Pub Date : 2018-09-30DOI: 10.18287/JBPE18.04.030302
M. M. Hossain, Rajib Mandal, Md. Ziual Amin, H. S. Mondal, Md. Ekhlasur Rahaman
A new temperature sensor based on asymmetry in dual circular core photonic crystal fiber (ADCPCF) is proposed where both the cores infiltrate by chloroform. To analyze the temperature dependent propagation characteristics, the thermo-optic coefficient of chloroform and silica is used. The asymmetry of the dual-core is confirmed by using the core radius of 1.615 and 1.45 µm, respectively. In the proposed design, the essential optical properties such as effective refractive index difference (birefringence), coupling length, and transmission spectra are determined by employing the finite element method (FEM) with the perfectly matched layer (PML). The effective refractive index of the chloroform varies with temperature within a certain range. Moreover, with the increase of every 1 °C temperature the effective index difference enhances to almost 4%. Also, with the reduction of every 100 nm wavelength the birefringence decrease to 0.125×10 -3 and 0.092×10 -3 for 35 and 30 °C temperature, respectively. The Numeric analysis shows the maximum sensitivity of 49.80 nm/°C at 1.61 mm fiber length for 2.9 µm lattice pitch with 2.25 µm air-hole diameter. Furthermore, every 1 °C temperature increment, the proposed ADCPCF exhibits approximately 16% increases of sensitivity than the existing result. In addition, the proposed ADCPCF reveals that the guiding properties like coupling length, birefringence, and transmission spectra are wavelength and temperature reliance.
{"title":"Chloroform infiltrate temperature sensor using asymmetric circular dual-core photonic crystal fiber","authors":"M. M. Hossain, Rajib Mandal, Md. Ziual Amin, H. S. Mondal, Md. Ekhlasur Rahaman","doi":"10.18287/JBPE18.04.030302","DOIUrl":"https://doi.org/10.18287/JBPE18.04.030302","url":null,"abstract":"A new temperature sensor based on asymmetry in dual circular core photonic crystal fiber (ADCPCF) is proposed where both the cores infiltrate by chloroform. To analyze the temperature dependent propagation characteristics, the thermo-optic coefficient of chloroform and silica is used. The asymmetry of the dual-core is confirmed by using the core radius of 1.615 and 1.45 µm, respectively. In the proposed design, the essential optical properties such as effective refractive index difference (birefringence), coupling length, and transmission spectra are determined by employing the finite element method (FEM) with the perfectly matched layer (PML). The effective refractive index of the chloroform varies with temperature within a certain range. Moreover, with the increase of every 1 °C temperature the effective index difference enhances to almost 4%. Also, with the reduction of every 100 nm wavelength the birefringence decrease to 0.125×10 -3 and 0.092×10 -3 for 35 and 30 °C temperature, respectively. The Numeric analysis shows the maximum sensitivity of 49.80 nm/°C at 1.61 mm fiber length for 2.9 µm lattice pitch with 2.25 µm air-hole diameter. Furthermore, every 1 °C temperature increment, the proposed ADCPCF exhibits approximately 16% increases of sensitivity than the existing result. In addition, the proposed ADCPCF reveals that the guiding properties like coupling length, birefringence, and transmission spectra are wavelength and temperature reliance.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47638476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18287/JBPE18.04.020303
D. Artemyev
Optical methods are increasingly being used for the early diagnosis of skin cancer. This approach allows for detecting the component composition changes of tissue in a non-invasive manner. Autofluorescence spectroscopy is a sensitive method for tumor diagnosis and the method availability distinguishes it among other approaches. This work is devoted to fluorescence modeling of skin tissues induced by 450 nm radiation. A multilayer skin model was developed using a set of fluorophores (eumelanin, lipofuscin, riboflavin, beta-carotene, bilirubin) matched with excitation radiation. Model autofluorescence spectra of normal skin tissues of the northern phenotype and pathological changes were obtained. The results were compared with the results of previous experimental studies of ex vivo autofluorescence spectra of the skin and neoplasms.
{"title":"Mathematical model of skin autofluorescence induced by 450 nm laser","authors":"D. Artemyev","doi":"10.18287/JBPE18.04.020303","DOIUrl":"https://doi.org/10.18287/JBPE18.04.020303","url":null,"abstract":"Optical methods are increasingly being used for the early diagnosis of skin cancer. This approach allows for detecting the component composition changes of tissue in a non-invasive manner. Autofluorescence spectroscopy is a sensitive method for tumor diagnosis and the method availability distinguishes it among other approaches. This work is devoted to fluorescence modeling of skin tissues induced by 450 nm radiation. A multilayer skin model was developed using a set of fluorophores (eumelanin, lipofuscin, riboflavin, beta-carotene, bilirubin) matched with excitation radiation. Model autofluorescence spectra of normal skin tissues of the northern phenotype and pathological changes were obtained. The results were compared with the results of previous experimental studies of ex vivo autofluorescence spectra of the skin and neoplasms.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48035294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-29DOI: 10.18287/JBPE18.04.020201
D. K. Tuchina, V. Tuchin
Diabetes mellitus is a serious social and economic problem of modern society because it is widespread and fraught with numerous complications. Therefore, it is necessary to search for new methods of diabetes mellitus diagnostics and treatment and to improve the existing ones, which, in turn, requires thorough investigation of the disease development mechanisms, as well as elaboration of simple and reliable methods and criteria for detecting the complication precursors. In connection with the solution of these problems, in the paper we present an analytical review of recent publications devoted to the study of the changes of structural and optical properties of biological tissues under the conditions of diabetes mellitus development using in vitro models of glycated tissues, in vivo experimental models of diabetes in laboratory animals, and clinical studies.
{"title":"Optical and structural properties of biological tissues under diabetes mellitus","authors":"D. K. Tuchina, V. Tuchin","doi":"10.18287/JBPE18.04.020201","DOIUrl":"https://doi.org/10.18287/JBPE18.04.020201","url":null,"abstract":"Diabetes mellitus is a serious social and economic problem of modern society because it is widespread and fraught with numerous complications. Therefore, it is necessary to search for new methods of diabetes mellitus diagnostics and treatment and to improve the existing ones, which, in turn, requires thorough investigation of the disease development mechanisms, as well as elaboration of simple and reliable methods and criteria for detecting the complication precursors. In connection with the solution of these problems, in the paper we present an analytical review of recent publications devoted to the study of the changes of structural and optical properties of biological tissues under the conditions of diabetes mellitus development using in vitro models of glycated tissues, in vivo experimental models of diabetes in laboratory animals, and clinical studies.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48916891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-17DOI: 10.18287/JBPE18.04.020302
O. Baum, A. K. Dmitriev, V. Kortunov, O. A. Tiflova, V. A. Ul’yanov
One of the trends in the development of modern regeneration medicine is the application of high-intensity laser radiation for deep perforation of biological tissues, stimulating the regeneration of structure and functions of the pathologically changed tissues. In the paper, the possibility to control the location and parameters of the biotissue thermal stimulation zones is studied theoretically and experimentally, depending on the conditions of laser perforation in application to the liver laser-induced regeneration problem. The results of numerical simulation revealed the basic trends in the behaviour of the thermal stimulation zone, which are in good agreement with the experimental data on laser perforation of soft biotissues ex vivo using an optical fibre.
{"title":"Thermal effect in laser perforation of liver","authors":"O. Baum, A. K. Dmitriev, V. Kortunov, O. A. Tiflova, V. A. Ul’yanov","doi":"10.18287/JBPE18.04.020302","DOIUrl":"https://doi.org/10.18287/JBPE18.04.020302","url":null,"abstract":"One of the trends in the development of modern regeneration medicine is the application of high-intensity laser radiation for deep perforation of biological tissues, stimulating the regeneration of structure and functions of the pathologically changed tissues. In the paper, the possibility to control the location and parameters of the biotissue thermal stimulation zones is studied theoretically and experimentally, depending on the conditions of laser perforation in application to the liver laser-induced regeneration problem. The results of numerical simulation revealed the basic trends in the behaviour of the thermal stimulation zone, which are in good agreement with the experimental data on laser perforation of soft biotissues ex vivo using an optical fibre.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42515594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-31DOI: 10.18287/JBPE17.03.020101
A. Mayorova, V. Zakharov
For the sixth time, it is our pleasure to present you the Special Issue of the Journal of Biomedical Photonics & Engineering (J-BPE) with selected papers of the Biophotonics Workshop of the XVIII All-Russian Youth Conference-Contest on Optics and Laser Physics (Samara, November 10-14, 2020). The conference-contest was organized by P.N. Lebedev Physical Institute (Samara Branch) and Samara National Research University and supported by Administration of Samara Region and Samara SPIE Student Chapter.
{"title":"Foreword to the Special Issue on Laser and optical technologies in biomedicine and ecology","authors":"A. Mayorova, V. Zakharov","doi":"10.18287/JBPE17.03.020101","DOIUrl":"https://doi.org/10.18287/JBPE17.03.020101","url":null,"abstract":"For the sixth time, it is our pleasure to present you the Special Issue of the Journal of Biomedical Photonics & Engineering (J-BPE) with selected papers of the Biophotonics Workshop of the XVIII All-Russian Youth Conference-Contest on Optics and Laser Physics (Samara, November 10-14, 2020). The conference-contest was organized by P.N. Lebedev Physical Institute (Samara Branch) and Samara National Research University and supported by Administration of Samara Region and Samara SPIE Student Chapter.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46631283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01Epub Date: 2016-02-01DOI: 10.18287/JBPE-2015-1-4-209
Jiawen Li, Zhongping Chen
Heart attack is mainly caused by the rupture of a vulnerable plaque. IVUS-OCT is a novel medical imaging modality that provides opportunities for accurate assessment of vulnerable plaques in vivo in patients. IVUS provides deep penetration to image the whole necrotic core while OCT enables accurate measurement of the fibrous cap of a plaque owing to its high resolution. In this paper, the authors describe the fundamentals, the technical designs and the applications of IVUS-OCT technology. Results from cadaver specimens are summarized, which indicated the complementary nature of OCT and IVUS for assessment of vulnerable plaques, plaque composition, and stent-tissue interactions. Furthermore, previously reported in vivo animal experiments are reviewed to assess the clinical adaptability of IVUS-OCT. Future directions for this technology are also discussed in this review.
{"title":"Integrated intravascular ultrasound and optical coherence tomography technology: a promising tool to identify vulnerable plaques [INVITED PAPER].","authors":"Jiawen Li, Zhongping Chen","doi":"10.18287/JBPE-2015-1-4-209","DOIUrl":"https://doi.org/10.18287/JBPE-2015-1-4-209","url":null,"abstract":"<p><p>Heart attack is mainly caused by the rupture of a vulnerable plaque. IVUS-OCT is a novel medical imaging modality that provides opportunities for accurate assessment of vulnerable plaques <i>in vivo</i> in patients. IVUS provides deep penetration to image the whole necrotic core while OCT enables accurate measurement of the fibrous cap of a plaque owing to its high resolution. In this paper, the authors describe the fundamentals, the technical designs and the applications of IVUS-OCT technology. Results from cadaver specimens are summarized, which indicated the complementary nature of OCT and IVUS for assessment of vulnerable plaques, plaque composition, and stent-tissue interactions. Furthermore, previously reported <i>in vivo</i> animal experiments are reviewed to assess the clinical adaptability of IVUS-OCT. Future directions for this technology are also discussed in this review.</p>","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615859/pdf/nihms850847.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35562482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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