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Extended Post-Traumatic Pneumorachis: A Case Report and Review of the Literature 创伤后扩展性气胸:病例报告和文献综述
Pub Date : 2024-06-12 DOI: 10.24018/ejmed.2024.6.3.2111
Salma Lahlou, K. Baayoud, Amine El Khamouye, A. Chellaoui, Khadija Ibahiouin, A. Lakhdar
Pneumorachis is an uncommon condition wherein air infiltrates the spinal canal. The pathophysiology of this condition is still a matter of debate, depending on the type of traumatic mechanism (open or closed) and the assessment of the associated injuries. This report aims to present a case of pneumorachis and comprehensively review the literature to gain a better understanding of the etiologies, associated lesions, and neurological symptoms. By doing so, we hope to enhance our knowledge of the management and modalities of treatment for this condition. Although there are many cases of pneumorachis reported in the literature, none are widespread.
椎管积气是一种空气渗入椎管的不常见疾病。这种疾病的病理生理学仍存在争议,这取决于创伤机制的类型(开放性或闭合性)以及对相关损伤的评估。本报告旨在介绍一例气囊炎病例,并全面回顾相关文献,以便更好地了解其病因、相关病变和神经症状。我们希望通过这样的研究,加深我们对这种疾病的管理和治疗方法的了解。虽然文献中报道了许多气哽症病例,但没有一个病例是普遍存在的。
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引用次数: 0
Scrotal Dermatofibrosarcoma Protuberance: A Case Review at Mankweng Academic Hospital 阴囊皮纤维肉瘤突起:曼昆学术医院病例回顾
Pub Date : 2024-06-07 DOI: 10.24018/ejmed.2024.6.3.2123
Lerato Hector Nong, F. Makhandule, Dumisa Ntshani, Mirza Bhuiyan
Background: Dermatofibrosarcoma Protuberance (DFSP) is an uncommon slow-growing soft tissue tumour. The overall incidence of DFSP in the population ranges from 0.3–5 per million and is more common in blacks than whites, males and females are affected equally. The main objective of this case report is to share our experience with Dermatofibrosarcoma Protuberance and give a literature review on the standard of care.Case Presentation: A 28-year-old male presented to the outpatient department with a five-year history of a painless right inguinoscrotal mass. On physical examination the mass was lobulated, fixed to the underlying tissue, it was non-tender measured 8 X 8 cm and there were no inguinal lymph nodes palpable. Ultrasound showed a hypervascular soft tissue tumour not involving the testicle. Wide Local Excision was performed, and histology showed a protuberant ulcerated nodule. A staging CT scan of the chest and abdomen was normal with no features of any metastatic lesions.Conclusion: DFSP is a slow-growing and locally aggressive tumor. Therefore, early diagnosis and complete surgical resection can result in patients being cured. Mohs micrographic surgery is becoming the treatment of choice for DFSP as it results in complete surgical clearance. Imatinib is a novel treatment option for DFSP and is increasingly being used.
背景:皮纤维肉瘤(DFSP)是一种不常见的生长缓慢的软组织肿瘤。皮纤维肉瘤在人群中的总发病率为 0.3-5/百万,黑人比白人更常见,男性和女性的发病率相同。本病例报告的主要目的是分享我们治疗皮纤维肉瘤突起的经验,并就标准治疗方法进行文献综述:一名 28 岁男性因右侧阴囊内无痛性肿块就诊 5 年。体格检查时,肿块呈分叶状,与下层组织固定,无触痛,大小为 8 X 8 厘米,未触及腹股沟淋巴结。超声波检查显示这是一个血管丰富的软组织肿瘤,没有累及睾丸。对肿瘤进行了大范围局部切除,组织学检查显示肿瘤为突起的溃疡性结节。胸部和腹部的分期 CT 扫描结果正常,未发现任何转移病灶:结论:DFSP是一种生长缓慢、局部侵袭性强的肿瘤。结论:DFSP 是一种生长缓慢、局部侵袭性强的肿瘤,因此,早期诊断和彻底手术切除可使患者痊愈。莫氏显微外科手术能彻底清除肿瘤,因此已成为治疗 DFSP 的首选方法。伊马替尼(Imatinib)是一种新型的 DFSP 治疗方法,目前正得到越来越多的应用。
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引用次数: 0
The Significance of TNF-α, CRP, and Hematological Parameters in the Prediction of Plasmodium Falciparum Parasitemia TNF-α、CRP 和血液学参数在预测疟原虫寄生虫病中的意义
Pub Date : 2024-04-16 DOI: 10.24018/ejmed.2024.6.2.2055
Samah Abdelrahman Hassan Ibrahim, Zeinab Ibrahim Swar Eldahab
Malaria remains a significant public health concern in Sudan, with Plasmodium falciparum (P. falciparum) infection having widespread indirect consequences. Effective identification of infection severity is crucial for preventing complications. This study aimed to assess the predictive value of Tumor Necrosis Factor Alpha (TNF-α), C-reactive protein (CRP), and hematological parameters in P. falciparum parasitemia. The three-month cross-sectional study involved 54 P. falciparum-positive patients at Bashaire Teaching Hospital Khartoum, Sudan, along with an equal number of P. falciparum-negative individuals. Participants underwent Antigen Rapid Diagnostic Test (RDT), TNFα, CRP, and Complete Blood Count (CBC) assessments. The infected group comprised 68.5% male patients, with a mean age of 22.3 years. Significant variations were observed between the infected and uninfected groups in TNFα, CRP, Total White Blood Cells (TWBCs), and neutrophil levels, with infected individuals showing higher values. Conversely, infected individuals had lower hemoglobin, Red Blood Cells (RBCs), Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), platelets, and lymphocytes. The study revealed a noteworthy association between MCV and parasitemia, while TNFα, CRP, Hb, RBCs, MCH, and MCHC showed no significant correlation. Hematological parameters should be considered in malaria patients.
疟疾仍然是苏丹的一个重大公共卫生问题,恶性疟原虫(P. falciparum)感染造成了广泛的间接后果。有效识别感染严重程度对于预防并发症至关重要。本研究旨在评估肿瘤坏死因子α(TNF-α)、C反应蛋白(CRP)和血液学参数对恶性疟原虫寄生虫血症的预测价值。这项为期三个月的横断面研究涉及苏丹喀土穆 Bashaire 教学医院的 54 名恶性疟原虫阳性患者,以及同等数量的恶性疟原虫阴性患者。参与者接受了抗原快速诊断测试(RDT)、TNFα、CRP和全血细胞计数(CBC)评估。感染组中男性患者占 68.5%,平均年龄为 22.3 岁。感染组和未感染组的 TNFα、CRP、白细胞总数(TWBC)和中性粒细胞水平存在显著差异,感染者的数值更高。相反,受感染者的血红蛋白、红细胞(RBC)、平均体细胞容积(MCV)、平均体细胞血红蛋白(MCH)、平均体细胞血红蛋白浓度(MCHC)、血小板和淋巴细胞水平较低。研究显示,MCV 与寄生虫血症之间存在显著关联,而 TNFα、CRP、Hb、RBCs、MCH 和 MCHC 则无明显关联。疟疾患者应考虑血液学参数。
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引用次数: 0
Malignant Medulloepithelioma of the Ciliary Body Revealed by Neovascular Glaucoma in a 13-Year-Old Child 一名 13 岁儿童因新生血管性青光眼而发现的睫状体恶性髓上皮瘤
Pub Date : 2024-04-15 DOI: 10.24018/ejmed.2024.6.2.1975
Chaimae Baqadir, R. Chahir, Meriem El Alami, Achraf Slimane, G. Daghouj, L. El maaloum, B. Allali, A. EL kettani
Medulloepithelioma of the ciliary body is a rare congenital intraocular tumor occurring more frequently in children. It develops from the unpigmented epithelium of the ciliary body. Positive diagnosis relies essentially on anatomopathological examination. In our article, we report a case of malignant medulloepithelioma of the ciliary body in a 13-year-old child revealed by severe panuveitis complicated by neovascular glaucoma and non-axial exophthalmos.
睫状体髓上皮瘤是一种罕见的先天性眼内肿瘤,多发于儿童。它由睫状体的无色素上皮发展而来。阳性诊断主要依靠解剖病理学检查。在我们的文章中,我们报告了一例睫状体恶性髓上皮瘤病例,患儿 13 岁,因严重的全葡萄膜炎并发新生血管性青光眼和非轴性眼球外翻而显露出来。
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引用次数: 0
Utilization of Female Condoms among Women Living with Human Immunodeficiency Virus (HIV) in Murang’a County, Kenya 肯尼亚穆朗阿县感染人类免疫缺陷病毒(HIV)的妇女使用女用安全套的情况
Pub Date : 2024-04-12 DOI: 10.24018/ejmed.2024.6.2.2040
Dorothy Njoki Ndwiga, Judy Mugo, Edna Nyang’echi, J. Mathenge
Background: To prevent the risk of transmission of the Human Immune Deficiency Virus (HIV) and other sexually transmitted infections (STIs), as well as achieve family planning targets, the use of Female Condom, a women-initiated method, has been prioritized across the globe. Nevertheless, knowledge regarding the utilization of Female Condoms among HIV-positive women remains inconclusive. The main objective of this study was to determine the utilization of Female Condoms (FC) among HIV-positive women in Murang’a County, Kenya.Method: This study adopted a cross-sectional analytical survey design. A total of 204 women living with HIV (WLHIV) were recruited in the study. Multi-stage sampling was conducted to get three participating sub-counties and three clinics. Systematic sampling and purposive sampling techniques were used to select WLHIV. Structured questionnaires, interview schedules and focus group discussions were used to collect data. Descriptive and inferential statistics were generated using Statistical Package for Social Sciences (SPSS) version 25.0. The statistical significance of the association between categorical variables was determined using Pearson’s Chi-square test. The level of significance was fixed at a P-value of 0.05 level of significance (p ≤ 0.05).Results: 38.8% of the respondents were aged 31–40 years (Mean = 3.11; SD = 1.004). 42.2% of study participants had attained secondary education (mean = 2.05; SD = 0.899). FC use was low at 17.6% among the women living with HIV. There was a statistically significant association between the age of the respondents and the view that FC has the potential to prevent unwanted pregnancy (p = 0.002; χ2 = 17.246; df = 4). The relationship between marital status and “ever heard about FC” (p = 0.042; χ2 = 32.529; df = 5), “ever seen an FC” (p = 0.048; χ2 = 34.982; df = 5), “FC has a potential to prevent unwanted pregnancy” (p = 0.006; χ2 = 23.079; df = 5) was significant. Married women who were revealed to have seen FC were significantly associated with the current use of the FC (p = 0.001; χ2 = 12.852; df = 1). 26.5% of the participants put on FC as a measure to prevent HIV during sexual activities. Most married women did not know whether their sexual partner does not like them to use FC when having sex compared to separated, cohabiting, divorced or single WLHIV (p=0.034; χ2=7.949; df = 10).Conclusion: The relatively high knowledge among WLHIV does not translate to the use of FC for appropriate and consistent utilization of the device.
背景:为了预防人类免疫缺陷病毒(HIV)和其他性传播疾病(STI)的传播风险,以及实现计划生育目标,全球各地都优先考虑使用女性安全套这种由女性发起的方法。然而,关于女性安全套在 HIV 阳性女性中的使用情况,目前仍无定论。本研究的主要目的是确定肯尼亚穆朗阿县 HIV 阳性女性对女用安全套(FC)的使用情况:本研究采用横断面分析调查设计。研究共招募了 204 名女性艾滋病病毒感染者(WLHIV)。通过多阶段抽样,获得了三个参与分县和三个诊所。在选择 WLHIV 时,使用了系统抽样和目的性抽样技术。收集数据时使用了结构化问卷、访谈表和焦点小组讨论。使用社会科学统计软件包(SPSS)25.0 版生成了描述性和推论性统计数据。使用皮尔逊卡方检验确定分类变量之间关联的统计显著性。显著性水平的 P 值为 0.05(P ≤ 0.05):38.8%的受访者年龄在 31-40 岁之间(平均值 = 3.11;标准差 = 1.004)。42.2%的受访者受过中等教育(平均值=2.05;标准差=0.899)。感染艾滋病毒的妇女中使用 FC 的比例较低,仅为 17.6%。受访者的年龄与 "FC 有可能防止意外怀孕 "的观点之间存在统计学意义上的显著关联(p = 0.002;χ2 = 17.246;df = 4)。婚姻状况与 "听说过 FC"(p = 0.042;χ2 = 32.529;df = 5)、"见过 FC"(p = 0.048;χ2 = 34.982;df = 5)、"FC 有可能防止意外怀孕"(p = 0.006;χ2 = 23.079;df = 5)之间的关系显著。已婚妇女被揭示曾见过 FC 与目前使用 FC 有明显相关性(p = 0.001;χ2 = 12.852;df = 1)。26.5%的参与者在性活动中使用 FC 作为预防艾滋病毒的措施。与分居、同居、离婚或单身的 WLHIV 相比,大多数已婚妇女不知道她们的性伴侣是否不喜欢她们在发生性行为时使用 FC(p=0.034;χ2=7.949;df=10):WLHIV对FC的了解程度相对较高,但这并不意味着他们会适当、持续地使用FC。
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引用次数: 0
Multiple Disseminated Hydatidosis with Rare Locations: Mediastinal, Pancreatic and Pelvic (Case Report) 位置罕见的多发性播散性包虫病:纵隔、胰腺和盆腔(病例报告纵隔、胰腺和盆腔(病例报告)
Pub Date : 2024-04-04 DOI: 10.24018/ejmed.2024.6.2.1944
Wafaa Bennane, Aziz Moussahim, Y. Chakir, Maha Soussi Abdallaoui, Abdelaziz Fadil, Rachid Aboutaeib
Hydatid disease is an anthropozoonosis due to the development of the larval form of Echinococcus granulosus in the human body, which constitutes a ‘dead-end’ host. It’s a common parasitosis in North African countries and constitutes a public health problem in Morocco. The liver and lung are the most affected while the mediastinum, pancreas and pelvis are rarely affected. We report the case of a 40-year-old patient operated 15 yearsago for cerebral and cervical hydatid cysts and who was hospitalized for  generalized mucocutaneous jaundice. On exploration, we discover the presence of disseminated abdominal hydatidosis with association of 3 rare locations: mediastinal, pancreatic and pelvic. Indirect diagnostic tests were positive: indirect hemagglutination (IHA) and Elisa. The Western blot test also showed the presence of specific bands, thus making it possible to retain the diagnosis of hydatidosis. The hydatid cyst with mediastinal, pancreatic and pelvic location is rare and their association is very exceptional. It is essential to evoke the hydatid origin of any cystic lesion in a patient staying in an endemic area.
水囊虫病是一种蚁虫病,是由于棘球蚴的幼虫在人体内发育而引起的,它是一种 "死亡 "宿主。这是北非国家常见的寄生虫病,也是摩洛哥的一个公共卫生问题。肝脏和肺部最受影响,而纵隔、胰腺和盆腔则很少受影响。我们报告了一例 40 岁患者的病例,该患者 15 年前曾因脑和宫颈包虫囊肿接受过手术,后因全身粘膜黄疸住院治疗。探查时,我们发现腹腔存在播散性包虫病,并伴有 3 个罕见部位:纵隔、胰腺和盆腔。间接诊断测试呈阳性:间接血凝(IHA)和 Elisa。Western 印迹检测也显示存在特异性条带,因此可以继续诊断为包虫病。位于纵膈、胰腺和盆腔的包虫囊肿非常罕见,它们之间的关联也非常特殊。在地方病流行地区的患者出现任何囊性病变时,都必须考虑到包虫起源。
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引用次数: 0
New Topical Treatment for Atopic Dermatitis 特应性皮炎的新型外用疗法
Pub Date : 2024-04-04 DOI: 10.24018/ejmed.2024.6.2.2067
José Miguel Ingelmo Calvo, José Ruiz Cobo, M. Allam
The primary approach for managing atopic dermatitis (AD) involves the use of topical corticosteroids as the first-line treatment.While high-potency topical corticosteroids have shown to be effective, they come with an increased risk of local and, rarely, systemic adverse effects. Additionally, patients often experience a relapsing and remitting course. A revolutionary topical treatment for psoriasis and AD has recently received patent approval from the Spanish Ministry of Industry, Trade, and Tourism. This innovative treatment, presented in the form of a lotion, includes a combination of clobetasol, papaverine hydrochloride, spironolactone, a milk-peptide complex, and propylene glycol. An 18-year-old female presented with AD on the back of her neck and scalp. The patient had no significant past medical history and primarily complained of intense pruritus in the AD lesions. The patient received guidance to apply our recently patented lotion, Psorisbye, once a day for 5 days. In total, 50 ml of Psorisbye was utilized over 4 days. On the fifth day, the patient underwent an examination at the outpatient clinic. The patient reported a significant improvement in pruritus sensations and observed a reduction in scaled lesions. Upon evaluating our patient, a comparison of the lesions before and after applying the topical treatment for 4 days revealed a notable improvement in the SCORAD index, decreasing from 49.95 to 0. While the results of Psorisbye in this case show promise, it is crucial to conduct further studies with larger sample sizes and extended follow-up periods to validate the findings presented in our case report.
治疗特应性皮炎(AD)的主要方法是将外用皮质类固醇激素作为一线治疗手段。虽然高浓度外用皮质类固醇激素已被证明是有效的,但它们会增加局部不良反应的风险,在极少数情况下还会增加全身不良反应的风险。此外,患者通常会经历复发和缓解的过程。最近,西班牙工业、贸易和旅游部批准了一种治疗银屑病和 AD 的革命性局部疗法的专利。这种创新的治疗方法以乳液的形式出现,包括氯倍他索、盐酸木瓜碱、螺内酯、牛奶肽复合物和丙二醇的组合。一名 18 岁的女性颈部和头皮后部出现 AD。患者既往无重大病史,主要诉说 AD 病变部位剧烈瘙痒。在我们的指导下,患者使用了我们最近获得专利的洗剂 Psorisbye,每天一次,连续使用 5 天。4 天共使用了 50 毫升 Psorisbye。第五天,患者在门诊接受了检查。患者表示瘙痒感明显好转,鳞屑也有所减少。在对患者进行评估后,对比使用外用药 4 天前后的皮损情况发现,SCORAD 指数有了明显改善,从 49.95 降至 0。虽然 Psorisbye 在本病例中的治疗效果很好,但关键是要进行样本量更大、随访时间更长的进一步研究,以验证本病例报告中的研究结果。
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引用次数: 0
Organ Donation: A Necessary Social Obligation? 器官捐赠:必要的社会义务?
Pub Date : 2024-04-04 DOI: 10.24018/ejmed.2024.6.2.2082
Felix Cantarovich
One success of medicine has been to change the death of a human being for the life of a patient with terminal organ failure when organs such as the liver or lung are donated. These results of organ surgery and treatments, nevertheless, are accompanied by the maintenance of patients waiting lists, and deaths. Educational programs have made advances in popular knowledge. However, the data shows that society’s undefined attitude toward donation impacts the “organ shortage”. For example, the value of the slogan that qualifies donating as a gift is controversial today. Organ shortage requires an analysis of its persistence, as well as suggestions for its solution.
医学的一个成功之处是,当肝脏或肺脏等器官被捐献出来时,人的死亡可以换来末期器官衰竭病人的生命。然而,这些器官手术和治疗的成果也伴随着病人的等待和死亡。教育计划在普及知识方面取得了进展。然而,数据显示,社会对捐赠的不明确态度影响了 "器官短缺"。例如,将捐献作为一种礼物的口号的价值在今天还存在争议。器官短缺问题需要对其持续性进行分析,并提出解决建议。
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引用次数: 0
Refractive Lens Exchange after Implanted Collamer Lens: A Case Report 植入 Collamer 透镜后的屈光晶体交换:病例报告
Pub Date : 2024-04-03 DOI: 10.24018/ejmed.2024.6.2.2063
Cokorda Istri, Dewiyani Pemayun, I. Gusti, Ngurah Agung, Wisnu Kresnan, Jelly Vianti, Fransisca Oeiyano
Introduction: Myopia stands as a prevalent ametropic condition. Posing ongoing challenges for ophthalmologists. Surgery to correct refractive errors is a primary intervention for severe myopia, encompassing procedures like the removal of the crystalline lens coupled with the placement of an intraocular lens (IOL), and the insertion of phakic IOL. The Implantable Collamer Lens (ICL) is commonly utilized in the posterior chamber but carries potential risks including the disruption of the eye’s normal function, potentially leading to conditions like cataracts and glaucoma.Methods and Purpose: This case report explains a single case patient with ICL that includes previous clinical condition, current condition, steps of surgical procedure, and follow-up after procedure.Case Illustration: We present the case of a 66-year-old male patient who came to the hospital for refractive surgery due to a cataract with a history of implantable collamer lens (ICL) for high myopia. Cataract surgery was performed after an explanation of the ICL followed by an implanted capsular tension ring (CTR) and IOL.Discussion: Several cases of patients using ICL will have complications such as glaucoma and cataracts. Determining ICL design will influence the progression of these complications. An explanation procedure by tuck and pull method is needed for age-related cataract patients.Conclusion: ICL is a safe procedure for high myopia patients. Explanation of ICL can be performed by several medical conditions.
导言近视是一种普遍的弱视。给眼科医生带来了持续的挑战。手术矫正屈光不正是治疗重度近视的主要方法,包括摘除晶状体、植入眼内人工晶体(IOL)和植入虹膜人工晶体等手术。植入式人工晶体(ICL)通常用于后房,但也有潜在风险,包括破坏眼睛的正常功能,可能导致白内障和青光眼等疾病。方法和目的:本病例报告解释了一例植入式人工晶体的患者,包括之前的临床状况、目前的状况、手术步骤和术后随访:本病例为一名 66 岁的男性患者,因白内障来院接受屈光手术,曾因高度近视接受过植入式准分子晶体(ICL)治疗。在对 ICL 进行解释后,进行了白内障手术,随后植入了晶体囊拉力环(CTR)和人工晶体:讨论:一些使用 ICL 的患者会出现青光眼和白内障等并发症。确定 ICL 的设计将影响这些并发症的发展。结论:ICL 是一种安全的手术,适合高发白内障患者:结论:对于高度近视患者来说,ICL是一种安全的手术。结论:对于高度近视患者来说,ICL 是一种安全的手术。
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引用次数: 0
Surgical Treatment of Supernumerary Elements for Orthodontic Purposes: Clinical Case Report 外科手术治疗用于正畸的赘生物:临床病例报告
Pub Date : 2024-04-01 DOI: 10.24018/ejmed.2024.6.2.2072
Vinicius da Silva De Oliveira, George Borja de Freitas, Wanderson Limeira de Sousa Barbosa, João Miguel da Silva Rebouças, Carla Graciele Santos, Ana Livia Casimiro De Oliveira, Aryelly de Mendonça Soares, Pedro Odon Almeida Silva, Tereza Raquel Vilar De Souza, Virna Taíse de Oliveira, Julierme Ferreira Rocha
Introduction: Hyperdontia is a type of dental development disorder linked to various factors, characterized by an excessive number of teeth in relation to the normal dental formula. This anomaly can affect both jaws and dentitions, but the anterior maxillary region and the permanent dentition are the most affected, and it is more prevalent in male patients. Early diagnosis and immediate treatment are of the utmost importance to avoid complications.Objective: To describe a surgical procedure involving the removal of bilateral mandibular supernumerary teeth in a 17-year-old patient for orthodontic purposes.Materials and Methods: This is a descriptive study of a clinical case, carried out by a student and a team of professors from the postgraduate course in minor oral surgery, at the Dentistry school clinic of the Integrated College of Patos (UNIFIP). The procedure was carried out in two surgical procedures, with a 30-day interval between the surgeries.Conclusion: There are several consequences that supernumerary elements can cause and this case report raises awareness and provides evidence for the clinical characterization and optimal treatment of supernumerary teeth.
导言:牙列畸形是一种与各种因素有关的牙齿发育障碍,其特点是与正常牙列相比,牙齿数量过多。这种畸形可影响颌骨和牙列,但上颌前区和恒牙列受影响最大,男性患者发病率更高。早期诊断和及时治疗对避免并发症至关重要:描述在一名 17 岁患者中为正畸目的拔除双侧下颌多余牙齿的手术过程:这是一项临床病例的描述性研究,由帕托斯综合学院(UNIFIP)口腔医学院诊所的一名学生和口腔小手术研究生课程的教授团队共同完成。手术分两次进行,每次手术间隔 30 天:本病例报告提高了人们对超常牙的认识,并为超常牙的临床特征和最佳治疗提供了证据。
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引用次数: 0
期刊
European Journal of Medical and Health Sciences
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