Pub Date : 2023-11-01DOI: 10.1136/jitc-2023-sitc2023.1451
Theoni Katopodi, Yin Xin Ho, Charlotte Bell, Lyndsey Hanson, Amy Cantrell, Emily Wright, Nick Moore, Stewart Brown, Lorraine Mooney, Jane Kendrew
{"title":"1451 The implantation site impacts the tumour growth kinetics and tumour immune infiltrate in EO771 and 4T1 syngeneic breast cancer models","authors":"Theoni Katopodi, Yin Xin Ho, Charlotte Bell, Lyndsey Hanson, Amy Cantrell, Emily Wright, Nick Moore, Stewart Brown, Lorraine Mooney, Jane Kendrew","doi":"10.1136/jitc-2023-sitc2023.1451","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.1451","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.1136/jitc-2023-sitc2023.0182
Xiaopeng Sun, Brandie C Taylor, Margaret Axelrod, Lamorna Swigart, Laura van ‘t Veer, Gillian Hirst, Justin M Balko
{"title":"182 Peripheral immunological features as predictors of breast cancer chemoimmunotherapy response","authors":"Xiaopeng Sun, Brandie C Taylor, Margaret Axelrod, Lamorna Swigart, Laura van ‘t Veer, Gillian Hirst, Justin M Balko","doi":"10.1136/jitc-2023-sitc2023.0182","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.0182","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.1136/jitc-2023-sitc2023.0886
Luis Vence, Radhika Rayanki, Tao Deng, Mohamed Moustafa, Sonia Iyer, Marta Milo, Lydia Greenlees, Steve Arbitman, Arthur Lambert, Giulia Fabbri, Raffaello Cimbro, Gemma Jones, Douglas C Palmer, Patricia McCoon
{"title":"886 <i>In vitro</i>study of the effects of ceralasertib (AZD6738) on the tumor microenvironment cell populations","authors":"Luis Vence, Radhika Rayanki, Tao Deng, Mohamed Moustafa, Sonia Iyer, Marta Milo, Lydia Greenlees, Steve Arbitman, Arthur Lambert, Giulia Fabbri, Raffaello Cimbro, Gemma Jones, Douglas C Palmer, Patricia McCoon","doi":"10.1136/jitc-2023-sitc2023.0886","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.0886","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"1186 Engineering bispecific dual-antagonist antibodies for novel cancer therapies","authors":"Ankita Srivastava, Tracy Charlton, Ranveer Jayani, Omer Keinan, Arvin Akoopie, Jonah Rainey, Jacek Ostrowski","doi":"10.1136/jitc-2023-sitc2023.1186","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.1186","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.1136/jitc-2023-sitc2023.0745
Dafne CA Quixabeira, Santeri A Pakola, James Clubb, Lyna Haybout, Elise Jirovec, Tatiana Kudling, Joao Santos, Victor Cervera-Carrascon, Katriina Peltola, Tuomo Alanko, Jorma Sormunen, Riitta Korpisaari, Marjut Jaakkola, Juha Kononen, Susanna Juteau, Claudia Kistler, Suvi Sorsa, Riikka Havunen, Akseli Hemminki
{"title":"745 Immune cell profiling of advanced-stage solid tumors patients treated with an oncolytic adenovirus encoding for TNF-a and IL-2 (TILT-123)","authors":"Dafne CA Quixabeira, Santeri A Pakola, James Clubb, Lyna Haybout, Elise Jirovec, Tatiana Kudling, Joao Santos, Victor Cervera-Carrascon, Katriina Peltola, Tuomo Alanko, Jorma Sormunen, Riitta Korpisaari, Marjut Jaakkola, Juha Kononen, Susanna Juteau, Claudia Kistler, Suvi Sorsa, Riikka Havunen, Akseli Hemminki","doi":"10.1136/jitc-2023-sitc2023.0745","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.0745","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.1136/jitc-2023-sitc2023.0362
Duncan Howie, Terri V Cornforth, Nathifa Moyo, Suzanne Cole, Emily Lam, Tatiana Lobry, Ron Wolchinsky, Angharad Lloyd, Katarzyna Ward, Eleanor M Denham, Gurdyal S Besra, Patricia Illing, Bruce MacLachlan, Julian Vivian, Jeremy Raynes, Jerome Le Nours, Anthony Purcell, Samit Kundu, Jonathan D Silk, Luke Williams, Sophie Papa, Jamie Rossjohn, Joseph Dukes
{"title":"362 Allelic variants of MR1 drive cancer and allo-reactivity by MR1-restricted T cells","authors":"Duncan Howie, Terri V Cornforth, Nathifa Moyo, Suzanne Cole, Emily Lam, Tatiana Lobry, Ron Wolchinsky, Angharad Lloyd, Katarzyna Ward, Eleanor M Denham, Gurdyal S Besra, Patricia Illing, Bruce MacLachlan, Julian Vivian, Jeremy Raynes, Jerome Le Nours, Anthony Purcell, Samit Kundu, Jonathan D Silk, Luke Williams, Sophie Papa, Jamie Rossjohn, Joseph Dukes","doi":"10.1136/jitc-2023-sitc2023.0362","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.0362","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.1136/jitc-2023-sitc2023.0117
Aditya Pratapa, Ning Ma, Lorcan Sherry, Matthew MacFarlane, Gabriel Reines March, Niyati Jhaveri, Najiba Mammadova
{"title":"117 Ultrahigh-plex to high-throughput spatial phenotyping: an integrated pathway from discovery to translational and clinical studies","authors":"Aditya Pratapa, Ning Ma, Lorcan Sherry, Matthew MacFarlane, Gabriel Reines March, Niyati Jhaveri, Najiba Mammadova","doi":"10.1136/jitc-2023-sitc2023.0117","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.0117","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.1136/jitc-2023-sitc2023.0190
Shelby Knoche, Indu Venugopal, Michael J McGuire, Kathlynn C Brown
{"title":"190 Utilizing a peptide-based approach to target and evaluate novel biomarker Neu5Gc Sialyl Lewis A in cancer","authors":"Shelby Knoche, Indu Venugopal, Michael J McGuire, Kathlynn C Brown","doi":"10.1136/jitc-2023-sitc2023.0190","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.0190","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.1136/jitc-2023-sitc2023.1396
Meghan M Verstraete, Maya Poffenberger, Matteo Zago, Veronica Luu, Brenda Ma, Nichole Escalante, Janessa Li, Diego Perez Escanda, Siran Cao, Edward Meier, Sifa Arrafi, Yun Peng, Anna Von Rossum, Genevieve Desjardins, Nina Weisser, Thomas Spreter von Kreudenstein
{"title":"1396 TriTCE CPI: a novel trispecifc T cell engager platform with integrated PD-1/PD-L1 checkpoint inhibition engineered for the treatment of immunosuppressed tumors","authors":"Meghan M Verstraete, Maya Poffenberger, Matteo Zago, Veronica Luu, Brenda Ma, Nichole Escalante, Janessa Li, Diego Perez Escanda, Siran Cao, Edward Meier, Sifa Arrafi, Yun Peng, Anna Von Rossum, Genevieve Desjardins, Nina Weisser, Thomas Spreter von Kreudenstein","doi":"10.1136/jitc-2023-sitc2023.1396","DOIUrl":"https://doi.org/10.1136/jitc-2023-sitc2023.1396","url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：