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Trends in the Treatment of Hypertension within Managed Care Organizations: A National Survey of HMO Pharmacy Directors 管理式医疗机构内高血压治疗的趋势:对HMO药房主任的全国调查
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.1997.3.3.317
Eric Bobal
OBJECTIVE: To estimate the prevalence of changes to the initial treatment regimen of hypertensive patients in a managed care setting and to identify the factors having the most impact on the cost of treatment. Utilization patterns specifically related to angiotensin converting enzyme inhibitors (ACEls) and calcium channel blockers (CCBs) were looked at because of their particular cost impact. Secondary goals were to assess the types of changes made to therapy and to estimate the ACEI/CCB concomitancy rates (the number of patients receiving both medications at the same time) among these hypertensive patients, and the cost impact of these. DESIGN: In May 1995, a survey regarding the treatment of hypertension in managed care was faxed to a random sampling of pharmacy directors of 250 large (greater than 40,000 enrollees) managed care plans throughout the United States. A total of 29 pharmacy directors completed and returned the survey; all responses were included in the study analysis. The 29 plans represent...
目的:评估管理式医疗环境中高血压患者初始治疗方案改变的流行程度,并确定对治疗成本影响最大的因素。血管紧张素转换酶抑制剂(ACEls)和钙通道阻滞剂(CCBs)的使用模式由于其特殊的成本影响而受到关注。次要目标是评估治疗变化的类型,估计这些高血压患者的ACEI/CCB伴随率(同时接受两种药物治疗的患者数量),以及这些药物的成本影响。设计:1995年5月,一项关于管理式医疗中高血压治疗的调查被传真给全美250个大型管理式医疗计划(超过40,000名参保者)的药房主任随机抽样。共有29名药房总监完成并返回调查;所有的回答都被纳入研究分析。这29个计划代表了……
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引用次数: 1
The Cost-Effectiveness Impact of a Preferred Agent HMG-CoA Reductase Inhibitor Policy in a Managed Care Population 在管理护理人群中首选HMG-CoA还原酶抑制剂政策的成本-效果影响
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.1997.3.5.548
A. Petitta
OBJECTIVE: The purpose of this study was to analyze the economic and health outcomes of implementing a preferred agent (HMG-CoA) reductase inhibitor policy in a managed care population. DESIGN: A Markov model with three states was constructed: 1) alive with no cardiac or coronary heart disease (CHD), 2) alive with CHD; and, 3) dead. In the model patients can move from one state to another as a function of CHD risk factors and expected changes in the lipid levels secondary to therapy. Event rates for CHD-related hospitalizations are also predicted. Health care costs included hospitalization costs for CHD events and HMG-CoA drug costs. Risk factor data were collected on a random sample of 150 patients of the 3,500 managed care patients receiving HMG-CoA therapy. Outcomes were modeled until age 80. Results were generated for a baseline of one year before and six months after implementation of the policy. SETTING: Group practice managed care organization. PATIENTS: Patients receiving HMG-CoA reductase inhibit...
目的:本研究的目的是分析在管理护理人群中实施首选药物(HMG-CoA)还原酶抑制剂政策的经济和健康结果。设计:构建具有三种状态的马尔可夫模型:1)活着,无心脏或冠心病(CHD); 2)活着,有冠心病;然后,死了。在模型中,患者可以从一种状态转移到另一种状态,这是冠心病危险因素和治疗后血脂水平预期变化的功能。还预测了冠心病相关住院的事件发生率。医疗费用包括冠心病事件的住院费用和HMG-CoA药物费用。从3500名接受HMG-CoA治疗的管理护理患者中随机抽取150名患者进行风险因素数据收集。结果被建模到80岁。结果以政策实施前一年和实施后六个月为基准。单位:团体实践管理式医疗机构。患者:患者接受HMG-CoA还原酶抑制…
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引用次数: 0
Do We Measure Up in Reducing Morbidity and Mortality 我们在降低发病率和死亡率方面达标了吗
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.1997.3.6.651
Taeho Oh
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引用次数: 0
Going to the Source: A Guide to Using Surveys in Health Care Research 溯源:在卫生保健研究中使用调查的指南
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.1999.5.2.150
K. Fairman
CONCLUSION: The following principles should guide project planning and questionnaire construction: 1) enlist the respondent's interest and trust; 2) maintain trust by keeping respondent burden to a minimum; 3) provide an attractive product; 4) avoid confusing, threatening, or biased questions; and 5) ensure that the questionnaire is consistent with planned data analyses. Several additional procedures enhance the usefulness of survey results: pretesting,
结论:项目规划和问卷构建应遵循以下原则:1)引起被调查者的兴趣和信任;2)保持信任,将被调查者的负担降至最低;3)提供有吸引力的产品;4)避免混淆、威胁或有偏见的问题;5)确保问卷与计划的数据分析相一致。几个额外的程序提高了调查结果的有效性:预测试;
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引用次数: 1
Depression in Managed Care: Costs of Selective Serotonin Reuptake Inhibitors 管理护理中的抑郁症:选择性血清素再摄取抑制剂的成本
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.2001.7.2.142
B. Mcfarland
OBJECTIVE: To review data on the comparative costs of antidepressants. DESIGN: Review of data from articles identified in a Medline search, meeting presentations, and independent market research that are relevant to the costs associated with treating depression. Studies were included if they compared depression treatment costs with tricyclic antidepressants to those with one of the leading selective serotonin reuptake inhibitors (SSRIs) or if they compared treatment costs among the leading SSRIs. Data were extracted on drug acquisition costs, concomitant medications, dose titration, multitablet/multi-capsule therapy, duration of therapy, and overall treatment costs. RESULTS: SSRIs may be more costeffective than tricyclic antidepressants because they are associated with lower health care utilization. Assessment of economic outcomes with SSRI therapy can be based on identified cost drivers, including dose titration and the need for multi-tablet therapy. Among the SSRIs, the uses of nonpharmaceutical health ...
目的:回顾抗抑郁药的比较成本数据。设计:回顾Medline检索、会议报告和独立市场研究中与治疗抑郁症相关费用相关的文章的数据。如果研究比较了三环类抗抑郁药和一种主要的选择性血清素再摄取抑制剂(SSRIs)的治疗费用,或者比较了主要的SSRIs的治疗费用,那么这些研究就被纳入其中。提取有关药物获取成本、伴随用药、剂量滴定、多片/多胶囊治疗、治疗持续时间和总体治疗成本的数据。结果:SSRIs可能比三环抗抑郁药更具成本效益,因为它们与较低的医疗保健使用率相关。对SSRI治疗的经济效果的评估可以基于确定的成本驱动因素,包括剂量滴定和多片治疗的需要。在ssri类药物中,非药物类保健药物的使用…
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引用次数: 0
Driving Market Share in an Integrated Health System without Therapeutic Interchange 在没有治疗交换的综合卫生系统中推动市场份额
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.2001.7.4.283
J. Fischer, R. M. Mowers, David J. Ormerod, Ellen S. Burriss
OBJECTIVE: Shift selective serotonin reuptake inhibitor (SSRI) market share in a large integrated health system to a more cost-effective alternative without the need for therapeutic interchange. SETTING: University of California Davis Medical Group (UCDMG). PRACTICE INNOVATION: Integrate the managed care team into the routine operation of the medical group clinics. Influence prescribing patterns by a program of continuous physician education, giving the messages that (1) citalopram was the most costeffective SSRI; (2) fluoxetine is the least cost-effective, especially at doses above 20 mg; and (3) that citalopram should be considered as initial therapy for depression and for patients not achieving optimal therapy on their current SSRI. OUTCOMES MEASURES: Change in market share for SSRIs: prescriptions for citalopram and fluoxetine were monitored for a year after the physician education program began. RESULTS: Market share for citalopram increased dramatically. Starting below the reported national usage, t...
目的:将选择性5 -羟色胺再摄取抑制剂(SSRI)在大型综合医疗系统中的市场份额转移到更具成本效益的替代方案,而无需治疗交换。单位:加州大学戴维斯分校医疗集团(UCDMG)。实践创新:将管理式医疗团队整合到医疗集团诊所的日常运作中。通过医师持续教育项目影响处方模式,给予以下信息:(1)西酞普兰是最具成本效益的SSRI;(2)氟西汀最不划算,尤其是在剂量大于20mg时;(3)西酞普兰应被视为抑郁症的初始治疗,对于目前SSRI治疗效果不佳的患者。结果测量:SSRIs市场份额的变化:在医师教育项目开始后,对西酞普兰和氟西汀处方进行了一年的监测。结果:西酞普兰的市场份额急剧增加。从报道的全国用法开始,t…
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引用次数: 0
Collaborating with Community Pharmacists to Improve the Quality of Diabetes Care in an IPA-model HMO 与社区药师合作提高ipa模式HMO糖尿病护理质量
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.2001.7.4.292
D. Nau, Joshua D. Blevins, Stephen Neal
OBJECTIVE: To assess the ability of community pharmacists to identify managed care patients with diabetes who are not achieving therapeutic goals. SETTING: A network of independent community pharmacists in West Virginia and southeastern Ohio in collaboration with The Health Plan of the Upper Ohio Valley. METHODS: Pharmacists conducted assessments of patients’ glycemic control (HbA1c ), blood pressure (BP), lipid levels (total cholesterol, low-den sity lipoprotein [LDL], high-density lipoprotein [HDL], triglycerides), and body mass index (BMI). The therapeutic goals were: HbA 1c less than 7%, BP lower than 130/85 mmHg, total cholesterol under 200 mg/dl, LDL less than 100mg/dl, HDL lower than 45 mg/dl, triglycerides under 200 mg/dl, and BMI lower than 30. These indices were measured during scheduled appointments in the pharmacy by pharmacists who had completed a certificate program in diabetes care. Reports on each patient’s status, along with recommendations, were sent to the patient’s physician. RESULTS: Fifty-four persons were enrolled in the pharmacist program and complete clinical data were obtained for 47 patients. The following percentages of patients were identified as not achieving the therapeutic goal for a particular measure: HbA1c: 63.9%, BP: 56.3%, total cholesterol: 38.3%, LDL: 69.8%, HDL: 76.5%, triglycerides: 57.4%, BMI: 61.9%. Patients who were not reaching the therapeutic target were referred to their physicians for additional evaluation. CONCLUSION: Pharmacists can identify a substantial number of persons with diabetes who are not achieving the goals for HbA 1c , blood pressure, lipids, and weight. This approach can facilitate the continuous assessment and improvement of care for managed care enrollees with diabetes.
目的:评估社区药师识别管理护理未达到治疗目标的糖尿病患者的能力。地点:一个由西弗吉尼亚州和俄亥俄州东南部独立社区药剂师组成的网络,与上俄亥俄河谷的健康计划合作。方法:药师对患者的血糖控制(HbA1c)、血压(BP)、脂质水平(总胆固醇、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、甘油三酯)和体重指数(BMI)进行评估。治疗目标为:HbA 1c低于7%,血压低于130/85 mmHg,总胆固醇低于200 mg/dl, LDL低于100mg/dl, HDL低于45 mg/dl,甘油三酯低于200 mg/dl, BMI低于30。这些指标是由完成糖尿病护理证书课程的药剂师在药房预约时测量的。每个病人的状况报告以及建议都被发送给病人的医生。结果:54人入选药师项目,47例患者获得完整的临床资料。以下百分比的患者被确定为未达到特定测量的治疗目标:HbA1c: 63.9%, BP: 56.3%,总胆固醇:38.3%,LDL: 69.8%, HDL: 76.5%,甘油三酯:57.4%,BMI: 61.9%。未达到治疗目标的患者被转介给他们的医生进行额外的评估。结论:药剂师可以识别出大量未达到HbA 1c、血压、血脂和体重目标的糖尿病患者。这种方法可以促进持续的评估和护理的改善管理保健登记糖尿病。
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引用次数: 2
A Model for Comparing Unnecessary Costs Associated with Various Prescription Fill-Quantity Policies: Illustration Using VA Data 一个比较不同处方填充量政策的不必要成本的模型:使用VA数据的说明
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.2001.7.5.386
S. Walton, B. Arondekar, N. Johnson, G. Schumock
OBJECTIVE: To describe a model for analyzing the unnecessary costs associated with outpatient prescription fill quantities and to apply the model to prescription data from the Veterans Administration’s Chicago Health Care System (VACHCS) to examine costs under various scenarios. DESIGN: The model developed here included the cost of drugs, quantity of drug wasted, and the cost to fill the prescription, and is used to determine and compare the total unnecessary costs (TUC) of different prescription fill quantities. The model was applied to the VACHCS outpatient prescription records for two formulary hydroxymethyl glutaryl coenzyme A (HMGCoA) reductase-inhibitor drugs to determine TUC for 30- and 90-day fills. Sensitivity analysis was used to analyze changes in the TUC over a range of possible values for each variable in the model. RESULTS: A total of 16,990 prescriptions met the study inclusion criteria, of which 21.4% were for a 30-day supply and 78.6% for a 90-day supply. For 30-day and 90-day prescriptions, the average prescription cost per day was $0.56 and $0.54, respectively; quantity wasted was 1.06 days and 5.33 days; and TUC per prescription were $5.62 and $3.17. Sensitivity analysis demonstrated that the 90day policy maintained lower TUC for most scenarios with the exception of very high drug costs. CONCLUSION: Prescription benefit managers will find this model informative for determining policies for prescription fill quantities.
目的:描述一个分析与门诊处方填充量相关的不必要成本的模型,并将该模型应用于退伍军人管理局芝加哥医疗保健系统(VACHCS)的处方数据,以检查各种情况下的成本。设计:本文建立的模型包括药品成本、浪费药品数量和处方填充成本,用于确定和比较不同处方填充数量的总不必要成本(TUC)。将该模型应用于两种羟甲基戊二酰辅酶A (HMGCoA)还原酶抑制剂处方的VACHCS门诊处方记录,以确定30天和90天的TUC。敏感性分析用于分析TUC在模型中每个变量的可能值范围内的变化。结果:共有16990张处方符合研究纳入标准,其中30天处方占21.4%,90天处方占78.6%。对于30天和90天的处方,平均处方费用分别为每天0.56美元和0.54美元;浪费量分别为1.06天和5.33天;每张处方分别为5.62美元和3.17美元。敏感性分析表明,除了药费非常高的情况外,90天政策在大多数情况下保持较低的TUC。结论:处方福利管理人员将发现该模型为确定处方填充数量的政策提供了信息。
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引用次数: 4
New Challenges to Old Standards in the Treatment of Rhinitis 鼻炎治疗对旧标准的新挑战
Pub Date : 2015-09-15 DOI: 10.18553/JMCP.2001.7.S2.1
W. Berge, O. Shoheiber, D. Giaquinta, E. Cannon, G. Ledgerwood
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引用次数: 0
Evaluating Utilization Patterns 评估利用模式
Pub Date : 2015-09-15 DOI: 10.18553/jmcp.2001.7.s2.7
W. Berger, O. Shoheiber, D. Giaquinta, E. Cannon, G. Ledgerwood
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引用次数: 0
期刊
Journal of Managed Care Pharmacy
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