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A Machine Learning Approach to Predicting Radiographic Outcomes of Nonsurgically Treated Distal Radius Fractures. 机器学习方法预测非手术治疗桡骨远端骨折的影像学结果。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-05 DOI: 10.5435/JAAOS-D-25-01150
Eric R Taleghani, Ruihong Lyu, Taylor Shackleford, James Rex, Isaac Hale, Thomas M Talavage, Matthew M Florczynski

Introduction: Several statistical models have been developed to predict the stability of distal radius fractures after closed reduction, but their findings have not been consistently reproduced. We aimed to develop a machine learning (ML) model to predict radiographic outcomes of nonsurgically treated distal radius fractures based on pre-reduction and postreduction radiographic parameters and demographic variables.

Methods: Adults with displaced distal radius fractures at a single institution between 2012 and 2024 were identified through retrospective chart review. Inclusion criteria required closed reduction in the emergency department, with radiographs obtained before reduction, immediately after reduction, and 6 weeks after reduction. At 6 weeks, treatment outcomes were classified as "success" or "failure" based on American Academy of Orthopaedic Surgeons acceptable reduction parameters. Five ML models were trained to predict 6-week outcomes using demographic data and pre-reduction and postreduction radiographic measurements. The 10 parameters with highest Shapley values for predictive ability were used to create an interpretable composite model.

Results: Among 1,227 patients, 152 met the inclusion criteria (mean age: 61.4 ± 20.2 years; 75.7% female). The composite model correctly predicted outcomes in 25 of 31 patients, achieving an accuracy, precision, and recall of 81%; area under the curve of 0.84; and F1 score of 0.81. Restoration of postreduction palmar tilt, radial height, and excellent reduction based on the Lindstrom score were most predictive of 6-week radiographic outcomes. The best performing decision tree showed the following cutoffs predictive of treatment failure: +4.7 mm of pre-reduction ulnar variance, 8° of postreduction dorsal tilt, and <18.8° of postreduction radial inclination.

Conclusion: This study developed an ML model that accurately predicts 6-week radiographic outcomes in nonsurgically treated distal radius fractures. Postreduction parameters were the strongest predictors, underscoring the importance of a high-quality closed reduction. This study validates the potential of ML as a predictive tool in this setting.

已经建立了几个统计模型来预测桡骨远端骨折闭合复位后的稳定性,但他们的发现并没有一致的再现。我们的目标是开发一个机器学习(ML)模型,根据复位前和复位后的放射学参数和人口统计学变量来预测非手术治疗桡骨远端骨折的放射学结果。方法:2012年至2024年间,通过回顾性病历回顾,对同一医院的成人桡骨远端移位骨折患者进行分析。纳入标准要求在急诊科进行闭合复位,并在复位前、复位后立即和复位后6周拍摄x线片。6周时,根据美国骨科医师学会可接受复位参数将治疗结果分为“成功”或“失败”。训练5个ML模型,利用人口统计学数据和复位前和复位后的x线测量来预测6周的结果。预测能力Shapley值最高的10个参数被用来创建可解释的复合模型。结果:1227例患者中,152例符合纳入标准(平均年龄:61.4±20.2岁,女性占75.7%)。复合模型正确预测了31例患者中25例的预后,准确度、精密度和召回率达到81%;曲线下面积0.84;F1得分为0.81。复位后掌倾斜、桡骨高度的恢复以及基于Lindstrom评分的良好复位是预测6周放射学结果的最佳指标。表现最好的决策树显示了以下预测治疗失败的截止点:复位前尺骨方差+4.7 mm,复位后背倾角8°。结论:本研究建立了一个ML模型,可以准确预测非手术治疗桡骨远端骨折6周的影像学结果。术后参数是最强的预测因子,强调了高质量闭合复位的重要性。这项研究验证了机器学习在这种情况下作为预测工具的潜力。
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引用次数: 0
Two-Incision Anterior Cruciate Ligament Reconstruction. 双切口前交叉韧带重建。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-05 DOI: 10.5435/JAAOS-D-25-00137
David L Bernholt, Kurt P Spindler, Fred M Azar, Rick W Wright

Two-incision anterior cruciate ligament reconstruction (ACLR) is a well-established technique used to perform an arthroscopically assisted ACLR. Historically, this approach to ACLR was once considered the benchmark; however, with evolving arthroscopic technology and the rise of more minimally invasive techniques, this approach to ACLR has become less popular. The two-incision technique still has notable clinical utility because it can (1) increase the surgeon's ability to perform a single-stage revision ACLR and (2) help avoid graft-tunnel mismatch in primary ACLR with a patellar tendon autograft when encountering a long tendon. This technique, when coupled with metal screws and an autograft tendon, is also the lowest cost ACLR technique that allows independent femoral tunnel positioning and thus should be considered as an option for primary ACLR by surgeons prioritizing cost containment without compromising surgical outcomes.

双切口前交叉韧带重建(ACLR)是一种成熟的技术,用于进行关节镜辅助的ACLR。从历史上看,这种ACLR方法曾经被认为是基准;然而,随着关节镜技术的发展和微创技术的兴起,这种方法已经不那么流行了。双切口技术仍然具有显著的临床应用价值,因为它可以(1)提高外科医生进行单期ACLR翻修的能力,(2)在原发性ACLR与自体髌骨肌腱移植遇到长肌腱时,有助于避免移植物-隧道不匹配。当该技术与金属螺钉和自体肌腱联合使用时,也是成本最低的ACLR技术,允许独立的股骨隧道定位,因此外科医生应优先考虑在不影响手术结果的情况下控制成本作为原发性ACLR的选择。
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引用次数: 0
Reply to Letter to the Editor: Use of Oral Antibiotics in the Treatment of Spinal Infections. 给编辑的回信:使用口服抗生素治疗脊柱感染。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-02 DOI: 10.5435/JAAOS-D-25-00857
Saurabh Rawall, Luke A Hiatt, Sakthivel M Rajaram, Steven Theiss
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引用次数: 0
Carpometacarpal Joint Dislocations and Fracture Dislocations of the Index Through Small Digits. 手掌骨关节脱位及指关节骨折脱位。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-01 Epub Date: 2025-10-03 DOI: 10.5435/JAAOS-D-25-00583
Gregory G Gallant, Michael Rivlin, Richard J Tosti, Pedro K Beredjiklian

Index through small carpometacarpal joint dislocations and fracture dislocations are injuries that require early recognition to prevent future pain and dysfunction. This review article discusses the anatomy, mechanism of injury, classification, clinical examination, radiographic evaluation, and treatment options for these particular injuries. The goal of this review article is to provide the best treatment options for general orthopaedic surgeons and hand surgeons in the care of these injuries. The authors preferred method of treatment is also discussed.

食指到小腕关节脱位和骨折脱位是需要早期识别的损伤,以防止未来的疼痛和功能障碍。这篇综述文章讨论了这些特殊损伤的解剖、损伤机制、分类、临床检查、影像学评估和治疗选择。这篇综述文章的目的是为普通骨科医生和手外科医生提供治疗这些损伤的最佳选择。并讨论了作者的首选处理方法。
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引用次数: 0
Expanding Indications for Temporary Dorsal Wrist Spanning Plate Fixation. 扩展临时腕背跨越钢板固定的适应症。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-01 Epub Date: 2025-09-09 DOI: 10.5435/JAAOS-D-25-00577
Abdo Bachoura, David Hirsch, Amir Kachooei, Pedro Beredjiklian

Dorsal wrist spanning plating has proven to be an effective, reliable, and versatile tool in the treatment of distal radius fractures and numerous other carpal conditions. Despite its shortcomings including a necessary second procedure for implant removal, this technique remains a very useful option in the upper extremity surgeon's toolbox. This article reviews the historical development, expanding indications, and technical details of temporary wrist spanning plate fixation.

背侧腕跨钢板已被证明是治疗桡骨远端骨折和许多其他腕关节疾病的有效、可靠和通用的工具。尽管它的缺点包括必须进行第二次手术来移除植入物,但这项技术仍然是上肢外科医生工具箱中非常有用的选择。本文回顾了腕部临时跨越钢板固定的历史发展、扩展适应症和技术细节。
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引用次数: 0
Formal Hand Therapy for Patients Following Basal Joint Arthroplasty: Potential Benefits Versus Added Costs. 基底关节置换术后患者的正式手部治疗:潜在的益处与增加的成本。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-01 Epub Date: 2025-09-10 DOI: 10.5435/JAAOS-D-25-00395
John R Baumann, Bryce F Rizvanovic, Julia A V Nuelle, Daniel A London

Background: There is no consensus on whether the benefits of participating in formal hand therapy outweigh the investment required for patients following basal joint arthroplasty. The purpose of this study was to compare patient-reported and functional outcome measures between patients who did and did not participate in formal hand therapy following basal joint arthroplasty. Furthermore, we evaluated the distance patients traveled and the financial burden associated with participating in formal hand therapy.

Methods: Using a retrospective cohort study design, patients who underwent primary basal joint arthroplasty by the fellowship-trained orthopaedic hand surgeons at our institution between 2021 and 2023 were included in this study. Patients who did not have complete data or had revision surgery were excluded. Patient-Reported Outcomes Measurement Information System Upper Extremity (PROMIS UE) scores, Kapandji scores, therapy data, and therapy costs were collected. Mann-Whitney U -tests, chi square tests, and Z-tests were used for statistical analysis. The cutoff for statistical significance was set at P < 0.05.

Results: A total of 73 surgeries in 70 patients were included in this study; 33 out of 73 surgical encounters participated in formal therapy after surgery. The median max Kapandji score and mean increase in PROMIS UE score were higher in the therapy users compared with nontherapy users. Although these differences in PROMIS UE scores were not statistically significant, they were greater than the proposed minimal clinically important difference. Formal hand therapy users did attend more postoperative clinic appointments than nontherapy users. Both the patient-reported and standardized estimated cost of therapy and postoperative clinic appointment cost were higher for therapy groups compared with nontherapy groups.

Conclusion: The results of this study suggest that although there is no statistically significant difference in PROMIS UE improvement between groups, formal hand therapy may provide a clinically meaningful benefit.

背景:对于参加正式手部治疗的益处是否超过基底关节置换术患者所需的投资尚无共识。本研究的目的是比较基底关节置换术后接受和未接受正式手部治疗的患者的报告和功能结果。此外,我们评估了与参加正式手部治疗相关的路程和经济负担。方法:采用回顾性队列研究设计,将2021年至2023年间在我院接受过奖学金培训的骨科手外科医生进行原发性基底关节置换术的患者纳入本研究。没有完整资料或做过翻修手术的患者被排除在外。收集患者报告的结果测量信息系统(PROMIS UE)评分、Kapandji评分、治疗数据和治疗费用。采用Mann-Whitney u检验、卡方检验和z检验进行统计分析。差异有统计学意义的临界值为P < 0.05。结果:本研究共纳入70例患者的73例手术;73例手术患者中有33例术后接受了正式治疗。与未接受治疗的患者相比,接受治疗的患者Kapandji评分的中位最大值和PROMIS UE评分的平均增加更高。尽管PROMIS UE评分的这些差异没有统计学意义,但它们大于建议的最小临床重要差异。正式的手部治疗使用者确实比非治疗使用者参加了更多的术后诊所预约。治疗组患者报告的和标准化的估计治疗费用和术后门诊预约费用均高于非治疗组。结论:本研究结果表明,尽管两组间PROMIS UE改善无统计学差异,但正式的手部治疗可能提供有临床意义的益处。
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引用次数: 0
The Effect of Serum Vitamin D Level on Wound Healing Process After Open Carpal Tunnel Release Surgery: Clinical Outcomes of 55 Cases. 55例开放腕管松解术后血清维生素D水平对创面愈合的影响
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-01 Epub Date: 2025-07-18 DOI: 10.5435/JAAOS-D-25-00410
Mustafa Özyıldıran, Mustafa Onur Karaca

Background: There are many systemic or local factors that can disrupt wound healing process. The aim of the study is to evaluate the effect of serum vitamin D levels on the wound healing process after open carpal tunnel release surgery.

Methods: This study is a single-center retrospective analysis of patients treated between December 2022 and June 2024. Patients who underwent OCTR surgery under wide-awake local anesthesia with no tourniquet were included. Patients with comorbidities and risk factors known to negatively affect the wound healing process were excluded. Preoperative 25-hydroxyvitamin D levels were recorded. On the 14th postoperative day, patients were evaluated for wound healing status and categorized into two groups: "delayed wound healing" and "normal wound healing."

Results: Forty-six women (83.6%) and nine men (16.4%) with a mean age of 51.7 years were included. Normal wound healing was observed in 34 patients (61.8%), whereas delayed wound healing was observed in 21 patients (38.2%). The mean 25-hydroxyvitamin D level was 19.66 ng/mL in the normal wound healing group, whereas it was 11.05 ng/mL in the delayed wound healing group ( P = 0.001). Of the 12 patients with a 25(OH)D level ≥20 ng/mL, only one patient (8.3%) experienced delayed wound healing, whereas among the 43 patients with a level <20 ng/mL, 20 (46.5%) had delayed wound healing ( P = 0.02). The Boston Carpal Tunnel Questionnaire total scores at the postoperative 1st month were found to be superior in the normal wound healing group compared with the delayed wound healing group (2.04 ± 0.34 vs. 2.23 ± 0.33, respectively, P = 0.04). However, no significant difference was found in clinical scores at the 3rd postoperative month (1.62 ± 0.31 vs. 1.69 ± 0.35, P = 0.30).

Conclusion: There is an association between vitamin D deficiency and delayed wound healing after OCTR surgery.

背景:有许多全身或局部因素可破坏伤口愈合过程。本研究的目的是评估血清维生素D水平对开放腕管松解手术后伤口愈合过程的影响。方法:本研究采用单中心回顾性分析,纳入2022年12月至2024年6月期间接受治疗的患者。在无止血带的全清醒局麻下行OCTR手术的患者也包括在内。排除了已知对伤口愈合过程有负面影响的合并症和危险因素的患者。术前记录25-羟基维生素D水平。术后第14天评估患者创面愈合情况,并将患者分为“延迟创面愈合”和“正常创面愈合”两组。结果:女性46例(83.6%),男性9例(16.4%),平均年龄51.7岁。34例(61.8%)患者创面正常愈合,21例(38.2%)患者创面延迟愈合。伤口正常愈合组25-羟基维生素D平均水平为19.66 ng/mL,伤口延迟愈合组25-羟基维生素D平均水平为11.05 ng/mL (P = 0.001)。在25(OH)D水平≥20 ng/mL的12例患者中,只有1例患者(8.3%)出现伤口延迟愈合,而在43例患者中,维生素D缺乏与OCTR术后伤口延迟愈合之间存在关联。
{"title":"The Effect of Serum Vitamin D Level on Wound Healing Process After Open Carpal Tunnel Release Surgery: Clinical Outcomes of 55 Cases.","authors":"Mustafa Özyıldıran, Mustafa Onur Karaca","doi":"10.5435/JAAOS-D-25-00410","DOIUrl":"10.5435/JAAOS-D-25-00410","url":null,"abstract":"<p><strong>Background: </strong>There are many systemic or local factors that can disrupt wound healing process. The aim of the study is to evaluate the effect of serum vitamin D levels on the wound healing process after open carpal tunnel release surgery.</p><p><strong>Methods: </strong>This study is a single-center retrospective analysis of patients treated between December 2022 and June 2024. Patients who underwent OCTR surgery under wide-awake local anesthesia with no tourniquet were included. Patients with comorbidities and risk factors known to negatively affect the wound healing process were excluded. Preoperative 25-hydroxyvitamin D levels were recorded. On the 14th postoperative day, patients were evaluated for wound healing status and categorized into two groups: \"delayed wound healing\" and \"normal wound healing.\"</p><p><strong>Results: </strong>Forty-six women (83.6%) and nine men (16.4%) with a mean age of 51.7 years were included. Normal wound healing was observed in 34 patients (61.8%), whereas delayed wound healing was observed in 21 patients (38.2%). The mean 25-hydroxyvitamin D level was 19.66 ng/mL in the normal wound healing group, whereas it was 11.05 ng/mL in the delayed wound healing group ( P = 0.001). Of the 12 patients with a 25(OH)D level ≥20 ng/mL, only one patient (8.3%) experienced delayed wound healing, whereas among the 43 patients with a level <20 ng/mL, 20 (46.5%) had delayed wound healing ( P = 0.02). The Boston Carpal Tunnel Questionnaire total scores at the postoperative 1st month were found to be superior in the normal wound healing group compared with the delayed wound healing group (2.04 ± 0.34 vs. 2.23 ± 0.33, respectively, P = 0.04). However, no significant difference was found in clinical scores at the 3rd postoperative month (1.62 ± 0.31 vs. 1.69 ± 0.35, P = 0.30).</p><p><strong>Conclusion: </strong>There is an association between vitamin D deficiency and delayed wound healing after OCTR surgery.</p>","PeriodicalId":51098,"journal":{"name":"Journal of the American Academy of Orthopaedic Surgeons","volume":" ","pages":"e60-e68"},"PeriodicalIF":2.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Techniques to Manage the Unstable Volar Lunate Facet Fragment of Distal Radius Fractures. 桡骨远端骨折掌侧月骨小面碎片不稳定的外科治疗技术。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-01 Epub Date: 2025-09-11 DOI: 10.5435/JAAOS-D-25-00035
Shrina Parikh, Srivathsan Ramesh, Arpam Dutta, Matthew Koepplinger

Introduction: The surgical treatment of distal radius fractures is one of the most common procedures performed by orthopaedic surgeons. Intraarticular fracture patterns, specifically those involving the volar lunate facet, can be particularly problematic because this fragment is crucial to radiocarpal and distal radioulnar joint (DRUJ) stability. The problems associated with these patterns are attributed to the anatomy of the volar ulnar corner of the distal radius as well as the limitations of conventional volar distal radius implants and common surgical exposures.

Methods: This article will review the distal radius anatomy specific to the volar ulnar corner; a review of conventional distal radius volar plating technique; indications and associated complications of instability of the volar lunate facet; and techniques for volar lunate facet fixation.

Results: Fractures of the volar lunate facet are typically associated with fracture patterns involving the entire distal radius articular block with varying degrees of comminution, but it is not uncommon to encounter these fractures in isolation as well. There are many techniques and constructs available to treat these fractures, all of which involve careful preoperative planning and precise execution.

Discussion: The appropriate placement of volar distal radius plates is critical, and when performed, can address most intraarticular distal radius fractures that do not include the subset of fractures with smaller volar lunate facet fragments. Adequate intraoperative fluoroscopy with visualization of the incisura of the DRUJ should furthermore be achieved to avoid intraarticular penetration of the DRUJ. At the conclusion of fixation, lateral and inclined lateral fluoroscopic imaging should be obtained to confirm extraarticular screw placement proximal to the lunate and scaphoid facets, respectively. Consideration of an intraoperative assessment is warranted given the potential instability of these fractures.

手术治疗桡骨远端骨折是骨科医生最常用的治疗方法之一。关节内骨折类型,特别是那些涉及掌侧月骨突的骨折,可能特别成问题,因为该碎片对桡腕关节和远端桡尺关节(DRUJ)的稳定性至关重要。与这些模式相关的问题归因于桡骨远端掌侧尺角的解剖结构,以及传统的桡骨远端掌侧植入物和常见手术暴露的局限性。方法:本文将回顾桡骨远端掌尺角的解剖;常规桡骨远端掌侧钢板技术综述掌侧月骨突不稳定的适应症和相关并发症;掌侧月骨小关节固定技术。结果:掌侧月骨小面骨折通常与涉及整个远端桡骨关节块的骨折类型相关,并伴有不同程度的粉碎性骨折,但孤立地遇到这些骨折也并不罕见。有许多技术和结构可用于治疗这些骨折,所有这些都需要仔细的术前计划和精确的执行。讨论:桡骨掌侧远端钢板的适当放置是至关重要的,当实施时,可以治疗大多数不包括掌侧月骨小面碎片骨折的桡骨远端关节内骨折。术中应进一步进行充分的透视,显示下颌骨切牙,以避免下颌骨关节内穿透。固定结束后,应进行侧位和斜位透视成像,以确定关节外螺钉分别放置在月骨和舟状骨近端。考虑到这些骨折潜在的不稳定性,术中评估是有必要的。
{"title":"Surgical Techniques to Manage the Unstable Volar Lunate Facet Fragment of Distal Radius Fractures.","authors":"Shrina Parikh, Srivathsan Ramesh, Arpam Dutta, Matthew Koepplinger","doi":"10.5435/JAAOS-D-25-00035","DOIUrl":"10.5435/JAAOS-D-25-00035","url":null,"abstract":"<p><strong>Introduction: </strong>The surgical treatment of distal radius fractures is one of the most common procedures performed by orthopaedic surgeons. Intraarticular fracture patterns, specifically those involving the volar lunate facet, can be particularly problematic because this fragment is crucial to radiocarpal and distal radioulnar joint (DRUJ) stability. The problems associated with these patterns are attributed to the anatomy of the volar ulnar corner of the distal radius as well as the limitations of conventional volar distal radius implants and common surgical exposures.</p><p><strong>Methods: </strong>This article will review the distal radius anatomy specific to the volar ulnar corner; a review of conventional distal radius volar plating technique; indications and associated complications of instability of the volar lunate facet; and techniques for volar lunate facet fixation.</p><p><strong>Results: </strong>Fractures of the volar lunate facet are typically associated with fracture patterns involving the entire distal radius articular block with varying degrees of comminution, but it is not uncommon to encounter these fractures in isolation as well. There are many techniques and constructs available to treat these fractures, all of which involve careful preoperative planning and precise execution.</p><p><strong>Discussion: </strong>The appropriate placement of volar distal radius plates is critical, and when performed, can address most intraarticular distal radius fractures that do not include the subset of fractures with smaller volar lunate facet fragments. Adequate intraoperative fluoroscopy with visualization of the incisura of the DRUJ should furthermore be achieved to avoid intraarticular penetration of the DRUJ. At the conclusion of fixation, lateral and inclined lateral fluoroscopic imaging should be obtained to confirm extraarticular screw placement proximal to the lunate and scaphoid facets, respectively. Consideration of an intraoperative assessment is warranted given the potential instability of these fractures.</p>","PeriodicalId":51098,"journal":{"name":"Journal of the American Academy of Orthopaedic Surgeons","volume":" ","pages":"e124-e132"},"PeriodicalIF":2.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship Between Conflict of Interest and Reported Outcomes After Upper Extremity Nerve Reconstruction Using Acellular Nerve Allografts: A Systematic Review. 利益冲突与使用脱细胞异体神经移植重建上肢神经的报道结果之间的关系:一项系统综述。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-01 Epub Date: 2025-09-25 DOI: 10.5435/JAAOS-D-25-00622
Daniel Bahat, Sean Frisbie, Samantha Maasarani, Christopher Jou, Kyle Chepla

Introduction: Acellular nerve allografts (ANAs) are increasingly used for peripheral nerve repair. However, the effect of industry sponsorship on reported outcomes remains unclear. This review evaluates functional outcomes following upper extremity nerve reconstruction with ANAs, stratified by conflict of interest (COI).

Methods: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses-guided search of MEDLINE, PubMed, and Embase identified clinical studies using ANAs. Data extracted included study design, patient age, nerve gap length, outcome measures (Medical Research Council Classification, Disabilities of the Arm, Shoulder, and Hand, visual analog scale), and COI status. Outcomes were compared using independent t -tests.

Results: Twenty-eight studies met inclusion criteria. Non-COI studies involved older patients and longer nerve gaps. Motor recovery was markedly higher in COI studies compared with non-COI studies (69.8% vs. 14.1%; P < 0.001), whereas sensory recovery also differed markedly (25.9% vs. 80.4%; P < 0.001).

Discussion: These findings suggest that outcome reporting may be influenced by funding source. The use of subjective measures and study design limitations further complicate objective interpretation.

Conclusion: Although ANAs offer promise, current evidence is shaped by sponsorship bias. Future research should prioritize standardized, objective assessments, and independent, prospective studies to guide clinical decision making.

摘要:脱细胞神经异体移植(ANAs)越来越多地用于周围神经修复。然而,行业赞助对报告结果的影响仍不清楚。本综述评估了使用ANAs进行上肢神经重建后的功能结果,并按利益冲突(COI)分层。方法:在MEDLINE、PubMed和Embase的系统评价和meta分析指导下,优选使用ANAs进行临床研究的报告项目。提取的数据包括研究设计、患者年龄、神经间隙长度、结果测量(医学研究委员会分类、手臂、肩部和手部残疾、视觉模拟量表)和COI状态。结果采用独立t检验进行比较。结果:28项研究符合纳入标准。非coi研究涉及老年患者和较长的神经间隙。与非COI研究相比,COI研究中的运动恢复明显更高(69.8% vs. 14.1%, P < 0.001),而感觉恢复也显著不同(25.9% vs. 80.4%, P < 0.001)。讨论:这些发现表明结果报告可能受到资金来源的影响。主观测量的使用和研究设计的限制进一步使客观解释复杂化。结论:尽管ANAs提供了希望,但目前的证据受到赞助偏见的影响。未来的研究应优先考虑标准化、客观的评估和独立的前瞻性研究,以指导临床决策。
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引用次数: 0
The Effect of Bridge Plate Duration on Range of Motion: A Breakpoint Modelling Approach for Distal Radius Fractures Treated With Dorsal Wrist Spanning Bridge Plate. 桥钢板持续时间对活动范围的影响:腕背跨桥钢板治疗桡骨远端骨折的断点建模方法。
IF 2.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-01 Epub Date: 2025-07-03 DOI: 10.5435/JAAOS-D-24-00604
Jessica M Welch, Bradley J Lauck, Tyler S Pidgeon, Marc J Richard, Christopher S Klifto, Daniel J Lorenzana, David S Ruch

Background: Dorsal wrist spanning plate (DWSP) fixation is a technique used to treat distal radius fractures with severe metaphyseal comminution, diaphyseal extension, and other complex fracture patterns. One concern of this technique is the potential risk of stiffness due to prolonged immobilization. The purpose of our study was to examine the association of DWSP duration on range of motion (ROM) outcomes after plate removal.

Methods: Patients who underwent DWSP fixation for distal radius fracture with greater than 6 months of follow-up after DWSP removal at a single institution were retrospectively identified. Patients with a concomitant upper extremity injury were excluded. The primary outcome of interest was ROM. Secondary outcomes included visual analog scale pain scores and radiographic measurements. A piecewise regression analysis was run to evaluate for a nonlinear relationship between DWSP duration and ROM.

Results: Fifty-one patients were included for analysis. DWSP removal occurred at a mean of 110 days (range, 59-182 days). Median duration of follow-up after DWSP removal was 11.7 months (interquartile range = 8.2 months to 1.8 years). No significant association was observed between DWSP duration and visual analog scale ( P = 0.11), complication rate ( P = 0.45), radial inclination ( P = 0.57), radial height ( P = 0.74), or volar tilt ( P = 0.13). Piecewise regression demonstrated a statistically significant reduction in supination ( P = 0.001), pronation ( P = < 0.001), and wrist flexion ( P = 0.014) for DWSP >120 days when controlling for age, sex, polytrauma, duration of follow-up, and additional fixation.

Discussion: There is a nonlinear association between DWSP duration and wrist ROM (flexion, supination, and pronation). When DWSP duration is longer than 120 days, there is a negative correlation with ROM when controlling for covariates. When DWSP duration is less than or equal to 120 days, there is no correlation with ROM. Our findings suggest that patients with longer duration of DWSP duration (>120 days) are more likely to have range-of-motion limitations; additional research is necessary to determine whether implant retention longer than 120 days by itself or fracture or patient-specific factors which require longer implant retention are the causative agents for this motion limitation.

Level of evidence: Retrospective cohort, Level IV.

背景:背侧腕跨钢板(DWSP)固定是一种用于治疗伴有严重干骺端粉碎、干骺端延伸和其他复杂骨折类型的桡骨远端骨折的技术。该技术的一个问题是由于长时间固定造成的僵硬的潜在风险。我们研究的目的是检查DWSP持续时间与钢板取出后活动范围(ROM)结果的关系。方法:回顾性分析在同一家医院接受DWSP固定治疗桡骨远端骨折的患者,在DWSP取出后随访时间超过6个月。排除伴有上肢损伤的患者。主要结局是ROM。次要结局包括视觉模拟量表疼痛评分和x线测量。采用分段回归分析来评估DWSP持续时间与rom之间的非线性关系。结果:纳入51例患者进行分析。DWSP去除的平均时间为110天(范围59-182天)。DWSP移除后的中位随访时间为11.7个月(四分位数间距为8.2个月至1.8年)。DWSP持续时间与视觉模拟量表(P = 0.11)、并发症发生率(P = 0.45)、径向倾角(P = 0.57)、径向高度(P = 0.74)、掌侧倾角(P = 0.13)无显著相关性。在控制年龄、性别、多发创伤、随访时间和额外固定的情况下,逐块回归显示,DWSP bbb120天内旋后(P = 0.001)、旋前(P = < 0.001)和腕屈曲(P = 0.014)有统计学意义的减少。讨论:DWSP持续时间与腕关节活动度(屈曲、旋后和旋前)之间存在非线性关联。当DWSP持续时间大于120天时,在控制协变量时,与ROM呈负相关。当DWSP持续时间小于或等于120天时,与ROM无关。我们的研究结果表明,DWSP持续时间较长(bb0 120天)的患者更有可能出现活动范围限制;需要进一步的研究来确定超过120天的内固定本身、骨折或需要更长时间内固定的患者特定因素是否是导致这种运动限制的原因。证据水平:回顾性队列,四级。
{"title":"The Effect of Bridge Plate Duration on Range of Motion: A Breakpoint Modelling Approach for Distal Radius Fractures Treated With Dorsal Wrist Spanning Bridge Plate.","authors":"Jessica M Welch, Bradley J Lauck, Tyler S Pidgeon, Marc J Richard, Christopher S Klifto, Daniel J Lorenzana, David S Ruch","doi":"10.5435/JAAOS-D-24-00604","DOIUrl":"10.5435/JAAOS-D-24-00604","url":null,"abstract":"<p><strong>Background: </strong>Dorsal wrist spanning plate (DWSP) fixation is a technique used to treat distal radius fractures with severe metaphyseal comminution, diaphyseal extension, and other complex fracture patterns. One concern of this technique is the potential risk of stiffness due to prolonged immobilization. The purpose of our study was to examine the association of DWSP duration on range of motion (ROM) outcomes after plate removal.</p><p><strong>Methods: </strong>Patients who underwent DWSP fixation for distal radius fracture with greater than 6 months of follow-up after DWSP removal at a single institution were retrospectively identified. Patients with a concomitant upper extremity injury were excluded. The primary outcome of interest was ROM. Secondary outcomes included visual analog scale pain scores and radiographic measurements. A piecewise regression analysis was run to evaluate for a nonlinear relationship between DWSP duration and ROM.</p><p><strong>Results: </strong>Fifty-one patients were included for analysis. DWSP removal occurred at a mean of 110 days (range, 59-182 days). Median duration of follow-up after DWSP removal was 11.7 months (interquartile range = 8.2 months to 1.8 years). No significant association was observed between DWSP duration and visual analog scale ( P = 0.11), complication rate ( P = 0.45), radial inclination ( P = 0.57), radial height ( P = 0.74), or volar tilt ( P = 0.13). Piecewise regression demonstrated a statistically significant reduction in supination ( P = 0.001), pronation ( P = < 0.001), and wrist flexion ( P = 0.014) for DWSP >120 days when controlling for age, sex, polytrauma, duration of follow-up, and additional fixation.</p><p><strong>Discussion: </strong>There is a nonlinear association between DWSP duration and wrist ROM (flexion, supination, and pronation). When DWSP duration is longer than 120 days, there is a negative correlation with ROM when controlling for covariates. When DWSP duration is less than or equal to 120 days, there is no correlation with ROM. Our findings suggest that patients with longer duration of DWSP duration (>120 days) are more likely to have range-of-motion limitations; additional research is necessary to determine whether implant retention longer than 120 days by itself or fracture or patient-specific factors which require longer implant retention are the causative agents for this motion limitation.</p><p><strong>Level of evidence: </strong>Retrospective cohort, Level IV.</p>","PeriodicalId":51098,"journal":{"name":"Journal of the American Academy of Orthopaedic Surgeons","volume":" ","pages":"e52-e59"},"PeriodicalIF":2.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of the American Academy of Orthopaedic Surgeons
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