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Gallbladder malignancy an old soul revisited-ultrasonography and contrast enhanced computed tomography evaluation in tertiary care center in South West Bihar 比哈尔邦西南部三级医疗中心重访胆囊恶性肿瘤--超声波和造影剂增强计算机断层扫描评估
Pub Date : 2024-01-23 DOI: 10.18203/2320-6012.ijrms20240035
Shreya Bhat, M. S. Ahmad, Sachin Sharma, Puja
Background: Gallbladder (GB) malignancy is the commonest biliary tract carcinoma. It ranks fifth among the malignancies of the gastrointestinal tract and in all encompasses about 1-3% of all malignancies. Its peak occurrence is in the 5th decade or older with a female predilection. The most cases of GB malignancy are seen along the Ganga river delta region in India. The median survival rate in GB malignancy is approximately 6 months.Methods: A cross-sectional observational study was conducted in the Department of Radiology, Narayan Medical College and Hospital Sasaram over a period of 12 months from August 2022 to September 2023. A total of 40 patients were included on the basis of signs and symptoms of gallbladder carcinoma and underwent USG and CT scan for preoperative radiological diagnosis, following operation all the resected specimens were sent for histopathological evaluation. The diagnostic accuracies of USG and CT scan were then compared against histopathological diagnosis by using Kappa statistics.Results: In the present study, the mean age of the patients was 60 (range: 40-80 years) with female preponderance. About 40% of the gall-bladder were contracted and reduced in size and 35% large and distended on USG examination, while 45% of the gall-bladder were contracted and reduced in size and 37.5% distended and large on CT examination. Approximately 37.5% had irregularly thickened wall and 25% diffusely thickened wall on USG and 25% of gallbladder wall were diffusely thickened and 45% irregularly thickened on CT scan. The present study showed hepatic parenchymal invasion to be 25% on USG and 37.5% on CT scan. The sensitivity and specificity of USG in diagnosing GB carcinoma were 94.2% and 71.4% respectively. Similarly, the sensitivity and specificity of CT scan in detecting GB carcinoma were 97.1% and 83.3% respectively. The test of agreement (Kappa test) revealed an almost 90% agreement between the two procedures meaning that the two diagnostic modalities are almost comparable in diagnosing gall bladder carcinoma.Conclusions: As the histopathological diagnosis of the present study correlated well with USG and CT scan findings in the diagnosis of gallbladder carcinoma; it can be concluded that both USG and CT scan are useful imaging modalities for diagnosing this disease. However, CT scan is more sensitive and specific in predicting gall bladder carcinoma as compared to USG.
背景:胆囊(GB)恶性肿瘤是最常见的胆道癌。它在胃肠道恶性肿瘤中排名第五,约占所有恶性肿瘤的 1-3%。其发病高峰期在第 5 个 10 年或以上,好发于女性。大多数胃肠道恶性肿瘤病例发生在印度恒河三角洲地区。胃恶性肿瘤的中位生存率约为 6 个月:方法:2022 年 8 月至 2023 年 9 月的 12 个月期间,纳拉扬医学院和萨萨拉姆医院放射科开展了一项横断面观察研究。共有 40 名患者根据胆囊癌的症状和体征被纳入研究,并接受了 USG 和 CT 扫描进行术前放射学诊断。然后用 Kappa 统计法比较 USG 和 CT 扫描与组织病理学诊断的准确性:本研究中,患者的平均年龄为 60 岁(范围:40-80 岁),女性居多。在 USG 检查中,约 40% 的胆囊收缩变小,35% 胆囊膨胀变大;在 CT 检查中,45% 的胆囊收缩变小,37.5% 胆囊膨胀变大。在 USG 检查中,约 37.5% 的胆囊壁不规则增厚,25% 的胆囊壁弥漫性增厚;在 CT 扫描中,25% 的胆囊壁弥漫性增厚,45% 的胆囊壁不规则增厚。本研究显示,USG 和 CT 分别显示 25% 和 37.5% 的肝实质受侵。USG 对诊断 GB 癌的敏感性和特异性分别为 94.2% 和 71.4%。同样,CT 扫描检测胃癌的敏感性和特异性分别为 97.1% 和 83.3%。一致性检验(Kappa 检验)显示,两种方法的一致性接近 90%,这意味着这两种诊断方法在诊断胆囊癌方面几乎不相上下:本研究的组织病理学诊断与 USG 和 CT 扫描在胆囊癌诊断中的结果有很好的相关性,因此可以得出结论,USG 和 CT 扫描都是诊断胆囊癌的有用影像学方法。不过,与 USG 相比,CT 扫描在预测胆囊癌方面更具敏感性和特异性。
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引用次数: 0
Clarithromycin: overview and its current clinical utility in the treatment of respiratory tract infections 克拉霉素:概述及其目前在治疗呼吸道感染中的临床应用
Pub Date : 2024-01-20 DOI: 10.18203/2320-6012.ijrms20240027
Prashant Naik, Divya Prabhat, Rakesh Shrivastava, Arun Nair, D. Khandke
Upper respiratory tract infection (URTI) is a common reason for medical consultation all over the world. Streptococcus A (Strep A) and other infections can cause sore throat as well as pharyngitis or tonsillitis. It may also result in post-infection sequelae, including acute post-streptococcal glomerulonephritis, acute rheumatic fever, and rheumatic heart disease.  As a result, there is a need for an antibiotic that is effective, easy to administer, has a favorable sensitivity pattern, and preferably has some additional pharmacodynamic properties that complement the basic antibacterial profile. Clarithromycin is a macrolide antibacterial agent with broad-spectrum activity against respiratory pathogens. It is especially active against atypical Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella spp. It is well absorbed and stable at gastric pH. It is metabolized by the cytochrome P450 enzymes and forms 14-hydroxy clarithromycin, which is more active than the parent compound, especially against Hemophilus influenzae. It acts by preventing protein synthesis by binding to the 50S subunit of bacterial ribosomes. In dosages of 500 to 1000 mg/day for 5 to 14 days, clarithromycin is effective in the treatment of community-acquired upper and lower respiratory tract infections in hospital and community settings. It exerts significant anti-inflammatory, immunomodulatory, and post-antibiotic effects. It provides a viable option for the treatment of community-acquired respiratory tract infections, in both children and adults.  
上呼吸道感染(URTI)是全世界常见的就诊原因。甲型链球菌(Strep A)和其他感染可引起咽喉痛、咽炎或扁桃体炎。它还可能导致感染后遗症,包括链球菌感染后急性肾小球肾炎、急性风湿热和风湿性心脏病。 因此,我们需要一种有效、易于给药、具有良好敏感性模式的抗生素,最好还具有一些补充基本抗菌特性的药效学特性。克拉霉素是一种大环内酯类抗菌药,对呼吸道病原体具有广谱抗菌活性。它对非典型肺炎衣原体、肺炎支原体和军团菌特别有效。它在细胞色素 P450 酶的作用下进行代谢,形成 14-羟基克拉霉素,其活性高于母体化合物,尤其是对流感嗜血杆菌。它通过与细菌核糖体的 50S 亚基结合来阻止蛋白质合成。克拉霉素的用量为 500 至 1000 毫克/天,疗程 5 至 14 天,可有效治疗医院和社区环境中社区获得性上呼吸道和下呼吸道感染。它具有明显的抗炎、免疫调节和抗生素后效应。它为治疗儿童和成人社区获得性呼吸道感染提供了一种可行的选择。
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引用次数: 0
Hypokalemia-induced arrhythmia: a case series 低钾血症诱发的心律失常:病例系列
Pub Date : 2024-01-20 DOI: 10.18203/2320-6012.ijrms20240028
Ansari Mohammed Shoeb, Shaikh Ashar, Mudassir Ansari
Potassium is one of the major intracellular electrolytes in the body and is normally maintained between 3.5 and 5.5 mEq/L. A serum K+ concentration below 3.5 mEq/L is considered hypokalemia. Electrolyte imbalances, particularly potassium disorders, are common in clinical practice. Potassium homeostasis plays a key role in regulating cell membrane excitability. Potassium is a major determinant of the electrophysiologic properties of the myocardial membrane, and it plays an important role in the occurrence of arrhythmia. Hypokalemia can lead to clinically significant, life-threatening arrhythmia. Typical electrocardiographic (ECG) features of hypokalemia include widespread ST depression, T wave inversion, and prominent U waves. However, hypokalemia may present with different types of arrhythmias as well. Herein, we present 3 cases presenting with hypokalemia-induced arrhythmias in different clinical scenarios with documented low potassium levels and treated with timely diagnosis and effective management. 
钾是人体内主要的细胞内电解质之一,通常维持在 3.5 至 5.5 mEq/L 之间。血清 K+ 浓度低于 3.5 mEq/L 即为低钾血症。电解质失衡,尤其是钾失衡,在临床实践中很常见。钾平衡在调节细胞膜兴奋性方面起着关键作用。钾是心肌膜电生理特性的主要决定因素,在心律失常的发生中起着重要作用。低钾血症可导致临床上严重的、危及生命的心律失常。低钾血症的典型心电图(ECG)特征包括广泛的 ST 压低、T 波倒置和突出的 U 波。然而,低钾血症也可能伴有不同类型的心律失常。在此,我们介绍了 3 例在不同临床情况下出现低钾血症诱发心律失常的病例,这些病例均有低血钾记录,并得到了及时诊断和有效治疗。
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引用次数: 0
Sarcomatous transformation of florid cemento-osseous dysplasia: a case report 骨水泥骨发育不良的肉瘤变:一份病例报告
Pub Date : 2024-01-20 DOI: 10.18203/2320-6012.ijrms20240029
Sailendranath Biswas, A. Saha, Asish K. Das, Shreya Ganguly
Florid cemento-osseous dysplasia (COD) represents a rare group of benign fibro-osseous disorders, while osteogenic sarcoma (OS) on the other hand, is a malignant tumour of ominous prognosis. The malignant transformation of a benign fibro-osseous lesion of the jaw is quite uncommon and has few reported cases. The clinico-radiological findings and histopathological analysis of a lesion present in all four quadrants of the jaw of a patient who reported at the outpatient department of a regional dental college is presented here. The lesion underwent sarcomatous transformation over two months and the findings were confirmed by histopathological evaluation. Although florid cemento-osseous dysplasia is a benign lesion of the jaw with a very low propensity for malignant transformation, it should be closely monitored in patients with tumour predisposition syndromes. Further research and molecular studies are required for better understanding of inadvertent changes.
颌骨纤维骨发育不良(COD)是一类罕见的良性纤维骨疾病,而骨源性肉瘤(OS)则是一种预后不佳的恶性肿瘤。颌骨良性纤维骨病变的恶性转化并不常见,也鲜有报道。本文介绍了一名患者的临床放射学检查结果和组织病理学分析,该患者的病变位于颌骨的四个象限,曾在一所地区牙科学院的门诊部就诊。病变在两个月内发生了肉瘤变,组织病理学评估证实了这一结果。虽然花骨水泥骨发育不良是颌骨的一种良性病变,恶变倾向很低,但对有肿瘤易感综合征的患者应密切监测。为了更好地了解不慎发生的变化,还需要进一步的研究和分子研究。
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引用次数: 0
A comparative and prospective study of ventral hernia repair by laparoscopic and open technique 腹腔镜和开腹技术腹股沟疝修补术的前瞻性对比研究
Pub Date : 2024-01-15 DOI: 10.18203/2320-6012.ijrms20240022
Abhishek Kumar, Sunil Chumber
Background: Ventral hernia repair is becoming more common through laparoscopic techniques; however, there is a lack of comprehensive data on the associated complication rates. We undertook a prospective study to contrast the early establishments of laparoscopic and open ventral hernia surgeries in order to fill this gap. The aim of the study was to assess and contrast the efficiency and reliability of open and laparoscopic techniques for the treatment of ventral hernias.Methods: A prospective study was carried out at All India Institute of Medical Science, New Delhi, India between 2011 and 2014 to assess the dissimilarities between open and laparoscopic approaches in ventral hernia repairs. The study included a total of 40 cases each for open/laparoscopic ventral hernia repair procedures.Results: Eighty cases were investigated, forty of which underwent open repairs and forty of which underwent laparoscopic procedures. In this study, the oldest patient was 77 years old, and the youngest patient was 25 years old. The vast majority (49%) of patients were in their fourth to sixth decades of life. Incisional hernias were in bulk, that had formed from earlier midline lower scars. In both open and laparascopic surgery, there were 40 patients- 43 females and 37 males.  Conclusions: Ventral hernia repair via laparoscopic surgery is showing encouraging results and is currently a widely used technique. When compared to open repairs, it has benefits like decreased postoperative pain, shorter hospital stays, and fewer short-term problems. Laparoscopic hernia surgery also results in a lower risk of wound infections, an earlier restoration of bowel function, and a quicker return to regular activities.
背景:腹股沟疝修补术越来越多地采用腹腔镜技术;然而,目前缺乏相关并发症发生率的全面数据。为了填补这一空白,我们开展了一项前瞻性研究,对比腹腔镜和开腹腹股沟疝手术的早期效果。研究的目的是评估和对比开腹和腹腔镜技术治疗腹股沟疝的效率和可靠性:2011年至2014年期间,印度新德里全印度医学科学研究所开展了一项前瞻性研究,以评估腹股沟疝修补术中开腹和腹腔镜方法的差异。研究包括开放式/腹腔镜腹股沟疝修补术各40例:结果:共调查了 80 例患者,其中 40 例接受了开放式修补术,40 例接受了腹腔镜手术。在这项研究中,年龄最大的患者为 77 岁,最小的患者为 25 岁。绝大多数患者(49%)处于人生的第四至第六个十年。大部分切口疝都是由早期中线下方疤痕形成的。共有 40 名患者接受了开腹和腹腔镜手术,其中女性 43 名,男性 37 名。 结论通过腹腔镜手术进行腹股沟疝修补术的效果令人鼓舞,是目前广泛使用的一种技术。与开腹修补术相比,腹腔镜修补术具有术后疼痛减轻、住院时间缩短、短期问题减少等优点。腹腔镜疝气手术还能降低伤口感染的风险,更早地恢复肠道功能,更快地恢复正常活动。
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引用次数: 0
The prevalence of seroma formation after modified radical mastectomy: an observational analysis of risk factors 改良根治性乳房切除术后血清肿形成的发生率:风险因素观察分析
Pub Date : 2024-01-15 DOI: 10.18203/2320-6012.ijrms20240021
Abhishek Kumar, Sunil Chumber
Background: Seroma, a medically apparent subcutaneous accumulation of effusion fluid after breast carcinoma, growing in 30% of patients. The main hurdle in breast cancer surgery is the formation of a seroma, with an unknown root cause. The objective of this study was to determine the relation between some elements connected with, modified radical mastectomy and seroma formation before the operative period, during the operative period, and after the operative period.Methods: This was an observational study including 200 female patients who were undergoing modified radical mastectomy at All India Institute of Medical Sciences, New Delhi, Delhi from January 2011 to December 2014. After the surgery, the patient was kept under observation for seroma formation. Chi square and t tests were used for the statistical analysis of this study.Results: Seroma formation was more prevalent in old-age patients and overweight patients. The more the initial drain volume the more will be the seroma formation. After the operation, arm physiotherapy was started. 40 patients of older age had the formation of seroma. 30 patients developed seroma whose tumor size was more than 3 cm.Conclusions: The occurrence of seroma was more prominent in older age patients and overweight patients. With prompt physiotherapy and flap fixation under muscles can reduce the occurrence of seroma formation and some interventions in the time of operation can help in decreasing seroma formation.
背景:血清肿是乳腺癌术后医学上明显的皮下积液,有 30% 的患者会出现血清肿。乳腺癌手术的主要障碍是血清肿的形成,其根本原因不明。本研究的目的是确定与改良根治性乳房切除术相关的一些因素与血清肿形成之间在术前、术中和术后的关系:这是一项观察性研究,包括 2011 年 1 月至 2014 年 12 月期间在德里新德里全印度医学科学研究所接受改良根治性乳房切除术的 200 名女性患者。术后观察血清肿形成情况。本研究采用卡方检验和 t 检验进行统计分析:血清肿的形成在老年患者和超重患者中更为普遍。初始引流容量越大,血清肿形成越多。术后开始进行手臂理疗。40 名高龄患者出现血清肿。30名肿瘤大小超过3厘米的患者出现血清肿:结论:血清肿的发生在老年患者和超重患者中更为突出。及时的物理治疗和肌肉下皮瓣固定可减少血清肿的形成,手术时的一些干预措施也有助于减少血清肿的形成。
{"title":"The prevalence of seroma formation after modified radical mastectomy: an observational analysis of risk factors","authors":"Abhishek Kumar, Sunil Chumber","doi":"10.18203/2320-6012.ijrms20240021","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240021","url":null,"abstract":"Background: Seroma, a medically apparent subcutaneous accumulation of effusion fluid after breast carcinoma, growing in 30% of patients. The main hurdle in breast cancer surgery is the formation of a seroma, with an unknown root cause. The objective of this study was to determine the relation between some elements connected with, modified radical mastectomy and seroma formation before the operative period, during the operative period, and after the operative period.\u0000Methods: This was an observational study including 200 female patients who were undergoing modified radical mastectomy at All India Institute of Medical Sciences, New Delhi, Delhi from January 2011 to December 2014. After the surgery, the patient was kept under observation for seroma formation. Chi square and t tests were used for the statistical analysis of this study.\u0000Results: Seroma formation was more prevalent in old-age patients and overweight patients. The more the initial drain volume the more will be the seroma formation. After the operation, arm physiotherapy was started. 40 patients of older age had the formation of seroma. 30 patients developed seroma whose tumor size was more than 3 cm.\u0000Conclusions: The occurrence of seroma was more prominent in older age patients and overweight patients. With prompt physiotherapy and flap fixation under muscles can reduce the occurrence of seroma formation and some interventions in the time of operation can help in decreasing seroma formation.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":" 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139621696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Students’ perspective on absenteeism: a cross-sectional study among students at government medical colleges of Western Maharashtra 学生对旷课的看法:对西马哈拉施特拉邦公立医学院学生的横断面研究
Pub Date : 2024-01-10 DOI: 10.18203/2320-6012.ijrms20240012
Shilpa L. Narayankar, Suraj T. Jadhavar, Saurabh S. Patil, Nikhil R. Gode, Megha S. Kinake, Mansi S. Thokal, Sayli S. Dhande
Background: The professional courses as undergraduate medical education need high theoretical and clinical classes attendance as those students will be future doctors and will deal with the health and disease of the public. In spite of implementing strict policies regarding student attendance, the rate of absenteeism in medical colleges remains high and is a growing apprehension a phenomenon that is also on the rise in universities worldwide.Methods: A cross-sectional study in few Governments Medical Colleges of Western region of Maharashtra using a self-administered questionnaire. Data was collected and analysed through Google forms.Results: Preparatory leave before every examination required (50.7%), air-conditioned classrooms (49.7%), good ventilated classrooms (44.1%), interactive teachers (41.8%), decrease lecture duration (38%), more practical less theory classes (37.6%) and good transportation facilities (34.3%) were various major suggestions given by students to increase the overall attendance.Conclusions: Feedback from students must be repeatedly considered while designing and revising the curriculum to reduce absenteeism.
背景:作为本科医学教育的专业课程,需要很高的理论和临床出勤率,因为这些学生将是未来的医生,要与公众的健康和疾病打交道。尽管实施了严格的学生出勤率政策,但医学院的旷课率仍然很高,而且越来越令人担忧,这一现象在全世界的大学中也呈上升趋势:在马哈拉施特拉邦西部地区的几所政府医学院进行了一项横断面研究,采用自填问卷的方式。通过谷歌表格收集和分析数据:每次考试前都需要请预备假(50.7%)、有空调的教室(49.7%)、通风良好的教室(44.1%)、互动型教师(41.8%)、缩短授课时间(38%)、多实践少理论课(37.6%)和良好的交通设施(34.3%)是学生为提高总体出勤率而提出的各种主要建议:结论:在设计和修订课程时,必须反复考虑学生的反馈意见,以减少旷课现象。
{"title":"Students’ perspective on absenteeism: a cross-sectional study among students at government medical colleges of Western Maharashtra","authors":"Shilpa L. Narayankar, Suraj T. Jadhavar, Saurabh S. Patil, Nikhil R. Gode, Megha S. Kinake, Mansi S. Thokal, Sayli S. Dhande","doi":"10.18203/2320-6012.ijrms20240012","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240012","url":null,"abstract":"Background: The professional courses as undergraduate medical education need high theoretical and clinical classes attendance as those students will be future doctors and will deal with the health and disease of the public. In spite of implementing strict policies regarding student attendance, the rate of absenteeism in medical colleges remains high and is a growing apprehension a phenomenon that is also on the rise in universities worldwide.\u0000Methods: A cross-sectional study in few Governments Medical Colleges of Western region of Maharashtra using a self-administered questionnaire. Data was collected and analysed through Google forms.\u0000Results: Preparatory leave before every examination required (50.7%), air-conditioned classrooms (49.7%), good ventilated classrooms (44.1%), interactive teachers (41.8%), decrease lecture duration (38%), more practical less theory classes (37.6%) and good transportation facilities (34.3%) were various major suggestions given by students to increase the overall attendance.\u0000Conclusions: Feedback from students must be repeatedly considered while designing and revising the curriculum to reduce absenteeism.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":" 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139627626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, risk factors, causative organism and antibiotic susceptibility of catheter associated urinary tract infections 导尿管相关尿路感染的发病率、风险因素、致病菌和抗生素敏感性
Pub Date : 2023-12-28 DOI: 10.18203/2320-6012.ijrms20233997
Rajesh Venkataraman, Gloriya Grifth Manuel, Jeevan Rai N., Shahasanu R. S., Akshay S. R., Eldho Paul, Muhammed Sanib
Background: The most common nosocomial infection is catheter-associated urinary tract infection (CAUTI), with a 3-7% daily risk of developing CAUTI in acute care settings. This study's goal was to identify the prevalence, risk factors, causative organism of CAUTI and understanding the organism's current antimicrobial agent sensitivity profile. Methods: Total 120 patients participated in a prospective and observational study conducted at Adichunchanagiri Hospital, Karnataka. Reviewing and evaluating patient case sheets, laboratory results, and treatment charts of participants who were hospital inpatients provided data needed for the study. Microsoft Excel was used to enter the data and version 28 of SPSS to analyze the data. Statistical significance was determined by using a P-value of less than 0.05. Results: It was discovered that 12.5% of HAI cases were linked to catheter use. The most prevalent microbial agent in the current investigation was E. coli (41.7%). According to the current study, women are more likely than men to get UTIs. An underlying medical condition was found to have a strong correlation with UTIs in the current investigation. For CAUTI, drug resistance to cefotaxime and tigecycline was noted. Conclusions: The study suggested that gender, age extremes, use of antibiotics, length of stay in intensive care unit, diabetes mellitus, immunosuppressive medication, and indwelling urinary devices are the major risk factors for CAUTI. E. coli was the most common microbiological agent in the current study. Therefore, to assist doctors in the treatment and management of CAUTIs, ongoing surveillance of antimicrobial resistance patterns is required.
背景:最常见的院内感染是导尿管相关性尿路感染(CAUTI),在急诊护理环境中,每天发生 CAUTI 的风险为 3-7%。本研究旨在确定 CAUTI 的发病率、风险因素和致病菌,并了解该病菌目前对抗菌药物的敏感性。研究方法共有 120 名患者参与了在卡纳塔克邦 Adichunchanagiri 医院进行的前瞻性观察研究。审查和评估住院病人的病例表、化验结果和治疗图表为研究提供了所需数据。研究人员使用 Microsoft Excel 输入数据,并使用 SPSS 28 版本分析数据。统计意义以 P 值小于 0.05 为准。结果发现 12.5% 的 HAI 病例与导管的使用有关。本次调查中最常见的微生物病原体是大肠杆菌(41.7%)。根据目前的研究,女性比男性更容易感染尿道炎。在本次调查中发现,潜在的医疗状况与尿道炎密切相关。在 CAUTI 中,发现了对头孢他啶和替加环素的耐药性。结论研究表明,性别、极端年龄、使用抗生素、重症监护室住院时间、糖尿病、免疫抑制药物和留置尿管是导致 CAUTI 的主要风险因素。大肠杆菌是本次研究中最常见的微生物病原体。因此,为了协助医生治疗和管理 CAUTI,需要对抗菌素耐药性模式进行持续监测。
{"title":"Prevalence, risk factors, causative organism and antibiotic susceptibility of catheter associated urinary tract infections","authors":"Rajesh Venkataraman, Gloriya Grifth Manuel, Jeevan Rai N., Shahasanu R. S., Akshay S. R., Eldho Paul, Muhammed Sanib","doi":"10.18203/2320-6012.ijrms20233997","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233997","url":null,"abstract":"Background: The most common nosocomial infection is catheter-associated urinary tract infection (CAUTI), with a 3-7% daily risk of developing CAUTI in acute care settings. This study's goal was to identify the prevalence, risk factors, causative organism of CAUTI and understanding the organism's current antimicrobial agent sensitivity profile. Methods: Total 120 patients participated in a prospective and observational study conducted at Adichunchanagiri Hospital, Karnataka. Reviewing and evaluating patient case sheets, laboratory results, and treatment charts of participants who were hospital inpatients provided data needed for the study. Microsoft Excel was used to enter the data and version 28 of SPSS to analyze the data. Statistical significance was determined by using a P-value of less than 0.05. Results: It was discovered that 12.5% of HAI cases were linked to catheter use. The most prevalent microbial agent in the current investigation was E. coli (41.7%). According to the current study, women are more likely than men to get UTIs. An underlying medical condition was found to have a strong correlation with UTIs in the current investigation. For CAUTI, drug resistance to cefotaxime and tigecycline was noted. Conclusions: The study suggested that gender, age extremes, use of antibiotics, length of stay in intensive care unit, diabetes mellitus, immunosuppressive medication, and indwelling urinary devices are the major risk factors for CAUTI. E. coli was the most common microbiological agent in the current study. Therefore, to assist doctors in the treatment and management of CAUTIs, ongoing surveillance of antimicrobial resistance patterns is required.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"24 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139148546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of frontal flap for reconstruction of malar region following arteriovenous malformation resection: a case report 使用额部皮瓣重建动静脉畸形切除术后的耳轮区:病例报告
Pub Date : 2023-12-28 DOI: 10.18203/2320-6012.ijrms20234006
Francisco A. Olvera Yarza, Fernando Téllez Pallares, Aldo Lara Mejía, Miguel Jiménez Yarza, Enrique E. Pérez Guzmán
Arteriovenous malformations (AVMs) are rare congenital vascular anomalies characterized by abnormal artery-vein connections. These malformations often occur intracranially but can be found in extracranial regions, presenting unique clinical challenges. Diagnosis and staging, typically using the Schobinger clinical classification, are essential, and various imaging techniques aid in the process. Treatment of AVMs is a multidisciplinary effort, with minimally invasive endovascular procedures being preferred, and surgical resection considered for extensive cases. In this case report, a 52-year-old male with an AVM in the malar region underwent successful treatment. The procedure involved preoperative marking, anesthesia, flap division, AVM resection, and flap placement, followed by suturing and a second surgical stage. The successful utilization of a contralateral frontal flap for reconstruction following AVM resection is highlighted. This case underscores the importance of a multi-stage surgical approach and careful flap preservation in AVM treatment, emphasizing the skills of surgeons. Collaboration among various medical specialties is crucial for effectively managing AVMs, combining embolization, resection, and reconstruction for tailored treatment that improves both function and aesthetics.
动静脉畸形(AVM)是一种罕见的先天性血管畸形,其特点是动脉-静脉连接异常。这些畸形通常发生在颅内,但也可能出现在颅外,给临床带来独特的挑战。诊断和分期(通常采用 Schobinger 临床分类法)至关重要,而各种成像技术则有助于诊断和分期。动静脉畸形的治疗需要多学科合作,首选微创血管内手术,大面积病例可考虑手术切除。在本病例报告中,一名 52 岁的男性成功接受了颊部 AVM 的治疗。手术过程包括术前标记、麻醉、皮瓣分割、AVM切除和皮瓣置入,然后进行缝合和第二期手术。该病例强调了在切除 AVM 后成功利用对侧额部皮瓣进行重建的重要性。该病例强调了在 AVM 治疗中采用多阶段手术方法和小心保存皮瓣的重要性,并强调了外科医生的技能。各医疗专科之间的合作对于有效治疗 AVM 至关重要,可将栓塞、切除和重建结合起来,进行量身定制的治疗,从而改善功能和美观。
{"title":"Use of frontal flap for reconstruction of malar region following arteriovenous malformation resection: a case report","authors":"Francisco A. Olvera Yarza, Fernando Téllez Pallares, Aldo Lara Mejía, Miguel Jiménez Yarza, Enrique E. Pérez Guzmán","doi":"10.18203/2320-6012.ijrms20234006","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20234006","url":null,"abstract":"Arteriovenous malformations (AVMs) are rare congenital vascular anomalies characterized by abnormal artery-vein connections. These malformations often occur intracranially but can be found in extracranial regions, presenting unique clinical challenges. Diagnosis and staging, typically using the Schobinger clinical classification, are essential, and various imaging techniques aid in the process. Treatment of AVMs is a multidisciplinary effort, with minimally invasive endovascular procedures being preferred, and surgical resection considered for extensive cases. In this case report, a 52-year-old male with an AVM in the malar region underwent successful treatment. The procedure involved preoperative marking, anesthesia, flap division, AVM resection, and flap placement, followed by suturing and a second surgical stage. The successful utilization of a contralateral frontal flap for reconstruction following AVM resection is highlighted. This case underscores the importance of a multi-stage surgical approach and careful flap preservation in AVM treatment, emphasizing the skills of surgeons. Collaboration among various medical specialties is crucial for effectively managing AVMs, combining embolization, resection, and reconstruction for tailored treatment that improves both function and aesthetics.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139149287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathological spectrum in cases of abnormal uterine bleeding: a cross sectional study in tertiary care hospital in Tripura 异常子宫出血病例的组织病理学特征:特里普拉邦三级医院的横断面研究
Pub Date : 2023-12-28 DOI: 10.18203/2320-6012.ijrms20233983
Noni Gopal Reang, Arup Bhaumik, A. Banerjee, Jayanta Roy, Abhijit Datta
Background: Majority women encounter abnormal uterine bleeding in their life where the causes are not limited to cancer even unknown. The actual cause has not been studied in north-east part of India. This data is scarce in State of Tripura. The present study aims to find out histomorphological patterns of AUB reported in AGMC & GBP Hospital in a calendar year. Methods: A cross sectional study was conducted over 2 calendar year from 2021 to 2022 where the cases of AUB irrespective of age, who had undergone endometrial biopsy, endometrial curettage and hysterectomy in Obstetrics and Gynaecology department, AGMC were examined histomorphologically in the dept of Pathology, AGMC. Data were collected in predesigned proforma and analysed using SPSS 21.0 and expressed in both descriptive and inferential statistics. Ethical approval was taken. Results: Total 220 cases of AUB specimens were examined. Among the reported AUB cases, the mean age is 42.5±7.42 year. Overall, 16.81% of the cases of AUB shows normal tissue pattern and 83.19% with abnormal endometrial tissue. Out of 220 sample of AUB, the commonest cause was leiomyoma (20.45%) followed by endometrial hyperplasia (17.27%), adenomyosis (14.54%), mixed tumour lesion (9.09%), endometrial carcinoma (4.54%) and 1.35% shows cervical cancer. Conclusions: Study concluded that In Tripura, majority AUB cases are due to leiomyoma, endometrial hyperplasia, adenomyosis and mixed inflammation indicating proper screening during reproductive stage of the women.
背景:大多数妇女在生活中都会遇到子宫异常出血的情况,其原因不仅限于癌症,甚至是未知的。印度东北部地区尚未对其真正原因进行研究。特里普拉邦的相关数据也很少。本研究旨在了解 AGMC 和 GBP 医院历年报告的 AUB 的组织形态学模式。研究方法:在2021年至2022年的两个日历年中进行了一项横断面研究,在AGMC妇产科接受子宫内膜活检、子宫内膜刮宫术和子宫切除术的AUB病例,不论年龄大小,均在AGMC病理科接受组织形态学检查。数据以预先设计的表格收集,并使用 SPSS 21.0 进行分析,以描述性和推论性统计方法表示。已获得伦理批准。结果共检查了 220 例 AUB 标本。在报告的 AUB 病例中,平均年龄为(42.5±7.42)岁。总体而言,16.81%的 AUB 病例显示组织形态正常,83.19%的病例显示子宫内膜组织异常。在 220 例 AUB 样本中,最常见的病因是子宫肌瘤(20.45%),其次是子宫内膜增生(17.27%)、子宫腺肌病(14.54%)、混合瘤病变(9.09%)、子宫内膜癌(4.54%),1.35%为宫颈癌。结论研究得出结论,在特里普拉邦,大多数 AUB 病例是由子宫肌瘤、子宫内膜增生症、子宫腺肌病和混合性炎症引起的,这表明在妇女的生育阶段应进行适当的筛查。
{"title":"Histopathological spectrum in cases of abnormal uterine bleeding: a cross sectional study in tertiary care hospital in Tripura","authors":"Noni Gopal Reang, Arup Bhaumik, A. Banerjee, Jayanta Roy, Abhijit Datta","doi":"10.18203/2320-6012.ijrms20233983","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233983","url":null,"abstract":"Background: Majority women encounter abnormal uterine bleeding in their life where the causes are not limited to cancer even unknown. The actual cause has not been studied in north-east part of India. This data is scarce in State of Tripura. The present study aims to find out histomorphological patterns of AUB reported in AGMC & GBP Hospital in a calendar year. Methods: A cross sectional study was conducted over 2 calendar year from 2021 to 2022 where the cases of AUB irrespective of age, who had undergone endometrial biopsy, endometrial curettage and hysterectomy in Obstetrics and Gynaecology department, AGMC were examined histomorphologically in the dept of Pathology, AGMC. Data were collected in predesigned proforma and analysed using SPSS 21.0 and expressed in both descriptive and inferential statistics. Ethical approval was taken. Results: Total 220 cases of AUB specimens were examined. Among the reported AUB cases, the mean age is 42.5±7.42 year. Overall, 16.81% of the cases of AUB shows normal tissue pattern and 83.19% with abnormal endometrial tissue. Out of 220 sample of AUB, the commonest cause was leiomyoma (20.45%) followed by endometrial hyperplasia (17.27%), adenomyosis (14.54%), mixed tumour lesion (9.09%), endometrial carcinoma (4.54%) and 1.35% shows cervical cancer. Conclusions: Study concluded that In Tripura, majority AUB cases are due to leiomyoma, endometrial hyperplasia, adenomyosis and mixed inflammation indicating proper screening during reproductive stage of the women.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"39 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139149764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Research in Medical Sciences
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