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Foreword to the Special Issue on the 7th International Conference on Nanomanufacturing (nanoMan2021) 第七届纳米制造国际会议专刊(nanoMan2021)前言
Q1 Engineering Pub Date : 2022-11-10 DOI: 10.1007/s41871-022-00176-0
Shuming Yang, Zhuangde Jiang
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引用次数: 0
Impact of Pulsed Laser Parameters and Scanning Pattern on the Properties of Thin-Walled Parts Manufactured Using Laser Metal Deposition 脉冲激光参数和扫描方式对激光金属沉积薄壁件性能的影响
Q1 Engineering Pub Date : 2022-11-02 DOI: 10.1007/s41871-022-00175-1
Weiwei Liu, Gamal Al-Hammadi, Kazi Mojtaba Saleheen, A. Abdelrahman, Huanqiang Liu, Zhidong Zhang
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引用次数: 3
A Review on Metasurface Beam Splitters 超表面分束器研究进展
Q1 Engineering Pub Date : 2022-11-01 DOI: 10.3390/nanomanufacturing2040014
Zhe Shen, Dingxin Huang
Beam splitters are widely used in various optical systems, but traditional beam splitters are bulky and heavy, which are not conducive to the integrated utilization of optical devices. Metamaterials have attracted extensive attention as a kind of miniature artificial materials, and there have been many works on the design of metasurface beam splitters. Using metasurfaces, multiple functions of traditional beam splitters can be achieved. Meanwhile, metasurface beam splitters have the advantages of small size, easy integration, flexible design of beam-splitting performance, and tunable functions. This review surveys the current work on metasurface beam splitters and provides a classification and introduction to metasurface beam splitters. Metasurface beam splitters are expected to play a huge role in interferometers, multiplexing, multi-beam communications, and more.
分束器广泛应用于各种光学系统中,但传统的分束器体积大、重量大,不利于光学器件的综合利用。超材料作为一种微型人工材料受到了广泛的关注,超表面分束器的设计也有很多工作。利用超表面,可以实现传统分束器的多种功能。同时,超表面分束器具有体积小、易于集成、分束性能设计灵活、功能可调等优点。本文综述了超表面分束器的研究现状,并对超表面分束器进行了分类和介绍。超表面分束器有望在干涉仪、多路复用、多波束通信等领域发挥巨大作用。
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引用次数: 6
Adaptive Thermoforming and Structural Design of Millimeter-Wave Antenna Panels 毫米波天线面板的自适应热成形与结构设计
Q1 Engineering Pub Date : 2022-10-23 DOI: 10.1007/s41871-022-00169-z
Zack Hatfield, A. S. Peter, C. Dávila-Peralta, Joel Berkson, Daewook Kim, J. Hyatt
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引用次数: 0
Magnesium Sublimation for Growing Thin Films and Conformal Coatings on 1D Nanostructures 镁升华法在一维纳米结构上生长薄膜和适形涂层
Q1 Engineering Pub Date : 2022-10-10 DOI: 10.3390/nanomanufacturing2040013
Aaron J. Austin, Nate Dice, E. Echeverria, A. Gupta, Jonathan Risner, Halle C. Helfrich, R. Sachan, D. Mcilroy
A method to conformally coat silica nanosprings with magnesium via sublimation at 450oC has been developed. In addition, Mg thin films were grown on Si(100) using this method to determine the effects of substrate morphology (nanoscale curvatures vs. planar) on the interfacial morphology of the Mg coating. High-resolution/powder X-ray diffraction (HRXRD/PXRD) on both the Mg-coated NS and the thin film revealed the presence of Mgand MgO due to exposure of the samples to air. Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) confirmed the presence of Mg on the nanosprings. Elemental mapping with TEM-EDS verified that Mg uniformity and conformally coats the nanosprings. Nanocrystallinity of the Mg coating on the nanosprings was determined to be polycrystalline by TEM and selected area electron diffraction (SAED). In contrast, the process produces large micron-scale crystals on planar surfaces.
提出了一种在450℃下用镁升华法制备二氧化硅纳米弹簧的方法。此外,使用该方法在Si(100)上生长Mg薄膜,以确定衬底形态(纳米级曲率与平面)对Mg涂层界面形态的影响。高分辨率/粉末x射线衍射(HRXRD/PXRD)显示,由于样品暴露于空气中,镁包覆的NS和薄膜都存在镁和MgO。扫描电镜(SEM)和能谱分析(EDS)证实了纳米弹簧上存在Mg。TEM-EDS元素映射验证了Mg均匀性和共形包裹纳米弹簧。通过透射电镜和选择面积电子衍射(SAED)测定了纳米弹簧表面Mg涂层的纳米结晶度为多晶。相比之下,该工艺在平面表面上产生大的微米级晶体。
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引用次数: 1
Correction of Interferometric High-Order Nonlinearity Error in Metrological Atomic Force Microscopy 计量原子力显微镜干涉高阶非线性误差的校正
Q1 Engineering Pub Date : 2022-10-06 DOI: 10.1007/s41871-022-00154-6
G. Dai, Xiukun Hu
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引用次数: 6
Anti-Inflammatory Nanocarriers Based on SWCNTs and Bioactive Molecules of Oregano: An In Silico Study 基于SWCNTs和牛至生物活性分子的抗炎纳米载体:一项硅研究
Q1 Engineering Pub Date : 2022-10-02 DOI: 10.3390/nanomanufacturing2040012
E. Díaz-Cervantes, Alejandra Monjaraz-Rodríguez, F. Aguilera-Granja
We studied two main bioactive molecules of oregano, carvacrol and thymol, in the present work. These bioactive conformers are linked to single wall carbon nanotubes (SWCNT) and so-called functionalized SWCNT (f-SWCNT) to find their application as anti-inflammatory drugs. We use the multiscale methods and the density functional theory (DFT) of formalism to achieve this aim. We have proposed two nanocarriers based on a finite size model of a metallic single wall carbon nanotube linked to carvacrol and thymol (with a size around 2.74 nm): the main bioactives present in oregano. The results show that the proposed molecules, Carva-SWCNT-Gluc and Thymol-SWCNT-Gluc, can be synthesized with the exposed condensation reaction; with an exergonic and spontaneous behavior, Gibbs free energies of the reaction are −1.75 eV and −1.81 eV, respectively. The studied molecules are subjected to an electronic characterization, considering the global descriptors based on the conceptual DFT formalism. Moreover, the results show that the studied molecules can present a possible biocompatibility due to the higher polarization of the molecule and the increase in apparent solubility. Finally, the interaction between the studied nanodevices (Carva-SWCNT-Gluc and Thymol-SWCNT-Gluc) with cancer and anti-inflammatory targets shows that the hydrogen bond and electrostatic interactions play a crucial role in the ligand–target interaction. The proposed f-SWCNT presents higher potentiality as a carrier vector nanodevice since it can deliver the oregano bioactives on the studied targets, promoting the putative apoptosis of neoplastic cells and simultaneously regulating the inflammatory process.
本文研究了牛至叶中两种主要的生物活性分子——香芹酚和百里香酚。这些生物活性构象与单壁碳纳米管(SWCNT)和所谓的功能化SWCNT (f-SWCNT)相连接,以寻找它们作为抗炎药物的应用。我们使用多尺度方法和形式主义的密度泛函理论(DFT)来实现这一目标。我们基于金属单壁碳纳米管的有限尺寸模型提出了两种纳米载体,碳纳米管连接着香芹酚和百里香酚(尺寸约2.74 nm):牛至叶中存在的主要生物活性物质。结果表明,Carva-SWCNT-Gluc和thymoll - swcnt - gluc可以通过暴露的缩合反应合成;反应的吉布斯自由能分别为- 1.75 eV和- 1.81 eV。考虑基于概念DFT形式的全局描述符,研究分子受到电子表征。此外,研究结果表明,由于分子具有较高的极化和表观溶解度的增加,所研究的分子可能具有生物相容性。最后,研究的纳米器件(carva - swcnts - gluc和thymoll - swcnts - gluc)与抗癌和抗炎靶标的相互作用表明,氢键和静电相互作用在配体-靶标相互作用中起着至关重要的作用。所提出的f-SWCNT作为载体纳米器件具有更高的潜力,因为它可以将牛至植物的生物活性物质递送到研究的靶标上,促进肿瘤细胞的凋亡,同时调节炎症过程。
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引用次数: 0
Advanced Fabrication of miRNA-Based Electrochemical Nanobiosensor for Diagnosis of Breast Cancer 基于mirna的乳腺癌诊断电化学纳米传感器的先进制造
Q1 Engineering Pub Date : 2022-09-07 DOI: 10.3390/nanomanufacturing2030011
C. I. Kuru, S. Akgöl
Early diagnosis is the key to easy, low cost, and effective treatment of breast cancer. Therefore, studies have been accelerated to identify breast cancer diagnostic biomarkers and diagnose cancer before it progresses. The use of miR-155 as a potential biomarker in breast cancer, which has different levels at different stages of the disease, provides a simple serological test for breast cancer prognosis/diagnosis, follow-up, and treatment. Nanopolymers containing different functional groups that are formed by thiol affinity technique were synthesized by mini emulsion polymerization method and advanced characterization studies were carried out in this study to be used as bioactive layers in the nanobiosensor system for miRNA detection. The working conditions of the electrochemical nanobiosensor in which nanopolymers are used as bioactive layers were optimized. Analytical measurement characteristics and validation studies of the nanobiosensor were determined and analysis was performed on commercial blood serum. The potential of the developed electrochemical biosensor to be used as a medical diagnostic kit was explained by comparing it with commercial miRNA kit currently used for the detection of miR-155. This novel nanobiosensor provide sensitive, reliable, and rapid detection of miR-155 and it can provide the potential for breast cancer early diagnosis, prognosis, and follow-up.
早期诊断是简单、低成本、有效治疗乳腺癌的关键。因此,加快了识别乳腺癌诊断生物标志物和在癌症发展之前进行诊断的研究。miR-155作为乳腺癌的潜在生物标志物,在疾病的不同阶段具有不同的水平,为乳腺癌的预后/诊断、随访和治疗提供了一种简单的血清学检测。采用微乳液聚合的方法合成了巯基亲和技术形成的含不同官能团的纳米聚合物,并对其进行了深入的表征研究,作为纳米生物传感器系统中检测miRNA的生物活性层。优化了以纳米聚合物为生物活性层的电化学纳米生物传感器的工作条件。确定了纳米生物传感器的分析测量特性和验证研究,并在商品血清上进行了分析。通过将所开发的电化学生物传感器与目前用于检测miR-155的商用miRNA试剂盒进行比较,解释了其作为医疗诊断试剂盒的潜力。这种新型纳米生物传感器可以灵敏、可靠、快速地检测miR-155,为乳腺癌的早期诊断、预后和随访提供可能。
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引用次数: 0
Adsorption of Selected Molecules on (TiO2)20 Nano-Clusters: A Density-Functional-Theory Study 选择性分子在(TiO2)20纳米团簇上的吸附:密度泛函理论研究
Q1 Engineering Pub Date : 2022-09-01 DOI: 10.3390/nanomanufacturing2030010
F. Aguilera-Granja, R. Aguilera-del-Toro, E. Díaz-Cervantes
In this work, the adsorption energies and some of the main electronic properties of selected biological molecules adsorbed onto a (TiO2)20 cluster were studied. With this aim, Density-Functional Theory (DFT) calculations were performed using SIESTA code. The Perdew–Burke–Ernzerhof (PBE) functional within the Generalized Gradient Approximation (GGA) was used for the exchange and correlation potential. For this study, we chose molecules with very different characteristics and applications in everyday life, including antibiotics, anti-inflammatory drugs, vitamins, and so on. The TiO2 substrate was considered due to its harmlessness and versatility of application in various industries. In particular, we studied the changes in some of the main electronic properties of the molecules after adsorption onto titanium dioxide. For all of the molecules studied here, we observed that this substrate can increase the stability of the adsorbed molecules, with values in the range of 12–150 meV/atom. The reliability of our calculations was verified through additional optimizations with other DFT codes, considering the hybrid functionals B3LYP and M06-L. Our results showed a reasonably good agreement among these three functionals, thereby revealing the possibility of adsorption of the selected biological molecules onto the vertex of the TiO2 nanoclusters. Some of these molecules were considered as possible candidates for the delivery of drugs into the SARS-CoV-2 main protease, promoting the inhibition of this virus. We are not aware of any systematic study that has focused on the adsorption of the selected molecules on a (TiO2)20 substrate within the same framework, including the analysis of the differences in electronic properties through the use of different functionals.
在这项工作中,研究了选择的生物分子吸附在(TiO2)20簇上的吸附能和一些主要的电子性质。为此,使用SIESTA代码进行了密度泛函理论(DFT)计算。利用广义梯度近似(GGA)中的Perdew-Burke-Ernzerhof (PBE)泛函表示交换电位和相关电位。在这项研究中,我们选择了在日常生活中具有非常不同特性和应用的分子,包括抗生素、抗炎药、维生素等。二氧化钛衬底被认为是由于其无害和多用途的应用在各个行业。特别地,我们研究了分子在二氧化钛上吸附后的一些主要电子性质的变化。对于这里研究的所有分子,我们观察到该底物可以增加吸附分子的稳定性,其值在12-150 meV/原子范围内。考虑到混合函数B3LYP和M06-L,通过使用其他DFT代码进行额外优化,验证了我们计算的可靠性。我们的研究结果表明,这三个官能团之间具有相当好的一致性,从而揭示了所选择的生物分子在TiO2纳米簇的顶点上吸附的可能性。其中一些分子被认为是将药物输送到SARS-CoV-2主要蛋白酶中,促进对该病毒的抑制的可能候选者。我们不知道有任何系统的研究集中在相同框架内(TiO2)20衬底上所选分子的吸附,包括通过使用不同的功能分析电子性质的差异。
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引用次数: 5
Surface Nanopatterning Using the Self-Assembly of Linear Polymers on Surfaces after Solvent Evaporation 利用溶剂蒸发后线性聚合物在表面自组装的表面纳米图形
Q1 Engineering Pub Date : 2022-09-01 DOI: 10.1007/s41871-022-00152-8
E. Glynos, Alexandros Chremos, P. Camp, V. Koutsos
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引用次数: 3
期刊
Nanomanufacturing and Metrology
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