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Exploring etiologic contributions to the occurrence of external apical root resorption 探索外根尖吸收的病因。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.05.017

Introduction

External apical root resorption (EARR) is often an undesirable sequela of orthodontic treatment. Prior studies have suggested a substantial link between EARR and certain genetic components. Single nucleotide polymorphisms (SNPs) may play a role as predisposing factors. This study aimed to investigate the potential association between EARR and various SNPs.

Methods

The study included 218 orthodontic participants of all malocclusions who had available pretreatment and posttreatment panoramic radiographs. The most severely affected maxillary incisor on the radiograph was assessed for EARR using a 0-4 categorical scale. DNA was taken from the saliva samples of the participants, and the SNPs were analyzed using polymerase chain reaction and TaqMan chemistry. Statistical testing was performed to verify any associations with EARR (P <0.05).

Results

From all genes tested, the rs678397 SNP of ACT3N (P = 0.003) and the rs1051771 SNP of TSC2 (P = 0.03) were significantly associated with EARR. No association could be established between other polymorphisms and EARR. In addition, patients with Class III malocclusion and extended treatment times were at increased risk of developing EARR.

Conclusions

Our results support the concept of gene polymorphisms as risk factors in EARR. In particular, a significant association was found between ACT3N and TSC2 and EARR. Clinically, predisposing risk factors for EARR should be assessed for each patient.
导言:外牙根尖吸收(EARR)通常是正畸治疗的不良后遗症。先前的研究表明,EARR 与某些遗传因素有很大的联系。单核苷酸多态性(SNPs)可能是诱发因素之一。本研究旨在调查 EARR 与各种 SNPs 之间的潜在关联:该研究纳入了 218 名有治疗前和治疗后全景照片的所有畸形正畸参与者。采用0-4分类量表对X光片上受影响最严重的上颌切牙进行EARR评估。从参与者的唾液样本中提取 DNA,使用聚合酶链反应和 TaqMan 化学方法分析 SNPs。通过统计检验来验证与 EARR 的关系(P 结果):在所有检测基因中,ACT3N 的 rs678397 SNP(P = 0.003)和 TSC2 的 rs1051771 SNP(P = 0.03)与 EARR 显著相关。其他多态性与 EARR 之间没有关联。此外,Ⅲ类错颌畸形和治疗时间延长的患者发生EARR的风险也更高:我们的研究结果支持基因多态性是 EARR 风险因素的概念。结论:我们的研究结果支持基因多态性是 EARR 风险因素的概念,尤其是 ACT3N 和 TSC2 与 EARR 之间存在明显关联。临床上,应针对每位患者评估其易患 EARR 的风险因素。
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引用次数: 0
Efficacy of planned moderate to severe torque changes in maxillary central incisors with the Invisalign appliance: A retrospective investigation 使用隐适美(Invisalign)矫正器对上颌中切牙进行计划性中度至重度扭力改变的效果:回顾性研究。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.06.008

Introduction

This study aimed to investigate whether there was a difference between the planned and achieved lingual root torque of the maxillary central incisors in patients treated with an initial series of Invisalign (Align Technology, Santa Clara, Calif) aligners in which >10° change in the inclination of these teeth was prescribed via the ClinCheck facility.

Methods

The pretreatment, planned, and the digital models after wear of the initial series of aligners regarding adult patients who satisfied selection criteria and were treated using the Invisalign appliance were measured using the Geomagic Control X software (version 2017.0.3; 3D systems, Rock Hill, SC).

Results

A sample of 63 patients with 126 maxillary central incisors satisfied the inclusion criteria. The mean accuracy of the planned torque change of the maxillary central incisors that was achieved was 41.9%. A clinically significant shortfall (≥5°) was detected in 78.6% of the incisors, with the majority showing an underexpression between 10°-15°. Linear regression analyses indicated that weekly or biweekly wear protocols or the presence or absence of power ridges did not influence the accuracy of planned torque expression (P >0.05).

Conclusions

The changes in torque expression with an initial series of Invisalign aligners were less than half of what was planned in patients in which at least a 10° change in lingual root torque of these teeth was prescribed. The presence of power ridges and the aligner change protocol did not appear to significantly affect the accuracy of maxillary central incisor torque expression.
前言:本研究旨在调查通过 ClinCheck 设备进行初始系列隐适美(Align Technology, Santa Clara, Calif)矫治器治疗的患者,其上颌中切牙倾斜度变化大于 10° 时,计划的上颌中切牙舌根扭力与实现的上颌中切牙舌根扭力之间是否存在差异:使用 Geomagic Control X 软件(2017.0.3 版;3D systems,Rock Hill,SC)对符合选择标准并使用隐适美(Invisalign)矫治器进行治疗的成年患者的预处理、计划和佩戴初始系列矫治器后的数字模型进行测量:符合纳入标准的上颌中切牙患者有 63 人,共 126 颗。上颌中切牙计划扭矩变化的平均准确率为 41.9%。在 78.6% 的切牙中发现了临床意义上的明显不足(≥5°),大多数切牙的不足程度在 10°-15° 之间。线性回归分析表明,每周或每两周戴牙一次、有无动力脊并不影响计划扭矩表达的准确性(P >0.05):结论:在对这些牙齿的舌根扭力至少有10°变化的患者中,初始系列隐适美矫正器的扭力变化不到计划的一半。动力脊的存在和矫治器更换方案似乎对上颌中切牙扭力表达的准确性没有显著影响。
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引用次数: 0
The quality of Web-based orthodontic information: A scoping review 网络正畸信息的质量:范围审查。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.05.018

Introduction

Patients seeking health information on the Internet is commonplace. This scoping review aimed to collate and synthesize the evidence regarding the quality of Web-based orthodontic information.

Methods

A systematic search and independent screening process was conducted by 2 independent reviewers across 4 databases. The review was conducted in alignment with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines.

Results

Of 661 records identified, 30 publications satisfied the inclusion criteria. Reviewed studies included those related to the information contained within Web sites regarding dental and orthodontist practices, orthodontic interventions, appliances and auxiliaries, orthodontic conditions commonly requiring orthodontic therapy, issues related to patient experience, and advice during orthodontic treatment. A total of 5 quality of information (QOI) instruments and 3 readability tools were employed, with the University of Oxford, United Kingdom (DISCERN) instrument and the Flesch Reading Ease Score tool being the most frequently used. Most studies determined that the QOI contained within evaluated Web sites was poor and provided suboptimal information related to treatment risks and Web site reliability. Most studies indicated that the information was more difficult to read than recommended by guidelines.

Conclusions

The QOI of orthodontic information available on Web sites was low to moderate, with the readability of content at a level that was considered challenging for many readers to understand. A recommendation for greater involvement of the dental and orthodontic specialty in Web site development was commonplace. Research is required for the development of validated tools that can determine the accuracy of information in addition to Web site reliability.
简介患者在互联网上寻求健康信息已是司空见惯。本范围综述旨在整理和归纳有关网络正畸信息质量的证据:方法:两名独立审查员对 4 个数据库进行了系统搜索和独立筛选。综述按照 PRISMA-ScR(系统综述和 Meta 分析的首选报告项目扩展范围综述)指南进行:在确定的 661 条记录中,有 30 篇出版物符合纳入标准。所审查的研究包括那些与网站中包含的信息相关的研究,这些信息涉及牙科和正畸医师的实践、正畸干预、矫治器和辅助工具、通常需要正畸治疗的正畸状况、与患者体验相关的问题以及正畸治疗期间的建议。共使用了 5 种信息质量(QOI)工具和 3 种可读性工具,其中最常用的是英国牛津大学(DISCERN)工具和 Flesch 阅读容易程度评分工具。大多数研究认为,受评网站的 QOI 不佳,提供的治疗风险和网站可靠性信息不尽人意。大多数研究表明,信息的阅读难度高于指南建议的难度:结论:网站上提供的正畸信息的QOI从低到中度不等,内容的可读性被认为对许多读者来说难以理解。人们普遍建议牙科和正畸专业更多地参与网站开发。除了网站的可靠性之外,还需要研究开发能够确定信息准确性的有效工具。
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引用次数: 0
Authors’ response 作者回复。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.07.013
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引用次数: 0
Journal statistics and backlog issues 期刊统计和积压问题。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.06.015
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引用次数: 0
Information for readers 读者须知
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/S0889-5406(24)00354-8
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引用次数: 0
Comparison of digital study model superimposition methods using implant-supported crowns and best-fit algorithms 使用种植体支撑牙冠和最佳拟合算法的数字研究模型叠加方法比较。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.06.009

Introduction

Research regarding orthodontic changes using the superimposition of digital study models (DSMs) is commonplace. Information regarding the accuracy of data processing by superimposition software is limited. The study aimed to compare different methods of superimposing DSMs using implant-supported crowns (ISC) as a stable reference structure.

Methods

DSMs containing ISCs were sourced from a database of patients treated with clear aligner therapy. The DSM representing the planned treatment outcome was superimposed on the pretreatment DSM. Three tooth points were selected for comparison on the contralateral side of each ISC. Differences in Cartesian coordinates for each tooth point for each arch superimposition method, used by the Geomagic Control X (3D systems, Rock Hill, NC) software system, were recorded. Paired t tests for the reference standard superimposition method best-fit high-resolution using the entire dental arch compared with initial, best-fit low-resolution, and best-fit high-resolution using the ISC only were calculated.

Results

The DSMs of 54 dental arches containing ISCs were evaluated. All mean differences for displacements of selected points on the contralateral side to the ISC in the 3 Cartesian planes were <0.05 mm (P <0.05) and below the threshold of clinical significance. In addition, the standard superimposition techniques (initial, best-fit low-resolution, and best-fit high-resolution) resulted in nonstatistically significant and nonclinically significant differences in the position of the ISC.

Conclusions

Researchers can be confident that the described superimposition methodologies, with and without ISCs as a stable reference structure, are a valid method for accurately assessing most intraarch dental changes.
导言:使用数字研究模型(DSM)叠加进行有关正畸变化的研究已司空见惯。有关叠加软件处理数据准确性的信息却很有限。本研究旨在比较使用种植体支撑冠(ISC)作为稳定参考结构的不同数字研究模型叠加方法:方法:包含ISC的DSM来自于透明矫治器治疗患者的数据库。将代表计划治疗结果的 DSM 叠加到治疗前的 DSM 上。在每个 ISC 的对侧选择三个齿点进行比较。Geomagic Control X(3D systems, Rock Hill, NC)软件系统记录了每种牙弓叠加方法下每个牙点的笛卡尔坐标差异。对使用整个牙弓的参考标准叠加方法最佳拟合高分辨率与仅使用 ISC 的初始、最佳拟合低分辨率和最佳拟合高分辨率进行了配对 t 检验:对包含 ISC 的 54 个牙弓的 DSM 进行了评估。结果:对 54 个含有 ISC 的牙弓的 DSM 进行了评估,在 3 个笛卡尔平面上 ISC 对侧选定点位移的所有平均差均为结论:研究人员可以确信,所描述的叠加方法,无论是否有 ISC 作为稳定的参考结构,都是准确评估大多数牙弓内牙齿变化的有效方法。
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引用次数: 0
Queries regarding changes in malocclusion associated with adulthood psychosocial well-being 关于错牙合畸形的变化与成年后社会心理健康相关的询问。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.07.010
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引用次数: 0
To dichotomize or not dichotomize a continuous predictor 对连续预测因子进行二分法或不进行二分法。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.07.009
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引用次数: 0
When history needs to be ignored 当历史需要被忽略时。
IF 2.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.ajodo.2024.07.005
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引用次数: 0
期刊
American Journal of Orthodontics and Dentofacial Orthopedics
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