Pub Date : 2023-11-29DOI: 10.18203/2320-6012.ijrms20233703
Pawika Singh, Vimal Modi, A. K. Singh, Nirmal R. Singh
Background: Bone formation, growth and its vitality necessitates blood supply. Nutrient artery is the key source of blood supply to the long bone apart from the other important sources like periosteal, metaphyseal and epiphyseal arteries. Nutrient foramina allow nutrient artery. Typically, the direction of the nutrient foramina is towards the elbow joint in radius, away from its growing end. Knowledge of foramen index, number, direction and size of the nutrient foramina assists the surgeon to take and exact section of bone in case of bone resection and transplantation techniques. The aim of the present study is to determine the number, position, size direction of the nutrient foramina and the Foramen Index of the human dry radius bones. Methods: In the present study, 100 radius bones of unknown age and sex were taken into consideration from the department of anatomy Index Medical College, Indore (MP), India. Results: Most of the foramen was observed on the anterior surface of the bone. Nutrient foramina was found to be absent in 4 right sided and 3 left sided bones. The foramen index on right side was 34.92±4.97 cm whereas on the left side 34.79±4.43 cm. The nutrient foramen was directed towards the proximal end of radius in all the bones studied. Conclusions: In the present study the average length of the bone and foramina of the size larger are more on the right side when compared to the left side. The foramina are located mostly in the middle third of the bone of the anterior surface. This study may add to the present statistical data available on foramen index number of foramen and their location in the population of Indore region, during recent orthopaedic techniques like bone resection and transplantation.
{"title":"The Indore population's morphometric study of the nutrient foramina of the dried radius","authors":"Pawika Singh, Vimal Modi, A. K. Singh, Nirmal R. Singh","doi":"10.18203/2320-6012.ijrms20233703","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233703","url":null,"abstract":"Background: Bone formation, growth and its vitality necessitates blood supply. Nutrient artery is the key source of blood supply to the long bone apart from the other important sources like periosteal, metaphyseal and epiphyseal arteries. Nutrient foramina allow nutrient artery. Typically, the direction of the nutrient foramina is towards the elbow joint in radius, away from its growing end. Knowledge of foramen index, number, direction and size of the nutrient foramina assists the surgeon to take and exact section of bone in case of bone resection and transplantation techniques. The aim of the present study is to determine the number, position, size direction of the nutrient foramina and the Foramen Index of the human dry radius bones. Methods: In the present study, 100 radius bones of unknown age and sex were taken into consideration from the department of anatomy Index Medical College, Indore (MP), India. Results: Most of the foramen was observed on the anterior surface of the bone. Nutrient foramina was found to be absent in 4 right sided and 3 left sided bones. The foramen index on right side was 34.92±4.97 cm whereas on the left side 34.79±4.43 cm. The nutrient foramen was directed towards the proximal end of radius in all the bones studied. Conclusions: In the present study the average length of the bone and foramina of the size larger are more on the right side when compared to the left side. The foramina are located mostly in the middle third of the bone of the anterior surface. This study may add to the present statistical data available on foramen index number of foramen and their location in the population of Indore region, during recent orthopaedic techniques like bone resection and transplantation.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"152 9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29DOI: 10.18203/2320-6012.ijrms20233739
Joel Thomas, M. Khan, V. Siddini, M. Vankalakunti, H. Ballal
This case report highlights a rare occurrence of nephrotic syndrome in a previously healthy 20-year-old gentleman. The patient exhibited bilateral lower limb swelling, facial puffiness, and abdominal distension. Notably, he had been hospitalized two weeks prior with dengue fever, characterized by a transient reduction in platelet counts. Routine examinations revealed proteinuria, with creatinine at 0.97 and albumin at 2.2. A renal biopsy confirmed focal segmental glomerulosclerosis (FSGS)- NOS type. This case underscores the significance of considering renal complications in individuals with recent dengue fever, especially when presented with atypical symptoms. The scarcity of reported cases depicting nephrotic syndrome as a sequelae to dengue fever further emphasizes the uniqueness of this scenario.
本病例报告重点介绍了一名 20 岁健康男性罕见的肾病综合征。患者表现为双下肢浮肿、面部浮肿和腹胀。值得注意的是，两周前他曾因登革热住院治疗，其特点是血小板计数一过性减少。常规检查发现蛋白尿，肌酐为 0.97，白蛋白为 2.2。肾活检证实为局灶节段性肾小球硬化症（FSGS）- NOS 型。该病例强调了考虑近期登革热患者肾脏并发症的重要性，尤其是在出现非典型症状时。肾病综合征作为登革热后遗症的病例报道很少，这进一步强调了该病例的独特性。
{"title":"When you least expect it: nephrotic syndrome following dengue fever","authors":"Joel Thomas, M. Khan, V. Siddini, M. Vankalakunti, H. Ballal","doi":"10.18203/2320-6012.ijrms20233739","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233739","url":null,"abstract":"This case report highlights a rare occurrence of nephrotic syndrome in a previously healthy 20-year-old gentleman. The patient exhibited bilateral lower limb swelling, facial puffiness, and abdominal distension. Notably, he had been hospitalized two weeks prior with dengue fever, characterized by a transient reduction in platelet counts. Routine examinations revealed proteinuria, with creatinine at 0.97 and albumin at 2.2. A renal biopsy confirmed focal segmental glomerulosclerosis (FSGS)- NOS type. This case underscores the significance of considering renal complications in individuals with recent dengue fever, especially when presented with atypical symptoms. The scarcity of reported cases depicting nephrotic syndrome as a sequelae to dengue fever further emphasizes the uniqueness of this scenario.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29DOI: 10.18203/2320-6012.ijrms20233722
Rogelio A. Blaz Zavala, Alba E. Flores Garcia, Y. E. Corona Flores, Uriel Cruz Calderón, César Reyes Elizondo
Intussusception is an unusual cause of intestinal occlusion in adults, accounting for 5% of cases, and is the result of an underlying pathology in 90% of cases, 60% of which are tumors. The pathogenesis describes the invagination of an intestinal segment into the lumen of an adjacent segment with subsequent alterations in irrigation, risk of necrosis and perforation. Surgical management is indicated in adult patients to restore intestinal transit and to exclude malignancy as the axis of the intussusception. We present the case of a 58-year-old female patient with enteric intussusception at ileum due to lipoma, who underwent bowel resection and manual end-to-end intestinal anastomosis in two planes.
{"title":"Intestinal resection and primary anastomosis as treatment of intussusception due to ileum lipoma: case report and review","authors":"Rogelio A. Blaz Zavala, Alba E. Flores Garcia, Y. E. Corona Flores, Uriel Cruz Calderón, César Reyes Elizondo","doi":"10.18203/2320-6012.ijrms20233722","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233722","url":null,"abstract":"Intussusception is an unusual cause of intestinal occlusion in adults, accounting for 5% of cases, and is the result of an underlying pathology in 90% of cases, 60% of which are tumors. The pathogenesis describes the invagination of an intestinal segment into the lumen of an adjacent segment with subsequent alterations in irrigation, risk of necrosis and perforation. Surgical management is indicated in adult patients to restore intestinal transit and to exclude malignancy as the axis of the intussusception. We present the case of a 58-year-old female patient with enteric intussusception at ileum due to lipoma, who underwent bowel resection and manual end-to-end intestinal anastomosis in two planes.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139212865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29DOI: 10.18203/2320-6012.ijrms20233741
C. C. Chaubal, P. Lawate, Sujit Chaudhury, Ajay Gupta, B. R. Shankar, Sandip Pal, Sharath Kote, Dinesh Patil, Onkar Swami
Gastroesophageal reflux disease (GERD) remains prevalent in medical practice. Proton pump inhibitors (PPIs) are the primary treatment, yet limitations exist. Dexlansoprazole modified release (MR), an R-enantiomer of lansoprazole, offers high efficacy. Its dual release in the duodenum and small intestine yields two peak concentrations at different times (2- and 5-hours post-administration), ensuring the longest maintenance of drug concentration and proton pump inhibitory effect among all PPIs. Dexlansoprazole MR effectively heals erosive esophagitis, maintains healed esophageal mucosa, and controls NERD symptoms. It also improves nocturnal heartburn, GERD-related sleep disturbances, and bothersome regurgitation. Importantly, it maintains good plasma concentration regardless of food intake, enabling flexible dosing. Furthermore, it does not significantly affect clopidogrel metabolism or platelet inhibition, eliminating the need for dose adjustments when co-prescribed. This review highlights dexlansoprazole's unique attributes, pharmacokinetics, advantages, and safety in comparison to traditional PPIs.
{"title":"Efficacy and safety of dexlansoprazole: a comprehensive review","authors":"C. C. Chaubal, P. Lawate, Sujit Chaudhury, Ajay Gupta, B. R. Shankar, Sandip Pal, Sharath Kote, Dinesh Patil, Onkar Swami","doi":"10.18203/2320-6012.ijrms20233741","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233741","url":null,"abstract":"Gastroesophageal reflux disease (GERD) remains prevalent in medical practice. Proton pump inhibitors (PPIs) are the primary treatment, yet limitations exist. Dexlansoprazole modified release (MR), an R-enantiomer of lansoprazole, offers high efficacy. Its dual release in the duodenum and small intestine yields two peak concentrations at different times (2- and 5-hours post-administration), ensuring the longest maintenance of drug concentration and proton pump inhibitory effect among all PPIs. Dexlansoprazole MR effectively heals erosive esophagitis, maintains healed esophageal mucosa, and controls NERD symptoms. It also improves nocturnal heartburn, GERD-related sleep disturbances, and bothersome regurgitation. Importantly, it maintains good plasma concentration regardless of food intake, enabling flexible dosing. Furthermore, it does not significantly affect clopidogrel metabolism or platelet inhibition, eliminating the need for dose adjustments when co-prescribed. This review highlights dexlansoprazole's unique attributes, pharmacokinetics, advantages, and safety in comparison to traditional PPIs.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139209809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medullary thyroid carcinoma (MTC) accounts for only 4% of thyroid tumors and originates from parafollicular cells secreting calcitonin. However, it accounts for 13% of all thyroid cancer related death. We herein report a case of 50 years male who presented with a right neck swelling measuring 3×2×2 cm for 2 years, which was gradually increasing. Ultrasonography of the neck revealed a hypoechoic nodule in the right lobe of thyroid. There was no relevant family history. Patient was clinically euthyroid. Fine needle aspiration smears showed many dispersed spindle shaped cells and loosely cohesive clusters of cells. Nuclei of these cells are spindle shaped and showing moderate anisokaryosis. Clumps of hyaline material also seen. A provisional diagnosis of MTC spindle cell variant had been made, which was confirmed by histopathology. Early diagnosis of MTC is very important. Because if patient do not have metastatic disease usually cured by total thyroidectomy.
{"title":"Medullary thyroid carcinoma spindle cell variant: a rare case report","authors":"Swati Singh, Sanjeev Kumar Singh, Geeta Maurya, Rashmi","doi":"10.18203/2320-6012.ijrms20233732","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233732","url":null,"abstract":"Medullary thyroid carcinoma (MTC) accounts for only 4% of thyroid tumors and originates from parafollicular cells secreting calcitonin. However, it accounts for 13% of all thyroid cancer related death. We herein report a case of 50 years male who presented with a right neck swelling measuring 3×2×2 cm for 2 years, which was gradually increasing. Ultrasonography of the neck revealed a hypoechoic nodule in the right lobe of thyroid. There was no relevant family history. Patient was clinically euthyroid. Fine needle aspiration smears showed many dispersed spindle shaped cells and loosely cohesive clusters of cells. Nuclei of these cells are spindle shaped and showing moderate anisokaryosis. Clumps of hyaline material also seen. A provisional diagnosis of MTC spindle cell variant had been made, which was confirmed by histopathology. Early diagnosis of MTC is very important. Because if patient do not have metastatic disease usually cured by total thyroidectomy.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29DOI: 10.18203/2320-6012.ijrms20233737
Asmita Avinash Kale, Tejas V. Suryavanshi, Komal D. Thorat
This study examined the role of Kabat Rehabilitation and laser therapy in Bell's palsy patient, and its effectiveness in physical and social function. Individuals with Bell's palsy, which produces the facial mimicry, it’s crucial for rehabilitation of facial muscle paralysis. PNF enforces and encourages the muscular action on the weaker side of the face, it enables patients with Bell's palsy perform better physically and socially. Therefore, the effectiveness of Kabat therapy in conjunction with Laser was proven in this investigation. The study was conducted at the outpatient department (OPD), Neuro Physiotherapy, Dr. APJ AK COPT. Patient received the Kabat rehabilitation therapy, as well as laser therapy. In this study, results were found significant in HBS and FDI scale comparing pre and post scores by progressing from moderate to normal on grading and progression of 30% on FDI scale. Hence, we conclude that this intervention could be an adjunct intervention in rehabilitation of Bell’s palsy. Physiotherapy Program including Laser therapy and Kabat rehabilitation for 3 weeks had shown significant on the treatment of Bell’s palsy. Hence, it has proven that it could be used as an adjunct intervention on patient with Bell’s palsy.
{"title":"Treatment of Bell’s palsy by combination of Laser and Kabat rehabilitation: a case study","authors":"Asmita Avinash Kale, Tejas V. Suryavanshi, Komal D. Thorat","doi":"10.18203/2320-6012.ijrms20233737","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233737","url":null,"abstract":"This study examined the role of Kabat Rehabilitation and laser therapy in Bell's palsy patient, and its effectiveness in physical and social function. Individuals with Bell's palsy, which produces the facial mimicry, it’s crucial for rehabilitation of facial muscle paralysis. PNF enforces and encourages the muscular action on the weaker side of the face, it enables patients with Bell's palsy perform better physically and socially. Therefore, the effectiveness of Kabat therapy in conjunction with Laser was proven in this investigation. The study was conducted at the outpatient department (OPD), Neuro Physiotherapy, Dr. APJ AK COPT. Patient received the Kabat rehabilitation therapy, as well as laser therapy. In this study, results were found significant in HBS and FDI scale comparing pre and post scores by progressing from moderate to normal on grading and progression of 30% on FDI scale. Hence, we conclude that this intervention could be an adjunct intervention in rehabilitation of Bell’s palsy. Physiotherapy Program including Laser therapy and Kabat rehabilitation for 3 weeks had shown significant on the treatment of Bell’s palsy. Hence, it has proven that it could be used as an adjunct intervention on patient with Bell’s palsy.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139211851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29DOI: 10.18203/2320-6012.ijrms20233704
M. Mili, Debajit Sarma, M. Sarmah, Suhanee Goswami, Krisna Pegu, Linkan Talukdar, Sharmistha Talukdar, Mohsina Siddique
Background: Significant hearing loss affects children globally (1-3/1,000 infants at birth). Early diagnosis (<6 months age) and subsequent early intervention facilitates normal development of language, regardless of the severity of hearing loss. Methods: A hospital-based, descriptive, retrospective study was done in two tertiary-care centres of Upper Assam region, upon total (55 + 46 =) 101 high risk children (<15 years) during a study period of 1 year. Patients were subjected to a questionnaire, and hearing tests (BERA/OAE) were performed. Results: Majority of the cases were <5 years of age, with male preponderance (66.30% cases). NICU graduates with history of ototoxic medications/mechanical ventilation, neonatal hyperbilirubinemia and caregiver concern were the common presenting risk factors identified. Conclusions: 49.50% cases (n=50) suffered from hearing loss [most common was severe degree of hearing loss, n= 24]. 75% cases in AMCH and 63.6% in LMCH with caregiver concern, 55.55% cases in AMCH and 50% in LMCH with past neonatal hyperbilirubinemia; 50% cases with positive family history; and 46.66% NICU graduates tested positive for hearing loss. Ideally, all high risk children <15 years should be screened for hearing loss with earliest intervention and rehabilitation, to enable them to lead a normal life and reduce the burden of handicap in the community.
{"title":"BERA in the detection of hearing loss in high risk children: an observational study in two tertiary care teaching hospitals in upper Assam region","authors":"M. Mili, Debajit Sarma, M. Sarmah, Suhanee Goswami, Krisna Pegu, Linkan Talukdar, Sharmistha Talukdar, Mohsina Siddique","doi":"10.18203/2320-6012.ijrms20233704","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233704","url":null,"abstract":"Background: Significant hearing loss affects children globally (1-3/1,000 infants at birth). Early diagnosis (<6 months age) and subsequent early intervention facilitates normal development of language, regardless of the severity of hearing loss. Methods: A hospital-based, descriptive, retrospective study was done in two tertiary-care centres of Upper Assam region, upon total (55 + 46 =) 101 high risk children (<15 years) during a study period of 1 year. Patients were subjected to a questionnaire, and hearing tests (BERA/OAE) were performed. Results: Majority of the cases were <5 years of age, with male preponderance (66.30% cases). NICU graduates with history of ototoxic medications/mechanical ventilation, neonatal hyperbilirubinemia and caregiver concern were the common presenting risk factors identified. Conclusions: 49.50% cases (n=50) suffered from hearing loss [most common was severe degree of hearing loss, n= 24]. 75% cases in AMCH and 63.6% in LMCH with caregiver concern, 55.55% cases in AMCH and 50% in LMCH with past neonatal hyperbilirubinemia; 50% cases with positive family history; and 46.66% NICU graduates tested positive for hearing loss. Ideally, all high risk children <15 years should be screened for hearing loss with earliest intervention and rehabilitation, to enable them to lead a normal life and reduce the burden of handicap in the community.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139213797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29DOI: 10.18203/2320-6012.ijrms20233715
D. P. K. Wedayanti
Atopic dermatitis (AD) is one of the most common inflammatory skin diseases, affecting more than 20% of the population at some time in their lives. Currently, corticosteroids are generally used for the treatment of AD, although these drugs have the potential to cause more serious side effects. Objective of the study was to find out the role of probiotics in the management of atopic dermatitis in children through a review of previous research. A PubMed search was carried out with the keywords 'atopic dermatitis' and 'probiotic' from databases for the last 10 years (2014-2023). Researchers present the results in narrative form and in table form. A total of 10 articles were included in this study. The research comes from several different countries with the research time being from 2017 to 2022. Each study describes the author, year of study, total sample, type of probiotic, duration of treatment, results and side effects. Giving probiotics to pediatric patients with atopic dermatitis has an impact on reducing SCORAD in evaluation after 2-3 months (8-12 weeks). No significant side effects were found in the included studies.
{"title":"The use of gut microbiota probiotics in the management of atopic dermatitis in children: systematic review","authors":"D. P. K. Wedayanti","doi":"10.18203/2320-6012.ijrms20233715","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233715","url":null,"abstract":"Atopic dermatitis (AD) is one of the most common inflammatory skin diseases, affecting more than 20% of the population at some time in their lives. Currently, corticosteroids are generally used for the treatment of AD, although these drugs have the potential to cause more serious side effects. Objective of the study was to find out the role of probiotics in the management of atopic dermatitis in children through a review of previous research. A PubMed search was carried out with the keywords 'atopic dermatitis' and 'probiotic' from databases for the last 10 years (2014-2023). Researchers present the results in narrative form and in table form. A total of 10 articles were included in this study. The research comes from several different countries with the research time being from 2017 to 2022. Each study describes the author, year of study, total sample, type of probiotic, duration of treatment, results and side effects. Giving probiotics to pediatric patients with atopic dermatitis has an impact on reducing SCORAD in evaluation after 2-3 months (8-12 weeks). No significant side effects were found in the included studies.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-29DOI: 10.18203/2320-6012.ijrms20233731
Vasundhara Saha
Duchenne muscular dystrophy is a progressive disease involving early morbidity and mortality of children. Hence, it becomes essential to address the evolving issues comprehensively according to palliative care principles. Apart from physical issues, psychological, ethical and spiritual concerns affect the quality of life throughout the symptomatic period including the end of life. This case depicts the incomplete management of progressive physical issues as well as psychological, ethical and spiritual concerns of a ten-year-old child and his family. Lack of proper communication and inadequate knowledge about end-of-life care adversely impacts the quality of life of such patients. Understanding of Palliative Care principles helped to gain insight about the lacuna in clinical care of such patients. Knowledge and incorporation of Palliative Care principles is extremely important for any clinician dealing with progressive diseases like Duchenne Muscular Dystrophy and many more. Application of these principles has the potential to enhance the quality of life of patients and their caregivers significantly throughout the course of the disease.
{"title":"The importance of palliative care in Duchenne muscular dystrophy: a reflection","authors":"Vasundhara Saha","doi":"10.18203/2320-6012.ijrms20233731","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233731","url":null,"abstract":"Duchenne muscular dystrophy is a progressive disease involving early morbidity and mortality of children. Hence, it becomes essential to address the evolving issues comprehensively according to palliative care principles. Apart from physical issues, psychological, ethical and spiritual concerns affect the quality of life throughout the symptomatic period including the end of life. This case depicts the incomplete management of progressive physical issues as well as psychological, ethical and spiritual concerns of a ten-year-old child and his family. Lack of proper communication and inadequate knowledge about end-of-life care adversely impacts the quality of life of such patients. Understanding of Palliative Care principles helped to gain insight about the lacuna in clinical care of such patients. Knowledge and incorporation of Palliative Care principles is extremely important for any clinician dealing with progressive diseases like Duchenne Muscular Dystrophy and many more. Application of these principles has the potential to enhance the quality of life of patients and their caregivers significantly throughout the course of the disease.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Coronavirus disease pandemic has affected the entire world and till date, there is no definitive cure for it with prevention of infection and knowledge about the disease being the only proven effective methods to contain it. Healthcare workers (HCWs) are highly susceptible to getting infected and their knowledge about COVID-19 infection has been known to be inversely proportional to the rates of COVID-19 infection. Methods: Cross-sectional questionnaire-based study assessing knowledge, attitude and practices towards COVID-19 preventive measures was carried out amongst HCWs at a tertiary care hospital in North India. Results: Around 95% of HCWs had received training regarding COVID-19 infection and more than 95% HCWs had adequate knowledge about COVID-19 infection. More than 95% HCWs experienced anxiety and fear while monitoring and treating COVID-19 patients. 85% HCWs felt that there is sufficient awareness in the society regarding COVID-19 infection. Most of the respondents followed correct practices for avoidance of COVID-19 infection with around 90% respondents using face masks and practicing frequent hand washing. Social distancing and avoidance of large gatherings was practiced by around 95% respondents. More than 95% respondents had either taken COVID-19 vaccine or wish to take it. Conclusions: The study suggested that the majority of HCWs had good knowledge and positive attitude toward COVID-19 but there are still some lacunae present in the knowledge regarding prevention of COVID 19 infection. Further education and training are required for HCWs so as to fight COVID and prevent its spread in a better way.
{"title":"Knowledge, attitudes and practice among healthcare workers towards COVID-19 in a tertiary care centre in north India","authors":"Neha Mahajan, Neelisha Saroch, Pooja Sharma, Anish Gupta","doi":"10.18203/2320-6012.ijrms20233699","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20233699","url":null,"abstract":"Background: Coronavirus disease pandemic has affected the entire world and till date, there is no definitive cure for it with prevention of infection and knowledge about the disease being the only proven effective methods to contain it. Healthcare workers (HCWs) are highly susceptible to getting infected and their knowledge about COVID-19 infection has been known to be inversely proportional to the rates of COVID-19 infection. Methods: Cross-sectional questionnaire-based study assessing knowledge, attitude and practices towards COVID-19 preventive measures was carried out amongst HCWs at a tertiary care hospital in North India. Results: Around 95% of HCWs had received training regarding COVID-19 infection and more than 95% HCWs had adequate knowledge about COVID-19 infection. More than 95% HCWs experienced anxiety and fear while monitoring and treating COVID-19 patients. 85% HCWs felt that there is sufficient awareness in the society regarding COVID-19 infection. Most of the respondents followed correct practices for avoidance of COVID-19 infection with around 90% respondents using face masks and practicing frequent hand washing. Social distancing and avoidance of large gatherings was practiced by around 95% respondents. More than 95% respondents had either taken COVID-19 vaccine or wish to take it. Conclusions: The study suggested that the majority of HCWs had good knowledge and positive attitude toward COVID-19 but there are still some lacunae present in the knowledge regarding prevention of COVID 19 infection. Further education and training are required for HCWs so as to fight COVID and prevent its spread in a better way.","PeriodicalId":505944,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139209169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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