Electrical Engineering in Japan最新文献

英文中文

Effects of nanosecond pulsed electric fields application on cancer cell and combination of anticancer drug 纳秒脉冲电场对肿瘤细胞及抗癌药物联合的影响

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-03-02 DOI: 10.1002/eej.23376

Soichiro Enomoto, Daisuke Konishi, Yoshihiro Uto, Naoyuki Shimomura

With the goal of establishing a new cancer treatment method using nanosecond pulsed electric fields (nsPEFs), we investigated the effect of applying nsPEFs and anticancer drugs (adriamycin, ADM) to cancer cells. The surviving fraction of cancer cells was significantly reduced by nsPEFs application compared to the control. Compared to nsPEFs alone and ADM administration alone, a significant decrease of the surviving fraction was observed in combination of nsPEFs application and ADM administration. In addition, multiplying value of surviving fractions of nsPEFs application and ADM administration was calculated as a pseudo-combination effect. The surviving fractions of the experimental combinational results of nsPEFs and ADM were lower than the pseudo-combination results. Therefore, the synergistic effect of combination of nsPEFs and ADM was confirmed. Furthermore, the surviving fraction of ADM administration after nsPEFs application was significantly lower than that of ADM administration on 24 h before nsPEFs application. ADM action on cells would be effective owing to nanopores were formed by applying nsPEFs. It was confirmed that ADM and nsPEF induced apoptosis of cells from apoptosis and necrosis test using FACS.

目标是建立一个新的癌症治疗方法使用纳秒脉冲电场(nsPEFs),我们调查的影响,应用nsPEFs和抗癌药物(阿霉素(ADM)癌细胞。与对照组相比，应用nsPEFs显著降低了癌细胞的存活比例。与单独使用nsPEFs和单独使用ADM相比，nsPEFs和ADM联合使用显著降低了存活分数。此外，计算nsPEFs施用与ADM施用的存活分数的乘积值，作为伪组合效应。幸存的分数nsPEFs和ADM的实验组合结果低于pseudo-combination结果。因此，nsPEFs与ADM联合使用的协同效应得到了证实。此外，施用nsPEFs后ADM的存活率显著低于施用前24 h ADM的存活率。由于施加nspf形成纳米孔，因此ADM对细胞的作用有效。流式细胞术证实ADM和nsPEF均能诱导细胞凋亡。

{"title":"Effects of nanosecond pulsed electric fields application on cancer cell and combination of anticancer drug","authors":"Soichiro Enomoto, Daisuke Konishi, Yoshihiro Uto, Naoyuki Shimomura","doi":"10.1002/eej.23376","DOIUrl":"10.1002/eej.23376","url":null,"abstract":"<p>With the goal of establishing a new cancer treatment method using nanosecond pulsed electric fields (nsPEFs), we investigated the effect of applying nsPEFs and anticancer drugs (adriamycin, ADM) to cancer cells. The surviving fraction of cancer cells was significantly reduced by nsPEFs application compared to the control. Compared to nsPEFs alone and ADM administration alone, a significant decrease of the surviving fraction was observed in combination of nsPEFs application and ADM administration. In addition, multiplying value of surviving fractions of nsPEFs application and ADM administration was calculated as a pseudo-combination effect. The surviving fractions of the experimental combinational results of nsPEFs and ADM were lower than the pseudo-combination results. Therefore, the synergistic effect of combination of nsPEFs and ADM was confirmed. Furthermore, the surviving fraction of ADM administration after nsPEFs application was significantly lower than that of ADM administration on 24 h before nsPEFs application. ADM action on cells would be effective owing to nanopores were formed by applying nsPEFs. It was confirmed that ADM and nsPEF induced apoptosis of cells from apoptosis and necrosis test using FACS.</p>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"215 2","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77933853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Development of dynamic wireless power transfer system for vehicle logistics robot 车载物流机器人动态无线电力传输系统的研制

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-03-02 DOI: 10.1002/eej.23381

Osamu Shimizu, Kazuyoshi Hanabusa, Kota Arasaki, Daisuke Gunji, Yuto Sakai, Hiromori Ikeda, Fuminori Matsuoka

Laborsaving is a major issue in production. In an automotive production line, a yard that is used as a temporary storage for vehicles before shipping. The vehicle-loading robot that operates autonomously has been proposed to automate the alignment of vehicles in the yard instead of human driving. In this study, the dynamic wireless power transfer (DWPT) system that includes the structure of the roadside for the vehicle-loaded robot is proposed. It is proven that the transmitter coil has enough durability for the load of the robot weight using simulation and actual measurement. It is also shown that the reinforcement bars of the road structure cause considerable eddy current loss even with stainless steel. This is similar to loss by coil resistance. This system achieves a 1.8 kW DWPT with an automated coil detection system and a frequency control system, under factory conditions.

节省劳力是生产中的一个主要问题。在汽车生产线上，在装运前用作临时存放车辆的堆场。有人提出，自动操作的车辆装载机器人可以代替人类驾驶，在院子里自动对齐车辆。本文提出了一种包含路边结构的车载机器人动态无线能量传输系统。通过仿真和实际测量，证明了该发射线圈具有足够的耐久性，能够承受机器人的重量。研究还表明，道路结构的钢筋即使采用不锈钢也会造成相当大的涡流损耗。这类似于线圈电阻造成的损耗。在工厂条件下，该系统通过自动线圈检测系统和频率控制系统实现了1.8 kW的DWPT。

引用次数: 0

Parameter determination for reducing ESS capacity in PV power smoothing control using spline function 利用样条函数降低光伏功率平滑控制中ESS容量的参数确定

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-03-01 DOI: 10.1002/eej.23367

Akiko Takahashi, Tatsuya Kajitani, Shigeyuki Funabiki

This paper comprehensively evaluates the PV power smoothing control method using the spline function. As a result of the verification, it is shown that the ESS capacity can be reduced while maintaining the smoothing effect by PV power smoothing control with energy control and limiting fluctuation rate control. Based on the charging/discharging power of the ESS and the operating conditions of the ESS, the section time that achieves both improvement of the smoothing effect and reduction of the ESS capacity is determined to be 1500 s. Then, the rated capacity of the ESS for a rated power of 1.75MW PV system is 1128 kWh. This is 49.6% of the rated capacity of the ESS, which is required in the PV power smoothing control method with fluctuation rate control. As a result of comparing the proposed method and the moving average method, the proposed method improved the smoothing effect by 49.8% compared to the moving average method.

本文综合评价了利用样条函数的光伏功率平滑控制方法。验证结果表明，光伏功率平滑控制结合能量控制和极限波动率控制可以在保持平滑效果的同时减小ESS容量。根据ESS的充放电功率和ESS的运行条件，确定既能提高平滑效果又能降低ESS容量的截面时间为1500 s。则对于1.75MW的光伏系统，ESS的额定容量为1128 kWh。这是具有波动率控制的光伏功率平滑控制方法所要求的ESS额定容量的49.6%。通过与移动平均方法的比较，所提方法的平滑效果比移动平均方法提高了49.8%。

引用次数: 1

Waveform conversion and validation of transient magnetic field due to ESD using equivalent circuit of magnetic near‐field probe 利用磁性近场探头等效电路进行ESD瞬态磁场波形转换与验证

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-02-28 DOI: 10.1002/eej.23371

Jianqing Wang, K. Kawamata, S. Ishigami, Takeshi Ishida, O. Fujiwara

With a 6 GHz band high resolution magnetic near‐field probe (XF‐R 3‐1) produced by Langer, the transient magnetic fields due to collision ESDs (electrostatic discharges) between metal balls at a charging voltage of 600 V were measured near the spark point to investigate a dipole radiation mechanism. In this study, as an object of considering the measured magnetic field waveforms, two different equivalent circuits of the magnetic near‐field probe are derived based on the probe response waveform observed by a TDR (time domain reflectometer) with a 10 ps rise‐time pulse and the probe reflection coefficient measured with a 26 GHz network analyzer. Waveform conversion formulae from the probe output voltage to the magnetic field are given. The validity of the conversion methods is verified by comparing the measured conversion waveforms and their frequency spectra in addition to the converted spectra by the Langer field correction curve with the calculated waveforms of the transient magnetic far‐fields from a dipole model consisting of image charge pairs and the Rompe‐Weizel spark resistance formula. The probe conversion formulae presented here are valid within the frequency range of the 6 GHz probe band, however, beyond the band the resonance peaks at multiple frequencies over 8 GHz appear on the spectra, which causes damping oscillations peculiar to the probe with multiple frequencies to the time domain waveform.

利用Langer公司生产的6 GHz波段高分辨率近场磁探头(XF‐R 3‐1)，测量了金属球在600 V充电电压下碰撞静电放电产生的瞬态磁场，探讨了偶极子辐射机制。本研究以测量的磁场波形为对象，基于10ps上升时间脉冲TDR(时域反射计)观测到的探头响应波形和26ghz网络分析仪测量到的探头反射系数，推导出两种不同的磁场近场探头等效电路。给出了探头输出电压到磁场的波形转换公式。通过将测量到的转换波形及其频谱以及Langer场校正曲线转换后的频谱与由像电荷对组成的偶极子模型和Rompe - Weizel火花电阻公式计算得到的瞬态磁远场波形进行比较，验证了转换方法的有效性。本文提出的探头转换公式在6 GHz探头频带的频率范围内是有效的，但在该频带之外，频谱上出现了多个频率超过8 GHz的共振峰，这导致了多频率探头对时域波形特有的阻尼振荡。

{"title":"Waveform conversion and validation of transient magnetic field due to ESD using equivalent circuit of magnetic near‐field probe","authors":"Jianqing Wang, K. Kawamata, S. Ishigami, Takeshi Ishida, O. Fujiwara","doi":"10.1002/eej.23371","DOIUrl":"https://doi.org/10.1002/eej.23371","url":null,"abstract":"With a 6 GHz band high resolution magnetic near‐field probe (XF‐R 3‐1) produced by Langer, the transient magnetic fields due to collision ESDs (electrostatic discharges) between metal balls at a charging voltage of 600 V were measured near the spark point to investigate a dipole radiation mechanism. In this study, as an object of considering the measured magnetic field waveforms, two different equivalent circuits of the magnetic near‐field probe are derived based on the probe response waveform observed by a TDR (time domain reflectometer) with a 10 ps rise‐time pulse and the probe reflection coefficient measured with a 26 GHz network analyzer. Waveform conversion formulae from the probe output voltage to the magnetic field are given. The validity of the conversion methods is verified by comparing the measured conversion waveforms and their frequency spectra in addition to the converted spectra by the Langer field correction curve with the calculated waveforms of the transient magnetic far‐fields from a dipole model consisting of image charge pairs and the Rompe‐Weizel spark resistance formula. The probe conversion formulae presented here are valid within the frequency range of the 6 GHz probe band, however, beyond the band the resonance peaks at multiple frequencies over 8 GHz appear on the spectra, which causes damping oscillations peculiar to the probe with multiple frequencies to the time domain waveform.","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"19 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78114614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nondistractive extraction of intracellular molecules from yeast using PEF‐assisted autolysis 利用PEF辅助自溶法无干扰提取酵母胞内分子

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-02-22 DOI: 10.1002/eej.23372

Shuji Okamoto, Yoji Murakami, Gen Urabe, S. Katsuki

This paper discusses the possibility of nondestructive extraction of intracellular proteins of yeast (Saccharomyces cerevisiae) by means of pulsed electric fields (PEFs) combined with autolysis. First, the effects of PEFs (20 kV/cm, 600 ns) on yeast and the subsequent cell wall collapse phenomenon were studied by morphological observation of fluorescence staining. Morphological observation shows that the PEFs increase the permeability of the cell membrane and also disrupt the intracellular vacuoles, whereas the cell wall morphology remains unchanged. However, the cell wall was collapse during the postPEF incubation. Next, the amount of extracted protein was evaluated by using the BCA assay. The amount of extracted protein in the PEF treated suspension was only a little, whereas the additional incubation promotes the extraction. Lastly, the size of the extracted proteins was investigated by using both Native‐PAGE and SDS‐PAGE. The PEF‐treated and incubated suspension contains the large protein over 250 kDa.

本文探讨了脉冲电场法结合自溶法无损提取酵母胞内蛋白的可能性。首先，通过荧光染色形态学观察，研究了20 kV/cm, 600 ns的PEFs对酵母的影响以及随后的细胞壁塌缩现象。形态学观察表明，PEFs增加了细胞膜的通透性，也破坏了细胞内的液泡，而细胞壁形态保持不变。然而，在pef后的培养过程中，细胞壁塌陷。接下来，用BCA法评估提取蛋白的量。PEF处理后的悬浮液中提取的蛋白质量很少，而额外的孵育促进了提取。最后，用Native - PAGE和SDS - PAGE对提取蛋白的大小进行了研究。经PEF处理和孵育的悬浮液含有大于250 kDa的大蛋白。

引用次数: 0

Improvement of low‐speed sensorless control with multi‐layer neural network 多层神经网络对低速无传感器控制的改进

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-02-22 DOI: 10.1002/eej.23369

Sari Maekawa, A. Tanaka

In recent years, there has been an increasing demand for position sensorless control in Permanent Magnet Synchronous Motor (PMSM) drives, and various methods have been studied. Switching noise is a problem in the low‐speed sensorless control method that uses the current slope during PWM. Furthermore, another problem is that the inductance does not appear in a sinusoidal distribution owing to magnetic saturation. In this paper, we improve the sensorless control method that estimates the position from the current slope during PWM, which is greatly affected by switching. Additionally, we build a multi‐layer neural network (NN) that directly estimates the position signals by learning a large amount of current data, and verify the driving results in the low‐speed range when the learned NN is incorporated into real‐time control.

近年来，永磁同步电机(PMSM)驱动对无位置传感器控制的需求越来越大，各种方法得到了研究。在低速无传感器控制方法中，开关噪声是一个问题，该方法在PWM过程中使用电流斜率。此外，另一个问题是，由于磁饱和，电感不以正弦分布出现。在本文中，我们改进了无传感器控制方法，该方法在PWM过程中根据电流斜率估计位置，该方法受开关的影响很大。此外，我们构建了一个多层神经网络(NN)，该网络通过学习大量当前数据直接估计位置信号，并将学习到的NN纳入实时控制时，验证低速范围内的驾驶结果。

引用次数: 0

Fabrication of heater‐integrated MEMS tactile sensor for evaluation of warm and cold sensation by touching glass 加热集成MEMS触觉传感器的制造，用于评估触摸玻璃的冷热感觉

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-02-21 DOI: 10.1002/eej.23370

Naotaka Onda, Takaaki Kozuka, Takashi Abe, M. Isshiki, Satoru Tomeno, Masayuki Sohgawa

The paper addresses fabrication and characterization of a MEMS tactile sensor sensitive to force and temperature with an on‐chip heater and a contact part of thermally conductive elastomer. The temperature response of this sensor due to heat transfer when it was in contact with the glass plate was measured. As a result, it is demonstrated that fabricated sensor can detect thermally difference due to differences in the surface treatment of the glass.

本文介绍了一种具有片上加热器和导热弹性体接触部分的对力和温度敏感的MEMS触觉传感器的制造和表征。测量了该传感器与玻璃板接触时由于热传递而产生的温度响应。结果表明，该传感器可以检测到由于玻璃表面处理的不同而产生的热差异。

引用次数: 1

Development of a numerical model for metal vapor dynamics in low pressure arcs based on moving particle semi‐implicit method and influence of shield wall radius on vapor behavior 基于移动粒子半隐式方法的低压电弧中金属蒸气动力学数值模型的建立及屏蔽壁半径对蒸气行为的影响

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-02-21 DOI: 10.1002/eej.23374

T. Miyazaki, Yuto Hatanaka, Yasunori Tanaka, Y. Nakano, T. Ishijima, Gaku Asanuma, T. Onchi

Numerical simulation was conducted for dynamic behavior of copper vapor in arcs under reduced pressure condition using the developed model. The developed model uses MPS method for atoms and ions, while it uses finite volume method for electron energy and electro‐magnetic fields. In this paper, the influence of shield wall inner radius for vapor dynamics was studied on the heavy particle temperature, electron temperature and ionization degree. The particle in MPS method was assumed to be neutralized and mirror‐reflected on the shield wall. As a result, the shield wall with a larger radius causes lower density of metal vapor, lower ionization degree between the electrodes.

利用所建立的模型对低压条件下弧内铜蒸气的动态行为进行了数值模拟。该模型对原子和离子采用MPS法，对电子能量和电磁场采用有限体积法。本文研究了蒸汽动力学中屏蔽壁内半径对重粒子温度、电子温度和电离度的影响。在MPS方法中，假设粒子被中和并在屏蔽壁上镜像反射。因此，屏蔽壁半径越大，金属蒸气密度越低，电极间的电离程度越低。

引用次数: 0

Cross‐regional power supply‐demand analysis model based on clustered unit commitment 基于集群机组承诺的跨区域电力供需分析模型

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-02-21 DOI: 10.1002/eej.23368

Shintaro Negishi, Keisuke Kimura, Ikumi Suzuki, T. Ikegami

In this paper, a new model of electric power supply‐demand analysis based on a clustered unit commitment (CUC) model is proposed. This method enables to derive daily generation plans in multi‐area by minimizing daily generation cost. In the CUC model, the generation units are clustered for the purpose of saving calculation time of the optimization. The proposed model is formulated by Mixed Integer Linear Programming (MILP). The numerical experiment of annual supply‐demand analysis was done to evaluate the availability of the proposed model. As a result, the availability of proposed model was clarified in the view of calculation time and operational results, which are derived by the numerical experiment.

本文提出了一种基于集群单元承诺(CUC)模型的电力供需分析新模型。该方法能够在最小化日发电成本的前提下，得到多区域的日发电计划。在CUC模型中，为了节省优化的计算时间，对发电单元进行了聚类。该模型是用混合整数线性规划(MILP)来表示的。通过年度供需分析的数值实验，验证了该模型的有效性。从计算时间和运行结果两方面验证了该模型的有效性。

引用次数: 0

Power decoupling control of single‐phase or three‐phase input high‐frequency single‐phase output matrix converters 单相或三相输入高频单相输出矩阵变换器的功率解耦控制

IF 0.4 4区工程技术 Q4 Energy

Electrical Engineering in Japan

Pub Date : 2022-02-15 DOI: 10.1002/eej.23366

Wataru Kodaka, S. Ogasawara, K. Orikawa

This study proposes a matrix converter (MC) control method capable of power decoupling (PD) for a single‐phase input isolated AC‐DC converter. The proposed converter can also be fed by a three‐phase source without any additional components. The PD circuit shares its capacitors with the input filters and its switches with the MC, and absorbs the source power ripple to supply a constant DC voltage for the load. Moreover, the MC control method achieves a sinusoidal source current, a high output frequency, and soft switching. Additionally, the feedback control to compensate for the DC output voltage error is applied. The proposed method is evaluated experimentally.

本研究提出了一种能够对单相输入隔离的交直流变换器进行功率解耦(PD)的矩阵变换器控制方法。所提出的变换器也可以由一个三相源供电，而不需要任何额外的组件。PD电路与输入滤波器共用其电容器，与MC共用其开关，并吸收源功率纹波为负载提供恒定的直流电压。此外，MC控制方法实现了正弦源电流、高输出频率和软开关。此外，采用反馈控制补偿直流输出电压误差。实验验证了该方法的有效性。

引用次数: 0

首页上一页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Electrical Engineering in Japan

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀