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Sarcoma Botryoides of the Bladder in a Nigerian Child: A Case Report 尼日利亚儿童膀胱肉毒杆菌肉瘤一例报告
Pub Date : 2022-06-01 DOI: 10.30442/ahr.0802-07-166
A. Oladimeji, G. Akinyosoye, A. Solarin, A. Ayodele, M. Abdulsalam, F. Njokanma
Sarcoma botryoides of the bladder is a variant of the embryonal form of rhabdomyosarcoma that is characterized by protrusion of tumour cells and stroma into a body cavity like a bunch of grapes. Apart from the bladder, the embryonal form of this tumour can occur in other areas such as the vagina, nasopharynx, middle ear and common bile duct. One of its complications is obstruction of the bladder outlet, presenting as acute urinary retention and acute kidney injury. Pressure on the adjacent tissues and organs is also well recognized. It has an intermediate prognosis which depends on age, site and the extent of disease at diagnosis. We report a case of sarcoma botryoides in a 3-year-old Nigerian girl, confirmed by imaging and histology.
膀胱肉瘤是胚胎型横纹肌肉瘤的一种变体,其特征是肿瘤细胞和基质像一串葡萄一样突出到体腔中。除了膀胱,这种肿瘤的胚胎形式也可以发生在其他部位,如阴道、鼻咽、中耳和总胆管。其并发症之一是膀胱出口梗阻,表现为急性尿潴留和急性肾损伤。对邻近组织和器官的压力也得到了很好的认识。它具有中等预后,这取决于年龄、部位和诊断时的疾病程度。我们报告了一例3岁尼日利亚女孩的肉毒杆菌样肉瘤,经影像学和组织学证实。
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引用次数: 0
A Facility-Based Survey of Maternal Anti-Tetanus Vaccination Schedule Completion in a Nigerian University Community 尼日利亚大学社区孕产妇抗破伤风疫苗接种计划完成情况的设施调查
Pub Date : 2022-06-01 DOI: 10.30442/ahr.0802-06-165
J. Imaralu, A. Adekoya, A. Akadri, F. Bamidele, CC Nwankpa, J. Sotunsa
Background: Maternal anti-tetanus vaccination is required to prevent maternal and neonatal tetanus. In the absence of lifetime protective dosing, repeat vaccination in every new pregnancy is needed to achieve protection of the newborn against tetanus. Objectives: To determine maternal anti-tetanus vaccination schedule completion rates and the reasons for non-completion of the schedule. Methods: This cross-sectional survey was conducted among Nigerian antenatal clinic attendees using an interviewee-administered questionnaire. Results: Most (291/347; 83.9%) respondents had received a TT vaccine in the index pregnancy, and 280/347 (80.7%) received their first TT injection at the booking visit. In comparison, 202/238 (84.9%) of those eligible had received tetanus toxoid protective immunisation (TTPDI) in the index pregnancy. Although a majority (301/347; 86.7%) of the respondents had received at least a dose of TT in a previous pregnancy, only 23/246 (9.3%) eligible pregnant women had received complete vaccination (TT5) Parity (p<0.001) and ethnicity (0.013) were the main determinants of the maternal tetanus vaccination schedule (TT5) completion. However, the socio-demographic characteristics were similar for TTPDI. The commonest reason for non-completion was forgetfulness 172/218 (78.9%), and most (287/347; 89.1%) of the respondents wished to receive telephone reminders. Conclusions: Although neonatal tetanus protective dosing of TT in the current pregnancy was high, a low proportion of mothers completed the five doses recommended by the WHO for lifetime immunity.
背景:预防产妇和新生儿破伤风需要接种产妇抗破伤风疫苗。在没有终身保护性剂量的情况下,需要在每次新妊娠中重复接种疫苗,以实现对新生儿的破伤风保护。目的:了解产妇破伤风疫苗接种计划完成率及未完成计划的原因。方法:这个横断面调查是在尼日利亚产前诊所的与会者中进行的,使用受访者管理的问卷。结果:大多数(291/347;83.9%的应答者在指数妊娠期间接种了TT疫苗,280/347(80.7%)在预约就诊时首次接种了TT疫苗。相比之下,202/238(84.9%)符合条件的人在指数妊娠期间接受了破伤风类毒素保护性免疫接种(TTPDI)。虽然多数(301/347;86.7%的应答者在以前的妊娠中至少接受过一剂破伤风疫苗接种,只有23/246(9.3%)符合条件的孕妇接受了完整的疫苗接种(TT5)。胎次(p<0.001)和种族(0.013)是孕产妇破伤风疫苗接种计划(TT5)完成的主要决定因素。然而,TTPDI的社会人口学特征相似。最常见的不完成原因是健忘172/218(78.9%),最多(287/347;89.1%)受访者希望收到电话提醒。结论:尽管在当前妊娠期接种破伤风疫苗的新生儿保护剂量很高,但完成世卫组织推荐的五剂终身免疫接种的母亲比例很低。
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引用次数: 0
Perceptions and Experiences of Physical Violence Among Public Secondary School Students in Lagos State 拉各斯州公立中学学生对身体暴力的认知和经历
Pub Date : 2022-06-01 DOI: 10.30442/ahr.0802-01-160
A. Ogunyemi, A. Abiola, T. Olufunlayo, OP Ogunnubi, A. Onajole
Background: Physical violence (PV) in secondary schools is an apparent challenge that requires urgent attention because of its adverse outcomes. It has led to the destruction of school properties and disruption of teaching and learning, thus resulting in poor academic grades and even death. Objectives: To assess the perceptions and experiences of physical violence among selected senior secondary students in Lagos State. Methods: The study utilised a cross-sectional design with a multistage sampling technique to recruit respondents from four secondary schools in Lagos State. Data were collected using a self-administered questionnaire adapted from the Global School Health Survey and the Youth Risk Behaviour Survey (GSHS, 2004). Results: Majority (82.7%) of the respondents had correct knowledge of the health consequences of youth violence, and 78.3% knew that both victims and perpetrators are at risk of injury or death. About 62.5% agreed that youth violence is an essential issue in adolescence, and 85.2% favoured administrative sanctions against offenders. Violent acts such as physical attacks were experienced by 40.7%, while 42.2% and 7.7% experienced physical fights and belonged to a school gang. Involvement in a physical fight was significantly associated with belonging to a school gang (p<0.001) and being a victim of bullying (p<0.001). Conclusion: Physical violence is a common behaviour among senior secondary school students. Belonging to a gang and being a victim of bullying was associated with physical violence. Targeted education on avoiding physical violence and risky behaviours is recommended in schools.
背景:中学中的身体暴力(PV)是一个明显的挑战,由于其不良后果,需要紧急关注。它导致学校财产被毁,教学中断,从而导致学习成绩不佳甚至死亡。目的:评估拉各斯州选定高中生对身体暴力的看法和经历。方法:该研究采用多阶段抽样技术的横断面设计,从拉各斯州的四所中学招募受访者。数据是使用改编自全球学校健康调查和青年风险行为调查的自填问卷收集的(GSHS,2004年)。结果:大多数(82.7%)受访者对青少年暴力的健康后果有正确的认识,78.3%的受访者知道受害者和施暴者都有受伤或死亡的风险。约62.5%的人同意青少年暴力是青春期的一个重要问题,85.2%的人赞成对罪犯进行行政制裁。40.7%的人经历过身体攻击等暴力行为,42.2%和7.7%的人经历了肢体冲突,属于学校帮派。参与肢体冲突与加入学校帮派(p<0.001)和成为欺凌受害者(p<0.001)显著相关。结论:肢体暴力是高中生的常见行为。加入帮派并成为欺凌的受害者与身体暴力有关。建议在学校进行有针对性的教育,避免身体暴力和危险行为。
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引用次数: 0
Acute Uterine Inversion Complicating Mid-Trimester Unsafe Abortion in a Teenage Nigerian Girl 尼日利亚一名少女急性子宫反转合并中期不安全流产
Pub Date : 2022-03-25 DOI: 10.30442/ahr.0801-08-159
S. Nyeche, A. Ubom
Uterine inversion is a rare but life-threatening obstetric emergency, complicating 1 in 2,000 to 1 in 50,000 deliveries. Very rarely, this condition also complicates unsafe abortion. A case of acute complete (fourth-degree) uterine inversion, with gangrene of the uterus in an 18-year-old nulliparous girl who presented to the Gynaecologic Emergency Unit of the University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria, in hypovolemic shock from massive haemorrhage following unsafe mid-trimester termination of unwanted pregnancy is reported. She was adequately resuscitated, and a vaginal hysterectomy was performed. The patient was discharged following an uneventful postoperative period. This case highlights the consequences of the high unmet need for family planning and the restrictive abortion laws in Nigeria, limiting access to effective contraception and safe abortion services, thereby increasing the risk of maternal mortality and morbidity from complications of unsafe abortion
子宫内翻是一种罕见但危及生命的产科紧急情况,每2000到50000次分娩中就有1次发生子宫内翻。这种情况很少会使不安全的堕胎变得复杂。据报道,尼日利亚哈科特港哈科特港大学教学医院妇科急诊室的一名18岁未产妇因意外妊娠中期不安全终止后大出血引发低血容量性休克,导致急性完全(四度)子宫内翻并子宫坏疽。她得到了充分的复苏,并进行了阴道子宫切除术。病人在平静的术后出院。这起案件突显了计划生育需求未得到满足以及尼日利亚限制性堕胎法的后果,限制了获得有效避孕和安全堕胎服务的机会,从而增加了产妇因不安全堕胎并发症而死亡和发病的风险
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引用次数: 0
Ovarian and uterine functions in female albino rats fed dietary meal supplemented with Mucuna pruriens (L.) DC. seed powder 雌性白化大鼠的卵巢和子宫功能,喂食补充了瘙痒性粘液(L.)DC的膳食。种子粉
Pub Date : 2022-03-25 DOI: 10.30442/ahr.0801-02-153
J. Ashidi, F. Owagboriaye, O. I. Lawal, P. Houghton, T. Efferth
Background: While the reproduction-enhancing property of Mucuna pruriens (MP) seed has been widely studied in males, little is known about this property in females despite the rate at which the seed is consumed by both sexes worldwide. Objective: To determine the effect of MP seed powder in dietary inclusion on ovarian and uterine functions of adult female albino rats. Methods: The rats were randomised into four groups. Group 1 (Control) was given standard rat chow (15g of feed/rat/day only) while groups 2, 3 and 4 were fed diets supplemented with MP seed powder at 0.75 g, 1.5g and 2.25g/day, respectively, for 12 weeks. Serum levels of oestradiol, follicle stimulating hormone, luteinising hormone, ovarian Δ5, 3β- hydroxysteroid dehydrogenase (Δ5, 3β-HSD) and 17 β hydroxysteroid dehydrogenase (17β-HSD) activities, ovarian and uterine peroxidase and tissue cytoarchitectural structures were used as diagnostic markers of reproductive function. Results: Significant increases in the serum level of all hormones including ovarian Δ5, 3β-HSD, 17β-HSD activities, ovarian and uterine peroxidase activities, and improvement of the ovarian and uterine cytoarchitectural integrity of the rats fed MP at 0.75g/day compared to other groups were observed. However, MP at 2.25g/day induced reproductive dysfunction characterised by significant reductions in hormones, uterine and ovarian enzyme activities, severe degenerative cytoarchitectural lesions in tissues. Conclusions: MP seed improves uterine and ovarian functions at a dose level of 0.75g/day, but a higher dose value may be toxic.
背景:虽然人们已经在雄性中广泛研究了痒鼠(MP)种子的繁殖增强特性,但人们对雌性的这种特性知之甚少,尽管全世界两性都在消耗这种种子。目的:探讨MP籽粉对成年雌性白化大鼠卵巢和子宫功能的影响。方法:将大鼠随机分为四组。第1组(对照组)给予标准大鼠饲料(仅15g饲料/只大鼠/天),而第2、3和4组则分别以0.75g、1.5g和2.25g/天的MP籽粉补充日粮,为期12周。血清雌二醇、卵泡刺激素、黄体生成素、卵巢Δ5、3β-羟基类固醇脱氢酶(Δ5,3β-HSD)和17β-羟基甾体脱氢酶(17β-HSD。结果:与其他组相比,喂食0.75g/天MP的大鼠血清中所有激素水平均显著升高,包括卵巢Δ5、3β-HSD、17β-HSD活性、卵巢和子宫过氧化物酶活性,以及卵巢和子宫细胞结构完整性的改善。然而,2.25g/天的MP诱导生殖功能障碍,其特征是激素、子宫和卵巢酶活性显著降低,组织中出现严重的退行性细胞结构损伤。结论:在0.75g/天的剂量水平下,MP种子可以改善子宫和卵巢功能,但较高的剂量值可能具有毒性。
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引用次数: 0
Carotid Doppler Ultrasonography in Patients with Co-existing Type 2 Diabetes Mellitus and Hypertension in Nigeria 尼日利亚合并2型糖尿病和高血压患者的颈动脉多普勒超声检查
Pub Date : 2022-03-25 DOI: 10.30442/ahr.0801-05-156
Abiola O. Adekoya, A. Olatunji, Adeyanju Akinola, O. Odunsan, A. Adekoya, O. Olawale
Background: The co-existence of diabetes mellitus (DM) and hypertension (HTN) has been rising globally with subclinical atherosclerotic complications. These vascular changes can be detected using carotid ultrasonography. Objectives: To determine and compare the carotid arterial structural wall changes and blood flow velocities of adults with co-existing DM and HTN with age- and sex-matched non-diabetic, non-hypertensive controls. Methods: A cross-sectional comparative study of 300 participants comprising 200 adults with co-existing DM and HTN and 100 age- and sex-matched controls was done. Their carotid arteries were examined bilaterally for plaques, carotid intima media thickness (CIMT) and flow velocities – peak systolic velocity (PSV), end diastolic velocity (EDV), pulsatility index (PI) and resistive index (RI) using 4–12MHz linear array transducer. Visceral obesity and serum lipids were also assessed. Results: The mean age of the subjects was 56.13 ± 6.93 years; they comprised 38% males and 62% females. The subjects’ CIMT was statistically significantly higher (p = 0.001) with a three-fold mean increase (45.5%) compared to the controls (13.7%). Lower flow velocities but higher indices were also observed in the subjects. Strong and significant correlations were observed between EDV and PI (r =-0.663, p =>0.001), EDV and RI (r = -0.661, p =>0.001) and PI and RI (r =0.988, p = >0.001) among the subjects. Conclusion: Significant reduction in flow velocities with increased CIMT may be an early indication of subclinical atherosclerosis. Therefore, carotid ultrasonography should be mandatory in individuals at risk for early detection and possible prevention of atherosclerotic complications.
背景:糖尿病(DM)和高血压(HTN)的并发亚临床动脉粥样硬化并发症在全球范围内呈上升趋势。这些血管变化可以通过颈动脉超声检测到。目的:确定并比较同时患有糖尿病和高血压肾病的成年人与年龄和性别匹配的非糖尿病、非高血压对照组的颈动脉结构壁变化和血流速度。方法:对300名参与者进行横断面比较研究,其中包括200名同时患有糖尿病和HTN的成年人和100名年龄和性别匹配的对照组。使用4–12MHz线性阵列换能器对他们的颈动脉进行双侧斑块、颈动脉内膜-中膜厚度(CIMT)和流速——收缩峰值速度(PSV)、舒张末期速度(EDV)、搏动指数(PI)和阻力指数(RI)检查。还评估了内脏肥胖和血脂。结果:受试者的平均年龄为56.13±6.93岁;其中男性占38%,女性占62%。受试者的CIMT在统计学上显著较高(p=0.001),与对照组(13.7%)相比,平均增加了三倍(45.5%)。受试者流速较低,但指数较高。在受试者中,EDV和PI(r=-0.663,p=0.001)、EDV和RI(r=-0.661,p=0.001)以及PI和RI(r=0.988,p=0.001。结论:随着CIMT的增加,流速显著降低可能是亚临床动脉粥样硬化的早期迹象。因此,颈动脉超声检查应该是有风险的个体的强制性检查,以早期发现并可能预防动脉粥样硬化并发症。
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引用次数: 1
Predictors of COVID-19 Vaccine Acceptance Among Nigerian Medical Doctors 尼日利亚医生对COVID-19疫苗接受度的预测因素
Pub Date : 2022-03-25 DOI: 10.30442/ahr.0801-01-152
CA Nri-Ezedi, C. Okechukwu, OC Ofiaeli, E. Nwaneli, S. Musa, I. Kida, H. Adetola, T. Ulasi
Background: Since its discovery in late 2019, COVID-19 has claimed approximately three million lives worldwide, causing a significant economic burden and strain on health care delivery and services. Therefore, the COVID-19 vaccine may offer the potential to promote global recovery. Objective: To determine the acceptability of the COVID-19 vaccine among Nigerian doctors and the factors influencing the acceptance. Methods: Using a cross-sectional design, an anonymous online survey was administered to medical doctors across the six geopolitical zones in Nigeria between 13 January and 31 January 2021, using the health belief model (HBM). Results: Out of 830 respondents, 38.8% were willing to take the COVID-19 vaccine, 36.0% were unsure, while the remaining 26.5% refused to take the vaccine. Following adjustments, males were more likely to take the vaccine (OR = 3.357; 95% CI 2.009-5.610; p = 0.0001), whereas increasing age, higher perceived viral virulence and perceived viral infectivity were observed to be significantly associated with less likelihood of accepting the vaccine. Respondents who believed in the efficacy of ivermectin were much less likely to receive the vaccine (OR = 0.217; 95% CI 0.108-0.436; p = 0.001). Concerns on vaccination safety were the main barriers to vaccine acceptability. Hypothetically addressing these concerns increased vaccine acceptance rates by approximately a third (34.6%) (p < 0.001). Conclusion: The proposed nationwide distribution of the COVID-19 vaccine may be met with poor vaccine acceptability among Nigerian medical practitioners. Measures specifically addressing vaccine safety concerns should be provided to allay fears and enhance the acceptability of the vaccine.
背景:自2019年末发现以来,新冠肺炎已在全球夺走约300万人的生命,给医疗保健提供和服务带来了巨大的经济负担和压力。因此,新冠肺炎疫苗可能提供促进全球复苏的潜力。目的:确定新冠肺炎疫苗在尼日利亚医生中的可接受性及其影响因素。方法:使用横断面设计,在2021年1月13日至1月31日期间,使用健康信念模型(HBM)对尼日利亚六个地缘政治地区的医生进行了匿名在线调查。结果:830名受访者中,38.8%的人愿意接种新冠肺炎疫苗,36.0%的人不确定,其余26.5%的人拒绝接种。调整后,男性更有可能接种疫苗(OR=3.357;95%CI2.009-5.610;p=0.0001),而年龄增加、感知病毒毒力和感知病毒传染性较高与接受疫苗的可能性降低显著相关。相信伊维菌素有效性的受访者接种疫苗的可能性要小得多(OR=0.217;95%CI 0.108-0.436;p=0.001)。对疫苗接种安全性的担忧是疫苗可接受性的主要障碍。假设解决这些问题使疫苗接受率提高了约三分之一(34.6%)(p<0.001)。结论:拟议的新冠肺炎疫苗全国分发可能会遇到尼日利亚医生对疫苗接受率低的问题。应提供专门解决疫苗安全问题的措施,以减轻恐惧,提高疫苗的可接受性。
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引用次数: 1
Knowledge of COVID-19, Use of Personal Protective Equipment and Other Safety Practices of Healthcare Workers in Southwest Nigeria 尼日利亚西南部医护人员的新冠肺炎知识、个人防护设备的使用和其他安全实践
Pub Date : 2022-03-25 DOI: 10.30442/ahr.0801-03-154
T. Ojo, O. Fajobi, A. Babatola, Morenike Akinolosotu, O. Esan, T. Adetunji, A. Onayade
Background: Healthcare workers have a higher risk of SARS CoV2 infection with implications for transmission of infection and the safety of workers and patients. Objective: To assess knowledge on COVID-19 and the safety practices among selected healthcare workers in southwest Nigeria. Methods: A cross-sectional study of 210 workers providing direct care to patients during the COVID-19 pandemic was conducted. Respondents were recruited through simple random sampling of members of online platforms of healthcare workers in Osun, Ondo and Ekiti States. Information on sociodemographic characteristics, knowledge of PPE and safety practices was obtained through a close-ended questionnaire. Results: The mean age of the respondents was 36.5±7.5 years. About 29% and 30% of respondents were from the State and Federal Government-owned Teaching Hospitals, respectively. A little above half (58.1%) had good knowledge of COVID-19, while 62.1% used PPE always when attending to suspected COVID19 cases. More than half (53.8%) had been trained on infection prevention and control (IPC), but only 34.3% adhered to good safety practices. Healthcare workers in State government-owned teaching hospitals had lower odds of good safety practices than those in Federal Teaching Hospitals (OR = 0.42, 95% CI = 0.19-0.93, p = 0.031). Conclusion: The knowledge of appropriate PPE and practice of safety precautions among healthcare workers is sub-optimal. This may predispose to increased COVID-19 transmission among healthcare workers, patients, and their families. Training and retraining healthcare workers, especially those from hospitals identified by the study as having poor safety practices, should be encouraged.
背景:卫生保健工作者感染SARS CoV2的风险较高,这对感染的传播以及工作人员和患者的安全具有影响。目的:评估尼日利亚西南部部分卫生保健工作者对COVID-19的知识和安全做法。方法:对COVID-19大流行期间直接护理患者的210名工作人员进行横断面研究。答复者是通过简单随机抽样从奥孙州、翁多州和埃基蒂州的保健工作者在线平台成员中招募的。通过封闭式问卷获得了关于社会人口特征、个人防护装备知识和安全做法的信息。结果:调查对象平均年龄为36.5±7.5岁。大约29%和30%的受访者分别来自州和联邦政府拥有的教学医院。略高于一半(58.1%)的人对新冠肺炎有良好的了解,62.1%的人在照顾疑似病例时总是使用个人防护装备。一半以上(53.8%)接受过感染预防和控制(IPC)培训,但只有34.3%遵守了良好的安全规范。州立公立教学医院的医护人员获得良好安全操作的几率低于联邦教学医院的医护人员(OR = 0.42, 95% CI = 0.19-0.93, p = 0.031)。结论:卫生保健工作者对适当的个人防护装备的知识和安全预防措施的实践是次优的。这可能会增加COVID-19在医护人员、患者及其家属之间的传播。应该鼓励对卫生保健工作者进行培训和再培训,特别是那些来自该研究确定安全措施较差的医院的卫生保健工作者。
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引用次数: 0
Alterations in Haematological and Clotting Profile of Post-Menopausal Women in Benin City, Nigeria 尼日利亚贝宁市绝经后妇女血液学和凝血特征的改变
Pub Date : 2022-03-25 DOI: 10.30442/ahr.0801-04-155
Mabel Iyobo Ebengho, P. A. Obazelu, Mathias Abiodun Emokpae
Background: The cessation of ovarian functions at menopause and the accompanying decline in the production of ovarian steroid hormones creates a unique set of health concerns for women. Reductions in sex steroid levels, particularly oestrogen, have been associated with various diseases and conditions, including bleeding disorders, coronary heart disease (CHD), osteoporosis, cognitive dysfunction, urinary incontinence, hot flushes, and mood changes, among others. Objective: To determine changes in haemorheological and clotting profile in post-menopausal women. Methods: Two hundred participants comprising one hundred and fifty post-menopausal women and fifty healthy pre-menopausal control subjects were studied. The investigations carried out include whole blood viscosity, plasma viscosity, fibrinogen concentration, Prothrombin time (PT), Activated partial thromboplastin time with kaolin (APTTK) levels and complete blood count using standard methods. Results: The mean age (p = 0.01), platelet count (p = 0.013), neutrophil (p = 0.03), neutrophil to lymphocyte ratio (p = 0.045) and platelet to lymphocyte ratio (p = 0.044) in postmenopausal women were significantly higher while lymphocyte count (p = 0.004) was significantly lower in postmenopausal compared to premenopausal women. Similarly, plasma oestradiol (p = 0.001), plasma viscosity (p = 0.03), relative blood viscosity (p = 0.03), whole blood viscosity (p = 0.03) and PTTK (p = 0.04) were significantly lower among postmenopausal women compared to premenopausal control subjects. Conclusion: Relative plasma viscosity correlated positively with age. There were significantly lower levels of haemorheological and clotting profile in post-menopausal women. These changes may be due to age or a decline in circulating oestrogen levels.
背景:绝经期卵巢功能的停止和伴随的卵巢类固醇激素产生的下降为妇女创造了一套独特的健康问题。性类固醇水平的降低,特别是雌激素水平的降低,与各种疾病和状况有关,包括出血性疾病、冠心病、骨质疏松症、认知功能障碍、尿失禁、潮热和情绪变化等。目的:了解绝经后妇女血液流变学和凝血状况的变化。方法:200名受试者,包括150名绝经后妇女和50名健康的绝经前对照组。使用标准方法进行的调查包括全血粘度、血浆粘度、纤维蛋白原浓度、凝血酶原时间(PT)、高岭土活化部分凝血活酶时间(APTTK)水平和全血细胞计数。结果:绝经后妇女的平均年龄(p = 0.01)、血小板计数(p = 0.013)、中性粒细胞(p = 0.03)、中性粒细胞/淋巴细胞比(p = 0.045)、血小板/淋巴细胞比(p = 0.044)显著高于绝经前妇女,淋巴细胞计数(p = 0.004)显著低于绝经前妇女。同样,与绝经前对照组相比,绝经后妇女的血浆雌二醇(p = 0.001)、血浆粘度(p = 0.03)、相对血液粘度(p = 0.03)、全血粘度(p = 0.03)和PTTK (p = 0.04)均显著降低。结论:血浆相对粘度与年龄呈正相关。绝经后妇女的血液流变学和凝血水平明显较低。这些变化可能是由于年龄或循环雌激素水平下降。
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引用次数: 1
Dietary Habits, Physical Activity and Sleep Pattern Among In-School Adolescents in Lagos, Nigeria 尼日利亚拉各斯在校青少年的饮食习惯、身体活动和睡眠模式
Pub Date : 2022-03-25 DOI: 10.30442/ahr.0801-06-157
I. Akinola, Babatunde A. Odugbemi, O. Bakare, O. Odusote, F. Njokanma
Background: Overnutrition has been documented at epidemic levels in children and adults. The associated risk factors may include poor dietary habits, sedentary behaviour, inadequate sleep and low parental education. Objective: To describe dietary habits, physical activity and sleep patterns among secondary school adolescents. Methods: A cross-sectional study of 1,120 adolescents recruited from public and private secondary schools in Lagos, Nigeria, was carried out to study the dietary habits, sleep patterns and physical activity in relation to nutritional status. Results: Ten per cent of the adolescents skipped breakfast, while 28% had fruits on up to five days of the week. Eleven per cent had a sweetened drink every day, while 20 % had a sweetened drink on most days of the week. One out of four (26%) adolescents had more than two hours of screen time daily, and only 5% engaged in sporting activities up to five times weekly. One-third of the students slept for less than six hours daily and experienced sleeping difficulties. Multivariate analysis showed that females were twice as likely not to participate in sports (OR = 2.38, CI = 1.3-4.37, p = 0.002 and to have a higher intake of confectionaries (OR = 1.47, CI = 1.07-2.04, p = 0.01. Conclusion: Poor dietary habits, inadequate physical activity and insufficient sleep were observed among secondary school adolescents. A multi-pronged approach to improve these behaviours is recommended.
背景:在儿童和成人中,营养过剩的流行程度已被记录在案。相关的风险因素可能包括不良的饮食习惯、久坐行为、睡眠不足和父母教育程度低。目的:描述中学生的饮食习惯、体育活动和睡眠模式。方法:对尼日利亚拉各斯公立和私立中学的1120名青少年进行横断面研究,研究饮食习惯、睡眠模式和体育活动与营养状况的关系。结果:10%的青少年不吃早餐,28%的青少年一周中有五天吃水果。11%的人每天喝一杯加糖饮料,20%的人在一周中的大部分时间都喝加糖饮料。四分之一(26%)的青少年每天的屏幕时间超过两小时,只有5%的青少年每周参加五次体育活动。三分之一的学生每天睡眠不足六个小时,并出现睡眠困难。多因素分析显示,女性不参加体育运动的可能性是女性的两倍(OR=2.38,CI=1.3-4.37,p=0.002),糖果摄入量更高(OR=1.47,CI=1.07-2.04,p=0.01)。结论:中学生饮食习惯差,体育活动不足,睡眠不足。建议采取多管齐下的方法来改善这些行为。
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引用次数: 2
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Annals of Health Research
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