Emre Erkal, Bedriye Cansu Demirkiran, Şerife Köleoğlu, Sevgi Demir Çam
Background : Vaccines have positive effects on the course of epidemics. This study was conducted to determine individuals’ attitudes toward coronavirus disease-2019 (COVID-19) vaccines, their health fatalism, and factors affecting these. Methods : This cross-sectional study included 944 participants living in Turkey, who were included in the study by snowball sampling, one of the nonprobability random sampling methods. Participant information form, attitudes toward the COVID-19 vaccine scale, and religious health fatalism scale were used to collect the study data. Independent sample t-test, one-way analysis of variance and Pearson correlation analysis were used in the data analysis. Results : Participants had mean positive attitudes toward COVID-19 vaccine score of 3.63 ± 1.14, mean negative attitudes toward COVID-19 vaccine score of 3.44 ± 0.91, and mean health fatalism score of 45.75 ± 17.43. Negative and significant correlations were found between participants’ mean health fatalism score and their mean p ositive attitudes score ( r = −0.213) and their mean negative attitude score ( r = −0.362) ( p < 0.001). Conclusions : Individuals were found to have high positive and low negative attitudes toward COVID-19 vaccines and moderate levels of health fatalism. Individuals with high health fatalism had low positive and high negative attitudes toward COVID-19 vaccines.
{"title":"Determination of Individuals’ Attitudes Toward COVID-19 Vaccines and Health Fatalism: A Cross-sectional Study from Turkey","authors":"Emre Erkal, Bedriye Cansu Demirkiran, Şerife Köleoğlu, Sevgi Demir Çam","doi":"10.7454/msk.v27i1.1404","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1404","url":null,"abstract":"Background : Vaccines have positive effects on the course of epidemics. This study was conducted to determine individuals’ attitudes toward coronavirus disease-2019 (COVID-19) vaccines, their health fatalism, and factors affecting these. Methods : This cross-sectional study included 944 participants living in Turkey, who were included in the study by snowball sampling, one of the nonprobability random sampling methods. Participant information form, attitudes toward the COVID-19 vaccine scale, and religious health fatalism scale were used to collect the study data. Independent sample t-test, one-way analysis of variance and Pearson correlation analysis were used in the data analysis. Results : Participants had mean positive attitudes toward COVID-19 vaccine score of 3.63 ± 1.14, mean negative attitudes toward COVID-19 vaccine score of 3.44 ± 0.91, and mean health fatalism score of 45.75 ± 17.43. Negative and significant correlations were found between participants’ mean health fatalism score and their mean p ositive attitudes score ( r = −0.213) and their mean negative attitude score ( r = −0.362) ( p < 0.001). Conclusions : Individuals were found to have high positive and low negative attitudes toward COVID-19 vaccines and moderate levels of health fatalism. Individuals with high health fatalism had low positive and high negative attitudes toward COVID-19 vaccines.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"94 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90431249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aishah Alsolami, Hanan A Alkorashy, M. Alfaki, Ahmed S Alkarani
Background : Healthcare organizations have a dynamic work-environment that changes constantly. This study aimed to explore whether there is a relationship between work-environment uncertainty and nurses’ readiness to participate in organizational change. Methods : A cross-sectional study was conducted at two tertiary hospitals. The sample size was 222 nurses. A self-report questionnaire was adopted, translated to Arabic, and used for collecting data; it consists of three scales, personal data sheet, organizational readiness for implementing change scale, and perceived environmental uncertainty in hospitals scale. Descriptive statistics t-test and analysis of variance were used to analyze the data. Results : The level of agreement with the change efficacy statements with the total mean percentage of nurses’ readiness for organizational change (change efficacy) was 67.0%, and it was slightly higher than the commitment statements, in which the total mean percentage of nurses’ readiness for organizational change (change commitment) was 64.2%. In addition, one of the work - environment uncertainty dimensions, which is the individual attribute (need for information), positively correlated with the organizational readiness to change. Conclusions : The organizational readiness to implement organizational change is high. Environmental complexity was highly perceived among nurses as one of the work-environment uncertainty dimensions. An organizational environment considering employee characteristics must be developed to improve their knowledge, skills, and attitude to adapt to change and uncertainty.
{"title":"Nurses’ Perception of Work-Environment Uncertainty and Readiness for Organizational Change","authors":"Aishah Alsolami, Hanan A Alkorashy, M. Alfaki, Ahmed S Alkarani","doi":"10.7454/msk.v27i1.1440","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1440","url":null,"abstract":"Background : Healthcare organizations have a dynamic work-environment that changes constantly. This study aimed to explore whether there is a relationship between work-environment uncertainty and nurses’ readiness to participate in organizational change. Methods : A cross-sectional study was conducted at two tertiary hospitals. The sample size was 222 nurses. A self-report questionnaire was adopted, translated to Arabic, and used for collecting data; it consists of three scales, personal data sheet, organizational readiness for implementing change scale, and perceived environmental uncertainty in hospitals scale. Descriptive statistics t-test and analysis of variance were used to analyze the data. Results : The level of agreement with the change efficacy statements with the total mean percentage of nurses’ readiness for organizational change (change efficacy) was 67.0%, and it was slightly higher than the commitment statements, in which the total mean percentage of nurses’ readiness for organizational change (change commitment) was 64.2%. In addition, one of the work - environment uncertainty dimensions, which is the individual attribute (need for information), positively correlated with the organizational readiness to change. Conclusions : The organizational readiness to implement organizational change is high. Environmental complexity was highly perceived among nurses as one of the work-environment uncertainty dimensions. An organizational environment considering employee characteristics must be developed to improve their knowledge, skills, and attitude to adapt to change and uncertainty.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74967080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akgun Yesiltepe, Bedriye Cansu Demirkiran, Sevgi Demir Çam
Background : Social media use has become an indispensable part of our lives as a result of technology advancement and is quite high among students. Methods : This study employed a cross-sectional design. Participants were 289 students from the Faculty of Health Sciences at Artvin Coruh University, Turkey. The Social Media Addiction Scale (SMAS) was used to obtain data. T-test, one-way ANOVA, Pearson’s correlation, and Bonferroni analysis were used to analyze the data. Results : The participants’ mean SMAS score was 81.03 ± 34.79, which was moderate. A weak and positive correlation was found between social media addiction and daily social media use. Statistical differences were found between social media addiction and social class, maternal education level, place of residence, income level, and general health status. Further, statistically significant differences were found between access to social media such as Facebook, Twitter, and Skype, and SMAS and subscales ( p < 0.05). Conclusions : The nursing students in this study showed moderate levels of social media addiction. Factors such as daily social media use, year of study, maternal education level, place of residence, income level, and general health status are associated with the degree of social media addiction.
背景:由于科技的进步，社交媒体的使用已经成为我们生活中不可或缺的一部分，并且在学生中使用率很高。方法:本研究采用横断面设计。参与者是来自土耳其阿尔特文·科鲁大学健康科学学院的289名学生。使用社交媒体成瘾量表(Social Media Addiction Scale, SMAS)获取数据。采用t检验、单因素方差分析、Pearson相关分析和Bonferroni分析对数据进行分析。结果:参与者的平均SMAS评分为81.03±34.79，为中等。社交媒体成瘾与日常社交媒体使用之间存在微弱的正相关关系。社交媒体成瘾与社会阶层、母亲教育水平、居住地、收入水平和一般健康状况存在统计学差异。此外，在使用社交媒体(如Facebook、Twitter和Skype)、SMAS和子量表之间发现了统计学上显著的差异(p < 0.05)。结论:本研究护生存在中等程度的社交媒体成瘾。日常社交媒体使用情况、学习年份、母亲受教育程度、居住地、收入水平、总体健康状况等因素与社交媒体成瘾程度相关。
{"title":"Social Media Addiction Among Nursing Students and Its Related Factors","authors":"Akgun Yesiltepe, Bedriye Cansu Demirkiran, Sevgi Demir Çam","doi":"10.7454/msk.v27i1.1417","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1417","url":null,"abstract":"Background : Social media use has become an indispensable part of our lives as a result of technology advancement and is quite high among students. Methods : This study employed a cross-sectional design. Participants were 289 students from the Faculty of Health Sciences at Artvin Coruh University, Turkey. The Social Media Addiction Scale (SMAS) was used to obtain data. T-test, one-way ANOVA, Pearson’s correlation, and Bonferroni analysis were used to analyze the data. Results : The participants’ mean SMAS score was 81.03 ± 34.79, which was moderate. A weak and positive correlation was found between social media addiction and daily social media use. Statistical differences were found between social media addiction and social class, maternal education level, place of residence, income level, and general health status. Further, statistically significant differences were found between access to social media such as Facebook, Twitter, and Skype, and SMAS and subscales ( p < 0.05). Conclusions : The nursing students in this study showed moderate levels of social media addiction. Factors such as daily social media use, year of study, maternal education level, place of residence, income level, and general health status are associated with the degree of social media addiction.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"62 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81111825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background : Traditional health services in Indonesia have been used increasingly over the past few years because patients nowadays are more proactive in seeking various alternative modes of self-care. This study aimed to analyze factors associated with the use of traditional health services in Indonesia. Methods : This quantitative study used a cross-sectional research design. The research data were secondary data from the 2018 Indonesian Basic Health Research. The research samples were 163,259 respondents aged >10 years and the statistical test for data analysis was multiple logistic regression. Results : The percentage of respondents who used traditional health services was 73.8%. The bivariate results in this study indicate that age, gender, employment status, educational level , residence , marital status , and access to health facilities had a significant relationship with the use of traditional health services. Conclusions : The use of traditional health services was influenced by age, gender, residence, marital status, and distance. The Indonesian government needs to consider these factors when extending the use of traditional health services.
{"title":"Factors Associated with the Use of Traditional Health Services in Indonesia: A Secondary Analysis of the Indonesian Basic Health Research","authors":"Niswatul Rifka, Haerawati Idris, I. T. R. U. Tion","doi":"10.7454/msk.v27i1.1391","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1391","url":null,"abstract":"Background : Traditional health services in Indonesia have been used increasingly over the past few years because patients nowadays are more proactive in seeking various alternative modes of self-care. This study aimed to analyze factors associated with the use of traditional health services in Indonesia. Methods : This quantitative study used a cross-sectional research design. The research data were secondary data from the 2018 Indonesian Basic Health Research. The research samples were 163,259 respondents aged >10 years and the statistical test for data analysis was multiple logistic regression. Results : The percentage of respondents who used traditional health services was 73.8%. The bivariate results in this study indicate that age, gender, employment status, educational level , residence , marital status , and access to health facilities had a significant relationship with the use of traditional health services. Conclusions : The use of traditional health services was influenced by age, gender, residence, marital status, and distance. The Indonesian government needs to consider these factors when extending the use of traditional health services.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"24 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86178745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Maturation Stages of Natural Killer Cell Differentiation Culture from Cultured and Freshly Isolated Umbilical Cord Blood Hematopoietic Stem Cells","authors":"","doi":"10.7454/msk.v27i1.1429","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1429","url":null,"abstract":"","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"49 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80821879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Awatif M. Alrasheeday, Ma. Venus Borja, Eddieson Pasay-an, Farhan F. Alshammari
Background : Nursing is highlighted among professions that value caring and is perceived as the profession’s heart and soul because of its critical role in providing and delivering high-quality patient care, especially during this coronavirus disease 2019 (COVID-19) pandemic. However, little is understood about the experiences of the frontline workers in caring for persons diagnosed with COVID-19. This study aimed to explore the experiences of nurses in caring for persons diagnosed with COVID-19 inspired by the four lived worlds of van Manen. Methods : The hermeneutic phenomenology was used in nine nurses working in hospitals of Hail region. This study employed a one-to-one interview approach using the Zoom platform, conducted between June and July 2020. Results : Nine nurses articulated their experiences in caring for patients with COVID-19. Six themes emerged within the four lifeworld such as the feeling of vulnerability to COVID-19, time of uncertainties, price of being a hero, social stigma, holistic care, and sense of belongingness. Conclusions : The feeling of vulnerability to COVID-19 infection, time of uncertainties, price of being a hero, social stigma, and sense of belongingness have been understood in the context of lifeworld existential of van Manen. Issues are articulated directly from those who experienced them. Still, revisiting the existing intervention strategies of the government and institution, including regulating negative emotions, reducing related issues, and improving quality of life, is important.
{"title":"Understanding the Experiences Lived by Nurses Caring for Patients with COVID-19: A Hermeneutic Approach","authors":"Awatif M. Alrasheeday, Ma. Venus Borja, Eddieson Pasay-an, Farhan F. Alshammari","doi":"10.7454/msk.v27i1.1401","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1401","url":null,"abstract":"Background : Nursing is highlighted among professions that value caring and is perceived as the profession’s heart and soul because of its critical role in providing and delivering high-quality patient care, especially during this coronavirus disease 2019 (COVID-19) pandemic. However, little is understood about the experiences of the frontline workers in caring for persons diagnosed with COVID-19. This study aimed to explore the experiences of nurses in caring for persons diagnosed with COVID-19 inspired by the four lived worlds of van Manen. Methods : The hermeneutic phenomenology was used in nine nurses working in hospitals of Hail region. This study employed a one-to-one interview approach using the Zoom platform, conducted between June and July 2020. Results : Nine nurses articulated their experiences in caring for patients with COVID-19. Six themes emerged within the four lifeworld such as the feeling of vulnerability to COVID-19, time of uncertainties, price of being a hero, social stigma, holistic care, and sense of belongingness. Conclusions : The feeling of vulnerability to COVID-19 infection, time of uncertainties, price of being a hero, social stigma, and sense of belongingness have been understood in the context of lifeworld existential of van Manen. Issues are articulated directly from those who experienced them. Still, revisiting the existing intervention strategies of the government and institution, including regulating negative emotions, reducing related issues, and improving quality of life, is important.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"82 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83181292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dewi Nuryana, Restu Adya Cahyani, Sukma Rahayu, N. Romadlona, Elvira Liyanto, Wira Hartiti, Maria Evi Ratnawati, Budi Utomo, R. J. Magnani, I. T. R. U. Tion
Background : The unmet need for family planning in Indonesia has been stagnant since the early 2000s in the 10% – 12% range with substantial socioeconomic and geographic disparities. This study sought to better understand the factors underlying the nonuse of contraceptives among women with an apparent need for family planning so that evidence-based corrective actions can be taken. Methods : Three sources of quantitative data were used in the study — the 2017 Indonesia Demographic Health Survey, the 2018 Village Potential Survey, and the National Population and Family Planning Board service statistics. Further insights were obtained from online focus group discussions and in-depth interviews with participants in 12 districts/cities in seven provinces. Results : The analyses indicated that health concerns, service delivery-related factors, and opposition to family planning all contribute to the unmet need for family planning in Indonesia. Importantly, the salience of these factors varied significantly across different subgroups of women and geographic areas. Conclusions : Successful efforts to reduce the unmet need for family planning are complex in that they must contend with the interplay between local sociocultural contexts, individual beliefs/aspirations/preferences, and the supply environment of family planning services. Differentiated interventions for different population subgroups and geographic areas will be needed.
{"title":"Unmet Need for Family Planning in Indonesia and Its Associated Factors","authors":"Dewi Nuryana, Restu Adya Cahyani, Sukma Rahayu, N. Romadlona, Elvira Liyanto, Wira Hartiti, Maria Evi Ratnawati, Budi Utomo, R. J. Magnani, I. T. R. U. Tion","doi":"10.7454/msk.v27i1.1403","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1403","url":null,"abstract":"Background : The unmet need for family planning in Indonesia has been stagnant since the early 2000s in the 10% – 12% range with substantial socioeconomic and geographic disparities. This study sought to better understand the factors underlying the nonuse of contraceptives among women with an apparent need for family planning so that evidence-based corrective actions can be taken. Methods : Three sources of quantitative data were used in the study — the 2017 Indonesia Demographic Health Survey, the 2018 Village Potential Survey, and the National Population and Family Planning Board service statistics. Further insights were obtained from online focus group discussions and in-depth interviews with participants in 12 districts/cities in seven provinces. Results : The analyses indicated that health concerns, service delivery-related factors, and opposition to family planning all contribute to the unmet need for family planning in Indonesia. Importantly, the salience of these factors varied significantly across different subgroups of women and geographic areas. Conclusions : Successful efforts to reduce the unmet need for family planning are complex in that they must contend with the interplay between local sociocultural contexts, individual beliefs/aspirations/preferences, and the supply environment of family planning services. Differentiated interventions for different population subgroups and geographic areas will be needed.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"77 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83326654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulellah Alsolais, Benito, Nillo Areola, Amal Alfouzan, Marie Grace, Mejia Nones, Talal Ali Alharbi
Background : Reportedly, there has been a long-standing nursing shortage in Saudi Arabia. This study explored the attitudes of undergraduate student nurses considering them to be a factor contributing to this shortage. This study also investigated the association among gender, hospital exposures, and campus enrollment concerning mental health education. Methods : Quantitative correlational analysis was used on 124 student nurses in mental health nursing. Using Point Binary, Spearman's rank and one-way ANOVA, significant determinants were correlated to the domains of mental health nursing. Results : Student nurses have a positive attitude toward mental health education. Gender is significantly related to Preparedness for Mental Health (PMH) (r = 0.193, p = 0.032) and Course Effectiveness (CE) (r = 0.202, p = 0.024). Hospital exposures are significantly correlated to PMH (r = 0.455, p = 0.000), Knowledge on Mental Health (KMH) (r = 0.423, p = 0.000), Negative Stereotypes (NS) (r = 0.514, p = 0.000), CE (r = 0.266, p = 0.003), Anxiety Surrounding Mental Illness (ASMI) (r = 0.586, p = 0.000), and Valuable Contributions (VC) (r = 0.488, p = 0.000). A correlation was noted in campus enrollment between NS (r = 0.267, p = 0.012) and ASMI (r = 0.337, p = 0.001). Conclusions : Developing a positive attitude increases the acceptance of mental health education. Gender, hospital exposure, and course introduction positively influence students' views in selecting mental health nursing as their specialization.
背景:据报道，沙特阿拉伯长期存在护士短缺问题。本研究探讨了本科生护士的态度，认为他们是造成这种短缺的一个因素。本研究亦探讨性别、医院暴露、校园招生与心理健康教育的关系。方法:对124名心理健康护理专业学生护士进行定量相关分析。采用点二元、Spearman秩和单因素方差分析，显著决定因素与心理健康护理领域相关。结果:护生对心理健康教育持积极态度。性别与心理健康准备(PMH) (r = 0.193, p = 0.032)和课程有效性(CE) (r = 0.202, p = 0.024)显著相关。医院暴露与PMH (r = 0.455, p = 0.000)、心理健康知识(KMH) (r = 0.423, p = 0.000)、负面刻板印象(NS) (r = 0.514, p = 0.000)、CE (r = 0.266, p = 0.003)、精神疾病焦虑(r = 0.586, p = 0.000)、有价值贡献(VC) (r = 0.488, p = 0.000)显著相关。NS (r = 0.267, p = 0.012)与ASMI (r = 0.337, p = 0.001)在校园入学率上存在相关性。结论:培养积极的心理态度可提高心理健康教育的接受度。性别、医院暴露程度、课程介绍对学生选择心理健康护理专业有正向影响。
{"title":"Undergraduate Student Nurses’ Attitude Toward Mental Health Education: A Cross-sectional Analysis","authors":"Abdulellah Alsolais, Benito, Nillo Areola, Amal Alfouzan, Marie Grace, Mejia Nones, Talal Ali Alharbi","doi":"10.7454/msk.v27i1.1410","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1410","url":null,"abstract":"Background : Reportedly, there has been a long-standing nursing shortage in Saudi Arabia. This study explored the attitudes of undergraduate student nurses considering them to be a factor contributing to this shortage. This study also investigated the association among gender, hospital exposures, and campus enrollment concerning mental health education. Methods : Quantitative correlational analysis was used on 124 student nurses in mental health nursing. Using Point Binary, Spearman's rank and one-way ANOVA, significant determinants were correlated to the domains of mental health nursing. Results : Student nurses have a positive attitude toward mental health education. Gender is significantly related to Preparedness for Mental Health (PMH) (r = 0.193, p = 0.032) and Course Effectiveness (CE) (r = 0.202, p = 0.024). Hospital exposures are significantly correlated to PMH (r = 0.455, p = 0.000), Knowledge on Mental Health (KMH) (r = 0.423, p = 0.000), Negative Stereotypes (NS) (r = 0.514, p = 0.000), CE (r = 0.266, p = 0.003), Anxiety Surrounding Mental Illness (ASMI) (r = 0.586, p = 0.000), and Valuable Contributions (VC) (r = 0.488, p = 0.000). A correlation was noted in campus enrollment between NS (r = 0.267, p = 0.012) and ASMI (r = 0.337, p = 0.001). Conclusions : Developing a positive attitude increases the acceptance of mental health education. Gender, hospital exposure, and course introduction positively influence students' views in selecting mental health nursing as their specialization.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"40 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88816449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Dokumacioglu, H. Iskender, A. Hayirli, G. Yenice, Kubra Asena, Terim Kapakin, Ismail Bolat, E. Kirman
Background : Acetaminophen (APAP) is the most widely used analgesic drug worldwide, but it may induce renal toxicity. Betulinic acid (BA) ameliorates the oxidative stress and inflammatory response to renal damage. The present study aimed to investigate the potential protective effects of BA treatment through an experimental kidney damage rat model administered with APAP. Methods : Sprague – Dawley male rats were randomly divided into four groups: control, BA (25 mg/kg for 15 days), APAP (1 g/kg), and APAP + BA groups. BA was administered via oral gavage at a dose of 25 mg/kg for 15 days. APAP was dissolved in hot saline and administered on the last day to produce nephrotoxicity via a single oral gavage at a dose of 1 g/kg. Kidney tissue samples were analyzed for human cartilage glycoprotein 39 (YKL-40), kidney injury molecule 1 (KIM-1), interleukin 18 (IL-18), superoxide dismutase (SOD), and malondialdehyde (MDA). Data were subjected to one-way analysis of variance and the Wilcoxon rank-sum test Results : Renal tissue YKL-40, KIM-1, IL-18, and MDA levels in the APAP group were significantly higher than those in the control group ( p < 0.05). The BA treatment completely restored renal KIM-1, YKL-40, and MDA levels and partially restored renal IL-18 and SOD levels in the rats subjected to renal damage induction ( p < 0.05). The intertubular regions of rats administered with APAP had degeneration, necrosis, and infiltration of inflammatory cells and were immunopositive for IL-1 beta and 8-hydroxy-2′ - deoxyguanosine. Conclusions : BA can be used in the prevention and replacement treatment of nephrotoxicity due to its inhibitory properties in multiple pathways and powerful antioxidant effects.
{"title":"Protective Effect of Betulinic Acid Administration on Kidney Damage in Acetaminophen-Induced Nephrotoxicity Model","authors":"E. Dokumacioglu, H. Iskender, A. Hayirli, G. Yenice, Kubra Asena, Terim Kapakin, Ismail Bolat, E. Kirman","doi":"10.7454/msk.v27i1.1438","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1438","url":null,"abstract":"Background : Acetaminophen (APAP) is the most widely used analgesic drug worldwide, but it may induce renal toxicity. Betulinic acid (BA) ameliorates the oxidative stress and inflammatory response to renal damage. The present study aimed to investigate the potential protective effects of BA treatment through an experimental kidney damage rat model administered with APAP. Methods : Sprague – Dawley male rats were randomly divided into four groups: control, BA (25 mg/kg for 15 days), APAP (1 g/kg), and APAP + BA groups. BA was administered via oral gavage at a dose of 25 mg/kg for 15 days. APAP was dissolved in hot saline and administered on the last day to produce nephrotoxicity via a single oral gavage at a dose of 1 g/kg. Kidney tissue samples were analyzed for human cartilage glycoprotein 39 (YKL-40), kidney injury molecule 1 (KIM-1), interleukin 18 (IL-18), superoxide dismutase (SOD), and malondialdehyde (MDA). Data were subjected to one-way analysis of variance and the Wilcoxon rank-sum test Results : Renal tissue YKL-40, KIM-1, IL-18, and MDA levels in the APAP group were significantly higher than those in the control group ( p < 0.05). The BA treatment completely restored renal KIM-1, YKL-40, and MDA levels and partially restored renal IL-18 and SOD levels in the rats subjected to renal damage induction ( p < 0.05). The intertubular regions of rats administered with APAP had degeneration, necrosis, and infiltration of inflammatory cells and were immunopositive for IL-1 beta and 8-hydroxy-2′ - deoxyguanosine. Conclusions : BA can be used in the prevention and replacement treatment of nephrotoxicity due to its inhibitory properties in multiple pathways and powerful antioxidant effects.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"56 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83889955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential Use of the Gel Extract of Butterfly Pea Flower as Topical Therapy to Prevent Photodamage by Downregulating TNF-α and Caspase-3 Expression Levels in UVB-Exposed Rats","authors":"","doi":"10.7454/msk.v27i1.1411","DOIUrl":"https://doi.org/10.7454/msk.v27i1.1411","url":null,"abstract":"","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"19 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87259715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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