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Postoperative Distal Enteral Tube Refeeding in Stoma Patients: A Comparative Analysis of Clinical Outcomes. 造口患者术后远端肠管再喂养:临床结果对比分析。
Pub Date : 2023-10-17 DOI: 10.5604/01.3001.0053.9351
Jignesh Gandhi, Aadrika Kashyap, Pravin Shinde

<b><br>Introduction:</b> Stoma surgery, which involves creating a diversion of the small intestine through an abdominal wall opening, poses challenges in managing fluid and electrolyte imbalances. Patients with high proximal stoma often rely on costly and risky parenteral nutrition (PN). Distal enteral tube feeding, a method of delivering nutrition to the small intestine, is intended to improve clinical outcomes and reduce complications. This study presents a comparative analysis of clinical outcomes between postoperative distal enteral tube refeeding and traditional enteral and PN approaches in stoma patients with distal mucous fistula.</br> <b><br>Aim:</b> To evaluate the effectiveness of distal enteral tube refeeding in improving postoperative outcomes after stoma surgery and to examine the impact of distal enteral tube refeeding on total hospitalization stay, ICU length of stay, TPN duration, and time to closure of the stoma.</br> <b><br>Material and methods:</b> The study is a retrospective, single-center trial involving 84 patients who had undergone stoma surgery. The patients were divided into two groups: those receiving postoperative distal enteral tube refeeding (n = 42) and the control group (n = 42), with standard mucous fistula creation. The data was collected retrospectively from January 2012 to January 2022 and the statistical analysis was performed using descriptive statistics, the chi-square test, and the t-test.</br> <b><br>Results:</b> The results of our study show that the patients who had undergone postoperative distal enteral tube refeeding had a significantly shorter total hospitalization stay (p = 0.0002), a significantly shorter ICU length of stay (p = 0.0006), a significantly shorter TPN duration (p= 0.0004), and a significantly faster time to closure (p = 0.0002).</br>.

<b><br>引言:</b> 造口手术涉及通过腹壁开口将小肠改道,给液体和电解质失衡的管理带来了挑战。高位造口患者通常需要依赖昂贵且高风险的肠外营养(PN)。远端肠管喂养是一种向小肠输送营养的方法,旨在改善临床效果并减少并发症。本研究对患有远端粘液瘘的造口患者术后远端肠管再喂养与传统肠内和肠外营养方法的临床疗效进行了比较分析。</br><b><br>材料和方法:</b>该研究是一项回顾性单中心试验,涉及 84 名接受造口手术的患者。患者分为两组:术后接受远端肠管再喂养组(42 人)和对照组(42 人),对照组采用标准粘液造瘘术。数据收集时间为 2012 年 1 月至 2022 年 1 月,采用描述性统计、卡方检验和 t 检验进行统计分析。
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引用次数: 0
Testicular and scrotal abnormalities in pediatric and adult patients. 儿童和成人患者的睾丸和阴囊异常。
Pub Date : 2023-10-17 DOI: 10.5604/01.3001.0053.9349
Patrycja Sosnowska-Sienkiewicz, Danuta Januszkiewicz-Lewandowska, Przemysław Mańkowski

Testicular and scrotal abnormalities can occur in children, adolescents, and adults. The lesions, often accompanied by pain and swelling/enlargement of the scrotum, can cause anxiety in patients and their parents. Regardless of age, proper diagnosis is based on adequate anamnesis and physical examination. Color Doppler ultrasound is the first-line test in the differential process of testicular and scrotal diseases. Testicular and scrotal lesions require differentiation for benign and malignant processes as well as therapeutic management, including urgent surgical intervention. The aim of this paper is to present the most common causes of testicular and scrotal abnormalities in pediatric and adult patients and to outline the symptoms and diagnostic and therapeutic management.

睾丸和阴囊异常可发生在儿童、青少年和成年人身上。病变通常伴有疼痛和阴囊肿胀/增大,会让患者及其父母感到焦虑。无论年龄大小,正确的诊断都要以充分的病史和体格检查为基础。在鉴别睾丸和阴囊疾病的过程中,彩色多普勒超声是第一线检查。睾丸和阴囊病变需要区分良性和恶性过程,并进行治疗处理,包括紧急手术干预。本文旨在介绍儿童和成人患者睾丸和阴囊异常的最常见原因,并概述其症状、诊断和治疗方法。
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引用次数: 0
Modified optical port entry site for laparoscopic cholecystectomy: Our experience. 腹腔镜胆囊切除术的改良光学端口入口:我们的经验
Pub Date : 2023-10-17 DOI: 10.5604/01.3001.0053.9350
Pravin Shinde, Aarsh Gajjar, Rajiv Karvande

<b><br>Introduction:</b> The four-port laparoscopic cholecystectomy is a recognized entity in the surgical management of gallstone disease. We report our experience and feasibility of optical port entry site modification.</br> <b><br>Material and Methods:</b> To assess the feasibility and safety of laparoscopic cholecystectomy with a different port placement, we undertook a prospective study with 60 patients at Seth GSMC and KEM Hospital, India between Jan 2022 and July 2022. Our study offered the benefit of a flexible optical port entry site, using a 5 mm optical trocar instead of the conventional 10 mm trocar. A single surgeon did all the cases and definite criteria of simple cases of gallstone disease patterned on clinical and radiological grounds.</br> <b><br>Results:</b> 60 cases of gallstone disease were subjected to the new technique of laparoscopic cholecystectomy over seven months. 39 cases were females and 21 were males. The age range of our patients was between 20 and 55 years with a median age of 39 years. Mean Body mass index 30 (range 25 - 37). The mean operative time was 30 min (range 15 - 45 min) and a follow-up period ranged from 10 to 14 months. No cases were converted to open. We did not encounter any untoward mishaps during surgery.</br> <b><br>Discussion:</b> Our modification of the optical port placement and size received good results and patient satisfaction. Moreover, the placement of the port at a site further from the midline and umbilicus decreases the risk of development of trocar site incisional hernia.</br>.

<b><br>引言:</b>四孔腹腔镜胆囊切除术是公认的胆石症外科治疗方法。</br><b><br>材料与方法:</b>为了评估使用不同端口位置进行腹腔镜胆囊切除术的可行性和安全性,我们在 2022 年 1 月至 2022 年 7 月期间在印度 Seth GSMC 和 KEM 医院对 60 名患者进行了前瞻性研究。我们的研究使用 5 毫米光学套管代替传统的 10 毫米套管,提供了灵活的光学端口进入部位的优势。所有病例均由一名外科医生完成,并根据临床和放射学依据制定了简单胆石症病例的明确标准。其中 39 例为女性,21 例为男性。患者年龄介于 20 岁至 55 岁之间,中位年龄为 39 岁。平均体重指数为 30(25 - 37)。平均手术时间为 30 分钟(15 - 45 分钟不等),随访时间为 10 - 14 个月不等。没有病例转为开腹手术。我们在手术过程中没有遇到任何意外事故。</br> <b><br>讨论:</b> 我们对光学端口位置和大小的修改取得了良好的效果,病人也很满意。此外,将光导口放置在离中线和脐部更远的位置可降低发生套管部位切口疝的风险。
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引用次数: 0
Retrospective analysis of treatment, including access to breast reconstructions, of breast cancer patients - war refugees from Ukraine in Poland - the experience of a single tertiary care institution. 回顾性分析乳腺癌患者的治疗,包括获得乳房重建的机会——来自乌克兰的战争难民在波兰——单一三级医疗机构的经验。
Pub Date : 2023-03-15
Thomas Wow, Dawid Murawa, Katarzyna Boguszewska-Byczkiewicz, Jacek Burzyński, Aleksandra Ryk, Agnieszka Kolacinska

<b>Introduction:</b> Following the Russian invasion, more than 3600000 refugees have fled Ukraine and settled down in Poland; this group includes a growing number of breast cancer patients whose treatment had been started in Ukraine and hence required urgent therapy in Poland.</br></br> <b>Aim:</b> The aim of the study was to analyze the treatment of breast cancer patients from Ukraine, who entered Poland as war refugees - the experience of a single tertiary care institution.</br></br> <b>Material and methods:</b> The treatment of 25 consecutive breast cancer patients, war refugees from Ukraine was reviewed retrospectively.</br></br> <b>Results:</b> Patients were treated according to subtype and staging, e.g. surgery, endocrine, anti-HER2 therapy, chemotherapy, radiotherapy. 7 patients received an immediate implant, mesh-based breast reconstruction. In 2 cases, the patients refused breast reconstruction.</br></br> <b>Conclusions:</b> Nearly 5.5 million refugees across Europe who have fled the combat zones in Ukraine; of these, the vast majority sought shelter in Poland, and many of whom are women. It is expected that breast cancer mortality rates may rise and progress in oncology may slow as the war in Ukraine disrupts routine patient care, clinical trials and research. Hence, support from neighboring countries is mandatory.

& lt; b>介绍:& lt; / b>在俄罗斯入侵之后,超过360万难民逃离乌克兰,在波兰定居;这一群体包括越来越多的乳腺癌患者,他们在乌克兰开始治疗,因此需要在波兰进行紧急治疗。& lt; b>目的:& lt; / b>该研究的目的是分析作为战争难民进入波兰的乌克兰乳腺癌患者的治疗-单一三级医疗机构的经验。</br>材料和方法:</b>回顾性分析25例乌克兰战争难民乳腺癌患者的治疗情况。</br></br>& lt; b>结果:& lt; / b>根据患者的亚型和分期进行手术、内分泌、抗her2治疗、化疗、放疗等治疗。7例患者接受了立即植入,网状乳房重建。2例患者拒绝乳房重建。</br> /br>& lt; b>结论:& lt; / b>欧洲各地逃离乌克兰战区的近550万难民;其中绝大多数人在波兰寻求庇护,其中许多是妇女。由于乌克兰战争扰乱了常规的病人护理、临床试验和研究,预计乳腺癌死亡率可能会上升,肿瘤学的进展可能会放缓。因此,邻国的支援是强制性的。
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引用次数: 0
The preventive effect of omega-3 fish oil on the formation of peritoneal adhesions. ω-3鱼油对腹膜粘连形成的预防作用。
Pub Date : 2023-02-17 DOI: 10.5604/01.3001.0016.2730
Kerem Karaman, Hüseyin Çakıroğlu, Fatıma Betül Tuncer, Mehmet Ramazan Şekeroğlu, Fahri Yılmaz

<br><b>Introduction:</b> Postoperative peritoneal adhesions that form after abdominal surgery still continue to exist as an unresolved health problem.</br> <br><b>Aim:</b> The aim of the study is to examine whether omega-3 fish oil has a preventive effect on postoperative peritoneal adhesions.</br> <br><b>Material and methods:</b> Twenty-one female Wistar albino rats were separated into 3 groups (sham, control and experimental), each consisting of 7 rats. In the sham group, only laparotomy was performed. In both the control and experimental group rats, the right parietal peritoneum and cecum were traumatised to form petechiae. Following this procedure, the abdomen was irrigated with omega-3 fish oil in the experimental group. The rats were re-explored on the 14<sup>th</sup> postoperative day and any adhesions were scored. Tissue samples and blood samples were taken for histopathological and biochemical analysis.</br> <br><b>Results:</b> None of the rats that were administered omega-3 fish oil developed macroscopic postoperative peritoneal adhesions (P = 0.005). The omega-3 fish oil formed an anti-adhesive lipid barrier on the injured tissue surfaces. Microscopic evaluation revealed diffuse inflammation with excessive connective tissue and fibroblastic activity in the control group rats, while foreign body reactions were common in the omega-3 rats. The mean amount of hydroxyproline in samples from injured tissues was significantly lower in the omega-3 rats than in the control rats (P = 0.004).</br> <br><b>Conclusion:</b> Intraperitoneal application of omega-3 fish oil prevents postoperative peritoneal adhesions by forming an anti-adhesive lipid barrier on injured tissue surfaces. However, further studies are needed to determine whether this adipose layer is permanent or will be resorbed over time.</br>.

</br><b>引言:</b>腹部手术后形成的腹膜粘连仍是一个尚未解决的健康问题。</br><br><b>目的:</b>本研究旨在探讨欧米伽-3鱼油是否对术后腹膜粘连有预防作用。</br></br><b>材料和方法:</b>21 只雌性 Wistar 白化大鼠分为 3 组(假组、对照组和实验组),每组 7 只。假组只进行开腹手术。对照组和实验组大鼠的右腹膜旁和盲肠都受到创伤,形成瘀斑。手术后,用欧米茄-3 鱼油冲洗实验组大鼠的腹部。术后第 14<sup>th</sup> 天再次对大鼠进行检查,并对粘连情况进行评分。采集组织样本和血液样本进行组织病理学和生化分析。</br> <br><b>结果:</b> 服用欧米伽-3 鱼油的大鼠术后均未出现大面积腹膜粘连(P = 0.005)。欧米伽-3鱼油在受伤组织表面形成了抗粘连脂质屏障。显微镜评估显示,对照组大鼠存在弥漫性炎症,结缔组织和成纤维细胞活性过强,而欧米伽-3组大鼠则普遍存在异物反应。损伤组织样本中羟脯氨酸的平均含量在欧米伽-3组大鼠中明显低于对照组大鼠(P = 0.004)</br><br><b>结论:</b>腹腔内应用欧米伽-3鱼油可通过在损伤组织表面形成抗粘连脂质屏障来预防术后腹腔粘连。不过,要确定这种脂肪层是永久性的还是会随着时间的推移而被吸收,还需要进一步的研究。
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引用次数: 0
Anastomotic Leak in Colorectal Surgery: Predictive Factors and Survival. 结直肠手术中的吻合口漏:预测因素与存活率。
Pub Date : 2022-12-20 DOI: 10.5604/01.3001.0016.1602
Swetha Prabhakaran, Sowmya Prabhakaran, Wei Mou Lim, Glen Guerra, Alexander G Heriot, Joseph C Kong

<br><b>Introduction:</b> Anastomotic leak (AL) is a serious complication following colorectal surgery.</br> <br><b>Aim:</b> The aim of this study was to identify factors associated with the development of AL and to analyze its impact on survival.</br> <br><b>Materials and methods:</b> All consecutive adult colorectal cancer resections performed between 2007 and 2020 with curative intent and anastomosis formation were included from a prospectively maintained database. The primary outcome measure was the rate of AL. The secondary outcome measure was 5-year overall survival (OS).</br> <br><b>Results:</b> There were 6837 eligible patients. The rate of AL was 2.2% and 4.0% in patients with colon and rectal cancer, respectively. AL was a significant independent predictor of reduced 5-year OS in patients who underwent curative surgery for rectal cancer (odds ratio 2.293, p = 0.009). Emergency surgery (p = 0.015), surgery at a public hospital (p = 0.002), and an open surgical approach (p = 0.021) were all associated with a significantly higher risk of AL in patients with colon cancer, with higher rates of AL noted in left colectomies as compared to right hemicolectomies (4.4% <i>vs.</i> 1.3%, p < 0.001). In rectal cancer patients, AL was associated with neoadjuvant chemoradiotherapy (p = 0.038) and male gender (p = 0.002). The anastomosis formation technique (hand-sewn <i>vs.</i> stapled) did not impact the rate of AL (p = 0.116 and p = 0.198 with colon and rectal cancer, respectively).</br> <br><b>Discussion:</b> Clinicians should be cognizant of the predictive factors for AL and should consider early intervention for at-risk patients.</br>.

</br><b>引言:</b>吻合口漏(AL)是结直肠手术后的一种严重并发症。</br></br><b>材料和方法:</b>所有在 2007 年至 2020 年期间进行的连续性成人结直肠癌切除术均来自于一个前瞻性维护的数据库,这些切除术均以治愈为目的并形成了吻合。主要结果指标是AL率。次要结局指标是 5 年总生存率 (OS)。</br> <br><b>结果:</b> 共有 6837 名符合条件的患者。结肠癌和直肠癌患者的AL率分别为2.2%和4.0%。在接受直肠癌根治性手术的患者中,AL是降低5年生存率的重要独立预测因素(几率比2.293,P = 0.009)。急诊手术(p = 0.015)、公立医院手术(p = 0.002)和开放手术方式(p = 0.021)都与结肠癌患者发生 AL 的风险显著升高有关,左半结肠切除术与右半结肠切除术相比,AL 发生率更高(4.4% <i>vs.</i> 1.3%,p <0.001)。在直肠癌患者中,AL与新辅助化放疗(p = 0.038)和男性性别(p = 0.002)有关。吻合口形成技术(手缝<i>vs.</i>钉合)对 AL 的发生率没有影响(结肠癌和直肠癌的发生率分别为 p = 0.116 和 p = 0.198)</br><br><b>讨论:</b>临床医生应了解 AL 的预测因素,并应考虑对高危患者进行早期干预</br>.
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引用次数: 0
Dupuytren's disease - what's new: a review. Dupuytren氏病——最新进展:综述。
Pub Date : 2022-10-24 DOI: 10.5604/01.3001.0016.0058
Andrzej Żyluk

<b><br>Introduction:</b> Dupuytren's disease is a common fibrotic disorder of the palmar aponeurosis characterized by the formation of nodules and cords, as well as development of progressive flexion deformities in the digits, leading to functional impairment. Surgical excision of the affected aponeurosis remains the most common treatment. Quite a few new information appeared about epidemiology, pathogenesis and particularly treatment of the disorder.</br> <b><br>Aim:</b> The aim of this study is an updated review of scientific data in this topic.</br> <b><br>Results:</b> Results of epidemiologic studies showed that Dupuytren's disease is not so uncommon in Asian and African population as it was earlier believed. An important role of genetic factors on development of the disease in a proportion of patients was demonstrated, however, it did not translate neither to the treatment nor to the prognosis. The most changes concerned the management of Dupuytren's disease. A positive effect of steroids injections into the nodules and cords for inhibition of the disease in early stages was shown. In the advanced stages, a standard technique of partial fasciectomy was partly replaced by mini-invasive methods such as needle fasciotomy and collagenase Clostirdium hystolyticum injections. Unexpected withdrawal of collagenase from the market in 2020 resulted in considerable limitation of the availability of this treatment.</br> <b><br>Conclusion:</b> It seems that updated knowledge on Dupuytren's disease may be interested and useful for surgeons involved in management of the disorder.</br>.

& lt; b> & lt; br>简介:& lt; / b>Dupuytren病是一种常见的掌腱膜纤维化疾病,其特征是结节和索的形成,以及手指进行性屈曲畸形的发展,导致功能障碍。手术切除受影响的腱膜仍然是最常见的治疗方法。关于该病的流行病学、发病机制,特别是治疗方面出现了不少新信息。& lt; b> & lt; br>目的:& lt; / b>本研究的目的是对这一主题的科学数据进行最新的回顾。</br>& lt; b> & lt; br>结果:& lt; / b>流行病学研究结果表明,Dupuytren病在亚洲和非洲人群中并不像以前认为的那样罕见。遗传因素在一部分患者的疾病发展中发挥了重要作用,然而,它既没有转化为治疗,也没有转化为预后。最大的变化涉及到Dupuytren病的治疗。在早期阶段,向结节和索内注射类固醇对疾病的抑制有积极作用。在晚期,部分筋膜切除术的标准技术部分被微创方法取代,如针筋膜切开术和胶原酶注射。2020年,胶原酶意外从市场上撤出,导致这种治疗方法的可获得性受到相当大的限制。& lt; b> & lt; br>结论:& lt; / b>似乎关于Dupuytren病的最新知识可能对参与治疗该疾病的外科医生感兴趣和有用。</ brgt。
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引用次数: 0
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Polski przeglad chirurgiczny
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