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Changes in Cigarette Availability and Sales Associated with California's Statewide Flavored Tobacco Sales Restriction: A Synthetic Control Analysis. 卷烟的可得性和销售变化与加州全州风味烟草销售限制有关:一项综合控制分析。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-21 DOI: 10.1016/j.amepre.2026.108286
Morgan A Whitney, Doris G Gammon, James Nonnemaker, Lisa Henriksen, Elizabeth Andersen-Rodgers, Rafael Colonna, Todd Rogers

Introduction: California enacted a statewide restriction on flavored tobacco product sales on December 21, 2022. Policy efforts to eliminate flavored tobacco products from retail environments are designed to restrict consumer access, with the goal of reducing initiation and experimentation, and supporting cessation.

Methods: This study used NielsenIQ retail scanner data to study cigarette pack sales and availability (i.e., the weekly number of universal product codes (UPCs) with positive sales), pre-intervention (1/1/2021 to 12/17/2022) to post-intervention (12/18/2022 to 12/30/2023) overall and by flavor category: tobacco/unflavored, menthol, and "nonmenthol" labeled. A control method was employed to create a synthetic California, based on pre-intervention-period data, to compare to California, post-intervention.

Results: From pre- to post-intervention, average weekly availability of menthol cigarettes decreased 44% in California, with ∼175 products still available in December 2023; sales decreased by 90%. "Non-menthol" labeled cigarette availability increased 194% and sales increased 708%. Total cigarette availability in California decreased, but total sales were unchanged. Changes in California were distinct from synthetic California.

Conclusions: California's statewide flavored tobacco sales restriction was effective at reducing the availability and sale of menthol cigarettes despite the increase in availability and sales of "non-menthol" labeled cigarettes. Total cigarette sales remain unchanged in the oneyear post-intervention due to the increase in sales of "non-menthol" labeled cigarettes.

导言:加州于2022年12月21日在全州范围内实施了调味烟草产品销售限制。从零售环境中消除加味烟草制品的政策努力旨在限制消费者获取,目的是减少初次接触和试验,并支持戒烟。方法:本研究使用NielsenIQ零售扫描仪数据研究卷烟包装销售和可用性(即每周销售的通用产品代码(upc)的数量),干预前(2021年1月1日至2022年12月17日)至干预后(2022年12月18日至2023年12月30日)的整体和风味类别:烟草/无香料,薄荷醇和“非薄荷醇”标签。采用对照方法,根据干预前的数据创建一个合成的加州,与干预后的加州进行比较。结果:从干预前到干预后,加州薄荷香烟的平均每周供应量下降了44%,到2023年12月仍有175种产品可用;销售额下降了90%。贴有“非薄荷醇”标签的香烟供应量增加了194%,销量增加了708%。加州的香烟总供应量下降了,但总销售额没有变化。加州的变化不同于人工合成的加州。结论:尽管“非薄荷醇”标签香烟的可得性和销量有所增加,但加州全州范围内的调味烟草销售限制在减少薄荷醇香烟的可得性和销量方面是有效的。由于“非薄荷醇”标签香烟的销量增加,在干预后的一年内,香烟总销量保持不变。
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引用次数: 0
Promoting Preventive Medicine: Increasing Specialty Awareness, Knowledge and Interest through Peer-to-Peer Education and Engagement. 促进预防医学:通过点对点教育和参与提高专业意识、知识和兴趣。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-21 DOI: 10.1016/j.amepre.2026.108287
Marissa Khajavi, Minahil Cheema, Jennifer Paul-Quinn

Medical students often lack sufficient awareness and understanding of preventive medicine. Students acknowledge the importance of training in prevention and public health, but there is low awareness of the specialty, with few medical students considering it as a career path. This study aimed to assess the lack of awareness and understanding of the specialty of Public Health and General PH/GPM (PH/GPM) among medical students as well as increase the number of students considering a career in the specialty. Participants completed a pre-survey that assessed their current awareness, knowledge, and interest of the PH/GPM specialty. The intervention consisted of distributing the American College Prevention Medicine (ACPM) toolkit, video, and flyers, and a Q&A. A post-survey assessed changes and elicited the most appealing learning method. The study population included all medical students at the University of Maryland. The data was collected and analyzed in 2024. Pre- and post-survey responses were compared using chi-square tests. All three outcomes (awareness, knowledge, and interest) improved significantly from pre (n=430) to post-survey (n=390). Awareness increased from 48% to 100% (p<0.0001), knowledge increased from 18% to 96% (p<0.0001) and interest increased from 10% to 67% (p<0.0001). Flyers were identified as the most appealing method (see Figure 1.) of information delivery (71% of respondents), followed by the ACPM toolkit (25%), and ACPM video (4%). There is an opportunity in medical schools to provide targeted education to increase medical students' awareness, understanding, and interest in the specialty. PH/GPM remains under-recognized and under-promoted in medical schools. Educational outreach in medical schools may increase the number of future doctors pursuing careers in PH/GPM.

医学生对预防医学的认识和理解往往不足。学生们承认预防和公共卫生培训的重要性,但对该专业的认识很低,很少有医科学生将其作为职业道路。本研究旨在评估医学生对公共卫生和一般PH/GPM (PH/GPM)专业缺乏认识和理解的情况,并增加考虑在该专业工作的学生人数。参与者完成了一项预调查,评估了他们目前对PH/GPM专业的认识、知识和兴趣。干预包括分发美国大学预防医学(ACPM)工具包、视频、传单和问答。一项事后调查评估了变化,并得出了最吸引人的学习方法。研究对象包括马里兰大学的所有医学院学生。数据是在2024年收集和分析的。使用卡方检验比较调查前后的反应。从调查前(n=430)到调查后(n=390),所有三个结果(意识、知识和兴趣)都有显著改善。意识从48%增加到100% (p
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引用次数: 0
State cannabis and alcohol policy environments: Associations with college students' use of cannabis, alcohol and both substances. 国家大麻和酒精政策环境:与大学生使用大麻、酒精和这两种物质的关系。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-21 DOI: 10.1016/j.amepre.2026.108275
David C R Kerr, Harold Bae, Timothy S Naimi, Meenakshi S Subbaraman, Haley M Hummel, Marlene C Lira

Introduction: Cannabis policies differ between states that have legalized cannabis use, and within states over time following legalization milestones. A continuous measure of state cannabis policy environments was examined in relation to college students' cannabis and alcohol use, accounting for concurrent state alcohol policies.

Methods: Undergraduates (n=902,486) ages 18-24 years from 591 four-year institutions in 47 states completed a cross-sectional survey between 2008 and 2019. Time-varying, state-level Cannabis Policy Scale (CPS) and Alcohol Policy Scale (APS) scores were sums of 17 and 29 policies, respectively, weighted by efficacy and state-level implementation. Outcomes were any 30-day use and frequent use (20+ days) of cannabis and alcohol, 2-week binge drinking (5+ drinks in a sitting), and co-use (binge drinking and frequent cannabis use). Data were analyzed in 2024-2025.

Results: Higher CPS scores (greater restrictiveness) were associated with significantly lower odds of cannabis use, frequent cannabis use, and co-use [OR=0.97 (0.96-0.98); 0.93 (0.91-0.94); and 0.94 (0.92-0.96), respectively], but not significantly associated with alcohol use outcomes. Higher APS scores were significantly associated with lower odds of every cannabis, alcohol, and co-use outcome. CPS and APS effects generally were significant for underage students (ages 18-20), but stronger for older students (ages 21-24).

Conclusions: Under less restrictive state cannabis and alcohol policy regimes college students were more apt to use cannabis and alcohol frequently and concurrently. To improve students' well-being, campus- and community-level policymakers can build on strong state policy environments or compensate for weak ones, using APS and CPS as tools to identify these needs.

大麻政策在大麻使用合法化的州之间有所不同,在合法化里程碑之后的一段时间内也有所不同。考虑到同时实施的州酒精政策,对与大学生大麻和酒精使用有关的州大麻政策环境进行了连续测量。方法:来自47个州591所四年制大学的18-24岁的本科生(n= 902486)在2008年至2019年期间完成了一项横断面调查。时变的国家级大麻政策量表(CPS)和酒精政策量表(APS)得分分别是17项和29项政策的总和,按效力和国家级执行情况加权。结果是任何30天使用和频繁使用大麻和酒精(20天以上),2周酗酒(一次喝5杯以上)和共同使用(酗酒和频繁使用大麻)。数据分析时间为2024-2025年。结果:较高的CPS评分(更大的限制性)与大麻使用、频繁使用和共同使用的几率显著降低相关[OR=0.97 (0.96-0.98);0.93 (0.91 - -0.94);和0.94(分别为0.92-0.96)],但与酒精使用结果无显著相关。较高的APS评分与较低的大麻、酒精和共同使用结果的几率显著相关。CPS和APS对未成年学生(18-20岁)的影响普遍显著,但对年龄较大的学生(21-24岁)的影响更强。结论:在限制较少的州大麻和酒精政策制度下,大学生更倾向于频繁和同时使用大麻和酒精。为了改善学生的福祉,校园和社区层面的政策制定者可以利用APS和CPS作为确定这些需求的工具,以强大的国家政策环境为基础,或弥补薄弱的国家政策环境。
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引用次数: 0
The impact of restaurant menu eco labels on consumer meal selections: a randomized controlled trial. 餐馆菜单生态标签对消费者膳食选择的影响:一项随机对照试验。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-09 DOI: 10.1016/j.amepre.2026.108265
Alexandria E Reimold, Jennifer Falbe, Brent F Kim, Aviva A Musicus, Nina Carr, Raychel Santo, Clara Cho, Cindy W Leung, Christina A Roberto, Julia A Wolfson

Introduction: Food systems account for ∼30% of the greenhouse gas emissions (GHGE) that contribute to climate change. Climate labels on restaurant menus may help consumers decrease their food-related climate impact and improve meal nutrition given that environmentally sustainable diets are also healthier. This study evaluated the degree to which different climate labels promoted healthier and lower climate impact food choices.

Study design: Online RCT conducted in 2024, analyzed in 2025.

Setting/participants: A national sample of 6,221 adults benchmarked to the US Census on sex, race, ethnicity, and age.

Intervention: Participants were randomized to view a fast-food menu with either a control label or one of four climate label designs: (1) Numeric; (2) Climate Grade; (3) Traffic Light; or (4) Warning. Labels appeared alongside main menu items and were based on total supply chain GHGE associated with each item. Participants were instructed to select a hypothetical lunch meal order.

Main outcome measures: The main outcomes of this study were the selected meals' nutritional quality (measured using a modified Nutrient Profile Index [NPI] score) and GHGE in kgCO2e per meal.

Results: Compared with participants in the control condition (mean NPI score=50.6, SE(0.28)), those in the Traffic Light (mean NPI score=51.3, SE(0.28); p=0.013) and Warning (mean NPI score=51.3, SE(0.28); p=0.015) label groups chose significantly healthier meals (i.e., higher NPI score). Compared to the control (mean GHGE=27.5, SE(0.97)), all climate labels resulted in meals with significantly lower GHGE. Participants in the Traffic Light condition selected meals with the lowest GHGE (mean GHGE=22.6, SE(0.97); p<0.001), followed by Warning (mean GHGE=23.9, SE(0.97); p<0.001), Grade (mean GHGE=24.6, SE(0.97); p=0.004), and Numeric (mean GHGE=24.7, SE(0.98); p=0.005).

Conclusions: Interpretive climate labels, particularly Traffic Light and Warning label designs, are a promising way of improving the nutritional quality while reducing the climate impact of restaurant meal orders.

Trial registration: (https://clinicaltrials.gov/study/NCT06909019).

导言:粮食系统占导致气候变化的温室气体排放(GHGE)的30%。餐馆菜单上的气候标签可以帮助消费者减少与食物有关的气候影响,并改善膳食营养,因为环境可持续的饮食也更健康。本研究评估了不同气候标签促进更健康和低气候影响食品选择的程度。研究设计:在线RCT于2024年进行,2025年进行分析。背景/参与者:6221名成年人的全国样本,以美国人口普查的性别、种族、民族和年龄为基准。干预:参与者被随机分配观看快餐菜单,菜单上有对照标签或四种气候标签设计中的一种:(1)数字标签;(2)气候等级;(3)红绿灯;(4)警告。标签出现在主菜单项目旁边,并基于与每个项目相关的供应链温室气体排放总量。参与者被要求选择一种假设的午餐顺序。主要结果测量:本研究的主要结果是所选膳食的营养质量(使用改进的营养概况指数[NPI]评分来测量)和每餐温室气体排放量(每公斤二氧化碳当量)。结果:与对照组(平均NPI得分=50.6,SE(0.28))相比,红绿灯组(平均NPI得分=51.3,SE(0.28));p=0.013)和Warning(平均NPI评分=51.3,SE(0.28);p=0.015)标签组显著选择更健康的膳食(即更高的NPI评分)。与对照组(平均GHGE=27.5,标准差(0.97))相比,所有气候标签导致的膳食GHGE显著降低。红绿灯组选择GHGE最低的食物(平均GHGE=22.6, SE(0.97));结论:解释性气候标签,特别是交通灯和警告标签设计,是一种很有前途的方法,可以提高营养质量,同时减少餐馆用餐订单对气候的影响。试验注册:(https://clinicaltrials.gov/study/NCT06909019)。
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引用次数: 0
Trends in Sodium Content of Meat-Based Versus Meat-Free Menu Items in 75 Large Chain Restaurants in the U.S., 2013-2021. 2013-2021年美国75家大型连锁餐厅肉类与无肉菜单中钠含量的趋势
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-09 DOI: 10.1016/j.amepre.2026.108264
Anna C Tucker, Megan P Mueller, Lindsey Smith Taillie, Jason P Block, Cindy W Leung, Julia A Wolfson

Introduction: Reducing meat intake could improve planetary and human health, but high sodium in commercially prepared meat-free foods may undermine some health benefits of reducing meat intake. This study characterized trends in sodium content of meat-based versus meat-free foods in large chain U.S. restaurants and examined mean sodium differences and portions of items qualifying for a high-in-sodium warning label.

Methods: Data came from MenuStat.org, a longitudinal database of menu items from U.S. restaurants collected annually from 2013 to 2021. The analytic sample included 24,147 items from 75 restaurants. Linear regression for panel data assessed trends in mean per-item sodium overall and by meat category (meat based/meat free), adjusted for restaurant type, menu category, children's item, and energy. Postestimation margins estimated mean sodium. Analyses were conducted in 2025.

Results: From 2013 to 2021, mean sodium content was high, with no significant changes among meat-based or meat-free items. Meat-free items accounted for 22.1% of items and had lower mean sodium than meat-based items (-301 mg; 95% CI= -365, -238), consistent over time, across restaurant types and nearly all menu categories. Across all years, 13.4%-17.2% meat-based and 3.7%-5.9% of meat-free items would qualify for a high-in-sodium warning label by exceeding 100% of the sodium Daily Value.

Conclusions: Across 75 large chain restaurants, the sodium content of menu items did not change from 2013 to 2021. Meat-free items were lower in mean sodium than meat-based items but were still high in sodium. Efforts to shift toward plant-forward diets should be paired with stronger sodium reduction policies.

引言:减少肉类摄入可以改善地球和人类的健康,但商业制备的无肉食品中的高钠可能会破坏减少肉类摄入的一些健康益处。这项研究描述了美国大型连锁餐厅中肉类食品与无肉食品钠含量的趋势,并检查了平均钠含量的差异和符合“高钠”警告标签的食品的部分。方法:数据来自MenuStat.org,这是一个从2013-2021年每年收集的美国餐馆菜单项目的纵向数据库。分析样本包括来自75家餐馆的24147件物品。面板数据的线性回归评估了总体和肉类类别(含肉/无肉)平均每项钠的趋势,并根据餐厅类型、菜单类别、儿童项目和能量进行了调整。估计后边际估计平均钠。分析在2025年进行。结果:从2013-2021年,平均钠含量很高,在肉类和无肉类食品中没有显著变化。无肉食品占22.1%,平均钠含量低于肉类食品(-301毫克;95% CI: -365, -238),随着时间的推移,几乎所有餐厅类型和菜单类别都是一致的。在所有年份中,13.4-17.2%的肉类食品和3.7-5.9%的无肉食品如果超过每日钠摄入量的100%,就有资格贴上“高钠”的警告标签。结论:在75家大型连锁餐厅中,菜单项目的钠含量从2013年到2021年没有变化。无肉食品的平均钠含量低于含肉食品,但钠含量仍然很高。向植物性饮食转变的努力应该与更强有力的钠减少政策相结合。
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引用次数: 0
Household Debt and the 10 Leading Causes of US Death. 家庭债务和美国人死亡的十大主要原因。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-07 DOI: 10.1016/j.amepre.2026.108261
Emilie Bruzelius, Katrina L Kezios
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引用次数: 0
The Impact of a Student-Led Initiative to Improve Cancer Screenings in Primary Care. 以学生为主导的倡议对改善初级保健癌症筛查的影响。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-07 DOI: 10.1016/j.amepre.2026.108262
Katherine V Klein, Priya V Srivastava, John M Sauer, Nirali Trivedi, Sahiba K Gill, Fadia Barakzai, Yeonwoo J Sim, Matthew B Green, Philip Collins, Anne C Jones

System-level interventions are needed to improve early breast cancer detection and prevent colon and cervical cancers owing to suboptimal adherence to screening guidelines in the U.S. A student-led outreach initiative was conducted at a New Jersey family medicine practice to improve screening rates among overdue patients. From January 1, 2023 to February 1, 2025, an interventional cohort study identified 911 patients aged 21-80 years through electronic health record review, of whom 822 were confirmed to be overdue and eligible for outreach. The primary outcome was completion of guideline-recommended screenings within 2 years. Thirty-three students contacted 822 patients who were overdue for cancer screening (mean age of 61 years; 74% female; 63% White, 16% Black, 3% Hispanic, 3% Asian), representing 1,365 overdue tests. Successful contact was made with 386 patients (47%), of whom 53 (13.7%) reported being up to date, verified when possible. The screening status of the 436 uncontacted patients was unknown, so all 822 were retained in the denominator to avoid overestimating intervention effects. Outreach generated an 11.4% referral rate (156 of 1,365), including 47 colonoscopies, 39 Cologuard, 48 mammograms, and 22 Pap smears. Completion rates were 5.5% for colon cancer (35 of 636), 6.7% for breast cancer (27 of 402), and 3.1% for cervical cancer (10 of 327). Abnormal findings occurred in 57.9% of colonoscopies, 18.7% of Cologuard tests, 33.3% of mammograms, and 0% of Pap smears. This student-led outreach to patients overdue for cancer screenings facilitated referrals for colorectal, breast, and cervical cancer; supported early detection of abnormalities; and provided students with hands-on experience in preventive medicine, fostering development as community-focused physicians.

在美国,由于筛查指南的依从性不佳,需要系统层面的干预措施来改善早期乳腺癌的检测,并预防结肠癌和宫颈癌。新泽西州的一家家庭医学诊所开展了一项由学生主导的推广活动,以提高逾期患者的筛查率。从2023年1月1日至2025年2月1日,一项介入队列研究通过电子健康记录审查确定了911例年龄在21-80岁之间的患者,其中822例被确认过期并有资格进行外展。主要结局是在两年内完成指南推荐的筛查。33名学生联系了822名逾期癌症筛查的患者(平均年龄61岁,女性占74%,白人占63%,黑人占16%,西班牙裔占3%,亚裔占3%),共计1365例逾期检查。成功接触了386例(47%)患者,其中53例(13.7%)报告了最新情况,并在可能时进行了核实。436名未接触患者的筛查情况未知,为避免高估干预效果,将822名患者全部保留在分母中。外展产生了11.4%的转诊率(1365例中的156例),包括47例结肠镜检查、39例Cologuard®、48例乳房x光检查和22例巴氏涂片检查。结肠癌的完成率为5.5%(35/636),乳腺癌为6.7%(27/402),宫颈癌为3.1%(10/327)。57.9%的结肠镜检查、18.7%的Cologuard检查、33.3%的乳房x光检查和0%的巴氏涂片检查出现异常。该项目由学生主导,面向逾期未做癌症筛查的患者,促进了结直肠癌、乳腺癌和宫颈癌的转诊,支持了异常的早期发现,并为学生提供了预防医学的实践经验,促进了他们成为以社区为中心的医生。
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引用次数: 0
Language Barriers as a Driver of Health Disparity in Bone Density Screening Among the Aging Population. 老龄人口骨密度筛查中语言障碍对健康差异的影响
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-06 DOI: 10.1016/j.amepre.2026.108263
Tanner B Heaton, Nathan F Behrens, J B Eyring, Jeremy M Gililland, Christopher E Pelt, Amy M Cizik

Introduction: Osteoporosis widely affects the aging population and often leads to debilitating fragility fractures. Dual-energy X-ray absorptiometry (DXA) scans are important for osteoporosis screening and treatment among aging women to prevent fragility fractures; however, disparities exist across populations. This study analyzed these disparities to help reduce screening inequalities to prevent complications of osteoporosis.

Methods: A sample was used from the 2018, 2020, and 2022 U.S. Medical Expenditure Panel Survey of women who responded about screening DXA utilization. Logistic regression modeling was used to determine associations between social determinants of health (SDOH), particularly between limited English proficiency (LEP), and screening DXA utilization. Two models, SDOH and SDOH+LEP, were generated utilizing these variables modified by the addition of the variable of English proficiency.

Results: Half of the 10,079 respondents without osteoporosis (48%, N=4,851) reported undergoing a DXA scan with a median age of 69 years (50-85). Low income; lower education; Black, Asian, Hispanic race/ethnicity; and LEP were significantly associated with not receiving a screening DXA scan. Hispanic women had a 55% decreased likelihood of receiving a screening DXA scan (OR=0.450, 95%CI: 0.365-0.554, p<0.001) compared to non-Hispanic White women, though this lost statistical significance when accounting for LEP (OR=0.732, 95%CI: 0.521-1.029, p=0.073).

Conclusions: The results demonstrate significant SDOH disparities in DXA screening for osteoporosis. The effect is modified, specifically the association of race/ethnicity, when LEP is included as a risk factor. Awareness of these disparities is important for primary care and other providers to deliver equitable prevention and treatment opportunities for osteoporosis.

骨质疏松症广泛影响老年人,并经常导致衰弱性脆性骨折。双能x线吸收仪(DXA)扫描对老年妇女骨质疏松症筛查和治疗预防脆性骨折很重要;然而,不同人群之间存在差异。本研究分析了这些差异,以帮助减少筛查不平等,预防骨质疏松症并发症。方法:使用2018年、2020年和2022年美国医疗支出小组调查中回应DXA筛查使用情况的女性样本。使用逻辑回归模型来确定健康的社会决定因素(SDOH)之间的关系,特别是有限的英语熟练程度(LEP)与筛选DXA利用之间的关系。在这些变量的基础上加入英语水平变量,生成SDOH和SDOH+LEP两个模型。结果:10,079名无骨质疏松症的应答者中有一半(48%,N=4,851)接受了DXA扫描,中位年龄为69岁(50-85岁)。较低的收入;受教育程度较低;黑人、亚洲人、西班牙人;LEP与未接受筛查性DXA扫描显著相关。西班牙裔女性接受DXA扫描筛查的可能性降低55% (OR=0.450, 95%CI: 0.365-0.554)。结论:结果显示骨质疏松症DXA筛查中存在显著的SDOH差异。当LEP被列为一个风险因素时,这种影响被修正,特别是与种族/民族的联系。认识到这些差异对于初级保健和其他提供者提供公平的骨质疏松症预防和治疗机会非常重要。
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引用次数: 0
The Impact of Recreational Cannabis Legalization on Cannabis Use in U.S. Adults From 2016 to 2023: A Quasi-Experimental Study. 2016 - 2023年娱乐性大麻合法化对美国成年人大麻使用的影响:一项准实验研究。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-06 DOI: 10.1016/j.amepre.2025.108221
Summer Sherburne Hawkins, Christopher E Baidoo, Rebekah Levine Coley, Ryan S Centanni, Christopher F Baum

Introduction: Although cannabis use has increased during a time of expanding cannabis legalization, there is limited evidence on how use has shifted in response to legalization across at-risk groups. This study examined the impact of recreational cannabis legalization on adult cannabis use overall and by demographic and higher-risk strata.

Methods: Behavioral Risk Factor Surveillance System 2016-2023 surveys (N=859,600 adults from 38 states) were linked to state recreational cannabis legalization. Using quasi-experimental difference-in-differences zero-inflated negative binomial and probit regressions, the impact of legalization on cannabis use was examined overall and by demographic (age, sex, education, race/ethnicity) and higher-risk (mental health, cigarette smoking, alcohol use) strata, adjusting for demographic and policy controls, state, and year. Data were compiled in 2024-2025 and analyzed in 2025.

Results: Recreational cannabis legalization was associated with 44% lower odds of zero cannabis use (95% CI=40%, 48%), indicating higher likelihood of any use, not with a greater frequency of use among users, and a significant total effect estimate, indicating higher cannabis use after legalization. When cannabis use was dichotomized, legalization was associated with a 0.94 percentage point increase in the likelihood of use (95% CI=0.04, 1.84), a 9.8% relative increase compared with 2016 levels. Adults aged ≥60 years, female, White, or college educated had generally lower cannabis use, yet significant interactions (all p<0.1) revealed that they were the most responsive to legalization, with 1-2 percentage point increases in use.

Conclusions: Recreational cannabis legalization is driving increases in cannabis use among groups with historically lower use rather than increasing use among those who already used cannabis.

导言:虽然大麻的使用在扩大大麻合法化的时期有所增加,但关于在高危群体中大麻的使用如何随着合法化而发生变化的证据有限。这项研究调查了娱乐性大麻合法化对成人大麻使用的总体影响,并按人口和高风险阶层进行了调查。方法:行为风险因素监测系统2016-2023年调查(N=859,600名来自38个州的成年人)与州娱乐性大麻合法化有关。采用准实验差异中的差异零膨胀负二项回归和概率回归,对大麻使用合法化的影响进行了总体和按人口(年龄、性别、教育程度、种族/族裔)和高风险(心理健康、吸烟、饮酒)阶层的审查,并根据人口和政策控制、州和年份进行了调整。数据汇编于2024-2025年,并于2025年进行分析。结果:休闲大麻合法化与零大麻使用的几率降低44%相关(95% CI=40%, 48%),这表明使用大麻的可能性更高,但使用者使用大麻的频率不高,并且总效应估计显着,表明大麻合法化后大麻使用率更高。当大麻使用被一分为二时,合法化与使用可能性增加0.94个百分点相关(95% CI=0.04, 1.84),与2016年的水平相比,相对增加了9.8%。年龄≥60岁、女性、白人或受过大学教育的成年人的大麻使用量普遍较低,但存在显著的相互作用。结论:娱乐性大麻合法化导致大麻使用量在历史上较低的人群中增加,而不是在已经使用大麻的人群中增加。
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引用次数: 0
ASSOCIATION BETWEEN ULTRA-PROCESSED DIETARY PATTERN AND WEIGHT GAIN IN ADULTS: THE NUTRINET-BRASIL COHORT STUDY. 成人超加工饮食模式与体重增加之间的关系:营养-巴西队列研究
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-27 DOI: 10.1016/j.amepre.2025.108250
Maria Alvim Leite, Leandro F M Rezende, Eurídice Martínez Steele, Edward Giovannucci, Xuehong Zhang, Renata Bertazzi Levy

Introduction: Ultra-processed dietary patterns have been associated with higher risk of weight gain. Previous studies were conducted in high-income countries using dietary assessment tools not specifically designed to identify ultra-processed foods (UPF). The purpose of this study was to examine the prospective association between ultra-processed dietary pattern and risk of weight gain in Brazilian adults.

Methods: Data from 24,453 participants from NutriNet-Brasil cohort study who responded to two Nova24h dietary recalls at baseline and were followed for a median of 43.6 months were analyzed. Ultra-processed dietary pattern was assessed based on the contribution of UPF to total energy intake. Weight gain was defined as ≥5% and ≥10% increase from baseline body weight, based on self-reported measurements. Cox proportional hazards models and stratified analyses were performed.

Results: A linear dose-response association was observed: for each 10% increase in UPF contribution, the risk of ≥5% weight gain increased by 5% [10,092 cases, hazard ratio (HR) 1.05; 95% confidence interval (CI) 1.04 to 1.07] and the risk of ≥10% weight gain increased by 8% (4,865 cases, HR 1.08; 95% CI 1.06 to 1.10). Compared with participants in the lowest quintile (<11.8% of UPF), those in the highest quintile (≥34.0%) had higher risk of weight gain (≥5%: HR 1.23; 95% CI 1.15 to 1.31; ≥10%: HR 1.35; 95% CI 1.23 to 1.48). These associations persisted, although attenuated, after adjustment for diet nutritional profile.

Conclusions: Higher exposure to ultra-processed dietary pattern was associated with an increased risk of weight gain in Brazilian adults.

导读:过度加工的饮食模式与更高的体重增加风险有关。以前的研究是在高收入国家进行的,使用的饮食评估工具不是专门设计用于识别超加工食品(UPF)的。本研究的目的是研究巴西成年人超加工饮食模式与体重增加风险之间的潜在关联。方法:对来自NutriNet-Brasil队列研究的24,453名参与者的数据进行分析,这些参与者在基线时接受了两次nova24小时饮食召回,并进行了中位43.6个月的随访。根据UPF对总能量摄入的贡献来评估超加工饮食模式。体重增加的定义是根据自我报告的测量结果,从基线体重增加≥5%和≥10%。采用Cox比例风险模型并进行分层分析。结果:观察到线性剂量-反应关系:UPF贡献每增加10%,体重增加≥5%的风险增加5%[10,092例,危险比(HR) 1.05;95%可信区间(CI) 1.04 ~ 1.07],体重增加≥10%的风险增加8%(4865例,HR 1.08; 95% CI 1.06 ~ 1.10)。与最低五分之一的参与者相比(结论:高暴露于超加工饮食模式与巴西成年人体重增加的风险相关。
{"title":"ASSOCIATION BETWEEN ULTRA-PROCESSED DIETARY PATTERN AND WEIGHT GAIN IN ADULTS: THE NUTRINET-BRASIL COHORT STUDY.","authors":"Maria Alvim Leite, Leandro F M Rezende, Eurídice Martínez Steele, Edward Giovannucci, Xuehong Zhang, Renata Bertazzi Levy","doi":"10.1016/j.amepre.2025.108250","DOIUrl":"https://doi.org/10.1016/j.amepre.2025.108250","url":null,"abstract":"<p><strong>Introduction: </strong>Ultra-processed dietary patterns have been associated with higher risk of weight gain. Previous studies were conducted in high-income countries using dietary assessment tools not specifically designed to identify ultra-processed foods (UPF). The purpose of this study was to examine the prospective association between ultra-processed dietary pattern and risk of weight gain in Brazilian adults.</p><p><strong>Methods: </strong>Data from 24,453 participants from NutriNet-Brasil cohort study who responded to two Nova24h dietary recalls at baseline and were followed for a median of 43.6 months were analyzed. Ultra-processed dietary pattern was assessed based on the contribution of UPF to total energy intake. Weight gain was defined as ≥5% and ≥10% increase from baseline body weight, based on self-reported measurements. Cox proportional hazards models and stratified analyses were performed.</p><p><strong>Results: </strong>A linear dose-response association was observed: for each 10% increase in UPF contribution, the risk of ≥5% weight gain increased by 5% [10,092 cases, hazard ratio (HR) 1.05; 95% confidence interval (CI) 1.04 to 1.07] and the risk of ≥10% weight gain increased by 8% (4,865 cases, HR 1.08; 95% CI 1.06 to 1.10). Compared with participants in the lowest quintile (<11.8% of UPF), those in the highest quintile (≥34.0%) had higher risk of weight gain (≥5%: HR 1.23; 95% CI 1.15 to 1.31; ≥10%: HR 1.35; 95% CI 1.23 to 1.48). These associations persisted, although attenuated, after adjustment for diet nutritional profile.</p><p><strong>Conclusions: </strong>Higher exposure to ultra-processed dietary pattern was associated with an increased risk of weight gain in Brazilian adults.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108250"},"PeriodicalIF":4.5,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145858926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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American Journal of Preventive Medicine
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