Introduction: Stroke, a primary global health concern, is the fifth leading cause of death in Bangladesh, with a prevalence of 0.3%. While 85% of stroke cases globally are cerebral infarctions, Asian countries exhibit stroke patients on average 15 years younger than developed countries. Survival studies reveal strokes exceeding coronary events in hypertensive patients. Observational data suggests circadian, circaseptan, and circannual variations in stroke occurrence, with a morning peak. Circadian rhythm in ischemic stroke is higher in the early morning. Thrombotic strokes, influenced by platelet aggregation and fibrinolysis, often occur in the morning. Haemorrhagic strokes result from blood vessel ruptures. Population-specific circadian patterns remain unconfirmed. Aim of the Study: The study aims to find out the relation of circadian variation of stroke. Methods: This cross-sectional study, conducted at Sylhet MAG Osmani Medical College Hospital, Bangladesh, analyzed 100 stroke patients over six months. Ethical approval was obtained, and informed consent was taken. Inclusion criteria covered patients with clinical and imaging stroke diagnoses, while exclusion criteria excluded transient ischemic attack, previous stroke, head injury history, and refusal to participate. Stroke onset time was categorized into four six-hour intervals. Demographic data, risk factors, and comorbidities were recorded, and brain CT scans were performed. Data analysis used SPSS version 22, employing descriptive statistics, Chi-square Test, and Student's t-test. Significance was set at p<0.05. Results were presented in tables. Results: The study involves 100 participants, primarily aged 60-70 (50%), predominantly male (76%), residing 62% in urban and 38% in rural areas. Occupationally, 35% are businessmen, 24% are housewives, and 15% are service holders and laborers. Smoking status shows 58% smokers. Stroke types include 57% ischemic strokes and 39% hemorrhagic strokes. Hypertension (72%) is the significant risk factor. Stroke symptoms predominantly occur between 06:01 and 12:00 (46%). These insights comprehensively understand the study population's demographics, lifestyle, and clinical characteristics. Conclusion: The study established circadian patterns in stroke onset, with the highest frequency between 06:00-12:00 and the lowest between 18:01-24:00. Ischemic stroke was the most common subtype, followed by hemorrhagic stroke and fewer subarachnoid hemorrhages. Managing blood pressure and coagulation during peak onset times could aid stroke prevention, but further extensive studies are needed for validation.
{"title":"Circadian Variation of Stroke in a Tertiary Level Hospital","authors":"Mahmudur Rahman, Md. Matiur Rahman, Moniruzzaman Ahmed, Suman Kanti Chowdhury, Md. Alamgir Hossan, Sayful Hasan, Nazrul Islam, Shakila Rashid","doi":"10.9734/ajmah/2024/v22i3991","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i3991","url":null,"abstract":"Introduction: Stroke, a primary global health concern, is the fifth leading cause of death in Bangladesh, with a prevalence of 0.3%. While 85% of stroke cases globally are cerebral infarctions, Asian countries exhibit stroke patients on average 15 years younger than developed countries. Survival studies reveal strokes exceeding coronary events in hypertensive patients. Observational data suggests circadian, circaseptan, and circannual variations in stroke occurrence, with a morning peak. Circadian rhythm in ischemic stroke is higher in the early morning. Thrombotic strokes, influenced by platelet aggregation and fibrinolysis, often occur in the morning. Haemorrhagic strokes result from blood vessel ruptures. Population-specific circadian patterns remain unconfirmed. \u0000Aim of the Study: The study aims to find out the relation of circadian variation of stroke. \u0000Methods: This cross-sectional study, conducted at Sylhet MAG Osmani Medical College Hospital, Bangladesh, analyzed 100 stroke patients over six months. Ethical approval was obtained, and informed consent was taken. Inclusion criteria covered patients with clinical and imaging stroke diagnoses, while exclusion criteria excluded transient ischemic attack, previous stroke, head injury history, and refusal to participate. Stroke onset time was categorized into four six-hour intervals. Demographic data, risk factors, and comorbidities were recorded, and brain CT scans were performed. Data analysis used SPSS version 22, employing descriptive statistics, Chi-square Test, and Student's t-test. Significance was set at p<0.05. Results were presented in tables. \u0000Results: The study involves 100 participants, primarily aged 60-70 (50%), predominantly male (76%), residing 62% in urban and 38% in rural areas. Occupationally, 35% are businessmen, 24% are housewives, and 15% are service holders and laborers. Smoking status shows 58% smokers. Stroke types include 57% ischemic strokes and 39% hemorrhagic strokes. Hypertension (72%) is the significant risk factor. Stroke symptoms predominantly occur between 06:01 and 12:00 (46%). These insights comprehensively understand the study population's demographics, lifestyle, and clinical characteristics. \u0000Conclusion: The study established circadian patterns in stroke onset, with the highest frequency between 06:00-12:00 and the lowest between 18:01-24:00. Ischemic stroke was the most common subtype, followed by hemorrhagic stroke and fewer subarachnoid hemorrhages. Managing blood pressure and coagulation during peak onset times could aid stroke prevention, but further extensive studies are needed for validation.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140415408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-26DOI: 10.9734/ajmah/2024/v22i3990
Mehera Parveen, Jinat Fatema, Kazi Farhana Begum, B. Chakma, Tanzina lveen Chowdhury, Tripti Rani Das
Background: There are many risk factors of development of preeclampsia among the pregnant women. Objective: The purpose of the present study has set out to assess the relationship between preeclampsia and blood ionized magnesium levels. Methodology: This case-control study was performed in the Department of Obstetrics and Gynaecology, Dhaka Medical College and Hospital from January 2020 to December 2021 for a period of 2(two) years. Pregnant patients who showed preeclampsia were all the amounts of ionized magnesium in venous blood collected from patients with preeclampsia. Additionally, the magnesium levels of age-matched, healthy pregnant women were determined. Results: A total number of 100 pregant women included in this study of which 50 pregnant women were designated as case and the rest 50 pregnant women were control. It has found that serum levels of ionized magnesium were significantly decreased among preeclamptic cases (0.58 ± 0.06) as compared to normal pregnancies (0.72 ± 0.05) (p < 0.001). Using a cut-off value of 0.7 mmol/l, the serum ionized magnesium level was divided into two groups and was compared between cases and controls. The risk of developing preeclampsia was more than 33 (95% CI = 10.9 – 102.1) times higher in pregnant women with serum magnesium level < 0.7 mmol/L than those pregnant women with serum magnesium level 0.7 or > 0.7 mmol/L. Conclusion: Low level of serum ionized magnesium is a risk factor of development of preeclampsia.
{"title":"Risk of Pre-Eclampsia in Women with Low Serum Ionized Magnesium","authors":"Mehera Parveen, Jinat Fatema, Kazi Farhana Begum, B. Chakma, Tanzina lveen Chowdhury, Tripti Rani Das","doi":"10.9734/ajmah/2024/v22i3990","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i3990","url":null,"abstract":"Background: There are many risk factors of development of preeclampsia among the pregnant women. Objective: The purpose of the present study has set out to assess the relationship between preeclampsia and blood ionized magnesium levels. \u0000Methodology: This case-control study was performed in the Department of Obstetrics and Gynaecology, Dhaka Medical College and Hospital from January 2020 to December 2021 for a period of 2(two) years. Pregnant patients who showed preeclampsia were all the amounts of ionized magnesium in venous blood collected from patients with preeclampsia. Additionally, the magnesium levels of age-matched, healthy pregnant women were determined. \u0000Results: A total number of 100 pregant women included in this study of which 50 pregnant women were designated as case and the rest 50 pregnant women were control. It has found that serum levels of ionized magnesium were significantly decreased among preeclamptic cases (0.58 ± 0.06) as compared to normal pregnancies (0.72 ± 0.05) (p < 0.001). Using a cut-off value of 0.7 mmol/l, the serum ionized magnesium level was divided into two groups and was compared between cases and controls. The risk of developing preeclampsia was more than 33 (95% CI = 10.9 – 102.1) times higher in pregnant women with serum magnesium level < 0.7 mmol/L than those pregnant women with serum magnesium level 0.7 or > 0.7 mmol/L. \u0000Conclusion: Low level of serum ionized magnesium is a risk factor of development of preeclampsia.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140428863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Cervical cancer cases are increasing globally, including in Ghana. Nevertheless, despite the increasing prevalence of this ailment among women, there has been a dearth of extensive research conducted on the subject. Research conducted in several countries has shown that individuals who have survived cervical cancer face numerous difficulties, including socioeconomic, medical, and psychological issues. This study aims to investigate the experiences of women in this particular group, with a focus on the psychological, socio-economic, and hurdles encountered when seeking care. Methodology: The study employed an exploratory descriptive qualitative design. The research was carried out in the Tamale Metropolis, with a specific focus on women who have received a diagnosis of the condition and are now receiving treatment at the Tamale Teaching Hospital. Participants for the study were recruited using purposive sampling. Participants were interviewed face-to-face using a semi-structured interview guide. The interviews recorded on tape were transcribed exactly as spoken and subsequently evaluated manually using the content analysis method. Thematic analysis was employed to analyse the results. Findings: The results indicate that women residing in the Tamale Metropolis who have cervical cancer encounter a disturbance in their social lives, as shown by their unsatisfactory interactions with others. While certain close relatives, acquaintances, and colleagues offer support, others are left behind at times of necessity. Recommendations: Policymakers and the government should implement measures to cover the expenses associated with cervical cancer treatment, similar to how it is done for other diseases through the NHIS. Women diagnosed with cervical cancer should undergo counseling to alleviate the psychological distress they experience.
{"title":"Experiences of Women Living with Cervical Cancer: A Study in the Tamale Metropolis","authors":"Emmanuella Rabi Musa, Keren-Happuch Twumasiwaa Boateng","doi":"10.9734/ajmah/2024/v22i3989","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i3989","url":null,"abstract":"Background: Cervical cancer cases are increasing globally, including in Ghana. Nevertheless, despite the increasing prevalence of this ailment among women, there has been a dearth of extensive research conducted on the subject. Research conducted in several countries has shown that individuals who have survived cervical cancer face numerous difficulties, including socioeconomic, medical, and psychological issues. This study aims to investigate the experiences of women in this particular group, with a focus on the psychological, socio-economic, and hurdles encountered when seeking care. \u0000Methodology: The study employed an exploratory descriptive qualitative design. The research was carried out in the Tamale Metropolis, with a specific focus on women who have received a diagnosis of the condition and are now receiving treatment at the Tamale Teaching Hospital. Participants for the study were recruited using purposive sampling. Participants were interviewed face-to-face using a semi-structured interview guide. The interviews recorded on tape were transcribed exactly as spoken and subsequently evaluated manually using the content analysis method. Thematic analysis was employed to analyse the results. \u0000Findings: The results indicate that women residing in the Tamale Metropolis who have cervical cancer encounter a disturbance in their social lives, as shown by their unsatisfactory interactions with others. While certain close relatives, acquaintances, and colleagues offer support, others are left behind at times of necessity. \u0000Recommendations: Policymakers and the government should implement measures to cover the expenses associated with cervical cancer treatment, similar to how it is done for other diseases through the NHIS. Women diagnosed with cervical cancer should undergo counseling to alleviate the psychological distress they experience.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139961452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.9734/ajmah/2024/v22i3986
Manjula S, Krishna Kumar M
Objective: The current survey-based study aims to provide further insights on expert opinion regarding the commonly prescribed PPIs in clinical practice, with a specific focus on the use of oral rabeprazole 20 mg as a treatment for gastroesophageal reflux disease (GERD) maintenance therapy in Indian settings. Methodology: The questionnaire-based survey involving 25 questions collected perspectives of experts across various regions of India regarding the prescription practice of rabeprazole 20 mg and other proton-pump inhibitors (PPIs) for treating GERD symptoms. Results: Out of 512 study participants, 44% reported obesity as the common comorbid condition observed in GERD patients, while 28% noted co-morbid diabetes mellitus. According to 68% of the respondents, rabeprazole demonstrated superiority over other PPIs in terms of quicker onset of action, maintaining intragastric pH >4 over 24 hours’ post-dose, and reduced nighttime heartburn. For GERD patients with functional dyspepsia and gastroparesis, 52% of responders favored the addition of domperidone as a prokinetic drug to the PPI treatment. Moreover, the majority of participants (61.91%) observed that rabeprazole 20 mg did not cause a delay in stomach emptying, nor did it raise somatostatin levels or alter baseline motilin levels in GERD patients. These findings underscore the effectiveness of rabeprazole 20 mg in comparison to omeprazole and lansoprazole. Conclusion: Experts recommended rabeprazole 20 mg as the preferred treatment option over omeprazole and lansoprazole for GERD patients with coexisting obesity and diabetes mellitus conditions. Additionally, over half of the respondents reported using a combination of domperidone and other PPIs for GERD patients with functional dyspepsia and gastroparesis.
{"title":"Expert Opinion on the Prescription Practice of Rabeprazole and Other Common Proton Pump Inhibitors for Patients with Gastroesophageal Reflux Disease","authors":"Manjula S, Krishna Kumar M","doi":"10.9734/ajmah/2024/v22i3986","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i3986","url":null,"abstract":"Objective: The current survey-based study aims to provide further insights on expert opinion regarding the commonly prescribed PPIs in clinical practice, with a specific focus on the use of oral rabeprazole 20 mg as a treatment for gastroesophageal reflux disease (GERD) maintenance therapy in Indian settings. \u0000Methodology: The questionnaire-based survey involving 25 questions collected perspectives of experts across various regions of India regarding the prescription practice of rabeprazole 20 mg and other proton-pump inhibitors (PPIs) for treating GERD symptoms. \u0000Results: Out of 512 study participants, 44% reported obesity as the common comorbid condition observed in GERD patients, while 28% noted co-morbid diabetes mellitus. According to 68% of the respondents, rabeprazole demonstrated superiority over other PPIs in terms of quicker onset of action, maintaining intragastric pH >4 over 24 hours’ post-dose, and reduced nighttime heartburn. For GERD patients with functional dyspepsia and gastroparesis, 52% of responders favored the addition of domperidone as a prokinetic drug to the PPI treatment. Moreover, the majority of participants (61.91%) observed that rabeprazole 20 mg did not cause a delay in stomach emptying, nor did it raise somatostatin levels or alter baseline motilin levels in GERD patients. These findings underscore the effectiveness of rabeprazole 20 mg in comparison to omeprazole and lansoprazole. \u0000Conclusion: Experts recommended rabeprazole 20 mg as the preferred treatment option over omeprazole and lansoprazole for GERD patients with coexisting obesity and diabetes mellitus conditions. Additionally, over half of the respondents reported using a combination of domperidone and other PPIs for GERD patients with functional dyspepsia and gastroparesis.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139775483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.9734/ajmah/2024/v22i3987
D. Asogun, C. Obodeh, I. Okhihan, T. Aziba, J. Edogun, E. O. Oisakede, J. Akhaine
Background: People who are living with HIV/AIDS (PLWHA) often face numerous mental health challenges, such as depression and anxiety disorders. The objective of this scoping review was to systematically analyse and synthesise the existing literature on mental health interventions available for PLWHA in Nigeria. Methods: To conduct this review, a comprehensive search of reputable sources including PUBMED, Google Scholar, Science Direct, Hinari, and African Journal Online (AJOL) was performed. Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) reporting guidelines, a total of 6 studies were identified, spanning from 2007 and 2021, that focused on interventions addressing adverse mental health conditions among PLWHA. Results: The studies were conducted in three different regions across Nigeria, with the highest number of studies conducted in the South-West region (3), followed by the South East region (2), and the North Central region (1). Among the mental health conditions addressed in these studies, depression was the most prevalent (4 out of 6 studies, or 66.7%), followed by depression co-occurring with other mental health conditions (3 out of 6 studies, or 50%). The most commonly utilised interventions in the reviewed studies were cognitive behavioural therapy (CBT) and aerobic exercise delivery, each accounting for 33.3% of the interventions. All of the studies reported positive outcomes in terms of participants' mental health. The majority of the studies (83.3%) involved professional counsellors administering the mental health interventions, followed by physiotherapists (33.3%) and psychotherapists (33.3%). Conclusions: The findings of this review indicate that there is a significantly limited number of implemented interventions addressing the various forms of mental distress experienced by PLWHA, particularly in high prevalence areas of Nigeria. This highlights a crucial research gap and emphasises the need for more interventions that specifically address the mental health needs of PLWHA in Nigeria, taking into consideration the unique challenges and opportunities present in the country.
{"title":"Mental Health Interventions among People Living with HIV/AIDS in Nigeria: A Scoping Review","authors":"D. Asogun, C. Obodeh, I. Okhihan, T. Aziba, J. Edogun, E. O. Oisakede, J. Akhaine","doi":"10.9734/ajmah/2024/v22i3987","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i3987","url":null,"abstract":"Background: People who are living with HIV/AIDS (PLWHA) often face numerous mental health challenges, such as depression and anxiety disorders. The objective of this scoping review was to systematically analyse and synthesise the existing literature on mental health interventions available for PLWHA in Nigeria. \u0000Methods: To conduct this review, a comprehensive search of reputable sources including PUBMED, Google Scholar, Science Direct, Hinari, and African Journal Online (AJOL) was performed. Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) reporting guidelines, a total of 6 studies were identified, spanning from 2007 and 2021, that focused on interventions addressing adverse mental health conditions among PLWHA. \u0000Results: The studies were conducted in three different regions across Nigeria, with the highest number of studies conducted in the South-West region (3), followed by the South East region (2), and the North Central region (1). Among the mental health conditions addressed in these studies, depression was the most prevalent (4 out of 6 studies, or 66.7%), followed by depression co-occurring with other mental health conditions (3 out of 6 studies, or 50%). The most commonly utilised interventions in the reviewed studies were cognitive behavioural therapy (CBT) and aerobic exercise delivery, each accounting for 33.3% of the interventions. All of the studies reported positive outcomes in terms of participants' mental health. The majority of the studies (83.3%) involved professional counsellors administering the mental health interventions, followed by physiotherapists (33.3%) and psychotherapists (33.3%). \u0000Conclusions: The findings of this review indicate that there is a significantly limited number of implemented interventions addressing the various forms of mental distress experienced by PLWHA, particularly in high prevalence areas of Nigeria. This highlights a crucial research gap and emphasises the need for more interventions that specifically address the mental health needs of PLWHA in Nigeria, taking into consideration the unique challenges and opportunities present in the country.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139775375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.9734/ajmah/2024/v22i3987
D. Asogun, C. Obodeh, I. Okhihan, T. Aziba, J. Edogun, E. O. Oisakede, J. Akhaine
Background: People who are living with HIV/AIDS (PLWHA) often face numerous mental health challenges, such as depression and anxiety disorders. The objective of this scoping review was to systematically analyse and synthesise the existing literature on mental health interventions available for PLWHA in Nigeria. Methods: To conduct this review, a comprehensive search of reputable sources including PUBMED, Google Scholar, Science Direct, Hinari, and African Journal Online (AJOL) was performed. Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) reporting guidelines, a total of 6 studies were identified, spanning from 2007 and 2021, that focused on interventions addressing adverse mental health conditions among PLWHA. Results: The studies were conducted in three different regions across Nigeria, with the highest number of studies conducted in the South-West region (3), followed by the South East region (2), and the North Central region (1). Among the mental health conditions addressed in these studies, depression was the most prevalent (4 out of 6 studies, or 66.7%), followed by depression co-occurring with other mental health conditions (3 out of 6 studies, or 50%). The most commonly utilised interventions in the reviewed studies were cognitive behavioural therapy (CBT) and aerobic exercise delivery, each accounting for 33.3% of the interventions. All of the studies reported positive outcomes in terms of participants' mental health. The majority of the studies (83.3%) involved professional counsellors administering the mental health interventions, followed by physiotherapists (33.3%) and psychotherapists (33.3%). Conclusions: The findings of this review indicate that there is a significantly limited number of implemented interventions addressing the various forms of mental distress experienced by PLWHA, particularly in high prevalence areas of Nigeria. This highlights a crucial research gap and emphasises the need for more interventions that specifically address the mental health needs of PLWHA in Nigeria, taking into consideration the unique challenges and opportunities present in the country.
{"title":"Mental Health Interventions among People Living with HIV/AIDS in Nigeria: A Scoping Review","authors":"D. Asogun, C. Obodeh, I. Okhihan, T. Aziba, J. Edogun, E. O. Oisakede, J. Akhaine","doi":"10.9734/ajmah/2024/v22i3987","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i3987","url":null,"abstract":"Background: People who are living with HIV/AIDS (PLWHA) often face numerous mental health challenges, such as depression and anxiety disorders. The objective of this scoping review was to systematically analyse and synthesise the existing literature on mental health interventions available for PLWHA in Nigeria. \u0000Methods: To conduct this review, a comprehensive search of reputable sources including PUBMED, Google Scholar, Science Direct, Hinari, and African Journal Online (AJOL) was performed. Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) reporting guidelines, a total of 6 studies were identified, spanning from 2007 and 2021, that focused on interventions addressing adverse mental health conditions among PLWHA. \u0000Results: The studies were conducted in three different regions across Nigeria, with the highest number of studies conducted in the South-West region (3), followed by the South East region (2), and the North Central region (1). Among the mental health conditions addressed in these studies, depression was the most prevalent (4 out of 6 studies, or 66.7%), followed by depression co-occurring with other mental health conditions (3 out of 6 studies, or 50%). The most commonly utilised interventions in the reviewed studies were cognitive behavioural therapy (CBT) and aerobic exercise delivery, each accounting for 33.3% of the interventions. All of the studies reported positive outcomes in terms of participants' mental health. The majority of the studies (83.3%) involved professional counsellors administering the mental health interventions, followed by physiotherapists (33.3%) and psychotherapists (33.3%). \u0000Conclusions: The findings of this review indicate that there is a significantly limited number of implemented interventions addressing the various forms of mental distress experienced by PLWHA, particularly in high prevalence areas of Nigeria. This highlights a crucial research gap and emphasises the need for more interventions that specifically address the mental health needs of PLWHA in Nigeria, taking into consideration the unique challenges and opportunities present in the country.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139834885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.9734/ajmah/2024/v22i3986
Manjula S, Krishna Kumar M
Objective: The current survey-based study aims to provide further insights on expert opinion regarding the commonly prescribed PPIs in clinical practice, with a specific focus on the use of oral rabeprazole 20 mg as a treatment for gastroesophageal reflux disease (GERD) maintenance therapy in Indian settings. Methodology: The questionnaire-based survey involving 25 questions collected perspectives of experts across various regions of India regarding the prescription practice of rabeprazole 20 mg and other proton-pump inhibitors (PPIs) for treating GERD symptoms. Results: Out of 512 study participants, 44% reported obesity as the common comorbid condition observed in GERD patients, while 28% noted co-morbid diabetes mellitus. According to 68% of the respondents, rabeprazole demonstrated superiority over other PPIs in terms of quicker onset of action, maintaining intragastric pH >4 over 24 hours’ post-dose, and reduced nighttime heartburn. For GERD patients with functional dyspepsia and gastroparesis, 52% of responders favored the addition of domperidone as a prokinetic drug to the PPI treatment. Moreover, the majority of participants (61.91%) observed that rabeprazole 20 mg did not cause a delay in stomach emptying, nor did it raise somatostatin levels or alter baseline motilin levels in GERD patients. These findings underscore the effectiveness of rabeprazole 20 mg in comparison to omeprazole and lansoprazole. Conclusion: Experts recommended rabeprazole 20 mg as the preferred treatment option over omeprazole and lansoprazole for GERD patients with coexisting obesity and diabetes mellitus conditions. Additionally, over half of the respondents reported using a combination of domperidone and other PPIs for GERD patients with functional dyspepsia and gastroparesis.
{"title":"Expert Opinion on the Prescription Practice of Rabeprazole and Other Common Proton Pump Inhibitors for Patients with Gastroesophageal Reflux Disease","authors":"Manjula S, Krishna Kumar M","doi":"10.9734/ajmah/2024/v22i3986","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i3986","url":null,"abstract":"Objective: The current survey-based study aims to provide further insights on expert opinion regarding the commonly prescribed PPIs in clinical practice, with a specific focus on the use of oral rabeprazole 20 mg as a treatment for gastroesophageal reflux disease (GERD) maintenance therapy in Indian settings. \u0000Methodology: The questionnaire-based survey involving 25 questions collected perspectives of experts across various regions of India regarding the prescription practice of rabeprazole 20 mg and other proton-pump inhibitors (PPIs) for treating GERD symptoms. \u0000Results: Out of 512 study participants, 44% reported obesity as the common comorbid condition observed in GERD patients, while 28% noted co-morbid diabetes mellitus. According to 68% of the respondents, rabeprazole demonstrated superiority over other PPIs in terms of quicker onset of action, maintaining intragastric pH >4 over 24 hours’ post-dose, and reduced nighttime heartburn. For GERD patients with functional dyspepsia and gastroparesis, 52% of responders favored the addition of domperidone as a prokinetic drug to the PPI treatment. Moreover, the majority of participants (61.91%) observed that rabeprazole 20 mg did not cause a delay in stomach emptying, nor did it raise somatostatin levels or alter baseline motilin levels in GERD patients. These findings underscore the effectiveness of rabeprazole 20 mg in comparison to omeprazole and lansoprazole. \u0000Conclusion: Experts recommended rabeprazole 20 mg as the preferred treatment option over omeprazole and lansoprazole for GERD patients with coexisting obesity and diabetes mellitus conditions. Additionally, over half of the respondents reported using a combination of domperidone and other PPIs for GERD patients with functional dyspepsia and gastroparesis.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139835208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.9734/ajmah/2024/v22i2985
Francisco Elías Vargas Merino, Cristóbal Landa Román, Gibran Prudencio Mejía Mejía
In 1948, Steiner conducted an analysis of cancer registries in the United States of America, estimating that primary bone tumors constituted approximately 1% of all fetal malignancies. For its part, in Great Britain, a similar incidence of primary bone tumors is observed, fluctuating between 0.8% and 0.9%. A later statistic from the United States at v of 1.87:1000 000 deaths among children under 14 years of age, increasing to 11.97:1000 000 deaths in people aged 11 to 19 years. Since all bone components are derived from the mesoderm, they have the potential to be composed of any of the four basic types of cells: fibroblasts, chondroblasts, osteoblasts and the reticulo-myelogenous series, to achieve a correct diagnosis it is necessary to have the complementary radiological and pathological support to part of biochemical and hematological investigations. The present investigation focused on a retrospective, observational, quantitative, risk-free study, based on the review of records and tracking of histological reports of patients who were treated at the “Ignacio García Téllez” CMN IMSS Specialty Hospital in a period of 5 years, including all those cases with primary tumors of bone or cartilage origin, both benign and malignant of bone marrow and vascular, in addition to pseudotumor lesions such as fibrous dysplasia, metaphyseal fibrous defect, solitary bone cyst. A total of 182 histological records and reports were recorded in a period of 5 years where a total of 93 women and 89 men were recorded, with ages ranging from 3 months of extrauterine life to 87 years. With a mean of 56.53 years and a standard deviation of 18.48 years. 129 benign tumors were reported in 63 men and 66 women; Meanwhile, a total of 53 malignancies were counted in 26 men and 27 women. The current study facilitates the evaluation of the most common neoplasms in our environment, with the aim of raising awareness about the importance of having adequate resources to develop a timely diagnosis and treatment plan for the benefit of patients.
{"title":"Retrospective Evaluation of Primary Bone Tumors and Their Incidence in the “Ignacio García Téllez” Specialty Hospital CMN IMSS","authors":"Francisco Elías Vargas Merino, Cristóbal Landa Román, Gibran Prudencio Mejía Mejía","doi":"10.9734/ajmah/2024/v22i2985","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i2985","url":null,"abstract":"In 1948, Steiner conducted an analysis of cancer registries in the United States of America, estimating that primary bone tumors constituted approximately 1% of all fetal malignancies. For its part, in Great Britain, a similar incidence of primary bone tumors is observed, fluctuating between 0.8% and 0.9%. A later statistic from the United States at v of 1.87:1000 000 deaths among children under 14 years of age, increasing to 11.97:1000 000 deaths in people aged 11 to 19 years. Since all bone components are derived from the mesoderm, they have the potential to be composed of any of the four basic types of cells: fibroblasts, chondroblasts, osteoblasts and the reticulo-myelogenous series, to achieve a correct diagnosis it is necessary to have the complementary radiological and pathological support to part of biochemical and hematological investigations. The present investigation focused on a retrospective, observational, quantitative, risk-free study, based on the review of records and tracking of histological reports of patients who were treated at the “Ignacio García Téllez” CMN IMSS Specialty Hospital in a period of 5 years, including all those cases with primary tumors of bone or cartilage origin, both benign and malignant of bone marrow and vascular, in addition to pseudotumor lesions such as fibrous dysplasia, metaphyseal fibrous defect, solitary bone cyst. A total of 182 histological records and reports were recorded in a period of 5 years where a total of 93 women and 89 men were recorded, with ages ranging from 3 months of extrauterine life to 87 years. With a mean of 56.53 years and a standard deviation of 18.48 years. 129 benign tumors were reported in 63 men and 66 women; Meanwhile, a total of 53 malignancies were counted in 26 men and 27 women. The current study facilitates the evaluation of the most common neoplasms in our environment, with the aim of raising awareness about the importance of having adequate resources to develop a timely diagnosis and treatment plan for the benefit of patients.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139835978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.9734/ajmah/2024/v22i2985
Francisco Elías Vargas Merino, Cristóbal Landa Román, Gibran Prudencio Mejía Mejía
In 1948, Steiner conducted an analysis of cancer registries in the United States of America, estimating that primary bone tumors constituted approximately 1% of all fetal malignancies. For its part, in Great Britain, a similar incidence of primary bone tumors is observed, fluctuating between 0.8% and 0.9%. A later statistic from the United States at v of 1.87:1000 000 deaths among children under 14 years of age, increasing to 11.97:1000 000 deaths in people aged 11 to 19 years. Since all bone components are derived from the mesoderm, they have the potential to be composed of any of the four basic types of cells: fibroblasts, chondroblasts, osteoblasts and the reticulo-myelogenous series, to achieve a correct diagnosis it is necessary to have the complementary radiological and pathological support to part of biochemical and hematological investigations. The present investigation focused on a retrospective, observational, quantitative, risk-free study, based on the review of records and tracking of histological reports of patients who were treated at the “Ignacio García Téllez” CMN IMSS Specialty Hospital in a period of 5 years, including all those cases with primary tumors of bone or cartilage origin, both benign and malignant of bone marrow and vascular, in addition to pseudotumor lesions such as fibrous dysplasia, metaphyseal fibrous defect, solitary bone cyst. A total of 182 histological records and reports were recorded in a period of 5 years where a total of 93 women and 89 men were recorded, with ages ranging from 3 months of extrauterine life to 87 years. With a mean of 56.53 years and a standard deviation of 18.48 years. 129 benign tumors were reported in 63 men and 66 women; Meanwhile, a total of 53 malignancies were counted in 26 men and 27 women. The current study facilitates the evaluation of the most common neoplasms in our environment, with the aim of raising awareness about the importance of having adequate resources to develop a timely diagnosis and treatment plan for the benefit of patients.
{"title":"Retrospective Evaluation of Primary Bone Tumors and Their Incidence in the “Ignacio García Téllez” Specialty Hospital CMN IMSS","authors":"Francisco Elías Vargas Merino, Cristóbal Landa Román, Gibran Prudencio Mejía Mejía","doi":"10.9734/ajmah/2024/v22i2985","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i2985","url":null,"abstract":"In 1948, Steiner conducted an analysis of cancer registries in the United States of America, estimating that primary bone tumors constituted approximately 1% of all fetal malignancies. For its part, in Great Britain, a similar incidence of primary bone tumors is observed, fluctuating between 0.8% and 0.9%. A later statistic from the United States at v of 1.87:1000 000 deaths among children under 14 years of age, increasing to 11.97:1000 000 deaths in people aged 11 to 19 years. Since all bone components are derived from the mesoderm, they have the potential to be composed of any of the four basic types of cells: fibroblasts, chondroblasts, osteoblasts and the reticulo-myelogenous series, to achieve a correct diagnosis it is necessary to have the complementary radiological and pathological support to part of biochemical and hematological investigations. The present investigation focused on a retrospective, observational, quantitative, risk-free study, based on the review of records and tracking of histological reports of patients who were treated at the “Ignacio García Téllez” CMN IMSS Specialty Hospital in a period of 5 years, including all those cases with primary tumors of bone or cartilage origin, both benign and malignant of bone marrow and vascular, in addition to pseudotumor lesions such as fibrous dysplasia, metaphyseal fibrous defect, solitary bone cyst. A total of 182 histological records and reports were recorded in a period of 5 years where a total of 93 women and 89 men were recorded, with ages ranging from 3 months of extrauterine life to 87 years. With a mean of 56.53 years and a standard deviation of 18.48 years. 129 benign tumors were reported in 63 men and 66 women; Meanwhile, a total of 53 malignancies were counted in 26 men and 27 women. The current study facilitates the evaluation of the most common neoplasms in our environment, with the aim of raising awareness about the importance of having adequate resources to develop a timely diagnosis and treatment plan for the benefit of patients.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139776217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-13DOI: 10.9734/ajmah/2024/v22i2984
Balsam Barkous, K. Kchaou, Chaima Briki, Sirine Jamli, S. Jameleddine
Background: The American Thoracic Society (ATS) and the European Respiratory Society (ERS) have issued several updates to their guidelines for lung function testing between 2005 and 2022. Objective: We aimed to compare ATS/ERS recommendations for 2005(R1) and 2022(R2) in defining Obstructive Ventilatory Impairment (OVI) and in classifying its severity. Patients and Methods: It was a retrospective comparative study including 1129 patients. All patients underwent spirometry with measurement of Forced Expiratory Volume in 1 second (FEV1) and Forced Vital Capacity (FVC). An OVI was considered according to R1 when FEV1/FVC ratio is under the Lower Limit of Normal (LLN) and when the z-score of FEV1/FVC ratio is under -1.645 according to R2. For the severity levels of airflow obstruction: ATS/ERS previously recommended the use of percent predicted FEV1 with 5 levels using cut values of 70%, 60%, 50% and 35%. Recently updated for z-scores with cut values of -2, -2.5 and -4. Mean age was 54.23±19.23 years. Results: For defining an OVI, both definitions were comparable (529 patients with OVI). For the severity classification, the following proportions were assessed: 151 mild, 86 moderate,84 moderately severe, 133 severe and 75 very severe vs 148 mild, 238 moderate, 76 severe and 67 cases having a normal FEV1 (z-score of FEV1 above -1.645), which were classified as mild according to R1. Mild OVI(R2) were distributed according to R1 into 74 mild, 51 moderate, 16 moderately severe and 7 severe. Moderate OVI (R2) were dispatched using R1 to 10 mild, 34 moderate, 66 moderately severe, 103 severe and 25 very severe. Severe OVI(R2) were classified as 1 moderate, 2 moderately severe, 23 severe and 50 very severe. Conclusion: ATS/ERS new and previous recommendations seem to be comparable in defining OVI. However, discrepancies were assessed in classifying its severity.
{"title":"Defining and Grading an Obstructive Ventilatory Impairment: American Thoracic Society/ European Respiratory Society Interpretive Strategies of 2005 Versus 2022","authors":"Balsam Barkous, K. Kchaou, Chaima Briki, Sirine Jamli, S. Jameleddine","doi":"10.9734/ajmah/2024/v22i2984","DOIUrl":"https://doi.org/10.9734/ajmah/2024/v22i2984","url":null,"abstract":"Background: The American Thoracic Society (ATS) and the European Respiratory Society (ERS) have issued several updates to their guidelines for lung function testing between 2005 and 2022. \u0000Objective: We aimed to compare ATS/ERS recommendations for 2005(R1) and 2022(R2) in defining Obstructive Ventilatory Impairment (OVI) and in classifying its severity. \u0000Patients and Methods: It was a retrospective comparative study including 1129 patients. All patients underwent spirometry with measurement of Forced Expiratory Volume in 1 second (FEV1) and Forced Vital Capacity (FVC). An OVI was considered according to R1 when FEV1/FVC ratio is under the Lower Limit of Normal (LLN) and when the z-score of FEV1/FVC ratio is under -1.645 according to R2. For the severity levels of airflow obstruction: ATS/ERS previously recommended the use of percent predicted FEV1 with 5 levels using cut values of 70%, 60%, 50% and 35%. Recently updated for z-scores with cut values of -2, -2.5 and -4. Mean age was 54.23±19.23 years. \u0000Results: For defining an OVI, both definitions were comparable (529 patients with OVI). For the severity classification, the following proportions were assessed: 151 mild, 86 moderate,84 moderately severe, 133 severe and 75 very severe vs 148 mild, 238 moderate, 76 severe and 67 cases having a normal FEV1 (z-score of FEV1 above -1.645), which were classified as mild according to R1. Mild OVI(R2) were distributed according to R1 into 74 mild, 51 moderate, 16 moderately severe and 7 severe. Moderate OVI (R2) were dispatched using R1 to 10 mild, 34 moderate, 66 moderately severe, 103 severe and 25 very severe. Severe OVI(R2) were classified as 1 moderate, 2 moderately severe, 23 severe and 50 very severe. \u0000Conclusion: ATS/ERS new and previous recommendations seem to be comparable in defining OVI. However, discrepancies were assessed in classifying its severity.","PeriodicalId":505327,"journal":{"name":"Asian Journal of Medicine and Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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