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Medicare Advantage in Total Knee Arthroplasty: No Difference in 1-year Outcomes Among 7,267 Total Knee Arthroplasty Patients. 全膝关节置换术的医疗优势:7267例全膝关节置换术患者1年预后无差异。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-24 DOI: 10.5435/JAAOS-D-25-00841
Benjamin E Jevnikar, Khaled A Elmenawi, Yuxuan Jin, Shujaa T Khan, Ignacio Pasqualini, Nicolas S Piuzzi

Background: Medicare advantage (MA) enrollment is rising rapidly, now comprising over half of all Medicare beneficiaries. Compared with traditional medicare (TM), MA patients are more likely to be socioeconomically disadvantaged and subject to distinct care coordination barriers, yet few studies have examined how these differences affect postoperative outcomes after total knee arthroplasty (TKA).

Methods: We analyzed a prospective cohort of 7,267 Medicare beneficiaries who underwent primary TKA at a high-volume academic center between 2016 and 2023. Patients were categorized MA or TM based on insurance status at the time of surgery. Primary outcomes included postoperative healthcare utilization: prolonged length of stay (≥2 days), nonhome discharge, 90-day readmission, 90-day emergency department visit, 1-year revision surgery, and 1-year mortality. Multivariable logistic regression models adjusted for demographic, clinical, and socioeconomic covariates.

Results: Of the cohort, 3,293 (45.3%) were MA and 3,974 (54.7%) were TM. MA patients were more likely to be non-White (17.7% vs. 10.2%, P < 0.001), have higher area deprivation index scores (49.0 vs. 42.0, P < 0.001), and higher smoking rates (6.1% vs. 4.0%, P < 0.001). Unadjusted rates of 90-day emergency department visits (16.8% vs. 14.6%, P = 0.011) and 1-year revision surgery (4.4% vs. 3.5%, P = 0.041) were higher in the MA group. However, after adjustment, MA status was not significantly associated with increased odds of any adverse outcome, including revision surgery (odds ratio, 0.85; 95% confidence interval, 0.66 to 1.08; P = 0.181) or mortality (odds ratio, 0.89; 95% confidence interval, 0.73 to 1.10; P = 0.285).

Conclusion: Despite greater baseline social risk, MA patients undergoing TKA at a high-volume academic center experienced comparable short-term outcomes with their TM counterparts. These findings suggest that when standardized care pathways are applied, Medicare subcategory alone does not predict postoperative healthcare utilization. As MA enrollment continues to grow, ensuring equitable outcomes will require adaptation of clinical workflows and research strategies to better reflect the evolving Medicare landscape.

背景:医疗保险优势(MA)注册人数正在迅速上升,现在占所有医疗保险受益人的一半以上。与传统医疗保险(TM)相比,MA患者更有可能处于社会经济劣势,并面临明显的护理协调障碍,但很少有研究调查这些差异如何影响全膝关节置换术(TKA)术后结果。方法:我们分析了2016年至2023年间在高容量学术中心接受初级TKA的7267名医疗保险受益人的前瞻性队列。根据手术时的保险状况将患者分为MA或TM。主要结局包括术后医疗保健利用:住院时间延长(≥2天)、非家庭出院、90天再入院、90天急诊科就诊、1年翻修手术和1年死亡率。多变量逻辑回归模型调整人口统计,临床和社会经济协变量。结果:队列中MA 3293例(45.3%),TM 3974例(54.7%)。MA患者非白种人(17.7% vs. 10.2%, P < 0.001)、区域剥夺指数评分较高(49.0 vs. 42.0, P < 0.001)、吸烟率较高(6.1% vs. 4.0%, P < 0.001)。MA组90天急诊就诊(16.8%比14.6%,P = 0.011)和1年翻修手术(4.4%比3.5%,P = 0.041)的未调整率更高。然而,调整后,MA状态与任何不良结局的发生率增加没有显著相关,包括翻修手术(优势比0.85;95%可信区间0.66 ~ 1.08;P = 0.181)或死亡率(优势比0.89;95%可信区间0.73 ~ 1.10;P = 0.285)。结论:尽管基线社会风险更高,但在大容量学术中心接受TKA的MA患者与TM患者的短期预后相当。这些发现表明,当采用标准化的护理途径时,单独的医疗保险亚类别不能预测术后医疗保健的利用。随着硕士入学人数的持续增长,确保公平的结果将需要适应临床工作流程和研究策略,以更好地反映不断变化的医疗保险格局。
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引用次数: 0
Liposomal Bupivacaine + Bupivacaine Versus Bupivacaine Interscalene Nerve Block Effect on Pain After Rotator Cuff Repair: A Randomized Control Trial. 布比卡因脂质体+布比卡因与布比卡因斜角肌间神经阻滞对肩袖修复术后疼痛的影响:一项随机对照试验。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-24 DOI: 10.5435/JAAOS-D-25-01002
Catherine J Fedorka, Haley N Tornberg, Christopher Rivera-Pintado, Pietro M Gentile, Devyn Russo, Michael Boniello, Krystal Hunter, Ronak Desai, Dhiren Soni, Matthew T Kleiner, Gregory Dodson

Background: Interscalene nerve blocks (ISB) are commonly used for perioperative pain control after shoulder arthroscopy. Bupivacaine has historically been the primary anesthetic used in ISBs. In 2018, the U.S. Food and Drug Administration approved liposomal bupivacaine for ISBs. This study aims to identify the effect of ISBs using bupivacaine alone (B) versus liposomal bupivacaine + bupivacaine (LBB) on postoperative pain control after arthroscopic rotator cuff repair (RCR).

Methods: A single-center, prospective, double-blinded, randomized, control trial following Consolidated Standards of Reporting guidelines was conducted from January 2020 to April 2024; 128 opiate naive patients undergoing arthroscopic RCR were randomized 1:1 into the B-only group (25 cc of 0.5% bupivacaine) versus the LBB group (133 mg [10 mL] of liposomal bupivacaine + 15 cc 0.5% bupivacaine). Demographics, comorbidities, additional procedures performed, daily morphine milligram equivalents (MME) consumed, and daily visual analog scale (VAS) pain scores for 14 days were collected.

Results: No differences were noted between age, sex, comorbidities, or American Society of Anesthesiologists physical classification system scores. On postoperative day 2, the LBB group consumed markedly lower MMEs (0.0 [0.0 to 7.5] versus 0.0 [0.0 to 15.0]; [P = 0.04]) and demonstrated a notable improvement in VAS scores on postoperative day 2 (4.8 ± 3.0 versus 6.0 ± 2.8; [P = 0.03]). No notable difference was seen in other daily MMEs consumed, daily VAS scores, or total 14-day MMEs. Total median MME consumed in both groups was low (MME 35.6 [7.5 to 88.1] or 5 [1 to 12] oxycodone pills).

Conclusion: Although the use of LBB in ISBs led to markedly lower VAS scores and less narcotic consumption on postoperative day (POD2), these findings can be regarded as not clinically notable. The difference was the equivalent of one oxycodone tablet, and VAS did not meet minimal clinically important difference. No other differences were found in MME consumed or VAS scores during the first 2 weeks postoperatively following RCR. Overall narcotic consumption was low in both groups.

Level of evidence: I.

背景:斜角间神经阻滞(ISB)常用于肩关节镜术后围手术期疼痛控制。布比卡因历来是isb使用的主要麻醉剂。2018年,美国食品和药物管理局批准了布比卡因脂质体用于isb。本研究旨在确定单独布比卡因(B)与脂质体布比卡因+布比卡因(LBB)对关节镜下肩袖修复(RCR)术后疼痛控制的影响。方法:2020年1月至2024年4月,遵循统一报告标准指南进行单中心、前瞻性、双盲、随机对照试验;128例首次接受关节镜RCR的阿片类药物患者按1:1随机分为b组(25毫升0.5%布比卡因)和LBB组(133毫克[10毫升]布比卡因脂体+ 15毫升0.5%布比卡因)。收集14天的人口统计、合并症、附加手术、每日吗啡毫克当量(MME)消耗和每日视觉模拟量表(VAS)疼痛评分。结果:年龄、性别、合并症或美国麻醉医师协会身体分类系统评分之间没有差异。术后第2天,LBB组MMEs消耗明显降低(0.0 [0.0 ~ 7.5]vs . 0.0 [0.0 ~ 15.0]; [P = 0.04]),术后第2天VAS评分显著改善(4.8±3.0 vs . 6.0±2.8;[P = 0.03])。其他每日MME消耗量、每日VAS评分或14天总MME均无显著差异。两组总MME消耗量中位数均较低(MME为35.6[7.5 ~ 88.1]或5[1 ~ 12]片羟考酮)。结论:虽然在ISBs中使用LBB可以显著降低VAS评分和减少术后一天的麻醉消耗(POD2),但这些发现在临床上并不显著。差异相当于一片羟考酮,VAS没有达到最小的临床重要差异。在RCR后的前2周内,MME消耗或VAS评分没有发现其他差异。两组的总体麻醉用量均较低。证据等级:1。
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引用次数: 0
A Preliminary, Three-Arm, Randomized, Double-Blinded, Placebo-Controlled Trial Comparing the Efficacy of Adductor Canal Pain Catheters Following Total Knee Arthroplasty. 一项初步、三臂、随机、双盲、安慰剂对照试验,比较全膝关节置换术后内收管疼痛导管的疗效。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-22 DOI: 10.5435/JAAOS-D-24-01351
Benjamin K Wilke, Courtney Sherman, Cameron K Ledford, Michael G Heckman, Launia J White, Bonnie Howe, Steven R Clendenen

Introduction: The United States has experienced a notable increase in opioid abuse over the past several years, with orthopaedic surgeons reported as the third-highest prescribers by specialty. Several studies have addressed opioid use after major orthopaedic procedures but largely focused on prescribing practices. There is limited data on the utility of adding adductor canal pain catheters to multimodal regimens following total knee arthroplasty for improved pain control and reduced opioid dependence. The purpose of this preliminary study was to compare single-shot adductor canal blocks to continuous infusion or intermittent bolus catheters, evaluating postoperative pain levels and duration of opioid use.

Methods: Sixty opioid-naive patients participated in a prospective, randomized, double-blinded, placebo-controlled trial. Following total knee arthroplasty, patients were randomized into one of three cohorts based on preoperative pain levels: (1) single-shot adductor canal block with placebo catheter, (2) continuous infusion catheter, or (3) intermittent bolus catheter. Postoperative protocols were similar except for the catheter. Patient outcomes were recorded for 60 days postoperatively.

Results: We found no difference in length of stay, oral morphine equivalents, use of on-demand medication, or pain scores (all P > 0.05) between the groups. Although the single-shot cohort trended toward a longer duration of opioid use (median 21 days) compared with the catheter groups (median 14 days for both), this did not approach statistical significance ( P = 0.59). We found no difference in Knee Injury and Osteoarthritis Outcome Score Jr scores between the groups at 30 or 60 days postoperatively (all P > 0.05).

Conclusion: In our preliminary study, we found no differences in clinical outcomes, pain scores, or patient-reported scores between a single-shot adductor canal block, a continuous infusion adductor canal catheter, and an intermittent bolus adductor catheter following total knee arthroplasty. Larger studies are needed to more definitively assess differences in outcomes between the treatment groups, particularly in the opioid-tolerant population.

导读:在过去几年中,美国的阿片类药物滥用显著增加,据报道,骨科医生是按专业划分的第三大处方者。几项研究已经解决了重大骨科手术后阿片类药物的使用问题,但主要集中在处方实践上。全膝关节置换术后,在多模式治疗方案中加入内收管疼痛导管以改善疼痛控制和减少阿片类药物依赖的数据有限。本初步研究的目的是比较单次内收肌管阻滞与连续输注或间歇大剂量导尿管,评估术后疼痛水平和阿片类药物使用的持续时间。方法:60名阿片类药物初始患者参加了一项前瞻性、随机、双盲、安慰剂对照试验。全膝关节置换术后,患者根据术前疼痛水平随机分为三个队列:(1)使用安慰剂导管进行单次内收管阻滞,(2)持续输注导管,或(3)间歇灌注导管。除导管外,术后方案相似。记录患者术后60天的预后。结果:我们发现两组患者的住院时间、口服吗啡当量、按需用药的使用或疼痛评分均无差异(P < 0.05)。虽然与导管组(两组均为中位14天)相比,单次注射组的阿片类药物使用时间更长(中位21天),但这没有接近统计学意义(P = 0.59)。术后30天和60天,两组患者膝关节损伤和骨关节炎预后评分Jr评分均无差异(P < 0.05)。结论:在我们的初步研究中,我们发现全膝关节置换术后单次内收管阻滞、连续内收管导管输注和间歇内收管导管输注在临床结果、疼痛评分或患者报告评分方面没有差异。需要更大规模的研究来更明确地评估治疗组之间的结果差异,特别是在阿片类药物耐受人群中。
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引用次数: 0
Assessing the Third Wave of Generative AI: Performance of Advanced Models on Text-based Questions From the 2024 Orthopaedic In-training Examination. 评估第三波生成人工智能:高级模型在2024年骨科培训考试文本问题上的表现
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-22 DOI: 10.5435/JAAOS-D-25-00441
Daniel S Hayes, Alyssa Barré, Ryan D Muchow

Introduction: Learners are rapidly using generative artificial intelligence (AI) models in their education. We assessed the performance of recently released or updated models on the 2024 American Academy of Orthopaedic Surgeons Orthopaedic In-training Examination for their potential applications in orthopaedic education.

Methods: Eleven models with recent enhancements in reasoning and research capabilities were evaluated. A total of 119 text-based questions were entered verbatim into each model. Model outputs were recorded as correct or incorrect. Additional analyses included reasoning time, citation accuracy, confidence in answer selection, and comparison with orthopaedic resident performance. References generated by the top performing model were compared with American Academy of Orthopaedic Surgeon Recommended Readings for incorrectly answered questions.

Results: Ten of 11 AI models exceeded the American Board of Orthopaedic Surgery minimal passing standard (67.7%). Eight models surpassed PGY5 resident performance. OpenAI's o1Pro with Deep Research achieved the highest accuracy (90.8%), outperforming the mean performance of PGY5 residents by 17.8%. More than half of the ResStudy Recommended Readings were cited as supporting references by the top performing model on questions it answered incorrectly. Subspecialty performance varied, with highest accuracy in Shoulder and Elbow and Sports Medicine questions. Longer reasoning times generally correlated with improved accuracy.

Discussion: Advanced AI models demonstrated substantial improvements over previous generations, with more than half of the tested models exceeding senior orthopaedic resident performance. Improved reasoning and research capabilities highlight the evolving capabilities of AI in medical education, although increased understanding of their utilization by learners is needed. Variability among subspecialties may suggest differences in training data or reasoning capabilities.

Conclusions: Modern AI models exhibit high proficiency on the Orthopaedic In-training Examination and may serve as valuable supplemental educational tools. Ongoing evaluation is warranted to understand their optimal integration into orthopaedic training while recognizing limitations in clinical reasoning, lived experience, and imaging interpretation.

学习者正在迅速地在他们的教育中使用生成式人工智能(AI)模型。我们评估了最近发布或更新的模型在2024年美国骨科医师学会骨科培训考试中的表现,以评估它们在骨科教育中的潜在应用。方法:对最近在推理和研究能力方面有所提高的11个模型进行评估。总共有119个基于文本的问题被逐字输入到每个模型中。模型输出记录为正确或不正确。其他分析包括推理时间,引用准确性,答案选择的信心,以及与骨科住院医师表现的比较。将表现最好的模型生成的参考文献与美国整形外科医师学会推荐的错误回答问题的参考文献进行比较。结果:11个人工智能模型中有10个超过了美国骨科手术委员会的最低合格标准(67.7%)。超过PGY5常驻性能的车型有8款。OpenAI的深度研究的o1Pro达到了最高的准确率(90.8%),比PGY5居民的平均表现高出17.8%。在回答错误的问题时,表现最好的模型引用了超过一半的ResStudy推荐读物作为支持参考。亚专业表现各不相同,在肩部和肘部和运动医学问题上准确率最高。较长的推理时间通常与提高的准确性相关。讨论:先进的人工智能模型比前几代有了实质性的改进,超过一半的测试模型超过了高级骨科住院医生的表现。推理和研究能力的提高凸显了人工智能在医学教育中的不断发展的能力,尽管学习者需要更多地了解它们的使用情况。亚专业之间的差异可能表明训练数据或推理能力的差异。结论:现代人工智能模型在骨科培训考试中表现出较高的熟练程度,可以作为有价值的补充教育工具。在认识到临床推理、生活经验和影像学解释的局限性的同时,有必要对其进行评估,以了解其与骨科训练的最佳结合。
{"title":"Assessing the Third Wave of Generative AI: Performance of Advanced Models on Text-based Questions From the 2024 Orthopaedic In-training Examination.","authors":"Daniel S Hayes, Alyssa Barré, Ryan D Muchow","doi":"10.5435/JAAOS-D-25-00441","DOIUrl":"10.5435/JAAOS-D-25-00441","url":null,"abstract":"<p><strong>Introduction: </strong>Learners are rapidly using generative artificial intelligence (AI) models in their education. We assessed the performance of recently released or updated models on the 2024 American Academy of Orthopaedic Surgeons Orthopaedic In-training Examination for their potential applications in orthopaedic education.</p><p><strong>Methods: </strong>Eleven models with recent enhancements in reasoning and research capabilities were evaluated. A total of 119 text-based questions were entered verbatim into each model. Model outputs were recorded as correct or incorrect. Additional analyses included reasoning time, citation accuracy, confidence in answer selection, and comparison with orthopaedic resident performance. References generated by the top performing model were compared with American Academy of Orthopaedic Surgeon Recommended Readings for incorrectly answered questions.</p><p><strong>Results: </strong>Ten of 11 AI models exceeded the American Board of Orthopaedic Surgery minimal passing standard (67.7%). Eight models surpassed PGY5 resident performance. OpenAI's o1Pro with Deep Research achieved the highest accuracy (90.8%), outperforming the mean performance of PGY5 residents by 17.8%. More than half of the ResStudy Recommended Readings were cited as supporting references by the top performing model on questions it answered incorrectly. Subspecialty performance varied, with highest accuracy in Shoulder and Elbow and Sports Medicine questions. Longer reasoning times generally correlated with improved accuracy.</p><p><strong>Discussion: </strong>Advanced AI models demonstrated substantial improvements over previous generations, with more than half of the tested models exceeding senior orthopaedic resident performance. Improved reasoning and research capabilities highlight the evolving capabilities of AI in medical education, although increased understanding of their utilization by learners is needed. Variability among subspecialties may suggest differences in training data or reasoning capabilities.</p><p><strong>Conclusions: </strong>Modern AI models exhibit high proficiency on the Orthopaedic In-training Examination and may serve as valuable supplemental educational tools. Ongoing evaluation is warranted to understand their optimal integration into orthopaedic training while recognizing limitations in clinical reasoning, lived experience, and imaging interpretation.</p>","PeriodicalId":51098,"journal":{"name":"Journal of the American Academy of Orthopaedic Surgeons","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145859042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of ACS NSQIP in Orthopaedic Surgery Practice, Research, and Quality Evaluation. ACS NSQIP在骨科外科实践、研究和质量评价中的作用。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-22 DOI: 10.5435/JAAOS-D-25-00842
Mikaela H Sullivan, Charles P Hannon, Alexander Y Shin, Nicholas Pulos

The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) is a multicenter variable-based data registry that facilitates surgical quality tracking, hospital benchmarking, and outcome predictions. ACS NSQIP data within Orthopaedic Surgery consist primarily of the 30 most common orthopaedic procedures and collect demographic and 30-day complication metrics for inpatient and outpatient procedures. Although the original intent of this large database was quality improvement, it has also been used extensively in orthopaedic research since 2010 to evaluate risk factors in orthopaedic surgery, despite systematic reviews demonstrating weaknesses in reproducibility and impact. Comparisons of ACS NSQIP to orthopaedic surgery-specific databases demonstrate a shortcoming of NSQIP in identifying patients, prevalence of complications, and tracking complications. Although ACS NSQIP provides a chance for large-scale data analysis in quality tracking and research, its reliability and usefulness in orthopaedic surgery remain to be established.

美国外科医师学会国家手术质量改进计划(ACS NSQIP)是一个多中心的基于变量的数据注册表,有助于手术质量跟踪、医院基准和结果预测。ACS NSQIP骨科外科数据主要包括30种最常见的骨科手术,并收集住院和门诊手术的人口统计学和30天并发症指标。尽管建立这个大型数据库的初衷是为了提高质量,但自2010年以来,它也被广泛用于骨科研究,以评估骨科手术的危险因素,尽管系统综述显示其可重复性和影响方面的弱点。ACS NSQIP与骨科手术数据库的比较表明,NSQIP在识别患者、并发症发生率和追踪并发症方面存在不足。尽管ACS NSQIP为质量跟踪和研究提供了大规模数据分析的机会,但其在骨科手术中的可靠性和实用性仍有待建立。
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引用次数: 0
The Impact of Preoperative Cannabis Use on Postoperative Pain and Opioid Use in Orthopaedic Surgery Patients: A Scoping Review. 术前大麻使用对骨科手术患者术后疼痛和阿片类药物使用的影响:一项范围审查。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-22 DOI: 10.5435/JAAOS-D-25-01030
Ahlam F Ashkar, Debra H Chan, Joseph Seta, Uma Srikumaran

Background: The use of cannabis for medical and recreational purposes has become increasingly prevalent. Emerging evidence suggests that postoperative cannabis-based medications influence postoperative opioid use for analgesia, although the impact of preoperative cannabis use on acute orthopaedic surgical outcomes remains unclear. The purpose of this study was to explore current literature regarding the associations of preoperative cannabis use with pain and opioid requirements after undergoing orthopaedic surgery.

Methods: A scoping review was conducted through a search of the PubMed, EMBASE, and Scopus databases. Two independent reviewers extracted information on population, measure of cannabis use, and postoperative outcomes, including Patient-Reported Outcomes Measurement Information System scores, pain, and morphine milligram equivalents.

Results: We identified 1,025 studies for potential inclusion. After screening all abstracts and titles, 19 orthopaedic studies were included, comprising 19,719 patients. Most were retrospective cohort studies, with 11 evaluating opioid use, three evaluating postoperative pain outcomes, and five evaluating both. Among the pain-related studies, three reported higher pain scores in their cannabis-user cohorts, one reported lower pain scores among cannabis users, and the remaining found no differences in pain. The studies evaluating opioid use found no notable difference in morphine milligram equivalent consumption between cannabis users and nonusers.

Discussion: Most evidence suggests that preoperative cannabis use has no effect on opioid use after orthopaedic surgery. Few articles investigated the associations of preoperative cannabis use with postoperative pain, and results were mixed, with only one study evaluating cannabis use in upper extremity surgical patients, suggesting the need for further exploration in some fields. No studies were able to measure duration of cannabis use, method of consumption, or potency because the use was either self-reported or based on a diagnosis of cannabis use disorder, indicating the need for future studies to stratify preoperative cannabis use by methods of ingestion and amount consumed.

背景:为医疗和娱乐目的使用大麻的情况日益普遍。新出现的证据表明,术后以大麻为基础的药物影响术后阿片类药物用于镇痛,尽管术前使用大麻对急性骨科手术结果的影响尚不清楚。本研究的目的是探讨骨科手术后术前使用大麻与疼痛和阿片类药物需求之间的关系。方法:通过检索PubMed、EMBASE和Scopus数据库进行范围综述。两名独立审稿人提取了有关人口、大麻使用措施和术后结果的信息,包括患者报告的结果测量信息系统评分、疼痛和吗啡毫克当量。结果:我们确定了1025项潜在纳入的研究。在筛选所有摘要和标题后,纳入19项骨科研究,包括19,719例患者。大多数是回顾性队列研究,其中11项评估阿片类药物的使用,3项评估术后疼痛结果,5项评估两者。在与疼痛相关的研究中,有三项报告大麻使用者的疼痛评分较高,一项报告大麻使用者的疼痛评分较低,其余的研究没有发现疼痛的差异。评估阿片类药物使用的研究发现,大麻使用者和非使用者之间吗啡毫克当量的消费量没有显着差异。讨论:大多数证据表明,术前使用大麻对骨科手术后阿片类药物的使用没有影响。很少有文章研究术前使用大麻与术后疼痛的关系,结果好坏参半,只有一项研究评估了上肢手术患者的大麻使用情况,这表明在某些领域需要进一步探索。没有研究能够测量大麻使用的持续时间、使用方法或效力,因为使用要么是自我报告的,要么是基于大麻使用障碍的诊断,这表明需要进行未来的研究,根据摄入方法和消费量对术前大麻使用进行分层。
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引用次数: 0
Changes in Clinical Practice After Publication of the Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) Randomized Controlled Trial. 肿瘤手术预防性抗生素方案(平价)随机对照试验发表后临床实践的变化。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-22 DOI: 10.5435/JAAOS-D-25-00374
Samir Sabharwal, Ricardo G Becker, Michael J Monument, Patricia Schneider, Thomas Schubert, Michelle Ghert, Carol D Morris

Background: The Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) trial was a multicenter randomized clinical trial comparing a 1-day with a 5-day postoperative intravenous antibiotic regimen after lower extremity bone tumor resection and endoprosthetic reconstruction. The trial found no difference in surgical site infections between groups, but a markedly increased risk for antibiotic-related complications in the 5-day group. The study was published in January 2022. The objective of this study was to assess the effect of these findings on the clinical practice of musculoskeletal oncologists.

Methods: We developed an anonymous survey exploring changes in clinical practice after the publication of the PARITY trial and electronically distributed the survey to practicing musculoskeletal oncologists through REDCap in March 2024. Data were analyzed descriptively, and changes in practice from before to after the publication of the PARITY study were analyzed through the Pearson chi-square test.

Results: We obtained 101 responses from surgeons across six continents. Nearly all respondents (94 of 101, 93%) were aware of the PARITY trial results. Forty respondents (40%) reported a meaningful change in clinical practice after PARITY, most frequently a reduction of antibiotic administration in >75% of patients. After PARITY, the proportion of respondents who reported limiting antibiotics to 24 hours increased from 25% to 51% ( P < 0.001), and the proportion prescribing oral antibiotics after discharge from the hospital declined from 23% to 16% ( P < 0.001). Among those who did not change their practice, personal experience/professional opinion was the most frequently cited reason. Adherence to institutional standards was cited as an additional barrier.

Conclusions: Many respondents reported meaningful change in their clinical practice after the publication of the PARITY trial, most notably limiting perioperative antibiotics to 24 hours. The complexities influencing the personal decision to adopt a notable change in clinical practice in response to new evidence warrant additional study.

Level of evidence: IV.

背景:肿瘤手术预防性抗生素方案(PARITY)试验是一项多中心随机临床试验,比较下肢骨肿瘤切除和假体内重建术后1天和5天静脉注射抗生素方案。试验发现两组手术部位感染没有差异,但5天组抗生素相关并发症的风险明显增加。这项研究发表于2022年1月。本研究的目的是评估这些发现对肌肉骨骼肿瘤学家临床实践的影响。方法:我们开展了一项匿名调查,探讨PARITY试验发表后临床实践的变化,并于2024年3月通过REDCap将调查以电子方式分发给实践肌肉骨骼肿瘤学家。对资料进行描述性分析,通过Pearson卡方检验分析PARITY研究发表前后的实践变化。结果:我们获得了来自六大洲外科医生的101份回复。几乎所有的受访者(101人中有94人,93%)都知道平价试验的结果。40个答复者(40%)报告了产检后临床实践有意义的变化,最常见的是减少了75%的患者的抗生素给药。在平价后,报告将抗生素限制在24小时的应答者比例从25%增加到51% (P < 0.001),出院后处方口服抗生素的比例从23%下降到16% (P < 0.001)。在那些没有改变他们的做法的人中,个人经验/专业意见是最常被引用的原因。遵守体制标准被认为是另一个障碍。结论:许多应答者报告在PARITY试验发表后,他们的临床实践发生了有意义的变化,最明显的是将围手术期抗生素限制在24小时内。影响个人决定在临床实践中采取显著改变以应对新证据的复杂性值得进一步研究。证据等级:四级。
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引用次数: 0
Understanding Acetabular Fractures: A Comprehensive Review. 理解髋臼骨折:一个全面的回顾。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-22 DOI: 10.5435/JAAOS-D-25-00741
Cyril Mauffrey, Nicholas Bellas, Guillaume David, Marie Le Baron

Acetabular fractures are complex injuries that demand a precise understanding of fracture morphology, radiographic interpretation, and surgical strategies. Although the Judet and Letournel classification system remains the benchmark, it poses notable challenges due to its complexity and learning curve. A narrative review was conducted synthesizing key concepts in classification, imaging interpretation, surgical planning, and fracture-specific considerations, with a focus on clinical utility. Established and novel classification systems were evaluated alongside reduction techniques and management pathways. The Judet and Letournel classification system remains clinically relevant, despite limitations in inter- and intraobserver reliability and transitional fracture classification. Surgeons benefit from reframing acetabular fractures into two major pattern families to streamline decision making. This paradigm improves recognition of displacement vectors, constant fragments, and optimal approaches. Ongoing refinement of educational tools and imaging strategies will support better outcomes. Surgical indications, including marginal impaction and geriatric management, are reviewed in detail. A simplified, concept-driven approach to acetabular fracture classification enhances clinical decision making and educational clarity. Integrating this approach with modern imaging and tailored fixation strategies offers a pathway toward improved outcomes in acetabular fracture care.

髋臼骨折是一种复杂的损伤,需要精确理解骨折形态、影像学解释和手术策略。尽管Judet和Letournel分类系统仍然是基准,但由于其复杂性和学习曲线,它提出了显着的挑战。本文对分类、影像学解释、手术计划和骨折特异性考虑等关键概念进行了综述,重点讨论了临床应用。已建立的和新的分类系统以及减少技术和管理途径进行了评估。Judet和Letournel分类系统仍然具有临床相关性,尽管在观察者之间和观察者内部的可靠性和过渡性骨折分类方面存在局限性。外科医生受益于将髋臼骨折重组为两个主要类型家族,以简化决策。这种模式改进了位移向量、常数片段和最优方法的识别。不断完善的教育工具和成像策略将支持更好的结果。手术指征,包括边缘嵌塞和老年管理,详细审查。一个简化的,概念驱动的方法来髋臼骨折分类提高临床决策和教育清晰度。将该方法与现代影像学和量身定制的固定策略相结合,为改善髋臼骨折的治疗效果提供了途径。
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引用次数: 0
The Current State of Orthopaedic Educational Leadership: A 5-Year Update. 骨科教育领导的现状:5年更新。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-19 DOI: 10.5435/JAAOS-D-25-01079
Andrew S Bi, Michelle A Richardson, Nina D Fisher, Eric J Strauss, Kenneth A Egol, Joseph D Zuckerman

Background: It is valuable to understand the changing landscape of leadership in orthopaedic surgery given its effect on medical school education, residency and fellowship training, and patient care. The purpose of this study was to provide a 5-year update on the current characteristics of orthopaedic educational leadership.

Methods: Based on the initial study, 159 accredited orthopaedic surgery residency programs were identified through cross-referencing the Accreditation Council for Graduate Medical Education (ACGME) website with the Electronic Residency Application Service Data, including training locations, academic rank, H-index, and publications for both program directors (PDs)and chairs, were obtained from public websites.

Results: One hundred fifty-nine PDs and 151 chairs were identified. Overall, 82 (51.6%) and 55 (36.4%) changes in PD and chairs, respectively, were observed. In addition, there were 18 (11.1%) female PDs in 2020 compared with 23 (14.5%) in 2025 (P = 0.379), and 3 (2.0%) female chairs in 2020 compared with 12 (7.9%) in 2025 (P = 0.016). Chairs were in practice for longer than PDs (26.8 versus 16.6 years [P < 0.001]) and in their position for longer (9.3 versus 7.8 years [P = 0.066]). Chairs were more likely to be professors (75.5% versus 22.6% [P < 0.001]), have higher H-index (30.4 versus 14.2 [P < 0.001]), and have more publications (95.9 versus 35.4 [P < 0.001]). PDs were more likely to have completed residency at their current institution. The most common subspecialties were trauma for PDs and sports for Chairs.

Conclusion: There have been notable changes in orthopaedic surgery leadership positions within the past 5 years, with a significant increase in female Chairs. Those who are interested in pursuing leadership positions or in the changing landscape of orthopaedic leadership may benefit from the findings of this study.

背景:鉴于其对医学院教育、住院医师和研究员培训以及患者护理的影响,了解骨科外科领导层的变化是有价值的。本研究的目的是提供5年来骨科教育领导的最新特征。方法:在初步研究的基础上,通过交叉参考研究生医学教育认证委员会(ACGME)网站和电子住院医师申请服务数据(包括培训地点、学术排名、h指数和项目主任(pd)和主席的出版物),确定了159个经认证的骨科住院医师项目。结果:共鉴定出pd 159个,椅子151个。总的来说,PD和椅子分别发生了82例(51.6%)和55例(36.4%)的变化。此外,2020年女性董事总经理为18人(11.1%),2025年为23人(14.5%)(P = 0.379); 2020年女性董事长为3人(2.0%),2025年为12人(7.9%)(P = 0.016)。主席的工作时间比博士长(26.8年对16.6年[P < 0.001]),在他们的位置上的时间也更长(9.3年对7.8年[P = 0.066])。主席更有可能成为教授(75.5%比22.6% [P < 0.001]), h指数更高(30.4比14.2 [P < 0.001]),发表文章更多(95.9比35.4 [P < 0.001])。pd更有可能在他们目前的机构完成住院治疗。最常见的亚专科是pd的创伤和椅子的运动。结论:近5年来骨科领导职位发生了明显变化,女性主席明显增加。那些有兴趣追求领导职位或对骨科领导的变化感兴趣的人可能会从这项研究的发现中受益。
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引用次数: 0
Diagnosis and Management of Degenerative Cervical Myelopathy. 退行性颈椎病的诊断和治疗。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-15 Epub Date: 2025-06-24 DOI: 10.5435/JAAOS-D-25-00026
Charles-Antoine Mechas, Mohamed Sarraj, Melvin Helgeson

The treatment of degenerative cervical myelopathy (DCM), which encompasses cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament, has progressed markedly over the past few decades. The natural history of DCM includes multiple phenotypes: a slow deterioration, a stepwise pattern of decline, and rapidly progressive functional decline. Symptoms include gait disturbance, decreased fine motor abilities, weakness, sensory changes, and neck pain. Classically, those with minimal or early symptoms were treated conservatively with observation; however, newer investigations suggest evidence for early surgical treatment. Those with objective myelopathic symptoms confirmed by imaging demonstrating spinal cord compression are indicated for surgery. Surgical treatment can be accomplished with multiple different technical approaches including anteriorly based surgery, posteriorly based surgery, and combined techniques. Traditionally, anterior surgery included anterior cervical diskectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF), but increasing investigations incorporate cervical disk arthroplasty in this cohort of patients. Historically, laminectomy for posterior decompression was a hallmark of treatment in DCM; however, this led to complications such as postlaminectomy kyphosis and instability which has led to substitution of this treatment by laminoplasty and laminectomy + fusion. Surgical adjuncts such as Riluzole have demonstrated promise in the treatment of DCM patients. Success in surgical treatment is defined by decompression of the spinal cord to halt progression of symptoms and in some patients improve function. Although surgical treatment has yielded success in the treatment of DCM, perioperative complications can be devastating which make surgical technique and patient selection paramount.

治疗退行性脊髓型颈椎病(DCM),包括脊髓型颈椎病和后纵韧带骨化,在过去的几十年里取得了显著的进展。DCM的自然历史包括多种表型:缓慢恶化,逐步下降模式和快速进行性功能下降。症状包括步态障碍、精细运动能力下降、虚弱、感觉改变和颈部疼痛。典型的做法是,症状轻微或早期的患者采用保守的观察治疗;然而,较新的调查显示早期手术治疗的证据。客观脊髓病症状经影像学证实为脊髓受压者,适用手术治疗。手术治疗可以通过多种不同的技术方法来完成,包括前路手术、后路手术和联合技术。传统上,前路手术包括前颈椎间盘切除术和融合术(ACDF)和前颈椎体切除术和融合术(ACCF),但越来越多的研究在这组患者中纳入了颈椎椎间盘置换术。从历史上看,椎板切除术后路减压是治疗DCM的标志;然而,这导致并发症,如椎板切除术后的后凸和不稳定,导致用椎板成形术和椎板切除术+融合来替代这种治疗。利鲁唑等手术辅助药物在治疗DCM患者方面已显示出前景。手术治疗成功的定义是对脊髓进行减压,以阻止症状的进展,并在一些患者中改善功能。虽然手术治疗在DCM的治疗中取得了成功,但围手术期并发症可能是毁灭性的,这使得手术技术和患者的选择至关重要。
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引用次数: 0
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Journal of the American Academy of Orthopaedic Surgeons
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