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A Comprehensive Analysis of the Future of Atomically Precise Manufacturing 全面分析原子精度制造的未来
Pub Date : 2024-09-02 DOI: arxiv-2409.00955
Vadym Shvydun, Justin Sato, Gabriel Bristot
Atomically Precise Manufacturing (APM) refers to the assembly of materialswith atomic precision, representing a highly advanced technology withsignificant potential. However, the development of APM remains in its earlystages, with applications largely confined to specialized fields and lackingcohesion within a unified discipline. The current literature on APM is oftendominated by older, speculative papers that discuss its immense potential risksand benefits without sufficient grounding in the latest advancements orpractical limitations that exist today. This paper aims to bridge this gap byproviding a comprehensive assessment of current APM and near-APM technologies,as well as using the barriers to further progress to predict futuredevelopments. Through this analysis, we seek to establish a clearerunderstanding of the present state of the technology and then use theseinsights to predict the future trajectory of APM. By doing so, we aim to createa more grounded discourse on APM and its potential risks and benefits, whilealso guiding future research on the necessary regulations and safetyconsiderations for this emerging field.
原子精密制造(APM)是指以原子精度组装材料,是一项极具潜力的先进技术。然而,原子精密制造的发展仍处于早期阶段,其应用主要局限于专业领域,缺乏统一学科的凝聚力。目前有关 APM 的文献往往以较早的、推测性的论文为主,这些论文讨论的是 APM 潜在的巨大风险和益处,而没有充分立足于当今存在的最新进展或实际限制。本文旨在弥合这一差距,对当前的 APM 和近 APM 技术进行全面评估,并利用进一步发展的障碍来预测未来的发展。通过分析,我们力求对技术现状有一个清晰的认识,然后利用这些认识来预测 APM 的未来发展轨迹。通过这样做,我们的目标是就杀伤人员地雷及其潜在风险和益处展开更有依据的讨论,同时指导未来对这一新兴领域的必要法规和安全考虑因素的研究。
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引用次数: 0
Healthcare system resilience and adaptability to pandemic disruptions in the United States 美国医疗保健系统对大流行病破坏的复原力和适应力
Pub Date : 2024-09-02 DOI: arxiv-2409.01454
Lu Zhong, Dimitri Lopez, Sen Pei, Jianxi Gao
Understanding healthcare system resilience has become paramount, particularlyin the wake of the COVID-19 pandemic, which imposed unprecedented burdens onhealthcare services and severely impacted public health. Resilience is definedas the system's ability to absorb, recover from, and adapt to disruptions;however, despite extensive studies on this subject, we still lack empiricalevidence and mathematical tools to quantify its adaptability (the ability ofthe system to adjust to and learn from disruptions). By analyzing millions ofpatients' electronic medical records across US states, we find that theCOVID-19 pandemic caused two successive waves of disruptions within thehealthcare systems, enabling natural experiment analysis of the adaptivecapacity for each system to adapt to past disruptions. We generalize thequantification framework and find that the US healthcare systems exhibitsubstantial adaptability but only a moderate level of resilience. Whenconsidering system responses across racial groups, Black and Hispanic groupswere more severely impacted by pandemic disruptions than White and Asiangroups. Physician abundance is the key characteristic for determininghealthcare system resilience. Our results offer vital guidance in designingresilient and sustainable healthcare systems to prepare for future waves ofdisruptions akin to COVID-19 pandemics.
了解医疗保健系统的适应能力已变得至关重要,尤其是在 COVID-19 大流行之后,它给医疗保健服务带来了前所未有的负担,并严重影响了公众健康。恢复力被定义为系统吸收、恢复和适应中断的能力;然而,尽管对这一主题进行了广泛的研究,我们仍然缺乏经验证据和数学工具来量化其适应性(系统适应中断并从中学习的能力)。通过分析美国各州数百万患者的电子病历,我们发现 COVID-19 大流行在医疗保健系统中连续引发了两波干扰,从而可以通过自然实验分析每个系统适应过去干扰的适应能力。我们对量化框架进行了归纳,发现美国医疗保健系统表现出了很强的适应能力,但复原力仅处于中等水平。在考虑不同种族群体的系统反应时,黑人和西班牙裔群体受到大流行病破坏的影响比白人和亚裔群体更为严重。医生数量是决定医疗系统应变能力的关键特征。我们的研究结果为设计有弹性和可持续发展的医疗保健系统提供了重要指导,以便为未来类似于 COVID-19 大流行的破坏浪潮做好准备。
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引用次数: 0
Supervised Pattern Recognition Involving Skewed Feature Densities 涉及倾斜特征密度的有监督模式识别
Pub Date : 2024-09-02 DOI: arxiv-2409.01213
Alexandre Benatti, Luciano da F. Costa
Pattern recognition constitutes a particularly important task underlying agreat deal of scientific and technologica activities. At the same time, patternrecognition involves several challenges, including the choice of features torepresent the data elements, as well as possible respective transformations. Inthe present work, the classification potential of the Euclidean distance and adissimilarity index based on the coincidence similarity index are compared byusing the k-neighbors supervised classification method respectively to featuresresulting from several types of transformations of one- and two-dimensionalsymmetric densities. Given two groups characterized by respective densitieswithout or with overlap, different types of respective transformations areobtained and employed to quantitatively evaluate the performance of k-neighborsmethodologies based on the Euclidean distance an coincidence similarity index.More specifically, the accuracy of classifying the intersection point betweenthe densities of two adjacent groups is taken into account for the comparison.Several interesting results are described and discussed, including the enhancedpotential of the dissimilarity index for classifying datasets with right skewedfeature densities, as well as the identification that the sharpness of thecomparison between data elements can be independent of the respectivesupervised classification performance.
模式识别是一项特别重要的任务,是大量科技活动的基础。与此同时,模式识别也面临着一些挑战,包括如何选择特征来表示数据元素,以及可能的相应转换。在本研究中,通过使用 k-neighbors 监督分类方法,分别比较了欧氏距离和基于重合相似性指数的相似性指数的分类潜力,以及一维和二维不对称密度的几种变换所产生的特征。给定两个组的特征是各自的密度没有重叠或有重叠,我们得到了各自不同类型的变换,并采用这些变换来定量评估基于欧氏距离和重合相似性指数的 k-邻居方法的性能。文中描述和讨论了几个有趣的结果,包括提高了不相似性指数对特征密度向右倾斜的数据集进行分类的潜力,以及发现数据元素间比较的锐度可以独立于相关的监督分类性能。
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引用次数: 0
Modelling the High-Voltage Grid Using Open Data for Europe and Beyond 利用开放数据为欧洲及其他地区的高压电网建模
Pub Date : 2024-08-30 DOI: arxiv-2408.17178
Bobby Xiong, Davide Fioriti, Fabian Neumann, Iegor Riepin, Tom Brown
This paper provides the background, methodology and validation forconstructing a representation of the European high-voltage grid, including andabove 200 kV, based on public data provided by OpenStreetMap. Themodel-independent grid dataset is published under the Open Data Commons OpenDatabase (ODbL 1.0) licence and can be used for large-scale electricity as wellas energy system modelling. The dataset and workflow are provided as part ofPyPSA-Eur -- an open-source, sector-coupled optimisation model of the Europeanenergy system. By integrating with the codebase for initiatives such asPyPSA-Earth, the value of open and maintainable high-voltage grid data extendsto the global context. By accessing the latest data through the the Overpassturbo API, the dataset can be easily reconstructed and updated within minutes.To assess the data quality, this paper further compares the dataset withofficial statistics and representative model runs using PyPSA-Eur based ondifferent electricity grid representations.
本文基于 OpenStreetMap 提供的公共数据,介绍了构建欧洲高压电网(包括 200 千伏及以上)的背景、方法和验证。该独立于模型的电网数据集根据开放数据共享开放数据库(ODbL 1.0)许可发布,可用于大规模电力和能源系统建模。该数据集和工作流程作为欧洲能源系统开源部门耦合优化模型 PyPSA-Eur 的一部分提供。通过与 PyPSA-Earth 等计划的代码库集成,开放和可维护的高压电网数据的价值扩展到了全球范围。通过 Overpassturbo API 访问最新数据,可以在几分钟内轻松重建和更新数据集。为了评估数据质量,本文进一步将数据集与官方统计数据以及使用 PyPSA-Eur 基于不同电网表示的代表性模型运行进行了比较。
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引用次数: 0
Exaptation: Academic mentees' career pathway to be independent and impactful 适应:学术导师的职业发展之路,成为独立而有影响力的人
Pub Date : 2024-08-30 DOI: arxiv-2408.16992
Yanmeng Xing, Ye Sun, Tongxin Pan, Xianglong Liang, Giacomo Livan, Yifang Ma
In science, mentees often follow their mentors' career paths, but exceptionalmentees frequently break from this routine, sometimes even outperforming theirmentors. However, the pathways to independence for these excellent mentees andtheir interactions with mentors remain unclear. We analyzed the careers of over500,000 mentees in Chemistry, Neuroscience, and Physics over the past 60 yearsto examine the strategies mentees employ in selecting research topics relativeto their mentors, how these strategies evolve, and their resulting impact.Utilizing co-citation network analysis and a topic-specific impact allocationalgorithm, we mapped the topic territory for each mentor-mentee pair andquantified their academic impact accrued within the topic. Our findings revealmentees tend to engage with their mentors' less-dominated topics and explorenew topics at the same time, and through this exaptive process, they begin toprogressively establish their own research territories. This trend isparticularly pronounced among those who outperform their mentors. Moreover, weidentified an inverted U-shaped curve between the extent of topic divergenceand the mentees' long-term impact, suggesting a moderate divergence from thementors' research focus optimizes the mentees' academic impact. Finally, alongthe path to independence, increased coauthorship with mentors impedes thementees' impact, whereas extending their collaboration networks with thementors' former collaborators proves beneficial. These findings fill a crucialgap in understanding how mentees' research topic selection strategies affectacademic success and offer valuable guidance for early-career researchers onpursuing independent research paths.
在科学领域,被指导者通常会沿着导师的职业道路前进,但优秀的被指导者往往会打破这种常规,有时甚至会超越导师。然而,这些优秀被指导者实现独立的途径以及他们与指导者之间的互动仍不清楚。我们分析了化学、神经科学和物理学领域过去 60 年里 50 多万名被指导者的职业生涯,研究了被指导者相对于指导者在选择研究课题时所采用的策略、这些策略是如何演变的,以及由此产生的影响。我们的研究结果表明,被指导者倾向于参与指导者不太主导的课题,同时探索新的课题,通过这一适应过程,他们开始逐步建立自己的研究领地。这种趋势在那些表现优于导师的学生中尤为明显。此外,我们还发现,课题分歧程度与被指导者的长期影响力之间存在倒 U 型曲线,这表明,与指导者研究重点的适度分歧能优化被指导者的学术影响力。最后,在通往独立的道路上,与导师增加合作会阻碍被指导者的影响力,而与导师的前合作者扩大合作网络则证明是有益的。这些发现填补了人们在了解被指导者的研究选题策略如何影响学术成功方面的一个重要空白,并为早期研究人员走上独立研究之路提供了宝贵的指导。
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引用次数: 0
Cartographie du confort thermique au sein d'une cours d'{é}cole parisienne : couplage de mesures microclimatiques fixes et mobiles 绘制巴黎一所学校庭院的热舒适度图:将固定和移动微气候测量相结合
Pub Date : 2024-08-30 DOI: arxiv-2409.00148
Ghid KaramLIED, Maïlys ChanialLIED, Maxime ChaumontLIED, Martin HendelLIED, Laurent Royon
Climate change will result in more frequent, more intense and longer-lastingheat waves by 2050. As part of its Climate Plan and its resilience strategy,the City of Paris is deploying, through its Oasis program, a network of urbancool islands to mitigate the urban heat island phenomena: schoolyards arerenovated in order to reduce the heat stress of users. We establish amethodology aiming to quantify the microclimatic impact of the transformation.Mobile measurements are carried out within a case courtyard under hotconditions and coupled with fixed weather station data to evaluate heat stressusing UTCI. The heat stress mapping thus obtained allows a first microclimaticdiagnosis of the schoolyard.
到 2050 年,气候变化将导致更频繁、更强烈和更持久的热浪。作为其气候计划和抗灾战略的一部分,巴黎市正在通过 "绿洲 "计划部署一个城市凉岛网络,以缓解城市热岛现象:对学校操场进行改造,以减轻使用者的热压力。我们建立了一套方法,旨在量化改造对小气候的影响。在炎热条件下,在案例庭院内进行移动测量,并与固定气象站数据相结合,利用 UTCI 评估热应力。由此获得的热应力分布图可对学校操场进行首次微气候诊断。
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引用次数: 0
Autocorrelation properties of temporal networks governed by dynamic node variables 受动态节点变量支配的时空网络的自相关特性
Pub Date : 2024-08-29 DOI: arxiv-2408.16270
Harrison Hartle, Naoki Masuda
We study synthetic temporal networks whose evolution is determined bystochastically evolving node variables - synthetic analogues of, e.g., temporalproximity networks of mobile agents. We quantify the long-timescalecorrelations of these evolving networks by an autocorrelative measure of edgepersistence. Several distinct patterns of autocorrelation arise, includingpower-law decay and exponential decay, depending on the choice of node-variabledynamics and connection probability function. Our methods are also applicablein wider contexts; our temporal network models are tractable mathematically andin simulation, and our long-term memory quantification is analyticallytractable and straightforwardly computable from temporal network data.
我们研究了由随机演化的节点变量决定其演化的合成时空网络--即移动代理的时空邻近性网络等的合成类似物。我们通过边缘持久性的自相关度量来量化这些演化网络的长时间尺度相关性。根据节点变量动力学和连接概率函数的选择,会出现几种不同的自相关模式,包括幂律衰减和指数衰减。我们的方法也适用于更广泛的场合;我们的时空网络模型在数学上和模拟上都是可行的,我们的长期记忆量化在分析上是可行的,并且可以直接从时空网络数据中计算出来。
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引用次数: 0
Typical daily profiles of PM concentrations in parisian underground railway stations 巴黎地铁站 PM 浓度的典型日分布图
Pub Date : 2024-08-29 DOI: arxiv-2409.08291
Valisoa RakotonirinjanaharyPC2A, Suzanne CrumeyrolleLOA, Mateusz BogdanPC2A, Benjamin HanounePC2A
To enhance the understanding of air quality within underground railwaystations (URS), a methodology has been developed to establish a baselineprofile of particle concentrations (PM10 and PM2.5). This approach incorporatesan extensive data cleaning process based on the identification of URS operationperiods, physically inconsistent or mathematically aberrant data, and comparingthe profile of each day to an average profile. The versatility of thismethodology allows its application to different particle classes within variousURS. The results obtained from the three studied URS indicate the possibilityof obtaining reliable daily typical profiles even over short measurementperiods (up to one or two weeks).
为了加强对地下铁道站(URS)内空气质量的了解,我们开发了一种方法来建立颗粒物浓度(PM10 和 PM2.5)的基准剖面图。这种方法包含一个广泛的数据清理过程,其基础是识别 URS 运行期、物理上不一致或数学上异常的数据,并将每天的剖面图与平均剖面图进行比较。这种方法的多功能性使其适用于各种 URS 中的不同颗粒类别。从所研究的三个 URS 中获得的结果表明,即使在较短的测量期内(最长一到两周),也有可能获得可靠的每日典型剖面图。
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引用次数: 0
Healthcare Utilization Patterns Among Migrant Populations: Increased Readmissions Suggest Poorer Access. A Population-Wide Retrospective Cohort Study 流动人口的医疗保健使用模式:再入院次数增加表明就医条件较差。全人群回顾性队列研究
Pub Date : 2024-08-29 DOI: arxiv-2408.16317
Elma Dervić, Ola Ali, Carola Deischinger, Rafael Prieto-Curiel, Rainer Stütz, Ellenor Mittendorfer-Rutz, Peter Klimek
Equal access to health ensures that all citizens, regardless ofsocio-economic status, can achieve optimal health, leading to a moreproductive, equitable, and resilient society. Yet, migrant populations werefrequently observed to have lower access to health. The reasons for this arenot entirely clear and may include language barriers, a lack of knowledge ofthe healthcare system, and selective migration (a "healthy migrant" effect). Weuse extensive medical claims data from Austria (13 million hospital stays ofapproximately 4 million individuals) to compare the healthcare utilizationpatterns between Austrians and non-Austrians. We looked at the differences inprimary diagnoses and hospital sections of initial hospital admission acrossdifferent nationalities. We hypothesize that cohorts experiencing the healthymigrant effect show lower readmission rates after hospitalization compared tomigrant populations that are in poorer health but show lower hospitalizationrates due to barriers in access. We indeed find that all nationalities showedlower hospitalization rates than Austrians, except for Germans, who exhibit asimilar healthcare usage to Austrians. Although around 20% of the populationhas a migration background, non-Austrian citizens account for only 9.4% of thehospital patients and 9.79% of hospital nights. However, results forreadmission rates are much more divergent. Nationalities like Hungary, Romania,and Turkey (females) show decreased readmission rates in line with the healthymigrant effect. Patients from Russia, Serbia, and Turkey (males) show increasedreadmissions, suggesting that their lower hospitalization rates are more likelydue to access barriers. Considering the surge in migration, our findings shedlight on healthcare access and usage behaviours across patients with differentnationalities, offering new insights and perspectives.
平等获得保健服务可确保所有公民,无论其社会经济地位如何,都能获得最佳健康状况,从而建设一个生产力更高、更公平、更有韧性的社会。然而,人们经常发现,流动人口获得医疗服务的机会较少。其原因尚不完全清楚,可能包括语言障碍、缺乏对医疗保健系统的了解以及选择性移民("健康移民 "效应)。我们利用奥地利的大量医疗索赔数据(约 400 万人的 1300 万次住院),比较了奥地利人和非奥地利人的医疗保健使用模式。我们研究了不同国籍的人在初次入院时的主要诊断和住院科室方面的差异。我们假设,与健康状况较差但因就医障碍而住院率较低的移民人群相比,经历了健康移民效应的人群住院后的再入院率较低。我们确实发现,除德国人外,所有民族的住院率都低于奥地利人,德国人的医疗保健使用情况与奥地利人相似。虽然约 20% 的人口有移民背景,但非奥地利公民仅占住院病人的 9.4% 和住院天数的 9.79%。然而,住院率的结果却大相径庭。匈牙利、罗马尼亚和土耳其(女性)等国家的再入院率有所下降,这与健康移民效应相符。而来自俄罗斯、塞尔维亚和土耳其的患者(男性)的再入院率则有所上升,这表明他们较低的住院率更有可能是由于就医障碍造成的。考虑到移民人数的激增,我们的研究结果揭示了不同国籍患者获得和使用医疗服务的行为,为我们提供了新的见解和视角。
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引用次数: 0
Recent Decade's Power Outage Data Reveals the Increasing Vulnerability of U.S. Power Infrastructure 最近十年的停电数据揭示了美国电力基础设施日益严重的脆弱性
Pub Date : 2024-08-28 DOI: arxiv-2408.15882
Bo Li, Junwei Ma, Femi Omitaomu, Ali Mostafavi
Despite significant anecdotal evidence regarding the vulnerability of theU.S. power infrastructure, there is a dearth of longitudinal and nation-levelcharacterization of the spatial and temporal patterns in the frequency andextent of power outages. A data-driven national-level characterization of poweroutage vulnerability is particularly essential for understanding the urgencyand formulating policies to promote the resilience of power infrastructuresystems. Recognizing this, we retrieved 179,053,397 county-level power outagerecords with a 15-minute interval across 3,022 US counties during 2014-2023 tocapture power outage characteristics. We focus on three dimensions--poweroutage intensity, frequency, and duration--and develop multiple metrics toquantify each dimension of power outage vulnerability. The results show that inthe past ten years, the vulnerability of U.S. power system has consistentlybeen increasing. Counties experienced an average of 999.4 outages over thedecade, affecting an average of more than 540,000 customers per county, withdisruptions occurring approximately every week. Coastal areas, particularly inCalifornia, Florida and New Jersey, faced more frequent and prolonged outages,while inland regions showed higher outage rates. A concerning increase inoutage frequency and intensity was noted, especially after 2017, with a sharprise in prolonged outages since 2019. The research also found positiveassociation between social vulnerability and outage metrics, with theassociation becoming stronger over the years under study. Areas with highersocial vulnerability experienced more severe and frequent outages, exacerbatingchallenges in these regions. These findings reveal the much-needed empiricalevidence for stakeholders to inform policy formulation and program developmentfor enhancing the resilience of the U.S. power infrastructure.
尽管有大量轶事证明美国电力基础设施的脆弱性,但缺乏对停电频率和范围的空间和时间模式的纵向和国家级描述。数据驱动的国家级停电脆弱性特征描述对于了解促进电力基础设施系统恢复能力的紧迫性和制定相关政策尤为重要。有鉴于此,我们检索了 2014-2023 年间美国 3022 个县的 17905397 条县级停电记录(间隔时间为 15 分钟),以捕捉停电特征。我们重点关注三个维度--停电强度、频率和持续时间--并制定了多个指标来量化停电脆弱性的每个维度。结果表明,在过去十年中,美国电力系统的脆弱性持续上升。十年间,各县平均经历了 999.4 次停电,平均每个县影响超过 54 万用户,大约每周发生一次停电。沿海地区,尤其是加利福尼亚州、佛罗里达州和新泽西州的停电频率更高、时间更长,而内陆地区的停电率则更高。研究发现,停电频率和强度的增加令人担忧,尤其是在 2017 年之后,自 2019 年以来,长时间停电的情况急剧增加。研究还发现,社会脆弱性与停电指标之间存在正相关关系,而且这种关系随着研究年份的增加而变得更加紧密。社会脆弱性较高的地区经历了更严重、更频繁的停电,加剧了这些地区的挑战。这些研究结果为利益相关者提供了亟需的经验证据,为政策制定和项目开发提供了依据,以增强美国电力基础设施的恢复能力。
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引用次数: 0
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