Lancet Regional Health-Europe最新文献

{"title":"Sex differences in clinically diagnosed psychiatric disorders over the lifespan: a nationwide register-based study in Sweden.","authors":"Yihui Yang, Fang Fang, Filip K Arnberg, Ralf Kuja-Halkola, Brian M D'Onofrio, Henrik Larsson, Isabell Brikell, Zheng Chang, Ole A Andreassen, Paul Lichtenstein, Unnur A Valdimarsdóttir, Donghao Lu","doi":"10.1016/j.lanepe.2024.101105","DOIUrl":"10.1016/j.lanepe.2024.101105","url":null,"abstract":"<p><strong>Background: </strong>Limited studies exist on sex differences in incidence rates of psychiatric disorders across the lifespan. This study aims to analyze sex differences in the incidence rates of clinically diagnosed psychiatric disorders over the lifespan.</p><p><strong>Methods: </strong>We conducted a nationwide register-based cohort study, including all individuals who were born in Sweden and lived in Sweden between 2003 and 2019, including 4,818,071 females and 4,837,829 males. We calculated sex- and age-specific standardized incidence rates for any and 10 major types of psychiatric disorders. Multivariable-adjusted incidence rate differences (IRDs) for diagnosed psychiatric disorders between females and males were estimated.</p><p><strong>Findings: </strong>During a follow-up of 119,420,908 person-years, males showed a higher incidence rate of any diagnosed psychiatric disorder than females at age 5-9 (IRD = -8.93; 95% CI: -9.08 to -8.79; per 1000 person-years), whereas females showed a higher rate than males at age 15-19 (IRD = 9.33; 95% CI: 9.12-9.54) and onwards (except age 60-69). Specifically, among females, excess rates were apparent for depressive, anxiety, eating, stress-related and bipolar disorders at age 10-54, whereas among males, excess rates were pronounced for autism and attention deficit hyperactivity disorders before age 14, drug use disorders at age 15-54, and alcohol use disorders in adulthood. For schizophrenia, the male excess at age 15-49 shifted to female excess at age 60-79. The magnitude of IRDs were greater in recent years and individuals with lower socioeconomic status.</p><p><strong>Interpretation: </strong>Knowledge about the lifespan and socioeconomic variations in the sex differences in rates of diagnosed psychiatric disorders may inform targeted screening/intervention strategies.</p><p><strong>Funding: </strong>Vetenskapsrådet, FORTE, Karolinska Institutet Strategic Research Area in Epidemiology and Biostatistics, and Icelandic Research Fund.</p>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"101105"},"PeriodicalIF":13.6,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11670697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, predictors, and patterns of patient reported non-motor outcomes six months after stroke: a prospective cohort study","authors":"Hatice Ozkan ,&nbsp;Gareth Ambler ,&nbsp;Gargi Banerjee ,&nbsp;John J. Mitchell ,&nbsp;Carmen Barbato ,&nbsp;Simone Browning ,&nbsp;Alex P. Leff ,&nbsp;Robert J. Simister ,&nbsp;David J. Werring","doi":"10.1016/j.lanepe.2024.101080","DOIUrl":"10.1016/j.lanepe.2024.101080","url":null,"abstract":"<div><h3>Background</h3><div>Adverse non-motor outcomes have a major impact on patients and caregivers after stroke, but knowledge of their prevalence, predictors and patterns across multiple health domains remains limited; we therefore aimed to obtain these data in a large observational prospective cohort study.</div></div><div><h3>Methods</h3><div>We included data from the Stroke Investigation Group in North and Central London (SIGNAL) registry based at the University College London Hospitals (UCLH) Comprehensive Stroke Service which serves a multi-ethnic population of ∼1.6 million people. In adult patients diagnosed with acute stroke due to cerebral ischaemia or intracerebral haemorrhage (ICH) from January 2017 to January 2020 we evaluated non-motor outcomes (anxiety, depression, fatigue, sleep disturbance, social participation, pain, bowel dysfunction, bladder dysfunction, mood problems, communication problems, activities of daily living (ADL), memory and thinking problems) at 6-month follow-up. We evaluated baseline predictors in multivariable logistic regression, and correlations between domains using kappa statistics.</div></div><div><h3>Findings</h3><div>Follow-up was complete for 3080 of 3338 (92.3%) eligible surviving patients (2534 ischaemic stroke, 547 with ICH; mean age 71.2 years, 1379 (44.8%) female, 1774 (59.3%) white). The most prevalent adverse non-motor outcomes were fatigue 1756 (57%), reduced social participation 1694 (55%), sleep disturbance 1663 (54%), and constipation 1355 (44%). The rates of adverse non-motor outcomes in ⩾ 1, ⩾ 2, ⩾ 3, ⩾ 4, and ⩾ 5 domains were 2310 (75%), 1571 (51%), 1519 (49%), 1232 (40%), and 801 (26%), respectively. Factors associated with adverse non-motor outcomes included stroke due to ICH, stroke severity, previous stroke, or history of cardiovascular disease. We identified moderate correlations between fatigue and sleep disturbance (kappa = 0.72); memory and thinking impairment and reduced ADL (kappa = 0.68); and communication problems and ADL (kappa = 0.70).</div></div><div><h3>Interpretation</h3><div>Adverse non-motor outcomes are highly prevalent and often multiple at 6-months after stroke: 75% have at least one affected domain; fatigue, sleep disturbance, and reduced social participation each affect over 50% of survivors, and 26% of patients report ≥5 adverse outcomes. Our findings suggest an urgent need to better detect and mitigate these outcomes to improve quality of life after stroke.</div></div><div><h3>Funding</h3><div>The <span>National Institute for Health and Care Research</span> (NIHR) UCLH Biomedical Research Centre.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101080"},"PeriodicalIF":13.6,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poliovirus circulation in the WHO European region, 2015–2022: a review of data from WHO's three core poliovirus surveillance systems","authors":"Thea K. Fischer ,&nbsp;Caroline K. Johannesen ,&nbsp;Kimberley S.M. Benschop ,&nbsp;Natasa Berginc ,&nbsp;Eugene V. Saxentoff ,&nbsp;Shahin Huseynov ,&nbsp;José E. Hagan ,&nbsp;Heli Harvala","doi":"10.1016/j.lanepe.2024.101104","DOIUrl":"10.1016/j.lanepe.2024.101104","url":null,"abstract":"<div><h3>Background</h3><div>The Global Polio Eradication Initiative (GPEI) has drastically reduced the global incidence of poliomyelitis since its launch in 1988 thanks to effective vaccines and strong global surveillance systems. However, detections of wild-type as well as vaccine-derived poliovirus (VDPV) still occur, also in the WHO European Region. This study aims to describe the poliovirus detection via the acute flaccid paralysis (AFP), clinical enterovirus, and environmental surveillance systems.</div></div><div><h3>Methods</h3><div>In this study, we review data from annual reports from 2015 to 2022 from the World Health Organization (WHO)'s three core poliovirus surveillance systems in place in the WHO European Region: AFP, clinical enterovirus, and environmental surveillance systems.</div></div><div><h3>Findings</h3><div>A total of 4324 reported samples were found positive for poliovirus: 477 from AFP surveillance, 394 from clinical surveillance and 3453 from environmental surveillance. Of these, 366 were VDPV, 3952 vaccine strains, and 6 were wild-type poliovirus. 709 were identified as type 1, 399 as type 2, and 1944 type 3, while 1272 samples contained more than one type. Temporal and spatial association of positive environmental samples with positive samples from AFP or clinical enterovirus surveillance was found in only eight countries.</div></div><div><h3>Interpretation</h3><div>Analysis of poliovirus-positive samples from AFP, clinical enterovirus, and environmental surveillance revealed that type 3 poliovirus was the most prevalent type detected. Most poliovirus-positive samples were identified as vaccine strains. No information on sequences was available.</div></div><div><h3>Funding</h3><div>This study was funded by <span>WHO Regional Office for Europe</span> and received financial support from the <span>Bill and Melinda Gates Foundation</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101104"},"PeriodicalIF":13.6,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information provision and financial incentives in Catalonia's public primary care (2010–2019): an interrupted time series analysis","authors":"Roger Esteban-Fabró ,&nbsp;Ermengol Coma ,&nbsp;Eduardo Hermosilla ,&nbsp;Leonardo Méndez-Boo ,&nbsp;Carolina Guiriguet ,&nbsp;Gabriel Facchini ,&nbsp;Catia Nicodemo ,&nbsp;Josep Vidal-Alaball","doi":"10.1016/j.lanepe.2024.101102","DOIUrl":"10.1016/j.lanepe.2024.101102","url":null,"abstract":"<div><h3>Background</h3><div>The relative efficacy of information provision versus financial incentives in improving primary care quality remains a critical, unresolved question. We investigated these two strategies in Catalonia's public primary care system from 2010 to 2019: an innovative online platform providing real-time quality indicator information and targeted economic incentives for achieving indicator goals.</div></div><div><h3>Methods</h3><div>We conducted a comprehensive interrupted time series regression analysis on data from 272 primary care practices (5,628,080 patients). This analysis used linear regression models with Newey–West standard errors, and a sensitivity analysis including logit transformations to address ceiling effects. We evaluated 1) immediate post-intervention changes (step changes) in indicator results and inter-practice variability (coefficient of variation, CV), and 2) shifts in pre-intervention trends (slopes). We scrutinized 39 indicators after rigorous quality control: 23 novel (12 informed, 11 incentivized) and 16 derived from existing incentivized indicators. Robustness checks included 14 consistently incentivized and 10 non-intervened indicators. Overall, we assessed 63 indicators: 18 control, 13 follow-up, 9 quaternary prevention, 7 treatment, 7 diagnosis, 6 screening and 3 vaccination indicators.</div></div><div><h3>Findings</h3><div>Informed indicators showed positive impacts in 75% (9/12) of cases, and incentivized indicators in 64% (7/11) of cases. Incentivized indicators displayed improvements in annual trends ranging from 6.66 to 1.25 percentage points, with step changes up to 8.87 percentage points. Information led to step changes ranging from 19.67 to 1.07 percentage points, along with trend improvements between 1.09 and 0.34 percentage points annually. Both interventions were associated with step reductions in variability (up to −0.18 CV reduction) and significant trend improvements. Derived indicators showed limited improvements in results or variability (31%, 5/16), with minor step increases up to 2.22 percentage points.</div></div><div><h3>Interpretation</h3><div>Our findings reveal that information provision alone can match or even surpass the impact of financial incentives in improving care quality and reducing practice variability. This challenges conventional wisdom and offers a cost-effective, scalable approach to primary care quality enhancement, with far-reaching implications for global health policy.</div></div><div><h3>Funding</h3><div><span>European Union</span>, <span>Horizon Europe</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101102"},"PeriodicalIF":13.6,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11513846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence, prevalence and clinical presentation of inflammatory bowel diseases in Northern France: a 30-year population-based study","authors":"Hélène Sarter ,&nbsp;Thibaut Crétin ,&nbsp;Guillaume Savoye ,&nbsp;Mathurin Fumery ,&nbsp;Ariane Leroyer ,&nbsp;Luc Dauchet ,&nbsp;Thierry Paupard ,&nbsp;Hugues Coevoet ,&nbsp;Pauline Wils ,&nbsp;Nicolas Richard ,&nbsp;Dominique Turck ,&nbsp;Delphine Ley ,&nbsp;Corinne Gower-Rousseau","doi":"10.1016/j.lanepe.2024.101097","DOIUrl":"10.1016/j.lanepe.2024.101097","url":null,"abstract":"<div><h3>Background</h3><div>In industrialized countries, the incidence of inflammatory bowel disease (IBD) appears stabilized. This study examined the incidence and phenotype of IBD in Northern France over a 30-year period.</div></div><div><h3>Methods</h3><div>Including all IBD patients recorded in the EPIMAD population-based registry from 1988 to 2017 in Northern France, we described the incidence and clinical presentation of IBD according to age, sex and time.</div></div><div><h3>Findings</h3><div>A total of 22,879 incident IBD cases were documented (59% (n = 13,445) of Crohn’s disease (CD), 38% (n = 8803) of ulcerative colitis (UC), 3% (n = 631) of IBD unclassified (IBDU)). Over the study period, incidence of IBD, CD and UC was 12.7, 7.2 and 5.1 per 10⁵ person-years, respectively. The incidence of CD increased from 5.1/10⁵ in 1988–1990 to 7.9/10⁵ in 2015–2017 (annual percent change (APC): +1.9%, p &lt; 0.0001). The incidence of UC increased from 4.5/10⁵ to 6.1/10⁵ (APC: +1.3%, p &lt; 0.0001). The largest increase was observed in children (+4.3% in CD, p &lt; 0.0001; +5.4% in UC, p &lt; 0.0001) followed by young adults aged 17–39 years (+1.9% in CD, p &lt; 0.0001; +1.5% in UC, p &lt; 0.0001). The increase in UC incidence was significantly higher in women than in men (+1.9% in women, +0.8% in men; p = 0.006). We estimated that in our area, by 2030, nearly 0.6% of the population will have IBD.</div></div><div><h3>Interpretation</h3><div>The persistent increase of IBD incidence among children and young adults but also in women with UC in Northern France, suggests the persistence of substantial predisposing environmental factors.</div></div><div><h3>Funding</h3><div><span>Santé Publique France</span>; <span>INSERM</span>; <span>Amiens, Lille and Rouen University Hospitals</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101097"},"PeriodicalIF":13.6,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycoplasma pneumoniae incidence, phenotype, and severity in children and adolescents in Denmark before, during, and after the COVID-19 pandemic: a nationwide multicentre population-based cohort study","authors":"Kia H.S. Dungu ,&nbsp;Mette Holm ,&nbsp;Ulla Hartling ,&nbsp;Lise H. Jensen ,&nbsp;Allan Bybeck Nielsen ,&nbsp;Lisbeth S. Schmidt ,&nbsp;Lise B. Toustrup ,&nbsp;Lotte H. Hansen ,&nbsp;Kathrin W. Dahl ,&nbsp;Kirstine T. Matthesen ,&nbsp;Anne C. Nordholm ,&nbsp;Søren Uldum ,&nbsp;Hanne-Dorthe Emborg ,&nbsp;Maren J.H. Rytter ,&nbsp;Ulrikka Nygaard","doi":"10.1016/j.lanepe.2024.101103","DOIUrl":"10.1016/j.lanepe.2024.101103","url":null,"abstract":"<div><h3>Background</h3><div><em>Mycoplasma pneumoniae</em> infections resurged globally in 2023–2024 after a three-year decline during the COVID-19 pandemic. We explored the incidence and severity of <em>M pneumoniae</em> infections in children and adolescents before, during, and after the pandemic.</div></div><div><h3>Methods</h3><div>This nationwide, population-based cohort study included all Danish children and adolescents aged 0–17 years with a positive <em>M pneumoniae</em> PCR test from May 1, 2016, to April 30, 2024. We obtained clinical details for patients hospitalised for 24 h or more. Risk ratios for infections, hospitalisations, and disease manifestations in 2023–2024 versus pre-COVID-19 seasons were calculated using Fisher’s exact and Pearson’s χ² tests. A season was defined from May 1 to April 30.</div></div><div><h3>Findings</h3><div>Among the Danish population of 1,152,000 children and adolescents, 14,241 with a positive PCR test for <em>M pneumoniae</em> were included. In 2023–2024, children and adolescents with a positive PCR rose 2.9-fold (95% CI 2.8–3.1; p &lt; 0.0001) compared to the pre-COVID-19 seasons, and hospitalisations rose 2.6-fold (95% CI 2.0–3.3; p &lt; 0.0001). <em>M pneumoniae</em>-induced rash and mucositis increased 5.3-fold (95% CI 1.8–15.3; p = 0.0007). In 2023–2024 compared to the pre-COVID-19 seasons, there was no difference in the proportion of hospitalisation (360 [4%] of 8165 versus 230 [4%] of 6009; p = 0.09), the median duration of hospital stay (3 days [IQR 2–5] versus 3 days [IQR 2–5]; p = 0.84), or paediatric intensive care unit admission (14 [4%] of 360 versus 9 [4%] of 230 p = 1.00).</div></div><div><h3>Interpretation</h3><div>In Denmark, <em>M pneumoniae</em> infections and hospitalisations increased three-fold in 2023–2024 compared with the pre-COVID-19 seasons, indicating an immunity debt caused by the decline in <em>M pneumoniae</em> during the COVID-19 pandemic. While the severity of <em>M pneumoniae</em> infections did not change in 2023–2024, the five-fold increase in <em>M pneumoniae</em>-induced rash and mucositis in children and adolescents highlights <em>M pneumoniae</em> as an important pathogen causing mucocutaneous eruptions.</div></div><div><h3>Funding</h3><div><span>Innovation Fund Denmark</span> and <span>Rigshospitalets Forskningsfond</span>.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101103"},"PeriodicalIF":13.6,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142446960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical and cognitive stressors exacerbate symptoms in long COVID: more evidence triggering new research and therapeutic needs","authors":"Danilo Buonsenso ,&nbsp;Lael M. Yonker","doi":"10.1016/j.lanepe.2024.101109","DOIUrl":"10.1016/j.lanepe.2024.101109","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"46 ","pages":"Article 101109"},"PeriodicalIF":13.6,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142444653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are all ultra-processed foods bad for health? – Author's reply","authors":"Samuel J. Dicken","doi":"10.1016/j.lanepe.2024.101108","DOIUrl":"10.1016/j.lanepe.2024.101108","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"46 ","pages":"Article 101108"},"PeriodicalIF":13.6,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142444654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Axillary lymph node dissection in breast cancer patients: obsolete or still necessary?","authors":"Gianluca Vanni ,&nbsp;Marco Pellicciaro ,&nbsp;Oreste Claudio Buonomo","doi":"10.1016/j.lanepe.2024.101107","DOIUrl":"10.1016/j.lanepe.2024.101107","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"47 ","pages":"Article 101107"},"PeriodicalIF":13.6,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142446959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are all ultra-processed foods bad for health?","authors":"Carlos Augusto Monteiro ,&nbsp;Leandro F.M. Rezende","doi":"10.1016/j.lanepe.2024.101106","DOIUrl":"10.1016/j.lanepe.2024.101106","url":null,"abstract":"","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"46 ","pages":"Article 101106"},"PeriodicalIF":13.6,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142444865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}