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Prevalence of Peri-Implant Diseases in Computer-Guided Implant Sites: A Cross-Sectional Study 计算机引导种植体周围疾病的流行:一项横断面研究
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-11 DOI: 10.1111/cid.70061
Praewvanit Asavanamuang, Piyarat Sirirattanagool, Shruti Jain, Lorenzo Tavelli, Matthew Finkelman, Yash Brahmbhatt, Maria Elisa Galarraga-Vinueza

Objective

The present cross-sectional study aimed to determine the prevalence and the risk indicators associated with peri-implant diseases (PIDs) in patients who were subjected to computer-guided implant surgery.

Methods

Patients that were treated and screened during regular maintenance visits at one university center were enrolled in this cross-sectional study. Implants were diagnosed into the categories of peri-implant health, peri-implant mucositis, or peri-implantitis according to the 2017 World Workshop established case definitions. Bivariate and multivariable analyzes were conducted to identify local parameters and patient characteristics as associated risk indicators with PIDs, bleeding on probing (BOP) and marginal bone level (MBL) change.

Results

A total of 115 patients with 417 implants were evaluated during a regular maintenance visit at one university center. Peri-implant mucositis and peri-implantitis prevalence in digitally-guided implant sites were 67.8% and 9.6% at the patient level, respectively. Former and active smokers, active or a history of periodontitis, implant loading time, plaque index (PI), and absence of soft tissue graft were significantly associated with peri-implantitis. Bruxism, gastrointestinal (GI) disorders, and type of oral hygiene aid (OHI) displayed a significant association with peri-implant MBL changes.

Conclusion

The prevalence of peri-implant diseases in digitally-guided implant sites was comparable for mucositis and appeared lower for peri-implantitis when compared to previous outcomes with nondigital guided implant placement. Notably, patient-related factors and local clinical characteristics such as smoking, periodontitis, higher PI scores, and implant loading time were significantly associated with the occurrence of PIDs, while soft tissue grafting had a protective effect.

目的探讨计算机引导下种植体手术患者种植体周围疾病(pid)的患病率及相关危险指标。方法在一所大学中心进行定期维护访问期间接受治疗和筛查的患者纳入本横断面研究。根据2017年世界研讨会建立的病例定义,种植体被诊断为种植体周围健康、种植体周围粘膜炎或种植体周围炎。进行了双变量和多变量分析,以确定局部参数和患者特征作为与pid、探查出血(BOP)和边缘骨水平(MBL)变化相关的风险指标。结果在一所大学中心对115名患者共417颗种植体进行了定期维护访问。数字引导种植体部位的种植体周围黏膜炎和种植体周围炎患病率分别为67.8%和9.6%。前吸烟者和活跃吸烟者、活跃牙周炎史、种植体加载时间、菌斑指数(PI)和缺乏软组织移植物与种植体周围炎显著相关。磨牙症、胃肠道疾病和口腔卫生辅助设备类型与种植体周围MBL变化有显著相关性。结论:与非数字引导种植体放置的结果相比,在数字引导种植体位置的种植体周围疾病的患病率与粘膜炎相当,并且种植体周围疾病的患病率较低。值得注意的是,吸烟、牙周炎、PI评分较高、种植体加载时间等患者相关因素和局部临床特征与pip的发生显著相关,而软组织移植具有保护作用。
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引用次数: 0
Photogrammetry Versus Intraoral Scanning in Complete-Arch Digital Implant Impression: A Systematic Review and Meta-Analysis 摄影测量与口内扫描在全弓数字种植印模中的对比:系统回顾和荟萃分析
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-07 DOI: 10.1111/cid.70059
Alessandro Pozzi, Lorenzo Arcuri, Paolo Carosi, Andrea Laureti, Jimmy Londono, Hom-Lay Wang

Statement of the Problem

The application of digital impressions for complete-arch implant supported fixed dental prostheses (FDP) remains controversial, and data from a systematic review with meta-analysis comparing intraoral scanning (IOS) and stereophotogrammetry (SPG) remain limited.

Purpose

To evaluate and compare the accuracy of currently available digital technologies, specifically IOS and SPG, in capturing complete-arch implant impressions.

Materials and Methods

An electronic and manual search was conducted on May 4, 2024, across PubMed, Embase, and Cochrane CENTRAL databases following PRISMA guidelines. The search targeted studies (excluding case reports) that assessed the in vivo, in vitro, or ex vivo accuracy of IOS and SPG for complete-arch implant impressions. Two investigators screened eligible studies using the QUADAS-2 tool. Accuracy was the primary outcome, including linear, angular, surface deviations, and inter-implant distance. Three meta-analyses were performed on angular deviations, trueness, and surface deviations, trueness, and precision using a random-effect model.

Results

Thirteen studies (3 in vivo and 10 in vitro) met inclusion criteria, displaying methodological heterogeneity (8 analyzing surface, 3 linear, 8 angular, and 3 interimplant distance deviations). The studies evaluated seven IOS (Aoralscan 3, Carestream 3600, iTero Element 2, iTero Element 5D, Primescan, Trios 3, and Trios 4) and two SPG devices (PIC and ICam4D). The number of implants ranged from 4 to 8. SPG reported higher accuracy than IOS in 10 of 13 studies. One in vitro study found IOS to have higher trueness but lower precision, another in vitro study found higher accuracy with IOS, and one in vivo study showed comparable trueness. Meta-analyses of in vitro studies revealed significant differences favoring SPG in surface deviation trueness and precision, and angular deviation trueness (p < 0.05), with reported effects of 3.426, 4.893, and 1.199. SPG showed surface trueness and precision, and angular trueness mean ranges 5.18–48.74 and 0.10–5.46 μm, and 0.24°–0.80°, while IOS ranges 14.8–67.72 and 3.90–37.07 μm, and 0.28°–1.74°.

Conclusions

Within study limitations, SPG showed to be a more reliable technology than IOS for complete-arch digital implant impression, exh

数字印模在全牙弓种植固定义齿(FDP)中的应用仍然存在争议,并且来自比较口内扫描(IOS)和立体摄影测量(SPG)的meta分析系统综述的数据仍然有限。目的评估和比较目前可用的数字技术,特别是IOS和SPG在捕获全弓种植体印模方面的准确性。材料和方法根据PRISMA指南,于2024年5月4日对PubMed、Embase和Cochrane CENTRAL数据库进行了电子和人工检索。搜索目标研究(不包括病例报告),评估IOS和SPG用于全弓植入物印模的体内、体外或离体准确性。两名研究者使用QUADAS-2工具筛选符合条件的研究。准确性是主要结果,包括线性、角度、表面偏差和种植体间距离。采用随机效应模型对角度偏差、真实度、表面偏差、真实度和精度进行了三项荟萃分析。结果13项研究(3项体内研究,10项体外研究)符合纳入标准,存在方法学异质性(8项分析表面偏差,3项分析线性偏差,8项分析角度偏差,3项分析种植体间距离偏差)。研究评估了7个IOS (Aoralscan 3、Carestream 3600、iTero Element 2、iTero Element 5D、Primescan、Trios 3和Trios 4)和2个SPG设备(PIC和ICam4D)。植入物数量从4到8个不等。在13项研究中,有10项报告SPG的准确性高于IOS。一项体外研究发现IOS具有较高的准确性,但精度较低,另一项体外研究发现IOS具有较高的准确性,一项体内研究显示出类似的准确性。体外研究的meta分析显示,SPG在表面偏差真实性和精度以及角偏差真实性方面存在显著差异(p < 0.05),报告效应分别为3.426、4.893和1.199。SPG的表面真实度和精度均值为5.18 ~ 48.74 μm和0.10 ~ 5.46 μm,角真实度均值为0.24°~ 0.80°;IOS的表面真实度均值为14.8 ~ 67.72 μm和3.90 ~ 37.07 μm,角真实度均值为0.28°~ 1.74°。结论在研究范围内,SPG技术比IOS技术更可靠,显示出更高的准确性和准确性。IOS报告的角度偏差超过了被动配合所需的1°阈值。需要进一步的临床试验来获得结论性证据。在此之前,仍然建议使用严格的原型试用。试验注册:CRD42024490844
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引用次数: 0
Correction to “Varying Influence of Maxillary Sinus Dimensions on New Bone Formation With Various Graft Materials in Lateral Window Sinus Augmentation—A Retrospective Study” 纠正“上颌窦侧窗增强术中不同移植材料对新骨形成的不同影响——回顾性研究”
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-05 DOI: 10.1111/cid.70054

S. Krennmair, M. Weinländer, U.Y. Schwarze, M. Malek, T. Forstner, and G. Krennmair, “Varying Influence of Maxillary Sinus Dimensions on New Bone Formation With Various Graft Materials in Lateral Window Sinus Augmentation—A Retrospective Study,” Clinical Implant Dentistry and Related Research 27 (2025): e70014. https://doi.org/10.1111/cid.70014.

In the above article, the presentation of the authors' pre- and family names were incorrect. This has been corrected in the online version of the article and the correct author list is shown below for reference:

Stefan Krennmair | Michael Weinländer | Uwe-Yalcin Schwarze | Michael Malek | Thomas Forstner | Gerald Krennmair

We apologize for this error.

S. Krennmair, M. Weinländer, U.Y. Schwarze, M. Malek, T. Forstner, G. Krennmair,“上颌窦尺寸对侧窗窦增强术中新骨形成的影响-回顾性研究”,临床种植牙医学与相关研究27 (2025):e70014。https://doi.org/10.1111/cid.70014.In上述文章中,作者的前姓和姓的表述有误。这已经在文章的在线版本中进行了更正,正确的作者名单如下所示,以供参考:Stefan Krennmair | Michael Weinländer | Uwe-Yalcin Schwarze | Michael Malek | Thomas Forstner | Gerald Krennmair我们为这个错误道歉。
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引用次数: 0
Correction to “In Vitro and In Vivo Accuracy of Autonomous Robotic vs. Fully Guided Static Computer-Assisted Implant Surgery” 对“自主机器人与完全引导的静态计算机辅助植入手术的体外和体内精度”的更正
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-05 DOI: 10.1111/cid.70060

H. Jin, Z. Qinmeng, W. Xueting, et al., “In Vitro and In Vivo Accuracy of Autonomous Robotic vs. Fully Guided Static Computer-Assisted Implant Surgery,” Clinical Implant Dentistry and Related Research 26 (2024): 385–401, https://doi.org/10.1111/cid.13302.

In Figure 1, panels (d) and (h) were mistakenly duplicated during figure assembly. A corrected version of Figure 1 is provided, with panel (h) properly updated.

In Table 3, the first quartile (Q1) and third quartile (Q3) values for BDA and MDA in the ARI group were transposed. This correction does not affect the statistical significance or the study's conclusions. A revised version of Table 3 is provided.

We apologize for this error.

金辉,赵庆萌,吴雪婷,等,“自主机器人与全引导静态计算机辅助种植手术的体外和体内精度”,临床种植牙科学与相关研究26 (2024):385-401,https://doi.org/10.1111/cid.13302.In图1,面板(d)和(h)在图组装过程中被错误复制。提供了图1的更正版本,并对面板(h)进行了适当更新。在表3中,ARI组BDA和MDA的第一个四分位数(Q1)和第三个四分位数(Q3)值被调换。此修正不影响统计显著性或研究结论。现提供表3的修订本。我们为这个错误道歉。
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引用次数: 0
Comparison of Accuracy and Systematic Precision Between Autonomous Dental Robot and Static Guide: A Retrospective Study 自主式牙科机器人与静态导向器精度及系统精度比较的回顾性研究
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-05 DOI: 10.1111/cid.70050
Na Chen, Yuanyuan Wang, Huawei Zou, Yu Chen, Yuanding Huang

Objective

This study aimed to compare the implant placement accuracy and systematic precision between Robotic-Assisted Implant Surgery (RAIS) and Fully Guided Static Computer-Assisted Implant surgery (sCAIS), as well as to explore factors influencing implant placement accuracy.

Materials and Methods

Patients who underwent digital guided implant surgery between October 2022 and July 2024 were included in this study. The patients were divided into the RAIS and sCAIS groups. Post-operative CBCT scans were performed to measure three-dimensional (3D) deviations and overlap rate (OR) of each implant. The differences in 3D deviations and OR between the two CAIS methods were analyzed, along with factors that could impact implant accuracy, such as anterior versus posterior sites, maxilla versus mandible, bone defects, implant morphology, and free-end sites.

Results

254 patients were enrolled, with 125 patients receiving 227 implants in the RAIS group and 129 patients receiving 227 implants in the sCAIS group. The RAIS group demonstrated significantly better performance than the sCAIS group in coronal global deviation (0.69 [0.52] mm vs. 0.97 [0.64] mm), apical global deviation (0.75 [0.57] mm vs. 1.40 [0.82] mm), angular deviation (1.51 [1.43]° vs. 3.44 [2.78]°), and OR (80 [17]% vs. 64 [20]%) (p < 0.001). There were no significant differences between the two groups in coronal horizontal mesiodistal deviation at the anterior sites, nor in coronal horizontal mesiodistal and buccolingual deviations at the posterior sites.

Conclusion

In most edentulous cases, implant placement accuracy assisted by the RAIS system was significantly higher than that of the sCAIS system. The control of Coronal horizontal (mesiodistal) deviation by sCAIS is comparable to that of RAIS. Additionally, the RAIS system demonstrated better systematic precision.

目的比较机器人辅助种植手术(RAIS)和全引导静态计算机辅助种植手术(sCAIS)的种植体放置精度和系统精度,并探讨影响种植体放置精度的因素。材料与方法本研究纳入2022年10月至2024年7月期间接受数字引导种植手术的患者。患者分为RAIS组和sCAIS组。术后进行CBCT扫描,测量每个种植体的三维(3D)偏差和重叠率(OR)。分析了两种CAIS方法在3D偏差和OR方面的差异,以及影响种植体准确性的因素,如前牙与后牙、上颌骨与下颌骨、骨缺损、种植体形态和游离端位置。结果纳入254例患者,RAIS组125例患者接受227颗种植体,sCAIS组129例患者接受227颗种植体。RAIS组在冠状面整体偏差(0.69 [0.52]mm vs. 0.97 [0.64] mm)、根尖整体偏差(0.75 [0.57]mm vs. 1.40 [0.82] mm)、角度偏差(1.51[1.43]°vs. 3.44[2.78]°)和OR (80 [20]% vs. 64 [20]%) (p < 0.001)方面的表现明显优于sCAIS组。两组在前位冠状体水平中远端偏差、后位冠状体水平中远端偏差和颊舌偏差均无显著差异。结论在大多数无牙病例中,RAIS系统辅助种植体的植入精度明显高于sCAIS系统。sCAIS对冠状水平(中远端)偏移的控制与RAIS相当。此外,RAIS系统显示出更好的系统精度。
{"title":"Comparison of Accuracy and Systematic Precision Between Autonomous Dental Robot and Static Guide: A Retrospective Study","authors":"Na Chen,&nbsp;Yuanyuan Wang,&nbsp;Huawei Zou,&nbsp;Yu Chen,&nbsp;Yuanding Huang","doi":"10.1111/cid.70050","DOIUrl":"https://doi.org/10.1111/cid.70050","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to compare the implant placement accuracy and systematic precision between Robotic-Assisted Implant Surgery (RAIS) and Fully Guided Static Computer-Assisted Implant surgery (sCAIS), as well as to explore factors influencing implant placement accuracy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Patients who underwent digital guided implant surgery between October 2022 and July 2024 were included in this study. The patients were divided into the RAIS and sCAIS groups. Post-operative CBCT scans were performed to measure three-dimensional (3D) deviations and overlap rate (OR) of each implant. The differences in 3D deviations and OR between the two CAIS methods were analyzed, along with factors that could impact implant accuracy, such as anterior versus posterior sites, maxilla versus mandible, bone defects, implant morphology, and free-end sites.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>254 patients were enrolled, with 125 patients receiving 227 implants in the RAIS group and 129 patients receiving 227 implants in the sCAIS group. The RAIS group demonstrated significantly better performance than the sCAIS group in coronal global deviation (0.69 [0.52] mm vs. 0.97 [0.64] mm), apical global deviation (0.75 [0.57] mm vs. 1.40 [0.82] mm), angular deviation (1.51 [1.43]° vs. 3.44 [2.78]°), and OR (80 [17]% vs. 64 [20]%) (<i>p</i> &lt; 0.001). There were no significant differences between the two groups in coronal horizontal mesiodistal deviation at the anterior sites, nor in coronal horizontal mesiodistal and buccolingual deviations at the posterior sites.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In most edentulous cases, implant placement accuracy assisted by the RAIS system was significantly higher than that of the sCAIS system. The control of Coronal horizontal (mesiodistal) deviation by sCAIS is comparable to that of RAIS. Additionally, the RAIS system demonstrated better systematic precision.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144213791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnesium Resorbable Membrane for Guided Bone Regeneration in Critical Size Defect Model in Rabbits—Histomorphometric Analysis 镁可吸收膜引导兔临界尺寸骨缺损模型骨再生-组织形态学分析
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-05 DOI: 10.1111/cid.70055
Ilan Beitlitum, Fatma Rayyan, Gil Slutzkey, Perry Raz, Rachel Sarig

Objectives

To evaluate the effectiveness of a Mg-based membrane as a barrier for guided bone regeneration in rabbits calvaria.

Materials and Methods

Nine rabbits had four critical size defects created in each calvarium, randomly filled with a blood clot or bovine xenograft. One side was covered with the Mg-based membrane, and the control was left without membrane. After 8 weeks, histomorphometric analysis was performed to compare new bone formation with the pristine bone.

Results

Mg-supported membrane for guided bone regeneration (GBR) is safe and promotes bone formation in critical size defects (CSD) in a rabbit calvaria. Gas accumulation was observed in a third of the specimens due to membrane degradation. Histomorphometric analysis revealed greater bone formation in the defects grafted with the Mg membrane (4.85 ± 1.73 mm2) compared to the blood clot (2.14 ± 2.22 mm2). Treating lesions with filler or the magnesium membrane resulted in significantly higher bone formation in all three examined regions (25%–62%). New bone formation was observed beyond the original bone envelope.

Conclusion

Mg-based membrane supports guided bone regeneration (GBR), and when used in combination with a bone graft, enhances the performance despite the gas accumulation associated with membrane degradation.

Clinical Relevance

Limited data exist on the use of Mg-based membranes in GBR and its effect on bone formation.

目的探讨镁基膜在兔颅骨引导骨再生中的作用。材料与方法9只兔每只颅骨上有4个临界大小的缺损,随机填充血凝块或牛异种移植物。一侧覆盖mg基膜,对照组不覆盖膜。8周后,进行组织形态学分析,比较新骨与原始骨的形成情况。结果Mg-supported membrane for guided bone regeneration (GBR)是安全的,并能促进兔颅骨临界尺寸缺损(CSD)的骨形成。由于膜降解,在三分之一的标本中观察到气体积聚。组织形态学分析显示,与血凝块(2.14±2.22 mm2)相比,Mg膜移植缺损的骨形成(4.85±1.73 mm2)更大。用填充物或镁膜治疗病变导致所有三个检查区域的骨形成明显增加(25%-62%)。在原有骨包膜外观察到新骨形成。结论镁基膜支持引导骨再生(GBR),当与骨移植物联合使用时,尽管膜降解会导致气体积聚,但仍能提高其性能。关于mg基膜在GBR中的应用及其对骨形成的影响的数据有限。
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引用次数: 0
Correction to “Reconstructive Therapy of Peri-Implantitis Following Non-Surgical Treatment: A Randomized Controlled Trial” 对“非手术治疗后种植体周围炎的重建治疗:一项随机对照试验”的更正
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-05 DOI: 10.1111/cid.70058

Soldini, M.C., R. Pons, J. Nart, A. Monje, N. Carrió, and C. Valles, “Reconstructive Therapy of Peri-Implantitis Following Non-Surgical Treatment: A Randomized Controlled Trial,” Clinical Implant Dentistry and Related Research 27 (2025): e70024, 10.1111/cid.70024

In page 13 of the published article in the Acknowledgements section, the original Acknowledgements was inadvertently omitted in the final submission.

The text “The authors acknowledge Dr. Cristina Esquinas for her support during data analysis. The study was self-funded. Xenografts and barrier membranes were donated by Straumann,” was incomplete. This should have read: “This work was supported, in part, by 2021 SGR 00626 (Generalitat de Catalunya), SCOI—Study and Control of Oral Infections, Universitat Internacional de Catalunya. The authors acknowledge Dr. Cristina Esquinas for her support during data analysis. The study was self-funded. Xenografts and barrier membranes were donated by Straumann.”

We apologize for this error.

苏尔尼,M.C., R. Pons, J. Nart, A. Monje, N. Carrió, C. Valles,“种植体周围炎非手术治疗后的重建治疗:一项随机对照试验”,临床种植牙医学与相关研究27 (2025):e70024, 10.1111/cid。70024在已发表文章的第13页的致谢部分,原始的致谢在最终提交中被无意中省略了。文中写道:“作者感谢Cristina Esquinas博士在数据分析过程中的支持。这项研究是自费的。异种移植物和屏障膜由Straumann捐赠,“不完整”。这应该是:“这项工作得到了2021年SGR 00626(加泰罗尼亚Generalitat de Catalunya), scoi -口腔感染研究和控制,加泰罗尼亚国际大学的部分支持。作者感谢Cristina Esquinas博士在数据分析过程中的支持。这项研究是自费的。异种移植物和屏障膜由斯特劳曼捐赠。”我们为这个错误道歉。
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引用次数: 0
Application of Biologics in Maxillary Sinus Augmentation Surgery: A Narrative Review 生物制剂在上颌窦隆胸手术中的应用综述
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-05 DOI: 10.1111/cid.70004
Tara Aghaloo, Pascal Valentini, Reule Yardley, Homayoun H. Zadeh

Maxillary sinus floor augmentation (MSFA) is one of the most predictable hard tissue augmentation procedures performed to support long-term dental implant survival and success. However, risks and complications still exist with this procedure including pain, bleeding, infection, oroantral communication, and inadequate bone regeneration for implant placement. To decrease some of these potential complications and improve outcomes, biologics are becoming more widely used in maxillary sinus augmentation. Autologous blood concentrates (ABCs) can be utilized as a membrane to seal a sinus membrane perforation or as “sticky bone” to mix with particulate material to make a congealed bone graft that will stay in place and be less likely to migrate from the site of placement or into the sinus cavity. Although the data is heterogeneous and somewhat conflicting, there is some evidence to support the use of ABCs for bone graft consolidation and overall wound healing due to the growth factors contained in the ABC. In addition, clotting factors in the plasma aid in hemostasis, which is an essential first step in the wound healing cascade. Individual growth factors such as rhBMP-2 and rhPDGF-BB are also clinically available for use in bone grafting procedures such as MSFA. rhBMP-2 is FDA approved for maxillary sinus augmentation, and clinical trials demonstrate de novo bone formation to facilitate dental implant placement. However, studies do not show a significant improvement over autogenous bone or bone substitutes such as xenograft or allografts. rhPDGF-BB has limited studies in this area, but may decrease residual particulate graft material and aid in increasing vital bone when bone substitutes are used. However, the use for MSFA is “off label” and few studies are available. Finally, enamel matrix derivative (EMD) has no data, and therefore, limited use for MFSA.

上颌窦底增强术(MSFA)是最可预测的硬组织增强术之一,用于支持种植体的长期存活和成功。然而,这种手术的风险和并发症仍然存在,包括疼痛、出血、感染、口窦沟通和种植体植入时骨再生不足。为了减少这些潜在的并发症,提高治疗效果,生物制剂在上颌窦隆胸术中的应用越来越广泛。自体血浓缩物(abc)可以用作封闭窦膜穿孔的膜,也可以用作“粘骨”,与颗粒材料混合制成凝固的骨移植物,这种移植物将保持在原位,不太可能从放置部位迁移或进入窦腔。尽管数据不一致且有些矛盾,但由于ABC中含有生长因子,有一些证据支持ABC用于植骨巩固和整体伤口愈合。此外,血浆中的凝血因子有助于止血,这是伤口愈合级联过程中必不可少的第一步。个体生长因子如rhBMP-2和rhPDGF-BB也可用于临床植骨手术,如MSFA。rhBMP-2被FDA批准用于上颌窦增强,临床试验证明新生骨形成有助于牙种植体的放置。然而,研究并没有显示自体骨或骨替代物(如异种或同种异体移植)的显著改善。rhPDGF-BB在这方面的研究有限,但当使用骨替代品时,可能会减少残留颗粒移植物材料并有助于增加重要骨。然而,MSFA的使用是“标签外的”,很少有研究可用。最后,牙釉质基质衍生物(EMD)没有数据,因此限制了MFSA的使用。
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引用次数: 0
In Vitro Analysis of Structural Integrity and Surface Alterations of Reused Healing Abutments 重复使用修复基台结构完整性及表面变化的体外分析
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-06-04 DOI: 10.1111/cid.70064
Won-Woo Lee, Jong-Hun Jun, Jeong-Hun Lee, Soorack Ryu, Kyung-Gyun Hwang, Chang-Joo Park

Purpose

This study aimed to investigate the changes in healing abutments (HAs) after use based on an in vitro comparison with unused HAs and to evaluate the effectiveness and clinical implications of reusing HAs.

Materials and Methods

Fifty used HAs were collected from affiliated clinics of the Department of Dentistry at Hanyang University Hospital and analyzed for surface damage, protein contamination, and microgap formation using three-dimensional laser microscopy and microcomputed tomography. The interfacial microgap between the implant and the abutment was measured at different tightening torques (5 N·cm, 10 N·cm, and 15 N·cm). Additionally, bacterial leakage and growth at various tightening torques were assessed by incubating reused HAs over different time periods.

Results

Reused HAs exhibited significant surface roughness, protein contamination, and larger microgap compared to unused HAs. The average microgap for reused HAs was 43 μm, whereas unused HAs showed no detectable gap. Bacterial leakage was significantly higher with reused HAs, particularly in those subjected to more than two tightening cycles. Tightening torques of 15 N·cm effectively eliminated the microgap and minimized bacterial leakage, whereas lower torques (5 N·cm and 10 N·cm) resulted in considerable bacterial growth.

Conclusion

Reusing HAs increases the risk of surface damage, protein contamination, microgap formation, and bacterial leakage, potentially compromising implant treatment outcomes. Higher tightening torque, (15 N·cm) significantly reduces microgap and bacterial leakage at the implant - HA imterface. Clinicians are advised to limit the reuse of HAs. However, if reuse is necessary, an appropriate tightening torque should be applied following a careful assessment of the clinical conditions of each HA.

目的通过与未使用的牙基体进行体外比较,探讨牙基体使用后的愈合变化,评价牙基体重复使用的效果和临床意义。材料与方法从汉阳大学附属医院牙内科门诊收集50例使用过的ha,利用三维激光显微镜和微计算机断层扫描分析其表面损伤、蛋白质污染和微间隙形成情况。在不同的拧紧力矩(5 N·cm、10 N·cm和15 N·cm)下测量种植体与基牙界面的微间隙。此外,通过在不同时间内孵育重复使用的HAs,评估了细菌在不同拧紧扭矩下的泄漏和生长情况。结果与未使用的HAs相比,重复使用的HAs表现出明显的表面粗糙度、蛋白质污染和更大的微间隙。重复使用的HAs的平均微间隙为43 μm,而未使用的HAs则没有可检测到的间隙。重复使用的ha的细菌泄漏率明显更高,特别是那些经历两次以上拧紧循环的ha。15 N·cm的拧紧力矩可以有效消除微间隙,减少细菌泄漏,而较低的拧紧力矩(5 N·cm和10 N·cm)会导致大量细菌生长。结论重复使用HAs增加了种植体表面损伤、蛋白质污染、微间隙形成和细菌泄漏的风险,可能影响种植体的治疗效果。较高的拧紧扭矩(15 N·cm)可显著减少种植体- HA界面的微间隙和细菌泄漏。建议临床医生限制ha的重复使用。但是,如果需要重复使用,则应在仔细评估每个HA的临床情况后施加适当的拧紧扭矩。
{"title":"In Vitro Analysis of Structural Integrity and Surface Alterations of Reused Healing Abutments","authors":"Won-Woo Lee,&nbsp;Jong-Hun Jun,&nbsp;Jeong-Hun Lee,&nbsp;Soorack Ryu,&nbsp;Kyung-Gyun Hwang,&nbsp;Chang-Joo Park","doi":"10.1111/cid.70064","DOIUrl":"https://doi.org/10.1111/cid.70064","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This study aimed to investigate the changes in healing abutments (HAs) after use based on an in vitro comparison with unused HAs and to evaluate the effectiveness and clinical implications of reusing HAs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Fifty used HAs were collected from affiliated clinics of the Department of Dentistry at Hanyang University Hospital and analyzed for surface damage, protein contamination, and microgap formation using three-dimensional laser microscopy and microcomputed tomography. The interfacial microgap between the implant and the abutment was measured at different tightening torques (5 N·cm, 10 N·cm, and 15 N·cm). Additionally, bacterial leakage and growth at various tightening torques were assessed by incubating reused HAs over different time periods.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Reused HAs exhibited significant surface roughness, protein contamination, and larger microgap compared to unused HAs. The average microgap for reused HAs was 43 μm, whereas unused HAs showed no detectable gap. Bacterial leakage was significantly higher with reused HAs, particularly in those subjected to more than two tightening cycles. Tightening torques of 15 N·cm effectively eliminated the microgap and minimized bacterial leakage, whereas lower torques (5 N·cm and 10 N·cm) resulted in considerable bacterial growth.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Reusing HAs increases the risk of surface damage, protein contamination, microgap formation, and bacterial leakage, potentially compromising implant treatment outcomes. Higher tightening torque, (15 N·cm) significantly reduces microgap and bacterial leakage at the implant - HA imterface. Clinicians are advised to limit the reuse of HAs. However, if reuse is necessary, an appropriate tightening torque should be applied following a careful assessment of the clinical conditions of each HA.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144206790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-Reported Healing of Static Computer-Assisted Sinus Lateral Window Osteotomy: A Randomized Controlled Trial 患者报告的静态计算机辅助窦侧窗截骨术愈合:一项随机对照试验
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-31 DOI: 10.1111/cid.70057
Nattakarn Narongchai, Sirida Arunjaroensuk, Keskanya Subbalekha, Paksinee Kamolratanakul, Atiphan Pimkhaokham, Nikos Mattheos

Objective

The primary aim was to investigate differences in patient-reported healing outcomes between static computer-assisted sinus floor augmentation (SCA-SFA) and the conventional freehand approach (SFA).

Material and Methods

Patient-reported healing outcomes were recorded in visual analog scale (VAS) on days 1–7 and 14, and intra and postoperative complications were assessed on weeks 2 and 4 after surgery. Operation time and operators' assessment of efficacy for SCA-SFA utility were recorded. Independent t-tests and Chi-square exact tests were performed for statistical evaluation between groups.

Results

Forty patients underwent lateral sinus augmentation (20 freehand-SFA + 20 SCA-SFA). No statistically significant difference was found between the two groups with regard to PROMs and intra, postoperative complications, apart from a higher level of swelling for SCA-SFA patients on day 2 after surgery (p = 0.04). The use of SCA-SFA significantly reduced the time needed to conduct the window osteotomy (SFA 18.56 ± 12.17 min vs. SCA-SFA 11.43 ± 4.75 min; p = 0.022) and the total surgery duration (SFA 69.89 ± 20.08 min vs. SCA-SFA 56.24 ± 16.01 min; p = 0.023).

Conclusions

Within the limitations of the study, SCA-SFA should be preferred when the reduction of surgical time is a priority while the costs of the intervention do not play a major role, and the design of the surgical guide should strive for minimal invasiveness.

Clinical Trial Registry: TCTR20230427005

目的研究静态计算机辅助窦底增强术(SCA-SFA)和传统徒手入路(SFA)在患者报告的愈合结果上的差异。材料和方法采用视觉模拟评分法(VAS)记录患者术后1-7天和14天的愈合情况,并于术后2周和4周评估手术内和术后并发症。记录手术时间和操作者对SCA-SFA效用的疗效评价。组间统计学评价采用独立t检验和卡方精确检验。结果40例患者行外侧窦增强术(20例徒手sfa + 20例SCA-SFA)。除了术后第2天SCA-SFA患者肿胀程度较高外,两组患者在PROMs及术后并发症方面无统计学差异(p = 0.04)。使用SCA-SFA可显著缩短窗切骨时间(SFA 18.56±12.17 min vs SCA-SFA 11.43±4.75 min);p = 0.022)和总手术时间(SFA组69.89±20.08 min vs. SCA-SFA组56.24±16.01 min;p = 0.023)。结论在本研究范围内,当以缩短手术时间为首要目标,干预费用不占主要地位,且手术指南设计应以微创为目标时,应优先选择SCA-SFA。临床试验注册:TCTR20230427005
{"title":"Patient-Reported Healing of Static Computer-Assisted Sinus Lateral Window Osteotomy: A Randomized Controlled Trial","authors":"Nattakarn Narongchai,&nbsp;Sirida Arunjaroensuk,&nbsp;Keskanya Subbalekha,&nbsp;Paksinee Kamolratanakul,&nbsp;Atiphan Pimkhaokham,&nbsp;Nikos Mattheos","doi":"10.1111/cid.70057","DOIUrl":"https://doi.org/10.1111/cid.70057","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The primary aim was to investigate differences in patient-reported healing outcomes between static computer-assisted sinus floor augmentation (SCA-SFA) and the conventional freehand approach (SFA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Patient-reported healing outcomes were recorded in visual analog scale (VAS) on days 1–7 and 14, and intra and postoperative complications were assessed on weeks 2 and 4 after surgery. Operation time and operators' assessment of efficacy for SCA-SFA utility were recorded. Independent t-tests and Chi-square exact tests were performed for statistical evaluation between groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty patients underwent lateral sinus augmentation (20 freehand-SFA + 20 SCA-SFA). No statistically significant difference was found between the two groups with regard to PROMs and intra, postoperative complications, apart from a higher level of swelling for SCA-SFA patients on day 2 after surgery (<i>p</i> = 0.04). The use of SCA-SFA significantly reduced the time needed to conduct the window osteotomy (SFA 18.56 ± 12.17 min vs. SCA-SFA 11.43 ± 4.75 min; <i>p</i> = 0.022) and the total surgery duration (SFA 69.89 ± 20.08 min vs. SCA-SFA 56.24 ± 16.01 min; <i>p</i> = 0.023).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Within the limitations of the study, SCA-SFA should be preferred when the reduction of surgical time is a priority while the costs of the intervention do not play a major role, and the design of the surgical guide should strive for minimal invasiveness.</p>\u0000 \u0000 <p><b>Clinical Trial Registry:</b> TCTR20230427005</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Clinical Implant Dentistry and Related Research
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