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Treatment of SSNHL in the COVID-19 pandemic – time for changes 在COVID-19大流行中治疗SSNHL -时间的变化
Q4 Medicine Pub Date : 2022-06-01 DOI: 10.5604/01.3001.0015.8663
W. Narożny, J. Kot, A. Skorek, D. Tretiakow
Our work aimed to review the literature about sudden sensorineural hearing loss (SSNHL) treatment and the approach to this problem during the COVID-19 pandemic. Current knowledge on SSNHL was sought and presented based on literature published in English-language journals from the Master Journal List. We searched for articles in the MEDLINE, PubMed, and Scopus databases. Sudden sensorineural hearing loss (SSNHL) is a relatively common pathology in otolaryngology. The American Academy of Otolaryngology-Head and Neck Surgery published guidelines for managing SSNHL, specifying systemic and intratympanic (IT) steroid therapy and hyperbaric oxygen therapy (HBOT) as the optional adjunctive treatment. However, due to the COVID-19 pandemic, the standard treatment of SSNHL needed to be verified to identify possible interference of virus infection with pharmacological and hyperbaric therapy. The general use of standard treatment of SSNHL with steroids and HBO according to internationally approved guidelines should ensure safe medical procedures due to epidemiological restrictions. Potential relations between COVID-19 and SSNHL, as well as concomitant use of anticoagulants, should be investigated.
我们的工作旨在回顾有关COVID-19大流行期间突发性感音神经性听力损失(SSNHL)治疗的文献及其方法。目前关于SSNHL的知识是根据Master Journal List中发表在英语期刊上的文献进行检索和呈现的。我们在MEDLINE、PubMed和Scopus数据库中搜索文章。突发性感音神经性听力损失(SSNHL)是耳鼻喉科较为常见的病理。美国耳鼻喉头颈外科学会发布了SSNHL治疗指南,指定全身和腔内(IT)类固醇治疗和高压氧治疗(HBOT)作为可选的辅助治疗。然而,由于COVID-19大流行,SSNHL的标准治疗需要验证,以确定药物和高压氧治疗可能对病毒感染的干扰。由于流行病学的限制,根据国际批准的指南,一般使用类固醇和HBO对SSNHL进行标准治疗,应确保医疗程序的安全。应调查COVID-19与SSNHL之间的潜在关系,以及抗凝剂的联合使用。
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引用次数: 0
Multi-level comparison of congenital and acquired anosmia 先天性和后天性嗅觉缺失的多层次比较
Q4 Medicine Pub Date : 2022-05-31 DOI: 10.5604/01.3001.0015.8948
Aleksandra Romanowicz, K. Kwaśniewski, W. Brzoznowski, D. Tretiakow, Ł. Plichta, A. Skorek
Introduction: Anosmia is the loss of the ability to detect one or more smells which can affect 3–20% of the population. The disorder divides into two types: congenital and acquired. Aim: The objective of the study is to demonstrate the differences in social adaptation, quality of life and clinical features between patients with congenital and acquired anosmia. Material and methods: Survey that contained questions about the quality of life, taste disorders, genesis of anosmia, perception from the trigeminal nerve, etc. was provided at the beginning of the COVID-19 pandemic thus the vast majority of patients did not suffer from COVID-19 at that time. People affected by hyposmia were removed from our research. A level of P < 0.05 was used to determine statistical significance. Results: A total of 331 patients completed the survey. Patients with acquired anosmia rated their quality of life lower than patients with congenital anosmia in EQ-VAS. As many as 44.6% of people with acquired anosmia claimed that their quality of life decreased mainly in the aspect of feeling pleasure, whereas 40.7% of people with congenital anosmia claimed that none of the aspects of their life decreased. Taste disorders rarely occur in the group of people with congenital anosmia in comparison to the group of people with acquired anosmia (11.5% vs 38.7%). Trigeminal nerve dysfunction two times more often accompanies acquired anosmia than congenital anosmia. Conclusion: People with acquired anosmia tolerate anosmia worse than people with congenital anosmia. Congenital anosmia significantly differs from acquired anosmia. More research in the field of anosmia needs to be conducted.
简介:嗅觉缺失症是一种丧失检测一种或多种气味能力的疾病,影响3-20%的人群。这种疾病分为先天性和后天两种类型。目的:研究先天性和获得性嗅觉缺失患者在社会适应、生活质量和临床特征方面的差异。材料和方法:在新冠肺炎大流行之初就进行了调查,调查内容包括生活质量、味觉障碍、嗅觉缺失的发生、三叉神经感知等问题,绝大多数患者当时并未患新冠肺炎。受低体温影响的人被排除在我们的研究之外。以P < 0.05为差异有统计学意义。结果:共331例患者完成调查。在EQ-VAS中,获得性嗅觉缺失患者对生活质量的评价低于先天性嗅觉缺失患者。高达44.6%的获得性嗅觉缺失患者声称他们的生活质量主要在感觉愉悦方面下降,而40.7%的先天性嗅觉缺失患者声称他们的生活质量在任何方面都没有下降。与获得性嗅觉缺失患者相比,先天性嗅觉缺失患者很少发生味觉障碍(11.5% vs 38.7%)。三叉神经功能障碍伴随获得性嗅觉障碍的发生率是先天性嗅觉障碍的两倍。结论:获得性嗅觉障碍患者对嗅觉障碍的耐受性较先天性嗅觉障碍患者差。先天性嗅觉缺失与后天性嗅觉缺失有显著差异。嗅觉缺失领域还需要进行更多的研究。
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引用次数: 0
Surgery for Epiglottic Collapse in OSA Patients OSA患者声门上塌陷的外科治疗
Q4 Medicine Pub Date : 2022-05-08 DOI: 10.5604/01.3001.0015.8252
Ido Amir, Hanna Gilat, U. Alkan
Obstructive sleep apnea (OSA) is a common clinical entity, impacting millions of people worldwide. This condition stems from abnormal anatomical and physiological features, leading to intermittent upper airway collapse during sleeping hours. It has been well established that patients suffering from OSA are at increased risk for adverse cardiovascular outcomes if not properly diagnosed and treated in time. Aside from non-invasive treatments, such as positive airway pressure (PAP) masks, several surgical modalities have been shown to successfully reduce the severity and frequency of upper airway collapse. However, because different pathological mechanisms play a role in the pathophysiology of each patient’s condition, a more individualized approach is needed. One such mechanism is epiglottic collapse, which has been yet to be adequately studied and understood. Furthermore, the volume of medical literature addressing the role of epiglottic collapse in OSA and its association with different treatment outcomes is scarce. In this review of the literature, our aim was to present the current existing knowledge regarding epiglottic collapse, its role in the pathophysiology of OSA and the management of OSA associated with epiglottic collapse. We conclude that further research is needed in order to formulate quality evidence-based clinical guidelines regarding the issue at hand.
阻塞性睡眠呼吸暂停(OSA)是一种常见的临床疾病,影响着全球数百万人。这种情况源于异常的解剖和生理特征,导致睡眠时间内上呼吸道间歇性塌陷。众所周知,如果不能及时正确诊断和治疗,OSA患者发生不良心血管后果的风险会增加。除了非侵入性治疗,如气道正压通气(PAP)面罩,几种手术方式已被证明可以成功降低上呼吸道塌陷的严重程度和频率。然而,由于不同的病理机制在每个患者病情的病理生理学中发挥作用,因此需要一种更个性化的方法。会厌塌陷是其中一种机制,目前尚待充分研究和理解。此外,关于会厌塌陷在OSA中的作用及其与不同治疗结果的关系的医学文献数量很少。在这篇文献综述中,我们的目的是介绍目前关于会厌塌陷的现有知识,它在OSA的病理生理学中的作用,以及与会厌塌陷相关的OSA的治疗。我们的结论是,需要进一步的研究,以制定关于当前问题的高质量循证临床指南。
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引用次数: 0
Effect of disease duration on the distribution of otosclerotic foci within the stapes based on scanning electron microscopy analysis 基于扫描电镜分析的病程对镫骨内耳硬核灶分布的影响
Q4 Medicine Pub Date : 2022-04-08 DOI: 10.5604/01.3001.0015.8211
M. Wiatr, R. Bartoszewicz, K. Niemczyk, Kamila Szpak, A. Wiatr
Introduction: Otosclerosis is characterized by the presence of abnormal resorption and recalcification of the endochondral layer of the temporal bone, which is not observed in healthy subjects. The result of the alternating occurrence of both processes is the appearance of disorganized and, over time, dense, sclerotic bone tissue underlying the clinical manifestation of the otosclerotic process.Aim: The aim of the work is the chemical analysis of otosclerotic foci of the stapes superstructure with the use of a scanning electron microscope.Material and methods: Patients operated for the first time due to otosclerosis were analyzed. The removed stirrup suprastructures were examined in a Scanning Electron Microscope (SEM) using microanalytical techniques (WDXS – Wavelength-dispersive X-ray spectroscopy TEXS – Transition Element X-ray Spectrometer) and diffraction techniques (2D EBSD – Electron Backscatter Diffraction).Results: In patients with a short medical history, a statistically significant difference in calcium (Ca) concentration was found between the anterior and posterior cruses of stapes. Along with the duration of the disease, a statistically significant difference in calcium (Ca) concentration was observed between the stapes head and its cruses. In the course of the disease, degradation of the microstructure of the stapes bone tissue was observed in a scanning electron microscope.Conclusions: (A) As the otosclerotic process progresses, significant changes in the chemical composition between the individual parts of the stapes superstructure are observed; (B) The observed biochemical changes are accompanied by changes in the microstructure of bone tissue observed in SEM.
引言:耳硬症的特点是颞骨软骨内层出现异常吸收和再钙化,这在健康受试者中是没有观察到的。这两个过程交替发生的结果是,随着时间的推移,出现紊乱且致密的硬化骨组织,这是耳硬核过程临床表现的基础。目的:利用扫描电子显微镜对镫骨上部结构的耳核灶进行化学分析。材料与方法:对因耳硬化症首次手术的患者进行分析。在扫描电子显微镜(SEM)中使用微量分析技术(WDXS–波长色散X射线光谱TEXS–过渡元素X射线光谱仪)和衍射技术(2D EBSD–电子背散射衍射)对去除的镫形超结构进行检查。结果:在病史较短的患者中,镫骨前后脚之间的钙(Ca)浓度存在统计学显著差异。随着疾病的持续时间,在镫骨头和镫骨脚之间观察到钙(Ca)浓度的统计学显著差异。在疾病过程中,扫描电子显微镜观察到镫骨组织的微观结构退化。结论:(A)随着耳硬化过程的进展,镫骨上部结构各部分之间的化学成分发生了显著变化;(B) 观察到的生物化学变化伴随着在SEM中观察到的骨组织微观结构的变化。
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引用次数: 0
Interleukin-5 Levels in Chronic Rhinosinusitis Patients With and Without Allergy 慢性鼻窦炎伴和非过敏患者白细胞介素-5水平的变化
Q4 Medicine Pub Date : 2022-03-28 DOI: 10.5604/01.3001.0015.8113
D. Irfandy, Hirowati Ali, Effy Huriyati, B. J. Budiman, Hafni Bachtiar, E. Wahyudi
Introduction: Chronic rhinosinusitis (CRS) is an inflammation of the nasal mucosa and paranasal sinuses that is present for more than 12 weeks. The pathogenesis of allergic CRS includes mucosal edema and causes sinus ostial obstruction, which. It leads to the infection of the paranasal sinuses. Interleukin- 5 (IL-5) is a cytokine and acts in eosinophil and basophil biology. It is the main effector unit of allergic reactions. Aim: This study aimed to determine IL-5 levels in allergic and nonallergic chronic rhinosinusitis patients. Material and methods: A comparative analytic cross-sectional study was used. A total of 10 allergic chronic and 10 nonallergic chronic rhinosinusitis patients took part in this study. The real-time polymerase chain reaction (RT-PCR) method was used to determine gene expression. Data were analyzed with SPSS. A p-value below 0.05 was considered statistically significant. Results: IL-5 gene expression in non-allergic chronic rhinosinusitis was higher than in allergic chronic rhinosinusitis. IL-5 gene expression was not significant between chronic non-allergic and allergic chronic rhinosinusitis (p > 0.05). There was an elevated IL-5 gene expression in non-allergic chronic rhinosinusitis, but it was not significant compared to chronic allergic rhinosinusitis.
慢性鼻窦炎(CRS)是一种持续12周以上的鼻黏膜和副鼻窦炎症。过敏性CRS的发病机制包括粘膜水肿和引起鼻窦口梗阻。它会导致鼻窦感染。白细胞介素-5 (IL-5)是一种细胞因子,在嗜酸性粒细胞和嗜碱性粒细胞生物学中起作用。它是过敏反应的主要作用单位。目的:本研究旨在测定变应性和非变应性慢性鼻窦炎患者IL-5水平。材料和方法:采用比较分析的横断面研究。共有10名过敏性慢性鼻窦炎患者和10名非过敏性慢性鼻窦炎患者参加了这项研究。采用实时聚合酶链反应(RT-PCR)法检测基因表达。数据采用SPSS统计软件进行分析。p值小于0.05被认为具有统计学意义。结果:IL-5基因在非变应性慢性鼻窦炎中的表达高于变应性慢性鼻窦炎。IL-5基因在慢性非变应性和变应性慢性鼻窦炎中的表达差异无统计学意义(p < 0.05)。非变应性慢性鼻窦炎患者IL-5基因表达升高,但与慢性变应性鼻窦炎患者相比差异不显著。
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引用次数: 0
Nasal irrigation with Zatoxin Rinse in postoperative care Zatoxin冲鼻液在术后护理中的应用
Q4 Medicine Pub Date : 2022-03-25 DOI: 10.5604/01.3001.0015.8100
E. Brożek-Mądry, Z. Steć, Z. Burska, A. Krzeski
Aim: The aim of this study was to assess the effect of nasal irrigation with isotonic sodium chloride and sodium bicarbonatesolution in the form of Zatoxin Rinse kit on the process of postopera-tive wound healing and resolution of inflammation inpatients who undergo surgery of the nasal cavity or paranasal sinuses. Moreover, our study also compared the effectivenessof na-sal irrigation with Zatoxin Rinse kit to the use of saline spray, when applied for 4 weeks after nasal septum surgery. Material and methods: Multicenter observational studies were conducted with the use of a questionnaire which was filledouton two consecutive visits, scheduled with a 1-month interval. These questionnaires applied to patients who underwentendoscopic surgical intervention in the nasal cavity and paranasal sinuses and were therefore qualified for this study.The study group included 71 patients (mean age: 42.87 ± 13.22 years; 29 female and 42 male) suffering from the followingdisorders: chronic rhinosinusitis (CRS) with polyps, n = 25; CRS without polyps, n = 19; de-viated septum, n = 27. The controlgroup included 7 patients with deviated septum (using saline nasal products/seawater spray). Based on the questionnaireresults and ENT examina-tion, the severity of inflammation and effectiveness of wound healing were assessed with the useof: SNOT-22 (sino-nasal outcome score), Visual Analogue Scale (VAS) and endoscopic examination of nasal cavities.Results: The median value for results obtained from the SNOT-22 questionnaire was 38 points (IQR = 36) in CRS withoutpolyps, 33 points (IQR = 24) in CRS with polyps and 26 points (IQR = 19) in deviated septum. The median values for all scoresrecorded in specific subgroups after 4 weeks of applying Zatoxin Rinse were as follows: patients with CRS with polyps: 7points (IQR = 9.5), patients with CRS without polyps: 5 points (IQR = 13), patients with deviated septum: 6 points (IQR = 9).Postoperative nasal discharge was observed to be the most fre-quent in patients with CRS: among patients suffering fromCRS with polyps, the median VAS scale result was 6 points (IQR = 4), while the median for patients diagnosed with CRSwithout polyps was 6 points (IQR = 5) and 3 points (IQR = 4) in the group with deviated septum. The feeling of impairednasal patency in the postoperative period was reported to be the strongest in patients diagnosed with CRS without polyps:8 points (IQR = 5), as com-pared to 5 points (IQR = 4.5) in patients with CRS with polyps and 5 points (IQR = 7) in the deviatedseptum group. Postoperative smell disorders were observed to be expressed as more severe among patients with CRSwithout polyps: 6 points (IQR = 4) and less severe in pa-tients with CRS with polyps: 4 points (IQR = 7). After 4 weeks of healingaided by irrigation of paranasal sinuses with the use of Zatoxin Rinse kit, patients from all subgroups experienced astatistically significant reduction in the severity of all parameters assessed
目的:本研究的目的是评估等渗氯化钠和碳酸氢钠溶液以Zatoxin冲洗试剂盒的形式鼻腔冲洗对鼻腔或鼻窦手术患者术后伤口愈合和炎症消退的影响。此外,我们的研究还比较了在鼻中隔手术后4周使用Zatoxin漂洗试剂盒进行鼻腔冲洗和使用生理盐水喷雾的效果。材料和方法:采用问卷调查的方式进行多中心观察性研究,问卷在两次连续访问中填写,间隔1个月。这些问卷适用于接受鼻腔和鼻窦内窥镜手术干预的患者,因此符合本研究的要求。研究组纳入71例患者,平均年龄42.87±13.22岁;29例女性,42例男性)患有以下疾病:慢性鼻窦炎(CRS)伴息肉,n = 25;无息肉的CRS, n = 19;鼻中隔脱位,n = 27。对照组为7例鼻中隔偏曲患者(使用生理盐水鼻用品/海水喷雾)。根据问卷调查结果和耳鼻喉科检查,采用鼻内镜检查、鼻黏膜模拟评分(ssnot -22)、视觉模拟评分(VAS)和鼻腔内镜检查评估炎症严重程度和伤口愈合效果。结果:SNOT-22问卷结果的中位数为无息肉的CRS为38分(IQR = 36),有息肉的CRS为33分(IQR = 24),中隔偏曲的CRS为26分(IQR = 19)。应用Zatoxin Rinse 4周后,特定亚组记录的所有评分中位数如下:CRS合并息肉患者:7分(IQR = 9.5), CRS无息肉患者:5分(IQR = 13),鼻中隔偏曲患者:6分(IQR = 9)。CRS患者术后最常出现鼻分泌物。伴有息肉的crs患者VAS评分中位数为6分(IQR = 4),无息肉的crs患者VAS评分中位数为6分(IQR = 5),中隔偏曲组VAS评分中位数为3分(IQR = 4)。据报道,无息肉的CRS患者术后鼻通畅受损感最强:8分(IQR = 5),有息肉的CRS患者为5分(IQR = 4.5),鼻中隔偏曲组为5分(IQR = 7)。观察到术后嗅觉障碍在无息肉的CRS患者中表现为更严重:6分(IQR = 4),而在有息肉的CRS患者中表现为更轻:4分(IQR = 7)。在使用Zatoxin冲洗工具包辅助鼻窦冲洗4周后,所有亚组患者的所有参数的严重程度均有统计学意义上的显著降低。在使用ZatoxinRinse试剂盒冲洗鼻腔之前,使用Lund-Kennedy评分系统对鼻腔进行内镜评估,诊断为CRS合并息肉的患者记录的结果最高:10分(IQR = 9.5),而诊断为CRS无息肉的患者为8分(IQR = 6),鼻中隔偏曲患者为6分(IQR = 5)。4周后,有息肉的CRS组的中位结果为3分(IQR = 3.5),无息肉的CRS组和鼻中隔偏曲组的中位结果相同,均为3分(IQR = 3)。结论:(1)Zatoxin Rinse冲洗鼻腔耐受性好,易于操作。71例受试者未发现鼻冲洗的不良反应,患者对Zatoxin漂洗试剂盒提供的应用方法满意;(2)与使用生理盐水喷雾相比,Zatoxin Rinse能促进鼻窦或鼻中隔手术干预患者的术后伤口愈合。
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引用次数: 0
Myogenic sarcoma of larynx – a case report and review of the literature 喉肌源性肉瘤1例报告及文献复习
Q4 Medicine Pub Date : 2022-03-21 DOI: 10.5604/01.3001.0015.8082
Maria Molga-Magusiak, Małgorzata A Czesak, Anna Furman, E. Osuch-Wójcikiewicz
Introduction: Myogenic sarcomas (MS) are malignant tumors of mesenchymal origin that include sarcomas of smooth muscle differentiation (leiomyosarcoma, LM) and skeletal muscle differentiation (rhabdomyosarcoma, RM). These neoplasms are extremely rare entities in larynx and often cause diagnostic difficulties. Case: We present a case of laryngeal myogenic sarcoma partially differentiated into LM, treated with a surgical resection and an adjuvant radiotherapy. This study presents management and treatment according to the current literature.
引言:肌源性肉瘤(MS)是间充质来源的恶性肿瘤,包括平滑肌分化型肉瘤(平滑肌肉瘤,LM)和骨骼肌分化型肉瘤。这些肿瘤在喉部是极为罕见的实体,经常引起诊断困难。病例:我们报告了一例部分分化为LM的喉肌源性肉瘤,通过手术切除和辅助放疗进行治疗。本研究根据现有文献介绍管理和治疗。
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引用次数: 0
Speech therapy rehabilitation in an otorhinolaryngologicalpatient against the Polish legal regulations 针对波兰法律规定的一名耳鼻喉科患者的言语治疗康复
Q4 Medicine Pub Date : 2022-03-21 DOI: 10.5604/01.3001.0015.8098
Jagoda Kałużna, K. Miszczak, Natalia Tuz-Hrycyna, A. Rzepakowska, K. Niemczyk
Introduction: The challenges of modern medicine go beyond merely effective diagnostics and therapy for extension ofhuman life, but must also strive to improve its quality. The benefits of multidisciplinary cooperation in patient care are nowunquestionable and result in the dissemination of such a trend among most medical fields. Clinical speech therapists arevaluable partners for otorhinolaryngologists in the treatment of many diseases of the head and neck region.Aim: The aim of this article is to present the role of the speech therapist at an otorhinolaryngology ward, as well as to analyzethe current legal regulations that constitute the basis for such cooperation. In accordance with the legal regulations currentlyin force in Poland, the position of a speech therapist at the otolaryngology department is financed for the rehabilitationof patients with cochlear implant and brain stem implants. Unfortunately, the role of a speech therapist in other diseasesincluding voice, speech, hearing and swallowing disorders within otorhinolaryngology wards has not yet been sanctioned,hence many patients continue to be deprived of comprehensive pre- and postoperative care.Conclusion: Speech therapy rehabilitation in ENT departments, apart from patients with hearing loss, is particularly importantfor patients with organic lesions of the larynx undergoing intra-laryngeal surgery as well as open surgery procedures,patients with neurogenic voice and/or swallowing disorders or as a result of iatrogenic dysfunction. Such therapy includesdiagnostic and information activities as well as exercises to improve functions. Speech therapists contribute substantially tothe comprehensive care of patients both in the preoperative and postoperative periods.
引言:现代医学的挑战不仅仅是为了延长人类生命而进行有效的诊断和治疗,还必须努力提高其质量。多学科合作在患者护理方面的好处现在是毋庸置疑的,并导致这种趋势在大多数医疗领域传播。临床言语治疗师是耳鼻喉科医生治疗头颈部多种疾病的宝贵合作伙伴。目的:本文旨在介绍耳鼻喉科病房言语治疗师的角色,并分析构成此类合作基础的现行法律法规。根据波兰现行的法律规定,耳鼻喉科言语治疗师的职位由资助,用于耳蜗植入和脑干植入患者的康复。不幸的是,在耳鼻喉科病房内,言语治疗师在其他疾病(包括声音、言语、听力和吞咽障碍)中的作用尚未得到批准,因此许多患者仍然被剥夺了全面的术前和术后护理。结论:除听力损失患者外,耳鼻喉科的言语治疗康复对接受喉内手术和开放手术的喉器质性病变患者、神经源性语音和/或吞咽障碍患者或医源性功能障碍患者尤为重要。这种治疗包括诊断和信息活动以及改善功能的锻炼。言语治疗师在术前和术后对患者的全面护理做出了重大贡献。
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引用次数: 0
Giant frontal sinus osteoma - case report and literature review 巨大额窦骨瘤1例报告并文献复习
Q4 Medicine Pub Date : 2022-03-10 DOI: 10.5604/01.3001.0015.7964
S. Piotrowski, Marta Jagłowska
Osteomas of paranasal sinuses larger than 3 cm are classified as giant osteomas. A considerable size of these tumors may result in serious complications as well as pose a substantial surgical challenge. We present a case of an adult man with a giant osteoma of right frontal sinus. The neoplasm was removed in an open approach with incision along the brow bridge; an injury to the supraorbital nerve was avoided. The osteotomy was performed with piezosurgery. The anterial wall of the right frontal sinus was reconstructed with bone fragments bound together by titanium plates and mesh. The following discussion presents different possibilities of surgical removal of giant paranasal osteomas.
鼻窦骨瘤大于3cm者为巨大骨瘤。这些肿瘤的相当大的大小可能导致严重的并发症,并提出了实质性的手术挑战。我们报告一个成年男性右额窦巨大骨瘤的病例。肿瘤沿眉桥开切口切除;避免了眶上神经的损伤。骨切开术采用压电外科手术。用钛板和网片结合骨碎片重建右额窦前壁。下面讨论了手术切除巨大鼻旁骨瘤的不同可能性。
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引用次数: 0
Congenital spontaneous otogenic cerebrospinal fluid leak as a cause of recurrent meningitis in a 9-year-old child – case report and literature review 先天性自发性耳源性脑脊液漏致9岁儿童复发性脑膜炎1例报告及文献复习
Q4 Medicine Pub Date : 2022-03-10 DOI: 10.5604/01.3001.0015.7969
Katarzyna Amernik, E. Jaworowska
Introduction: Congenital otogenic CSF leak is a rare cause of meningitis. The underlying reason may be a defect of the fundus of internal auditory meatus with pathological communication with the inner ear and CSF leak to middle ear space. This condition requires surgical closure. Case report: A 9-year-old boy with a history of recurrent meningitis – 3 episodes. During the last episode, β-2 transferrin test from ear fluid was positive. The patient complained of leakage of clear fluid through the nose on the right side. Otoscopy revealed a bulging tympanic membrane on the right side. The right ear was deaf with normal hearing on the left side. HRCT revealed congenital deformity of the right inner ear. Right side lateral petrosectomy with blind sac closure of the right external auditory canal was performed. During surgery there was an extensive CSF leak through the oval window niche due to a lack of the stapes footplate in the anterior part. Recovery was uneventful. After 24 months of follow up, no more leakage through the nose was observed. Control magnetic resonance performed one year after surgery showed no CSF in the mastoid cavity. Discussion: Inner ear malformations are a rare cause of meningitis, and the most common sites of congenital otogenic CSF leakage include the oval and round window. Surgical closure is the only solution in such cases. Several methods of sealing the inner ear space were described in the literature. Vestibular packing and stapedectomy were most frequently used. However, recurrences were stated in up to 1/2 of cases. Such a risk can be limited with lateral petrosectomy. For this reason, LP can be considered as the treatment of choice in congenital spontaneous otogenic cerebrospinal fluid leak. Conclusion: Every case of recurrent meningitis in children should be investigated with a suspicion of congenital ear malformation with spontaneous CSF leakage. Lateral petrosectomy is a safe and effective procedure for cases of otogenic CSF leak with a low risk of recurrence.
简介:先天性耳源性脑脊液漏是一种罕见的脑膜炎病因。其根本原因可能是内耳道底缺损,与内耳病理性相通,脑脊液渗漏至中耳间隙。这种情况需要手术治疗。病例报告:一名九岁男童,有三次复发性脑膜炎病史。最后一次发病时耳液β-2转铁蛋白检测呈阳性。病人主诉有透明液体从右侧鼻子漏出。耳镜检查显示右侧鼓膜膨出。右耳失聪,左耳听力正常。HRCT显示先天性右内耳畸形。行右侧外侧石油切开术,盲囊封闭右侧外耳道。在手术中,由于前部镫骨足板缺失,通过卵圆形窗位出现了广泛的脑脊液泄漏。恢复过程平淡无奇。随访24个月后,未见鼻漏。术后一年对照磁共振显示乳突腔内无脑脊液。讨论:内耳畸形是一种罕见的脑膜炎的原因,最常见的先天性耳源性脑脊液漏的位置包括椭圆形和圆形窗口。手术是这种情况下唯一的解决办法。文献中介绍了几种封闭内耳空间的方法。前庭填充和镫骨切除术是最常用的方法。然而,复发率高达1/2。这种风险可以通过外侧石油切除术加以限制。因此,LP可作为先天性自发性耳源性脑脊液漏的首选治疗方法。结论:每一例儿童复发性脑膜炎病例都应考虑先天性耳畸形并自发性脑脊液渗漏。侧边石切开术是治疗耳源性脑脊液渗漏安全有效的方法,复发风险低。
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引用次数: 1
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Polish Otorhinolaryngology Review
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