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Effect of preoperative intragastric balloon treatment on perioperative and postoperative outcomes after laparoscopic sleeve gastrectomy: A retrospective cohort study. 术前胃内球囊治疗对腹腔镜袖带胃切除术围手术期和术后效果的影响:一项回顾性队列研究。
Pub Date : 2024-02-08 DOI: 10.5604/01.3001.0054.2675
Anna Rzepa, Izabela Karpińska, Mateusz Wierdak, Magdalena Pisarska-Adamczyk, Tomasz Stefura, Ilona Kawa, Michał Pędziwiatr, Piotr Major

<b><br>Introduction:</b> Intragastric balloon (IGB) insertion is used as a bridging therapy in patients with body mass index (BMI) ≥ 50 kg/m2 . We arranged a retrospective study to evaluate whether pre-operative IGB treatment influences perioperative and postoperative weight loss outcomes after laparoscopic sleeve gastrectomy (SG), and especially to evaluate the impact of post - IGB percentage of excessive weight loss (%EWL) on postoperative %EWL.</br> <b><br>Materials and methods:</b> Patients who underwent IGB placement followed by laparoscopic SG were divided into the following groups considering %EWL after IGB: Group 1 <=10.38%; Group 2 >10.38% and <=17.27%; Group 3 >17.27% and <=24.86%; Group 4 >24.86%. 1 year after SG data were collected. The following parameters were compared between groups: operative time, total blood loss, length of stay and weight, BMI, percentage of total weight loss (%TWL), %EWL.</br> <b><br>Results:</b> There were no statistically significant differences between groups in perioperative results. Post-SG %EWL was the highest in intermediate groups: 2 and 3. Post-treatment results were observed: body weight and BMI were the lowest in Group 4 and the highest in Group 1. Post-treatment %EWL was the highest in Group 4, the lowest in Group 1 and grew gradually in subsequent groups.</br> <b><br>Discussion:</b> The study confirmed the impact of weight loss on IGB on postoperative results. The study showed that %EWL after the IGB treatment influences %EWL after SG and most of all affects definitive %EWL after two-stage treatment and it could be a foreshadowing factor of these outcomes.</br> <b><br>Importance:</b> The importance of research for the development of the field %EWL after IGB influences the final BMI and final weight, which means that patients with the greatest %EWL after IGB are more likely to have the greatest postoperative weight loss and overall weight loss.</br>.

<b><br>引言:</b>胃内球囊(IGB)植入被用作体重指数(BMI)≥ 50 kg/m2 患者的桥接疗法。我们安排了一项回顾性研究,以评估术前 IGB 治疗是否会影响腹腔镜袖带胃切除术(SG)的围术期和术后体重减轻结果,尤其是评估 IGB 术后体重减轻过多百分比(%EWL)对术后体重减轻百分比的影响。</br><b><br>材料和方法:</b>根据 IGB 后体重减轻百分比将接受 IGB 置入术和腹腔镜 SG 的患者分为以下几组:第 1 组<=10.38%;第 2 组<10.38% 和<=17.27%;第 3 组<17.27% 和<=24.86%;第 4 组<24.86%。收集 SG 1 年后的数据。各组间比较了以下参数:手术时间、总失血量、住院时间、体重、BMI、总体重减轻百分比(%TWL)、%EWL。SG后的EWL%在中间组2和3中最高。观察治疗后的结果:体重和 BMI 在第 4 组最低,在第 1 组最高;治疗后 %EWL 在第 4 组最高,在第 1 组最低,并在随后的各组中逐渐增加。研究表明,IGB 治疗后的体重减轻率会影响 SG 治疗后的体重减轻率,最主要的是会影响两期治疗后的明确体重减轻率,这可能是这些结果的预示因素。
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引用次数: 0
Preliminary results of Polish national multicenter LILEO study on ileostomy reversal. 波兰全国多中心 LILEO 回肠造口术逆转研究的初步结果。
Pub Date : 2024-02-08 DOI: 10.5604/01.3001.0054.2679
Michał Kisielewski, Michał Wysocki, Tomasz Stefura, Tomasz Wojewoda, Kamil Safiejko, Mateusz Wierdak, Tomasz Sachanbiński, Michał Jankowski, Karol Tkaczyński, Karolina Richter, Wojciech Wysocki

<b><br>Introduction:</b> Ileostomy reversal is a common surgical procedure and currently standardized perioperative and surgical protocols are lacking.</br> <b><br>Aim:</b> LILEO study was designed to perform a multicenter analysis on numerous perioperative parameters and estimation of the incidence of postoperative complications.</br> <b><br>Materials and methods:</b> The study is an open multicenter prospective cohort study. Preliminary results of the LILEO study after 3 months were available from 18 Polish surgical centers comprising full data of 59 patients who underwent ileostomy reversal.</br> <b><br>Results:</b> Parameters such as preoperative care, surgical technique, postoperative course and complications were analyzed. Preoperative fasting was used in 49.1% of patients. Fifty nine percent of anastomosis were handsewn and in 72.9% of patients had primary single suture wound closure. Mean length of hospital stay was 7.9 days (min 2 days, max 26 days). Complications occurred overall in 20 patients (33.9%). In 11.9% of patient's complications had grade III A/B in Clavien-Dindo classification.</br> <b><br>Discussion:</b> The perioperative care in the group of patients undergoing ileostomy reversal still lacks standardized and optimized treatment.</br> <b><br>Conclusions:</b> Ileostomy removal is a procedure with high risk of postoperative complications. Standardization of perioperative care based on further multicenter national study could result in a decrease of complications rate.</br>.

</br><br>简介:</b>回肠造口术翻转是一种常见的外科手术,目前缺乏标准化的围手术期和手术方案。波兰 18 家外科中心提供了 LILEO 研究 3 个月后的初步结果,包括 59 名接受回肠造口术翻转术患者的全部数据。49.1%的患者术前禁食。59%的吻合术采用手工缝合,72.9%的患者采用单线缝合。平均住院时间为 7.9 天(最短 2 天,最长 26 天)。20名患者(33.9%)出现并发症。根据 Clavien-Dindo 分级,11.9% 患者的并发症为 III A/B 级。</br> <b><br>讨论:</b> 回肠造口翻转术患者的围手术期护理仍然缺乏标准化和优化的治疗。</br><b><br>结论:</b>回肠造口术是一种术后并发症风险较高的手术。基于进一步的多中心全国性研究的围手术期标准化护理可降低并发症发生率。
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引用次数: 0
Colorectal Cancer: Is it Still a Disease of the Elderly? 大肠癌:大肠癌还是老年人的疾病吗?
Pub Date : 2023-12-14 DOI: 10.5604/01.3001.0054.0956
Renata Kędzia-Berut, Maciej Berut, Marcin Włodarczyk, Jakub Włodarczyk, Łukasz Dziki, Adam Dziki, Michał Mik

<b><br>Introduction:</b> Colorectal cancer is becoming an increasingly significant health issue, being one of the more commonly diagnosed malignancies. Colorectal tumors account for 10% of all malignant cancers in women and 12% in men. Incidence is higher in the male population, especially among younger individuals. It is commonly believed that colorectal cancer is predominantly associated with advanced age. However, colorectal surgeons, who specialize in the treatment of this type of cancer, are observing a growing number of cases among middle-aged and younger individuals.</br> <b><br>Aim:</b> The aim of our study was to investigate whether colorectal cancer still predominantly affects elderly individuals, how frequently it is diagnosed in younger patients, and whether the location of tumors in the intestines of younger patients aligns with data from elderly individuals.</br> <b><br>Materials and methods:</b> The study was conducted retrospectively and included a cohort of 1771 patients who underwent surgical procedures due to colorectal cancer between 2012 and 2015 at the Department of General and Colorectal Surgery at the Medical University of Łódź and between 2014 and 2017 at the Department of General Surgery with a Division of Surgical Oncology at the District Health Center in Brzeziny. Data were analyzed regarding the frequency of colorectal cancer occurrence by age, tumor location in different age groups, and disease stage according to age. Age groups included <40 years, 41-50 years, 51-70 years, and >70 years.</br> <b><br>Results:</b> The study encompassed a total of 1771 patients, with 988 (55.79%) being males and 783 (44.21%) females. The mean age of the patients was 65.27 11.12 years. The highest number of cases was observed in the age range of 60-70 years and 70-80 years. It was found that colorectal tumors in males more frequently occurred on the left side of the colon and rectum, while in females, they were more commonly located on the right side of the colon, which was statistically significant (P = 0.007). Younger age groups of patients (<40 years, 40-50 years) had a similar male-to-female ratio, whereas in age groups above 50 years, males significantly outnumbered females (P = 0.049). The study revealed that in the group of patients below 40 years of age, an advanced stage of colorectal cancer was significantly more common; stage D occurred over twice as often as in the 51-70 age group and over three times as often as in the >70 age group.</br> <b><br>Conclusions:</b> The incidence of colorectal cancer in Poland is steadily increasing, with a growing number of diagnoses in younger individuals. Research findings demonstrate that males, especially those in younger age groups, are at a higher risk of developing colorectal cancer. A higher disease stage is more frequently observed in younger patients, po

<b><br>简介:</b>结直肠癌是较常见的恶性肿瘤之一,正日益成为一个重要的健康问题。结直肠肿瘤占女性恶性肿瘤的 10%,占男性恶性肿瘤的 12%。男性发病率较高,尤其是年轻人。人们普遍认为,结直肠癌主要与高龄有关。但是,专门治疗这类癌症的结直肠外科医生发现,中年和年轻人的病例越来越多。</br> <b><br></b>目的:</b> 我们的研究旨在调查结直肠癌是否仍然主要影响老年人,年轻患者被诊断出结直肠癌的频率如何,以及年轻患者肠道中肿瘤的位置是否与老年人的数据一致。</br><b><br>材料与方法:</b>研究采用回顾性方法,纳入了2012年至2015年间在罗兹医科大学普通外科和结直肠外科系以及2014年至2017年间在Brzeziny地区卫生中心普通外科和肿瘤外科系接受结直肠癌手术治疗的1771名患者。数据分析涉及按年龄划分的结直肠癌发生频率、不同年龄组的肿瘤位置以及按年龄划分的疾病分期。年龄组包括 40 岁、41-50 岁、51-70 岁和 70 岁。患者的平均年龄为 65.27 11.12 岁。60-70 岁和 70-80 岁年龄段的病例数最多。研究发现,男性结直肠肿瘤多发生在结肠和直肠的左侧,而女性结直肠肿瘤多发生在结肠的右侧,这在统计学上有显著意义(P = 0.007)。年轻年龄组(40 岁、40-50 岁)患者的男女比例相似,而在 50 岁以上年龄组中,男性明显多于女性(P = 0.049)。研究显示,在 40 岁以下的患者群体中,结直肠癌晚期的发生率明显更高;D 期的发生率是 51-70 岁年龄组的两倍多,是 70 岁年龄组的三倍多。研究结果表明,男性,尤其是年轻男性罹患结直肠癌的风险更高。年轻患者的疾病分期更高,这可能是由于延迟诊断和对症治疗造成的。筛查计划应根据高风险年龄组的变化进行调整。我们的研究强调,有必要提高公众对结直肠癌的认识,尤其是在年轻人群中。
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引用次数: 0
Artificial intelligence assistance in deciding management strategies for polytrauma and trauma patients. 人工智能协助决定多发性创伤和创伤患者的管理策略。
Pub Date : 2023-11-24 DOI: 10.5604/01.3001.0053.9857
Chayanin Angthong, Naruebade Rungrattanawilai, Chaiyapruk Pundee

<b><br>Introduction:</b> Artificial intelligence (AI) is an emerging technology with vast potential for use in several fields of medicine. However, little is known about the application of AI in treatment decisions for patients with polytrauma. In this systematic review, we investigated the benefits and performance of AI in predicting the management of patients with polytrauma and trauma.</br> <b><br>Methods:</b> This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies were extracted from the PubMed and Google Scholar databases from their inception until November 2022, using the search terms "Artificial intelligence," "polytrauma," and "decision." Seventeen articles were identified and screened for eligibility. Animal studies, review articles, systematic reviews, meta-analyses, and studies that did not involve polytrauma or severe trauma management decisions were excluded. Eight studies were eligible for final review.</br> <b><br>Results:</b> Eight studies focusing on patients with trauma, including two on military trauma, were included. The AI applications were mainly implemented for predictions and/or decisions on shock, bleeding, and blood transfusion. Few studies predicted death/survival. The identification of trauma patients using AI was proposed in a previous study. The overall performance of AI was good (six studies), excellent (one study), and acceptable (one study).</br> <b><br>Discussion:</b> AI demonstrated satisfactory performance in decision-making and management prediction in patients with polytrauma/severe trauma, especially in situations of shock/bleeding.</br> <b><br>Importance:</b> The present study serves as a basis for further research to develop practical AI applications for the management of patients with trauma.</br>.

<b><br>引言:</b>人工智能(AI)是一项新兴技术,在多个医学领域具有巨大的应用潜力。然而,人们对人工智能在多发性创伤患者治疗决策中的应用知之甚少。在这篇系统综述中,我们研究了人工智能在预测多发性创伤和外伤患者管理方面的益处和性能。使用 "人工智能"、"多创伤 "和 "决策 "等检索词,从 PubMed 和 Google Scholar 数据库中提取了从开始到 2022 年 11 月的研究。确定了 17 篇文章,并对其进行了资格筛选。排除了动物研究、综述文章、系统综述、荟萃分析以及不涉及多发性创伤或严重创伤管理决策的研究。八项研究符合最终审查条件。</br> <b><br>结果:</b> 八项研究的重点是创伤患者,包括两项关于军事创伤的研究。人工智能应用主要用于预测和/或决定休克、出血和输血。预测死亡/存活的研究很少。之前的一项研究提出使用人工智能识别创伤患者。人工智能的总体表现为良好(6 项研究)、优秀(1 项研究)和可接受(1 项研究)</br> <b><br>讨论:</b> 人工智能在多发性创伤/严重创伤患者的决策和管理预测方面表现令人满意,尤其是在休克/出血的情况下。</br><b><br>重要性:</b>本研究为进一步研究人工智能在创伤患者管理中的实际应用奠定了基础。
{"title":"Artificial intelligence assistance in deciding management strategies for polytrauma and trauma patients.","authors":"Chayanin Angthong, Naruebade Rungrattanawilai, Chaiyapruk Pundee","doi":"10.5604/01.3001.0053.9857","DOIUrl":"10.5604/01.3001.0053.9857","url":null,"abstract":"<p><p>&lt;b&gt;&lt;br&gt;Introduction:&lt;/b&gt; Artificial intelligence (AI) is an emerging technology with vast potential for use in several fields of medicine. However, little is known about the application of AI in treatment decisions for patients with polytrauma. In this systematic review, we investigated the benefits and performance of AI in predicting the management of patients with polytrauma and trauma.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Methods:&lt;/b&gt; This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies were extracted from the PubMed and Google Scholar databases from their inception until November 2022, using the search terms \"Artificial intelligence,\" \"polytrauma,\" and \"decision.\" Seventeen articles were identified and screened for eligibility. Animal studies, review articles, systematic reviews, meta-analyses, and studies that did not involve polytrauma or severe trauma management decisions were excluded. Eight studies were eligible for final review.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Results:&lt;/b&gt; Eight studies focusing on patients with trauma, including two on military trauma, were included. The AI applications were mainly implemented for predictions and/or decisions on shock, bleeding, and blood transfusion. Few studies predicted death/survival. The identification of trauma patients using AI was proposed in a previous study. The overall performance of AI was good (six studies), excellent (one study), and acceptable (one study).&lt;/br&gt; &lt;b&gt;&lt;br&gt;Discussion:&lt;/b&gt; AI demonstrated satisfactory performance in decision-making and management prediction in patients with polytrauma/severe trauma, especially in situations of shock/bleeding.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Importance:&lt;/b&gt; The present study serves as a basis for further research to develop practical AI applications for the management of patients with trauma.&lt;/br&gt.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"96 0","pages":"114-117"},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Necrotizing fasciitis - two case reports and literature review. 坏死性筋膜炎--两例病例报告和文献综述。
Pub Date : 2023-11-24 DOI: 10.5604/01.3001.0053.9501
Bartosz Molasy, Mateusz Frydrych

<b><br>Introduction:</b> Necrotizing fasciitis (NF) is a rare, rapidly progressing infection of the skin and subcutaneous tissue. NF can lead to massive tissue necrosis, resulting in sepsis, septic shock and death. In this disease, it is important to quickly diagnose and implement appropriate treatment.</br> <b><br>Aim:</b> Analysis of the diagnostic and therapeutic process in two clinical cases and a review of the literature on the methods of diagnosis and treatment of necrotizing fasciitis.</br> <b><br>Material and methods:</b> The medical data of two patients hospitalized in the St Alexander Hospital in Kielce from December 2022 to June 2023 due to necrotizing fasciitis were analyzed. Also literature search across PubMed, Medline and Research Gate databases from 2000 up to 2023 was performed. We reviewed English literature according to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. The following keywords were used: necrotizing fasciitis, etiopathogenesis, pathophysiology, management.</br> <b><br>Results:</b> The research group consisted of two male patients with NF after trauma, in different parts of the body. Based on the clinical examination, the results of laboratory and imaging tests, a diagnosis was made and appropriate treatment was initiated. Despite the applied treatment, one patient died as a result of progressive multiple organ failure.</br> <b><br>Conclusions:</b> Despite advances in diagnosis and treatment, including universal access to antibiotics, necrotizing fasciitis still cause high mortality. The microbiological complexity of the majority of cases and non-specific symptoms make the diagnostic and therapeutic process difficult. Taking into account necrotizing fasciitis each time in the differential diagnosis of inflammation of the skin and subcutaneous tissue, especially based on trauma, will allow to reduce morbidity and mortality in this disease.</br>.

<b><br>简介:</b> 坏死性筋膜炎(NF)是一种罕见的、进展迅速的皮肤和皮下组织感染。NF 可导致大量组织坏死,引起败血症、脓毒性休克和死亡。</br><b><br><br>目的:</b>分析两例临床病例的诊断和治疗过程,并对有关坏死性筋膜炎诊断和治疗方法的文献进行综述。</br><b><br>材料与方法:</b>分析了2022年12月至2023年6月因坏死性筋膜炎在凯尔采圣亚历山大医院住院的两名患者的医疗数据。此外,我们还在PubMed、Medline和Research Gate数据库中进行了2000年至2023年的文献检索。我们根据《系统综述和元分析首选报告项目》(PRISMA)指南对英文文献进行了综述。我们使用了以下关键词:坏死性筋膜炎、病因机制、病理生理学、管理。</br> <b><br>结果:</b> 研究组由两名男性患者组成,他们在身体不同部位受到创伤后出现 NF。根据临床检查、实验室和影像学检查的结果做出了诊断,并开始了适当的治疗。尽管进行了治疗,但其中一名患者还是因进行性多器官功能衰竭而死亡。</br> <b><br>结论:</b> 尽管在诊断和治疗方面取得了进步,包括抗生素的普及,但坏死性筋膜炎仍然导致很高的死亡率。大多数病例的微生物学复杂性和非特异性症状给诊断和治疗过程带来了困难。在皮肤和皮下组织炎症的鉴别诊断中,每次都考虑到坏死性筋膜炎,尤其是基于创伤的坏死性筋膜炎,将有助于降低这种疾病的发病率和死亡率。
{"title":"Necrotizing fasciitis - two case reports and literature review.","authors":"Bartosz Molasy, Mateusz Frydrych","doi":"10.5604/01.3001.0053.9501","DOIUrl":"10.5604/01.3001.0053.9501","url":null,"abstract":"<p><p>&lt;b&gt;&lt;br&gt;Introduction:&lt;/b&gt; Necrotizing fasciitis (NF) is a rare, rapidly progressing infection of the skin and subcutaneous tissue. NF can lead to massive tissue necrosis, resulting in sepsis, septic shock and death. In this disease, it is important to quickly diagnose and implement appropriate treatment.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Aim:&lt;/b&gt; Analysis of the diagnostic and therapeutic process in two clinical cases and a review of the literature on the methods of diagnosis and treatment of necrotizing fasciitis.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Material and methods:&lt;/b&gt; The medical data of two patients hospitalized in the St Alexander Hospital in Kielce from December 2022 to June 2023 due to necrotizing fasciitis were analyzed. Also literature search across PubMed, Medline and Research Gate databases from 2000 up to 2023 was performed. We reviewed English literature according to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. The following keywords were used: necrotizing fasciitis, etiopathogenesis, pathophysiology, management.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Results:&lt;/b&gt; The research group consisted of two male patients with NF after trauma, in different parts of the body. Based on the clinical examination, the results of laboratory and imaging tests, a diagnosis was made and appropriate treatment was initiated. Despite the applied treatment, one patient died as a result of progressive multiple organ failure.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Conclusions:&lt;/b&gt; Despite advances in diagnosis and treatment, including universal access to antibiotics, necrotizing fasciitis still cause high mortality. The microbiological complexity of the majority of cases and non-specific symptoms make the diagnostic and therapeutic process difficult. Taking into account necrotizing fasciitis each time in the differential diagnosis of inflammation of the skin and subcutaneous tissue, especially based on trauma, will allow to reduce morbidity and mortality in this disease.&lt;/br&gt.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"96 0","pages":"103-108"},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
13 years of hand surgery without an anesthesiologist. An analysis of efficacy and safety of presurgical anesthesia as delivered by surgeons without the assistance of anesthesiologists. 没有麻醉师的手部手术 13 年。分析外科医生在没有麻醉师协助的情况下进行术前麻醉的有效性和安全性。
Pub Date : 2023-11-16 DOI: 10.5604/01.3001.0053.9843
Andrzej Żyluk

<b><br>Introduction:</b> The assistance of anaesthesiologist is considered an inseparable part of most surgical procedures, with the exception of a small proportion of minor procedures performed under local anaesthesia. In hand surgery, a vast majority of procedures, even those lasting several hours, can be carried out under regional (brachial plexus block) or local (infiltration) anaesthesia. These can be delivered by the surgeons themselves, allowing the surgeries to be carried out without the assistance of anesthesiologists.</br> <b><br>Aim:</b> The aim of this study was to analyze the efficacy and safety of presurgical anesthesia as delivered by surgeons without the assistance of anesthesiologists in the course of hand surgery procedures performed within the institution headed by the author of this article.</br> <b><br>Material and methods:</b> The analysis was based on the records of anesthesia protocols filled out by the surgeons who delivered the anesthesia and who operated on the patients. The variables considered included the efficacy of anesthesia and the anesthesia-related adverse effects and complications.</br> <b><br>Results:</b> Over a period of 13 years (2010-2022), a total of 24,703 surgeries were delivered; of these, 22,228 (91%) surgeries were carried out without anesthesiologists, with anesthesia being delivered by the surgeon him/herself. The efficacy of these procedures (local anasthesia and brachial plexus blocks combined) was 99%. A total of 631 (2.8%) anesthesia-related adverse reactions were recorded, most of them being transient, requiring immediate interventions and not leading to any serious sequelae. In only 17 cases (0.07%), adverse effects resulted in cancellation and rescheduling of the elective surgery.</br> <b><br>Conclusions:</b> Pre-surgical anesthesia as delivered prior to hand surgery procedures by the surgeons without the assistance of anesthesiologists is effective and safe while being associated with numerous benefits for patients, surgeons and the health care system's budget.</br>.

<b><br>引言:</b> 麻醉师的协助被认为是大多数外科手术不可分割的一部分,只有一小部分在局部麻醉下进行的小型手术除外。在手外科手术中,绝大多数手术,甚至是持续数小时的手术,都可以在区域(臂丛神经阻滞)或局部(浸润)麻醉下进行。这些麻醉可由外科医生自行实施,从而使手术无需麻醉师的协助即可进行。</br><b><br>材料和方法:</b>分析基于实施麻醉和为患者进行手术的外科医生填写的麻醉协议记录。考虑的变量包括麻醉效果以及与麻醉相关的不良反应和并发症。这些手术(局部麻醉和臂丛神经阻滞)的有效率为 99%。共记录了 631 例(2.8%)与麻醉相关的不良反应,其中大部分是一过性的,需要立即干预,不会导致任何严重的后遗症。仅有 17 例(0.07%)不良反应导致了择期手术的取消和重新安排。
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引用次数: 0
Peritoneal and Systemic Interleukin-10 as Early Biomarkers for Colorectal Anastomotic Leakage Following Surgery in Colorectal Cancer Patients: A Systematic Review and Meta-Analysis. 腹膜和全身白细胞介素-10作为大肠癌患者术后大肠吻合口渗漏的早期生物标记物:系统回顾与元分析》。
Pub Date : 2023-11-16 DOI: 10.5604/01.3001.0053.9836
Lucía Villegas-Coronado, Karla Villegas-Coronado, Diana Villegas Coronado

<b><br>Introduction:</b> Despite advancements in diagnostic methods, the early detection of colorectal anastomotic leakage (CAL) continues to pose challenges. The identification of reliable markers is crucial to reduce patient morbidity and mortality. Cytokines present in drain fluid and systemic cytokine levels have shown promise as predictive markers for CAL; however, additional high-quality evidence is warranted to enhance the reliability and validity of the findings in this field.</br> <b><br>Aim:</b> This systematic review and meta-analysis aimed to assess the significance of peritoneal and serum/plasma interleukin-10 (IL-10) levels in the early detection of CAL in patients undergoing colorectal surgery for colorectal cancer.</br> <b><br>Methods:</b> A comprehensive literature search was conducted in PubMed, Scopus, and Web of Science databases, covering studies published until July 2023. The search aimed to identify relevant studies investigating the levels of plasma/serum and peritoneal IL-10 (or both) in colorectal cancer patients undergoing colorectal surgery, specifically focusing on the presence of CAL. Data on the mean and standard deviation of IL-10 levels in both CAL and non-CAL patients were extracted from the selected studies. Mean differences in IL-10 levels were analyzed for each postoperative day (POD) using the OpenMeta [analyst] software.</br> <b><br>Results:</b> 11 articles were selected for inclusion in this systematic review. Among them, nine articles reported data on peritoneal IL-10 levels, while four articles focused on circulating IL-10 levels. The statistical analysis included four eligible articles that assessed peritoneal IL-10 levels, and the results indicated no significant increase in CAL patients compared to non-CAL patients on any postoperative day (POD). Meta-analysis for circulating IL-10 levels was not feasible.</br> <b><br>Conclusions:</b> Up to now, peritoneal and systemic IL-10 levels cannot be considered as early markers for CAL after colorectal surgery in colorectal cancer patients. More high-quality studies are needed to establish the potential of IL-10 as a reliable marker for detecting anastomotic leakage after colorectal surgery.</br>.

<b><br>引言:</b> 尽管诊断方法不断进步,但结肠直肠吻合口漏(CAL)的早期检测仍面临挑战。确定可靠的标记物对降低患者发病率和死亡率至关重要。引流液中的细胞因子和全身细胞因子水平已显示出作为 CAL 预测标记物的前景;然而,还需要更多高质量的证据来提高该领域研究结果的可靠性和有效性。</br><b><br>方法:</b>在PubMed、Scopus和Web of Science数据库中进行了全面的文献检索,涵盖了2023年7月之前发表的研究。该检索旨在确定调查接受结直肠手术的结直肠癌患者血浆/血清和腹膜IL-10(或两者)水平的相关研究,特别关注是否存在CAL。从所选研究中提取了 CAL 和非 CAL 患者 IL-10 水平的平均值和标准偏差数据。使用 OpenMeta [分析师] 软件分析了每个术后日 (POD) IL-10 水平的平均差异。其中,9篇文章报告了腹膜IL-10水平的数据,4篇文章关注循环IL-10水平。统计分析纳入了四篇符合条件的评估腹膜IL-10水平的文章,结果显示,与非CAL患者相比,CAL患者在术后任何一天(POD)的腹膜IL-10水平都没有显著增加。循环 IL-10 水平的 Meta 分析不可行。需要进行更多高质量的研究,以确定IL-10作为检测结直肠手术后吻合口漏的可靠标记物的潜力。
{"title":"Peritoneal and Systemic Interleukin-10 as Early Biomarkers for Colorectal Anastomotic Leakage Following Surgery in Colorectal Cancer Patients: A Systematic Review and Meta-Analysis.","authors":"Lucía Villegas-Coronado, Karla Villegas-Coronado, Diana Villegas Coronado","doi":"10.5604/01.3001.0053.9836","DOIUrl":"10.5604/01.3001.0053.9836","url":null,"abstract":"<p><p>&lt;b&gt;&lt;br&gt;Introduction:&lt;/b&gt; Despite advancements in diagnostic methods, the early detection of colorectal anastomotic leakage (CAL) continues to pose challenges. The identification of reliable markers is crucial to reduce patient morbidity and mortality. Cytokines present in drain fluid and systemic cytokine levels have shown promise as predictive markers for CAL; however, additional high-quality evidence is warranted to enhance the reliability and validity of the findings in this field.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Aim:&lt;/b&gt; This systematic review and meta-analysis aimed to assess the significance of peritoneal and serum/plasma interleukin-10 (IL-10) levels in the early detection of CAL in patients undergoing colorectal surgery for colorectal cancer.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Methods:&lt;/b&gt; A comprehensive literature search was conducted in PubMed, Scopus, and Web of Science databases, covering studies published until July 2023. The search aimed to identify relevant studies investigating the levels of plasma/serum and peritoneal IL-10 (or both) in colorectal cancer patients undergoing colorectal surgery, specifically focusing on the presence of CAL. Data on the mean and standard deviation of IL-10 levels in both CAL and non-CAL patients were extracted from the selected studies. Mean differences in IL-10 levels were analyzed for each postoperative day (POD) using the OpenMeta [analyst] software.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Results:&lt;/b&gt; 11 articles were selected for inclusion in this systematic review. Among them, nine articles reported data on peritoneal IL-10 levels, while four articles focused on circulating IL-10 levels. The statistical analysis included four eligible articles that assessed peritoneal IL-10 levels, and the results indicated no significant increase in CAL patients compared to non-CAL patients on any postoperative day (POD). Meta-analysis for circulating IL-10 levels was not feasible.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Conclusions:&lt;/b&gt; Up to now, peritoneal and systemic IL-10 levels cannot be considered as early markers for CAL after colorectal surgery in colorectal cancer patients. More high-quality studies are needed to establish the potential of IL-10 as a reliable marker for detecting anastomotic leakage after colorectal surgery.&lt;/br&gt.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"96 0","pages":"135-142"},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Surgery in Chronic Pancreatitis. 手术在慢性胰腺炎中的作用。
Pub Date : 2023-11-16 DOI: 10.5604/01.3001.0053.9841
Miloš Kňazovický, Veronika Roškovičová, Tomáš Gajdzik, Tomáš Hildebrand, Jana Kaťuchová, Jozef Radoňák

Chronic pancreatitis is an inflammatory disease characterized by the progressive replacement of the functional pancreatic parenchyma with fibrotic tissue. This leads to exocrine and endocrine insufficiency. A typical clinical feature is recurrent, severe upper abdominal pain, which negatively affects the patient's quality of life. Conservative treatment as the method of first choice does not prevent irreversible changes in the pancreatic tissue. While endoscopic drainage can have some benefits in the early stages of the disease, it is generally unsuccessful in the long term. Based on recent studies, surgical intervention appears to be the most suitable treatment option for improving the patient's quality of life. It currently includes a wide range of effective, proven drainage and resection procedures. Advances in surgical techniques and postsurgical intensive care have increased the frequency of pancreatic surgeries, while improvements in diagnostic methods have increased the number of patients who meet the indications for such surgery, including elderly and chronically ill patients. However, despite mortality rates decreasing, high morbidity rates remain a problem. Currently, in patients with an inflammatory mass in the head of the pancreas, pyloric and duodenal-preserving resection offers the best results. Different variants of these techniques appear to produce similar results. Various techniques have shown similar outcomes in terms of mortality, morbidity, pain relief, life expectancy and improved quality of life. The optimal timing of surgery has been addressed by several studies and most surgeons now favor early surgical intervention in order to prevent extensive destruction of pancreatic tissue.

慢性胰腺炎是一种炎症性疾病,其特点是功能性胰腺实质逐渐被纤维组织取代。这会导致外分泌和内分泌功能不全。典型的临床特征是反复发作的剧烈上腹部疼痛,对患者的生活质量造成负面影响。作为首选方法的保守治疗并不能防止胰腺组织发生不可逆的变化。虽然内镜引流术在疾病的早期阶段有一定的疗效,但从长远来看一般是不成功的。根据最近的研究,手术干预似乎是改善患者生活质量的最合适治疗方案。目前,它包括一系列有效、成熟的引流和切除手术。手术技术和术后重症监护的进步增加了胰腺手术的频率,同时诊断方法的改进也增加了符合此类手术适应症的患者人数,包括老年患者和慢性病患者。然而,尽管死亡率有所下降,但高发病率仍是一个问题。目前,对于胰腺头部有炎症肿块的患者,保留幽门和十二指肠的切除术效果最好。这些技术的不同变体似乎产生了相似的效果。在死亡率、发病率、疼痛缓解、预期寿命和生活质量改善方面,各种技术都显示出相似的效果。多项研究已经探讨了手术的最佳时机,目前大多数外科医生都倾向于早期手术干预,以防止胰腺组织遭到广泛破坏。
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引用次数: 0
Evaluation of outcomes of lower eyelid entropion and ectropion surgical repair. 下眼睑内翻和外翻手术修复效果评估。
Pub Date : 2023-10-17 DOI: 10.5604/01.3001.0053.9352
Ewa Woźniak-Roszkowska, Aleksandra Iljin, Bartlomiej Noszczyk, Bogusław Antoszewski

<b><br>Introduction:</b> The imbalance of external and internal forces acting on the lower eyelid can result in entropion and ectropion, both of which cause ocular irritation and loss of proper eye protection. Potential complications of untreated cases include recurrent inflammation of the conjunctiva and cornea, conjunctival neovascularization, corneal abrasion or perforation, and ultimately even loss of vision. Although various surgical techniques are used to address this problem, their long-term outcome and effectiveness are still under discussion. </br> <b><br>Aim:</b> To evaluate outcomes of surgery for entropion and ectropion, including a modified Wheeler's method for entropion correction.</br> <b><br>Methods:</b> A non-comparative study (prospective and retrospective groups) included 100 patients operated on in two university hospitals' plastic surgery departments for lower eyelid entropion or ectropion, following formal ethics approval. The prospective group included 50 patients assessed preoperatively and at 3 and 12 months postoperatively. The retrospective group was comprised of 50 patients (2012-2018), whose preoperative documentation and clinical examinations were analyzed. The main outcome measures were change between pre- and postoperative patient-reported symptoms (VAS scale), ectropion/entropion grading scale (EGS/EnGS), quality of life (WHOQOL-BREF), and occurrence of complications.</br> <b><br>Results:</b> The differences in the severity of all symptoms before and after surgery evaluated with the VAS scale were statistically significant in both groups (p <0.05). We observed 6 recurrences (12%) in the prospective group and 9 (18%) in the retrospective group, with minor complications. Very good functional and esthetic postoperative results were confirmed in 70% (79) of the whole group and in 13 patients (81.3%) treated with the modified Wheeler's method. In the prospective group, the Mann- Whitney U test for dependent variables revealed significant improvement in the somatic, psychological, and environmental domains, with no significant change in the social relationships domain.</br> <b><br>Conclusions:</b> The results following entropion/ectropion surgery prove the effectiveness of the methods used. Complementing them with the modified Wheeler's method brought an increase in the number of very good outcomes. Surgery of lower eyelid malposition contributed to reduced symptoms and improved quality of life. The rates of postoperative sequelae were low.</br>.

<b><br>引言:</b> 作用于下眼睑的内外力不平衡会导致内翻和外翻,这两种情况都会对眼部造成刺激,使眼睛失去适当的保护。未经治疗的病例可能出现的并发症包括结膜和角膜反复发炎、结膜新生血管、角膜擦伤或穿孔,最终甚至导致视力丧失。</br> <b><br>Aim:</b> To evaluate outcomes of surgery for entropion and ectropion, including a modified Wheeler's method for entropion correction.前瞻组包括 50 名接受术前评估以及术后 3 个月和 12 个月评估的患者。回顾组包括50名患者(2012-2018年),对其术前文件和临床检查进行了分析。主要结果指标为术前和术后患者报告症状(VAS量表)、外翻/外翻分级量表(EGS/EnGS)、生活质量(WHOQOL-BREF)和并发症发生率的变化。我们观察到,前瞻性手术组有 6 例复发(12%),回顾性手术组有 9 例(18%),并发症较轻。全组 70% 的患者(79 人)和采用改良 Wheeler 方法治疗的 13 名患者(81.3%)均证实术后功能和美观效果非常好。在前瞻性组中,对因变量进行的曼-惠特尼 U 检验显示,躯体、心理和环境领域均有显著改善,而社会关系领域则无明显变化。使用改良的惠勒方法对这些方法进行补充后,取得非常好效果的人数有所增加。下眼睑位置不正手术有助于减轻症状,提高生活质量。术后后遗症的发生率很低。
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引用次数: 0
Postoperative Distal Enteral Tube Refeeding in Stoma Patients: A Comparative Analysis of Clinical Outcomes. 造口患者术后远端肠管再喂养:临床结果对比分析。
Pub Date : 2023-10-17 DOI: 10.5604/01.3001.0053.9351
Jignesh Gandhi, Aadrika Kashyap, Pravin Shinde

<b><br>Introduction:</b> Stoma surgery, which involves creating a diversion of the small intestine through an abdominal wall opening, poses challenges in managing fluid and electrolyte imbalances. Patients with high proximal stoma often rely on costly and risky parenteral nutrition (PN). Distal enteral tube feeding, a method of delivering nutrition to the small intestine, is intended to improve clinical outcomes and reduce complications. This study presents a comparative analysis of clinical outcomes between postoperative distal enteral tube refeeding and traditional enteral and PN approaches in stoma patients with distal mucous fistula.</br> <b><br>Aim:</b> To evaluate the effectiveness of distal enteral tube refeeding in improving postoperative outcomes after stoma surgery and to examine the impact of distal enteral tube refeeding on total hospitalization stay, ICU length of stay, TPN duration, and time to closure of the stoma.</br> <b><br>Material and methods:</b> The study is a retrospective, single-center trial involving 84 patients who had undergone stoma surgery. The patients were divided into two groups: those receiving postoperative distal enteral tube refeeding (n = 42) and the control group (n = 42), with standard mucous fistula creation. The data was collected retrospectively from January 2012 to January 2022 and the statistical analysis was performed using descriptive statistics, the chi-square test, and the t-test.</br> <b><br>Results:</b> The results of our study show that the patients who had undergone postoperative distal enteral tube refeeding had a significantly shorter total hospitalization stay (p = 0.0002), a significantly shorter ICU length of stay (p = 0.0006), a significantly shorter TPN duration (p= 0.0004), and a significantly faster time to closure (p = 0.0002).</br>.

<b><br>引言:</b> 造口手术涉及通过腹壁开口将小肠改道,给液体和电解质失衡的管理带来了挑战。高位造口患者通常需要依赖昂贵且高风险的肠外营养(PN)。远端肠管喂养是一种向小肠输送营养的方法,旨在改善临床效果并减少并发症。本研究对患有远端粘液瘘的造口患者术后远端肠管再喂养与传统肠内和肠外营养方法的临床疗效进行了比较分析。</br><b><br>材料和方法:</b>该研究是一项回顾性单中心试验,涉及 84 名接受造口手术的患者。患者分为两组:术后接受远端肠管再喂养组(42 人)和对照组(42 人),对照组采用标准粘液造瘘术。数据收集时间为 2012 年 1 月至 2022 年 1 月,采用描述性统计、卡方检验和 t 检验进行统计分析。
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引用次数: 0
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Polski przeglad chirurgiczny
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