Pub Date : 2024-01-20DOI: 10.12775/jehs.2024.54.011
Zuzanna Olejarz, Karolina Nowak, Zuzanna Drygała, Julia Wyrwał, Zuzanna Zielińska, Magdalena Słowik, Karolina Nowak, Maria Nieć, Katarzyna Gierlach, Martyna Krasuska
Introduction and purpose: Acute mountain sickness is caused by hypoxia, of which the brain is the most sensitive. The frequency of occurrence at altitudes above 2500 m above sea level may reach up to 75% of travelers. Prevention of altitude sickness mainly concerns the travel plan and pharmacology. Our study aimed to assess the current literature on altitude sickness, and discuss the possible pathophysiology, epidemiology, and symptoms. Moreover, we underline new guidelines for the treatment, prevention, and diagnosis of altitude sickness in the context of the last guidelines and research. We conducted a PubMed literature review using keywords like "mountaineering sickness" and "altitude sickness". All article types were taken into account: clinical trial, meta-analysis, case report, case series, systematic review, randomized controlled trial, observational study, clinical study, books, and documents in the last 5 years.A brief description of the state of knowledge: In recent years, there has been a surge in the accessibility and popularity of high-altitude tourism, emphasizing the need to disseminate information about altitude sickness among travelers. This heightened accessibility has sparked a push for comprehensive research and viable solutions, aiming to address the ramifications of the increased risk associated with such endeavors. Furthermore, there's a growing call for additional research focusing on the unique medical demands posed by tourist excursions and extreme expeditions. Conclusions:It underscores the necessity for healthcare professionals equipped with specialized knowledge and expertise in both preventing and treating medical conditions arising in exceptional circumstances.
{"title":"Examination of novel diagnostic approaches and contemporary strategies for preventing acute mountain sickness","authors":"Zuzanna Olejarz, Karolina Nowak, Zuzanna Drygała, Julia Wyrwał, Zuzanna Zielińska, Magdalena Słowik, Karolina Nowak, Maria Nieć, Katarzyna Gierlach, Martyna Krasuska","doi":"10.12775/jehs.2024.54.011","DOIUrl":"https://doi.org/10.12775/jehs.2024.54.011","url":null,"abstract":"Introduction and purpose: Acute mountain sickness is caused by hypoxia, of which the brain is the most sensitive. The frequency of occurrence at altitudes above 2500 m above sea level may reach up to 75% of travelers. Prevention of altitude sickness mainly concerns the travel plan and pharmacology. Our study aimed to assess the current literature on altitude sickness, and discuss the possible pathophysiology, epidemiology, and symptoms. Moreover, we underline new guidelines for the treatment, prevention, and diagnosis of altitude sickness in the context of the last guidelines and research. We conducted a PubMed literature review using keywords like \"mountaineering sickness\" and \"altitude sickness\". All article types were taken into account: clinical trial, meta-analysis, case report, case series, systematic review, randomized controlled trial, observational study, clinical study, books, and documents in the last 5 years.A brief description of the state of knowledge: In recent years, there has been a surge in the accessibility and popularity of high-altitude tourism, emphasizing the need to disseminate information about altitude sickness among travelers. This heightened accessibility has sparked a push for comprehensive research and viable solutions, aiming to address the ramifications of the increased risk associated with such endeavors. Furthermore, there's a growing call for additional research focusing on the unique medical demands posed by tourist excursions and extreme expeditions. Conclusions:It underscores the necessity for healthcare professionals equipped with specialized knowledge and expertise in both preventing and treating medical conditions arising in exceptional circumstances.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"2 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139524677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-20DOI: 10.12775/jehs.2024.54.009
Martyna Kępczyk, Oliwia Kwaśniewska, Jakub Misiak, Michał Urbaś, Miłosz Ojdana, Yehor Demianenko, Oliwia Czekaj, Aleksandra Kościołek, Dawid Kościołek, Kaja Surowiecka
INTRODUCTION AND AIM OF WORK Stress often accompanies daily functioning. This mechanism is activated by the body in response to external factors to effectively cope with challenges. With prolonged exposure, stress significantly impairs physiological functions, including impacting body weight. MATERIALS AND METHODS The aim of the study is to understand the impact of chronic stress on changes in dietary habits and body weight. For this purpose, a custom survey was created to investigate the correlation between stress and other factors. It was distributed using social media (Telegram) in the first half of August 2023 among the population of Ukraine. RESULTS The survey was completed by 110 individuals, with the majority being males, accounting for 67 participants (61%). The participants had an average age of 28 years with a standard deviation of 7.12. Among the responses, the most common frequency of experiencing stress was once every two weeks, with 41 answers (37.27% of participants). A majority of the respondents declared having a normal body weight (55.45%). In our study, we demonstrated a correlation between stress and unhealthy eating habits (rho-Spearman p=0.0002, r=0.34), as well as a lower frequency of stress among individuals taking antidepressant medication (p=0.012). However, we did not establish a connection with abnormal body weight (p>0.05), physical activity (p>0.05), or healthy eating (p>0.05). CONCLUSIONS The obtained results suggest that stress may trigger a response in the form of overeating. The reduction in the frequency of stress is also influenced by the use of medications. The findings may indicate a strong association between diet and the experience of stress.
{"title":"Chronic stress and its relationship with increased food consumption and the risk of obesity","authors":"Martyna Kępczyk, Oliwia Kwaśniewska, Jakub Misiak, Michał Urbaś, Miłosz Ojdana, Yehor Demianenko, Oliwia Czekaj, Aleksandra Kościołek, Dawid Kościołek, Kaja Surowiecka","doi":"10.12775/jehs.2024.54.009","DOIUrl":"https://doi.org/10.12775/jehs.2024.54.009","url":null,"abstract":"INTRODUCTION AND AIM OF WORK \u0000Stress often accompanies daily functioning. This mechanism is activated by the body in response to external factors to effectively cope with challenges. With prolonged exposure, stress significantly impairs physiological functions, including impacting body weight. \u0000MATERIALS AND METHODS \u0000The aim of the study is to understand the impact of chronic stress on changes in dietary habits and body weight. For this purpose, a custom survey was created to investigate the correlation between stress and other factors. It was distributed using social media (Telegram) in the first half of August 2023 among the population of Ukraine. \u0000RESULTS \u0000The survey was completed by 110 individuals, with the majority being males, accounting for 67 participants (61%). The participants had an average age of 28 years with a standard deviation of 7.12. Among the responses, the most common frequency of experiencing stress was once every two weeks, with 41 answers (37.27% of participants). A majority of the respondents declared having a normal body weight (55.45%). \u0000In our study, we demonstrated a correlation between stress and unhealthy eating habits (rho-Spearman p=0.0002, r=0.34), as well as a lower frequency of stress among individuals taking antidepressant medication (p=0.012). However, we did not establish a connection with abnormal body weight (p>0.05), physical activity (p>0.05), or healthy eating (p>0.05). \u0000CONCLUSIONS \u0000The obtained results suggest that stress may trigger a response in the form of overeating. The reduction in the frequency of stress is also influenced by the use of medications. The findings may indicate a strong association between diet and the experience of stress.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"37 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139610224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-20DOI: 10.12775/jehs.2024.54.010
Katarzyna Wiejak, Kinga Przyborowska, Michał Łata, Beata Getka, Justyna Kwiecień, Mateusz Rukat, Agnieszka Strojny
Introduction: In the knee joint are two menisci, which are fibrocartilaginous structures. The tears of the meniscus are one of the most common injuries within knee. Arthroscopy with suturing of torn or menisectomy are the most popular methods of treatment, however in long term observation menisectomy often results in osteoarthritis 10-20 years after surgery. For this reason, less invasive treatment methods are being sought, such as platelet-rich plasma injections. Platelet-rich plasma has many growth factors, which stimulates healing. Objective: The aim of this study is to review latest the literature on the use of platelet-rich plasma injections in the patients with meniscus tears. Material and methods: A literature review was conducted on databases such as PubMed and Google Scholar using the terms: ”meniscus”, “meniscus tear”, “platelet-rich plasma”, “platelet-rich plasma injections”, “meniscus injuries treatment’. Conclusions: The injuries of meniscus are very common, and often must be treated by arthroscopy. Platelet-rich plasma has a positive impact on tissue healing. Platelet-rich plasma injuries in the patients with meniscal tears repair lead to improve healing rates compare with patients without PRP injections, but there is no guidelines and further studies are necessary.
简介膝关节内有两个半月板，它们是纤维软骨结构。半月板撕裂是膝关节最常见的损伤之一。关节镜手术缝合撕裂的半月板或半月板切除术是最常用的治疗方法，但在长期观察中，半月板切除术往往会导致术后 10-20 年出现骨关节炎。因此，人们开始寻求创伤较小的治疗方法，如注射富血小板血浆。富血小板血浆含有多种生长因子，可刺激伤口愈合：本研究旨在回顾有关半月板撕裂患者使用富血小板血浆注射的最新文献：在 PubMed 和 Google Scholar 等数据库中使用以下术语进行了文献综述：半月板"、"半月板撕裂"、"富血小板血浆"、"富血小板血浆注射"、"半月板损伤治疗"：结论：半月板损伤非常常见，通常必须通过关节镜进行治疗。富血小板血浆对组织愈合有积极影响。与未注射 PRP 的患者相比，在半月板撕裂修复患者中注射富血小板血浆可提高愈合率，但目前尚无相关指南，有必要开展进一步研究。
{"title":"The use of platelet-rich plasma injections in the treatment of meniscal injuries - review of the literature","authors":"Katarzyna Wiejak, Kinga Przyborowska, Michał Łata, Beata Getka, Justyna Kwiecień, Mateusz Rukat, Agnieszka Strojny","doi":"10.12775/jehs.2024.54.010","DOIUrl":"https://doi.org/10.12775/jehs.2024.54.010","url":null,"abstract":"Introduction: In the knee joint are two menisci, which are fibrocartilaginous structures. The tears of the meniscus are one of the most common injuries within knee. Arthroscopy with suturing of torn or menisectomy are the most popular methods of treatment, however in long term observation menisectomy often results in osteoarthritis 10-20 years after surgery. For this reason, less invasive treatment methods are being sought, such as platelet-rich plasma injections. Platelet-rich plasma has many growth factors, which stimulates healing.\u0000Objective: The aim of this study is to review latest the literature on the use of platelet-rich plasma injections in the patients with meniscus tears.\u0000Material and methods: A literature review was conducted on databases such as PubMed and Google Scholar using the terms: ”meniscus”, “meniscus tear”, “platelet-rich plasma”, “platelet-rich plasma injections”, “meniscus injuries treatment’.\u0000Conclusions: The injuries of meniscus are very common, and often must be treated by arthroscopy. Platelet-rich plasma has a positive impact on tissue healing. Platelet-rich plasma injuries in the patients with meniscal tears repair lead to improve healing rates compare with patients without PRP injections, but there is no guidelines and further studies are necessary.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"3 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139524096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-20DOI: 10.12775/jehs.2024.54.008
Mateusz Kobierecki, Oliwia Kwaśniewska, Jakub Misiak, Michał Urbaś, Miłosz Ojdana, Yehor Demianenko, Oliwia Czekaj, Aleksandra Kościołek, Dawid Kościołek, Martyna Kępczyk
INTRODUCTION AND AIM OF WORK One of the key factors shaping human health is diet. It serves as the foundation for the functioning of cells, organs, and the entire body. Properly chosen food has an impact, among other things, on the functioning of the immune, digestive, and cardiovascular systems. MATERIALS AND METHODS The objective of this study is to analyze the changes in the functioning of the cardiovascular, digestive, and immune systems through the application of different dietary approaches. For this purpose, an original questionnaire was developed. The questionnaire was distributed via social media (Telegram platform) in August 2023 among the population of Ukraine. RESULTS We collected a total of 94 surveys, with an average participant age of 26 years. A similar number of participants indicated consuming meals 3 times, 4 times, or 5 times a day. These were 23 individuals (24.47%), 25 individuals (26.6%), and 21 individuals (22.3%) respectively. The analysis of correlations revealed a negative correlation between the frequency of meal consumption and the frequency of infections (r = -0.21, p = 0.035). A significant relationship was also observed between body weight and the frequency of meal consumption (r = 0.34, p < 0.001). However, no significant relationship was found between following a special diet and body weight (p > 0.05). CONCLUSIONS The collected results suggest a connection between dietary habits and the frequency of infections as well as body weight. Interestingly, this relationship was related specifically to the frequency of meal consumption and was not linked to the intake of specific food groups. The obtained results highlight the significance of regular meal consumption in maintaining a healthy body weight and reducing the frequency of infections.
{"title":"The Impact of diet on the digestive, cardiovascular and immune systems","authors":"Mateusz Kobierecki, Oliwia Kwaśniewska, Jakub Misiak, Michał Urbaś, Miłosz Ojdana, Yehor Demianenko, Oliwia Czekaj, Aleksandra Kościołek, Dawid Kościołek, Martyna Kępczyk","doi":"10.12775/jehs.2024.54.008","DOIUrl":"https://doi.org/10.12775/jehs.2024.54.008","url":null,"abstract":"INTRODUCTION AND AIM OF WORK \u0000One of the key factors shaping human health is diet. It serves as the foundation for the functioning of cells, organs, and the entire body. Properly chosen food has an impact, among other things, on the functioning of the immune, digestive, and cardiovascular systems. \u0000 \u0000MATERIALS AND METHODS \u0000The objective of this study is to analyze the changes in the functioning of the cardiovascular, digestive, and immune systems through the application of different dietary approaches. For this purpose, an original questionnaire was developed. The questionnaire was distributed via social media (Telegram platform) in August 2023 among the population of Ukraine. \u0000 \u0000RESULTS \u0000We collected a total of 94 surveys, with an average participant age of 26 years. A similar number of participants indicated consuming meals 3 times, 4 times, or 5 times a day. These were 23 individuals (24.47%), 25 individuals (26.6%), and 21 individuals (22.3%) respectively. The analysis of correlations revealed a negative correlation between the frequency of meal consumption and the frequency of infections (r = -0.21, p = 0.035). A significant relationship was also observed between body weight and the frequency of meal consumption (r = 0.34, p < 0.001). However, no significant relationship was found between following a special diet and body weight (p > 0.05). \u0000 \u0000CONCLUSIONS \u0000The collected results suggest a connection between dietary habits and the frequency of infections as well as body weight. Interestingly, this relationship was related specifically to the frequency of meal consumption and was not linked to the intake of specific food groups. The obtained results highlight the significance of regular meal consumption in maintaining a healthy body weight and reducing the frequency of infections.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"18 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139610762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction and purpose Congenital Cytomegalovirus (CMV) infection stands as the prevalent infection among newborns and it may be associated with later complications such as progressive sensorineural hearing loss or neurological diseases. Infection occurs during pregnancy or during childbirth. Congenital CMV infections manifest in various ways, ranging from asymptomatic cases to severe complications such as microcephaly, hepatosplenomegaly, and chorioretinitis. Routine antibody screenings for pregnant women are not common, underlining the significance of early infection detection to minimize the risks of transmission to the fetus and potential complications in the child. The aim of this case report is to present the course of congenital CMV infection and its complication. This case report explores the challenges of managing an infant with congenital CMV infection complicated by hydrocephalus and viral co-infections. The infant underwent various treatments, including antiviral therapy, highlighting the need for multidisciplinary approaches. Conclusion With no available vaccine, prevention of congenital CMV infection relies on educating reproductive-age women and expectant mothers about infection risks. Early detection, frequent medical check-ups, and preventive education are crucial due to the absence of vaccines. Ongoing exploration of antiviral treatments and prompt interventions is imperative to improve outcomes for infants and families affected by the virus.
{"title":"Congenital CMV Infection: A Complex Case of Neurological Complications and Therapeutic Approaches in Infancy","authors":"Sylwia Koziej, Emilia Kowalczyk, Martyna Niemczuk, Adrianna Jasiuk, Mateusz Wiekiera","doi":"10.12775/jehs.2024.54.012","DOIUrl":"https://doi.org/10.12775/jehs.2024.54.012","url":null,"abstract":"Introduction and purpose \u0000Congenital Cytomegalovirus (CMV) infection stands as the prevalent infection among newborns and it may be associated with later complications such as progressive sensorineural hearing loss or neurological diseases. Infection occurs during pregnancy or during childbirth. Congenital CMV infections manifest in various ways, ranging from asymptomatic cases to severe complications such as microcephaly, hepatosplenomegaly, and chorioretinitis. Routine antibody screenings for pregnant women are not common, underlining the significance of early infection detection to minimize the risks of transmission to the fetus and potential complications in the child. \u0000The aim of this case report is to present the course of congenital CMV infection and its complication. This case report explores the challenges of managing an infant with congenital CMV infection complicated by hydrocephalus and viral co-infections. The infant underwent various treatments, including antiviral therapy, highlighting the need for multidisciplinary approaches. \u0000Conclusion \u0000 With no available vaccine, prevention of congenital CMV infection relies on educating reproductive-age women and expectant mothers about infection risks. Early detection, frequent medical check-ups, and preventive education are crucial due to the absence of vaccines. Ongoing exploration of antiviral treatments and prompt interventions is imperative to improve outcomes for infants and families affected by the virus.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"10 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139524417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mitral valve prolapse is a common valvular defect. In its overt clinical form, the condition known as mitral valve leaflet prolapse syndrome, or also known as Barlow's syndrome or flaccid valve syndrome, is a significant clinical problem, worsening the quality of life of patients, and in its severe forms is a risk factor for diseases such as congestive heart failure, endocarditis or cardiac arrhythmias, or even lead to death from sudden cardiac death. The development of methods, as well as the increasing general availability of echocardiography methods, makes a specific diagnosis early enough to allow the right treatment strategy to be chosen. Thanks to reliable reports in recent years, it has been possible to identify a group of patients whose cardiovascular risk predisposes them to a more severe course of the disease and thus these patients require special observation and attention in the process of diagnosis and treatment. Recent years have allowed the development of a new method of interventional treatment in patients burdened with multimorbidity for whom conventional surgery would be associated with a significant risk of worsening of the general condition.
{"title":"Mitral valve prolapse syndrome","authors":"Miłosz Sanecki, Karolina Jurasz, Dominika Podgórska, Karolina Tomczyk, Natalia Chojnacka, Ewa Rzeska, Jakub Klarycki, Radosław Cymer","doi":"10.12775/jehs.2024.53.013","DOIUrl":"https://doi.org/10.12775/jehs.2024.53.013","url":null,"abstract":"Mitral valve prolapse is a common valvular defect. In its overt clinical form, the condition known as mitral valve leaflet prolapse syndrome, or also known as Barlow's syndrome or flaccid valve syndrome, is a significant clinical problem, worsening the quality of life of patients, and in its severe forms is a risk factor for diseases such as congestive heart failure, endocarditis or cardiac arrhythmias, or even lead to death from sudden cardiac death. \u0000The development of methods, as well as the increasing general availability of echocardiography methods, makes a specific diagnosis early enough to allow the right treatment strategy to be chosen. \u0000Thanks to reliable reports in recent years, it has been possible to identify a group of patients whose cardiovascular risk predisposes them to a more severe course of the disease and thus these patients require special observation and attention in the process of diagnosis and treatment. \u0000Recent years have allowed the development of a new method of interventional treatment in patients burdened with multimorbidity for whom conventional surgery would be associated with a significant risk of worsening of the general condition. \u0000","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139524183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-19DOI: 10.12775/jehs.2024.53.015
Jakub Misiak, Martyna Kępczyk, Oliwia Kwaśniewska, Michał Urbaś, Miłosz Ojdana, Yehor Demianenko, Oliwia Czekaj, Aleksandra Kościołek, Dawid Kościołek, Kaja Surowiecka
Introduction and purpose: Non-alcoholic fatty liver disease's growing prevalence and the complications it brings constitutes a serious problem nowadays. According to this, better understanding of mechanisms laying on the ground of its pathogenesis is a crucial factor to better understand this disease and develop interventions to counter its effects. Genetic relationships with NAFLD are known and they show great variation of mechanisms underlying their impact on subjects' metabolic state. Due to this fact the assumption that it is worth collecting these connections in one place was made, so that it is easier to navigate in them. Mostly studies refer to rodents trials, we focused on studies referred to people with NAFLD diagnosis. Material and method: The literature was scrutinised in the Google Scholar database, in the Pubmed database with the use of following keywords: “genetics”, “genes”, “non-alcoholic fatty liver disease”, “NAFLD”, “non-alcoholic steatohepatitis”, “NASH”. Results: NAFLD as a metabolic disease has many links with metabolic pathways encoded by various genes. When it comes to genetic factors, we can specify gene expression single nucleotide polymorphisms (SNP) and genes methylation. All of these aspects affect activity of coded proteins and what follows this is its impact on human metabolism. These factors have been studied in the work of other researchers. Conclusions: Non-alcoholic fatty liver disease's growing prevalence and the complications it brings constitutes a serious problem nowadays. Genetic relationships with NAFLD are known and they show great variation of mechanisms underlying their impact on subjects' metabolic state.
{"title":"Genetic implications in patients with NAFLD","authors":"Jakub Misiak, Martyna Kępczyk, Oliwia Kwaśniewska, Michał Urbaś, Miłosz Ojdana, Yehor Demianenko, Oliwia Czekaj, Aleksandra Kościołek, Dawid Kościołek, Kaja Surowiecka","doi":"10.12775/jehs.2024.53.015","DOIUrl":"https://doi.org/10.12775/jehs.2024.53.015","url":null,"abstract":"Introduction and purpose:\u0000Non-alcoholic fatty liver disease's growing prevalence and the complications it brings constitutes a serious problem nowadays. According to this, better understanding of mechanisms laying on the ground of its pathogenesis is a crucial factor to better understand this disease and develop interventions to counter its effects. Genetic relationships with NAFLD are known and they show great variation of mechanisms underlying their impact on subjects' metabolic state. Due to this fact the assumption that it is worth collecting these connections in one place was made, so that it is easier to navigate in them. Mostly studies refer to rodents trials, we focused on studies referred to people with NAFLD diagnosis.\u0000Material and method: \u0000The literature was scrutinised in the Google Scholar database, in the Pubmed database with the use of following keywords: “genetics”, “genes”, “non-alcoholic fatty liver disease”, “NAFLD”, “non-alcoholic steatohepatitis”, “NASH”.\u0000Results:\u0000NAFLD as a metabolic disease has many links with metabolic pathways encoded by various genes. When it comes to genetic factors, we can specify gene expression single nucleotide polymorphisms (SNP) and genes methylation. All of these aspects affect activity of coded proteins and what follows this is its impact on human metabolism. These factors have been studied in the work of other researchers.\u0000Conclusions:\u0000 Non-alcoholic fatty liver disease's growing prevalence and the complications it brings constitutes a serious problem nowadays. Genetic relationships with NAFLD are known and they show great variation of mechanisms underlying their impact on subjects' metabolic state.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"15 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139613634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-19DOI: 10.12775/jehs.2024.54.004
Dawid Burek, Aleksandra Paszkowska, Aleksandra Kujawa, Urszula Matuszewska, Aleksandra Nykowska, Katarzyna Beutler, Bartosz Bijata
Introduction Anemia and iron deficiency are common comorbidities in population with heart failure. Their association with unfavorable prognostic outcomes and diminished quality of life underscores the imperative need for accurate diagnosis and efficacious treatment interventions. In recent years numerous treatment options have been explored in clinical trials, aimed at addressing the multifaced aspects of these concurrent conditions. Summary In patients with heart failure effective treatment of anemia and iron deficiency has demonstrated enhancements in quality of life and exercise capacity. Findings from IRONMAN clinical study have prompted revisions in the latest guidelines from the European Society of Cardiology. The imminent release of results from two ongoing trials holds the potential to reshape the therapeutic landscape for treating individuals with heart failure and iron deficiency. Nevertheless, there is no explicit evidence that studied interventions could improve morbidity or risk of hospitalizations.
{"title":"Anemia amongst patients with heart failure - a review","authors":"Dawid Burek, Aleksandra Paszkowska, Aleksandra Kujawa, Urszula Matuszewska, Aleksandra Nykowska, Katarzyna Beutler, Bartosz Bijata","doi":"10.12775/jehs.2024.54.004","DOIUrl":"https://doi.org/10.12775/jehs.2024.54.004","url":null,"abstract":"Introduction \u0000Anemia and iron deficiency are common comorbidities in population with heart failure. Their association with unfavorable prognostic outcomes and diminished quality of life underscores the imperative need for accurate diagnosis and efficacious treatment interventions. In recent years numerous treatment options have been explored in clinical trials, aimed at addressing the multifaced aspects of these concurrent conditions. \u0000Summary \u0000In patients with heart failure effective treatment of anemia and iron deficiency has demonstrated enhancements in quality of life and exercise capacity. Findings from IRONMAN clinical study have prompted revisions in the latest guidelines from the European Society of Cardiology. The imminent release of results from two ongoing trials holds the potential to reshape the therapeutic landscape for treating individuals with heart failure and iron deficiency. Nevertheless, there is no explicit evidence that studied interventions could improve morbidity or risk of hospitalizations.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"4 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139525214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-19DOI: 10.12775/jehs.2024.54.003
Michał Głodzik, Marek Miśkiewicz, Martyna Łęcka, Aleksandra Ogiegło-Kowalczyk, Julia Samborska, Karina Stelmaszak, Katarzyna Stencel, Paweł Więckowiak, Monika Wojtasik, Katarzyna Żak
The main aim of the following study is to review current knowledge on Influenza. Influenza, also known as the flu, is an acute, infectious disease which attacks the respiratory system. The disease is caused by the influenza virus, of which there are 3 types. The most common is type A of influenza virus. It is transmitted between people by the droplet route, with cases occurring particularly frequently during seasonal epidemics. This is why the most important form of prevention is maintaining personal hygiene and isolation of sick people. Another form of prevention is a vaccine for the influenza virus developed with new variants every year. The flu causes a variety of symptoms from many systems but can also be asymptomatic. Diagnosis of the illness is based on clinical criteria and the results of diagnostic tests for which there are established criteria of legitimacy. Most common and sufficient curation for an illness is a symptomatic treatment but there is also a causal treatment for influenza. However certain conditions are required for its implementation. Influenza is usually a mild disease, but there are present cases of serious complications. Groups particularly exposed to severe and complicated courses of the disease are pregnant women, children and patients with multimorbidities. Currently, the co-occurrence of influenza with Covid-19 infection is particularly dangerous, which constitutes a new challenge for the global health care system.
{"title":"Clinical management and supervision of Influenza – systematic review","authors":"Michał Głodzik, Marek Miśkiewicz, Martyna Łęcka, Aleksandra Ogiegło-Kowalczyk, Julia Samborska, Karina Stelmaszak, Katarzyna Stencel, Paweł Więckowiak, Monika Wojtasik, Katarzyna Żak","doi":"10.12775/jehs.2024.54.003","DOIUrl":"https://doi.org/10.12775/jehs.2024.54.003","url":null,"abstract":"The main aim of the following study is to review current knowledge on Influenza. \u0000Influenza, also known as the flu, is an acute, infectious disease which attacks the respiratory system. The disease is caused by the influenza virus, of which there are 3 types. The most common is type A of influenza virus. It is transmitted between people by the droplet route, with cases occurring particularly frequently during seasonal epidemics. This is why the most important form of prevention is maintaining personal hygiene and isolation of sick people. Another form of prevention is a vaccine for the influenza virus developed with new variants every year. The flu causes a variety of symptoms from many systems but can also be asymptomatic. Diagnosis of the illness is based on clinical criteria and the results of diagnostic tests for which there are established criteria of legitimacy. Most common and sufficient curation for an illness is a symptomatic treatment but there is also a causal treatment for influenza. However certain conditions are required for its implementation. Influenza is usually a mild disease, but there are present cases of serious complications. Groups particularly exposed to severe and complicated courses of the disease are pregnant women, children and patients with multimorbidities. Currently, the co-occurrence of influenza with Covid-19 infection is particularly dangerous, which constitutes a new challenge for the global health care system. ","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139526085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-19DOI: 10.12775/jehs.2024.54.005
Katarzyna Stencel, Karina Stelmaszak, Monika Wojtasik, Aleksandra Ogiegło-Kowalczyk, Julia Samborska, Paweł Więckowiak, Michał Głodzik, Marek Miśkiewicz, Martyna Łęcka, Katarzyna Żak
Rhinophyma is defined as a progressive, deforming, nodular enlargement of the sebaceous glands caused by hypertrophy of the sebaceous follicles. It is assumed to be the final phase of chronic rosacea occurring mainly in Caucasian men. This disease negatively affects the quality of life of patients due to decreased self-esteem and depressive disorders. Nasal deformation by narrowing the nostrils impairs the physical performance of patients and even leads to the development of sleep apnea. Treatment is mainly based on surgery to remove pathological tissue. The literature also provides the possibility of therapy using ablative techniques and laser therapy.
{"title":"Rhinophyma - the end-stage of rosacea","authors":"Katarzyna Stencel, Karina Stelmaszak, Monika Wojtasik, Aleksandra Ogiegło-Kowalczyk, Julia Samborska, Paweł Więckowiak, Michał Głodzik, Marek Miśkiewicz, Martyna Łęcka, Katarzyna Żak","doi":"10.12775/jehs.2024.54.005","DOIUrl":"https://doi.org/10.12775/jehs.2024.54.005","url":null,"abstract":"Rhinophyma is defined as a progressive, deforming, nodular enlargement of the sebaceous glands caused by hypertrophy of the sebaceous follicles. It is assumed to be the final phase of chronic rosacea occurring mainly in Caucasian men. This disease negatively affects the quality of life of patients due to decreased self-esteem and depressive disorders. Nasal deformation by narrowing the nostrils impairs the physical performance of patients and even leads to the development of sleep apnea. Treatment is mainly based on surgery to remove pathological tissue. The literature also provides the possibility of therapy using ablative techniques and laser therapy. \u0000 ","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139524940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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