eJournal of Oral Maxillofacial Research最新文献

Background: Aplasia of the salivary glands, either partial or involving all the major and possibly the minor salivary glands, is a very rare cause of hyposalivation. The aim of this case report is to present a case of aplasia of the major and minor salivary glands and discuss the relevant literature.

Methods: A 23-year-old woman, with a non-contributory medical and family history was referred due to rampant caries, that could not be attributed to any obvious aetiology. No sicca symptoms, previous parotid gland swelling or general symptoms were reported. Clinically, oral mucosa dryness and extended dental erosions and caries were observed, while the orifices of the excretory ducts of the parotid and submandibular salivary glands were not evident. Unstimulated and stimulated saliva flow rates were severely diminished, while a diagnostic biopsy of the lower lip revealed absence of minor salivary glands. Detailed hematologic and immunological investigations to exclude systemic disorders were also within normal limits. Ultrasound and magnetic resonance imaging revealed the absence of all major salivary glands, confirming the clinical diagnosis of congenital aplasia of the salivary glands.

Results: Oral hygiene instructions and dietary advice were given while dental products with fluoride and saliva substitutes were administered and appropriate dental treatment was implemented. Regular dental follow-up was also advised.

Conclusions: Timely diagnosis of aplasia of the salivary glands is important, considering the detrimental effects of the absence of saliva on oral health. Management consists of the use of saliva substitutes, nutritional adaptation, maintenance of oral health and regular dental follow-ups.

Objectives: The purpose of this experimental study was to investigate the correlation between the frictional resistance torque of tap drilling prior to implant placement and the primary stability after implant placement.

Material and methods: Solid rigid polyurethane bone blocks of four different densities were used in this study. A computerized surgical implant motor device was utilized to measure the frictional resistance torque of tap drilling. After the tap torque was measured, the dental implants were inserted at the prepared sites. During the implantation, the insertion torque was recorded, and resonance frequency analysis was performed, the value of which was calculated as the implant stability quotient. Thereafter, the correlation between the tap torque and the primary stability of the implant was evaluated and compared with the standard drilling protocol.

Results: A significant positive correlation was found between the tap torque and insertion torque (Pearson's r = 0.88, P < 0.0001). Similarly, there was a positive correlation between the tap torque and implant stability quotient (Pearson's r = 0.69, P < 0.0001).

Conclusions: These results suggest that measurement of the frictional resistance torque of tap drilling prior to implant placement could provide helpful information for implant primary stability.

Objectives: This pilot study evaluated the relationship between inferior alveolar nerve location through computed tomography scan and intraoperative inferior alveolar nerve entrapment after bilateral sagittal split osteotomy.

Material and methods: Overall, 20 helicoidal computed tomography scans were evaluated in patients with facial deformities who underwent to bilateral sagittal split osteotomy (BSSO). The distance from the mandibular canal to the internal surface of the buccal and lingual cortical bone, mandibular thickness, bone density and proportion of medullary and cortical bone in 3 regions were evaluated. During the intraoperative period, the segment to which the nerve remained adhered after performing BSSO was analysed, and the data correlated.

Results: The distance from the mandibular canal to the buccal cortical bone showed a mean of 2.6 mm when the inferior alveolar nerve was adhered to the distal segment and mean of 0.7 mm when the nerve was adhered to the proximal segment. The thickness was 11.2 mm and 9.8 mm when the nerve was adhered the distal the proximal segments respectively. Mandibular thickness, distance from the mandibular canal to the buccal and lingual cortical were statistically related to intraoperative nerve entrapment (P < 0.05).

Conclusions: Narrow jaws and the distance from the mandibular canal to buccal cortical bone less than 2 mm increases the risk of the inferior alveolar nerve entrapment in bilateral sagittal split osteotomy.

Background: Epidermoid cysts are benign lesions that occur throughout the body. Their development in the oral cavity is extremely rare. Intraosseous epidermoid cysts of the jaw are even rarer and difficult to distinguish from other lesions. For this reason, we would like to draw the attention of practitioners to this pathology as a differential diagnosis through the presented clinical case.

Methods: This study presents an unusual case of a type of epidermoid cyst in an edentulous maxilla. A 70-year-old man was referred to the Maxillofacial Surgery Division at the University Multiprofile Hospital for Active Treatment and Emergency Medicine "N. I. Pirogov", Sofia, Bulgaria, for a single radiolucent area in his anterior maxilla. The patient underwent surgery to extract the cyst.

Results: Based on the clinical and radiographic evaluation, a preliminary diagnosis of dentigerous residual cyst was made. The histopathological examination of the hematoxylin and eosin stained sections revealed an epidermoid cyst based on the observed thick keratin layer resembling epidermis together with the stratified squamous epithelium lining with many layers of sheaves of orthokeratin.

Conclusions: This report presents an uncommon case of an intraosseous epidermoid cyst occurring without a history of maxillary trauma. Although intraosseous epidermoid cysts are extremely rare in jaws, they should be considered in the differential diagnosis of radiolucent lesions.

Objectives: The presented case-control study was developed to characterize the clinical, histopathological and immunological profile of patients with traumatic injuries, benign neoplasms, potentially malignant oral disorders and malignant neoplasms of the oral cavity, in order to identify biomarkers of malignancy.

Material and methods: Clinical information was collected from dental records and several techniques were performed, including histopathological evaluation in sections stained with haematoxylin and eosin, immunohistochemistry for programmed death ligand-1 and measurement of serum levels of interferon-gamma, interleukin-6, -10 and -12. Statistical analysis was performed using IBM SPSS^® Statistics software.

Results: This study included 8 patients with traumatic injuries, 8 with benign neoplasms, 6 with potentially malignant oral disorders and 11 with malignant neoplasms. An association was observed between the classification of the lesion and smoking (P < 0.05), the size of the lesion (P < 0.05), the density of the inflammatory infiltrate (P < 0.001), the degree of dysplasia (P < 0.01) and programmed death ligand-1 expression (P < 0.01).

Conclusions: Therefore, it is suggested that smoking, the size of the lesion, the inflammatory infiltrate and the programmed death ligand-1 expression can be considered potential biomarkers of oral malignancy.

Objectives: The aim of this retrospective study was to investigate anatomical structure of mandibular canal and the factors those increase the possibility of inferior alveolar nerve damage in mandibular third molar region of Turkish population.

Material and methods: Overall 320 participants with 436 mandibular third molars were included from four different study centers. Following variables were measured: type and depth of third molar impaction, position of mandibular canal in relation to third molars, morphology of mandibular canal, cortication status of mandibular canal, possible contact between the third molars and mandibular canal, thickness and density of superior, buccal, and lingual mandibular canal wall, bucco-lingual and apico-coronal mandibular canal diameters on cone-beam computed tomography scans.

Results: Lingual mandibular canal wall density and thickness were decreased significantly as the impaction depth of mandibular third molar was increased (P = 0.045, P = 0.001 respectively). Highest buccal mandibular canal wall density and thickness were observed in lingual position of mandibular canal in relation to mandibular third molar (P = 0.021, P = 0.034 respectively). Mandibular canal with oval/round morphology had higher apico-coronal diameter in comparison to tear drop and dumbbell morphologies (P = 0.018). Additionally, mandibular canals with observed cortication border and no contact with mandibular third molar had denser and thicker lingual mandibular canal wall (P = 0.003, P = 0.001 respectively).

Conclusions: Buccal and lingual mandibular canal wall density, thickness and mandibular canal diameter may be related with high-risk indicators of inferior alveolar nerve injury.

Background: Focal osteoporotic bone marrow defect is asymptomatic radiolucent area usually discovered incidentally during radiographic examination of the jaws. This bone condition can lead to clinical complications during dental implant placement or during osseointegration process.

Methods: A 54-year-old woman was referred to private dental implant centre for a dental implant rehabilitation treatment in May 17, 2016. Oral examination revealed a healthy mucosa with no visible pathology. Adentia of tooth #46 and moderate atrophy of the edentulous alveolar process were found. Panoramic radiography of the jaws showed 2 cm x 2 cm radiolucency with irregular borders located in tooth #46 region. The margins of the bone defect were uneven, single trabeculae were visible, and the cortical layer was not deformed. In the absence of signs of pathology, it was decided to perform a dental implant surgery in the edentulous jaw segment #46.

Results: The osteoporotic focus was filled with natural bovine bone substitute Cerabone^®. The granules were gently condensed to the sides - to the buccal and lingual walls until they filled the entire cavity. A 10 mm long, 4.1 mm diameter Straumann^® Tissue Level implant was surgically placed with the shoulder of the implant resting on the margins of the osteotomy. It was proposed six steps protocol for surgical dental implant installation in focal osteoporotic bone marrow defect in mandible.

Conclusions: A six-step protocol for surgical placement of dental implants in focal osteoporotic bone marrow defects may be a useful tool for clinicians in implant dentistry.

Objectives: The objectives of this clinical observational study are to measure peri-implant crevicular fluid volume based on dental implant diameter and length, and to evaluate the possible relationship between peri-implant crevicular fluid/gingival crevicular fluid volumes and clinical periodontal indices.

Material and methods: The information about length and diameter of dental implants was noted. Clinical indices (probing depth, plaque index, gingival bleeding time index, and gingival index) were recorded. Peri-implant crevicular fluid (PICF)/gingival crevicular fluid (GCF) volumes were measured from 4 sites (mesial, buccal, distal, and lingual/palatal) of each dental implant including its one or more equivalent natural tooth/teeth.

Results: One-hundred-sixty-one loaded dental implants and 221 natural teeth of 101 patients were evaluated. The length of dental implant had no effect on PICF volume (P > 0.05). However, PICF volumes of narrow (< 3.5 mm) and wide (> 4.5 mm) diameter implants were higher than standard diameter implants (≥ 3.5 mm, and ≤ 4.5 mm) (P < 0.05). PICF and GCF volumes of areas with peri-implant/periodontal diseases were significantly higher than healthy areas (P < 0.05). PICF and GCF volumes showed positive correlations with clinical indices (P < 0.05).

Conclusions: In accordance with the results of the present study, the implant diameter, not the implant length, affects peri-implant crevicular fluid volume.

Objectives: The aim of the present systematic review was to evaluate the dimensional influence of the epithelialized tissue graft harvested from the palate in the postoperative pain.

Material and methods: Research was conducted in electronic databases Cochrane Library, Embase, LILACS, PubMed, Scopus, and Web of Science upwards May 15, 2022. Studies that reported the influence of graft dimensions of palatal epithelized harvesting on postoperative pain were eligible. The evaluation was made using the methodological quality assessment by Joanna Briggs Institute Critical Appraisal Checklist for randomized clinical trials and non-randomized studies and the level of evidence according to GRADE.

Results: Four studies were included. The clinical and methodological heterogeneity among studies led to an analysed narrative. The postoperative pain was assessed during the period of 1 to 28 postoperative days. It was determined by using visual analog scale in three studies, while the evaluation was performed indirectly based on analgesics intake in one study. According to three studies, bigger graft sizes were associated with higher postoperative pain. The methodological quality assessment categorized two study as high (one randomized control trial and one non-randomized), and two as moderate (one randomized control trial and one non-randomized). The data was considered moderate.

Conclusions: Based on the moderate certainty level, bigger graft sizes of palatal epithelized harvesting appear to promote more postoperative pain. Understanding the postoperative pain as a response to a graft extension may assist some clinical decisions regarding the surgical periodontal and peri-implant planning.

Objectives: The aim of this cross-sectional study was to examine the method error and reliability of acoustic pharyngometry and rhinometry in children and adolescents and to describe the feasibility of these methods in a young population.

Material and methods: The study sample included 35 healthy subjects in the age of 9 to 14 years. The subjects were randomly recruited for the present project in the period from June 2021 to February 2022. Repeated measurements of the upper airway dimensions in standing mirror position were performed by the use of Acoustic Pharyngometer and Rhinometer. Volume (cm³), calculated resistance (cm H₂O/L/min), mean area (cm²), minimum cross-sectional area (MCA, cm²) and distance to MCA (cm) were examined. Method errors and reliability coefficients were evaluated using Dahlberg's formula and the Houston reliability coefficient. The feasibility of the methods were analysed using paired t-test and estimated by difference in drop-out rates.

Results: No systematic error exhibited in the repeated measurements except volume in the left nostril (P = 0.017). The method errors of the acoustic pharyngometry and rhinometry were betweeen 0.0002 to 0.069 and 0.001 to 0.082 respectively. The Houston reliability coefficient for both methods were between 0.952 to 0.999. The acoustic pharyngometry was significantly more feasible compared to rhinometry (P < 0.001).

Conclusions: The study shows that acoustic pharyngometry and rhinometry in the standing mirror position are reliable methods, with acoustic pharyngometry being even more feasible than rhinometry, which is why it is recommended to practice the methods with children and ensure reliability of results before registering measurements.