{"title":"Severe abdominal aortic and iliac arteriosclerosis","authors":"Y. Kajihara","doi":"10.29333/jcei/13197","DOIUrl":"https://doi.org/10.29333/jcei/13197","url":null,"abstract":"<jats:p xml:lang=\"en\">N/A</jats:p>","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41654799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Nowadays, fructose is recognized as a significant health threat. Prepared foods containing fructose are consumed more because they do not create a feeling of satiety. Selenium is an essential trace element with antioxidant and cell protective properties. In this study, the effect of high fructose corn syrup, which is used as a sweetener in many foods and beverages and consumed during pregnancy, and the possible protective role of selenium in this effect were investigated and examined. Methods: Fertilized specific pathogen-free eggs were used in our study. These eggs were divided equally into four groups. Each group was allocated 10 eggs containing viable embryos. These groups are pre-process control, post-process control, high fructose corn syrup (HFCS-55), and high fructose corn syrup and selenium (HFCS-55+Se 10-6) groups. Pellets containing and containing no active substance (HFCS-55, HFCS-55+Se 10-6) were carefully placed on the chorioallantoic membrane (CAM) of each egg in these groups. Oxidative stress status in all groups was determined by total oxidative stress (TOS) and total antioxidant capacity (TAC) methods. Results: In our study, a significant increase in TOS levels and a significant decrease in TAC levels were observed in egg groups given HFCS compared to other groups (p<0.05). The OSI value was shown to be lower in the group given HFCS+Se. Conclusion: As a result, HFCS was shown to increase oxidative stress. In line with our data, it has been shown that Se, plays a protective role against oxidative stress.
{"title":"The protective role of selenium in an experimental high fructose corn syrup exposure","authors":"Ozlem Sanli Esme, H. Savaş, M. Sozen, Elina Dinc","doi":"10.29333/jcei/12998","DOIUrl":"https://doi.org/10.29333/jcei/12998","url":null,"abstract":"Objective: Nowadays, fructose is recognized as a significant health threat. Prepared foods containing fructose are consumed more because they do not create a feeling of satiety. Selenium is an essential trace element with antioxidant and cell protective properties. In this study, the effect of high fructose corn syrup, which is used as a sweetener in many foods and beverages and consumed during pregnancy, and the possible protective role of selenium in this effect were investigated and examined.\u0000Methods: Fertilized specific pathogen-free eggs were used in our study. These eggs were divided equally into four groups. Each group was allocated 10 eggs containing viable embryos. These groups are pre-process control, post-process control, high fructose corn syrup (HFCS-55), and high fructose corn syrup and selenium (HFCS-55+Se 10-6) groups. Pellets containing and containing no active substance (HFCS-55, HFCS-55+Se 10-6) were carefully placed on the chorioallantoic membrane (CAM) of each egg in these groups. Oxidative stress status in all groups was determined by total oxidative stress (TOS) and total antioxidant capacity (TAC) methods.\u0000Results: In our study, a significant increase in TOS levels and a significant decrease in TAC levels were observed in egg groups given HFCS compared to other groups (p<0.05). The OSI value was shown to be lower in the group given HFCS+Se.\u0000Conclusion: As a result, HFCS was shown to increase oxidative stress. In line with our data, it has been shown that Se, plays a protective role against oxidative stress.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41353174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.20944/preprints202211.0153.v1
M. Ohe, H. Shida, Junya Yamamoto, Masahide Seki, K. Furuya
N/A
不适用
{"title":"Successful treatment with minocycline and Saiko-keishi-to for COVID-19","authors":"M. Ohe, H. Shida, Junya Yamamoto, Masahide Seki, K. Furuya","doi":"10.20944/preprints202211.0153.v1","DOIUrl":"https://doi.org/10.20944/preprints202211.0153.v1","url":null,"abstract":"<jats:p xml:lang=\"en\">N/A</jats:p>","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48457631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advanced gastric cancer in a young-age patient","authors":"Y. Kajihara","doi":"10.29333/jcei/12997","DOIUrl":"https://doi.org/10.29333/jcei/12997","url":null,"abstract":"<jats:p xml:lang=\"en\">N/A</jats:p>","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45579377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masashi Ohe, Haruki Shida, Junya Yamamoto, Masahide Seki, Ken Furuya
{"title":"Successful treatment with minocycline and Saiko-keishi-to for COVID-19","authors":"Masashi Ohe, Haruki Shida, Junya Yamamoto, Masahide Seki, Ken Furuya","doi":"10.29333/jcei/12999","DOIUrl":"https://doi.org/10.29333/jcei/12999","url":null,"abstract":"","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135017189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An elderly man with a malpositioned Foley catheter","authors":"Y. Kajihara","doi":"10.29333/jcei/12543","DOIUrl":"https://doi.org/10.29333/jcei/12543","url":null,"abstract":"<jats:p xml:lang=\"en\">N/A</jats:p>","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44931626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: A wide variety of diseases lead to pericardial effusion including systemic inflammatory diseases, pericarditis, reduced pericardial fluid reabsorption due to increased systemic venous pressure, pneumonia, pulmonary embolism, endocrine diseases, post-cardiotomy syndrome, trauma, hypothyroidism, renal-hepatic failure, collagen-vascular diseases, infectious, and malignancy. In this study, we aimed to evaluate the underlying etiology of pericardial effusions in patients underwent surgical pericardial drainage or pericardial window and contemporary management. Materials and methods: Between January 2006 and January 2018, a total of 81 patients (49 males, 32 females; mean 52.9±10.6 years; range 5 to 84 years) who underwent subxiphoid pericardiostomy, pericardial window procedure with left anterior thoracotomy or subxiphoid approach, due to moderate or severe pericardial effusion and cardiac tamponade, were retrospectively analyzed. Results: Malignancy was diagnosed either with histopathological examination of the pericardial biopsy and/or fluid in 17 (80.9%) of 21 patients had a previous history of malignancy. Of the 21 patients diagnosed with malignancy, six patients (7.5%) had leukemia/lymphoma, and six patients (7.5%) had thyroid papillary cancer. Mycobacterium tuberculosis was identified in only one (1.2%) patient’s culture of the pericardial fluid. No etiology was found in the remaining 38 patients (46.9%); thus, they were considered as idiopathic pericarditis. Conclusion: Tuberculosis is no longer the leading cause of pericarditis. Idiopathic pericarditis is the leading cause of pericardial effusion and malignancy is the next most common cause of pericardial effusion in our region.
{"title":"Evaluation of etiology of pericardial effusion in 81 patients who underwent pericardiostomy or pericardial window","authors":"S. B. Deşer, B. Arapi","doi":"10.29333/jcei/12605","DOIUrl":"https://doi.org/10.29333/jcei/12605","url":null,"abstract":"Introduction: A wide variety of diseases lead to pericardial effusion including systemic inflammatory diseases, pericarditis, reduced pericardial fluid reabsorption due to increased systemic venous pressure, pneumonia, pulmonary embolism, endocrine diseases, post-cardiotomy syndrome, trauma, hypothyroidism, renal-hepatic failure, collagen-vascular diseases, infectious, and malignancy. In this study, we aimed to evaluate the underlying etiology of pericardial effusions in patients underwent surgical pericardial drainage or pericardial window and contemporary management.\u0000Materials and methods: Between January 2006 and January 2018, a total of 81 patients (49 males, 32 females; mean 52.9±10.6 years; range 5 to 84 years) who underwent subxiphoid pericardiostomy, pericardial window procedure with left anterior thoracotomy or subxiphoid approach, due to moderate or severe pericardial effusion and cardiac tamponade, were retrospectively analyzed.\u0000Results: Malignancy was diagnosed either with histopathological examination of the pericardial biopsy and/or fluid in 17 (80.9%) of 21 patients had a previous history of malignancy. Of the 21 patients diagnosed with malignancy, six patients (7.5%) had leukemia/lymphoma, and six patients (7.5%) had thyroid papillary cancer. Mycobacterium tuberculosis was identified in only one (1.2%) patient’s culture of the pericardial fluid. No etiology was found in the remaining 38 patients (46.9%); thus, they were considered as idiopathic pericarditis.\u0000Conclusion: Tuberculosis is no longer the leading cause of pericarditis. Idiopathic pericarditis is the leading cause of pericardial effusion and malignancy is the next most common cause of pericardial effusion in our region.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44433947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Inci, K. Ulusan, Gulsen Yoruk, Nagehan Didem Sarı
{"title":"Evaluation of colonoscopy results in HIV infected cases","authors":"A. Inci, K. Ulusan, Gulsen Yoruk, Nagehan Didem Sarı","doi":"10.29333/jcei/12419","DOIUrl":"https://doi.org/10.29333/jcei/12419","url":null,"abstract":"","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44380680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Partial leukonychia","authors":"Y. Kajihara","doi":"10.29333/jcei/12409","DOIUrl":"https://doi.org/10.29333/jcei/12409","url":null,"abstract":"","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42530042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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