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Epidermolysis bullosa for primary care providers: A practical review 初级保健提供者的大疱性表皮松解症:一个实用的回顾
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-04-16 DOI: 10.1002/jgf2.70014
Kennedy Sparling BS, Judith O'Haver PhD, RN, CPNP-PC, Muayad Shahin BA, Amanda Damon APRN, Nichole Halliburton MSN, APRN, CNP, Kellie Badger BS, RN, Mariam Iqneibi MD, Beth Moeves APRN, Harper N. Price MD, Emily S. Gorell DO, MS

Epidermolysis bullosa (EB) is a group of genetic skin diseases, which manifest as fragile skin and blistering in addition to many extracutaneous conditions. Pediatricians and primary care providers play an integral role in managing these patients with multifaceted care needs. There are many resources to navigate treating the various manifestations of EB and to assist with the partnership between pediatricians, dermatologists, and other specialists. There are also newly approved therapies for treating some forms of EB. As patients may only attend the multidisciplinary clinic for the management of their condition at designated intervals, the primary care provider becomes the first point of contact in many acute or healthcare maintenance visits. Using the resources and tips discussed herein, the pediatrician can work with the rest of the medical team to best optimize the clinical outcomes of patients with EB.

大疱性表皮松解症(EB)是一组遗传性皮肤病,除了许多皮肤外,还表现为皮肤脆弱和起泡。儿科医生和初级保健提供者在管理这些具有多方面护理需求的患者方面发挥着不可或缺的作用。有许多资源可以导航治疗EB的各种表现,并协助儿科医生,皮肤科医生和其他专家之间的合作。也有新批准的治疗某些形式EB的疗法。由于患者只能在指定的时间间隔内到多学科诊所就诊,因此初级保健提供者成为许多急症或保健维护就诊的第一个接触点。利用本文讨论的资源和提示,儿科医生可以与医疗团队的其他成员合作,以最佳地优化EB患者的临床结果。
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引用次数: 0
Association between preexisting long-term care needs and in-hospital mortality and long-term outcomes in older inpatients with pneumonia: A retrospective cohort study 老年肺炎住院患者既往长期护理需求与住院死亡率和长期预后之间的关系:一项回顾性队列研究
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-04-11 DOI: 10.1002/jgf2.70016
Jumpei Taniguchi MD, Hayato Yamana MD, PhD, Yuichiro Matsuo MD, Yusuke Sasabuchi MD, PhD, Hiroki Matsui PhD, Takahide Kohro MD, PhD, Hideo Yasunaga MD, PhD

Background

Limited evidence exists regarding the impact of baseline functional and cognitive impairments on the outcomes of patients with pneumonia.

Methods

We used medical and long-term care administrative databases in a prefecture in Japan that contained care need levels assessed using the national standardized certification system. We identified patients aged ≥65 years who were hospitalized for pneumonia between June 2014 and October 2018. The impairments were classified into four categories based on estimated total daily care time: no care needs, support levels 1–2, care needs level 1 (estimated care time of 25–49 min), care needs level 2–3 (50–89 min), and care needs level 4–5 (≥90 min). The primary outcome was the in-hospital mortality rate. Secondary outcomes were death and care needs at 6 months and 1 year after admission. We evaluated the outcomes based on care need levels and conducted multivariate analyses adjusting for potential confounders.

Results

A total of 15,537 patients (mean age 83.9 years) were included. The in-hospital mortality rates for patients with no care needs, support levels 1–2 and care needs level 1, care needs levels 2–3, and care needs levels 4–5 were 10.5%, 15.9%, 21.1%, and 24.7%, respectively. The proportions of patients who died or experienced worsening care needs at 6 months were 43.6%, 60.4%, 60.0%, and 50.2%, respectively. Multivariable analyses demonstrated independent associations of preexisting care needs with both in-hospital mortality and long-term outcomes.

Conclusion

Preexisting long-term care needs are associated with short- and long-term outcomes in older inpatients with pneumonia.

背景:关于基线功能和认知障碍对肺炎患者预后影响的证据有限。方法我们使用日本一个县的医疗和长期护理管理数据库,其中包含使用国家标准化认证系统评估的护理需求水平。我们确定了2014年6月至2018年10月期间因肺炎住院的年龄≥65岁的患者。根据估计的每日总护理时间将缺陷分为四类:无护理需要、支持等级1 - 2、护理需要等级1(估计护理时间为25-49分钟)、护理需要等级2-3(50-89分钟)和护理需要等级4-5(≥90分钟)。主要终点是住院死亡率。次要结局是入院后6个月和1年的死亡和护理需求。我们根据护理需求水平评估结果,并对潜在混杂因素进行多变量分析。结果共纳入15537例患者,平均年龄83.9岁。无护理需要、支持等级1 - 2和护理需要等级1、护理需要等级2-3和护理需要等级4-5患者的住院死亡率分别为10.5%、15.9%、21.1%和24.7%。6个月死亡或护理需求恶化的患者比例分别为43.6%、60.4%、60.0%和50.2%。多变量分析表明,先前存在的护理需求与住院死亡率和长期预后之间存在独立关联。结论住院老年肺炎患者既往长期护理需求与短期和长期预后相关。
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引用次数: 0
Enhancing decision-making capacity assessments in primary care: A practical guide for family physicians 加强初级保健决策能力评估:家庭医生实用指南
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-04-08 DOI: 10.1002/jgf2.70013
Victor Ajluni MD

Family physicians play a crucial role in assessing decision-making capacity, yet face challenges because of time constraints and lack of training. This article presents a structured framework to guide these assessments, ensuring ethical and efficient evaluations. By applying key principles—clarifying the decision at hand, assessing understanding, appreciation, reasoning, and expression—physicians can navigate complex cases while balancing patient autonomy with appropriate medical care.

家庭医生在评估决策能力方面发挥着至关重要的作用,但由于时间限制和缺乏培训,他们面临着挑战。本文提出了一个结构化的框架来指导这些评估,确保道德和有效的评估。通过应用关键原则——澄清手头的决定,评估理解、欣赏、推理和表达——医生可以在处理复杂病例的同时,平衡患者的自主权和适当的医疗护理。
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引用次数: 0
Healthcare professionals' experiences related LGBTQ+ patients and colleagues at their workplace: Descriptive research in Japan 医疗保健专业人员在工作场所与LGBTQ+患者和同事相关的经历:日本的描述性研究
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-03-29 DOI: 10.1002/jgf2.70012
Junki Mizumoto MD, PhD, Eriko Kono MD, Eriko Yoshida MD, PhD

Background

LGBTQ+ patients often face discrimination in a healthcare setting, and LGBTQ+ healthcare professionals experience disproportionately high levels of workplace stress. The purpose of this research is (i) to explore healthcare professionals' experiences about LGBTQ+ patients and colleagues and (ii) evaluate LGBTQ+ healthcare professionals' experiences, challenges, and concerns in their workplace.

Methods

The Sexual Orientation, Gender Identity, and Gender Expression (SOGIE) Project of the Japan Federation of Democratic Medical Institutions (MIN-IREN) developed and distributed a questionnaire to assess staff experiences related to SOGI at their workplace.

Results

A total of 6216 professionals participated. Of these, 443 (7.1%) reported witnessing or hearing about discrimination against LGBTQ+ patients, and 330 (5.3%) reported similar incidents involving LGBTQ+ colleagues. The most common source of knowledge was mass media. Approximately half of the participants described their workplace as welcoming to LGBTQ+ patients and colleagues. While 705 (11.3%) participants openly identified as allies, 2129 (34.3%) considered themselves allies at heart without expressing it. Some initiatives were identified to be prioritized. Among 133 (2.1%) participants identifying themselves as LGBTQ+, 41 participants reported disclosing their SOGI to some members in their workplaces. The most common workplace difficulty was the assumption of heterosexuality in all events.

Conclusions

Discrimination against the LGBTQ+ population in healthcare settings is prevalent. Many healthcare professionals who hold allyship at heart face some barriers to express it. LGBTQ+ healthcare professionals face various difficulties at their workplaces. Collaboration with LGBTQ+ healthcare professionals is needed to foster inclusivity and support a more affirming healthcare environment.

LGBTQ+患者在医疗保健环境中经常面临歧视,LGBTQ+医疗保健专业人员承受着不成比例的高水平工作压力。本研究的目的是:(i)探讨医疗保健专业人员对LGBTQ+患者和同事的体验;(ii)评估LGBTQ+医疗保健专业人员在工作场所的体验、挑战和担忧。方法日本民主医疗机构联合会(MIN-IREN)的性取向、性别认同和性别表达(SOGIE)项目编制并发放了一份调查问卷,对工作场所员工的SOGI相关经历进行评估。结果共有6216名专业人员参与。其中,443人(7.1%)报告目睹或听到对LGBTQ+患者的歧视,330人(5.3%)报告了涉及LGBTQ+同事的类似事件。最常见的知识来源是大众传媒。大约一半的参与者表示,他们的工作场所欢迎LGBTQ+患者和同事。有705人(11.3%)公开承认自己是盟友,但有2129人(34.3%)认为自己是盟友,但没有表达出来。确定了一些需要优先考虑的倡议。在133名(2.1%)自称为LGBTQ+的参与者中,41名参与者报告在工作场所向一些成员透露了他们的SOGI。最常见的职场难题是在所有情况下都假定自己是异性恋。结论卫生保健机构对LGBTQ+人群的歧视普遍存在。许多将盟友关系放在心上的医疗保健专业人员在表达这种关系时面临一些障碍。LGBTQ+医疗保健专业人员在工作场所面临各种困难。需要与LGBTQ+医疗保健专业人员合作,以促进包容性并支持更加肯定的医疗保健环境。
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引用次数: 0
Addressing healthcare needs in an inaugural family medicine clinic in a core city in Japan: Mixed-methods research 解决日本核心城市首个家庭医学诊所的医疗保健需求:混合方法研究
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-03-21 DOI: 10.1002/jgf2.777
Junki Mizumoto MD, PhD, Maki Nishimura MD, MSc, Naoko Ishikawa MD, MSc, PhD, Kana Hisatake MD, Eri Satake, Shizuka Yamamoto, Shota Tsuno

Background

There exists little research elucidating the benefits of family medicine clinics for community with ample specialist healthcare resources.

Methods

We conducted mixed-methods research. Within the inaugural family medicine clinic, the following data was collected during the initial 2 months: (i) newly identified healthcare needs among scheduled outpatients; (ii) management of outpatients with complex health and social needs; and (iii) provision of home-visit care. Newly detected health care needs were summarized qualitatively using a summative content analysis. Patients' complexity was quantitatively scored using the Japanese version of the Patient Centred Assessment Method.

Results

Physicians identified 156 new needs and 13 complex cases. The complexity of patients receiving home-visit care was high.

Conclusions

This study demonstrates that an inaugural family medicine clinic adeptly addressed a diverse spectrum of patients' healthcare needs.

背景很少有研究阐明家庭医学诊所对专科医疗资源充足的社区的益处。方法采用混合方法进行研究。在开业的家庭医学诊所内,在最初的2个月内收集了以下数据:(i)在预定门诊患者中新确定的医疗保健需求;(ii)管理有复杂健康和社会需要的门诊病人;(三)提供家访服务。使用总结性内容分析对新发现的卫生保健需求进行定性总结。使用日本版的以患者为中心的评估方法对患者的复杂性进行定量评分。结果医师发现156例新增需求和13例复杂病例。接受家访护理的患者复杂程度高。结论:本研究表明,一个首次家庭医学诊所熟练地解决了病人的各种医疗保健需求。
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引用次数: 0
Shining stars in the sky on the gastric mucosa 天上的星星在胃粘膜上闪闪发光
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-03-12 DOI: 10.1002/jgf2.70011
Kosuke Minaga MD, PhD, Hajime Honjo MD, PhD, Tomohiro Watanabe MD, PhD, Masatoshi Kudo MD, PhD

We report a rare case of an elderly Japanese man diagnosed with sporadic gastric Burkitt lymphoma. Esophagogastroduodenoscopy showed nodular and ulcerated lesions in the lesser curvature of the stomach. Pathological analysis of showed that the gastric lesions are characterized by a diffuse and dense accumulation of dark atypical lymphocytes (night) and a scattered distribution of bright foamy macrophages (stars) that give the classic “starry sky” appearance.

我们报告一例罕见的日本老年男性被诊断为散发性胃伯基特淋巴瘤。食管胃十二指肠镜检查显示胃小弯结节和溃疡性病变。病理分析显示,胃病变表现为黑色非典型淋巴细胞弥漫性密集聚集(夜)和明亮泡沫状巨噬细胞分散分布(星),呈典型的“星空”样。
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引用次数: 0
“The future”: Interpretative phenomenological analysis of general practitioners' experiences of co-employed clinical psychologists “未来”:全科医生与临床心理学家合作经验的解释性现象学分析
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-24 DOI: 10.1002/jgf2.774
Katie Monnickendam D.Clin.Psy, Peter Keohane D.Clin.Psy, Rebecca Magill D.Clin.Psy

Background

General practice is overwhelmed and understaffed. New models and modalities must be considered from the front door of healthcare. Like general practitioners (GPs), clinical psychologists are qualified to work across the age range and transdiagnostically.

Aim

To explore GPs' understanding of the role of a clinical psychologist and to examine what is helpful and unhelpful for GPs about working alongside a clinical psychologist within general practice.

Design and Setting

This research took place within a primary care general practice in the United Kingdom.

Method

Seven qualified GPs were recruited as participants using a purposive sampling method. Interpretative phenomenological analysis was used to analyze participant's experiences of working alongside clinical psychologists.

Results

Three superordinate themes and 12 subordinate themes were identified. First, GP clinical psychologists support patients directly by providing preventative care, reducing stigma, and offering a different perspective. Second, they support GP well-being and contribute to emotional and behavioral changes in staff. Third, they help to alleviate pressures on wider systems, ease navigation of external services, challenge dominant systems within healthcare, and support community interventions.

Conclusion

GP clinical psychologists impact general practice in multiple ways: indirectly through patient care, by GPs themselves, and by addressing wider systems. Future research is encouraged to explore the perspectives of other staff members and patient's experiences.

背景:全科医生不堪重负,人手不足。必须从医疗保健的前门考虑新的模式和模式。与全科医生(gp)一样,临床心理学家有资格跨年龄范围和跨诊断工作。目的探讨全科医生对临床心理学家角色的理解,并研究全科医生与临床心理学家一起工作对全科医生有什么帮助和没有什么帮助。设计和背景本研究在英国的一家初级保健全科诊所进行。方法采用有目的抽样方法,招募7名符合条件的全科医生作为研究对象。解释现象学分析用于分析参与者与临床心理学家一起工作的经历。结果共识别出3个上级主题和12个下级主题。首先,全科医生临床心理学家通过提供预防性护理、减少耻辱感和提供不同的观点来直接支持患者。其次,他们支持全科医生的福祉,并有助于员工的情绪和行为改变。第三,它们有助于减轻更广泛系统的压力,简化外部服务的导航,挑战医疗保健中的主导系统,并支持社区干预。结论:全科医生临床心理学家以多种方式影响全科实践:间接通过病人护理,全科医生自己,并通过解决更广泛的系统。鼓励未来的研究探索其他工作人员的观点和患者的经验。
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引用次数: 0
Video review by utilizing asynchronous video communication platform 利用异步视频通信平台进行视频审核
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-21 DOI: 10.1002/jgf2.70005
Yuki Otsuka MD, PhD, Eiko Mitsuda MD, Yukichika Yamamoto MD, Atsushi Kato MD, Mano Soshi MD, Masaya Higuchi MD, MPH, Mikako Obika MD, PhD, Fumio Otsuka MD, PhD, Tadayuki Hashimoto MD, MPH

Background

Video review is widely recognized as an effective method for teaching communication; however, it can increase educators' workload and learners' stress.

Methods

We utilized Tsucom, an online platform developed by BonBon, Inc., which enables asynchronous video communication instead of traditional styles. An 11-min and 42-s consultation video from a fifth-year resident was uploaded, and 10 physicians provided 30 text-based feedback.

Results

In this pilot survey, the utility and ease of use were rated 4.4 and 4.1 out of 5, respectively.

Conclusions

While asynchronous online video reviews provided flexibility and greater participation, challenges remain, and further trials and evaluations were deemed necessary.

视频复习作为一种有效的教学交际方法,得到了广泛的认可;然而,它会增加教育者的工作量和学习者的压力。方法利用BonBon, Inc.开发的在线平台Tsucom,可以实现异步视频通信,而不是传统的方式。上传了一段5年住院医师11分42秒的咨询视频,10位医生提供了30条基于文本的反馈。结果在本次试点调查中,实用性和易用性分别获得4.4分和4.1分(满分5分)。尽管异步在线视频评论提供了灵活性和更大的参与度,但挑战依然存在,进一步的试验和评估被认为是必要的。
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引用次数: 0
Early detection of cerebrospinal fluid/serum glucose ratio: A promising value for mortality prognosis in patients with acute bacterial meningitis 早期检测脑脊液/血清葡萄糖比:对急性细菌性脑膜炎患者死亡率预后的有希望的价值
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-20 DOI: 10.1002/jgf2.70004
Nasrin Khodashenas MD, Rouzbeh Rajaei Ghafouri MD, Asghar Jafari Rouhi MD, Moloud Balafar MD

Background/Aims

Given that acute bacterial meningitis (ABM), as community-acquired meningitis, is considered a life-threatening medical emergency, early diagnosis and immediate onset of antibiotic therapy are of great importance. Here, we aimed to compare both the laboratory and glucometer assessment of cerebrospinal fluid (CSF)/serum glucose ratio in patients with suspected ABM. In addition, the prognostic value of the CSF/serum glucose ratio on the mortality rate was also evaluated.

Methods

In this cross-sectional, single-center study, all demographic and clinical characteristics of patients who attended the emergency department were evaluated. A total of 200 patients with clinical suspicion of ABM underwent lumbar puncture (LP) and were simultaneously recruited for CSF and serum glucose measurement using both laboratory tests and a point-of-care glucometer device. Data analysis was performed using SPSS ver. 20.0.

Results

Out of 200 suspected subjects with a mean age of 52.66 ± 6.64 years (male = 113, 56.5%), 23 patients (11.5%) were identified with confirmed ABM. The study findings showed a close correlation between the laboratory and glucometer-measured CSF/serum glucose ratio. The sensitivity and specificity of the glucose ratio measured by the laboratory test were 91.3% and 86.4%, respectively. A similar result was also observed by glucometer measurement (Sensitivity: 91.3%, Specificity: 89.3%, p < 0.001). However, the mean time needed for CSF glucose measurement was significantly longer in the laboratory method compared to the glucometer-based assessment (p < 0.0001). Notably, the CSF/serum glucose ratio was considerably lower in deceased patients (n = 9, p < 0.05).

Conclusion

Despite the similar accuracy of the CSF/serum glucose ratio using either a laboratory test or glucometer for ABM diagnosis, the present study highlighted that the laboratory turnaround time was significantly improved using a glucometer, which could be considered a reliable aid to the prognosis of mortality.

背景/目的鉴于急性细菌性脑膜炎(ABM)作为社区获得性脑膜炎,被认为是危及生命的医疗紧急情况,早期诊断和立即开始抗生素治疗非常重要。在这里,我们的目的是比较实验室和血糖仪评估疑似ABM患者的脑脊液(CSF)/血清葡萄糖比率。此外,还评估了脑脊液/血清葡萄糖比值对死亡率的预后价值。方法在这项横断面、单中心研究中,对急诊科就诊患者的所有人口统计学和临床特征进行评估。共有200名临床怀疑为ABM的患者进行了腰椎穿刺(LP),并同时招募了CSF和血清葡萄糖测量,使用实验室测试和即时血糖仪设备。数据分析采用SPSS ver软件。20.0. 结果200例疑似患者(平均年龄52.66±6.64岁,男性113例,占56.5%)中,23例(11.5%)被确诊为ABM。研究结果显示实验室和血糖仪测量的脑脊液/血清葡萄糖比率密切相关。实验室检测葡萄糖比值的敏感性为91.3%,特异性为86.4%。血糖仪测量也观察到类似的结果(灵敏度:91.3%,特异性:89.3%,p < 0.001)。然而,与基于血糖仪的评估相比,实验室方法中脑脊液葡萄糖测量所需的平均时间明显更长(p < 0.0001)。值得注意的是,死亡患者的脑脊液/血清葡萄糖比值明显较低(n = 9, p < 0.05)。结论:尽管脑脊液/血清葡萄糖比使用实验室测试或血糖仪诊断ABM的准确性相似,但本研究强调,使用血糖仪可显着改善实验室周转时间,这可以被认为是对死亡率预后的可靠帮助。
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引用次数: 0
Extreme hypercalcemia secondary to parathyroid adenoma obscured by excessive coffee consumption and premature ventricular complexes 甲状旁腺瘤继发的极端高钙血症被过量的咖啡摄入和过早的心室复合物所掩盖
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-14 DOI: 10.1002/jgf2.754
Yuval Avidan MD, Sameer Kassem MD, PhD

Severe hypercalcemia has an arrhythmogenic effect. We present a case of a young male falsely diagnosed with premature ventricular complexes attributed to heavy coffee consumption, while symptoms and electrocardiographic findings of hypercalcemia were disregarded. Delayed work-up identified extreme hypercalcemia, and subsequently, parathyroid adenoma was diagnosed. Medical and surgical management resulted in complete resolution. The misdiagnosis led to a substantial diagnostic delay.

严重的高钙血症具有致心律失常的作用。我们报告了一例年轻男性因大量饮用咖啡而被误诊为室性早衰,而高钙血症的症状和心电图结果却被忽视。延迟检查发现极度高钙血症,随后诊断为甲状旁腺瘤。内科和外科治疗导致完全解决。误诊导致了严重的诊断延误。
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引用次数: 0
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Journal of General and Family Medicine
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