakuma","doi":"10.1016/j.bjps.2025.11.017","DOIUrl":"10.1016/j.bjps.2025.11.017","url":null,"abstract":"<div><div>The medial canthal region is a common site for skin cancers, and its resection often requires a concomitant lacrimal canaliculi resection. Although conventional reconstruction methods, such as dacryocystorhinostomy with placement of a Jones tube, autologous vascular grafting, and conjunctival flaps, have been used, each has notable drawbacks, including restenosis and conjunctivitis. Herein, we report a case of basal cell carcinoma of the lower eyelid in which the lower canaliculus was resected, followed by lacrimal duct reconstruction using a tubularized nasomucoperiosteal flap. A bony window was created from the tumor resection site to the nasal bone. Subsequently, a pedicled nasomucoperiosteal flap was elevated, tubularized, and anastomosed to the lower eyelid conjunctiva, allowing direct drainage of tears into the nasal cavity. At 6 months postoperatively, no complications, such as epiphora or conjunctivitis, were observed. Dacryocystography confirmed satisfactory tear drainage from the conjunctiva into the nasal cavity. This technique enables the reconstruction of a stenosis-resistant lacrimal duct using a pedicled nasomucoperiosteal flap that possesses favorable vascularity, flexibility, and adequate thickness and strength.</div></div><div><h3>Lay summary</h3><div>This report describes a novel technique for lacrimal duct reconstruction using a tubularized nasomucoperiosteal flap after canalicular resection for basal cell carcinoma. This method creates a durable tear drainage pathway, reducing restenosis and postoperative complications.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 1-3"},"PeriodicalIF":2.4,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145555332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.bjps.2025.11.009
Daehee Jeong , William Y. Zhu , Braedon Quinlan , Mckenzie Maloney , Carl F. Schanbacher
Introduction
Nasal reconstructions are one of the most commonly performed plastic surgery procedures. The complex anatomy and critical functionality of the nose demand precise surgical approaches and planning. This is especially pertinent for subunits such as the ala. Chondrocutaneous composite grafts from the ear are excellent options for alar reconstruction, but are limited to a maximum diameter of 1.5 cm, according to historic guidelines. This study compared complication rates associated with composite grafts that are greater and smaller than the reported size limit.
Methods
A retrospective review was conducted for 53 patients who received auricular composite grafts for alar repair following Mohs micrographic surgery. Complications, including graft loss, infection, postoperative bleeding, hematoma, and functional deficits, were noted. Additionally, patients who received esthetic revisions were observed.
Results
Thirty-two grafts were <1.5 cm in diameter, and 21 were >1.5 cm in diameter. One patient had a postoperative complication, and 7 received esthetic revisional procedures. There were no significant size-dependent differences in complication rates (p = 0.396). There was a significant difference in esthetic revision rates between grafts greater than and smaller than 1.5 cm in diameter.
Conclusion
We present the first study examining the validity of using 1.5 cm as the upper diameter bound for composite grafts. Our results indicate that composite grafts are safe and effective for reconstruction of nasal ala defects >1.5 cm. These larger grafts may benefit from minor esthetic adjustments once they have healed.
鼻重建术是最常见的整形手术之一。鼻子复杂的解剖结构和关键的功能需要精确的手术方法和计划。这对于像ala这样的亚单位尤其重要。耳部软骨皮肤复合移植物是鼻翼重建的绝佳选择,但根据历史指南,其最大直径限制在1.5厘米。本研究比较了大于和小于报道尺寸限制的复合移植物的并发症发生率。方法回顾性分析53例莫氏显微摄影术后耳廓复合移植修复鼻翼的临床资料。并发症包括移植物丢失、感染、术后出血、血肿和功能缺陷。此外,还观察了接受美学修复的患者。结果移植物直径1.5 cm 32个,直径1.5 cm 21个。1例患者出现术后并发症,7例患者接受了美学修复手术。并发症发生率无明显尺寸依赖性差异(p = 0.396)。直径大于和小于1.5 cm的移植物在美观修复率上有显著差异。结论本研究首次验证了以1.5 cm为上径界作为复合移植物的有效性。结果表明,复合植体修复1.5 cm鼻翼缺损是安全有效的。这些较大的移植物在愈合后可以进行轻微的美学调整。
{"title":"Chondrocutaneous composite grafts are a viable option for nasal alar defects larger than 1.5 cm","authors":"Daehee Jeong , William Y. Zhu , Braedon Quinlan , Mckenzie Maloney , Carl F. Schanbacher","doi":"10.1016/j.bjps.2025.11.009","DOIUrl":"10.1016/j.bjps.2025.11.009","url":null,"abstract":"<div><h3>Introduction</h3><div>Nasal reconstructions are one of the most commonly performed plastic surgery procedures. The complex anatomy and critical functionality of the nose demand precise surgical approaches and planning. This is especially pertinent for subunits such as the ala. Chondrocutaneous composite grafts from the ear are excellent options for alar reconstruction, but are limited to a maximum diameter of 1.5 cm, according to historic guidelines. This study compared complication rates associated with composite grafts that are greater and smaller than the reported size limit.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted for 53 patients who received auricular composite grafts for alar repair following Mohs micrographic surgery. Complications, including graft loss, infection, postoperative bleeding, hematoma, and functional deficits, were noted. Additionally, patients who received esthetic revisions were observed.</div></div><div><h3>Results</h3><div>Thirty-two grafts were <1.5 cm in diameter, and 21 were >1.5 cm in diameter. One patient had a postoperative complication, and 7 received esthetic revisional procedures. There were no significant size-dependent differences in complication rates (<em>p</em> = 0.396). There was a significant difference in esthetic revision rates between grafts greater than and smaller than 1.5 cm in diameter.</div></div><div><h3>Conclusion</h3><div>We present the first study examining the validity of using 1.5 cm as the upper diameter bound for composite grafts. Our results indicate that composite grafts are safe and effective for reconstruction of nasal ala defects >1.5 cm. These larger grafts may benefit from minor esthetic adjustments once they have healed.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 77-84"},"PeriodicalIF":2.4,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145580129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.bjps.2025.11.014
Federica Tomaselli, Roberta Albanese, Damiano Tambasco
{"title":"Correspondence on: “Breast implant explantation with mastopexy in patients using GLP-1 receptor agonists: A retrospective comparative analysis”","authors":"Federica Tomaselli, Roberta Albanese, Damiano Tambasco","doi":"10.1016/j.bjps.2025.11.014","DOIUrl":"10.1016/j.bjps.2025.11.014","url":null,"abstract":"","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 4-5"},"PeriodicalIF":2.4,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145555333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-08DOI: 10.1016/j.bjps.2025.11.006
Shune Xiao , Miaomiao Wei , Junzhe Chen , Xiangkui Wu , Hai Li , Bihua Wu , Chengliang Deng
Purpose
Conventional therapies for postmastectomy upper extremity lymphedema often provide limited and temporary relief, especially in advanced cases. Although surgical interventions such as liposuction have improved outcomes, combining regenerative cell-based strategies with surgical volume reduction has not been systematically evaluated. This prospective study assessed the feasibility, safety, and efficacy of combining stromal vascular fraction (SVF)-gel grafting with liposuction, targeting physical debulking and lymphatic regeneration in breast cancer-related upper extremity lymphedema.
Methods
In this prospective, single-arm exploratory study, 12 patients with stage II or III breast cancer-related upper extremity lymphedema underwent liposuction followed by SVF-gel transplantation. The primary endpoint was change in excess arm volume at 12 months. Secondary outcomes included symptom severity, quality of life (QoL; Disabilities of the Arm, Shoulder and Hand [DASH] and Lymphedema Quality-of-Life Questionnaire [LYMQOL] questionnaires), incidence of cellulitis, and reliance on compression therapy. Safety was monitored throughout. Statistical analyses included repeated measures analysis of variance (ANOVA) with Bonferroni corrections, Wilcoxon, and multi-linear regression to compare changes from baseline and identify factors influencing arm volume.
Results
At 12 months, the combined intervention achieved a mean 51% reduction in excess arm volume (from 668.3 ± 275.1 to 327.5 ± 164.1 mL, P < 0.05). Significant improvements were observed in limb heaviness, tension, upper extremity function, and LYMQOL subscales (all P < 0.01). Three patients discontinued compression therapy. No cellulitis or serious adverse events occurred; minor complications resolved without intervention.
Conclusion
Combining liposuction with SVF-gel grafting is a feasible, safe, and effective approach for advanced postmastectomy upper limb lymphedema and for improving symptoms and QoL. Given the lack of published data on this combined technique, our findings lay the foundation for future controlled studies.
目的:乳房切除术后上肢淋巴水肿的常规治疗通常提供有限和暂时的缓解,特别是在晚期病例中。尽管抽脂等手术干预措施改善了结果,但将再生细胞为基础的策略与手术体积缩小相结合尚未得到系统评估。这项前瞻性研究评估了基质血管分数(SVF)凝胶移植联合吸脂治疗乳腺癌相关上肢淋巴水肿的可行性、安全性和有效性,目标是物理减容和淋巴再生。方法在这项前瞻性单臂探索性研究中,12例II期或III期乳腺癌相关上肢淋巴水肿患者行吸脂术后svf凝胶移植。主要终点是12个月时多余臂体积的变化。次要结局包括症状严重程度、生活质量(QoL;手臂、肩和手的残疾[DASH]和淋巴水肿生活质量问卷[lyqol]问卷)、蜂窝织炎的发生率和对压迫治疗的依赖。安全受到全程监控。统计分析包括使用Bonferroni校正、Wilcoxon和多元线性回归的重复测量方差分析(ANOVA),以比较基线的变化并确定影响臂体积的因素。结果12个月后,联合干预使手臂多余体积平均减少51%(从668.3±275.1 mL降至327.5±164.1 mL, P < 0.05)。在肢体重、张力、上肢功能和lyqol亚量表上观察到显著改善(P均为0.01)。3例患者停止压迫治疗。未发生蜂窝织炎或严重不良事件;轻微并发症无需干预即可解决。结论吸脂联合svf凝胶移植治疗晚期乳房切除术后上肢淋巴水肿是一种可行、安全、有效的方法,可改善患者症状和生活质量。鉴于缺乏关于这种联合技术的公开数据,我们的发现为未来的对照研究奠定了基础。
{"title":"A novel combined approach of stromal vascular fraction gel grafting and liposuction for postmastectomy upper extremity lymphedema: A prospective study","authors":"Shune Xiao , Miaomiao Wei , Junzhe Chen , Xiangkui Wu , Hai Li , Bihua Wu , Chengliang Deng","doi":"10.1016/j.bjps.2025.11.006","DOIUrl":"10.1016/j.bjps.2025.11.006","url":null,"abstract":"<div><h3>Purpose</h3><div>Conventional therapies for postmastectomy upper extremity lymphedema often provide limited and temporary relief, especially in advanced cases. Although surgical interventions such as liposuction have improved outcomes, combining regenerative cell-based strategies with surgical volume reduction has not been systematically evaluated. This prospective study assessed the feasibility, safety, and efficacy of combining stromal vascular fraction (SVF)-gel grafting with liposuction, targeting physical debulking and lymphatic regeneration in breast cancer-related upper extremity lymphedema.</div></div><div><h3>Methods</h3><div>In this prospective, single-arm exploratory study, 12 patients with stage II or III breast cancer-related upper extremity lymphedema underwent liposuction followed by SVF-gel transplantation. The primary endpoint was change in excess arm volume at 12 months. Secondary outcomes included symptom severity, quality of life (QoL; Disabilities of the Arm, Shoulder and Hand [DASH] and Lymphedema Quality-of-Life Questionnaire [LYMQOL] questionnaires), incidence of cellulitis, and reliance on compression therapy. Safety was monitored throughout. Statistical analyses included repeated measures analysis of variance (ANOVA) with Bonferroni corrections, Wilcoxon, and multi-linear regression to compare changes from baseline and identify factors influencing arm volume.</div></div><div><h3>Results</h3><div>At 12 months, the combined intervention achieved a mean 51% reduction in excess arm volume (from 668.3 ± 275.1 to 327.5 ± 164.1 mL, P < 0.05). Significant improvements were observed in limb heaviness, tension, upper extremity function, and LYMQOL subscales (all P < 0.01). Three patients discontinued compression therapy. No cellulitis or serious adverse events occurred; minor complications resolved without intervention.</div></div><div><h3>Conclusion</h3><div>Combining liposuction with SVF-gel grafting is a feasible, safe, and effective approach for advanced postmastectomy upper limb lymphedema and for improving symptoms and QoL. Given the lack of published data on this combined technique, our findings lay the foundation for future controlled studies.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 29-38"},"PeriodicalIF":2.4,"publicationDate":"2025-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145580026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-07DOI: 10.1016/j.bjps.2025.11.007
Samuel Knoedler , Florian Falkner , Marina T. Dietrich , Sarah Friedrich , Stefan O.P. Hofer , Giuseppe Sofo , Thomas Schaschinger , Gabriel Hundeshagen , Christoph Heitmann , Stefano Pompei , Dennis P. Orgill , Adriana C. Panayi , Bong-Sung Kim
Background
Although extended operative duration increases risks in other surgeries, its impact on breast reduction outcomes remains unclear. This retrospective cohort study investigated the relationship between operative time and postoperative morbidity in breast reduction.
Methods
The ACS-NSQIP database (2008–2022) was queried to identify adult female patients who underwent elective breast reduction. Preoperative, intraoperative, and postoperative parameters, including 30-day complications, were assessed. Multivariable logistic regression was used to evaluate the impact of operative time on postoperative outcomes, analyzing it as both a continuous and dichotomous variable.
Results
A total of 45,143 patients were included. Overall complications occurred in 6.4% (n=2870), with reoperation required in 1.8% (n=825) and readmission in 1.1% (n=516). Surgical complications were observed in 4.3% (n=1930), primarily superficial incisional infections (n=1466, 3.2%). Multivariable analysis demonstrated a nuanced association between operative time and complications: For every 1-h increase in operative time, the risk of any complication and surgical complications decreased by 11.4% (OR=0.998, p<0.0001) and 17.4% (OR=0.997, p<0.0001), respectively, whereas the risk of medical complications increased by 19.2% (OR=1.003, p=0.0009). Threshold analyses revealed that operative times >145 min and >147 min were associated with a significantly lower risk of any (OR=0.792, p<0.0001) and surgical complication (OR 0.708, p<0.0001), respectively. Conversely, operative times >156 min correlated with significantly higher odds of medical complications (OR=1.473, p=0.005).
Conclusion
Operative time impacts postoperative outcomes in breast reduction surgery. Longer procedures are linked to lower surgical risks but higher medical complications. Further research is needed to validate these findings and explore the underlying mechanisms.
{"title":"Time well spent? The impact of operative time on breast reduction outcomes","authors":"Samuel Knoedler , Florian Falkner , Marina T. Dietrich , Sarah Friedrich , Stefan O.P. Hofer , Giuseppe Sofo , Thomas Schaschinger , Gabriel Hundeshagen , Christoph Heitmann , Stefano Pompei , Dennis P. Orgill , Adriana C. Panayi , Bong-Sung Kim","doi":"10.1016/j.bjps.2025.11.007","DOIUrl":"10.1016/j.bjps.2025.11.007","url":null,"abstract":"<div><h3>Background</h3><div>Although extended operative duration increases risks in other surgeries, its impact on breast reduction outcomes remains unclear. This retrospective cohort study investigated the relationship between operative time and postoperative morbidity in breast reduction.</div></div><div><h3>Methods</h3><div>The ACS-NSQIP database (2008–2022) was queried to identify adult female patients who underwent elective breast reduction. Preoperative, intraoperative, and postoperative parameters, including 30-day complications, were assessed. Multivariable logistic regression was used to evaluate the impact of operative time on postoperative outcomes, analyzing it as both a continuous and dichotomous variable.</div></div><div><h3>Results</h3><div>A total of 45,143 patients were included. Overall complications occurred in 6.4% (n=2870), with reoperation required in 1.8% (n=825) and readmission in 1.1% (n=516). Surgical complications were observed in 4.3% (n=1930), primarily superficial incisional infections (n=1466, 3.2%). Multivariable analysis demonstrated a nuanced association between operative time and complications: For every 1-h increase in operative time, the risk of any complication and surgical complications decreased by 11.4% (OR=0.998, <em>p</em><0.0001) and 17.4% (OR=0.997, <em>p</em><0.0001), respectively, whereas the risk of medical complications increased by 19.2% (OR=1.003, <em>p</em>=0.0009). Threshold analyses revealed that operative times >145 min and >147 min were associated with a significantly lower risk of any (OR=0.792, <em>p</em><0.0001) and surgical complication (OR 0.708, <em>p</em><0.0001), respectively. Conversely, operative times >156 min correlated with significantly higher odds of medical complications (OR=1.473, <em>p</em>=0.005).</div></div><div><h3>Conclusion</h3><div>Operative time impacts postoperative outcomes in breast reduction surgery. Longer procedures are linked to lower surgical risks but higher medical complications. Further research is needed to validate these findings and explore the underlying mechanisms.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 211-218"},"PeriodicalIF":2.4,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-07DOI: 10.1016/j.bjps.2025.11.005
Hisako Hara , Makoto Mihara
Background
Indocyanine green (ICG) lymphography is widely used for preoperative assessment in lymphaticovenous anastomosis; however, its limited imaging depth and inability to detect vessels with impaired flow may lead to underestimation of surgical targets. Lymphatic ultrasound is a noninvasive, contrast-free modality capable of visualizing deeper lymphatic vessels and providing structural assessment. This retrospective study compared lymphatic ultrasound and ICG lymphography for detecting lymphatic vessels in patients with lower limb lymphedema.
Methods
Thirteen female patients (26 limbs; 104 areas) underwent both ICG lymphography and lymphatic ultrasound preoperatively. Each limb was divided into four regions (lateral thigh, medial thigh, medial calf, and lateral calf). The number of lymphatic vessels identified by each modality was recorded per region, and analyses were stratified by dermal backflow (DB) status on ICG lymphography.
Results
Overall, lymphatic ultrasound identified significantly more lymphatic vessels than ICG lymphography (mean ± SD: 1.9 ± 1.5 vs. 0.6 ± 0.7 vessels per area, p < 0.01). In DB-positive areas, ultrasound detected more vessels (1.9 ± 1.5) than ICG (0.3 ± 0.5, p < 0.01). In DB-negative areas also, ultrasound identified more vessels (2.0 ± 1.5) than ICG (1.1 ± 0.9, p < 0.01), except in the DB-negative lateral calf, where ICG detected more vessels. Across all the International Society of Lymphology stages, ultrasound identified more vessels; in stage 3, no vessels were detected using ICG, whereas ultrasound detected an average of 2.4 vessels per area.
Conclusions
Lymphatic ultrasound detects more lymphatic vessels than ICG lymphography, particularly in DB-positive regions and advanced stages. Negative ICG findings did not necessarily indicate the absence of lymphatic vessels. The combined use of ultrasound and ICG lymphography may broaden lymphaticovenous anastomosis eligibility and enhance preoperative planning.
背景:ICG淋巴造影术广泛应用于淋巴-静脉吻合术的术前评估;然而,它的成像深度有限,无法检测到血流受损的血管,这可能导致对手术目标的低估。淋巴管超声是一种无创、无造影剂的检查方式,能够显示更深的淋巴管并提供结构评估。本回顾性研究比较了淋巴超声和ICG淋巴造影在下肢淋巴水肿患者中检测淋巴管的效果。方法13例女性患者(26条肢体,104个部位)术前行ICG淋巴造影和淋巴超声检查。每条肢体分为四个区域(大腿外侧、大腿内侧、小腿内侧和小腿外侧)。记录每个区域通过每种方式识别的淋巴管数量,并根据ICG淋巴造影上的真皮回流(DB)状态进行分层分析。结果总体而言,淋巴超声比ICG淋巴造影发现更多的淋巴管(平均±SD: 1.9±1.5 vs. 0.6±0.7,p < 0.01)。在db阳性区,超声检出的血管数(1.9±1.5)比ICG检出的血管数(0.3±0.5,p < 0.01)多。在db阴性区域,超声也比ICG(1.1±0.9,p < 0.01)发现更多的血管(2.0±1.5),但在db阴性的小腿外侧,ICG检测到更多的血管。在国际淋巴学会的所有阶段,超声检查发现了更多的血管;在第3阶段,ICG未检测到血管,而超声平均每个区域检测到2.4条血管。结论淋巴超声比ICG淋巴造影检出更多的淋巴管,特别是在db阳性区和晚期。ICG阴性结果并不一定表明没有淋巴管。超声和ICG淋巴造影的联合应用可以拓宽淋巴-静脉吻合术的资格,加强术前规划。
{"title":"Lymphatic ultrasound detects more vessels than indocyanine green lymphography in lymphedematous limbs","authors":"Hisako Hara , Makoto Mihara","doi":"10.1016/j.bjps.2025.11.005","DOIUrl":"10.1016/j.bjps.2025.11.005","url":null,"abstract":"<div><h3>Background</h3><div>Indocyanine green (ICG) lymphography is widely used for preoperative assessment in lymphaticovenous anastomosis; however, its limited imaging depth and inability to detect vessels with impaired flow may lead to underestimation of surgical targets. Lymphatic ultrasound is a noninvasive, contrast-free modality capable of visualizing deeper lymphatic vessels and providing structural assessment. This retrospective study compared lymphatic ultrasound and ICG lymphography for detecting lymphatic vessels in patients with lower limb lymphedema.</div></div><div><h3>Methods</h3><div>Thirteen female patients (26 limbs; 104 areas) underwent both ICG lymphography and lymphatic ultrasound preoperatively. Each limb was divided into four regions (lateral thigh, medial thigh, medial calf, and lateral calf). The number of lymphatic vessels identified by each modality was recorded per region, and analyses were stratified by dermal backflow (DB) status on ICG lymphography.</div></div><div><h3>Results</h3><div>Overall, lymphatic ultrasound identified significantly more lymphatic vessels than ICG lymphography (mean ± SD: 1.9 ± 1.5 vs. 0.6 ± 0.7 vessels per area, p < 0.01). In DB-positive areas, ultrasound detected more vessels (1.9 ± 1.5) than ICG (0.3 ± 0.5, p < 0.01). In DB-negative areas also, ultrasound identified more vessels (2.0 ± 1.5) than ICG (1.1 ± 0.9, p < 0.01), except in the DB-negative lateral calf, where ICG detected more vessels. Across all the International Society of Lymphology stages, ultrasound identified more vessels; in stage 3, no vessels were detected using ICG, whereas ultrasound detected an average of 2.4 vessels per area.</div></div><div><h3>Conclusions</h3><div>Lymphatic ultrasound detects more lymphatic vessels than ICG lymphography, particularly in DB-positive regions and advanced stages. Negative ICG findings did not necessarily indicate the absence of lymphatic vessels. The combined use of ultrasound and ICG lymphography may broaden lymphaticovenous anastomosis eligibility and enhance preoperative planning.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 85-91"},"PeriodicalIF":2.4,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145580018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-07DOI: 10.1016/j.bjps.2025.11.008
Marc Daniels , Robert Jonathan Musmann , Christoph Andree , Beatrix Munder , Mazen Hagouan , Dirk Janku , Sonia Fertsch , Andreas Wolter
Introduction
Reduction mammaplasty in patients with severe macromastia poses technical challenges. In cases involving large resection volumes and long distances between the sternal notch and nipple, the risk of postoperative perfusion disturbance in the nipple-areola complex (NAC) is significantly increased. Indocyanine green (ICG) angiography has proven helpful in numerous clinical applications and can support the objective assessment of tissue perfusion which is particularly helpful in situations where vascularization is compromised, such as extreme volume reductions. We investigated whether ICG angiography can reliably detect areas of hypoperfusion, help prevent postoperative NAC necrosis and serve as a reliable decision-making tool.
Patients and methods
This prospective observational study was conducted between August 2023 and May 2025. All procedures were performed using the Double-Unit Superomedio-Central Pedicle technique. The study included adult patients with a sternal notch (SN)-to-nipple distance >35 cm. Subsequently, ICG angiography was employed to assess real-time perfusion of the NAC.
Results
The analysis included a total of 21 patients (42 breasts). The mean age of these patients was 46.3 ± 12.7 years (range 26–70 years). The mean body mass index was 31.6 ± 5.9 kg/m². The average SN-NAC distance was 40.4 ± 4.1 cm on the right and 39.6 ± 3.7 cm on the left. In this patient cohort, no necrosis of the NAC occurred, even in cases involving breasts with SN-NAC distances exceeding 50 cm and high resection weights.
Conclusion
Intraoperative ICG fluorescence angiography represents a promising tool to support surgical decision-making in reduction mammaplasty.
{"title":"Perfusion control of the nipple-areola complex in reduction plasty for gigantomastia using indocyanine green: A prospective observational study","authors":"Marc Daniels , Robert Jonathan Musmann , Christoph Andree , Beatrix Munder , Mazen Hagouan , Dirk Janku , Sonia Fertsch , Andreas Wolter","doi":"10.1016/j.bjps.2025.11.008","DOIUrl":"10.1016/j.bjps.2025.11.008","url":null,"abstract":"<div><h3>Introduction</h3><div>Reduction mammaplasty in patients with severe macromastia poses technical challenges. In cases involving large resection volumes and long distances between the sternal notch and nipple, the risk of postoperative perfusion disturbance in the nipple-areola complex (NAC) is significantly increased. Indocyanine green (ICG) angiography has proven helpful in numerous clinical applications and can support the objective assessment of tissue perfusion which is particularly helpful in situations where vascularization is compromised, such as extreme volume reductions. We investigated whether ICG angiography can reliably detect areas of hypoperfusion, help prevent postoperative NAC necrosis and serve as a reliable decision-making tool.</div></div><div><h3>Patients and methods</h3><div>This prospective observational study was conducted between August 2023 and May 2025. All procedures were performed using the <em>Double-Unit Superomedio-Central Pedicle</em> technique. The study included adult patients with a sternal notch (SN)-to-nipple distance >35 cm. Subsequently, ICG angiography was employed to assess real-time perfusion of the NAC.</div></div><div><h3>Results</h3><div>The analysis included a total of 21 patients (42 breasts). The mean age of these patients was 46.3 ± 12.7 years (range 26–70 years). The mean body mass index was 31.6 ± 5.9 kg/m². The average SN-NAC distance was 40.4 ± 4.1 cm on the right and 39.6 ± 3.7 cm on the left. In this patient cohort, no necrosis of the NAC occurred, even in cases involving breasts with SN-NAC distances exceeding 50 cm and high resection weights.</div></div><div><h3>Conclusion</h3><div>Intraoperative ICG fluorescence angiography represents a promising tool to support surgical decision-making in reduction mammaplasty.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 177-185"},"PeriodicalIF":2.4,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-06DOI: 10.1016/j.bjps.2025.11.003
Marco Gratteri , Giovanni Francesco Marangi , Fara Desiree Romano , Felicia Geanina Grosu , Daniela Porso , Andrea Tarantino , Luigi Abate , Riccardo De Bernardis , Annalisa Cogliandro , Paolo Persichetti
Introduction
Ptosis is a common complication after reduction mammoplasty, but its main influencing factors remain unclear. We aimed to evaluate the roles of age, smoking, pregnancies, hypertension, diabetes, preoperative glandular composition, stretch marks, Fitzpatrick skin type, weight change, Ribeiro flap usage, resected tissue weight, and preoperative and postoperative breast volume on breast droop within the first year after surgery.
Materials and methods
Overall, 127 women who consecutively underwent reduction mammoplasty within 3 years took part in this study. Previously cited recorded data were noted and exported in Prism10 for correlation analysis with two indexes of breast ptosis: sternal notch-nipple and nipple-inframammary fold T12-T1 deltas.
Results
For breast ptosis, the major influencing positive factors were age, postsurgery breast volume, stretch mark score, estimated preoperative major glandular composition of the breast, and delta weight. Smoking history and diabetes mellitus correlate in a moderate manner. Pregnancy weakly positively correlated with breast ptosis, whereas preoperative breast volume, resected breast weight, and Fitzpatrick skin type did not correlate with the investigated indexes. The only factor that negatively correlated with breast ptosis indexes was the usage of Ribeiro flap.
Conclusion
Breast ptosis after reduction mammoplasty is strongly correlated with age, postsurgery breast volume, stretch mark score, estimated preoperative major glandular composition of the breast, and delta weight in the first year after surgery. Other influencing factors were smoking history, diabetes mellitus, and history of pregnancy. The Ribeiro flap proved to have a protective role.
{"title":"Nine factors influencing breast ptosis following reduction mammoplasty","authors":"Marco Gratteri , Giovanni Francesco Marangi , Fara Desiree Romano , Felicia Geanina Grosu , Daniela Porso , Andrea Tarantino , Luigi Abate , Riccardo De Bernardis , Annalisa Cogliandro , Paolo Persichetti","doi":"10.1016/j.bjps.2025.11.003","DOIUrl":"10.1016/j.bjps.2025.11.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Ptosis is a common complication after reduction mammoplasty, but its main influencing factors remain unclear. We aimed to evaluate the roles of age, smoking, pregnancies, hypertension, diabetes, preoperative glandular composition, stretch marks, Fitzpatrick skin type, weight change, Ribeiro flap usage, resected tissue weight, and preoperative and postoperative breast volume on breast droop within the first year after surgery.</div></div><div><h3>Materials and methods</h3><div>Overall, 127 women who consecutively underwent reduction mammoplasty within 3 years took part in this study. Previously cited recorded data were noted and exported in Prism10 for correlation analysis with two indexes of breast ptosis: sternal notch-nipple and nipple-inframammary fold T12-T1 deltas.</div></div><div><h3>Results</h3><div>For breast ptosis, the major influencing positive factors were age, postsurgery breast volume, stretch mark score, estimated preoperative major glandular composition of the breast, and delta weight. Smoking history and diabetes mellitus correlate in a moderate manner. Pregnancy weakly positively correlated with breast ptosis, whereas preoperative breast volume, resected breast weight, and Fitzpatrick skin type did not correlate with the investigated indexes. The only factor that negatively correlated with breast ptosis indexes was the usage of Ribeiro flap.</div></div><div><h3>Conclusion</h3><div>Breast ptosis after reduction mammoplasty is strongly correlated with age, postsurgery breast volume, stretch mark score, estimated preoperative major glandular composition of the breast, and delta weight in the first year after surgery. Other influencing factors were smoking history, diabetes mellitus, and history of pregnancy. The Ribeiro flap proved to have a protective role.</div></div>","PeriodicalId":50084,"journal":{"name":"Journal of Plastic Reconstructive and Aesthetic Surgery","volume":"113 ","pages":"Pages 129-137"},"PeriodicalIF":2.4,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145625261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}