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Exercise snacks improve cognitive function and alleviate anxiety, depression, and stress in adolescents with childhood trauma 运动零食改善认知功能和减轻焦虑,抑郁和压力的青少年与童年创伤
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-18 DOI: 10.1016/j.mhpa.2025.100745
Benke Xu, Mingqi Wang, Guangyi Liu, Guoxiao Sun

Objective

This study aimed to investigate the effects of the 6-week exercise snacks (ES) intervention on anxiety, depression, stress, and cognitive function in adolescents with childhood trauma (CT), and to explore its underlying neural mechanisms.

Methods

A randomized controlled trial was conducted, enrolling 43 CT-screened adolescents (15–18 years) allocated to an ES group (n = 22) or a control group (n = 21). The ES group completed a 6-week high-intensity interval program (three 30-s bursts of exercise, thrice daily on three non-consecutive weekly days), while controls maintained routine activities. Cognitive performance was assessed via the Stroop task, while emotional states were evaluated using the Children's Depression Inventory (CDI), Chinese Perceived Stress Scale (CPSS), and Screen for Child Anxiety Related Emotional Disorders (SCARED). Activation of the prefrontal cortex was monitored using fNIRS.

Results

Linear mixed models revealed significant improvements in congruent-task RT (β = −0.727, p = 0.001), incongruent-task RT (β = −1.247, p < 0.001), congruent-task EFS (β = 0.664, p = 0.007), and incongruent-task EFS (β = 0.676, p = 0.048) in the ES group. Reductions in SCARED, CPSS, and CDI scores were also observed. Neuroimaging demonstrated enhanced activation in the L-DLPFC during congruent (β = 0.862, p = 0.008) and incongruent-tasks (β = 0.960, p = 0.003) in the ES group, whereas controls exhibited increased R-OFC activation (congruent: β = −0.785, p = 0.021; incongruent: β = −0.894, p = 0.017)

Conclusions

The 6-week exercise snacks intervention significantly improved cognitive function and alleviated negative emotions in adolescents with childhood trauma. The improvement in cognitive function was associated with enhanced activation in the L-DLPFC and a suppression of aberrant activation in the R-OFC.
目的研究运动零食(ES)干预6周后对儿童创伤青少年焦虑、抑郁、应激和认知功能的影响,并探讨其潜在的神经机制。方法采用随机对照试验方法,将43例15 ~ 18岁的ct筛查青少年分为ES组(n = 22)和对照组(n = 21)。ES组完成了为期6周的高强度间歇训练(3次30秒的间歇锻炼,每天3次,每周3次,不连续),而对照组则保持常规活动。通过Stroop任务评估认知表现,使用儿童抑郁量表(CDI)、中国感知压力量表(CPSS)和儿童焦虑相关情绪障碍筛查(SCARED)评估情绪状态。使用近红外光谱监测前额皮质的激活。结果线性混合模型显示,ES组在一致性任务RT (β = - 0.727, p = 0.001)、不一致性任务RT (β = - 1.247, p < 0.001)、一致性任务EFS (β = 0.664, p = 0.007)和不一致性任务EFS (β = 0.676, p = 0.048)方面均有显著改善。还观察到SCARED、CPSS和CDI评分的降低。神经影像学显示,在一致性任务(β = 0.862, p = 0.008)和不一致性任务(β = 0.960, p = 0.003)中,ES组的L-DLPFC激活增强,而对照组的R-OFC激活增强(一致性任务:β = - 0.785, p = 0.021;不一致性任务:β = - 0.894, p = 0.017)。结论:6周运动零食干预可显著改善儿童创伤青少年的认知功能,缓解负性情绪。认知功能的改善与L-DLPFC激活的增强和R-OFC异常激活的抑制有关。
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引用次数: 0
Association of moderate to vigorous physical activity with cognitive performance and risk of cognitive impairment: A cross-sectional study and Mendelian randomization analysis 中高强度体力活动与认知能力和认知障碍风险的关联:横断面研究和孟德尔随机化分析
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-15 DOI: 10.1016/j.mhpa.2025.100744
Qifeng Han , Sung Min Kim

Background

Cognitive performance and cognitive impairment are critical indicators of brain health in older adults, with moderate-to-vigorous physical activity (MVPA) suggested as protective, though its causal relationship remains unclear.

Methods

Using data from the National Health and Nutrition Examination Survey (NHANES), weighted linear and logistic regression assessed associations between MVPA, cognitive performance, and cognitive impairment risk. Restricted cubic spline and subgroup analyses examined dose–response and robustness. Additionally, genome-wide association study (GWAS) data were used for two-sample Mendelian randomization to explore causality.

Results

Cross-sectional analysis showed that moderate MVPA was associated with better cognitive performance (β = 0.35, p = 0.015) and exhibited a nonlinear trend. High levels of MVPA were significantly associated with a reduced risk of cognitive impairment (OR = 0.44, p = 0.009). Subgroup analysis indicated consistent associations between physical activity and cognitive outcomes across different populations without significant interactions. The MR analysis demonstrated a negative effect of MVPA on cognitive performance (β = −0.54, p < 0.001). However, no significant causal relationship was found between MVPA and the risk of cognitive impairment.

Conclusion

MVPA was associated with better cognitive performance and a lower risk of cognitive impairment in cross-sectional analyses, but MR findings did not support a protective causal effect and indicated a potential negative association with cognitive performance. These mixed results suggest that the causal impact of MVPA on cognitive health in later life remains uncertain, and that the potential benefits and optimal dose of MVPA should be clarified in future large-scale longitudinal and intervention studies using objective and age appropriate assessments of activity.
认知表现和认知障碍是老年人大脑健康的重要指标,中度至剧烈的体育活动(MVPA)被认为具有保护作用,尽管其因果关系尚不清楚。方法使用国家健康与营养调查(NHANES)的数据,加权线性和逻辑回归评估MVPA、认知表现和认知功能障碍风险之间的关系。限制性三次样条和亚组分析检验了剂量-反应和稳健性。此外,全基因组关联研究(GWAS)数据被用于两样本孟德尔随机化来探索因果关系。结果横截面分析显示,中度MVPA与较好的认知能力相关(β = 0.35, p = 0.015),且呈非线性趋势。高水平的MVPA与认知障碍风险降低显著相关(OR = 0.44, p = 0.009)。亚组分析表明,在不同人群中,身体活动与认知结果之间存在一致的关联,但没有显著的相互作用。磁共振分析显示MVPA对认知表现有负面影响(β = - 0.54, p < 0.001)。然而,MVPA与认知障碍风险之间没有明显的因果关系。结论在横断面分析中,mvpa与更好的认知表现和更低的认知障碍风险相关,但MR研究结果不支持保护性因果效应,并表明mvpa与认知表现存在潜在的负相关。这些混杂的结果表明,MVPA对晚年认知健康的因果影响仍不确定,MVPA的潜在益处和最佳剂量应在未来的大规模纵向和干预研究中得到澄清,这些研究使用客观和适合年龄的活动评估。
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引用次数: 0
Maternal well-being for working mothers in the U.S. who participate in Peloton™ exercise 参与Peloton™运动的美国职业母亲的健康状况
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-11-29 DOI: 10.1016/j.mhpa.2025.100743
Bethany Fleck Dillen , Michael Rhoads , Isabel Kool

Statement of purpose

This study addresses the mental and physical well-being of working mothers from the United States who used Peloton™ during the COVID-19 pandemic. The objective is to investigate the relationship between exercise behavior and maternal well-being, focusing on parenting stress, parental self-efficacy, and guilt. Research questions explore whether Peloton use moderates these factors.

Method

This study involved 144 working mothers whose children's ages ranged from birth to 18. Mothers participated in an online survey.

Results

Parenting stress was linked to lower quality of life, self-efficacy, and happiness, and higher shame. High-intensity Peloton use related positively to psychological and social quality of life, but negatively to self-efficacy.

Conclusions

Encouraging regular physical activity may support maternal well-being, especially under high stress. Online platforms like Peloton offer accessible options for busy mothers.
本研究针对在COVID-19大流行期间使用Peloton™的美国职业母亲的身心健康状况。目的是调查运动行为和母亲幸福感之间的关系,重点关注养育压力、父母自我效能和内疚。研究问题探讨Peloton使用是否会调节这些因素。方法本研究涉及144名职业母亲,她们的孩子年龄从出生到18岁不等。母亲们参与了一项在线调查。结果养育压力与生活质量、自我效能、幸福感和羞耻感降低有关。高强度Peloton使用与心理和社会生活质量呈正相关,但与自我效能负相关。结论鼓励有规律的体育活动可能有助于产妇健康,特别是在高压力下。Peloton等在线平台为忙碌的妈妈们提供了方便的选择。
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引用次数: 0
Barriers and facilitators of evidence-based exercise therapy as adjunct treatment for major depressive disorder in specialized mental health care 循证运动疗法在专业精神卫生保健中作为重度抑郁症辅助治疗的障碍和促进因素
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-11-29 DOI: 10.1016/j.mhpa.2025.100742
Laura Shields-Zeeman , Michele Schmitter , Joelle Vilé , Annelot van Geffen , Tessa van Doesum , Ben Wijnen , Peter Oostelbos , Jasper A.J. Smits , Jan Spijker , Janna N. Vrijsen

Purpose

Major Depressive Disorder (MDD) is a pervasive public health challenge, and although exercise therapy shows promise as an adjunct treatment, its integration into routine mental health care remains limited. This study examines the barriers and facilitators to implementing evidence-based exercise therapy for MDD in Dutch specialized mental health care settings.

Methods

We explored implementation processes alongside the Exercise Enhances randomized controlled trial. Data were collected through semi-structured interviews with patients (N = 6) and with professionals through focus group discussions (N = 8) and a questionnaire exploring barriers and facilitators to implementation (N = 12).

Results

Results indicate that both patients and professionals perceive exercise therapy as beneficial for mood and overall well-being. Key facilitators include the intervention's adaptability, its alignment with existing clinical routines, and the patient-centered support provided by exercise therapists. However, barriers included limited exercise modalities, challenges in adherence to home-based sessions, interprofessional communication gaps, and insufficient organizational resources.

Conclusions

While integrating exercise as an adjunct treatment for MDD is feasible and well received, sustained implementation requires enhanced flexibility in program design, improved interdisciplinary collaboration, and dedicated implementation coordination. These insights contribute to the evidence base for scaling exercise interventions within specialized mental health care and underscore the need for structural adjustments and targeted funding.
目的重度抑郁症(MDD)是一个普遍存在的公共卫生挑战,尽管运动疗法作为一种辅助治疗显示出希望,但它与常规精神卫生保健的结合仍然有限。本研究考察了在荷兰专业精神卫生保健机构实施循证运动疗法治疗重度抑郁症的障碍和促进因素。方法:我们在锻炼增强随机对照试验的同时探索实施过程。通过与患者(N = 6)进行半结构化访谈,通过焦点小组讨论(N = 8)与专业人员(N = 12)进行问卷调查,探讨实施障碍和促进因素,收集数据。结果表明,患者和专业人士都认为运动疗法对情绪和整体健康有益。关键的促进因素包括干预的适应性,与现有临床常规的一致性,以及运动治疗师提供的以患者为中心的支持。然而,障碍包括有限的锻炼方式、坚持以家庭为基础的会议的挑战、专业间的沟通差距和组织资源不足。结论:虽然将锻炼作为MDD的辅助治疗方法是可行的,并且很受欢迎,但持续实施需要增强方案设计的灵活性,改善跨学科合作,以及专门的实施协调。这些见解有助于在专业精神卫生保健中扩大运动干预的证据基础,并强调了结构调整和有针对性的资金的必要性。
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引用次数: 0
Effectiveness of a non-conventional physical activity intervention on lifestyle indicators in adults with depressive symptoms: a randomized clinical trial 非常规体育活动干预对成人抑郁症状生活方式指标的有效性:一项随机临床试验
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-11-24 DOI: 10.1016/j.mhpa.2025.100732
Samara Mendes de Sousa, Cecília Bertuol, Edú Fiorin Schopf, Luciene Rafaela Franco dos Santos, Josefina Bertoli, Giovani Firpo Del Duca

Background

Adults with depressive symptoms often exhibit health-risk behaviors, including physical inactivity, poor diet, alcohol consumption, and poor sleep Thus, the aim of this study was to evaluate the effectiveness of a physical activity intervention on lifestyle indicators in adults with depressive symptoms.

Methods

Adults aged 20–59 years with depressive symptoms were randomly assigned to an intervention group (IG; n = 39) or control group (CG; n = 39). The 16-week intervention combined diverse physical activities with psychoeducational sessions based on Self-Determination Theory. Lifestyle was assessed using the Fantastic Lifestyle Questionnaire, applied pre- and post-intervention. Generalized Estimating Equations (GEE) were used for both per-protocol (PP) and intention-to-treat (ITT) analyses.

Results

Among the 78 participants (76.9 % women; mean age 38.27 ± 10.46 years), the PP analysis showed significant group∗time interaction effects for the total lifestyle score (p = 0.026), as well as for the indicators of sleep quality, seatbelt use, stress management, safe sex (p < 0.001), and introspection (p = 0.027), favoring the IG over time and when compared to the CG at post-intervention. The ITT analysis revealed positive group∗time interactions for sleep, seatbelt use, stress, and safe sex (p = 0.009), with improvements observed in both groups over time. Additionally, improvements in behavior type were found only in the IG (p = 0.069). However, a worsening was detected in the alcohol-related domain (p = 0.037) for the IG over time.

Conclusion

The intervention demonstrated promising but mixed effects on lifestyle outcomes among adults with depressive symptoms.
背景:患有抑郁症状的成年人经常表现出危害健康的行为,包括缺乏身体活动、不良饮食、饮酒和睡眠不足,因此,本研究的目的是评估身体活动干预对患有抑郁症状的成年人生活方式指标的有效性。方法20 ~ 59岁有抑郁症状的成年人随机分为干预组(IG, n = 39)和对照组(CG, n = 39)。为期16周的干预结合了多种体育活动和基于自我决定理论的心理教育课程。生活方式采用奇妙生活方式问卷进行评估,应用于干预前后。广义估计方程(GEE)被用于每个方案(PP)和意向治疗(ITT)分析。结果在78名参与者中(76.9%为女性,平均年龄38.27±10.46岁),PP分析显示,在总生活方式评分(p = 0.026),以及睡眠质量、安全带使用、压力管理、安全性行为(p < 0.001)和自省(p = 0.027)等指标上,与干预后的CG相比,IG随着时间的推移更倾向于IG。ITT分析显示,两组在睡眠、安全带使用、压力和安全性行为方面的交互作用(p = 0.009)为正(p = 0.009),随着时间的推移,两组均有改善。此外,行为类型的改善仅在IG中发现(p = 0.069)。然而,随着时间的推移,IG的酒精相关区域出现恶化(p = 0.037)。结论干预对成人抑郁症状生活方式结局的影响有希望,但效果不一。
{"title":"Effectiveness of a non-conventional physical activity intervention on lifestyle indicators in adults with depressive symptoms: a randomized clinical trial","authors":"Samara Mendes de Sousa,&nbsp;Cecília Bertuol,&nbsp;Edú Fiorin Schopf,&nbsp;Luciene Rafaela Franco dos Santos,&nbsp;Josefina Bertoli,&nbsp;Giovani Firpo Del Duca","doi":"10.1016/j.mhpa.2025.100732","DOIUrl":"10.1016/j.mhpa.2025.100732","url":null,"abstract":"<div><h3>Background</h3><div>Adults with depressive symptoms often exhibit health-risk behaviors, including physical inactivity, poor diet, alcohol consumption, and poor sleep Thus, the aim of this study was to evaluate the effectiveness of a physical activity intervention on lifestyle indicators in adults with depressive symptoms.</div></div><div><h3>Methods</h3><div>Adults aged 20–59 years with depressive symptoms were randomly assigned to an intervention group (IG; n = 39) or control group (CG; n = 39). The 16-week intervention combined diverse physical activities with psychoeducational sessions based on Self-Determination Theory. Lifestyle was assessed using the Fantastic Lifestyle Questionnaire, applied pre- and post-intervention. Generalized Estimating Equations (GEE) were used for both per-protocol (PP) and intention-to-treat (ITT) analyses.</div></div><div><h3>Results</h3><div>Among the 78 participants (76.9 % women; mean age 38.27 ± 10.46 years), the PP analysis showed significant group∗time interaction effects for the total lifestyle score (p = 0.026), as well as for the indicators of sleep quality, seatbelt use, stress management, safe sex (p &lt; 0.001), and introspection (p = 0.027), favoring the IG over time and when compared to the CG at post-intervention. The ITT analysis revealed positive group∗time interactions for sleep, seatbelt use, stress, and safe sex (p = 0.009), with improvements observed in both groups over time. Additionally, improvements in behavior type were found only in the IG (p = 0.069). However, a worsening was detected in the alcohol-related domain (p = 0.037) for the IG over time.</div></div><div><h3>Conclusion</h3><div>The intervention demonstrated promising but mixed effects on lifestyle outcomes among adults with depressive symptoms.</div></div>","PeriodicalId":51589,"journal":{"name":"Mental Health and Physical Activity","volume":"30 ","pages":"Article 100732"},"PeriodicalIF":2.6,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screen use, physical activity, and sleep among adolescents: A latent class analysis of 4,421 Danish adolescents’ movement patterns and the correlation with mental health 青少年的屏幕使用、身体活动和睡眠:对4,421名丹麦青少年的运动模式及其与心理健康的相关性进行潜在分类分析
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-28 DOI: 10.1016/j.mhpa.2025.100726
Mette Nygaard , Susan Andersen , Mette Toftager , Mette Rasmussen , Katrine Rich Madsen , Christina Bjørk Petersen

Background and aims

Screen use, physical activity, and sleep independently impact adolescents’ mental health, yet further exploration is needed to understand its dynamic impact. This study aimed to examine how movement behaviour cluster in Danish adolescents and how these movement patterns correlate with mental health.

Methods

Data were collected among Danish adolescents as part of the cross-sectional Health Behaviour in School-Aged Children (HBSC) study in 2018 and 2022. Study population comprised 4421 adolescents (51.5 % girls, age 11, 13 and 15). Latent class analysis was performed separately for boys and girls based on self-reported screen time (5 items), physical activity level (2 items), and sleep duration (1 item). Associations between classes and mental health (mental wellbeing, psychosomatic complaints, and body image) were evaluated using adjusted regression models stratified on sex.

Results

Three movement patterns were identified. Class 1 represented medium screen users with high physical activity (34.3 % of boys; 28.1 % of girls); class 2 represented medium screen users with low physical activity (41.8 %; 42.5 %); and class 3 represented high screen users with short sleep duration (23.8 %; 29.3 %). Compared to class 1, adolescents in class 2 and 3 reported substantially poorer mental wellbeing, more psychosomatic complaints, and poorer body image, especially girls in class 3.

Conclusion

Screen use, sleep, and physical activity behaviour tend to group in three movement patterns among Danish adolescents. The identified patterns were associated with notable differences in mental health outcomes. Results emphasize the benefits of high physical activity, low screen time and sufficient sleep, supporting interventions targeting multiple movement behaviours at once.
背景和目的屏幕使用、身体活动和睡眠独立影响青少年心理健康,但需要进一步探索其动态影响。本研究旨在研究丹麦青少年的运动行为如何聚集,以及这些运动模式如何与心理健康相关。方法收集丹麦青少年的数据,作为2018年和2022年学龄儿童横断面健康行为(HBSC)研究的一部分。研究人群包括4421名青少年(51.5%为女孩,11、13和15岁)。基于自我报告的屏幕时间(5项)、身体活动水平(2项)和睡眠时间(1项),对男孩和女孩分别进行潜在类别分析。班级与心理健康(心理健康、心身疾患和身体形象)之间的关系使用调整后的回归模型按性别分层进行评估。结果鉴定出三种运动模式。第一类是高体力活动的中等屏幕使用者(34.3%的男孩和28.1%的女孩);第2类为低体力活动的中等屏幕使用者(41.8%;42.5%);第3类代表高屏幕用户,睡眠时间短(23.8%;29.3%)。与1班相比,2班和3班的青少年心理健康状况明显较差,身心疾病较多,身体形象较差,尤其是3班的女孩。结论丹麦青少年的屏幕使用、睡眠和身体活动行为倾向于三种运动模式。确定的模式与心理健康结果的显着差异有关。研究结果强调了高体力活动、低屏幕时间和充足睡眠的好处,支持了针对多种运动行为的干预措施。
{"title":"Screen use, physical activity, and sleep among adolescents: A latent class analysis of 4,421 Danish adolescents’ movement patterns and the correlation with mental health","authors":"Mette Nygaard ,&nbsp;Susan Andersen ,&nbsp;Mette Toftager ,&nbsp;Mette Rasmussen ,&nbsp;Katrine Rich Madsen ,&nbsp;Christina Bjørk Petersen","doi":"10.1016/j.mhpa.2025.100726","DOIUrl":"10.1016/j.mhpa.2025.100726","url":null,"abstract":"<div><h3>Background and aims</h3><div>Screen use, physical activity, and sleep independently impact adolescents’ mental health, yet further exploration is needed to understand its dynamic impact. This study aimed to examine how movement behaviour cluster in Danish adolescents and how these movement patterns correlate with mental health.</div></div><div><h3>Methods</h3><div>Data were collected among Danish adolescents as part of the cross-sectional Health Behaviour in School-Aged Children (HBSC) study in 2018 and 2022. Study population comprised 4421 adolescents (51.5 % girls, age 11, 13 and 15). Latent class analysis was performed separately for boys and girls based on self-reported screen time (5 items), physical activity level (2 items), and sleep duration (1 item). Associations between classes and mental health (mental wellbeing, psychosomatic complaints, and body image) were evaluated using adjusted regression models stratified on sex.</div></div><div><h3>Results</h3><div>Three movement patterns were identified. Class 1 represented medium screen users with high physical activity (34.3 % of boys; 28.1 % of girls); class 2 represented medium screen users with low physical activity (41.8 %; 42.5 %); and class 3 represented high screen users with short sleep duration (23.8 %; 29.3 %). Compared to class 1, adolescents in class 2 and 3 reported substantially poorer mental wellbeing, more psychosomatic complaints, and poorer body image, especially girls in class 3.</div></div><div><h3>Conclusion</h3><div>Screen use, sleep, and physical activity behaviour tend to group in three movement patterns among Danish adolescents. The identified patterns were associated with notable differences in mental health outcomes. Results emphasize the benefits of high physical activity, low screen time and sufficient sleep, supporting interventions targeting multiple movement behaviours at once.</div></div>","PeriodicalId":51589,"journal":{"name":"Mental Health and Physical Activity","volume":"30 ","pages":"Article 100726"},"PeriodicalIF":2.6,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145600406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility and effects of high-intensity interval training for improving depressive symptoms in older adults: a systematic review and meta-analysis of randomized controlled studies 高强度间歇训练改善老年人抑郁症状的可行性和效果:随机对照研究的系统回顾和荟萃分析
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 DOI: 10.1016/j.mhpa.2025.100731
Yanping Wang , Yanping Duan , Dehiwala Liyanage Ishanka Harshani Kusum Peiris , Wei Liang

Background

High-intensity interval training (HIIT) is an emerging and cost-effective exercise to reduce depressive symptoms. However, there is a lack of overview of HIIT for depressive symptoms among older adults. The objective of this study was to synthesise the feasibility and effects of HIIT on depressive symptoms among older adults.

Methods

This study followed the PRISMA guideline. Eight electronic databases (PubMed, EMBASE, Medline, PsycINFO, SPORTDiscus, Web of Science, Scopus, and Cochrane Central Register of Controlled Trials (CENTRAL)) were searched to screen eligible studies. Cochrane's risk of bias tool and GRADE approaches were used to evaluate the methodology and evidence quality. Random effects meta-analyses were performed for adverse events and depressive symptoms. Sub-group meta-analyses were performed on depressive symptoms based on characteristics of participants and the HIIT protocol.

Results

A total of 18 studies were identified in the systematic review. The retention and attendance rates of the HIIT group ranged from 59 % to 100 % and 74 % to 97 %, respectively. No significant differences were found in adverse events between HIIT and other exercises (RR = 1.34 [95 % CI 0.92, 1.95]; p = 0.13; I2 = 0 %; n = 5). Depressive symptoms were significantly reduced immediately after HIIT (SMD = −0.19 [95 % CI -0.36, −0.02]; p = 0.03; I2 = 47 %; n = 17). HIIT had a similar effect on depressive symptoms compared to other exercises (SMD = 0.06 [95 % CI -0.08, 0.20]; p = 0.41; I2 = 0 %; n = 13) and non-exercise control groups (SMD = −0.08 [95 % CI -0.43, 0.27]; p = 0.64; I2 = 75 %; n = 9).

Conclusion

HIIT demonstrated feasible attendance and retention, as well as a similar possibility of adverse events to conventional exercises among older adults. Depressive symptoms were reduced immediately after HIIT, while there was no superiority over other control groups among older adults. Future studies with high-quality evidence are needed to examine the effect of HIIT for improving depressive symptoms among older adults.

Prospero registration number

CRD42023443913.
背景:高强度间歇训练(HIIT)是一种新兴的、具有成本效益的减轻抑郁症状的运动。然而,缺乏HIIT治疗老年人抑郁症状的概述。本研究的目的是综合HIIT治疗老年人抑郁症状的可行性和效果。方法本研究遵循PRISMA指南。检索了8个电子数据库(PubMed, EMBASE, Medline, PsycINFO, SPORTDiscus, Web of Science, Scopus和Cochrane Central Register of Controlled Trials (Central))以筛选符合条件的研究。使用Cochrane的偏倚风险工具和GRADE方法来评估方法和证据质量。对不良事件和抑郁症状进行随机效应荟萃分析。根据参与者的特征和HIIT方案对抑郁症状进行亚组荟萃分析。结果系统评价共纳入18项研究。HIIT组的保留率和出勤率分别从59%到100%和74%到97%不等。HIIT与其他运动的不良事件发生率无显著差异(RR = 1.34 [95% CI 0.92, 1.95]; p = 0.13; I2 = 0%; n = 5)。HIIT后抑郁症状立即显著减轻(SMD = - 0.19 [95% CI -0.36, - 0.02]; p = 0.03; I2 = 47%; n = 17)。与其他运动组(SMD = 0.06 [95% CI -0.08, 0.20]; p = 0.41; I2 = 0%; n = 13)和非运动对照组(SMD = -0.08 [95% CI -0.43, 0.27]; p = 0.64; I2 = 75%; n = 9)相比,HIIT对抑郁症状的影响相似。结论:在老年人中,hiit的参加和保持是可行的,并且不良事件的可能性与传统运动相似。HIIT后抑郁症状立即减轻,而在老年人中没有优于其他对照组的优势。未来需要有高质量证据的研究来检验HIIT对改善老年人抑郁症状的影响。普洛斯彼罗注册号crd42023443913。
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引用次数: 0
The timing or accumulation of physical activity during adolescence: which better predicts positive mental health and quality of life in early adulthood? 青春期体育活动的时间或积累:哪个能更好地预测成年早期积极的心理健康和生活质量?
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 DOI: 10.1016/j.mhpa.2025.100727
Pierre Philippe Wilson Registe , Salma Jemaa , Saïd Mekari , Marie-Pierre Sylvestre , Magaly Brodeur , Mathieu Bélanger

Background

While adolescent physical activity (PA) is thought to positively impact future mental health and quality of life (QoL), no research has assessed whether the timing of exposure to PA in adolescence matters. This study aims to investigate whether total exposure to PA, or PA at specific periods during adolescence, is more strongly associated with these two health outcomes in early adulthood.

Methods

We used data from the MATCH longitudinal study, conducted from 2011 to 2024, which included eight years of PA measurement during adolescence and four yearly measures of positive mental health and QoL during early adulthood. Adolescent PA history was summarized with a Cumulative Index of Exposure (CIE) to represent total adolescent PA and with a Weighted Cumulative Exposure (WCE) approach to differentiate PA accumulated at each age. PA history variables were incorporated into linear mixed models to assess their associations with positive mental health (n = 536) and QoL (n = 541).

Results

During the four years of early adulthood, positive mental health declined slightly, while QoL remained stable. Total PA during adolescence (CIE) was positively associated with the initial level of positive mental health (β=0.29; 95% CI: 0.19 to 0.40) and QoL (0.37; 0.24 to 0.51) in early adulthood. The WCE further showed that it is PA in later adolescence that is most strongly associated with better health outcomes in early adulthood.

Conclusions

The volume of PA accumulated during adolescence, particularly in late adolescence, is predictive of young adults’ positive mental health and QoL.
虽然青少年体育活动(PA)被认为对未来的心理健康和生活质量(QoL)有积极影响,但没有研究评估青少年接触体育活动的时间是否重要。这项研究的目的是调查是否总暴露于PA,或在青春期的特定时期暴露于PA,与成年早期的这两种健康结果更密切相关。方法:我们使用了2011年至2024年进行的MATCH纵向研究的数据,其中包括青春期8年的PA测量和成年早期4年的积极心理健康和生活质量测量。用累积暴露指数(CIE)和加权累积暴露(WCE)方法来区分每个年龄段累积的PA,总结青少年PA史。将PA病史变量纳入线性混合模型,以评估其与积极心理健康(n = 536)和生活质量(n = 541)的关系。结果在成年早期4年,积极心理健康略有下降,而生活质量保持稳定。青春期总PA (CIE)与成年早期的积极心理健康初始水平(β=0.29; 95% CI: 0.19 ~ 0.40)和生活质量(0.37;0.24 ~ 0.51)呈正相关。WCE进一步表明,青春期后期的PA与成年早期更好的健康结果最密切相关。结论青春期尤其是青春期后期PA积累量可预测青少年心理健康状况和生活质量。
{"title":"The timing or accumulation of physical activity during adolescence: which better predicts positive mental health and quality of life in early adulthood?","authors":"Pierre Philippe Wilson Registe ,&nbsp;Salma Jemaa ,&nbsp;Saïd Mekari ,&nbsp;Marie-Pierre Sylvestre ,&nbsp;Magaly Brodeur ,&nbsp;Mathieu Bélanger","doi":"10.1016/j.mhpa.2025.100727","DOIUrl":"10.1016/j.mhpa.2025.100727","url":null,"abstract":"<div><h3>Background</h3><div>While adolescent physical activity (PA) is thought to positively impact future mental health and quality of life (QoL), no research has assessed whether the timing of exposure to PA in adolescence matters. This study aims to investigate whether total exposure to PA, or PA at specific periods during adolescence, is more strongly associated with these two health outcomes in early adulthood.</div></div><div><h3>Methods</h3><div>We used data from the MATCH longitudinal study, conducted from 2011 to 2024, which included eight years of PA measurement during adolescence and four yearly measures of positive mental health and QoL during early adulthood. Adolescent PA history was summarized with a Cumulative Index of Exposure (CIE) to represent total adolescent PA and with a Weighted Cumulative Exposure (WCE) approach to differentiate PA accumulated at each age. PA history variables were incorporated into linear mixed models to assess their associations with positive mental health (<em>n</em> = 536) and QoL (<em>n</em> = 541).</div></div><div><h3>Results</h3><div>During the four years of early adulthood, positive mental health declined slightly, while QoL remained stable. Total PA during adolescence (CIE) was positively associated with the initial level of positive mental health (β=0.29; 95% CI: 0.19 to 0.40) and QoL (0.37; 0.24 to 0.51) in early adulthood. The WCE further showed that it is PA in later adolescence that is most strongly associated with better health outcomes in early adulthood.</div></div><div><h3>Conclusions</h3><div>The volume of PA accumulated during adolescence, particularly in late adolescence, is predictive of young adults’ positive mental health and QoL.</div></div>","PeriodicalId":51589,"journal":{"name":"Mental Health and Physical Activity","volume":"29 ","pages":"Article 100727"},"PeriodicalIF":2.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the long-term sustainability of lifestyle therapy for reducing depressive symptoms: A mixed methods study of the Curbing Anxiety and depression using Lifestyle Medicine (CALM) non-inferiority trial at 9-month follow-up 探索生活方式治疗减轻抑郁症状的长期可持续性:一项使用生活方式药物抑制焦虑和抑郁(CALM)的混合方法研究,为期9个月的随访
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 DOI: 10.1016/j.mhpa.2025.100730
Megan Turner , Melissa O'Shea , Lily Thurston , Rachael Jinnette , Alexander Beaconsfield , Sophie Mahoney , Deborah N. Ashtree , Marita Bryan , Dean Saunders , Tayla John , Lauren M. Young , Megan Teychenne , Felice Jacka , Lara K. Radovic , Adrienne O'Neil

Background and aims

Lifestyle therapies targeting nutrition and exercise are emerging as effective treatments for a range of mental health conditions. However, less is known about their longer-term effects. The Curbing Anxiety and Depression Using Lifestyle Medicine (CALM) trial showed that remotely delivered lifestyle therapy (exercise and nutritional counselling with a dietitian and exercise physiologist) is as clinically and cost-effective as psychotherapy (with psychologists) of similar intensity and frequency for reducing depressive symptoms in Australian adults. We aimed to assess reductions in PHQ-9 (Patient Health Questionnaire-9) scores were maintained at 9-month follow-up (primary aim) and to identify which factors contribute to the maintenance of lifestyle therapy practices compared with psychotherapy (secondary aim).

Methods

A mixed methods design was used. For the primary aim, a generalized equation model fit PHQ-9 scores across baseline, 8-weeks, and 9-months. Analyses were run using intention-to-treat (ITT; N = 182), per protocol (PP; N = 135), and complete case (CC; N = 64). Verbatim responses to interview questions about barriers and facilitators of maintaining practices were analysed using a descriptive qualitative approach.

Results

Both treatment arms showed significant reductions in PHQ-9 scores between baseline and 9 months (CC: lifestyle therapy MD = −3.76, 95 %CI-5.71,-1.80; psychotherapy MD = −3.24, 95 %CI -4.63,-1.86). Non-inferiority was established for the PP and ITT samples. However, between arm differences were observed in the CC sample at 9-month follow-up, with the lifestyle arm showing higher scores than psychotherapy (β: 2.68; 95 %CI:0.84,4.52, p = 0.004). This possibly reflected the significantly lower baseline PHQ-9 scores in the psychotherapy CC sample, which was explored using post-hoc analysis. Facilitators for maintaining lifestyle practices included the ease of incorporating nutritional changes into everyday life. Barriers included physical and mental health challenges.

Conclusion

If replicated within a larger sample, these findings suggest that lifestyle therapy has comparable longer-term effects on depressive symptoms as psychotherapy.
背景和目的以营养和运动为目标的生活方式疗法正在成为一系列心理健康状况的有效治疗方法。然而,人们对它们的长期影响知之甚少。使用生活方式药物抑制焦虑和抑郁(CALM)试验表明,远程提供的生活方式治疗(由营养师和运动生理学家提供运动和营养咨询)与心理治疗(由心理学家提供)在临床上和成本效益上一样,在减少澳大利亚成年人的抑郁症状方面具有相似的强度和频率。我们的目的是评估PHQ-9(患者健康问卷-9)得分的降低在9个月的随访中保持(主要目的),并确定与心理治疗相比,哪些因素有助于维持生活方式治疗实践(次要目的)。方法采用混合方法设计。对于主要目的,一个广义方程模型拟合PHQ-9评分在基线,8周和9个月。采用意向治疗(ITT, N = 182)、每个方案(PP, N = 135)和完整病例(CC, N = 64)进行分析。使用描述性定性方法对有关维持实践的障碍和促进因素的访谈问题的逐字回答进行了分析。结果两个治疗组的PHQ-9评分在基线和9个月之间均有显著降低(CC:生活方式治疗MD = - 3.76, 95% CI-5.71,-1.80;心理治疗MD = - 3.24, 95% CI -4.63,-1.86)。对PP和ITT样本进行非劣效性检验。然而,在9个月的随访中,在CC样本中观察到两组之间的差异,生活方式组的得分高于心理治疗组(β: 2.68; 95% CI:0.84,4.52, p = 0.004)。这可能反映了心理治疗CC样本中显著较低的基线PHQ-9得分,这是用事后分析来探讨的。维持生活方式的促进因素包括将营养变化纳入日常生活的便利性。障碍包括身体和心理健康方面的挑战。结论:如果在更大的样本中重复,这些发现表明,生活方式疗法对抑郁症状的长期影响与心理治疗相当。
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引用次数: 0
Increasing activity and reducing sedentary behaviour for people with severe mental illness: what are the active ingredients for behaviour change? A systematic review 严重精神疾病患者增加活动和减少久坐行为:行为改变的有效因素是什么?系统回顾
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 DOI: 10.1016/j.mhpa.2025.100713
Gemma Traviss-Turner , Rebecca J. Beeken , Gareth Jones , Laura Bailey , Eleanor Bowes , Trys Burke , Katarzyna K. Machaczek , Katie Pickering , Robert Copeland , Cindy Cooper , Garry Tew , Scott Weich , Emily Peckham
Increasing physical activity (PA) and reducing sedentary behaviour (SB) can improve health outcomes and reduce rates of premature mortality for people with severe mental illness (SMI). In this systematic review we aimed to explore the active ingredients of existing PA interventions for people with SMI. We reviewed intervention functions, behaviour change techniques (BCTs), contextual features and underpinning theories. We included 15 PA interventions, of which 4 were classed as effective (effect size >0.273). We identified the frequency of intervention functions and BCTs that were used in each study and compared the number of effective studies that featured a particular BCT or intervention function with the total number that featured those components. We used the TIDieR checklist to document contextual features that might be important within effective interventions including the theories that guided the development of interventions. The most frequently used functions were education and environmental restructuring, both of which were identified in effective interventions. The BCTs that were identified as potentially useful were framing and reframing, feedback on behaviour and self-monitoring. No discernible contextual features were unique to the effective interventions, but combinations of some features seemed to be (PA tracking, educational components and support delivered by community health teams). More high quality and better reported studies are required to strengthen this evidence base.

Prospero registration

PROSPERO 2024 CRD42024541859
增加身体活动(PA)和减少久坐行为(SB)可以改善严重精神疾病(SMI)患者的健康结果并降低过早死亡率。在这篇系统综述中,我们旨在探讨重度精神分裂症患者现有PA干预措施的有效成分。我们回顾了干预功能,行为改变技术(bct),背景特征和基础理论。我们纳入了15项PA干预措施,其中4项被归类为有效(效应量>;0.273)。我们确定了每项研究中使用的干预功能和BCT的频率,并将具有特定BCT或干预功能的有效研究的数量与具有这些成分的总数进行了比较。我们使用TIDieR检查表来记录在有效干预措施中可能很重要的上下文特征,包括指导干预措施发展的理论。最常使用的职能是教育和环境改革,有效的干预措施确定了这两个职能。被确定为潜在有用的bct是框架和重构,行为反馈和自我监控。有效的干预措施没有明显的背景特征,但一些特征的组合似乎是独特的(PA跟踪,教育成分和社区卫生团队提供的支持)。需要更多高质量和更好的研究报告来加强这一证据基础。普洛斯彼罗注册,普洛斯彼罗2024 CRD42024541859
{"title":"Increasing activity and reducing sedentary behaviour for people with severe mental illness: what are the active ingredients for behaviour change? A systematic review","authors":"Gemma Traviss-Turner ,&nbsp;Rebecca J. Beeken ,&nbsp;Gareth Jones ,&nbsp;Laura Bailey ,&nbsp;Eleanor Bowes ,&nbsp;Trys Burke ,&nbsp;Katarzyna K. Machaczek ,&nbsp;Katie Pickering ,&nbsp;Robert Copeland ,&nbsp;Cindy Cooper ,&nbsp;Garry Tew ,&nbsp;Scott Weich ,&nbsp;Emily Peckham","doi":"10.1016/j.mhpa.2025.100713","DOIUrl":"10.1016/j.mhpa.2025.100713","url":null,"abstract":"<div><div>Increasing physical activity (PA) and reducing sedentary behaviour (SB) can improve health outcomes and reduce rates of premature mortality for people with severe mental illness (SMI). In this systematic review we aimed to explore the active ingredients of existing PA interventions for people with SMI. We reviewed intervention functions, behaviour change techniques (BCTs), contextual features and underpinning theories. We included 15 PA interventions, of which 4 were classed as effective (effect size &gt;0.273). We identified the frequency of intervention functions and BCTs that were used in each study and compared the number of effective studies that featured a particular BCT or intervention function with the total number that featured those components. We used the TIDieR checklist to document contextual features that might be important within effective interventions including the theories that guided the development of interventions. The most frequently used functions were education and environmental restructuring, both of which were identified in effective interventions. The BCTs that were identified as potentially useful were framing and reframing, feedback on behaviour and self-monitoring. No discernible contextual features were unique to the effective interventions, but combinations of some features seemed to be (PA tracking, educational components and support delivered by community health teams). More high quality and better reported studies are required to strengthen this evidence base.</div></div><div><h3>Prospero registration</h3><div>PROSPERO 2024 CRD42024541859</div></div>","PeriodicalId":51589,"journal":{"name":"Mental Health and Physical Activity","volume":"29 ","pages":"Article 100713"},"PeriodicalIF":2.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145219092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Mental Health and Physical Activity
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