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COP27 Climate Change Conference: Urgent Action needed for Africa and the World COP27气候变化大会:非洲和世界需要采取紧急行动
Pub Date : 2022-12-23 DOI: 10.30442/ahr.0804-01-176
Centre for Global Health UK
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引用次数: 0
Relationship Between Subchorionic Haematoma and Abdominal Massage in Pregnancy in the Niger Delta Region of Nigeria: A Pilot Study 尼日利亚尼日尔三角洲地区孕妇绒毛膜下血肿与腹部按摩的关系:一项试点研究
Pub Date : 2022-12-23 DOI: 10.30442/ahr.0804-06-181
E. Kiridi, P. Oriji, C. Okechukwu, D. Briggs, J. Ugwoegbu, AE Ubom, A. Addah, I. Abasi, P. Bosrotsi, A. Adesina
Background: Abdominal massage (AM) in pregnancy is a common practice in the Niger Delta region of Nigeria. AM may cause events such as subchorionic haematoma (SAH) and increase the risk of miscarriages and adverse maternal and perinatal outcomes.Objective: To determine the relationship between AM and SCH in the Niger Delta region of Nigeria.Methods: A cross-sectional study was conducted from January to June 2022 at the Obstetrics and Radiology Units of four health facilities in Bayelsa State, Nigeria. Consenting eligible pregnant women presenting to the antenatal clinic during the first trimester were consecutively included. An obstetric ultrasound scan was performed transabdominal.Results: Of the 403 women recruited, 241 (59.8%) were aged (20 – 29 years). The mean age was 28.02 ± 5.99 years. The mean body mass index was 23.82±4.60 kg/m2. While 170 (42.2%) had undergone AM in the first trimester of the index pregnancy, 126 (31.3%) had vaginal bleeding, and SCH occurred in 109 (27.0%) women. Women who had AM had 210 (CI: 58 – 878) times the odds of having SCH and 3.3 (CI: 2.14 – 5.15) times the odds of vaginal bleeding than women who did not have AM. Only 2 (1.8%) women with SCH did not have AM.Conclusion: There exists a strong association between the occurrence of SCH among pregnant women who have had AM. More health education is needed for women in the Niger Delta region and Nigeria to eradicate the archaic practice and improve pregnancy outcomes.
背景:妊娠期腹部按摩(AM)是尼日利亚尼日尔三角洲地区的一种常见做法。AM可能导致事件,如绒毛膜下血肿(SAH),并增加流产和不良产妇和围产期结局的风险。目的:探讨尼日利亚尼日尔三角洲地区AM与SCH的关系。方法:于2022年1月至6月在尼日利亚巴耶尔萨州四家卫生机构的产科和放射科进行了一项横断面研究。连续纳入在妊娠早期到产前诊所就诊的符合条件的孕妇。经腹行产科超声扫描。结果:入选的403名女性中,年龄在20 ~ 29岁的有241名(59.8%)。平均年龄28.02±5.99岁。平均体重指数为23.82±4.60 kg/m2。170例(42.2%)在指标妊娠的前三个月发生AM, 126例(31.3%)发生阴道出血,109例(27.0%)发生SCH。患有AM的女性患SCH的几率是没有AM的女性的210倍(CI: 58 - 878),阴道出血的几率是3.3倍(CI: 2.14 - 5.15)。仅有2例(1.8%)SCH患者没有AM。结论:AM孕妇中SCH的发生有较强的相关性。需要对尼日尔三角洲地区和尼日利亚的妇女进行更多的健康教育,以根除这种古老的做法并改善妊娠结果。
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引用次数: 0
The Forms, Challenges and Strength of the Monkeypox Surveillance System in Nigeria 尼日利亚猴痘监测系统的形式、挑战和力量
Pub Date : 2022-12-23 DOI: 10.30442/ahr.0804-03-178
ON Olaleke, OJ Okesanya, SM Abioye, MO Othoigbe, EE Matthew, M. Emery, AA Isaiah, TM Odugbile, BG Adebayo, DE Lucero-Prisno III
Monkeypox is now a disease of global public health concern, making it cut across boundaries into different countries, continents and spread worldwide. However, it originated in the Democratic Republic of Congo as a human pathogen in 1970, with the first case reported in Nigeria in 1971. The World Health Organization recently declared Nigeria the country with the highest burden of monkeypox-confirmed cases and deaths in Africa for the current outbreak. This study aimed to identify forms, challenges, strengths, and ways to further strengthen the surveillance system of monkeypox in Nigeria. We conducted a rapid narrative review of articles published in English on monkeypox between January 2018 and October 2022. Google Scholar and PubMed were searched with the following terms: "Monkeypox", "Surveillance system", "Strengthening", "Challenges" "Nigeria" and relevant publications were reviewed. The forms of surveillance systems in Nigeria include Indicator-based and Event-based surveillance, contact tracing, laboratory-based surveillance, sero-surveillance, and mortality surveillance. Shortage of highly skilled staff in public health interventions, insufficient testing capacities, power instability, poor healthcare systems and stigmatization from communities with misinformation, and co-epidemic surveillance burden in Nigeria are some of the challenges contributing to weak surveillance in the country. The Nigerian governments must focus on investing in surveillance systems and bolster preparedness to stem the rapid spread of infectious diseases. Strengthening the surveillance system in the country as a response intervention for monkeypox is no longer a matter of option in Nigeria but of necessity to prevent the forecasted effect the incidence portends.
猴痘现在是一种全球公共卫生关注的疾病,它跨越国界传播到不同的国家、大洲并在全球范围内传播。然而,它于1970年作为人类病原体起源于刚果民主共和国,1971年在尼日利亚报告了第一例病例。世界卫生组织最近宣布,尼日利亚是非洲猴痘确诊病例和死亡人数最多的国家。这项研究旨在确定猴痘的形式、挑战、优势和进一步加强尼日利亚猴痘监测系统的方法。我们对2018年1月至2022年10月期间发表的关于猴痘的英文文章进行了快速叙述性综述。谷歌学者和PubMed搜索了以下术语:“猴痘”、“监测系统”、“加强”、“挑战”、“尼日利亚”,并对相关出版物进行了审查。尼日利亚的监测系统形式包括基于指标和基于事件的监测、接触者追踪、基于实验室的监测、血清监测和死亡率监测。尼日利亚缺乏公共卫生干预方面的高技能工作人员、检测能力不足、电力不稳定、糟糕的医疗保健系统和来自错误信息社区的污名化,以及共同流行病监测负担,这些都是导致该国监测不力的一些挑战。尼日利亚政府必须专注于对监测系统的投资,并加强准备,以阻止传染病的快速传播。在尼日利亚,加强该国的监测系统作为猴痘的应对干预措施不再是一个选择,而是预防猴痘发病率预示的预测影响的必要性。
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引用次数: 2
The Impact of Telemedicine During the COVID-19 Pandemic in Nigeria: A Review 远程医疗在尼日利亚新冠肺炎大流行期间的影响:综述
Pub Date : 2022-12-23 DOI: 10.30442/ahr.0804-02-177
I. Ezeani, GC Okwuonu, I. Chukwuonye, M. Nkpozi
Background: Telemedicine practice is a rapidly evolving aspect of medicine in developed countries, though resource-limited countries like Nigeria are yet to embrace it fully. Moreover, the COVID-19 pandemic has limited patients’ visits to hospitals in addition to the social distancing measures deployed by the government. In addition, with the challenges of a limited number of doctors, among other difficulties, it has become important that a radical approach to patient care and treatment should be explored.Methods: A comprehensive literature review of original articles was done using an internet search. Words such as Telemedicine, COVID-19, Pandemic, Requirements, History, Benefits, and Challenges were searched on Google scholar, EMBASE, PubMed, Medline, Web MD, and Scopus to check for various articles published or any probable link. The references of the relevant articles were searched.Results: The practice of telemedicine has evolved over the years. Also, the global telemedicine market has grown exponentially and is expected to grow even further in the next five years. Unfortunately, this exciting narrative is not obtainable in developing countries like Nigeria. Indeed, some healthcare providers in Nigeria need to prepare for this new technological advancement, and consequently, they struggle to evolve their practice to adopt this new technology. Furthermore, there is disinterest from most of the end users, particularly the patients.Conclusion: Modifications must involve telemedicine services with a view of getting ready and well-organized in the event of any future pandemic such as COVID-19, in addition to harnessing the benefits of this service in the future.
背景:远程医疗实践是发达国家医学快速发展的一个方面,尽管尼日利亚等资源有限的国家尚未完全接受它。此外,除了政府采取的保持社会距离措施外,新冠肺炎疫情也限制了患者的医院就诊。此外,由于医生数量有限的挑战,以及其他困难,探索一种激进的病人护理和治疗方法变得很重要。方法:通过网络检索,对原始文献进行全面的文献综述。在谷歌scholar、EMBASE、PubMed、Medline、Web MD和Scopus等网站上搜索远程医疗、COVID-19、Pandemic、Requirements、History、Benefits和Challenges等关键词,查看已发表的各种文章或任何可能的链接。检索了相关文章的参考文献。结果:远程医疗的实践已经发展了多年。此外,全球远程医疗市场呈指数级增长,预计在未来五年内将进一步增长。不幸的是,这种令人兴奋的叙述在尼日利亚这样的发展中国家是无法实现的。事实上,尼日利亚的一些医疗保健提供者需要为这种新技术的进步做好准备,因此,他们努力发展自己的实践,以采用这种新技术。此外,大多数终端用户,特别是患者对它不感兴趣。结论:修改必须涉及远程医疗服务,以便在未来发生COVID-19等任何大流行时做好准备并做好组织工作,并在未来利用该服务的优势。
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引用次数: 0
Late Effects of Therapy, Stigmatization and Social Reintegration following Childhood Cancer Survival in Kenya: A Case Report 肯尼亚儿童癌症生存后治疗、污名化和社会融合的后期影响:一例病例报告
Pub Date : 2022-12-23 DOI: 10.30442/ahr.0804-08-183
Jpm Lemmen, N. Midiwo, F. Njuguna, G. Kaspers, S. Mostert
Childhood cancer survival is increasing in low- and middle-income countries like Kenya, which comes with a new healthcare challenge: late effects and quality-of-life of survivors. A case was studied to depict a Kenyan Hodgkin lymphoma survivor, illustrating some of the childhood cancer survivors' difficulties in Kenya. Late effects of therapy, stigmatization and social reintegration were explored. The investigators reviewed medical records and used semi-structured interviews and stigma assessments using the Social Impact Scale. The survivor developed severe pulmonary hypertension during treatment with ABVD and salvage protocols. Three years after treatment, the patient experienced chemotherapy-induced late effects (chronic heart disease) that hindered personal care, social activities and job opportunities and required follow-up. Stigmatization by the community burdened his family life and marital prospects. This case report is one of the first that testifies of combined medical and psychosocial challenges that childhood cancer survivors may face in sub-Saharan Africa and underlines the need for a holistic approach.
在肯尼亚等低收入和中等收入国家,儿童癌症存活率正在上升,这带来了一个新的医疗挑战:后期影响和幸存者的生活质量。研究了一个案例,描述了一名肯尼亚霍奇金淋巴瘤幸存者,说明了一些癌症儿童幸存者在肯尼亚的困难。探讨了治疗、污名化和重新融入社会的后期影响。研究人员审查了医疗记录,并使用半结构化访谈和社会影响量表进行污名评估。幸存者在接受ABVD和抢救方案治疗期间出现严重肺动脉高压。治疗三年后,患者出现化疗引起的晚期影响(慢性心脏病),阻碍了个人护理、社交活动和工作机会,需要随访。社会的污名化给他的家庭生活和婚姻前景带来了负担。这份病例报告是第一份证明撒哈拉以南非洲癌症儿童幸存者可能面临的医疗和心理社会综合挑战的报告之一,并强调需要采取全面的方法。
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引用次数: 0
The Attitude of Older Patients to Deprescribing Polypharmacy in Ogun State, Nigeria 尼日利亚奥贡州老年患者对复方处方的态度
Pub Date : 2022-12-23 DOI: 10.30442/ahr.0804-07-182
S. Saka, DO Odueke, O. Odusan, O. Oyinloye, O. Okunye
Background: Deprescribing has been suggested as a beneficial intervention to reduce polypharmacy among older patients. However, little is known about the willingness to accept this intervention among patients in resource-limited settings.Objective: To evaluate the attitudes of older patients to deprescribing polypharmacy.Methods: A quantitative, cross-sectional survey was carried out among consecutively selected ambulatory patients aged ≥65 years who were on ≥5 chronic medications in two secondary healthcare facilities in Ogun State, southwest Nigeria. The 22-item revised Patients Attitude Towards Deprescribing questionnaire was used to evaluate the participants' attitudes toward deprescribing, while another ten-question tool explored participants' sociodemographic and clinical data. Logistic regression was used to determine factors associated with willingness to deprescribe among the participants using the global question, "If my doctor said it was possible, I would be willing to stop one or more of my regular medicines”.Results: Out of the 341 participants, the majority were females (60.7%), and 90.0% were on 5-7 medications. About three-quarters (71.8%) strongly agreed or agreed that they would be willing “to stop one or more of their medicines if the doctor said it was possible”. Female gender and caregivers’ involvement in medication management were significantly associated with participants' willingness to accept deprescribing (p = 0.07 and p = 0.01).Conclusions: Most participants were willing to accept the deprescribing of their medications. Female gender and caregivers’ involvement in medication management were predictive factors for the participants' willingness to accept deprescribing.
背景:减少处方被认为是减少老年患者多药的有益干预措施。然而,在资源有限的情况下,人们对患者接受这种干预的意愿知之甚少。目的:了解老年患者对复方用药的态度。方法:在尼日利亚西南部奥贡州的两家二级医疗机构连续选择年龄≥65岁且服用≥5种慢性药物的门诊患者进行定量横断面调查。修订后的22项“患者减药态度问卷”用于评估参与者对减药的态度,而另一个10个问题的工具用于调查参与者的社会人口学和临床数据。研究人员使用逻辑回归来确定参与者是否愿意放弃处方的相关因素,并使用了一个全球性的问题,“如果我的医生说有可能,我愿意停止服用一种或多种常规药物”。结果:在341名参与者中,大多数是女性(60.7%),90.0%的人服用5-7种药物。大约四分之三(71.8%)的人强烈同意或同意“如果医生说可能的话”,他们愿意停止使用一种或多种药物。女性和照顾者参与药物管理与被试接受处方的意愿显著相关(p = 0.07和p = 0.01)。结论:大多数参与者愿意接受药物的处方化。女性性别和照顾者参与药物管理是受试者愿意接受处方的预测因素。
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引用次数: 1
Secondary hypothyroidism following the Resolution of Graves’ Disease: A Case Report Graves病消退后继发甲状腺功能减退1例
Pub Date : 2022-12-23 DOI: 10.30442/ahr.0804-09-184
Y. Lawal, YS Kaoje, IK Bansi
This is the case report of a 39-year-old lady who presented with clinical and laboratory features of secondary hypothyroidism two years after achieving clinical and biochemical resolution of Graves' disease and cessation of anti-thyroid medications. The thyroid function tests at presentation revealed: Serum T3 1.33ng/ml (normal range 0.8-1.7ng/ml), Serum T4 2.92 (normal range 4.5-12.0µg/dl), and TSH 0.2mIU/l (normal range 0.5-5.0mIU/l). Thyroid-related autoantibodies could not be assayed in the patient due to financial constraints. However, pointers to the possible autoimmune nature of secondary hypothyroidism include the recurrence of exophthalmos, dating of symptoms back to puerperium, relative lymphocytosis, and moderately elevated erythrocyte sedimentation rate (ESR). The patient was subsequently placed on levothyroxine and low-dose steroids, and the patient achieved clinical and biochemical euthyroidism in the sixth, ninth, and twelfth months of follow-up. This report is to demonstrate the development of secondary hypothyroidism following Graves' disease, and it also serves to highlight the judicious use of clinical acumen in the face of limited laboratory support to diagnose and treat endocrine disorders in resource-poor settings.
这是一位39岁的女性的病例报告,她在Graves病的临床和生化解决以及停止抗甲状腺药物治疗两年后,出现了继发性甲状腺功能减退的临床和实验室特征。介绍时的甲状腺功能测试显示:血清T3 1.33ng/ml(正常范围0.8-1.7ng/ml),血清T4 2.92(正常范围4.5-12.0µg/dl)和TSH 0.2mIU/l(正常范围0.5-5.0mIU/l)。由于经济限制,无法检测患者的甲状腺相关自身抗体。然而,继发性甲状腺功能减退可能具有自身免疫性,包括眼球突出复发、症状可追溯到产褥期、相对淋巴细胞增多和红细胞沉降率(ESR)适度升高。患者随后接受了左甲状腺素和低剂量类固醇治疗,患者在随访的第六、第九和第十二个月内实现了临床和生化甲状腺功能亢进。本报告旨在证明Graves病后继发性甲状腺功能减退症的发展,并强调在资源匮乏的环境中,在实验室支持有限的情况下,明智地使用临床智慧来诊断和治疗内分泌紊乱。
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引用次数: 0
Legalisation and Liberalisation of Cannabis: The Benefits and Drawbacks of the Global Trend 大麻的合法化和自由化:全球趋势的利弊
Pub Date : 2022-09-07 DOI: 10.30442/ahr.0803-01-168
OA Fasesan
Cannabis sativa is a complex domesticated plant that has an unstable taxonomy. It is the most utilised illicit substance that has gained prominence in some parts of the world as it is used for therapeutic and recreational purposes. C. Sativa has also been used to manage numerous medical conditions since antiquity. The pharmacological benefits of C. sativa are still subject to intense research due to inconsistent outcomes. C. sativa, like other psychoactive substances, has both medical and psychological side effects. Despite the lack of knowledge, medical practitioners continue to recommend this substance. This review aims to highlight the effects of legalisation and liberalisation on the global trend of cannabis use. A search was conducted on Google Scholar and Medline from 2012 to date. The results showed that cannabis was found to be effective in the management of some medical conditions, though more work is required. Recreational use is rising due to a reduced perception of harm and the availability of more potent species. Cannabis use persists despite the several medical and psychological side effects. It is concluded that there is a shortage of information on the safety and pharmacological properties of C. sativa, and more work is required.
大麻是一种复杂的驯化植物,其分类学不稳定。它是利用率最高的非法物质,在世界一些地区因其用于治疗和娱乐目的而备受关注。C.自古以来,萨蒂瓦也被用来治疗许多疾病。由于结果不一致,紫花苜蓿的药理作用仍有待深入研究。C.sativa和其他精神活性物质一样,具有医疗和心理双重副作用。尽管缺乏相关知识,但医生仍继续推荐使用这种物质。这篇综述旨在强调合法化和自由化对全球大麻使用趋势的影响。从2012年至今,在谷歌学者和Medline上进行了搜索。研究结果表明,大麻被发现在治疗某些疾病方面是有效的,尽管还需要做更多的工作。由于人们对伤害的感知减少,以及更强大的物种的可用性,娱乐用途正在增加。尽管存在一些医疗和心理副作用,但大麻的使用仍然存在。结论是,关于苜蓿的安全性和药理特性的信息不足,需要做更多的工作。
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引用次数: 0
Effect of Intramuscular Hyoscine-N-Butyl Bromide on Tubal Spasm and Pain Perception in Women with Infertility Undergoing Hysterosalpingography: A Randomised Controlled Trial 肌注海莨菪碱-正丁基溴对接受子宫输卵管造影的不孕妇女输卵管痉挛和疼痛感知的影响:一项随机对照试验
Pub Date : 2022-09-07 DOI: 10.30442/ahr.0803-04-171
P. Oriji, E. Kiridi, E. Kiridi, AE Ubom, J. Ugwoegbu, P. Bosrotsi, I. Abasi
Background: A tubal patency test is essential in evaluating women with infertility. Hysterosalpingography (HSG) is the investigation of choice for assessing tubal patency.Objective: To evaluate the effect of intramuscular hyoscine-N-butyl bromide on tubal spasms and pain perception during hysterosalpingography.Methods: This randomized, controlled trial was conducted at the Radiology Departments and Infertility Clinics of four health institutions in Bayelsa State, Nigeria, between January 2021 and April 2022. Five hundred and twenty infertile women undergoing hysterosalpingography were randomized into two groups. Women in group I (control) received a placebo, while women in Group II (experimental) received 20 mg of intramuscular hyoscine-N-butyl bromide. Pain scores at different steps of the procedure were recorded.Results: The overall mean pain scores progressively decreased from contrast instillation (4.97 ± 2.08) through 30-minutes post-procedure (3.54 ± 1.54) to 24 hours post-procedure (1.96 ± 1.78). Pain scores at contrast instillation, 30 minutes and 24 hours after HSG were significantly lower in the hyoscine group compared to the placebo group (p = 0.001 each). There were significantly fewer women with tubal blockage in the hyoscine group compared to the placebo group [78 (30.0%) vs 131 (50.4%); p = 0.001].Conclusion: Intramuscular hyoscine-N-butyl bromide before hysterosalpingography significantly reduces pain and tubal spasm during the procedure.
背景:输卵管通畅性检查对评估不孕妇女至关重要。子宫输卵管造影术(HSG)是评估输卵管通畅性的首选检查方法。目的:评价肌内注射正丁基溴化舌骨素对子宫输卵管造影术中输卵管痉挛和疼痛感觉的影响。方法:这项随机对照试验于2021年1月至2022年4月在尼日利亚巴耶尔萨州四家卫生机构的放射科和不孕不育诊所进行。520名接受子宫输卵管造影的不孕妇女被随机分为两组。第一组(对照组)的妇女接受安慰剂治疗,而第二组(实验组)的女性接受20 mg肌肉注射的鱼骨素-N-丁基溴化物治疗。记录手术不同步骤的疼痛评分。结果:从造影剂滴注(4.97±2.08)到术后30分钟(3.54±1.54)再到术后24小时(1.96±1.78。与安慰剂组相比,鱼肝素组输卵管堵塞的女性明显减少[78(30.0%)vs 131(50.4%);p=0.001]。结论:子宫输卵管造影前肌注鱼肝素-N-丁基溴化物可显著减轻手术过程中的疼痛和输卵管痉挛。
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引用次数: 0
A Bibliometric Analysis of Health and Medicine Research in Uganda 乌干达卫生和医学研究的文献计量学分析
Pub Date : 2022-09-07 DOI: 10.30442/ahr.0803-03-170
A. Kasule, B. Mutebi, A. Ssentumbwe
Background: Research is one of the many domains that help countries to provide solutions to various challenges and improve facilities. The bibliometric analysis measures the research output of individuals/research teams, institutions, and countries and identifies national and international research networks across the globe.Objective: To examine key research topics, interrelations, and collaboration patterns of published health-related research in Scopus from Ugandan institutions and authors.Methods: Using the search term "Uganda, health, medicine" in the title, abstract and keywords, documents published between 1963 and 2022 were retrieved from Scopus. The extracted records were analysed in terms of keywords analysis and collaboration networks. The R Bibliometrics package was used to analyse and visualise the data.Results: The results reveal to scholars and practitioners the most relevant authors, affiliations, publication sources, trends in research topics and collaborating countries. The results provide valuable information for more investigation into the revealed research trends.Conclusion: Bibliometric analysis of health research in Uganda revealed that the most frequent topics are medicinal plants, traditional medicine and herbal medicine. Research work on malaria, Covid-19 and HIV/AIDS is also evident. There is a significant research collaboration with authors from the United States and the United Kingdom.
背景:研究是帮助各国解决各种挑战和改善设施的众多领域之一。文献计量分析衡量个人/研究团队、机构和国家的研究成果,并确定全球的国家和国际研究网络。目的:研究乌干达机构和作者在Scopus发表的健康相关研究的关键研究主题、相互关系和合作模式。方法:在标题、摘要和关键词中使用搜索词“乌干达、健康、医学”,从Scopus检索1963年至2022年间发表的文献。对提取的记录进行了关键词分析和协作网络分析。R Bibliometrics软件包用于分析和可视化数据。结果:研究结果向学者和从业者揭示了最相关的作者、隶属关系、出版物来源、研究主题和合作国家的趋势。研究结果为进一步调查所揭示的研究趋势提供了有价值的信息。结论:乌干达健康研究的文献计量分析显示,最常见的主题是药用植物、传统医学和草药。关于疟疾、新冠肺炎和艾滋病毒/艾滋病的研究工作也很明显。与美国和英国的作者进行了重要的研究合作。
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