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Primary Breast Carcinoid With Metastasis and Ectopic Acth Secretion: A Diagnostic Dilemma 原发性类乳腺癌伴转移和异位Acth分泌:诊断困境
Pub Date : 2010-05-01 DOI: 10.1097/TEN.0B013E3181DEE646
E. Baessa
Abstract: Carcinoid tumors most frequently develop in the gastrointestinal tract but have been described in many organs of the body. Primary neuroendocrine carcinoma of the breast is rare-only 31 cases have been reported in literature. Immunohistochemical examination showing expression of chromogranin and/or synaptophysin confirms evidence of neuroendocrine differentiation. In primary neuroendocrine carcinoma of the breast, more than 50% of the cell population shows neuroendocrine differentiation. Foci of neuroendocrine differentiation usually can be seen in breast carcinoma and are reported to be present in about 2% to 5% of breast cancer cases. Carcinoid tumor metastatic to the liver from the breast is very unusual. We report a case in which the patient underwent breast lumpectomy with axillary dissection. The tumor initially was diagnosed as an infiltrative lobular carcinoma with axillary lymph node metastasis. Re-examination of the breast tumor histopathology, however, proved it to be a primary carcinoid tumor.
摘要:类癌肿瘤最常发生在胃肠道,但在身体的许多器官中都有报道。原发性乳腺神经内分泌癌是罕见的,文献中仅报道了31例。免疫组化检查显示嗜铬粒蛋白和/或突触素的表达证实了神经内分泌分化的证据。在乳腺原发性神经内分泌癌中,超过50%的细胞群表现为神经内分泌分化。神经内分泌分化病灶通常见于乳腺癌,据报道约有2%至5%的乳腺癌病例存在神经内分泌分化灶。类癌从乳房转移到肝脏是非常罕见的。我们报告一个病例,病人接受乳房肿瘤切除术与腋窝清扫。肿瘤最初被诊断为浸润性小叶癌伴腋窝淋巴结转移。复查乳腺肿瘤组织病理学,证实为原发性类癌。
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引用次数: 1
Incidental Thyroid Cancer in Head and Neck Squamous Cell Carcinoma: An Individualized Approach 头颈部鳞状细胞癌偶发甲状腺癌:个体化方法
Pub Date : 2010-05-01 DOI: 10.1097/TEN.0B013E3181DFFED2
J. Dora, Walter Escouto Machado, G. Geib, K. Pêgas, J. Guimarães, Alceu Migliavaca, A. Maia
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引用次数: 1
Childhood Combined Pituitary Hormone Deficiency: A Five-Year Retrospective Study 儿童期合并垂体激素缺乏症:一项五年回顾性研究
Pub Date : 2010-05-01 DOI: 10.1097/TEN.0B013E3181DFE163
C. Zou, Xian Chen, L. Liang, Zhengyan Zhao
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引用次数: 2
Bilateral Giant Myelolipoma of Adrenal Glands: A Case Report and Review of the Literature 双侧肾上腺巨大骨髓瘤1例报告及文献复习
Pub Date : 2010-04-01 DOI: 10.1097/TEN.0B013E3181FC469B
Petra Šulentić, B. Spajić, Igor Grubisic, M. Spajić, M. Vrkljan
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引用次数: 2
Bilateral Adrenal Haemorrhage and Evans Syndrome as the Initial Presentation of Antiphospholipid Syndrome From Systemic Lupus Erythematosus 双侧肾上腺出血和埃文斯综合征是系统性红斑狼疮抗磷脂综合征的初始表现
Pub Date : 2010-03-01 DOI: 10.1097/TEN.0B013E3181D54A9D
W. H. Yong, Y. Kon, C. Rajasoorya, Park Nam Julian Goh, H. Howe
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引用次数: 0
Hyperandrogenemia in a Postmenopausal Female That is Suppressed With Metformin Can Avoid Unnecessary Surgery 二甲双胍抑制绝经后女性高雄激素血症可避免不必要的手术
Pub Date : 2010-03-01 DOI: 10.1097/TEN.0B013E3181D4AB95
D. Bell, Patrick J. OʼNeill
{"title":"Hyperandrogenemia in a Postmenopausal Female That is Suppressed With Metformin Can Avoid Unnecessary Surgery","authors":"D. Bell, Patrick J. OʼNeill","doi":"10.1097/TEN.0B013E3181D4AB95","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181D4AB95","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"6 1","pages":"83-85"},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76039668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Cases of Precocious Puberty With Hypothyroidism: A Case Series With Review of Literature 性早熟伴甲状腺功能减退罕见病例分析并文献复习
Pub Date : 2010-03-01 DOI: 10.1097/TEN.0B013E3181C8CF50
S. Acharya, B. Mathew, P. Menon, T. Bandgar, N. Shah
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引用次数: 2
Surgical management of extra-adrenal abdominal paragangliomas: Report of three cases and review of the literature 肾上腺外腹部副神经节瘤的手术治疗:三例报告及文献复习
Pub Date : 2010-03-01 DOI: 10.1097/TEN.0B013E3181D4BF9A
A. Polistena, G. Cavallaro, D. Cotesta, L. Petramala, C. Letizia, U. Basile, S. Filetti, A. Cavallaro, G. Toma
Introduction: The incidence of pheochromocytomas is about 1–2/100000 in the adult population. Nearly 10% have an extra-adrenal location or multiple locations and are defined as paragangliomas. They might be catecholaminesecreting as ordinary pheochromocytomas or clinically asymptomatic with compression symptoms. Patients and Methods: Three cases of abdominal paraganglioma with different clinical onset are reported. Discussion: Incidentally diagnosed asymptomatic retroperitoneal tumors with secondary hypertension suggest paraganglioma. Increased levels of catecholamine and extra-adrenal lesions identified at CT or MR imaging with positive MIBG scintigraphy support the diagnosis. Optimal care requires a multidisciplinary approach, accurate preoperative exact localization and adequate preoperative medical treatment to reduce perioperative cardiovascular complications.
成人嗜铬细胞瘤的发病率约为1-2/100000。近10%的副神经节瘤位于肾上腺外或多处,被定义为副神经节瘤。它们可能像普通嗜铬细胞瘤一样分泌儿茶酚胺或临床无症状伴压迫症状。患者与方法:报告3例临床表现不同的腹部副神经节瘤。讨论:偶然诊断的无症状腹膜后肿瘤伴继发性高血压提示副神经节瘤。儿茶酚胺水平升高和肾上腺外病变在CT或MR成像中发现的MIBG阳性支持诊断。最佳护理需要多学科的方法,准确的术前精确定位和充分的术前治疗,以减少围手术期心血管并发症。
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引用次数: 1
Pituitary Apoplexy Manifested as Subarachnoid Hemorrhage Accompanied by Primary Hypothyroidism: A Case Report 垂体中风表现为蛛网膜下腔出血伴原发性甲状腺功能减退1例
Pub Date : 2010-03-01 DOI: 10.1097/TEN.0B013E3181D59778
F. Zheng, Weina Lu, Hong Li, Xue-hong Dong
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引用次数: 3
Solitary Iliac Bone Metastasis of a Follicular Thyroid Carcinoma Causing T3-Toxicosis 滤泡性甲状腺癌单独髂骨转移致t3中毒
Pub Date : 2010-03-01 DOI: 10.1097/TEN.0B013E3181D4AB16
G. F. Taboada, Erika A. Caramez, D. A. T. D. Souza, R. A. Pinheiro, M. Vaisman
{"title":"Solitary Iliac Bone Metastasis of a Follicular Thyroid Carcinoma Causing T3-Toxicosis","authors":"G. F. Taboada, Erika A. Caramez, D. A. T. D. Souza, R. A. Pinheiro, M. Vaisman","doi":"10.1097/TEN.0B013E3181D4AB16","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181D4AB16","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"27 1","pages":"50-51"},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78144230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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