Pub Date : 2010-05-01DOI: 10.1097/TEN.0B013E3181DFD199
Vishal Gupta, R. Nagpal, S. Venkatraman, A. Patel
Aim: The aim is to describe a very rare case of idiopathic granulomatous hypophysitis presenting as panhypopituitarism on the background of chronic renal failure and type 2 diabetes mellitus. The patient presented with fatigue and episodes of self-terminated hypoglycemia (while on sulfonylurea) as the sole manifestation of panhypopituitarism. The case also highlights the difficulties of identifying patients with hypophysitis in the setting of chronic renal failure. Results: We describe a middle-aged man who presented to us with the sole complaints of early morning fatigue and hypoglycemia (while on glimepiride), with a background history of type 2 diabetes and chronic renal failure. Before visiting our practice, he was repeatedly evaluated for decompensation of renal and cardiovascular disease without much success. When we saw the patient there was no obvious evidence of any endocrine disturbance, especially as the blood pressure was high without any postural drop. It was only when the patient persistently complained of an impaired quality of life due to the fatigue that we decided to chase an endocrine cause for the same. On endocrine evaluation, we diagnosed panhypopituitarism secondary to idiopathic granulomatous hypophysitis. Conclusion: Idiopathic granulomatous hypophysitis is a very rare form of inflammatory pituitary disease. Fewer than 35 cases of biopsy-proven idiopathic granulomatous hypophysitis have been reported in medical literature. This is only the third case of biopsy-proven idiopathic granulomatous hypophysitis reported from India.
{"title":"Idiopathic Granulomatous Hypophysitis Presenting as Panhypopituitarism","authors":"Vishal Gupta, R. Nagpal, S. Venkatraman, A. Patel","doi":"10.1097/TEN.0B013E3181DFD199","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181DFD199","url":null,"abstract":"Aim: The aim is to describe a very rare case of idiopathic granulomatous hypophysitis presenting as panhypopituitarism on the background of chronic renal failure and type 2 diabetes mellitus. The patient presented with fatigue and episodes of self-terminated hypoglycemia (while on sulfonylurea) as the sole manifestation of panhypopituitarism. The case also highlights the difficulties of identifying patients with hypophysitis in the setting of chronic renal failure. Results: We describe a middle-aged man who presented to us with the sole complaints of early morning fatigue and hypoglycemia (while on glimepiride), with a background history of type 2 diabetes and chronic renal failure. Before visiting our practice, he was repeatedly evaluated for decompensation of renal and cardiovascular disease without much success. When we saw the patient there was no obvious evidence of any endocrine disturbance, especially as the blood pressure was high without any postural drop. It was only when the patient persistently complained of an impaired quality of life due to the fatigue that we decided to chase an endocrine cause for the same. On endocrine evaluation, we diagnosed panhypopituitarism secondary to idiopathic granulomatous hypophysitis. Conclusion: Idiopathic granulomatous hypophysitis is a very rare form of inflammatory pituitary disease. Fewer than 35 cases of biopsy-proven idiopathic granulomatous hypophysitis have been reported in medical literature. This is only the third case of biopsy-proven idiopathic granulomatous hypophysitis reported from India.","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"295 1","pages":"102-104"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79678515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-05-01DOI: 10.1097/TEN.0B013E3181DFFED2
J. Dora, Walter Escouto Machado, G. Geib, K. Pêgas, J. Guimarães, Alceu Migliavaca, A. Maia
{"title":"Incidental Thyroid Cancer in Head and Neck Squamous Cell Carcinoma: An Individualized Approach","authors":"J. Dora, Walter Escouto Machado, G. Geib, K. Pêgas, J. Guimarães, Alceu Migliavaca, A. Maia","doi":"10.1097/TEN.0B013E3181DFFED2","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181DFFED2","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"6 1","pages":"112-114"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72749541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-01DOI: 10.1097/TEN.0B013E3181FC469B
Petra Šulentić, B. Spajić, Igor Grubisic, M. Spajić, M. Vrkljan
{"title":"Bilateral Giant Myelolipoma of Adrenal Glands: A Case Report and Review of the Literature","authors":"Petra Šulentić, B. Spajić, Igor Grubisic, M. Spajić, M. Vrkljan","doi":"10.1097/TEN.0B013E3181FC469B","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181FC469B","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"33 1","pages":"274-276"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74566762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-01DOI: 10.1097/TEN.0B013E3181D54A9D
W. H. Yong, Y. Kon, C. Rajasoorya, Park Nam Julian Goh, H. Howe
{"title":"Bilateral Adrenal Haemorrhage and Evans Syndrome as the Initial Presentation of Antiphospholipid Syndrome From Systemic Lupus Erythematosus","authors":"W. H. Yong, Y. Kon, C. Rajasoorya, Park Nam Julian Goh, H. Howe","doi":"10.1097/TEN.0B013E3181D54A9D","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181D54A9D","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"11 1","pages":"66-68"},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90206060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-01DOI: 10.1097/TEN.0B013E3181D4AB95
D. Bell, Patrick J. OʼNeill
{"title":"Hyperandrogenemia in a Postmenopausal Female That is Suppressed With Metformin Can Avoid Unnecessary Surgery","authors":"D. Bell, Patrick J. OʼNeill","doi":"10.1097/TEN.0B013E3181D4AB95","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181D4AB95","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"6 1","pages":"83-85"},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76039668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-01DOI: 10.1097/TEN.0B013E3181C8CF50
S. Acharya, B. Mathew, P. Menon, T. Bandgar, N. Shah
{"title":"Rare Cases of Precocious Puberty With Hypothyroidism: A Case Series With Review of Literature","authors":"S. Acharya, B. Mathew, P. Menon, T. Bandgar, N. Shah","doi":"10.1097/TEN.0B013E3181C8CF50","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181C8CF50","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"52 1","pages":"78-79"},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88800252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-01DOI: 10.1097/TEN.0B013E3181D4BF9A
A. Polistena, G. Cavallaro, D. Cotesta, L. Petramala, C. Letizia, U. Basile, S. Filetti, A. Cavallaro, G. Toma
Introduction: The incidence of pheochromocytomas is about 1–2/100000 in the adult population. Nearly 10% have an extra-adrenal location or multiple locations and are defined as paragangliomas. They might be catecholaminesecreting as ordinary pheochromocytomas or clinically asymptomatic with compression symptoms. Patients and Methods: Three cases of abdominal paraganglioma with different clinical onset are reported. Discussion: Incidentally diagnosed asymptomatic retroperitoneal tumors with secondary hypertension suggest paraganglioma. Increased levels of catecholamine and extra-adrenal lesions identified at CT or MR imaging with positive MIBG scintigraphy support the diagnosis. Optimal care requires a multidisciplinary approach, accurate preoperative exact localization and adequate preoperative medical treatment to reduce perioperative cardiovascular complications.
{"title":"Surgical management of extra-adrenal abdominal paragangliomas: Report of three cases and review of the literature","authors":"A. Polistena, G. Cavallaro, D. Cotesta, L. Petramala, C. Letizia, U. Basile, S. Filetti, A. Cavallaro, G. Toma","doi":"10.1097/TEN.0B013E3181D4BF9A","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181D4BF9A","url":null,"abstract":"Introduction: The incidence of pheochromocytomas is about 1–2/100000 in the adult population. Nearly 10% have an extra-adrenal location or multiple locations and are defined as paragangliomas. They might be catecholaminesecreting as ordinary pheochromocytomas or clinically asymptomatic with compression symptoms. Patients and Methods: Three cases of abdominal paraganglioma with different clinical onset are reported. Discussion: Incidentally diagnosed asymptomatic retroperitoneal tumors with secondary hypertension suggest paraganglioma. Increased levels of catecholamine and extra-adrenal lesions identified at CT or MR imaging with positive MIBG scintigraphy support the diagnosis. Optimal care requires a multidisciplinary approach, accurate preoperative exact localization and adequate preoperative medical treatment to reduce perioperative cardiovascular complications.","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"14 1","pages":"63-65"},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87746335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-01DOI: 10.1097/TEN.0B013E3181D4AB16
G. F. Taboada, Erika A. Caramez, D. A. T. D. Souza, R. A. Pinheiro, M. Vaisman
{"title":"Solitary Iliac Bone Metastasis of a Follicular Thyroid Carcinoma Causing T3-Toxicosis","authors":"G. F. Taboada, Erika A. Caramez, D. A. T. D. Souza, R. A. Pinheiro, M. Vaisman","doi":"10.1097/TEN.0B013E3181D4AB16","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181D4AB16","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"27 1","pages":"50-51"},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78144230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-03-01DOI: 10.1097/TEN.0B013E3181D59778
F. Zheng, Weina Lu, Hong Li, Xue-hong Dong
{"title":"Pituitary Apoplexy Manifested as Subarachnoid Hemorrhage Accompanied by Primary Hypothyroidism: A Case Report","authors":"F. Zheng, Weina Lu, Hong Li, Xue-hong Dong","doi":"10.1097/TEN.0B013E3181D59778","DOIUrl":"https://doi.org/10.1097/TEN.0B013E3181D59778","url":null,"abstract":"","PeriodicalId":50531,"journal":{"name":"Endocrinologist","volume":"42 1","pages":"69-71"},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82524163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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