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Recurrent pulmonary embolism complicated with myotonic dystrophy type 1 复发性肺栓塞并发 1 型肌营养不良症
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-14 DOI: 10.1002/jgf2.709
Hiraku Sedogawa MD, Masahiro Yabe MD, Keiichi Tsuchida MD, Yasuo Hirose MD

Myotonic dystrophy is a hereditary neurological disease. While cardiovascular complications have been recognized, recent reports indicate that it increases the risk of deep vein thrombosis and pulmonary embolism (DVT/PE) compared to other dystrophies and healthy individuals with dyspraxia and a history of DVT as risk factors. It is important to consider myotonic dystrophy in patients with repeated idiopathic DVT/PE and to provide appropriate medical consultation.

肌营养不良症是一种遗传性神经系统疾病。虽然心血管并发症已得到公认,但最近的报告显示,与其他肌营养不良症和健康人相比,肌营养不良症增加了深静脉血栓形成和肺栓塞(DVT/PE)的风险,而运动障碍和深静脉血栓形成史是风险因素。对于反复出现特发性深静脉血栓/肺栓塞的患者,考虑肌营养不良症并提供适当的医疗咨询非常重要。
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引用次数: 0
Point-of-care ultrasound for Lemierre's syndrome during the COVID-19 pandemic: A case report 在 COVID-19 大流行期间对莱米尔综合征进行护理点超声检查:病例报告
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-14 DOI: 10.1002/jgf2.708
Yosuke Kawai MD, Kei Nishiyama MD, PhD

Lemierre's syndrome is a fatal condition characterized by septic thrombophlebitis of the internal jugular vein (IJV). Early diagnosis of Lemierre's syndrome in primary care remains challenging because of its rarity and common initial symptoms like fever and sore throat. The COVID-19 pandemic has increased the difficulty of diagnosis, along with many diagnostic delays. Herein, we report a case in which an IJV thrombus was detected using point-of-care ultrasound (POCUS), leading to the diagnosis of Lemierre's syndrome. During the COVID-19 pandemic, POCUS was a simple and noninvasive technique for screening Lemierre's syndrome without radiation and low droplet exposure.

勒米尔综合征是一种以颈内静脉(IJV)化脓性血栓性静脉炎为特征的致命疾病。由于其罕见性以及发热和咽喉痛等常见的初期症状,在初级保健中早期诊断勒米尔氏综合征仍具有挑战性。COVID-19 大流行增加了诊断难度,同时也造成了许多诊断延误。在本文中,我们报告了一例使用床旁超声(POCUS)检测到 IJV 血栓并最终确诊为 Lemierre 综合征的病例。在 COVID-19 大流行期间,POCUS 是一种简单、无创的莱米尔综合征筛查技术,没有辐射,飞沫暴露量低。
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引用次数: 0
Practice locations of physicians with highly educated spouses in Japan: A cross-sectional study using National Census Data 日本高学历配偶医生的执业地点:利用全国人口普查数据进行的横断面研究
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-14 DOI: 10.1002/jgf2.710
Atsushi Miyawaki MD, PhD, Jun Tomio MD, PhD

Background

Having highly educated spouses may influence physicians' choice of practice location.

Methods

We analyzed a representative physician sample in the 2020 Japan Population Census.

Results

Regression analyses adjusting for physicians' characteristics showed that physicians married to highly educated (with a graduate degree) spouses were less likely to practice in low physician supply areas (LPSAs) than other married physicians (adjusted, 7.8% vs. 9.1%; adjusted odds ratio, 0.84; 95% CI, 0.72–0.98).

Conclusion

Having highly educated spouses was associated with a lower likelihood of practicing in LPSAs. Qualitative research is needed to explore how spousal academic attainment influences physicians' practice location choices.

我们分析了 2020 年日本人口普查中具有代表性的医生样本。调整了医生特征的回归分析表明,与其他已婚医生相比,配偶受过高等教育(拥有研究生学位)的医生在低医生供应区(LPSAs)执业的可能性较低(调整后,7.8% vs. 9.1%;调整后的几率比,0.84;95% CI,0.72-0.98)。需要进行定性研究来探讨配偶的学历如何影响医生的执业地点选择。
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引用次数: 0
A trial of structured debate as a self-learning method for students and young healthcare providers to discuss social issues in general and family medicine: A case report in Japan 试行结构化辩论,作为学生和年轻医护人员讨论全科和家庭医学中社会问题的自学方法:日本案例报告
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-27 DOI: 10.1002/jgf2.706
Tatsuki Ikejiri MD, Jeonse Lee MD, Natsuki Yokoyama BS, Arisa Hakariya MD, Yuki Otsuka MD, PhD, Hayase Hakariya PhD
<p>Structured debate is broadly played by university students and graduates as a competition. The educational benefits of debates, such as fostering critical thinking, are acknowledged across various disciplines.<span><sup>1</sup></span> Hence, we proposed using debates as a self-learning method for medical students and young healthcare providers. Herein, we report a trial where debate serves as a tool for self-learning in Japan.</p><p>Our debate adhered to the systematic procedures outlined by the Japan Debate Association.<span><sup>2</sup></span> Time allocation was slightly modified (Table S1). We held debates using Zoom, with approximately 5–10 voluntary participants: medical students and young healthcare providers. A “plan (agenda)” was collaboratively based on participants' daily observations and interests (Table 1). The participants were divided into two sides: the “pro” (Affirmative side) and the “con” (Negative side), enabling the debate. After the debate, a panel of three judges decided the persuasiveness of each side. The roles of “pro” and “con” were blindly assigned by a third party, irrespective of individuals' opinions on the topic. We performed four debates, as shown below (Table 1). Participants' motivation for these topics is also described.</p><p>After each debate, time for reflection was provided. Summarizing the participants' feedback, we found three distinctive characteristics of learning through structured debate as follows. First, students and early-career healthcare providers demonstrated their capability of thinking and researching actively (more easily with a single axis) when given the role of agreeing or disagreeing with a topic in which their interest was vague rather than with no axis. Second, developing discussions within a certain structure will foster the ability to think logically. Lastly, the students will be able to have a multifaceted viewpoint through arguments from both sides, rather than from one point of view.</p><p>Of note, our structured debate was conducted online. Given the increased attention toward online educational systems in light of the COVID-19 pandemic, this trial could potentially serve as a promising alternative tool in the future.</p><p>As a limitation, our debates were performed without the involvement of leadership experts, as we intended to provide a voluntarily investigating platform to explore topics of participants' interest. Consequently, the quality of the debates depended markedly on the participants' motivation. Moreover, given that participants of this trial were sufficiently motivated at least enough to invest their precious time voluntarily, well-organized and appealing instructions should be required to install our method in the usual classroom education. For instance, supervision by senior group mentors, who have already acquired the credit, during participants' preparation stage may be beneficial. Prior discussion and consultation with such mentors could also serve as studen
有组织的辩论是大学生和毕业生广泛参与的一项竞赛活动。1 因此,我们建议将辩论作为医学生和年轻医护人员的自学方法。在此,我们报告了一项在日本将辩论作为自学工具的试验。我们的辩论遵循了日本辩论协会制定的系统程序2 。我们使用 Zoom 进行辩论,约有 5-10 名自愿参与者:医学生和年轻的医疗服务提供者。根据参与者的日常观察和兴趣,我们共同制定了 "计划(议程)"(表 1)。参与者被分为正反两方:"正方"(肯定方)和 "反方"(否定方),从而展开辩论。辩论结束后,由三位评委组成的评审团决定双方的说服力。正方 "和 "反方 "的角色由第三方盲目分配,与个人对主题的看法无关。我们进行了四场辩论,如下表所示(表 1)。每次辩论结束后,我们都会给参与者留出思考时间。总结参与者的反馈,我们发现通过结构化辩论学习有以下三个显著特点。首先,学生和初入职场的医护人员在被赋予同意或不同意他们感兴趣的模糊话题的角色时,比在没有轴心的情况下更容易表现出他们积极思考和研究的能力(在单一轴心的情况下更容易)。其次,在一定的结构中开展讨论将培养逻辑思维能力。最后,学生们将能够通过正反两方面的论证,而不是从一个观点出发,获得多方面的观点。值得注意的是,我们的结构化辩论是在网上进行的。鉴于 COVID-19 的流行,人们对在线教育系统的关注度越来越高,这一试验有可能在未来成为一种很有前途的替代工具。因此,辩论的质量在很大程度上取决于参与者的积极性。此外,鉴于本次试验的参与者至少有足够的积极性来自愿投入宝贵的时间,因此,要将我们的方法应用于通常的课堂教学中,就必须要有精心组织的、有吸引力的指导。例如,在参与者的准备阶段,由已经获得学分的资深小组导师进行指导可能会有所裨益。事先与这些导师进行讨论和协商,也可以为学员把关,避免遗漏要点,保持方向。此外,我们对辩论赛教育效果的评估还不够充分,因为我们只收集了叙述性反馈。然而,值得注意的是,只有少数研究评估了结构化辩论在医学领域的教育效果;这些报告包括各种有争议的话题,如医学伦理、医疗保健系统和急诊医学等。3-5 如果能从不同角度进行更全面的评估,将会强化我们的建议,即利用结构化辩论作为学生和早期医学专业人员的医学教育平台。
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引用次数: 0
Exploring social determinants of health in primary care: Approaches to increase research inclusivity 探索初级保健中健康的社会决定因素:提高研究包容性的方法
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-21 DOI: 10.1002/jgf2.705
Takuya Maejima MD, Junki Mizumoto MD, Gemmei Iizuka MD, PhD, Maho Haseda MD, PhD
<p>Research on the social determinants of health (SDH) aims to foster a healthier, more equitable society by reducing health disparities. Nonetheless, primary care researchers often face challenges in engaging marginalized populations in their studies. It is essential to explore diverse methodologies to promote inclusive research.</p><p>During the fifth annual Primary Care Research (PCR) Connect conference, dedicated to primary care research in Japan, we held a symposium to discuss strategies for enhancing inclusivity in SDH research.</p><p>Using large-scale datasets from multiple centers or municipalities offers the advantage of evaluating the subtle effects of meso- and macro-level factors on individual health and their heterogeneities. However, the exclusion of individuals because of healthcare access barriers, language barriers, absence from official databases, or unstable housing situations can introduce sampling and selection biases. Such biases may compromise the studies' validity and generalizability of those findings.<span><sup>1</sup></span> Therefore, the following studies focusing on marginalized populations highlight their potential benefits in specific contexts.</p><p>By tailoring surveys to fit the target population, researchers can gather responses from individuals typically overlooked in large-scale surveys, allowing insights into their characteristics and concerns, including their lived experiences. For instance, investigations focus on individuals residing in marginalized communities, such as street dwellers living around train stations<span><sup>2</sup></span> or residents in impoverished neighborhoods.<span><sup>3</sup></span> Collaboration with local authorities ensures access to this data, essential for these studies. Furthermore, researchers should endeavor to mitigate health disparities by implementing interventions.</p><p>Qualitative research offers researchers a window into the lived experiences, thoughts, and emotions of socially marginalized individuals. For instance, qualitative inquiry holds the potential to unveil the barriers perceived by women with a history of substance use, transgender individuals, or youth contemplating suicide,<span><sup>4</sup></span> during their interactions within primary care settings.</p><p>Case reports can elucidate the detailed experiences of patients facing complex social adversities.<span><sup>5</sup></span> Reports concentrating on SDH equip primary care professionals with critical insights for managing SDH-related challenges in daily practice. Maintaining patient confidentiality is a critical responsibility for all reporters.</p><p>Although we did not refer to a systematic review or scoping review in the conference, these reviews will synthesize the available evidence and identify evidence gaps.</p><p>In conclusion, research on SDH can employ diverse methodologies to illuminate the experiences of marginalized populations. Primary care professionals, often the initial point of cont
对健康的社会决定因素(SDH)进行研究的目的是通过缩小健康差距,促进建立一个更健康、更公平的社会。然而,初级保健研究人员在让边缘化人群参与研究时常常面临挑战。在第五届日本初级医疗研究(PCR)联接年会期间,我们举办了一场研讨会,讨论提高 SDH 研究包容性的策略。使用来自多个中心或城市的大规模数据集具有评估中观和宏观因素对个人健康的微妙影响及其异质性的优势。然而,由于医疗保健获取障碍、语言障碍、官方数据库缺失或住房状况不稳定等原因而将个人排除在外,可能会带来抽样和选择偏差。1 因此,以下以边缘化人群为重点的研究强调了其在特定情况下的潜在益处。通过定制适合目标人群的调查,研究人员可以收集到在大规模调查中通常被忽视的个人的回答,从而深入了解他们的特点和关注点,包括他们的生活经历。例如,调查的重点是居住在边缘化社区的个人,如居住在火车站周围的街头流浪者2 或贫困社区的居民3 。此外,研究人员应努力通过实施干预措施来减少健康差异。定性研究为研究人员提供了一个了解社会边缘化个人的生活经历、思想和情感的窗口。例如,定性调查有可能揭示有药物使用史的妇女、变性人或酝酿自杀的青少年4 在初级保健环境中互动时所感受到的障碍。案例报告可以阐明面临复杂社会逆境的患者的详细经历。总之,有关 SDH 的研究可以采用多种方法来阐明边缘化人群的经历。初级保健专业人员往往是面临社会挑战的患者的最初接触点,他们在利用自身地位放大这些人的声音并参与关注其健康和福祉的研究方面发挥着关键作用。
{"title":"Exploring social determinants of health in primary care: Approaches to increase research inclusivity","authors":"Takuya Maejima MD,&nbsp;Junki Mizumoto MD,&nbsp;Gemmei Iizuka MD, PhD,&nbsp;Maho Haseda MD, PhD","doi":"10.1002/jgf2.705","DOIUrl":"10.1002/jgf2.705","url":null,"abstract":"&lt;p&gt;Research on the social determinants of health (SDH) aims to foster a healthier, more equitable society by reducing health disparities. Nonetheless, primary care researchers often face challenges in engaging marginalized populations in their studies. It is essential to explore diverse methodologies to promote inclusive research.&lt;/p&gt;&lt;p&gt;During the fifth annual Primary Care Research (PCR) Connect conference, dedicated to primary care research in Japan, we held a symposium to discuss strategies for enhancing inclusivity in SDH research.&lt;/p&gt;&lt;p&gt;Using large-scale datasets from multiple centers or municipalities offers the advantage of evaluating the subtle effects of meso- and macro-level factors on individual health and their heterogeneities. However, the exclusion of individuals because of healthcare access barriers, language barriers, absence from official databases, or unstable housing situations can introduce sampling and selection biases. Such biases may compromise the studies' validity and generalizability of those findings.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; Therefore, the following studies focusing on marginalized populations highlight their potential benefits in specific contexts.&lt;/p&gt;&lt;p&gt;By tailoring surveys to fit the target population, researchers can gather responses from individuals typically overlooked in large-scale surveys, allowing insights into their characteristics and concerns, including their lived experiences. For instance, investigations focus on individuals residing in marginalized communities, such as street dwellers living around train stations&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; or residents in impoverished neighborhoods.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; Collaboration with local authorities ensures access to this data, essential for these studies. Furthermore, researchers should endeavor to mitigate health disparities by implementing interventions.&lt;/p&gt;&lt;p&gt;Qualitative research offers researchers a window into the lived experiences, thoughts, and emotions of socially marginalized individuals. For instance, qualitative inquiry holds the potential to unveil the barriers perceived by women with a history of substance use, transgender individuals, or youth contemplating suicide,&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; during their interactions within primary care settings.&lt;/p&gt;&lt;p&gt;Case reports can elucidate the detailed experiences of patients facing complex social adversities.&lt;span&gt;&lt;sup&gt;5&lt;/sup&gt;&lt;/span&gt; Reports concentrating on SDH equip primary care professionals with critical insights for managing SDH-related challenges in daily practice. Maintaining patient confidentiality is a critical responsibility for all reporters.&lt;/p&gt;&lt;p&gt;Although we did not refer to a systematic review or scoping review in the conference, these reviews will synthesize the available evidence and identify evidence gaps.&lt;/p&gt;&lt;p&gt;In conclusion, research on SDH can employ diverse methodologies to illuminate the experiences of marginalized populations. Primary care professionals, often the initial point of cont","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.705","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving outcomes of type 2 diabetes mellitus patients in primary care with Chronic Care Model: A narrative review 通过慢性病护理模式改善基层医疗机构 2 型糖尿病患者的治疗效果:叙述性综述
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-20 DOI: 10.1002/jgf2.659
Arwa Ahmed Al-Qahtani MD

Designed and implemented over two decades ago, the Chronic Care Model is a well-established chronic disease management framework that has steered several healthcare systems in successfully improving the clinical outcomes of patients with type 2 diabetes mellitus. Research evidence cements the role of the Chronic Care Model (with its six key elements of organization of healthcare delivery system, self-management support, decision support, delivery system design, clinical information systems, and community resources and policies) as an integrated framework to revamp the type 2 diabetes mellitus-related clinical practice and care that betters the patient care and clinical outcomes. The current review is an evidence-lit summary of importance of use of Chronic Care Model in primary care and their impact on clinical outcomes for patients afflicted with one of the most debilitating metabolic diseases, type 2 diabetes mellitus.

慢性病护理模式是二十多年前设计和实施的一种行之有效的慢性病管理框架,它引导多个医疗保健系统成功改善了 2 型糖尿病患者的临床疗效。研究证据证明,慢性病护理模式(包括医疗保健服务系统的组织、自我管理支持、决策支持、服务系统设计、临床信息系统以及社区资源和政策等六个关键要素)是一个综合框架,可用于改进与 2 型糖尿病相关的临床实践和护理,从而改善患者护理和临床疗效。本综述以证据为基础,总结了在初级保健中使用慢性病护理模式的重要性及其对 2 型糖尿病这种最令人衰弱的代谢性疾病患者的临床治疗效果的影响。
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引用次数: 0
Reasons for encounters, diagnoses, and admission rate among emergency referrals at an urban primary care clinic in Japan: A retrospective cohort study 日本城市初级保健诊所急诊转诊患者的就诊原因、诊断和入院率:回顾性队列研究
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-16 DOI: 10.1002/jgf2.704
Yoshinao Satoi MD, Masato Matsushima MD, MPH, PhD, Hiroyoshi Iwata MD, PhD

Background

Comprehensive understanding of emergency referrals (EmR), encompassing reasons for encounters (RFEs) and diagnoses, is crucial for primary care physicians (PCPs). Comparing EmR rates and subsequent admission rates can potentially enhance the quality of primary care for EmR practice. However, no study has evaluated RFEs among patients with EmRs. This study aimed to identify RFE/diagnosis in relation to subsequent admission among patients receiving EmR.

Methods

We conducted a retrospective cohort study at an urban family physician teaching clinic in Kawasaki City, Japan. Our cohort recruited consecutive EmR episodes with their medical records and admissions confirmed through response letters from receiving hospitals. Using the 2nd edition of the International Classification of Primary Care, we explored the frequency of RFEs and diagnoses, calculating EmR rates and admission rates as primary outcomes. Bivariate analyses were employed to compare admission and non-admission cases.

Results

The present study encompassed 162 EmR episodes out of 47,901 visits, yielding an EmR rate of 3.38/1000 visits. Among 153 completely followed episodes, 99 patients were emergently admitted, resulting in a 64.7% admission rate. The admission group exhibited significantly higher age and a greater prevalence of dementia. Descriptive analysis revealed fever and pneumonia as the most frequent RFE and diagnosis, respectively, with significant differences between admission and non-admission groups.

Conclusions

The present study reports EmR and admission rates following EmR, highlighting differences in patient characteristics, RFEs, and diagnoses. The findings offer insights to enhance PCPs' EmR practices and serve as a benchmark for the scope of EmR practice.

全面了解急诊转诊(EmR),包括就诊原因(RFE)和诊断,对初级保健医生(PCP)至关重要。比较急诊转诊率和后续入院率有可能提高急诊转诊实践的初级保健质量。然而,还没有研究对 EmR 患者的 RFE 进行过评估。我们在日本川崎市的一家城市家庭医生教学诊所开展了一项回顾性队列研究。我们在川崎市的城市家庭医生教学诊所进行了一项回顾性队列研究。我们的队列招募了连续接受 EmR 的患者,他们的医疗记录和入院情况均通过接收医院的回信得到确认。我们使用第二版《国际初级保健分类》(International Classification of Primary Care)探讨了RFE的频率和诊断,并将EMR率和入院率作为主要结果进行计算。本研究从 47,901 次就诊中收集了 162 次 EmR,EmR 率为 3.38/1000。在 153 个完全跟踪的病例中,有 99 名患者急诊入院,入院率为 64.7%。入院组患者的年龄明显偏高,痴呆症的发病率也更高。描述性分析显示,发热和肺炎分别是最常见的急诊病例和诊断,入院组和非入院组之间存在显著差异。本研究报告了急诊病例和急诊病例后的入院率,强调了患者特征、急诊病例和诊断的差异。本研究报告了 EmR 后的 EmR 和入院率,强调了患者特征、RFE 和诊断的差异。研究结果为加强初级保健医生的 EmR 实践提供了启示,并可作为 EmR 实践范围的基准。
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引用次数: 0
A large increase in Group A streptococcus bacteremia in the 2 month short period in 2024; report from a tertiary care hospital in Chiba, Japan 2024 年短短两个月内 A 群链球菌菌血症大幅增加;日本千叶县一家三级医院的报告
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-10 DOI: 10.1002/jgf2.702
Kanta Kurasawa MD, Misato Yoshida MD, Masahiko Nakao MD, Emiri Muranaka MD, Yushi Hachisu DVM, Mitsuru Kishizawa, Takashi Kikuchi DVM, Ryota Hase MD
<p>Following the COVID-19 pandemic, several European countries and the United States reported a marked increase in scarlet fever and invasive Group A streptococcus (GAS) infection.<span><sup>1, 2</sup></span> Although this trend is likely because of reduced exposure and the immunity gap associated with a strict mask policy or social distancing during the pandemic, it is also thought to be related to the emergence and spread of the more toxigenic M1 UK variant.<span><sup>3</sup></span> In Japan, an increasing number of cases of streptococcal toxic shock syndrome (STSS) caused by GAS have been reported since July 2023.<span><sup>4</sup></span></p><p>In the first 2 months of 2024, a large increase in GAS bacteremia was detected at the Japanese Red Cross Narita Hospital, a tertiary teaching hospital with 710 beds. A total of six cases of bacteremia (2.37906 cases/1000 hospital admissions) were detected during the 2 months (Table 1). The median age was 45 years (range: 34–75 years). No patient was severely immunocompromised. The most common focus of infection was pneumonia with empyema (n = 3). The median Pitt bacteremia score and SOFA score were 2 and 3.5, respectively. Among six isolates from these cases, five were serotype T1 and positive for allele-specific PCR for the M1UK lineage.<span><sup>5</sup></span> Two patients died within the first day of hospitalization, and most of the surviving patients required surgical intervention. Given this increase, we analyzed the distribution of cases of GAS bacteremia during 2016–2023. The average number of cases of GAS bacteremia per year was 3.25 cases during 2016–2019 (0.21125 cases/1000 hospital admissions) and 1.75 cases during 2020–2023 (0.11654/1000 hospital admissions), respectively.</p><p>Circulation of the M1<sub>UK</sub> variant strain may have contributed to the large increase in STSS cases in Japan. Previous reports have suggested that the M1<sub>UK</sub> lineage may drive the observed increase in GAS infections in Europe.<span><sup>3</sup></span> In Japan, the M1<sub>UK</sub> strains account for only 6.4% of all 780 strains collected at eight reference centers during 2018–2023, but nine out of 19 strains were found to be the M1<sub>UK</sub> strains in reported STSS cases since August 2023 in the Kanto region.<span><sup>4</sup></span> The incidence of GAS bacteremia in our hospital during the 2 month short period in 2024 was much higher than that before and during the COVID-19 pandemic, and most cases were caused by the M1<sub>UK</sub> variant strain, which is consistent with the trend in the surveillance data shown above.</p><p>In conclusion, this report suggests that the M1<sub>UK</sub> variant has been spread in certain areas in Japan and is likely to contribute to the large increase in invasive GAS infections.</p><p>Physicians should be cautious about this significant increase.</p><p>None.</p><p>The authors report that there are no competing interests to disclose.</p><p>This study was approve
COVID-19大流行后,一些欧洲国家和美国报告猩红热和侵袭性A组链球菌(GAS)感染明显增加。1, 2 尽管这一趋势可能是由于大流行期间严格的口罩政策或社会疏远导致接触减少和免疫差距,但也被认为与毒性更强的M1 UK变异株的出现和传播有关。在日本,自 2023 年 7 月以来,由 GAS 引起的链球菌中毒性休克综合征(STSS)病例的报告数量不断增加。4 在 2024 年的头两个月,日本红十字成田医院(一家拥有 710 张病床的三级教学医院)发现 GAS 菌血症病例大量增加。在这两个月中,共发现 6 例菌血症病例(2.37906 例/1000 住院病例)(表 1)。中位年龄为 45 岁(34-75 岁)。没有患者免疫力严重低下。最常见的感染病灶是伴有肺水肿的肺炎(3 例)。皮特菌血症评分和 SOFA 评分的中位数分别为 2 分和 3.5 分。在这些病例的 6 个分离株中,5 个为血清 T1 型,M1UK 系等位基因特异性 PCR 检测呈阳性。鉴于这一增长情况,我们分析了 2016-2023 年期间 GAS 菌血症病例的分布情况。2016-2019年期间,每年平均GAS菌血症病例数分别为3.25例(0.21125例/1000入院人数)和2020-2023年期间的1.75例(0.11654例/1000入院人数)。3 在日本,M1UK 菌株仅占 2018-2023 年期间在 8 个参考中心收集的全部 780 株菌株的 6.4%,但自 2023 年 8 月以来,在关东地区报告的 STSS 病例中,发现 19 株菌株中有 9 株是 M1UK 菌株。我院在 2024 年短短 2 个月期间的 GAS 菌血症发病率远高于 COVID-19 大流行之前和期间的发病率,且大多数病例由 M1UK 变异株引起,这与上述监测数据的趋势一致。总之,本报告表明,M1UK 变异株已在日本某些地区扩散,很可能是导致侵袭性 GAS 感染大量增加的原因。本研究获得了日本红十字成田医院伦理委员会的批准,但前提是必须对所有个人数据保密(批准号:JRCNH-895-01)。
{"title":"A large increase in Group A streptococcus bacteremia in the 2 month short period in 2024; report from a tertiary care hospital in Chiba, Japan","authors":"Kanta Kurasawa MD,&nbsp;Misato Yoshida MD,&nbsp;Masahiko Nakao MD,&nbsp;Emiri Muranaka MD,&nbsp;Yushi Hachisu DVM,&nbsp;Mitsuru Kishizawa,&nbsp;Takashi Kikuchi DVM,&nbsp;Ryota Hase MD","doi":"10.1002/jgf2.702","DOIUrl":"10.1002/jgf2.702","url":null,"abstract":"&lt;p&gt;Following the COVID-19 pandemic, several European countries and the United States reported a marked increase in scarlet fever and invasive Group A streptococcus (GAS) infection.&lt;span&gt;&lt;sup&gt;1, 2&lt;/sup&gt;&lt;/span&gt; Although this trend is likely because of reduced exposure and the immunity gap associated with a strict mask policy or social distancing during the pandemic, it is also thought to be related to the emergence and spread of the more toxigenic M1 UK variant.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; In Japan, an increasing number of cases of streptococcal toxic shock syndrome (STSS) caused by GAS have been reported since July 2023.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;In the first 2 months of 2024, a large increase in GAS bacteremia was detected at the Japanese Red Cross Narita Hospital, a tertiary teaching hospital with 710 beds. A total of six cases of bacteremia (2.37906 cases/1000 hospital admissions) were detected during the 2 months (Table 1). The median age was 45 years (range: 34–75 years). No patient was severely immunocompromised. The most common focus of infection was pneumonia with empyema (n = 3). The median Pitt bacteremia score and SOFA score were 2 and 3.5, respectively. Among six isolates from these cases, five were serotype T1 and positive for allele-specific PCR for the M1UK lineage.&lt;span&gt;&lt;sup&gt;5&lt;/sup&gt;&lt;/span&gt; Two patients died within the first day of hospitalization, and most of the surviving patients required surgical intervention. Given this increase, we analyzed the distribution of cases of GAS bacteremia during 2016–2023. The average number of cases of GAS bacteremia per year was 3.25 cases during 2016–2019 (0.21125 cases/1000 hospital admissions) and 1.75 cases during 2020–2023 (0.11654/1000 hospital admissions), respectively.&lt;/p&gt;&lt;p&gt;Circulation of the M1&lt;sub&gt;UK&lt;/sub&gt; variant strain may have contributed to the large increase in STSS cases in Japan. Previous reports have suggested that the M1&lt;sub&gt;UK&lt;/sub&gt; lineage may drive the observed increase in GAS infections in Europe.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; In Japan, the M1&lt;sub&gt;UK&lt;/sub&gt; strains account for only 6.4% of all 780 strains collected at eight reference centers during 2018–2023, but nine out of 19 strains were found to be the M1&lt;sub&gt;UK&lt;/sub&gt; strains in reported STSS cases since August 2023 in the Kanto region.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; The incidence of GAS bacteremia in our hospital during the 2 month short period in 2024 was much higher than that before and during the COVID-19 pandemic, and most cases were caused by the M1&lt;sub&gt;UK&lt;/sub&gt; variant strain, which is consistent with the trend in the surveillance data shown above.&lt;/p&gt;&lt;p&gt;In conclusion, this report suggests that the M1&lt;sub&gt;UK&lt;/sub&gt; variant has been spread in certain areas in Japan and is likely to contribute to the large increase in invasive GAS infections.&lt;/p&gt;&lt;p&gt;Physicians should be cautious about this significant increase.&lt;/p&gt;&lt;p&gt;None.&lt;/p&gt;&lt;p&gt;The authors report that there are no competing interests to disclose.&lt;/p&gt;&lt;p&gt;This study was approve","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.702","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140990817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic cerebrospinal fluid leak can cause amyotrophic lateral sclerosis mimic 慢性脑脊液漏可导致肌萎缩性脊髓侧索硬化症的模仿症
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-10 DOI: 10.1002/jgf2.691
Satoshi Saito MD, Ryotaro Ikeguchi MD, PhD, Kazuo Kitagawa MD, PhD

Chronic cerebrospinal fluid leak with spinal cord compression can mimic the symptoms of ALS, with a snake-eyes appearance on MRI.

慢性脑脊液漏伴有脊髓压迫可模拟 ALS 的症状,在核磁共振成像上表现为蛇眼状。
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引用次数: 0
The relation between resident mentorship and in-training examination scores: A nation-wide, cross-sectional study in Japan 住院医师指导与培训中考试成绩之间的关系:日本全国横断面研究
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-10 DOI: 10.1002/jgf2.703
Kohta Katayama MD, PhD, Yuji Nishizaki MD, MPH, PhD, Toshihiko Takada MD, MPH, MSc, PhD, Koshi Kataoka MMSc, Nathan Houchens MD, Taro Shimizu MD, PhD, MSc, MPH, MBA, Yu Yamamoto MD, Takashi Watari MD, MHQS, MCTM, PhD, Yasuharu Tokuda MD, MPH, Yoshiyuki Ohira MD, PhD

Background

Mentorship is a dynamic reciprocal relationship, wherein a novice (mentee) grows with the encouragement of an advanced careerist (mentor). It is widely implemented in medical training programs. However, there are few reports on mentorship's educational effects in the Japanese context. This study investigated the association between mentorship and in-training examination scores during a clinical residency program in Japan.

Methods

A cross-sectional study was conducted in Japan, involving first and second year postgraduate (PGY-1 and PGY-2) residents set to take the General Medicine In-Training Examination (GM-ITE) at the end of the academic year of 2021. The GM-ITE, developed by a non-profit organization in 2012, assesses the overall clinical knowledge of PGY-1 and PGY-2 residents. Data on mentorship were obtained through an electronic survey, conducted immediately after the GM-ITE. The association between a resident's self-reported identification of at least one mentor and GM-ITE score was analyzed at multiple levels.

Results

Of the total 4929 residents, 3266 (66.3%) reported having mentors. However, there was no association between mentorship and GM-ITE scores (adjusted score difference [aSD] = −0.22; 95% confidence interval [95% CI]: −0.64 to 0.19).

Conclusions

Among Japanese residents, in-training examination scores were not associated with mentorship.

导师制是一种动态的互惠关系,新手(被指导者)在高级职业导师(指导者)的鼓励下不断成长。导师制在医学培训项目中广泛实施。然而,有关导师制在日本的教育效果的报道却很少。本研究调查了日本临床住院医师培训项目中导师制与在训考试成绩之间的关系。本研究在日本进行了一项横断面研究,对象是将于2021学年结束时参加全科医学在训考试(GM-ITE)的一年级和二年级住院医师(PGY-1和PGY-2)。GM-ITE 由一家非营利组织于 2012 年开发,用于评估 PGY-1 和 PGY-2 住院医师的整体临床知识。有关导师指导的数据是在 GM-ITE 结束后立即通过电子调查获得的。在总共 4929 名住院医师中,有 3266 人(66.3%)报告有导师。然而,导师与 GM-ITE 分数之间没有关联(调整后分数差异 [aSD] = -0.22;95% 置信区间 [95% CI]:-0.64 至 0.19):-在日本住院医师中,培训中考试成绩与导师关系无关。
{"title":"The relation between resident mentorship and in-training examination scores: A nation-wide, cross-sectional study in Japan","authors":"Kohta Katayama MD, PhD,&nbsp;Yuji Nishizaki MD, MPH, PhD,&nbsp;Toshihiko Takada MD, MPH, MSc, PhD,&nbsp;Koshi Kataoka MMSc,&nbsp;Nathan Houchens MD,&nbsp;Taro Shimizu MD, PhD, MSc, MPH, MBA,&nbsp;Yu Yamamoto MD,&nbsp;Takashi Watari MD, MHQS, MCTM, PhD,&nbsp;Yasuharu Tokuda MD, MPH,&nbsp;Yoshiyuki Ohira MD, PhD","doi":"10.1002/jgf2.703","DOIUrl":"10.1002/jgf2.703","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Mentorship is a dynamic reciprocal relationship, wherein a novice (mentee) grows with the encouragement of an advanced careerist (mentor). It is widely implemented in medical training programs. However, there are few reports on mentorship's educational effects in the Japanese context. This study investigated the association between mentorship and in-training examination scores during a clinical residency program in Japan.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional study was conducted in Japan, involving first and second year postgraduate (PGY-1 and PGY-2) residents set to take the General Medicine In-Training Examination (GM-ITE) at the end of the academic year of 2021. The GM-ITE, developed by a non-profit organization in 2012, assesses the overall clinical knowledge of PGY-1 and PGY-2 residents. Data on mentorship were obtained through an electronic survey, conducted immediately after the GM-ITE. The association between a resident's self-reported identification of at least one mentor and GM-ITE score was analyzed at multiple levels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the total 4929 residents, 3266 (66.3%) reported having mentors. However, there was no association between mentorship and GM-ITE scores (adjusted score difference [aSD] = −0.22; 95% confidence interval [95% CI]: −0.64 to 0.19).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Among Japanese residents, in-training examination scores were not associated with mentorship.</p>\u0000 </section>\u0000 </div>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.703","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140992812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of General and Family Medicine
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