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Artificial Intelligence Promotes the Dunning Kruger Effect: Evaluating ChatGPT Answers to Frequently Asked Questions About Adolescent Idiopathic Scoliosis. 人工智能促进邓宁-克鲁格效应:评估 ChatGPT 对青少年特发性脊柱侧凸常见问题的回答。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-20 DOI: 10.5435/JAAOS-D-24-00297
Lambert T Li, Jeremy M Adelstein, Margaret A Sinkler, R Justin Mistovich

Introduction: Patients have long turned to the Internet for answers to common medical questions. As the ability to access information evolves beyond standard search engines, patients with adolescent idiopathic scoliosis (AIS) and their parents may use artificial intelligence chatbots such as ChatGPT as a new source of information.

Methods: Ten frequently asked questions regarding AIS were posed to ChatGPT. The accuracy and adequacy of the responses were graded as excellent not requiring clarification, satisfactory requiring minimal clarification, satisfactory requiring moderate clarification, and unsatisfactory requiring substantial clarification.

Results: ChatGPT gave one response that was excellent not requiring clarification, four responses that were satisfactory requiring minimal clarification, three responses that were satisfactory requiring moderate clarification, and two responses that were unsatisfactory requiring substantial clarification, with information about higher level, more complex areas of discussion such as surgical options being less accurate.

Conclusion: ChatGPT provides answers to FAQs about AIS that were generally accurate, although correction was needed on specific surgical treatments. Patients may be at risk of developing a Dunning-Kruger effect by proxy from the superficial and sometimes inaccurate information provided by ChatGPT on more complex aspects of AIS.

介绍:长期以来,患者一直在互联网上寻找常见医疗问题的答案。随着获取信息的能力超越了标准搜索引擎,青少年特发性脊柱侧弯症(AIS)患者及其家长可以使用人工智能聊天机器人(如 ChatGPT)作为新的信息来源:方法:向 ChatGPT 提出了 10 个有关 AIS 的常见问题。回答的准确性和充分性被分为不需要澄清的优秀、需要少量澄清的满意、需要适度澄清的满意和需要大量澄清的不满意:结果:ChatGPT 提供了一个不需要澄清的优秀回复,四个需要最低程度澄清的满意回复,三个需要中等程度澄清的满意回复,两个需要实质性澄清的不满意回复,其中关于更高层次、更复杂的讨论领域(如手术方案)的信息准确性较低:结论:ChatGPT 提供的有关 AIS 的常见问题答案总体上是准确的,但在具体的手术治疗方法上还需要修正。由于 ChatGPT 提供的有关 AIS 更复杂方面的信息过于肤浅,有时甚至不准确,因此患者可能会有产生邓宁-克鲁格效应的风险。
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引用次数: 0
Evaluating the 2023 Standardized Letter of Recommendation Form in Applications to Orthopaedic Surgery Residency. 评估骨科住院医师申请中的 2023 年标准化推荐信表格。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-18 DOI: 10.5435/JAAOS-D-24-00234
Hyunwoo P Kang, Jacob R Ball, Fergui Hernandez, Tara Shelby, Jay R Lieberman

Background: Successfully matching into orthopaedic surgery residency is a challenging endeavor due to the limited number of available positions. Implementation of the Standard Letter of Recommendation (SLOR) in 2017 was intended to allow better comparisons between applicants; however, the form suffered from notable rank inflation ultimately requiring introduction of an updated SLOR for the 2023 to 2024 application cycle. The purpose of this study was to evaluate whether the 2023 SLOR improves on deficiencies of the 2017 SLOR.

Methods: Applications submitted to our institution during the 2023 to 2024 orthopaedic surgery residency application cycle were analyzed. Applicant objective metrics were collected, including US Medical Licensing Exam scores, clerkship grades, AΩA status, and research productivity. Scores for each domain of the 2023 SLOR forms were recorded. Mean scores were calculated for each question, and cumulative scores per SLOR were determined. Intraclass correlation coefficients were determined per applicant and evaluator. The Spearman rank correlation coefficient was calculated for comparison of SLOR cumulative scores and objective metrics.

Results: Three hundred sixty-eight applications were reviewed, and 743 2023 SLORs were submitted in conjunction with these applications. Most of the 2023 SLORs (n = 399, 53.70%) had cumulative scores placing applicants in at least the 90th percentile. Furthermore, 267 evaluators (72.36%) consistently gave scores of 99s and 10s for each question. Intraclass correlation coefficients were rated as fair to moderate agreement between evaluators for each applicant. Objective applicant metrics did not meaningfully correlate with SLOR cumulative scores.

Discussion: The 2023 SLOR demonstrated notable rank inflation with only 22.7% of applicants receiving a score of less than 7 on any domain. By contrast, 69.9% of applicants received a score of "rare, perfect gem" on at least one domain of the form. We encourage the American Orthopaedic Association Council of Orthopaedic Residency Director to continue to improve the form and provide guidance to residency program leadership on proper use of the grading system.

背景:由于可用职位数量有限,成功匹配骨科外科住院医师是一项具有挑战性的工作。2017 年实施的标准推荐信(SLOR)旨在更好地比较申请人之间的情况;然而,该表格存在明显的排名膨胀问题,最终需要在 2023 至 2024 年申请周期引入更新的 SLOR。本研究旨在评估2023年SLOR是否改进了2017年SLOR的不足之处:分析了本机构在 2023 至 2024 年骨科住院医师申请周期内提交的申请。收集了申请者的客观指标,包括美国医学执照考试分数、实习成绩、AΩA状态和研究效率。记录了2023年SLOR表格中每个领域的得分。计算每个问题的平均分,并确定每个 SLOR 的累计得分。根据申请人和评估者确定类内相关系数。计算斯皮尔曼等级相关系数,以比较 SLOR 累计得分和客观指标:共审查了 368 份申请,与这些申请一起提交的 2023 SLOR 有 743 份。大多数 2023 SLOR(n = 399,53.70%)的累计分数至少位于第 90 百分位数。此外,267 名评估员(72.36%)在每个问题上都给出了 99 分和 10 分。每个申请人的评估者之间的类内相关系数被评为一般至中等。客观的申请人指标与 SLOR 累计分数之间没有意义上的相关性:2023 年 SLOR 显示出明显的排名膨胀,只有 22.7% 的申请人在任何领域的得分低于 7 分。相比之下,69.9%的申请人至少在一个领域获得了 "罕见的完美宝石 "的分数。我们鼓励美国骨科协会骨科住院医师指导委员会继续改进该表格,并为住院医师项目领导提供正确使用评分系统的指导。
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引用次数: 0
2023 American Academy of Orthopaedic Surgeons Management of Osteoarthritis of the Hip Evidence-Based Clinical Practice Guideline: Case Studies. 2023 美国矫形外科学会髋关节骨性关节炎循证临床实践指南:病例研究。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-18 DOI: 10.5435/JAAOS-D-24-00427
Sumon Nandi, Charles P Hannon, Yale Fillingham

The American Academy of Orthopaedic Surgeons, together with The Hip Society, American Association of Hip and Knee Surgeons, American College of Radiology, and American Physical Therapy Association, recently released the updated 2023 Management of Osteoarthritis of the Hip Evidence-Based Clinical Practice Guidelines. 8 recommendations and 9 options comprise these guidelines intended to optimize treatment outcomes in a patient population that is growing exponentially over time. In this article, we present case studies that illustrate utilization of the clinical practice guideline workgroup's evidence-based recommendations in clinical practice.

美国骨科外科医生学会与髋关节协会、美国髋关节和膝关节外科医生协会、美国放射学会和美国理疗协会最近共同发布了最新的《2023 年髋关节骨性关节炎循证临床实践指南》。这些指南包含 8 项建议和 9 种方案,旨在优化随着时间推移而呈指数增长的患者群体的治疗效果。在本文中,我们将通过案例研究来说明临床实践指南工作组的循证建议在临床实践中的应用。
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引用次数: 0
Implicit Race Bias in Pediatric Patients: Understanding Patient Perspectives. 儿科患者的隐性种族偏见:了解患者的观点。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-17 DOI: 10.5435/JAAOS-D-24-00307
Taylor M Adams, Ryan Guzek, Ravinder Brar

Introduction: Implicit racial bias has been well studied in adults, including among orthopaedic surgeons, through the Implicit Association Test (IAT). Recent studies suggest implicit race bias is also present among children. Explicit racial preference has been studied in children through The Clark Doll Test since the 1930s. The purpose of this study was to determine whether implicit and explicit racial biases are present among pediatric orthopaedic patients.

Methods: A prospective, cross-sectional survey was administered to pediatric orthopaedic patients aged 7 to 18 years at clinics in a tertiary pediatric hospital setting. The survey included a Clark Doll Test to determine whether pediatric patients expressed explicit bias, followed by a race IAT to determine whether pediatric patients expressed implicit bias. Preference and magnitude of implicit bias as demonstrated on the IAT was calculated using standard D-scores.

Results: A total of 96 patients were consented and included in this study. Overall, pediatric patients demonstrated a slight pro-White implicit bias (M = 0.22) on IAT testing. Pediatric patients who identified as White or European American and Hispanic or Latinx both had the strongest pro-White implicit bias (M = 0.35). Patients who identified as Black or African American demonstrated no implicit racial bias (M = -0.13) on IAT testing. No notable explicit bias was observed in participants of any racial background.

Discussion: This study contributes evidence that pediatric orthopaedic patients express implicit racial bias on IAT testing, with an overall slight pro-White bias. It also provides insight into the dissociation of implicit and explicit racial bias in childhood and adolescence.

Conclusion: We encourage future research on implicit bias among pediatric patients in the orthopaedic community to provide a better understanding and possible solutions to bias-related challenges in health care.

介绍:通过内隐联想测验(IAT),对成人(包括矫形外科医生)的内隐种族偏见进行了深入研究。最近的研究表明,儿童中也存在内隐种族偏见。自 20 世纪 30 年代以来,通过克拉克娃娃测试对儿童的显性种族偏好进行了研究。本研究旨在确定儿科骨科患者中是否存在内隐和外显的种族偏见:方法:在一家三级儿科医院的诊所对 7 至 18 岁的小儿骨科患者进行了一项前瞻性横断面调查。调查包括克拉克娃娃测试(Clark Doll Test),以确定儿科患者是否表达了显性偏见,然后是种族内隐偏差测试(race IAT),以确定儿科患者是否表达了隐性偏见。使用标准 D 分计算 IAT 所显示的隐性偏见的偏好和程度:共有 96 名患者同意并参与本研究。总体而言,儿科患者在 IAT 测试中表现出轻微的亲白人内隐偏差(M = 0.22)。被认定为白人或欧洲裔美国人以及西班牙裔或拉丁裔的儿科患者都具有最强烈的亲白人隐性偏见(M = 0.35)。被认定为黑人或非裔美国人的患者在 IAT 测试中没有表现出内隐性种族偏见(M = -0.13)。在任何种族背景的参与者身上都没有观察到明显的显性偏见:本研究证明,儿科骨科患者在 IAT 测试中表现出内隐性种族偏见,总体上略微倾向于白人。结论:我们鼓励今后对儿童骨科患者的内隐种族偏见进行研究:我们鼓励今后对骨科社区儿科患者的隐性偏见进行研究,以便更好地了解医疗保健中与偏见相关的挑战并提供可能的解决方案。
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引用次数: 0
One-Stage Versus Two-Stage Revision Surgery for Periprosthetic Hip Infection: An Updated Systematic Review and Meta-Analysis of Clinical Outcomes. 髋关节假体周围感染的一期与二期翻修手术:临床结果的最新系统回顾和荟萃分析。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-17 DOI: 10.5435/JAAOS-D-24-00456
José María Lamo-Espinosa, Gonzalo Mariscal, Jorge Gómez-Álvarez, Lluís Font-Vizcarra, Jose Luis Del Pozo, Mikel San-Julián

Introduction: The primary objective of this meta-analysis was to evaluate and compare the functional outcomes, postoperative reinfection rates, and complication rates in patients undergoing one-stage versus two-stage surgical revision for periprosthetic hip infection.

Methods: The study population included adult patients who had undergone revision hip arthroplasty. Comparative studies have compared two-stage and one-stage revision strategies. Searches were conducted using the major databases. Review Manager software was used to estimate the effects. A sensitivity analysis was also conducted.

Results: Nine cohort studies including 2,502 hips were included. The success rate did not show significant differences between the groups (odds ratio [OR] 0.42, 95% confidence interval 0.05 to 3.37). No difference was noted in reinfection (OR 0.81, 95% CI 0.56-1.19). Life quality per Harris Hip Score was higher for one-stage revision strategies (mean difference [MD] 9.00, 95% CI 2.23-15.78). No differences were noted in mortality, aseptic loosening, or revision rates. Age (MD 2.32, 95% CI 1.34-3.29) and body mass index (BMI) (MD 1.88, 95% CI 0.38-3.38) were lower in the two-stage group. Sinus tract presence was higher in the one-stage group (OR 1.44, 95% CI 1.05-1.95). Paprosky I acetabulum was higher in the one-stage group, and Paprosky III was higher in the two-stage group.

Conclusions: The results did not demonstrate notable clinical differences between one-stage and two-stage hip arthroplasties, regardless of the treated microorganism. However, the quality of life may be somewhat better in the one-stage group. Age, body mass index, and Paprosky classification are factors that influence procedure selection.

简介:这项荟萃分析的主要目的是评估和比较因髋关节假体周围感染而接受一期与二期翻修手术的患者的功能预后、术后再感染率和并发症发生率:研究对象包括接受髋关节翻修手术的成年患者。比较研究对两阶段和一阶段翻修策略进行了比较。使用主要数据库进行检索。使用Review Manager软件估算效果。还进行了敏感性分析:结果:共纳入九项队列研究,包括 2,502 个髋关节。各组间的成功率无明显差异(几率比[OR] 0.42,95% 置信区间 0.05 至 3.37)。在再感染方面也无差异(OR 0.81,95% 置信区间 0.56-1.19)。按哈里斯髋关节评分计算,单阶段翻修策略的生活质量更高(平均差 [MD] 9.00,95% CI 2.23-15.78)。死亡率、无菌性松动或翻修率方面没有差异。两期手术组的年龄(MD 2.32,95% CI 1.34-3.29)和体重指数(BMI)(MD 1.88,95% CI 0.38-3.38)较低。一期手术组中出现窦道的比例更高(OR 1.44,95% CI 1.05-1.95)。一期手术组中 Paprosky I 型髋臼的比例较高,二期手术组中 Paprosky III 型髋臼的比例较高:结论:无论治疗的微生物是什么,单阶段髋关节置换术和两阶段髋关节置换术的临床差异并不明显。不过,一期组的生活质量可能更好一些。年龄、体重指数和Paprosky分类是影响手术选择的因素。
{"title":"One-Stage Versus Two-Stage Revision Surgery for Periprosthetic Hip Infection: An Updated Systematic Review and Meta-Analysis of Clinical Outcomes.","authors":"José María Lamo-Espinosa, Gonzalo Mariscal, Jorge Gómez-Álvarez, Lluís Font-Vizcarra, Jose Luis Del Pozo, Mikel San-Julián","doi":"10.5435/JAAOS-D-24-00456","DOIUrl":"https://doi.org/10.5435/JAAOS-D-24-00456","url":null,"abstract":"<p><strong>Introduction: </strong>The primary objective of this meta-analysis was to evaluate and compare the functional outcomes, postoperative reinfection rates, and complication rates in patients undergoing one-stage versus two-stage surgical revision for periprosthetic hip infection.</p><p><strong>Methods: </strong>The study population included adult patients who had undergone revision hip arthroplasty. Comparative studies have compared two-stage and one-stage revision strategies. Searches were conducted using the major databases. Review Manager software was used to estimate the effects. A sensitivity analysis was also conducted.</p><p><strong>Results: </strong>Nine cohort studies including 2,502 hips were included. The success rate did not show significant differences between the groups (odds ratio [OR] 0.42, 95% confidence interval 0.05 to 3.37). No difference was noted in reinfection (OR 0.81, 95% CI 0.56-1.19). Life quality per Harris Hip Score was higher for one-stage revision strategies (mean difference [MD] 9.00, 95% CI 2.23-15.78). No differences were noted in mortality, aseptic loosening, or revision rates. Age (MD 2.32, 95% CI 1.34-3.29) and body mass index (BMI) (MD 1.88, 95% CI 0.38-3.38) were lower in the two-stage group. Sinus tract presence was higher in the one-stage group (OR 1.44, 95% CI 1.05-1.95). Paprosky I acetabulum was higher in the one-stage group, and Paprosky III was higher in the two-stage group.</p><p><strong>Conclusions: </strong>The results did not demonstrate notable clinical differences between one-stage and two-stage hip arthroplasties, regardless of the treated microorganism. However, the quality of life may be somewhat better in the one-stage group. Age, body mass index, and Paprosky classification are factors that influence procedure selection.</p>","PeriodicalId":51098,"journal":{"name":"Journal of the American Academy of Orthopaedic Surgeons","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personal Financial Literacy for the Orthopaedic Trainee and Early Career Surgeon: A Review of the Basics. 矫形外科实习医生和早期职业外科医生的个人财务知识:基础知识回顾。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-17 DOI: 10.5435/JAAOS-D-23-01260
Michael J Kutschke, Paul D Fadale

Personal finance is a topic that has historically been shunned as a point of conversation in academia, often avoided and seldom discussed in medical training. However, this aversion leaves trainees and early career surgeons to make complex financial decisions without sufficient understanding while simultaneously facing the pressures of building an orthopaedic practice-a recipe destined for burnout. This simple review serves to equip young orthopaedic surgeons with the fundamental personal financial concepts essential for making wise financial choices early in their careers. Prompt elimination of all high-interest consumer debt and devising a strategy to address student loans are crucial first steps in establishing the foundation for personal financial success. Progressing through training and entering practice bring about enhanced personal discretionary funds that are most effectively deployed through consistent budgeting and automated saving strategies. Malpractice, disability, and life insurances are keys to protecting current and future earnings as well as preventing financial catastrophe. Augmenting these items with a functional understanding of taxation systems, tax diversification, and asset protection is essential to recognize in the early years of practice to set the trajectory for financial independence and a well-deserved retirement.

在学术界,个人理财历来是一个避而不谈的话题,在医学培训中经常被回避,也很少被讨论。然而,这种回避使受训者和职业生涯初期的外科医生在没有充分了解的情况下做出复杂的财务决定,同时还要面对建立骨科实践的压力,这注定会导致职业倦怠。这篇简单的评论将帮助年轻的骨科医生掌握基本的个人财务概念,从而在职业生涯早期做出明智的财务选择。及时还清所有高息消费债务并制定解决学生贷款问题的策略,是为个人财务成功奠定基础的关键第一步。通过培训和实习,个人可自由支配的资金会增加,通过持续的预算编制和自动储蓄策略,可以最有效地利用这些资金。医疗事故、残疾和人寿保险是保护当前和未来收入以及防止财务灾难的关键。在执业初期,通过对税收制度、税收多样化和资产保护的实用性了解来补充这些项目,对于确定财务独立和当之无愧的退休生活的轨迹至关重要。
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引用次数: 0
Primary Anterior Cruciate Ligament Injury: Extrinsic and Intrinsic Risk Factors. 原发性前十字韧带损伤:外在和内在风险因素。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-17 DOI: 10.5435/JAAOS-D-24-00341
Nicholas A Apseloff, Jonathan D Hughes, Brian M Devitt, Volker Musahl

Anterior cruciate ligament (ACL) injuries continue to increase in incidence despite extensive research into prevention strategies. Many extrinsic and intrinsic risk factors for sustaining ACL injuries have been identified and continue to be investigated. Extrinsic risk factors for ACL injury relate to the athlete's environment, such as the shoe-surface interaction, weather conditions, and sport played. Intrinsic risk factors relate to the athlete's sex, hormones, knee anatomy, landing and pivoting biomechanics, and neuromuscular control. Recent research has highlighted the role of the bony morphology of the proximal tibia and distal femur on primary ACL injury risk, as well as the risk for ACL graft failure. Sex differences in bony and ligamentous morphology of the knee, neuromuscular control, and hormonal factors, such as serum relaxin levels and variations within the menstrual cycle, have been correlated with a higher risk of noncontact primary ACL injuries in female athletes compared with male athletes.

尽管对预防策略进行了广泛的研究,但前十字韧带(ACL)损伤的发生率仍在不断上升。许多导致前十字韧带损伤的外在和内在风险因素已被确认,并将继续得到研究。前十字韧带损伤的外在风险因素与运动员所处的环境有关,如鞋面的相互作用、天气条件和所从事的运动。内在风险因素与运动员的性别、荷尔蒙、膝关节解剖、着地和旋转生物力学以及神经肌肉控制有关。最近的研究强调了胫骨近端和股骨远端骨骼形态对十字韧带原发性损伤风险的作用,以及十字韧带移植失败的风险。与男性运动员相比,女性运动员在膝关节骨骼和韧带形态、神经肌肉控制以及荷尔蒙因素(如血清松弛素水平和月经周期变化)方面的性别差异与更高的非接触性前交叉韧带损伤风险相关。
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引用次数: 0
Osteoporosis Evaluation and Management in Spine Surgery. 脊柱手术中的骨质疏松症评估和管理。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-15 Epub Date: 2024-07-30 DOI: 10.5435/JAAOS-D-24-00311
Steven J Girdler, Matthew H Lindsey, Arjun S Sebastian, Ahmad Nassr

Osteoporosis is a global health problem affecting over 200 million people worldwide and 54 million adults in the United States. Approximately half of all postmenopausal women will have an osteoporosis-related fracture during their lifetime. In the United States, the direct medical cost related to osteoporosis is expected to exceed $25 billion by 2025. Management of osteoporosis in vertebral fractures and elective spine surgery is of the utmost concern, given the high prevalence of osteoporosis in the general population and the increased risk of complication in this population. New pharmacologic treatment options such as anabolic medications and diagnostic tools including Hounsfield unit measurements on routine computed tomography scans are available to orthopaedic and spinal surgeons to help best manage this condition. This review serves as an update to diagnosis, management, and treatment of patients with osteoporosis undergoing spinal surgery.

骨质疏松症是一个全球性的健康问题,影响着全球 2 亿多人和美国 5400 万成年人。大约一半的绝经后妇女在其一生中会发生与骨质疏松症相关的骨折。在美国,预计到 2025 年,与骨质疏松症相关的直接医疗费用将超过 250 亿美元。鉴于骨质疏松症在普通人群中的高发病率以及该人群并发症风险的增加,在脊椎骨折和脊柱择期手术中对骨质疏松症的管理是最值得关注的问题。骨科和脊柱外科医生可以使用新的药物治疗方案(如同化药物)和诊断工具(包括常规计算机断层扫描中的 Hounsfield 单位测量值)来帮助更好地控制这种情况。本综述将为接受脊柱手术的骨质疏松症患者提供最新的诊断、管理和治疗方法。
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引用次数: 0
Midterm Outcomes of Multimodal Approach to Treating Severe Scoliosis in Patients With Osteogenesis Imperfecta. 治疗成骨不全症患者严重脊柱侧凸的多模式方法的中期疗效。
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-15 Epub Date: 2024-07-10 DOI: 10.5435/JAAOS-D-23-00889
Yusuke Hori, Tyler C McDonald, Patrick Thornley, Luiz Carlos Almeida da Silva, Burak Kaymaz, Kenneth J Rogers, Petya K Yorgova, Michael B Bober, Ricki Carroll, Richard W Kruse, Jeanne M Franzone, Suken A Shah

Introduction: The surgical management of severe scoliosis in patients with osteogenesis imperfecta (OI) is challenging because of curve rigidity, small stature, and inherent bone fragility. This study evaluated the midterm outcomes of our multimodal approach to address these issues, integrating perioperative bisphosphonate therapy, preoperative/intraoperative traction, various osteotomies, segmental pedicle screw instrumentation with cement augmentation, and bone morphogenetic protein-2 application.

Methods: A single-center retrospective review of 30 patients (average age 14.1 ± 2.2 years; 18 were female) diagnosed with OI and scoliosis was conducted. These patients underwent posterior spinal fusion between 2008 and 2020 and completed a minimum follow-up of 2 years. We measured radiographic parameters at each visit and reviewed the incidence of complications. A mixed-effects model was used to evaluate changes in radiographic parameters from preoperative measurements to the first and latest follow-ups.

Results: The patient cohort consisted of 2 individuals with type I OI, 20 with type III, 6 with type IV, and 2 with other types (types V and VIII). Surgical intervention led to a notable improvement in the major curve magnitude from 76° to 36°, with no notable correction loss. In addition, the minor curve, apical vertical translation, lowest instrumented vertebra tilt, and pelvic obliquity were also improved. In the sagittal plane, thoracic kyphosis and lumbar lordosis remained unchanged while thoracolumbar kyphosis markedly improved. Two patients experienced proximal junctional kyphosis with screw pullout, one of whom required revision surgery. One patient developed a superficial infection that was successfully treated with oral antibiotics. No instances of neurologic deficits or cement extravasation were observed.

Discussion: This study demonstrated the effectiveness and safety of our multimodal approach to treating scoliosis in patients with OI, achieving a 53% major curve correction with minimal complications over 2-year follow-up. These findings provide notable insights into managing scoliosis in this population.

Level of evidence: Level IV (case series).

导言:对成骨不全症(OI)患者的严重脊柱侧弯进行手术治疗具有挑战性,因为患者的曲线僵硬、身材矮小、骨质脆弱。本研究评估了我们采用多模式方法解决这些问题的中期效果,包括围手术期双磷酸盐治疗、术前/术中牵引、各种截骨术、节段椎弓根螺钉器械加骨水泥增强以及骨形态发生蛋白-2应用:对 30 名确诊为 OI 和脊柱侧凸的患者(平均年龄为 14.1 ± 2.2 岁;18 名女性)进行了单中心回顾性研究。这些患者在 2008 年至 2020 年期间接受了脊柱后路融合术,并完成了至少 2 年的随访。我们测量了每次就诊时的放射学参数,并回顾了并发症的发生率。我们使用混合效应模型来评估从术前测量到首次和最近一次随访期间放射学参数的变化:患者队列中包括 2 名 I 型 OI 患者、20 名 III 型患者、6 名 IV 型患者和 2 名其他类型患者(V 型和 VIII 型)。手术治疗显著改善了患者的主要弧度,从 76° 降至 36°,且没有明显的矫正损失。此外,小曲线、顶端垂直平移、最低器械椎体倾斜和骨盆倾斜也得到了改善。在矢状面,胸椎后凸和腰椎前凸保持不变,而胸腰椎后凸明显改善。两名患者因螺钉脱出而出现近端交界处驼背,其中一人需要进行翻修手术。一名患者出现表皮感染,经口服抗生素治疗后成功治愈。未发现神经功能缺损或骨水泥外渗的情况:这项研究证明了我们采用多模式方法治疗OI患者脊柱侧凸的有效性和安全性,在两年的随访中,主要曲线矫正率达到53%,并发症极少。这些研究结果为该人群脊柱侧凸的治疗提供了值得注意的见解:证据级别:IV级(病例系列)
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引用次数: 0
Preoperative Electrodiagnostic Study Findings Differ Between Patients With Double-crush Syndrome and Carpal Tunnel Syndrome: A Propensity Matched Analysis. 双挤压综合征和腕管综合征患者术前电诊断研究结果的差异:倾向匹配分析
IF 2.6 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-15 Epub Date: 2024-05-08 DOI: 10.5435/JAAOS-D-24-00056
Nicholas B Pohl, Rajkishen Narayanan, Parker L Brush, Yunsoo Lee, Rabia Qureshi, Arun Kanhere, M Lauren Micou, Sebastian I Fras, Ian David Kaye, John J Mangan, Mark F Kurd, Michael J Mehnert, Jose A Canseco, Alan S Hilibrand, Alexander R Vaccaro, Christopher K Kepler, Gregory D Schroeder

Introduction: Double-crush syndrome (DCS) represents a condition that involves peripheral nerve compression in combination with spinal nerve root impingement. The purpose of this study was to compare electrodiagnostic study (EDS) results in patients undergoing carpal tunnel release (CTR) for carpal tunnel syndrome with those undergoing both CTR and anterior cervical diskectomy and fusion for DCS.

Methods: Patients receiving an isolated CTR were compared with those undergoing CTR and anterior cervical diskectomy and fusion within two years of CTR. The latter group was defined as our DCS cohort. Electrodiagnostic study results were collected which included sensory and motor nerve conduction data as well as electromyogram (EMG) findings. All electrodiagnostic studies were done before CTR in both sets of patients.

Results: Fifty-four patients with DCS and 137 CTR-only patients were included. Patients with DCS were found to have decreased sensory onset latency (3.51 vs 4.01; P = 0.015) and peak latency (4.25 vs 5.17; P = 0.004) compared with the CTR-only patients. Patients with DCS had slower wrist motor velocity (30.5 vs 47.7; P = 0.012), decreased elbow motor latency (9.62 vs 10.6; P = 0.015), and faster elbow motor velocity (56.0 vs 49.4; P = 0.031). EMG results showed that patients with DCS were more likely to have positive findings in the biceps (31.9% vs 1.96%; P < 0.001) and triceps (24.4% vs 2.97%; P < 0.001), but not abductor pollicis brevis (APB) (45.7% vs 37.9%; P = 0.459).

Conclusion: We identified changes on EDS between patients with and without DCS. In patients with DCS, sensory nerve studies showed shorter peak and onset latency than in CTR-only patients. Interestingly, DCS and CTR-only patients had different patterns of wrist and elbow motor nerve conduction. Providers observing positive EMG findings proximal to the APB should raise their suspicion for possible cervical radiculopathy and when present with carpal tunnel syndrome-like symptoms, should also consider DCS in their diagnostic differential.

简介双挤压综合征(DCS)是一种周围神经受压并伴有脊神经根撞击的病症。本研究旨在比较接受腕管松解术(CTR)治疗腕管综合征的患者与同时接受CTR和颈椎前路椎间盘切除术和融合术治疗双挤压综合征的患者的电诊断研究(EDS)结果:将单独接受腕管松解术的患者与在腕管松解术后两年内同时接受腕管松解术和颈椎前路椎间盘切除及融合术的患者进行比较。后一组患者被定义为我们的 DCS 队列。收集的电诊断研究结果包括感觉和运动神经传导数据以及肌电图(EMG)结果。两组患者的所有电诊断检查均在 CTR 之前完成:结果:纳入了 54 名 DCS 患者和 137 名仅接受 CTR 的患者。与仅接受 CTR 的患者相比,DCS 患者的感觉起始潜伏期(3.51 vs 4.01;P = 0.015)和峰值潜伏期(4.25 vs 5.17;P = 0.004)均有所缩短。DCS患者的腕部运动速度较慢(30.5 vs 47.7;P = 0.012),肘部运动潜伏期较短(9.62 vs 10.6;P = 0.015),肘部运动速度较快(56.0 vs 49.4;P = 0.031)。EMG结果显示,DCS患者的肱二头肌(31.9% vs 1.96%;P <0.001)和肱三头肌(24.4% vs 2.97%;P <0.001)出现阳性结果的几率更高,但股骨外展肌(APB)(45.7% vs 37.9%;P = 0.459)却不高:我们发现了患有和未患有 DCS 的患者在 EDS 上的变化。与仅有 CTR 的患者相比,DCS 患者的感觉神经研究显示出更短的峰值和起始潜伏期。有趣的是,DCS 和纯 CTR 患者的腕部和肘部运动神经传导模式不同。医务人员在观察到APB近端EMG阳性结果时,应怀疑可能存在颈椎病,当出现类似腕管综合征的症状时,也应在诊断鉴别中考虑DCS。
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Journal of the American Academy of Orthopaedic Surgeons
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