Pub Date : 2024-07-26DOI: 10.12688/wellcomeopenres.22606.1
Bob Vandendriessche, An Martel, Meike Mai, E. Teeling, Sonja C. Vernes
We present a genome assembly from an individual male Vespertilio murinus (the particolored bat; Chordata; Mammalia; Chiroptera; Vespertilionidae). The genome sequence is 1,925.6 megabases in span. Most of the assembly is scaffolded into 20 chromosomal pseudomolecules, including the X and Y sex chromosomes. The mitochondrial genome has also been assembled and is 16.96 kilobases in length.
我们展示了一个雄性个体 Vespertilio murinus（微色蝙蝠；脊索动物门；哺乳纲；爬行纲；蝙蝠科）的基因组序列。基因组序列跨度为 1,925.6 兆字节。大部分基因组组装成 20 个染色体假分子支架，包括 X 和 Y 性染色体。线粒体基因组也已组装完成，长度为 16.96 千碱基。
{"title":"The genome sequence of the particolored bat, Vespertilio murinus Linnaeus, 1758","authors":"Bob Vandendriessche, An Martel, Meike Mai, E. Teeling, Sonja C. Vernes","doi":"10.12688/wellcomeopenres.22606.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.22606.1","url":null,"abstract":"We present a genome assembly from an individual male Vespertilio murinus (the particolored bat; Chordata; Mammalia; Chiroptera; Vespertilionidae). The genome sequence is 1,925.6 megabases in span. Most of the assembly is scaffolded into 20 chromosomal pseudomolecules, including the X and Y sex chromosomes. The mitochondrial genome has also been assembled and is 16.96 kilobases in length.","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"31 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.12688/wellcomeopenres.22694.1
B. Halpern, Judit Vörös, Ann M. Mc Cartney, Giulio Formenti, Alice Mouton
We present a genome assembly from an individual female Vipera ursinii rakosiensis (the Hungarian meadow viper; Chordata; Lepidosauria; Squamata; Viperidae). The genome sequence is 1,625.0 megabases in span. Most of the assembly is scaffolded into 19 chromosomal pseudomolecules, including the W and Z sex chromosomes. The mitochondrial genome has also been assembled and is 17.38 kilobases in length.
我们展示了一个雌性蝰蛇个体（匈牙利草地蝰；脊索动物门；雷龙科；有鳞目；蝰科）的基因组序列。基因组序列的跨度为 1625.0 兆字节。大部分序列组装成 19 个染色体假分子支架，包括 W 和 Z 性染色体。线粒体基因组也已组装完成，长度为 17.38 千碱基。
{"title":"The genome sequence of the Hungarian meadow viper, Vipera ursinii rakosiensis Méhely, 1893","authors":"B. Halpern, Judit Vörös, Ann M. Mc Cartney, Giulio Formenti, Alice Mouton","doi":"10.12688/wellcomeopenres.22694.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.22694.1","url":null,"abstract":"We present a genome assembly from an individual female Vipera ursinii rakosiensis (the Hungarian meadow viper; Chordata; Lepidosauria; Squamata; Viperidae). The genome sequence is 1,625.0 megabases in span. Most of the assembly is scaffolded into 19 chromosomal pseudomolecules, including the W and Z sex chromosomes. The mitochondrial genome has also been assembled and is 17.38 kilobases in length.","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141801425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.12688/wellcomeopenres.22762.1
Steve Garland
We present a genome assembly from an individual female Agrilus biguttatus (jewel beetle; Arthropoda; Insecta; Coleoptera; Buprestidae). The genome sequence spans 368.10 megabases. Most of the assembly is scaffolded into 11 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled and is 17.41 kilobases in length.
{"title":"The genome sequence of a jewel beetle, Agrilus biguttatus (Fabricius, 1776)","authors":"Steve Garland","doi":"10.12688/wellcomeopenres.22762.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.22762.1","url":null,"abstract":"We present a genome assembly from an individual female Agrilus biguttatus (jewel beetle; Arthropoda; Insecta; Coleoptera; Buprestidae). The genome sequence spans 368.10 megabases. Most of the assembly is scaffolded into 11 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled and is 17.41 kilobases in length.","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"37 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-24DOI: 10.12688/wellcomeopenres.22543.1
Matt Butler, Catherine Bird, Carolina Maggio, Amy Durden, N. Modlin, Kete Campbell-Coker, Mark J Edwards, Susannah Pick, L. M. Millman, Emily Lowery, C.S.K. Bhagavan, Richard Kanaan, Dawn Golder, Bridget Mildon, Mitul Mehta, James Rucker, Timothy Nicholson
Background Functional neurological disorder (FND) is a common cause of neurological symptoms including paralysis, seizures, and movement disorders. It is often debilitating, is associated with high health and social care costs, and can have a poor prognosis. Functional magnetic resonance imaging (fMRI) has suggested FND is a multi-network disorder; the default mode network (DMN) may be specifically implicated. Converging evidence suggests that other variable mechanisms including dissociation, interoception, and motor agency may be differentially abnormal in people with FND. Psychedelics are currently under investigation for numerous neuropsychiatric disorders and have been shown to disrupt functional networks such as the DMN. Administering psychedelics to people with FND will help us to probe mechanistic theories of the disorder. Protocol In this open-label neuroimaging study, we will administer 25mg oral psilocybin with psychological support to people with chronic FND (target n = 24). Participants will undergo resting-state and task-based (Libet’s clock, a measure of motor agency) fMRI sequences which will be compared in a pre-post manner. Additional mechanistic outcomes including measures of interoception (heartbeat tracking task), somatisation, illness perceptions, imaginative suggestibility, and dissociation will be collected. Data on expectancy, preparedness, and subjective experience of the psychedelic experience will also be gathered. Participants will be followed up for three months following psilocybin administration. fMRI changes in networks such as the DMN will be analysed using seed-based approaches, and additional exploratory analysis of resting-state imaging will take place. Discussion The study will help us to probe the mechanisms thought to potentially underpin FND. As the first modern study of psychedelics in FND, it will also help us to understand whether psychedelic administration alongside psychological support might be safe and feasible in this patient population.
{"title":"Probing the functional magnetic resonance imaging response to psilocybin in functional neurological disorder (PsiFUND): study protocol","authors":"Matt Butler, Catherine Bird, Carolina Maggio, Amy Durden, N. Modlin, Kete Campbell-Coker, Mark J Edwards, Susannah Pick, L. M. Millman, Emily Lowery, C.S.K. Bhagavan, Richard Kanaan, Dawn Golder, Bridget Mildon, Mitul Mehta, James Rucker, Timothy Nicholson","doi":"10.12688/wellcomeopenres.22543.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.22543.1","url":null,"abstract":"Background Functional neurological disorder (FND) is a common cause of neurological symptoms including paralysis, seizures, and movement disorders. It is often debilitating, is associated with high health and social care costs, and can have a poor prognosis. Functional magnetic resonance imaging (fMRI) has suggested FND is a multi-network disorder; the default mode network (DMN) may be specifically implicated. Converging evidence suggests that other variable mechanisms including dissociation, interoception, and motor agency may be differentially abnormal in people with FND. Psychedelics are currently under investigation for numerous neuropsychiatric disorders and have been shown to disrupt functional networks such as the DMN. Administering psychedelics to people with FND will help us to probe mechanistic theories of the disorder. Protocol In this open-label neuroimaging study, we will administer 25mg oral psilocybin with psychological support to people with chronic FND (target n = 24). Participants will undergo resting-state and task-based (Libet’s clock, a measure of motor agency) fMRI sequences which will be compared in a pre-post manner. Additional mechanistic outcomes including measures of interoception (heartbeat tracking task), somatisation, illness perceptions, imaginative suggestibility, and dissociation will be collected. Data on expectancy, preparedness, and subjective experience of the psychedelic experience will also be gathered. Participants will be followed up for three months following psilocybin administration. fMRI changes in networks such as the DMN will be analysed using seed-based approaches, and additional exploratory analysis of resting-state imaging will take place. Discussion The study will help us to probe the mechanisms thought to potentially underpin FND. As the first modern study of psychedelics in FND, it will also help us to understand whether psychedelic administration alongside psychological support might be safe and feasible in this patient population.","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"19 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141806298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-24DOI: 10.12688/wellcomeopenres.21664.1
Oscar Castro, E. Norris, Alison J. Wright, Emily Hayes, Ella Howes, Candice Moore, Robert West, Susan Michie
Background The Human Behaviour-Change Project (HBCP) aims to improve evidence synthesis in behavioural science by compiling intervention reports, annotating them according to an ontology, and using the resulting data to train information extraction and prediction algorithms. The HBCP used smoking cessation as the first ‘proof of concept’ domain but intends to extend its methodology to other behaviours. The aims of this paper are to (i) assess the extent to which methods developed for annotating smoking cessation intervention reports were generalisable to a corpus of evidence relating to a different behaviour, namely physical activity, and (ii) describe the steps involved in developing this second HBCP corpus. Methods The development of the physical activity corpus took place in four stages: (i) reviewing the suitability of smoking cessation codes already used in the HBCP, (ii) defining the selection criteria and scope of the corpus, (iii) identifying and screening records for inclusion, and (iv) annotating intervention reports using a code set of 200+ entities from the Behaviour Change Intervention Ontology. Results Stage 1 highlighted the need to modify the smoking cessation behavioural outcome codes for application to physical activity. One hundred physical activity intervention reports were reviewed, and 11 physical activity experts were consulted to inform the adapted code set. Stage 2 involved narrowing down the scope of the corpus to interventions targeting moderate-to-vigorous physical activity. In stage 3, 111 physical activity intervention reports were identified, which were then annotated in stage 4. Conclusions Smoking cessation annotation methods developed as part of the HBCP were mostly transferable to the physical activity domain. However, the codes applied to behavioural outcome variables required adaptations. This paper can help anyone interested in building a body of research to develop automated evidence synthesis methods in physical activity or for other behaviours.
{"title":"Creating a body of physical activity evidence to test the generalisation of annotation methods for automated evidence synthesis","authors":"Oscar Castro, E. Norris, Alison J. Wright, Emily Hayes, Ella Howes, Candice Moore, Robert West, Susan Michie","doi":"10.12688/wellcomeopenres.21664.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.21664.1","url":null,"abstract":"Background The Human Behaviour-Change Project (HBCP) aims to improve evidence synthesis in behavioural science by compiling intervention reports, annotating them according to an ontology, and using the resulting data to train information extraction and prediction algorithms. The HBCP used smoking cessation as the first ‘proof of concept’ domain but intends to extend its methodology to other behaviours. The aims of this paper are to (i) assess the extent to which methods developed for annotating smoking cessation intervention reports were generalisable to a corpus of evidence relating to a different behaviour, namely physical activity, and (ii) describe the steps involved in developing this second HBCP corpus. Methods The development of the physical activity corpus took place in four stages: (i) reviewing the suitability of smoking cessation codes already used in the HBCP, (ii) defining the selection criteria and scope of the corpus, (iii) identifying and screening records for inclusion, and (iv) annotating intervention reports using a code set of 200+ entities from the Behaviour Change Intervention Ontology. Results Stage 1 highlighted the need to modify the smoking cessation behavioural outcome codes for application to physical activity. One hundred physical activity intervention reports were reviewed, and 11 physical activity experts were consulted to inform the adapted code set. Stage 2 involved narrowing down the scope of the corpus to interventions targeting moderate-to-vigorous physical activity. In stage 3, 111 physical activity intervention reports were identified, which were then annotated in stage 4. Conclusions Smoking cessation annotation methods developed as part of the HBCP were mostly transferable to the physical activity domain. However, the codes applied to behavioural outcome variables required adaptations. This paper can help anyone interested in building a body of research to develop automated evidence synthesis methods in physical activity or for other behaviours.","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141806447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-24DOI: 10.12688/wellcomeopenres.20193.1
E. Charani, Sipho Dlamini, Anastasia Koch, Sanjeev Singh, Rebecca Hodes, Ramanan Laxminarayan, D. Batheja, Elelwani L. Ramugondo, A. S. Mukherjee, M. Mendelson
Across social structures within society, including healthcare, power relations manifest according to gender, socioeconomic status, race, ethnicity, and class influencing infection related healthcare access and health providing-behaviours. Therefore, accounting for sociocultural drivers, including gender, race, and class, and their influence on economic status can improve healthcare access and health-providing behaviours in infection prevention and control (IPC) as well as antibiotic use, which in turn helps mitigate the spread of antimicrobial resistance (AMR). This Wellcome funded research will investigate how and why the social determinants of health and economic status influence how people seek, experience, and provide healthcare for suspected or proven (bacterial) infections and how these factors influence antibiotic prescribing and use in South Africa (upper middle-income country) and India (lower middle-income country). The aim of this body of work is to, (1) define and estimate the sociocultural and economic drivers for AMR in different resource settings, (2) design, implement and evaluate context-sensitive IPC and antimicrobial stewardship (AMS) interventions, and (3) inform policy and strategy for AMR mitigation. The population will be healthcare workers (HCWs), patients, and their carers across acute medical and surgical pathways where IPC and antibiotic-related healthcare access and health-providing behaviours will be studied. Qualitative methods will include ethnographic research, semi-structured in-depth interviews, and focus groups with healthcare providers, patients and carers. Quantitative analysis of bedside observational data from hospitals and population level data on antibiotic use will study the various predictors of AMR using bivariable and multivariable regression analyses. The research will provide high-quality evidence on how social determinants intersect with health, social well-being, and vulnerability in IPC practices and antibiotic use. Using this knowledge we will: 1) design, implement, and measure effects of interventions accounting for these factors; 2) provide a toolkit for advocacy for actors in AMR, and healthcare to assist them to promote dialogue, including policy dialogue on this issue. This work directly benefits the target population and informs healthcare services and practice across the participating countries with potential for wider translation. The setting will be hospitals in South Africa (middle-income country) and India (lower middle-income country). The population will be healthcare workers (HCWs), patients, and their carers across acute medical and surgical pathways where IPC and antibiotic-related health-seeking and health-providing behaviours will be studied. These populations represent communities most affected by infections and AMR because existing interventions do not address a) differences in how surgical versus medical teams manage infections; b) the role of the wider social network of indi
在包括医疗保健在内的整个社会结构中，权力关系表现为性别、社会经济地位、种族、民族和阶级，影响着与感染相关的医疗保健的获取和医疗服务的提供行为。因此，考虑包括性别、种族和阶级在内的社会文化驱动因素及其对经济地位的影响，可以改善感染预防和控制 (IPC) 以及抗生素使用方面的医疗保健获取和保健提供行为，进而有助于缓解抗菌药耐药性 (AMR) 的传播。这项由惠康资助的研究将调查在南非（中等偏上收入国家）和印度（中等偏下收入国家），健康和经济状况的社会决定因素如何以及为什么会影响人们如何寻求、经历和提供疑似或已证实（细菌）感染的医疗服务，以及这些因素如何影响抗生素的处方和使用。这项工作的目的是：(1) 界定和估算不同资源环境中造成 AMR 的社会文化和经济驱动因素；(2) 设计、实施和评估对具体情况敏感的 IPC 和抗菌药物管理 (AMS) 干预措施；(3) 为减轻 AMR 的政策和战略提供信息。研究对象将是急诊内科和外科路径中的医护人员、患者及其护理人员，在这些路径中，将对 IPC 和抗生素相关的医疗服务获取和医疗服务提供行为进行研究。定性方法将包括人种学研究、半结构式深度访谈以及与医疗服务提供者、患者和护理人员进行的焦点小组讨论。对来自医院的床边观察数据和抗生素使用的人口数据进行定量分析后，将使用二变量和多变量回归分析法研究 AMR 的各种预测因素。这项研究将提供高质量的证据，说明社会决定因素如何与健康、社会福利以及 IPC 实践和抗生素使用中的脆弱性相互交织。利用这些知识，我们将1）设计、实施和衡量考虑到这些因素的干预措施的效果；2）为抗逆转录病毒（AMR）和医疗保健领域的参与者提供宣传工具包，协助他们促进对话，包括有关这一问题的政策对话。这项工作将直接惠及目标人群，为参与国的医疗服务和实践提供信息，并有可能在更大范围内推广。研究地点为南非（中等收入国家）和印度（中低收入国家）的医院。研究对象为急诊内科和外科的医护人员（HCWs）、患者及其护理人员，研究内容包括 IPC 以及与抗生素相关的求医行为和医疗服务行为。这些人群代表了受感染和 AMR 影响最严重的社区，因为现有的干预措施并没有解决以下问题：a) 外科团队与医疗团队在管理感染方面的差异；b) 个人更广泛的社会网络对其决策的影响；c) 健康的社会决定因素（包括种族、性别、社会经济贫困）与 AMR 的交叉影响。
{"title":"Power Relations in Optimisation of Therapies and Equity in Access to Antibiotics (PROTEA) Study: investigating the intersection of socio-economic and cultural drivers on antimicrobial resistance (AMR) and its influence on healthcare access and health-providing behaviours in India and South Africa","authors":"E. Charani, Sipho Dlamini, Anastasia Koch, Sanjeev Singh, Rebecca Hodes, Ramanan Laxminarayan, D. Batheja, Elelwani L. Ramugondo, A. S. Mukherjee, M. Mendelson","doi":"10.12688/wellcomeopenres.20193.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.20193.1","url":null,"abstract":"Across social structures within society, including healthcare, power relations manifest according to gender, socioeconomic status, race, ethnicity, and class influencing infection related healthcare access and health providing-behaviours. Therefore, accounting for sociocultural drivers, including gender, race, and class, and their influence on economic status can improve healthcare access and health-providing behaviours in infection prevention and control (IPC) as well as antibiotic use, which in turn helps mitigate the spread of antimicrobial resistance (AMR). This Wellcome funded research will investigate how and why the social determinants of health and economic status influence how people seek, experience, and provide healthcare for suspected or proven (bacterial) infections and how these factors influence antibiotic prescribing and use in South Africa (upper middle-income country) and India (lower middle-income country). The aim of this body of work is to, (1) define and estimate the sociocultural and economic drivers for AMR in different resource settings, (2) design, implement and evaluate context-sensitive IPC and antimicrobial stewardship (AMS) interventions, and (3) inform policy and strategy for AMR mitigation. The population will be healthcare workers (HCWs), patients, and their carers across acute medical and surgical pathways where IPC and antibiotic-related healthcare access and health-providing behaviours will be studied. Qualitative methods will include ethnographic research, semi-structured in-depth interviews, and focus groups with healthcare providers, patients and carers. Quantitative analysis of bedside observational data from hospitals and population level data on antibiotic use will study the various predictors of AMR using bivariable and multivariable regression analyses. The research will provide high-quality evidence on how social determinants intersect with health, social well-being, and vulnerability in IPC practices and antibiotic use. Using this knowledge we will: 1) design, implement, and measure effects of interventions accounting for these factors; 2) provide a toolkit for advocacy for actors in AMR, and healthcare to assist them to promote dialogue, including policy dialogue on this issue. This work directly benefits the target population and informs healthcare services and practice across the participating countries with potential for wider translation. The setting will be hospitals in South Africa (middle-income country) and India (lower middle-income country). The population will be healthcare workers (HCWs), patients, and their carers across acute medical and surgical pathways where IPC and antibiotic-related health-seeking and health-providing behaviours will be studied. These populations represent communities most affected by infections and AMR because existing interventions do not address a) differences in how surgical versus medical teams manage infections; b) the role of the wider social network of indi","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"38 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141807263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-22DOI: 10.12688/wellcomeopenres.22704.1
Simon Taylor, Bas Payne, Vengamanaidu Modepalli
We present a genome assembly from an individual Mytilus edulis (the blue mussel; Mollusca; Bivalvia; Mytilida; Mytilidae). The genome sequence is 1,368.4 megabases in span. Most of the assembly is scaffolded into 14 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 16.75 kilobases in length.
{"title":"The genome sequence of the blue mussel, Mytilus edulis Linnaeus, 1758","authors":"Simon Taylor, Bas Payne, Vengamanaidu Modepalli","doi":"10.12688/wellcomeopenres.22704.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.22704.1","url":null,"abstract":"We present a genome assembly from an individual Mytilus edulis (the blue mussel; Mollusca; Bivalvia; Mytilida; Mytilidae). The genome sequence is 1,368.4 megabases in span. Most of the assembly is scaffolded into 14 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 16.75 kilobases in length.","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"67 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141817827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-22DOI: 10.12688/wellcomeopenres.22745.1
Stephen Moran
We present a genome assembly from an individual female Orchestes rusci (the jumping weevil; Arthropoda; Insecta; Coleoptera; Curculionidae). The genome sequence spans 624.00 megabases. Most of the assembly is scaffolded into 12 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled and is 21.73 kilobases in length.
{"title":"The genome sequence of the jumping weevil, Orchestes rusci (Herbst, 1795)","authors":"Stephen Moran","doi":"10.12688/wellcomeopenres.22745.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.22745.1","url":null,"abstract":"We present a genome assembly from an individual female Orchestes rusci (the jumping weevil; Arthropoda; Insecta; Coleoptera; Curculionidae). The genome sequence spans 624.00 megabases. Most of the assembly is scaffolded into 12 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled and is 21.73 kilobases in length.","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"38 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141814917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-22DOI: 10.12688/wellcomeopenres.22747.1
Michelle F. O'Brien, Rosa Lopez Colom
We present a genome assembly from an individual female Micromys minutus (the European harvest mouse; Chordata; Mammalia; Rodentia; Muridae). The genome sequence spans 2,651.80 megabases. Most of the assembly is scaffolded into 34 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled and is 16.24 kilobases in length.
我们展示了欧洲丰收鼠（Micromys minutus；脊索动物门；哺乳纲；啮齿目；鼠科）雌性个体的基因组序列。基因组序列跨度为 2,651.80 兆字节。大部分序列组装成 34 个染色体假分子支架，其中包括 X 性染色体。线粒体基因组也已组装完成，长度为 16.24 千碱基。
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Pub Date : 2024-07-22DOI: 10.12688/wellcomeopenres.22741.1
Rosa Lopez Colom, Michelle F. O'Brien
We present a genome assembly from an individual male Chroicocephalus ridibundus (the black-headed gull; Chordata; Aves; Charadriiformes; Laridae). The genome sequence spans 1,417.60 megabases. Most of the assembly is scaffolded into 33 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genome has also been assembled and is 16.82 kilobases in length.
我们展示了一个雄性黑头鸥（Chroicocephalus ridibundus；脊索动物门；有翅目；蝶形目；鸥科）个体的基因组序列。基因组序列跨度为 1,417.60 兆字节。大部分基因组组装成 33 个染色体假分子支架，其中包括 Z 性染色体。线粒体基因组也已组装完成，长度为 16.82 千碱基。
{"title":"The genome sequence of the black-headed gull, Chroicocephalus ridibundus (Linnaeus, 1766)","authors":"Rosa Lopez Colom, Michelle F. O'Brien","doi":"10.12688/wellcomeopenres.22741.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.22741.1","url":null,"abstract":"We present a genome assembly from an individual male Chroicocephalus ridibundus (the black-headed gull; Chordata; Aves; Charadriiformes; Laridae). The genome sequence spans 1,417.60 megabases. Most of the assembly is scaffolded into 33 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genome has also been assembled and is 16.82 kilobases in length.","PeriodicalId":508490,"journal":{"name":"Wellcome Open Research","volume":"9 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141817393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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