Pub Date : 2023-12-01Epub Date: 2023-10-27DOI: 10.1089/big.2022.0178
Megan Schröder, Sam H A Muller, Eleni Vradi, Johanna Mielke, Yvonne M F Lim, Fabrice Couvelard, Menno Mostert, Stefan Koudstaal, Marinus J C Eijkemans, Christoph Gerlinger
Sharing individual patient data (IPD) is a simple concept but complex to achieve due to data privacy and data security concerns, underdeveloped guidelines, and legal barriers. Sharing IPD is additionally difficult in big data-driven collaborations such as Bigdata@Heart in the Innovative Medicines Initiative, due to competing interests between diverse consortium members. One project within BigData@Heart, case study 1, needed to pool data from seven heterogeneous data sets: five randomized controlled trials from three different industry partners, and two disease registries. Sharing IPD was not considered feasible due to legal requirements and the sensitive medical nature of these data. In addition, harmonizing the data sets for a federated data analysis was difficult due to capacity constraints and the heterogeneity of the data sets. An alternative option was to share summary statistics through contingency tables. Here it is demonstrated that this method along with anonymization methods to ensure patient anonymity had minimal loss of information. Although sharing IPD should continue to be encouraged and strived for, our approach achieved a good balance between data transparency while protecting patient privacy. It also allowed a successful collaboration between industry and academia.
{"title":"Sharing Medical Big Data While Preserving Patient Confidentiality in Innovative Medicines Initiative: A Summary and Case Report from BigData@Heart.","authors":"Megan Schröder, Sam H A Muller, Eleni Vradi, Johanna Mielke, Yvonne M F Lim, Fabrice Couvelard, Menno Mostert, Stefan Koudstaal, Marinus J C Eijkemans, Christoph Gerlinger","doi":"10.1089/big.2022.0178","DOIUrl":"10.1089/big.2022.0178","url":null,"abstract":"<p><p>Sharing individual patient data (IPD) is a simple concept but complex to achieve due to data privacy and data security concerns, underdeveloped guidelines, and legal barriers. Sharing IPD is additionally difficult in big data-driven collaborations such as Bigdata@Heart in the Innovative Medicines Initiative, due to competing interests between diverse consortium members. One project within BigData@Heart, case study 1, needed to pool data from seven heterogeneous data sets: five randomized controlled trials from three different industry partners, and two disease registries. Sharing IPD was not considered feasible due to legal requirements and the sensitive medical nature of these data. In addition, harmonizing the data sets for a federated data analysis was difficult due to capacity constraints and the heterogeneity of the data sets. An alternative option was to share summary statistics through contingency tables. Here it is demonstrated that this method along with anonymization methods to ensure patient anonymity had minimal loss of information. Although sharing IPD should continue to be encouraged and strived for, our approach achieved a good balance between data transparency while protecting patient privacy. It also allowed a successful collaboration between industry and academia.</p>","PeriodicalId":51314,"journal":{"name":"Big Data","volume":" ","pages":"399-407"},"PeriodicalIF":4.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10733752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61566098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yvonne Nartey, C. Crooks, Joe West, Timothy R. Card, Laila J. Tata
{"title":"The incidence and prevalence of coeliac disease in the United Kingdom","authors":"Yvonne Nartey, C. Crooks, Joe West, Timothy R. Card, Laila J. Tata","doi":"10.1370/afm.22.s1.5051","DOIUrl":"https://doi.org/10.1370/afm.22.s1.5051","url":null,"abstract":"","PeriodicalId":51314,"journal":{"name":"Big Data","volume":"18 1","pages":""},"PeriodicalIF":4.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139303896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in Reasons for Visits to Primary Care as a Result of the COVID-19 Pandemic: by INTRePID","authors":"Karen Tu, M. Lapadula","doi":"10.1370/afm.22.s1.5425","DOIUrl":"https://doi.org/10.1370/afm.22.s1.5425","url":null,"abstract":"","PeriodicalId":51314,"journal":{"name":"Big Data","volume":"11 1","pages":""},"PeriodicalIF":4.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139301044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William Curry, Wen-Jan Tuan, Qiushi Chen, Andrew Chung
{"title":"Breast cancer screening during the COVID-19 Pandemic in the United States: Results from real-world health records data","authors":"William Curry, Wen-Jan Tuan, Qiushi Chen, Andrew Chung","doi":"10.1370/afm.22.s1.4885","DOIUrl":"https://doi.org/10.1370/afm.22.s1.4885","url":null,"abstract":"","PeriodicalId":51314,"journal":{"name":"Big Data","volume":"48 1","pages":""},"PeriodicalIF":4.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139292120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tarin Clay, Melissa Filippi, Elise Robertson, Cory B. Lutgen, Elisabeth F. Callen
{"title":"A Novel Method for Utilizing Electronic Health Record Data in Condition-specific Research","authors":"Tarin Clay, Melissa Filippi, Elise Robertson, Cory B. Lutgen, Elisabeth F. Callen","doi":"10.1370/afm.22.s1.4955","DOIUrl":"https://doi.org/10.1370/afm.22.s1.4955","url":null,"abstract":"","PeriodicalId":51314,"journal":{"name":"Big Data","volume":"12 1","pages":""},"PeriodicalIF":4.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139294842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chance R. Strenth, David Schneider, U. Sambamoorthi, Sravan Mattevada, Kimberly Fulda, Bhaskar Thakur, Anna Espinoza
{"title":"Harmonized Healthcare Database across Family Medicine Institutions","authors":"Chance R. Strenth, David Schneider, U. Sambamoorthi, Sravan Mattevada, Kimberly Fulda, Bhaskar Thakur, Anna Espinoza","doi":"10.1370/afm.22.s1.5404","DOIUrl":"https://doi.org/10.1370/afm.22.s1.5404","url":null,"abstract":"","PeriodicalId":51314,"journal":{"name":"Big Data","volume":"14 1","pages":""},"PeriodicalIF":4.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139291188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Winston R. Liaw, Ben King, Omolola E. Adepoju, Jiangtao Luo, Ioannis Kakadiaris, Todd Prewitt, Jessica Dobbins, Pete Womack
{"title":"Identifying the Factors Associated with the Accumulation of Diabetes Complications to Inform a Prediction Tool","authors":"Winston R. Liaw, Ben King, Omolola E. Adepoju, Jiangtao Luo, Ioannis Kakadiaris, Todd Prewitt, Jessica Dobbins, Pete Womack","doi":"10.1370/afm.22.s1.5071","DOIUrl":"https://doi.org/10.1370/afm.22.s1.5071","url":null,"abstract":"","PeriodicalId":51314,"journal":{"name":"Big Data","volume":"23 1","pages":""},"PeriodicalIF":4.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139291940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01Epub Date: 2022-01-24DOI: 10.1089/big.2021.0274
Afzal Badshah, Ateeqa Jalal, Umar Farooq, Ghani-Ur Rehman, Shahab S Band, Celestine Iwendi
The cloud network is rapidly growing due to a massive increase in interconnected devices and the emergence of different technologies such as the Internet of things, fog computing, and artificial intelligence. In response, cloud computing needs reliable dealings among the service providers, brokers, and consumers. The existing cloud monitoring frameworks such as Amazon Cloud Watch, Paraleap Azure Watch, and Rack Space Cloud Kick work under the control of service providers. They work fine; however, this may create dissatisfaction among customers over Service Level Agreement (SLA) violations. Customers' dissatisfaction may drastically reduce the businesses of service providers. To cope with the earlier mentioned issue and get in line with cloud philosophy, Monitoring as a Service (MaaS), completely independent in nature, is needed for observing and regulating the cloud businesses. However, the existing MaaS frameworks do not address the comprehensive SLA for customer satisfaction and penalties management. This article proposes a reliable framework for monitoring the provider's services by adopting third-party monitoring services with clearcut SLA and penalties management. Since this framework monitors SLA as a cloud monitoring service, it is named as SLA-MaaS. On violations, it penalizes those who are found in breach of terms and condition enlisted in SLA. Simulation results confirmed that the proposed framework adequately satisfies the customers (as well as service providers). This helps in developing a trustworthy relationship among cloud partners and increases customer attention and retention.
由于互联设备的大量增加以及物联网、雾计算和人工智能等不同技术的出现,云网络正在迅速发展。作为回应,云计算需要服务提供商、经纪人和消费者之间的可靠交易。现有的云监控框架,如Amazon cloud Watch、Paraleap Azure Watch和Rack Space cloud Kick,在服务提供商的控制下工作。它们工作良好;然而,这可能会引起客户对违反服务水平协议(SLA)的不满。客户的不满可能会大大减少服务提供商的业务。为了解决前面提到的问题并符合云的理念,监控即服务(MaaS)在本质上是完全独立的,需要用于观察和监管云业务。然而,现有的MaaS框架没有解决客户满意度和处罚管理的全面SLA问题。本文提出了一个可靠的框架,通过采用具有clearcut SLA和惩罚管理的第三方监控服务来监控提供商的服务。由于该框架将SLA作为云监控服务进行监控,因此将其命名为SLA-MaaS。关于违规行为,它惩罚那些被发现违反苏丹解放军招募的条款和条件的人。仿真结果证实,所提出的框架充分满足了客户(以及服务提供商)的要求。这有助于在云合作伙伴之间建立值得信赖的关系,并提高客户的关注度和忠诚度。
{"title":"Service Level Agreement Monitoring as a Service: An Independent Monitoring Service for Service Level Agreements in Clouds.","authors":"Afzal Badshah, Ateeqa Jalal, Umar Farooq, Ghani-Ur Rehman, Shahab S Band, Celestine Iwendi","doi":"10.1089/big.2021.0274","DOIUrl":"10.1089/big.2021.0274","url":null,"abstract":"<p><p>The cloud network is rapidly growing due to a massive increase in interconnected devices and the emergence of different technologies such as the Internet of things, fog computing, and artificial intelligence. In response, cloud computing needs reliable dealings among the service providers, brokers, and consumers. The existing cloud monitoring frameworks such as Amazon Cloud Watch, Paraleap Azure Watch, and Rack Space Cloud Kick work under the control of service providers. They work fine; however, this may create dissatisfaction among customers over Service Level Agreement (SLA) violations. Customers' dissatisfaction may drastically reduce the businesses of service providers. To cope with the earlier mentioned issue and get in line with cloud philosophy, Monitoring as a Service (MaaS), completely independent in nature, is needed for observing and regulating the cloud businesses. However, the existing MaaS frameworks do not address the comprehensive SLA for customer satisfaction and penalties management. This article proposes a reliable framework for monitoring the provider's services by adopting third-party monitoring services with clearcut SLA and penalties management. Since this framework monitors SLA as a cloud monitoring service, it is named as SLA-MaaS. On violations, it penalizes those who are found in breach of terms and condition enlisted in SLA. Simulation results confirmed that the proposed framework adequately satisfies the customers (as well as service providers). This helps in developing a trustworthy relationship among cloud partners and increases customer attention and retention.</p>","PeriodicalId":51314,"journal":{"name":"Big Data","volume":" ","pages":"339-354"},"PeriodicalIF":4.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39857084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01Epub Date: 2023-01-19DOI: 10.1089/big.2021.0333
Guowei Zhang, Weilan Wang, Ce Zhang, Penghai Zhao, Mingkai Zhang
Recognition of handwritten Uchen Tibetan characters input has been considered an efficient way of acquiring mass data in the digital era. However, it still faces considerable challenges due to seriously touching letters and various morphological features of identical characters. Thus, deeper neural networks are required to achieve decent recognition accuracy, making an efficient, lightweight model design important to balance the inevitable trade-off between accuracy and latency. To reduce the learnable parameters of the network as much as possible and maintain acceptable accuracy, we introduce an efficient model named HUTNet based on the internal relationship between floating-point operations per second (FLOPs) and Memory Access Cost. The proposed network achieves a ResNet-18-level accuracy of 96.86%, with only a tenth of the parameters. The subsequent pruning and knowledge distillation strategies were applied to further reduce the inference latency of the model. Experiments on the test set (Handwritten Uchen Tibetan Data set by Wang [HUTDW]) containing 562 classes of 42,068 samples show that the compressed model achieves a 96.83% accuracy while maintaining lower FLOPs and fewer parameters. To verify the effectiveness of HUTNet, we tested it on the Chinese Handwriting Data sets Handwriting Database 1.1 (HWDB1.1), in which HUTNet achieved an accuracy of 97.24%, higher than that of ResNet-18 and ResNet-34. In general, we conduct extensive experiments on resource and accuracy trade-offs and show a stronger performance compared with other famous models on HUTDW and HWDB1.1. It also unlocks the critical bottleneck for handwritten Uchen Tibetan recognition on low-power computing devices.
{"title":"HUTNet: An Efficient Convolutional Neural Network for Handwritten Uchen Tibetan Character Recognition.","authors":"Guowei Zhang, Weilan Wang, Ce Zhang, Penghai Zhao, Mingkai Zhang","doi":"10.1089/big.2021.0333","DOIUrl":"10.1089/big.2021.0333","url":null,"abstract":"<p><p>Recognition of handwritten Uchen Tibetan characters input has been considered an efficient way of acquiring mass data in the digital era. However, it still faces considerable challenges due to seriously touching letters and various morphological features of identical characters. Thus, deeper neural networks are required to achieve decent recognition accuracy, making an efficient, lightweight model design important to balance the inevitable trade-off between accuracy and latency. To reduce the learnable parameters of the network as much as possible and maintain acceptable accuracy, we introduce an efficient model named HUTNet based on the internal relationship between floating-point operations per second (FLOPs) and Memory Access Cost. The proposed network achieves a ResNet-18-level accuracy of 96.86%, with only a tenth of the parameters. The subsequent pruning and knowledge distillation strategies were applied to further reduce the inference latency of the model. Experiments on the test set (Handwritten Uchen Tibetan Data set by Wang [HUTDW]) containing 562 classes of 42,068 samples show that the compressed model achieves a 96.83% accuracy while maintaining lower FLOPs and fewer parameters. To verify the effectiveness of HUTNet, we tested it on the Chinese Handwriting Data sets Handwriting Database 1.1 (HWDB1.1), in which HUTNet achieved an accuracy of 97.24%, higher than that of ResNet-18 and ResNet-34. In general, we conduct extensive experiments on resource and accuracy trade-offs and show a stronger performance compared with other famous models on HUTDW and HWDB1.1. It also unlocks the critical bottleneck for handwritten Uchen Tibetan recognition on low-power computing devices.</p>","PeriodicalId":51314,"journal":{"name":"Big Data","volume":" ","pages":"387-398"},"PeriodicalIF":4.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10543391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}