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Mathematical Investigation of the Infection Dynamics of COVID-19 Using the Fractional Differential Quadrature Method 基于分数阶微分正交法的新型冠状病毒感染动力学数学研究
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-04 DOI: 10.3390/computation11100198
M. Mohamed, S. M. Mabrouk, A. S. Rashed
In recent times, the global community has been faced with the unprecedented challenge of the coronavirus disease (COVID-19) pandemic, which has had a profound and enduring impact on both global health and the global economy. The utilization of mathematical modeling has become an essential instrument in the characterization and understanding of the dynamics associated with infectious illnesses. In this study, the utilization of the differential quadrature method (DQM) was employed in order to anticipate the characterization of the dynamics of COVID-19 through a fractional mathematical model. Uniform and non-uniform polynomial differential quadrature methods (PDQMs) and a discrete singular convolution method (DSCDQM) were employed in the examination of the dynamics of COVID-19 in vulnerable, exposed, deceased, asymptomatic, and recovered persons. An analysis was conducted to compare the methodologies used in this study, as well as the modified Euler method, in order to highlight the superior efficiency of the DQM approach in terms of code-execution times. The results demonstrated that the fractional order significantly influenced the outcomes. As the fractional order tended towards unity, the anticipated numbers of vulnerable, exposed, deceased, asymptomatic, and recovered individuals increased. During the initial week of the inquiry, there was a substantial rise in the number of individuals who contracted COVID-19, which was primarily attributed to the disease’s high transmission rate. As a result, there was an increase in the number of individuals who recovered, in tandem with the rise in the number of infected individuals. These results highlight the importance of the fractional order in influencing the dynamics of COVID-19. The utilization of the DQM approach, characterized by its proficient code-execution durations, provided significant insights into the dynamics of COVID-19 among diverse population cohorts and enhanced our comprehension of the evolution of the pandemic. The proposed method was efficient in dealing with ordinary differential equations (ODEs), partial differential equations (PDEs), and fractional differential equations (FDEs), in either linear or nonlinear forms. In addition, the stability of the DQM and its validity were verified during the present study. Moreover, the error analysis showed that DQM has better error percentages in many applications than other relevant techniques.
近年来,国际社会面临新冠肺炎疫情带来的前所未有的挑战,对全球健康和经济产生了深刻而持久的影响。利用数学建模已经成为表征和理解与传染病相关的动力学的重要工具。本研究采用微分正交法(DQM),通过分数数学模型预测COVID-19的动态特征。采用均匀多项式和非均匀多项式微分积分法(PDQMs)和离散奇异卷积法(DSCDQM)研究新冠肺炎在易感人群、暴露人群、死亡人群、无症状人群和康复人群中的动态变化。为了突出DQM方法在代码执行时间方面的优越效率,对本研究中使用的方法以及改进的欧拉方法进行了分析比较。结果表明,分数顺序对结果有显著影响。随着分数顺序趋于统一,脆弱个体、暴露个体、死亡个体、无症状个体和康复个体的预期数量增加。在调查的最初一周,感染COVID-19的人数大幅增加,这主要是由于该疾病的高传播率。结果,随着受感染人数的增加,康复的人数也在增加。这些结果突出了分数阶在影响COVID-19动态中的重要性。DQM方法以其熟练的代码执行时间为特点,为了解COVID-19在不同人群中的动态提供了重要见解,并增强了我们对大流行演变的理解。该方法可以有效地处理线性或非线性形式的常微分方程、偏微分方程和分数阶微分方程。此外,本研究还验证了DQM的稳定性和有效性。此外,误差分析表明,DQM在许多应用中比其他相关技术具有更好的错误率。
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引用次数: 1
A General Procedure to Formulate 3D Elements for Finite Element Applications 有限元应用中三维单元的通用程序
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-03 DOI: 10.3390/computation11100197
Adnan Shahriar, Arsalan Majlesi, Arturo Montoya
This paper presents a general procedure to formulate and implement 3D elements of arbitrary order in meshes with multiple element types. This procedure includes obtaining shape functions and integration quadrature and establishing an approach for checking the generated element’s compatibility with adjacent elements’ surfaces. This procedure was implemented in Matlab, using its symbolic and graphics toolbox, and complied as a GUI interface named ShapeGen3D to provide finite element users with a tool to tailor elements according to their analysis needs. ShapeGen3D also outputs files with the element formulation needed to enable users to implement the generated elements in other programming languages or through user elements in commercial finite element software. Currently, finite element (FE) users are limited to employing element formulation available in the literature, commercial software, or existing element libraries. Thus, the developed procedure implemented in ShapeGen3D offers FEM users the possibility to employ elements beyond those readily available. The procedure was tested by generating the formulation for a brick element, a brick transition element, and higher-order hexahedron and tetrahedron elements that can be used in a spectral finite element analysis. The formulation obtained for the 20-node element was in perfect agreement with the formulation available in the literature. In addition, the results showed that the interpolation condition was met for all the generated elements, which provides confidence in the implementation of the process. Researchers and educators can use this procedure to efficiently develop and illustrate three-dimensional elements.
本文给出了在多种单元类型的网格中形成和实现任意顺序的三维单元的一般程序。该过程包括获得形状函数和积分正交,并建立了一种方法来检查生成的单元与相邻单元表面的兼容性。该程序在Matlab中使用Matlab的符号和图形工具箱实现,并编译成一个名为ShapeGen3D的GUI界面,为有限元用户提供一个根据分析需求定制元素的工具。ShapeGen3D还输出带有所需元素公式的文件,使用户能够在其他编程语言中或通过商业有限元软件中的用户元素实现生成的元素。目前,有限元(FE)用户仅限于使用文献、商业软件或现有元素库中可用的元素公式。因此,在ShapeGen3D中实现的开发程序为FEM用户提供了使用超出那些现成的元素的可能性。通过生成可用于谱有限元分析的砖单元、砖过渡单元以及高阶六面体和四面体单元的公式,对该程序进行了测试。所得的20节点单元公式与文献中的公式完全一致。结果表明,生成的各单元均满足插值条件,为该过程的实现提供了信心。研究人员和教育工作者可以使用这个程序来有效地开发和说明三维元素。
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引用次数: 0
Numerical Methodology to Reduce the Drag and Control Flow around a Cam-Shaped Cylinder Integrated with Backward Splitter Plate 带后分流板的凸轮圆柱减阻控制流场的数值方法
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-03 DOI: 10.3390/computation11100196
Sunil Chamoli, Amit Joshi, Sumit Rana, Suvanjan Bhattacharaya, Ashutosh Gupta, Siddharth Ghansela, Chinaruk Thianpong, Smith Eiamsa-ard
After publishing a research article in the year 2019, a cam-shaped cylinder was introduced, and the results expressed its ability to prevent the vortex from shedding. This makes the cam-shaped cylinder a better performer than the circular cylinder. This work is an extension of past work with the aim of further reducing drag by attaching a backward splitter plate to a cam-shaped cylinder. In an attempt to decrease drag and regulate the wake regime more efficiently than the traditional splitter plate control devices, a splitter plate flow departure control device is presented in this paper for a low Reynolds number flow range (Re = 50–200). It has been noted that when plate length increases, integral parameters like drag, lift, and Strouhal number do not change monotonically. The Strouhal number (St) increases with a drop in D2/Deq, but the average drag reduces with a rise in Re and a decrease in D2/Deq, respectively. In terms of decreased drag, the current cam-shaped cylinders attached to a rearward splitter plate have shown their superiority to other bluff bodies.
在2019年发表的一篇研究文章中,引入了一种凸轮形状的圆柱体,结果表明它具有防止涡流脱落的能力。这使得凸轮形圆柱体比圆形圆柱体性能更好。这项工作是对过去工作的延伸,目的是通过在凸轮形圆柱体上附加一个向后的分离器板来进一步减少阻力。为了比传统的分流板控制装置更有效地减小阻力和调节尾迹,本文提出了一种低雷诺数流动范围(Re = 50-200)的分流板流动偏离控制装置。当板长增加时,阻力、升力和斯特罗哈尔数等积分参数不是单调变化的。斯特罗哈尔数(St)随D2/Deq的减小而增大,但平均阻力分别随Re的增大和D2/Deq的减小而减小。在减小阻力方面,当前的凸轮圆柱体与后置分流板相连接,显示出其优于其他钝体的优势。
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引用次数: 1
A Robust Deep Learning Approach for Accurate Segmentation of Cytoplasm and Nucleus in Noisy Pap Smear Images 噪声巴氏涂片图像中细胞质和细胞核精确分割的鲁棒深度学习方法
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-03 DOI: 10.3390/computation11100195
Nahida Nazir, Abid Sarwar, Baljit Singh Saini, Rafeeya Shams
Cervical cancer poses a significant global health burden, affecting women worldwide. Timely and accurate detection is crucial for effective treatment and improved patient outcomes. The Pap smear test has long been a standard cytology screening method, enabling early cancer diagnosis. However, to enhance quantitative analysis and refine diagnostic capabilities, precise segmentation of the cervical cytoplasm and nucleus using deep learning techniques holds immense promise. This research focuses on addressing the primary challenge of achieving accurate segmentation in the presence of noisy data commonly encountered in Pap smear images. Poisson noise, a prevalent type of noise, corrupts these images, impairing the precise delineation of the cytoplasm and nucleus. Consequently, segmentation boundaries become indistinct, leading to compromised overall accuracy. To overcome these limitations, the utilization of U-Net, a deep learning architecture specifically designed for automatic segmentation, has been proposed. This approach aims to mitigate the adverse effects of Poisson noise on the digitized Pap smear slides. The evaluation of the proposed methodology involved a dataset of 110 Pap smear slides. The experimental results demonstrate that the proposed approach successfully achieves precise segmentation of the nucleus and cytoplasm in noise-free images. By preserving the boundaries of both cellular components, the method facilitates accurate feature extraction, thus contributing to improved diagnostic capabilities. Comparative analysis between noisy and noise-free images reveals the superiority of the presented approach in terms of segmentation accuracy, as measured by various metrics, including the Dice coefficient, specificity, sensitivity, and intersection over union (IoU). The findings of this study underline the potential of deep-learning-based segmentation techniques to enhance cervical cancer diagnosis and pave the way for improved quantitative analysis in this critical field of women’s health.
宫颈癌对全球妇女造成重大健康负担。及时和准确的检测对于有效治疗和改善患者预后至关重要。巴氏涂片检查长期以来一直是一种标准的细胞学筛查方法,可用于早期癌症诊断。然而,为了增强定量分析和完善诊断能力,使用深度学习技术对宫颈细胞质和细胞核进行精确分割具有巨大的前景。本研究的重点是解决在巴氏涂片图像中经常遇到的噪声数据存在的情况下实现准确分割的主要挑战。泊松噪声是一种常见的噪声,它破坏了这些图像,损害了细胞质和细胞核的精确描绘。因此,分割边界变得模糊,导致整体精度受损。为了克服这些限制,提出了一种专门为自动分割设计的深度学习架构U-Net。该方法旨在减轻泊松噪声对数字化巴氏涂片的不利影响。对拟议方法的评估涉及110个巴氏涂片的数据集。实验结果表明,该方法成功地实现了无噪声图像中细胞核和细胞质的精确分割。通过保留两个细胞成分的边界,该方法有助于准确的特征提取,从而有助于提高诊断能力。通过对有噪声和无噪声图像的对比分析,揭示了该方法在分割精度方面的优势,该方法可以通过各种指标来衡量,包括Dice系数、特异性、灵敏度和交联(IoU)。这项研究的结果强调了基于深度学习的分割技术在增强宫颈癌诊断方面的潜力,并为改进妇女健康这一关键领域的定量分析铺平了道路。
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引用次数: 0
The Influence of Crystal Anisotropy on the Characteristics of Solitary Waves in the Nonlinear Supratransmission Effect: Molecular Dynamic Modeling 晶体各向异性对非线性超传输效应中孤波特性的影响:分子动力学模型
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-02 DOI: 10.3390/computation11100193
Pavel V. Zakharov, Elena A. Korznikova, Artem A. Izosimov, Andrey S. Kochkin
This study examines the mechanism of nonlinear supratransmission (NST), which involves the transfer of disturbance to discrete media at frequencies not supported by the structure. We considered a model crystal with A3B stoichiometry. The investigation was carried out using atomistic modeling through molecular dynamics. The interatomic interaction was determined by a potential obtained through the embedded atom method, which approximates the properties of the Pt3Al crystal. The effect of NST is an important property of many discrete structures. Its existence requires the discreteness and nonlinearity of the medium, as well as the presence of a forbidden zone in its spectrum. This work focuses on the differences in the NST effect due to the anisotropy of crystallographic directions. Three planes along which the disturbance caused by NST propagated were considered: (100), (110), and (111). It was found that the intensity of the disturbance along the (100) plane is an order of magnitude lower than for more densely packed directions. Differences in the shape of solitary waves depending on the propagation direction were shown. Moreover, all waves can be described by a single equation, being a solution of the discrete variational equations of macroscopic and microscopic displacements, with different parameters, emphasizing the unified nature of the waves and the contribution of crystal anisotropy to their properties. Studying the NST phenomenon is essential due to numerous applications of the latter, such as implications in information transmission and signal processing. Understanding how disturbances propagate in discrete media could lead to advancements in communication technologies, data storage, and signal amplification where the earlier mentioned ability to describe it with analytical equations is of particular importance.
本研究探讨了非线性超传输(NST)的机制,它涉及在结构不支持的频率下将扰动传递到离散介质。我们考虑了一个具有A3B化学计量的模型晶体。通过分子动力学的原子模型进行了研究。原子间的相互作用由嵌入原子法得到的电位确定,该电位近似于Pt3Al晶体的性质。NST效应是许多离散结构的一个重要性质。它的存在需要介质的离散性和非线性,以及在其光谱中存在一个禁区。本文主要研究了由于晶体方向各向异性导致的NST效应的差异。考虑由NST引起的扰动沿三个平面传播:(100)、(110)和(111)。研究发现,沿(100)平面的扰动强度比密度更大的方向低一个数量级。结果表明,随着传播方向的不同,孤立波的形状也不同。此外,所有的波都可以用一个方程来描述,它是宏观和微观位移的离散变分方程的解,具有不同的参数,强调了波的统一性和晶体各向异性对其性质的贡献。由于NST在信息传输和信号处理等诸多领域的应用,研究NST现象是必不可少的。了解干扰如何在离散介质中传播可以导致通信技术,数据存储和信号放大的进步,其中前面提到的用解析方程描述它的能力是特别重要的。
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引用次数: 1
Computational “Accompaniment” of the Introduction of New Mathematical Concepts 新数学概念引入的计算“伴奏”
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-02 DOI: 10.3390/computation11100194
Andrey Lavrenov, Elena Tolkacheva, Sergei Pozdniakov
The computational capabilities of computer tools expand the student’s search capabilities. Conducting computational experiments in the classroom is no longer an organizational problem. This raises the “black box” problem, when the student perceives the computational module as a magician’s box and loses conceptual control over the computational process. This article analyses the use of various computer tools, both existing and specially created for “key” computational experiments, that aim at revealing the essential aspects of the introduced concepts using specific examples. This article deals with a number of topics of algebra and calculus that are transitional from school to university, and it shows how computational experiments in the form of a “transparent” box can be used.
计算机工具的计算能力扩展了学生的搜索能力。在课堂上进行计算实验不再是一个组织问题。这就提出了“黑盒子”问题,当学生将计算模块视为魔术师的盒子,并失去对计算过程的概念控制时。本文分析了各种计算机工具的使用,既有现有的,也有专门为“关键”计算实验创建的,旨在通过具体的例子揭示所介绍概念的基本方面。本文讨论了从中学过渡到大学的代数和微积分的一些主题,并展示了如何使用“透明”框形式的计算实验。
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引用次数: 0
Optimization and Prediction of Different Building Forms for Thermal Energy Performance in the Hot Climate of Cairo Using Genetic Algorithm and Machine Learning 基于遗传算法和机器学习的开罗炎热气候下不同建筑形式热能性能优化与预测
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-02 DOI: 10.3390/computation11100192
Amany Khalil, Anas M. Hosney Lila, Nouran Ashraf
The climate change crisis has resulted in the need to use sustainable methods in architectural design, including building form and orientation decisions that can save a significant amount of energy consumed by a building. Several previous studies have optimized building form and envelope for energy performance, but the isolated effect of varieties of possible architectural forms for a specific climate has not been fully investigated. This paper proposes four novel office building form generation methods (the polygon that varies between pentagon and decagon; the pixels that are complex cubic forms; the letters including H, L, U, T; cross and complex cubic forms; and the round family including circular and oval forms) and evaluates their annual thermal energy use intensity (EUI) for Cairo (hot climate). Results demonstrated the applicability of the proposed methods in enhancing the energy performance of the new forms in comparison to the base case. The results of the optimizations are compared together, and the four families are discussed in reference to their different architectural aspects and performance. Scatterplots are developed for the round family (highest performance) to test the impact of each dynamic parameter on EUI. The round family optimization process takes a noticeably high calculation time in comparison to other families. Therefore, an Artificial Neural Network (ANN) prediction model is developed for the round family after simulating 1726 iterations. Training of 1200 configurations is used to predict annual EUI for the remaining 526 iterations. The ANN predicted values are compared against the trained to determine the time saved and accuracy.
气候变化危机导致在建筑设计中需要使用可持续的方法,包括建筑形式和朝向的决定,这可以节省建筑消耗的大量能源。以前的一些研究已经优化了建筑形式和围护结构的能源性能,但各种可能的建筑形式对特定气候的孤立影响尚未得到充分调查。本文提出了四种新的办公楼形态生成方法(五边形和十角形之间变化的多边形;像素是复杂的立方形式;字母包括H、L、U、T;交叉和复杂的立方体;以及圆形家庭(包括圆形和椭圆形),并评估其在开罗(炎热气候)的年度热能利用强度(EUI)。结果表明,与基本情况相比,所提出的方法在提高新形式的能源性能方面具有适用性。将优化的结果放在一起进行比较,并根据其不同的体系结构方面和性能讨论这四个系列。为圆族(最高性能)开发了散点图,以测试每个动态参数对EUI的影响。与其他族相比,圆族优化过程的计算时间明显较高。为此,在模拟了1726次迭代后,建立了圆形族的人工神经网络(ANN)预测模型。1200个配置的训练用于预测剩余526个迭代的年度EUI。将人工神经网络预测值与训练值进行比较,以确定节省的时间和准确性。
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引用次数: 0
Fuzzy Transform Image Compression in the YUV Space YUV空间中的模糊变换图像压缩
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-10-01 DOI: 10.3390/computation11100191
Barbara Cardone, Ferdinando Di Martino, Salvatore Sessa
This research proposes a new image compression method based on the F1-transform which improves the quality of the reconstructed image without increasing the coding/decoding CPU time. The advantage of compressing color images in the YUV space is due to the fact that while the three bands Red, Green and Blue are equally perceived by the human eye, in YUV space most of the image information perceived by the human eye is contained in the Y band, as opposed to the U and V bands. Using this advantage, we construct a new color image compression algorithm based on F1-transform in which the image compression is accomplished in the YUV space, so that better-quality compressed images can be obtained without increasing the execution time. The results of tests performed on a set of color images show that our color image compression method improves the quality of the decoded images with respect to the image compression algorithms JPEG, F1-transform on the RGB color space and F-transform on the YUV color space, regardless of the selected compression rate and with comparable CPU times.
本研究提出了一种新的基于f1变换的图像压缩方法,在不增加编码/解码CPU时间的前提下,提高了重构图像的质量。在YUV空间压缩彩色图像的优势在于人眼可以同样感知红、绿、蓝三个波段,而人眼感知到的大部分图像信息在YUV空间中包含在Y波段,而不是U和V波段。利用这一优势,我们构建了一种新的基于f1变换的彩色图像压缩算法,该算法在YUV空间完成图像压缩,在不增加执行时间的情况下获得质量更好的压缩图像。在一组彩色图像上进行的测试结果表明,无论所选择的压缩率如何,在CPU时间相当的情况下,与图像压缩算法JPEG、RGB颜色空间的f1变换和YUV颜色空间的f变换相比,我们的彩色图像压缩方法提高了解码图像的质量。
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引用次数: 0
Graph-Theoretical Analysis of Biological Networks: A Survey 生物网络的图论分析综述
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-30 DOI: 10.3390/computation11100188
Kayhan Erciyes
Biological networks such as protein interaction networks, gene regulation networks, and metabolic pathways are examples of complex networks that are large graphs with small-world and scale-free properties. An analysis of these networks has a profound effect on our understanding the origins of life, health, and the disease states of organisms, and it allows for the diagnosis of diseases to aid in the search for remedial processes. In this review, we describe the main analysis methods of biological networks using graph theory, by first defining the main parameters, such as clustering coefficient, modularity, and centrality. We then survey fundamental graph clustering methods and algorithms, followed by the network motif search algorithms, with the aim of finding repeating subgraphs in a biological network graph. A frequently appearing subgraph usually conveys a basic function that is carried out by that small network, and discovering such a function provides an insight into the overall function of the organism. Lastly, we review network alignment algorithms that find similarities between two or more graphs representing biological networks. A conserved subgraph between the biological networks of organisms may mean a common ancestor, and finding such a relationship may help researchers to derive ancestral relationships and to predict the future evolution of organisms to enable the design of new drugs. We provide a review of the research studies in all of these methods, and conclude using the current challenging areas of biological network analysis, and by using graph theory and parallel processing for high performance analysis.
生物网络,如蛋白质相互作用网络、基因调控网络和代谢途径,是具有小世界和无标度特性的大图复杂网络的例子。对这些网络的分析对我们理解生命、健康和生物体的疾病状态的起源有着深远的影响,它允许疾病的诊断,以帮助寻找治疗过程。在这篇综述中,我们首先定义了聚类系数、模块化和中心性等主要参数,描述了利用图论分析生物网络的主要方法。然后,我们研究了基本的图聚类方法和算法,然后是网络基序搜索算法,目的是在生物网络图中找到重复的子图。一个频繁出现的子图通常传达了一个由这个小网络执行的基本功能,发现这样一个功能提供了对有机体整体功能的洞察。最后,我们回顾了网络对齐算法,发现两个或多个表示生物网络的图之间的相似性。生物网络之间的保守子图可能意味着一个共同的祖先,发现这样的关系可能有助于研究人员推导祖先关系,并预测生物的未来进化,从而设计新药。我们对所有这些方法的研究进行了回顾,并总结了当前生物网络分析中具有挑战性的领域,以及使用图论和并行处理进行高性能分析。
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引用次数: 0
Two-Dimensional Uniform and Non-Uniform Haar Wavelet Collocation Approach for a Class of Nonlinear PDEs 一类非线性偏微分方程的二维均匀与非均匀Haar小波配置方法
Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Pub Date : 2023-09-30 DOI: 10.3390/computation11100189
Narendra Kumar, Amit K. Verma, Ravi P. Agarwal
In this paper, we introduce a novel approach employing two-dimensional uniform and non-uniform Haar wavelet collocation methods to effectively solve the generalized Burgers–Huxley and Burgers–Fisher equations. The demonstrated method exhibits an impressive quartic convergence rate. Several test problems are presented to exemplify the accuracy and efficiency of this proposed approach. Our results exhibit exceptional accuracy even with a minimal number of spatial divisions. Additionally, we conduct a comparative analysis of our results with existing methods.
本文提出了一种利用二维均匀和非均匀Haar小波配置方法有效求解广义burger - huxley方程和burger - fisher方程的新方法。所证明的方法具有令人印象深刻的四次收敛速度。通过几个测试问题验证了该方法的准确性和有效性。我们的结果即使在最小数量的空间划分下也表现出卓越的准确性。此外,我们将我们的结果与现有方法进行比较分析。
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引用次数: 0
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Computation
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