Pub Date : 2025-12-01Epub Date: 2025-11-12DOI: 10.1016/j.wpi.2025.102409
Tsewang Stanzin, Ruchi Sharma
The Indian automobile industry is experiencing a rapid technological transition, shaped by growing pressures for environmental sustainability. While scholarship has extensively examined the role of FDI in transferring clean technologies to developing economies, less attention has been paid to the evolving domestic innovation landscape and the contributions of new entrants. Addressing this gap, the present study employs patent-based analysis to map the trajectory of green and dirty technologies in India's automobile industry. Using international patent classification codes, co-occurrence network analysis, and revealed technological advantage indices, we track resident and non-resident patent filings, examine the portfolios of incumbents and startups, and explore technological linkages between clean, dirty, and grey innovations. Our results reveal a sustained increase in clean patenting activity, especially in electric vehicle technologies. However, internal combustion engine-related innovations continue to dominate due to path dependency and regulatory-driven grey innovation. Startups demonstrate high specialization in clean technologies, whereas incumbent firms retain diversified portfolios. By uncovering the heterogeneous roles of incumbents and startups and highlighting the coexistence of clean, dirty, and grey innovations, this study contributes novel insights into the green transition of a critical industrial sector in a developing economy. The findings underscore the need for targeted R&D incentives, regulatory support, and startup-oriented policies to accelerate India's transition toward sustainable mobility.
{"title":"A patent landscape of green transition in the Indian automobile industry","authors":"Tsewang Stanzin, Ruchi Sharma","doi":"10.1016/j.wpi.2025.102409","DOIUrl":"10.1016/j.wpi.2025.102409","url":null,"abstract":"<div><div>The Indian automobile industry is experiencing a rapid technological transition, shaped by growing pressures for environmental sustainability. While scholarship has extensively examined the role of FDI in transferring clean technologies to developing economies, less attention has been paid to the evolving domestic innovation landscape and the contributions of new entrants. Addressing this gap, the present study employs patent-based analysis to map the trajectory of green and dirty technologies in India's automobile industry. Using international patent classification codes, co-occurrence network analysis, and revealed technological advantage indices, we track resident and non-resident patent filings, examine the portfolios of incumbents and startups, and explore technological linkages between clean, dirty, and grey innovations. Our results reveal a sustained increase in clean patenting activity, especially in electric vehicle technologies. However, internal combustion engine-related innovations continue to dominate due to path dependency and regulatory-driven grey innovation. Startups demonstrate high specialization in clean technologies, whereas incumbent firms retain diversified portfolios. By uncovering the heterogeneous roles of incumbents and startups and highlighting the coexistence of clean, dirty, and grey innovations, this study contributes novel insights into the green transition of a critical industrial sector in a developing economy. The findings underscore the need for targeted R&D incentives, regulatory support, and startup-oriented policies to accelerate India's transition toward sustainable mobility.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"83 ","pages":"Article 102409"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145528011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-10-08DOI: 10.1016/j.wpi.2025.102401
Christopher T. Lohrey , Kelvin W. Willoughby
This paper investigates how small and medium-sized enterprises (SMEs) can leverage intellectual property (IP) use to enhance their innovation performance. The existing literature on IP use is typically focused on large established corporations, or discrete strategy issues related to specific topics such as patent management and lacks a comprehensive overview of IP strategy challenges for SMEs. Our study addresses this gap in the literature by conducting a systematic literature review addressing the dynamics, requirements and benefits to SMEs of the strategic accumulation, maintenance and exploitation of IP rights. Our findings indicate that SMEs may improve their innovation performance, their overall business performance and their competitive positioning by treating the management of IP as a basic business function alongside orthodox management functions such as finance, marketing, operations, and R&D. This paper makes three key contributions. First, it deepens our understanding of how the use of IP affects business functions within SMEs. Second, it advances the strategy literature by highlighting IP as an impactful if not yet widely appreciated strategic domain for managers of SMEs. Third, it connects the innovation and technology management literature, in the organizational context of SMEs, with the intellectual property literature.
{"title":"Intellectual property and SMEs … What's the state of play?","authors":"Christopher T. Lohrey , Kelvin W. Willoughby","doi":"10.1016/j.wpi.2025.102401","DOIUrl":"10.1016/j.wpi.2025.102401","url":null,"abstract":"<div><div>This paper investigates how small and medium-sized enterprises (SMEs) can leverage intellectual property (IP) use to enhance their innovation performance. The existing literature on IP use is typically focused on large established corporations, or discrete strategy issues related to specific topics such as patent management and lacks a comprehensive overview of IP strategy challenges for SMEs. Our study addresses this gap in the literature by conducting a systematic literature review addressing the dynamics, requirements and benefits to SMEs of the strategic accumulation, maintenance and exploitation of IP rights. Our findings indicate that SMEs may improve their innovation performance, their overall business performance and their competitive positioning by treating the management of IP as a basic business function alongside orthodox management functions such as finance, marketing, operations, and R&D. This paper makes three key contributions. First, it deepens our understanding of how the use of IP affects business functions within SMEs. Second, it advances the strategy literature by highlighting IP as an impactful if not yet widely appreciated strategic domain for managers of SMEs. Third, it connects the innovation and technology management literature, in the organizational context of SMEs, with the intellectual property literature.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"83 ","pages":"Article 102401"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145267899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-10-22DOI: 10.1016/j.wpi.2025.102406
Heng Yang, Sheng Chen
Sustainable technologies are critical to Industry 5.0—owing to the carbon-neutrality and digital-transformation transitions. To systematically identify and evaluate key sustainable technologies, this research performed an extensive investigation of 11,253 patent documents spanning the period 2011–2025. It tackled the shortcomings of previous topic-modeling approaches and the limited incorporation of life-cycle prediction in previous research. It combined the BERTopic model with the logistic growth model—enhancing topic interpretability and enabling the dynamic assessment of technological trajectories—and thus established an integrated analytical framework. The results revealed nine core technologies that drive sustainability in Industry 5.0. Technologies that have already entered the saturation stage include wireless communications (Topic 1), smart terminals and wearables (Topic 2), human–computer interaction and data intelligence (Topic 5), advanced materials and metallurgical processing (Topic 6), optical communication and modular systems (Topic 7), and acoustic sensing and smart audio (Topic 8). In addition, computer vision (Topic 0) and energy storage and wireless power transfer (Topic 4) are projected to reach the saturation stage within the next three years. Among all the technologies analyzed, additive manufacturing (Topic 3) remains at a high-growth stage, suggesting considerable potential for further development and application. This study contributes to a better understanding of the sustainable innovation landscape of Industry 5.0 and offers specific policy implications for industry stakeholders and governments.
{"title":"Industry 5.0: Life-Cycle mapping of sustainable technologies using BERTopic-Driven patent analytics","authors":"Heng Yang, Sheng Chen","doi":"10.1016/j.wpi.2025.102406","DOIUrl":"10.1016/j.wpi.2025.102406","url":null,"abstract":"<div><div>Sustainable technologies are critical to Industry 5.0—owing to the carbon-neutrality and digital-transformation transitions. To systematically identify and evaluate key sustainable technologies, this research performed an extensive investigation of 11,253 patent documents spanning the period 2011–2025. It tackled the shortcomings of previous topic-modeling approaches and the limited incorporation of life-cycle prediction in previous research. It combined the BERTopic model with the logistic growth model—enhancing topic interpretability and enabling the dynamic assessment of technological trajectories—and thus established an integrated analytical framework. The results revealed nine core technologies that drive sustainability in Industry 5.0. Technologies that have already entered the saturation stage include wireless communications (Topic 1), smart terminals and wearables (Topic 2), human–computer interaction and data intelligence (Topic 5), advanced materials and metallurgical processing (Topic 6), optical communication and modular systems (Topic 7), and acoustic sensing and smart audio (Topic 8). In addition, computer vision (Topic 0) and energy storage and wireless power transfer (Topic 4) are projected to reach the saturation stage within the next three years. Among all the technologies analyzed, additive manufacturing (Topic 3) remains at a high-growth stage, suggesting considerable potential for further development and application. This study contributes to a better understanding of the sustainable innovation landscape of Industry 5.0 and offers specific policy implications for industry stakeholders and governments.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"83 ","pages":"Article 102406"},"PeriodicalIF":1.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-08-16DOI: 10.1016/j.wpi.2025.102386
Pietro Carlos Gonçalves Conceição , Natália Hlavnicka Miranda , Luiggi Cavalcanti Pessôa , Denilson de Jesus Assis , Jamille Santos Santana , Paulo Vitor França Lemos , Jania Betania Alves da Silva , Lucas Guimarães Cardoso , Karina Teixeira Magalhães-Guedes , Leonardo Moreira de Assunção , Carolina Oliveira de Souza
Polyhydroxyalkanoates (PHAs) have emerged as promising biodegradable alternatives to petrochemical plastics for packaging applications, aligning with global sustainability goals. This study presents a comprehensive analysis of the scientific and technological landscape of PHA-based packaging from 1992 to 2024, combining a systematic review of 4176 scientific articles with a patent landscape analysis of 3328 patent families. The results reveal a robust increase in academic research since 2015, focusing on enhancing mechanical, barrier, and antimicrobial properties through nanomaterials and bioactive additives. Patent trends show a technological evolution from basic PHA formulations to multifunctional, smart packaging systems. The food sector dominates application areas, while blending PHAs with polymers such as PLA, starch, and PBAT remains a key strategy to improve performance and reduce costs. China leads in patent filings, driven by strong regulatory support, whereas Japan and the U.S. contribute significantly through industrial innovation. Despite the high potential of PHAs, challenges such as production cost, thermal sensitivity, and limited university-industry partnerships persist. The findings highlight the need for intensified collaboration and continued R&D investment to advance PHA-based packaging technologies toward large-scale adoption.
{"title":"Advancing PHA-Based packaging: A patent and scientific landscape analysis for sustainable innovation","authors":"Pietro Carlos Gonçalves Conceição , Natália Hlavnicka Miranda , Luiggi Cavalcanti Pessôa , Denilson de Jesus Assis , Jamille Santos Santana , Paulo Vitor França Lemos , Jania Betania Alves da Silva , Lucas Guimarães Cardoso , Karina Teixeira Magalhães-Guedes , Leonardo Moreira de Assunção , Carolina Oliveira de Souza","doi":"10.1016/j.wpi.2025.102386","DOIUrl":"10.1016/j.wpi.2025.102386","url":null,"abstract":"<div><div>Polyhydroxyalkanoates (PHAs) have emerged as promising biodegradable alternatives to petrochemical plastics for packaging applications, aligning with global sustainability goals. This study presents a comprehensive analysis of the scientific and technological landscape of PHA-based packaging from 1992 to 2024, combining a systematic review of 4176 scientific articles with a patent landscape analysis of 3328 patent families. The results reveal a robust increase in academic research since 2015, focusing on enhancing mechanical, barrier, and antimicrobial properties through nanomaterials and bioactive additives. Patent trends show a technological evolution from basic PHA formulations to multifunctional, smart packaging systems. The food sector dominates application areas, while blending PHAs with polymers such as PLA, starch, and PBAT remains a key strategy to improve performance and reduce costs. China leads in patent filings, driven by strong regulatory support, whereas Japan and the U.S. contribute significantly through industrial innovation. Despite the high potential of PHAs, challenges such as production cost, thermal sensitivity, and limited university-industry partnerships persist. The findings highlight the need for intensified collaboration and continued R&D investment to advance PHA-based packaging technologies toward large-scale adoption.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"82 ","pages":"Article 102386"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144851774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The objective of this review is to discover systemic barriers and strategic possibilities that impact innovation, commercialization, and regulatory alignment by critically analyzing the patents of nanomedicine worldwide. The translational trajectory of nanomedicine is examined in relation to intellectual property (IP) frameworks, regulatory heterogeneity, and claim complexity.
Results
According to the report, the patent landscape is crowded and fragmented, with overlapping material and method claims delaying market entrance and driving up licensing costs by as much as 50 %. The intricacy of patent claims and disparate jurisdictional categorization schemes lead to protracted examination backlogs, which sometimes surpass 30 months. Timelines for patent drafting and clearance are complicated by regulatory misalignment, especially between the FDA, EMA, and other authorities. Early freedom-to-operate analyses, cross-licensing, and involvement in ISO/ASTM working groups are examples of strategic interventions that can reduce the number of transactions by 50 % and accelerate the time-to-market ratio by approximately 20 %. Reforms at the policy level, such as shared-IP incentives, specialist examiner tracks, and harmonized definitions (e.g., nanoparticle sizes of 1–100 nm), might reduce licensing costs by approximately 30 %. Patent landscape analysis in medicine and health care has transformed into a multidimensional, AI-powered endeavor integrating semantic extraction, graph theory, and economic modeling to reveal innovation hubs and strategic opportunities across diverse subfields. Clinical translation is facilitated, and public trust is increased when ethical, legal, and social factors are included throughout the R&D lifecycle. A robust and cohesive IP environment is necessary to realize the full potential of nanomedicine. This comprises an integrated regulatory-patent strategy, simplified patent office processes, enhanced examiner knowledge, and uniform definitions. In addition to increasing the quality and enforcement of patents, these reforms will increase competition, draw in investment, and hasten the introduction of nanomedicine advances to patients, which will ultimately lower healthcare costs and improve patient outcomes. To fully realize the therapeutic and financial promise of nanomedicine, this review discusses that standardizing patent definitions, expediting assessment procedures, and incorporating ethical frameworks are crucial. Innovation will be accelerated, prices will decrease, and patient access to cutting-edge treatments will be enhanced by a robust, internationally coordinated IP system.
{"title":"The patent landscape of Nanomedicine: Opportunities and obstacles","authors":"Amrita Singh , Sarita Rana , Mansi Trivedi , Abhay Kant Upadhyay , Omar Awad Alsaidan , Waleed H. Almalki , Salem Salman Almujri , Ankit Sahoo , Mahfoozur Rahman","doi":"10.1016/j.wpi.2025.102379","DOIUrl":"10.1016/j.wpi.2025.102379","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this review is to discover systemic barriers and strategic possibilities that impact innovation, commercialization, and regulatory alignment by critically analyzing the patents of nanomedicine worldwide. The translational trajectory of nanomedicine is examined in relation to intellectual property (IP) frameworks, regulatory heterogeneity, and claim complexity.</div></div><div><h3>Results</h3><div>According to the report, the patent landscape is crowded and fragmented, with overlapping material and method claims delaying market entrance and driving up licensing costs by as much as 50 %. The intricacy of patent claims and disparate jurisdictional categorization schemes lead to protracted examination backlogs, which sometimes surpass 30 months. Timelines for patent drafting and clearance are complicated by regulatory misalignment, especially between the FDA, EMA, and other authorities. Early freedom-to-operate analyses, cross-licensing, and involvement in ISO/ASTM working groups are examples of strategic interventions that can reduce the number of transactions by 50 % and accelerate the time-to-market ratio by approximately 20 %. Reforms at the policy level, such as shared-IP incentives, specialist examiner tracks, and harmonized definitions (e.g., nanoparticle sizes of 1–100 nm), might reduce licensing costs by approximately 30 %. Patent landscape analysis in medicine and health care has transformed into a multidimensional, AI-powered endeavor integrating semantic extraction, graph theory, and economic modeling to reveal innovation hubs and strategic opportunities across diverse subfields. Clinical translation is facilitated, and public trust is increased when ethical, legal, and social factors are included throughout the R&D lifecycle. A robust and cohesive IP environment is necessary to realize the full potential of nanomedicine. This comprises an integrated regulatory-patent strategy, simplified patent office processes, enhanced examiner knowledge, and uniform definitions. In addition to increasing the quality and enforcement of patents, these reforms will increase competition, draw in investment, and hasten the introduction of nanomedicine advances to patients, which will ultimately lower healthcare costs and improve patient outcomes. To fully realize the therapeutic and financial promise of nanomedicine, this review discusses that standardizing patent definitions, expediting assessment procedures, and incorporating ethical frameworks are crucial. Innovation will be accelerated, prices will decrease, and patient access to cutting-edge treatments will be enhanced by a robust, internationally coordinated IP system.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"82 ","pages":"Article 102379"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144750302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-31DOI: 10.1016/j.wpi.2025.102378
Moumita Sarkar , Tapas Kumar Bandyopadhyay
Biodegradable metal implants are a significant innovation in medical science, offering temporary mechanical support and gradually dissolving within the body, thus avoiding the need for a second surgery. This study presents a comprehensive patent landscape analysis of metallic biodegradable implants: examining key trends, technological advancements, and major patent holders. Analysing 2114 global patent filings, the study identifies leading advancements in composition, manufacturing techniques, surface modifications, and clinical applications. There is clear information about the legal status of approximately 65 % of the total patent records, including granted patents that are still in force and those that have lapsed or discontinued due to non-renewal or other reasons. Specifically for India, a total of 177 individual patent application records involving filings in Indian jurisdiction resulted from a targeted screening procedure, with 99.4 % remaining active and 0.6 % marked as expired. However, biodegradable implant patent filings in India remain below expectations. This is attributed to the stringent application of Sections 3(i), 3(d), 3(f), and 3(e) of The Patent Act, 1970, that aim to minimize social costs in medical technology. These findings offer valuable insights for researchers, policymakers, and industry stakeholders navigating India's evolving patent landscape and future commercialization of metallic biodegradable implants.
{"title":"Patenting trends in biodegradable implant: An analysis","authors":"Moumita Sarkar , Tapas Kumar Bandyopadhyay","doi":"10.1016/j.wpi.2025.102378","DOIUrl":"10.1016/j.wpi.2025.102378","url":null,"abstract":"<div><div>Biodegradable metal implants are a significant innovation in medical science, offering temporary mechanical support and gradually dissolving within the body, thus avoiding the need for a second surgery. This study presents a comprehensive patent landscape analysis of metallic biodegradable implants: examining key trends, technological advancements, and major patent holders. Analysing 2114 global patent filings, the study identifies leading advancements in composition, manufacturing techniques, surface modifications, and clinical applications. There is clear information about the legal status of approximately 65 % of the total patent records, including granted patents that are still in force and those that have lapsed or discontinued due to non-renewal or other reasons. Specifically for India, a total of 177 individual patent application records involving filings in Indian jurisdiction resulted from a targeted screening procedure, with 99.4 % remaining active and 0.6 % marked as expired. However, biodegradable implant patent filings in India remain below expectations. This is attributed to the stringent application of Sections 3(i), 3(d), 3(f), and 3(e) of The Patent Act, 1970, that aim to minimize social costs in medical technology. These findings offer valuable insights for researchers, policymakers, and industry stakeholders navigating India's evolving patent landscape and future commercialization of metallic biodegradable implants.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"82 ","pages":"Article 102378"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-08-04DOI: 10.1016/j.wpi.2025.102381
Shunsuke Sakaoka, Shingo Kano
The application of artificial intelligence (AI) in the pharmaceutical industry has rapidly expanded in recent years. To quantitatively assess this emerging trend, previous studies have conducted bibliometric analyses using publication databases to elucidate leading affiliations, research themes, and the contributions and research focuses of key players, including mega pharma, big IT firms, AI startups, and academic institutions. However, quantitative analyses that leverage patent databases to capture these significant shifts and assess the contributions of the key players are scarce. This study investigated technological trends in AI applications within the pharmaceutical industry and clarify the roles and strategic focuses of key players through patent analysis. A total of 1365 AI-related pharmaceutical patent applications in the United States between 2000 and 2023 were identified. Through a detailed analysis of patents, we revealed that AI is strategically employed across critical business domains, including drug discovery, drug development, diagnosis, manufacturing, marketing, and healthcare. Moreover, the study unveiled the specific business areas where each key player has focused their AI-driven initiatives and historical contributions to AI applications in the pharmaceutical industry. The findings underscore both patent and literature analyses are essential to comprehensively assess AI applications and contributions of key players in the pharmaceutical industry.
{"title":"Quantitative insights on artificial intelligence in the pharmaceutical industry: A patent-basis analysis of technological trends and key players","authors":"Shunsuke Sakaoka, Shingo Kano","doi":"10.1016/j.wpi.2025.102381","DOIUrl":"10.1016/j.wpi.2025.102381","url":null,"abstract":"<div><div>The application of artificial intelligence (AI) in the pharmaceutical industry has rapidly expanded in recent years. To quantitatively assess this emerging trend, previous studies have conducted bibliometric analyses using publication databases to elucidate leading affiliations, research themes, and the contributions and research focuses of key players, including mega pharma, big IT firms, AI startups, and academic institutions. However, quantitative analyses that leverage patent databases to capture these significant shifts and assess the contributions of the key players are scarce. This study investigated technological trends in AI applications within the pharmaceutical industry and clarify the roles and strategic focuses of key players through patent analysis. A total of 1365 AI-related pharmaceutical patent applications in the United States between 2000 and 2023 were identified. Through a detailed analysis of patents, we revealed that AI is strategically employed across critical business domains, including drug discovery, drug development, diagnosis, manufacturing, marketing, and healthcare. Moreover, the study unveiled the specific business areas where each key player has focused their AI-driven initiatives and historical contributions to AI applications in the pharmaceutical industry. The findings underscore both patent and literature analyses are essential to comprehensively assess AI applications and contributions of key players in the pharmaceutical industry.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"82 ","pages":"Article 102381"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-03DOI: 10.1016/j.wpi.2025.102375
Chang Xu , Tingrui Zhang , Jie Zhang , Fei Tan , Zongguang Tai , Zhongjian Chen
Psoriasis, a chronic systemic inflammatory disease affecting over 125 million people globally (2–3 % prevalence) with substantial economic burden (annual treatment costs exceeding 15 billion and projected to reach 30 billion by 2027), drives demand for advanced diagnostic and therapeutic devices. This study aims to provide developers with current intelligence on technological advancements in psoriasis management, identifying active R&D areas and aiding resource allocation. Patent data from global intellectual property offices and the PatSnap Wisdom Sprout database were analysed to track the maturity of diagnostic and treatment technologies from 1975 to 2023. The study reveals a focus on therapeutic devices, particularly phototherapy, with improvements in light sources, power supplies, heat management, safety, flexibility, cleanliness, and intelligent control. Diagnostic equipment development concentrates on image detection technologies, emphasizing cleanliness, adaptability, multifunctionality, smart device integration, and lightweight design. To address the evolving needs of psoriasis treatment, it is recommended to integrate beneficial technologies, enhancing interdisciplinary collaboration, and innovating to overcome technological challenges.
{"title":"The global patent landscape of devices for psoriasis diagnosis and treatment","authors":"Chang Xu , Tingrui Zhang , Jie Zhang , Fei Tan , Zongguang Tai , Zhongjian Chen","doi":"10.1016/j.wpi.2025.102375","DOIUrl":"10.1016/j.wpi.2025.102375","url":null,"abstract":"<div><div>Psoriasis, a chronic systemic inflammatory disease affecting over 125 million people globally (2–3 % prevalence) with substantial economic burden (annual treatment costs exceeding 15 billion and projected to reach 30 billion by 2027), drives demand for advanced diagnostic and therapeutic devices. This study aims to provide developers with current intelligence on technological advancements in psoriasis management, identifying active R&D areas and aiding resource allocation. Patent data from global intellectual property offices and the PatSnap Wisdom Sprout database were analysed to track the maturity of diagnostic and treatment technologies from 1975 to 2023. The study reveals a focus on therapeutic devices, particularly phototherapy, with improvements in light sources, power supplies, heat management, safety, flexibility, cleanliness, and intelligent control. Diagnostic equipment development concentrates on image detection technologies, emphasizing cleanliness, adaptability, multifunctionality, smart device integration, and lightweight design. To address the evolving needs of psoriasis treatment, it is recommended to integrate beneficial technologies, enhancing interdisciplinary collaboration, and innovating to overcome technological challenges.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"82 ","pages":"Article 102375"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144549566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-11DOI: 10.1016/j.wpi.2025.102377
Paula dos Passos Menezes , Alcimary Bispo Santos , Maria Eduarda da Conceição Andrade , José Adão Carvalho Nascimento Júnior , Marcelo Cavalcante Duarte , Shanmugan Saravanan , Mairim Russo Serafini
Patent review is a time-consuming process because it involves the complexity of the documents with technical language and unpatterned files. Automating steps like data extraction can make technological prospects faster and more efficient. Thus, this study aimed to compare the use of an Artificial Intelligence (AI) tool to automate the data extraction of patents. A traditional patent review was conducted in Espacenet and WIPO databases, using the test subject: AI tools for skin cancer detection. Two independent reviewers performed the patent screening in Excel traditionally, and the data extraction step was manually made both and using SciSpace. SciSpace was 13.2 times faster than the traditional way and correctly extracted 69.7 % of information. Although it is a promising tool to accelerate the patent review process, it is crucial to author review the final version to ensure its accuracy and the representation of its ideas.
{"title":"Innovative data extraction in patent reviews with SciSpace","authors":"Paula dos Passos Menezes , Alcimary Bispo Santos , Maria Eduarda da Conceição Andrade , José Adão Carvalho Nascimento Júnior , Marcelo Cavalcante Duarte , Shanmugan Saravanan , Mairim Russo Serafini","doi":"10.1016/j.wpi.2025.102377","DOIUrl":"10.1016/j.wpi.2025.102377","url":null,"abstract":"<div><div>Patent review is a time-consuming process because it involves the complexity of the documents with technical language and unpatterned files. Automating steps like data extraction can make technological prospects faster and more efficient. Thus, this study aimed to compare the use of an Artificial Intelligence (AI) tool to automate the data extraction of patents. A traditional patent review was conducted in Espacenet and WIPO databases, using the test subject: AI tools for skin cancer detection. Two independent reviewers performed the patent screening in Excel traditionally, and the data extraction step was manually made both and using SciSpace. SciSpace was 13.2 times faster than the traditional way and correctly extracted 69.7 % of information. Although it is a promising tool to accelerate the patent review process, it is crucial to author review the final version to ensure its accuracy and the representation of its ideas.</div></div>","PeriodicalId":51794,"journal":{"name":"World Patent Information","volume":"82 ","pages":"Article 102377"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144596276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-05DOI: 10.1016/j.wpi.2025.102376
Olena Litvinova , Michel-Edwar Mickael , Gernot Gerger , Andy Wai Kan Yeung , Ahmed Fatimi , Hossam Haick , Atanas G. Atanasov , Harald Willschke
This article presents a patent and bibliometric analysis of the scientific landscape of the use of graphene-based biosensors and their prospects in the field of digital medicine.
A study of patent activity in the field of graphene biosensors (2005–2025) showed an increase in interest, especially since 2015, with a peak in 2021, with China, the U.S., and the World Intellectual Property Organization as the most active offices. Web of Science revealed 16,551 articles, with active growth since 2010, focusing primarily on analytical chemistry, nanotechnology, and electrochemistry. China and India lead the way in research.
Bibliometric analysis using VOSviewer identified four key clusters reflecting the main research directions of graphene biosensors: medical diagnostics, integration with digital technologies, the use of metals and nanomaterials, and analytical methods in biosensor technologies. The distribution of keywords over time analyzed with VOSviewer and CiteSpace indicates increasing digitalization in graphene biosensor research from 2020, underscoring the growing interest in flexible, highly sensitive sensors and their integration with digital platforms for diagnosis and analysis.
Despite the high potential of graphene biosensors, there are challenges pointed out in the literature, such as scaling, biocompatibility, and cost issues, as well as the need to address safety and reliability concerns.
本文介绍了使用石墨烯为基础的生物传感器的科学景观及其在数字医学领域的前景的专利和文献计量学分析。一项关于石墨烯生物传感器领域（2005-2025年）专利活动的研究显示，人们对该领域的兴趣有所增加，尤其是自2015年以来，2021年达到高峰，中国、美国和世界知识产权组织是最活跃的专利局。Web of Science公布了16,551篇文章，自2010年以来一直在积极增长，主要集中在分析化学、纳米技术和电化学方面。中国和印度在研究方面处于领先地位。使用VOSviewer进行文献计量分析，确定了反映石墨烯生物传感器主要研究方向的四个关键集群：医疗诊断、与数字技术的集成、金属和纳米材料的使用以及生物传感器技术中的分析方法。利用VOSviewer和CiteSpace分析的关键词随时间的分布表明，从2020年开始，石墨烯生物传感器研究的数字化程度将不断提高，这表明人们对柔性、高灵敏度传感器及其与数字诊断和分析平台的集成越来越感兴趣。尽管石墨烯生物传感器具有很高的潜力，但文献中指出了一些挑战，如缩放、生物相容性和成本问题，以及需要解决安全性和可靠性问题。
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