Pub Date : 2020-12-28DOI: 10.24125/sanamed.v15i3.431
H. Ozsoy, Lamia Najafova, Huseyin Kurtulmus
Background: Temporomandibular disorders (TMD) is a term covering heterogeneous musculoskeletal disorders, including the temporomandibular joint and related structures. Pain is a common symptom in TMD. Chronic pain is a condition that affects the physical, psychological, cognitive and social domains of people who frequently have negative effects on quality of life. Illness cognitions is defined that patients who have a chronic illness have their own beliefs about their illness. In another saying, illness cognitions contain patient’s perception and understanding of the disease and its treatment. Material and Methods: This study was performed on 80 patients who applied to clinic with chronic TMD disorder. A written consent was obtained from the appropriate participants and the Illness Cognition Questionnaire (ICQ) forms were filled in by the patients under the guidance of the researchers. The statistical software SPSS (Statistical Package for Social Sciences, Version 20, Chicago IL, USA) was used. Results: ICQ subscores of individuals with TMD: The mean score was 16.95 (SD = 4.05) for helplessness, 10.36 (SD = 3.14) for acceptance, and 15.55 (SD = 3.70) for perceived benefits. There was a statistically significant intra class correlation of 93.8% (0.915-0.957) among the Acceptance and 92.5% (0.896-0.948) among the Perceived benefits scale scores of the participants. Conclusion: Psychological interventions that can create a positive perception against TMD and highlight the ability to overcome problem-oriented TMD, can prevent the disease from controlling the daily life of people with TMD in a positive way and can help to affect the health promotion process positively.
{"title":"ILLNESS COGNITIONS IN PATIENTS WITH TEMPOROMANDIBULAR DISORDERS","authors":"H. Ozsoy, Lamia Najafova, Huseyin Kurtulmus","doi":"10.24125/sanamed.v15i3.431","DOIUrl":"https://doi.org/10.24125/sanamed.v15i3.431","url":null,"abstract":"Background: Temporomandibular disorders (TMD) is a term covering heterogeneous musculoskeletal disorders, including the temporomandibular joint and related structures. Pain is a common symptom in TMD. Chronic pain is a condition that affects the physical, psychological, cognitive and social domains of people who frequently have negative effects on quality of life. Illness cognitions is defined that patients who have a chronic illness have their own beliefs about their illness. In another saying, illness cognitions contain patient’s perception and understanding of the disease and its treatment. Material and Methods: This study was performed on 80 patients who applied to clinic with chronic TMD disorder. A written consent was obtained from the appropriate participants and the Illness Cognition Questionnaire (ICQ) forms were filled in by the patients under the guidance of the researchers. The statistical software SPSS (Statistical Package for Social Sciences, Version 20, Chicago IL, USA) was used. Results: ICQ subscores of individuals with TMD: The mean score was 16.95 (SD = 4.05) for helplessness, 10.36 (SD = 3.14) for acceptance, and 15.55 (SD = 3.70) for perceived benefits. There was a statistically significant intra class correlation of 93.8% (0.915-0.957) among the Acceptance and 92.5% (0.896-0.948) among the Perceived benefits scale scores of the participants. Conclusion: Psychological interventions that can create a positive perception against TMD and highlight the ability to overcome problem-oriented TMD, can prevent the disease from controlling the daily life of people with TMD in a positive way and can help to affect the health promotion process positively.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44356852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-28DOI: 10.24125/sanamed.v15i3.453
B. Uğuz, S. Tiryakioğlu, E. Dal, Aysu Tihan, K. Yalın, H. Ozkan
Objective: The usage of synthetic cannabinoids (SCs) has increased both in Turkey and all worldwide. Here, we evaluate if SCs cause ventricular repolarization abnormalities using initial and after 12 th- hour electrocardiograms in patients with acute intoxication of SCs. We examined changes in the QTc and cTp-e parameters to demonstrate ventricular repolarization effects of the usage of SCs. Material and Methods: We used a prospective study design. Twenty patients were included who visited the emergency department, complaining of clouding of consciousness after using SCs. The QT, QTc and Tp-e intervals and several other electrocardiographic parameters were measured at baseline and 12 hours after the usage of SCs. Results: The QRS duration was significantly decreased (102.1±15.5 ms vs 95.0±10.7 ms; p=0.022). We noted a significant decrease in cQT measurements at the end of the 12 th hour (426.6±47.2 ms vs 390.4±42.9 ms; p=0.002). Similarly, the Tp-e and cTp-e values decreased significantly when SCs lost its acute effect (93.4±21.1 ms vs 77.4±21.0 ms; p=0.014, 105.3±28.5 ms vs 88.1±21.5 ms; p=0.01). Conclusions: The usage of SCs affects ventricular repolarization heterogeneity based on QTc and Tp-e intervals.
目的:合成大麻素(SCs)的使用在土耳其和世界各地都有所增加。在这里，我们使用急性sc中毒患者的初始和12小时后的心电图来评估sc是否引起心室复极异常。我们检测了QTc和cTp-e参数的变化，以证明使用SCs对心室复极的影响。材料和方法:我们采用前瞻性研究设计。20例患者就诊于急诊科，主诉使用SCs后意识模糊。在基线和使用SCs后12小时测量QT间期、QTc和Tp-e间期及其他几个心电图参数。结果:QRS持续时间明显缩短(102.1±15.5 ms vs 95.0±10.7 ms;p = 0.022)。我们注意到在第12小时结束时cQT测量值显著下降(426.6±47.2 ms vs 390.4±42.9 ms;p = 0.002)。同样，当sc失去急性效应时，Tp-e和cTp-e值显著下降(93.4±21.1 ms vs 77.4±21.0 ms;P =0.014, 105.3±28.5 ms vs 88.1±21.5 ms;p = 0.01)。结论:基于QTc和Tp-e间期，SCs的使用影响心室复极化异质性。
{"title":"ACUTE EFFECTS OF SYNTHETIC CANNABINOIDS ON VENTRICULAR REPOLARIZATION","authors":"B. Uğuz, S. Tiryakioğlu, E. Dal, Aysu Tihan, K. Yalın, H. Ozkan","doi":"10.24125/sanamed.v15i3.453","DOIUrl":"https://doi.org/10.24125/sanamed.v15i3.453","url":null,"abstract":"Objective: The usage of synthetic cannabinoids (SCs) has increased both in Turkey and all worldwide. Here, we evaluate if SCs cause ventricular repolarization abnormalities using initial and after 12 th- hour electrocardiograms in patients with acute intoxication of SCs. We examined changes in the QTc and cTp-e parameters to demonstrate ventricular repolarization effects of the usage of SCs. Material and Methods: We used a prospective study design. Twenty patients were included who visited the emergency department, complaining of clouding of consciousness after using SCs. The QT, QTc and Tp-e intervals and several other electrocardiographic parameters were measured at baseline and 12 hours after the usage of SCs. Results: The QRS duration was significantly decreased (102.1±15.5 ms vs 95.0±10.7 ms; p=0.022). We noted a significant decrease in cQT measurements at the end of the 12 th hour (426.6±47.2 ms vs 390.4±42.9 ms; p=0.002). Similarly, the Tp-e and cTp-e values decreased significantly when SCs lost its acute effect (93.4±21.1 ms vs 77.4±21.0 ms; p=0.014, 105.3±28.5 ms vs 88.1±21.5 ms; p=0.01). Conclusions: The usage of SCs affects ventricular repolarization heterogeneity based on QTc and Tp-e intervals.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44728266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-28DOI: 10.24125/sanamed.v15i3.456
C. Haki, O. Akdogan, İ. Bora
Objective: In this study, we aim to share the data of patients who were followed-up and treated with a diagnosis of juvenile myoclonic epilepsy (JME), and to draw attention to the difficulties in diagnosis and the problems that may occur in treatment. Method: In this study, seizure types, demographic and EEG characteristics of 75 patients with JME were retrospectively analyzed in our tertiary care center. Results: Of the total 75 cases, 48 patients (64%) were female and 27 patients (36%) were male. The overall female/male ratio was 1.7/1. The age of onset of seizures ranged from 6 to 24 years old. According to seizure types, all patients had myoclonic seizures, 65 patients (86%) had generalized tonic clonic seizures and 17 patients (22.6%) had absence seizures. Of the cases, 13 patients (17.3%) had febrile convulsions, 4 patients (5.3%) had a history of febrile convulsions in their families and 10 patients (13.3%) had a family history of epilepsy. For 63 (84%) patients, seizures were under control with valproic acid alone. When the patients EEGs were examined, 55 patients (73.3%) had generalized epileptiform activity, 11 patients (14.7%) had focal abnormaly and 9 patients (12%) had no abnormality. It was determined that the diagnosis of JME was not established at the onset of the disease and the seizures were not under control for 40% of the patients who were admitted to our outpatient clinic from different centers. Conclusion: Physicians should be very careful in the diagnosis of JME and the presence of myoclonia and absence seizures should be questioned in all patients presenting with generalized tonic-clonic seizures between 8-20 years of age in polyclinic practice.
{"title":"DIAGNOSTIC DIFFICULTIES IN PATIENTS WITH JUVENILE MYOCLONIC EPILEPSY","authors":"C. Haki, O. Akdogan, İ. Bora","doi":"10.24125/sanamed.v15i3.456","DOIUrl":"https://doi.org/10.24125/sanamed.v15i3.456","url":null,"abstract":"Objective: In this study, we aim to share the data of patients who were followed-up and treated with a diagnosis of juvenile myoclonic epilepsy (JME), and to draw attention to the difficulties in diagnosis and the problems that may occur in treatment. Method: In this study, seizure types, demographic and EEG characteristics of 75 patients with JME were retrospectively analyzed in our tertiary care center. Results: Of the total 75 cases, 48 patients (64%) were female and 27 patients (36%) were male. The overall female/male ratio was 1.7/1. The age of onset of seizures ranged from 6 to 24 years old. According to seizure types, all patients had myoclonic seizures, 65 patients (86%) had generalized tonic clonic seizures and 17 patients (22.6%) had absence seizures. Of the cases, 13 patients (17.3%) had febrile convulsions, 4 patients (5.3%) had a history of febrile convulsions in their families and 10 patients (13.3%) had a family history of epilepsy. For 63 (84%) patients, seizures were under control with valproic acid alone. When the patients EEGs were examined, 55 patients (73.3%) had generalized epileptiform activity, 11 patients (14.7%) had focal abnormaly and 9 patients (12%) had no abnormality. It was determined that the diagnosis of JME was not established at the onset of the disease and the seizures were not under control for 40% of the patients who were admitted to our outpatient clinic from different centers. Conclusion: Physicians should be very careful in the diagnosis of JME and the presence of myoclonia and absence seizures should be questioned in all patients presenting with generalized tonic-clonic seizures between 8-20 years of age in polyclinic practice.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43472585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-28DOI: 10.24125/sanamed.v15i3.448
M. Ranisavljevic, Ljiljana Budisic Ranisavljevic, V. Selaković, D. Lukić
Introduction: Secondary breast reconstruction is a multifactorial decision. It is based on the need for neoadjuvant/adjuvant treatment, lifestyle and expected cosmetic outcome of the patient. Aim of this study was to show early complications related with secondary breast reconstruction using latissimus dorsi miocutaneous flap and silicone breast implants. Material and methods: This retrospective study was made with 24 patients who were treated at the Institute for Oncology Vojvodina in the period from 2007 to 2013. At all patients we underwent secondary breast reconstruction using pedicle latissimus dorsi myocutaneous flap (LDMF) and silicone breast implant. Results: Almost at all patients we identified prolonged seroma formation like complication related to donor site (21/24 (87.5%)). Radiotherapy and chemiotherapy after first operation have statistical significance on complications after LDMF. Smoking and obesity have no influence on complications Conclusion: Breast reconstruction using LDMF is related with small number of early postoperative complications and gives acceptable aesthetic results.
{"title":"EARLY COMPLICATIONS AFTER SECONDARY BREAST RECONSTRUCTION USING LATISSIMUS DORSI MYOCUTANEOUS FLAP AND SILICONE BREAST IMPLANTS","authors":"M. Ranisavljevic, Ljiljana Budisic Ranisavljevic, V. Selaković, D. Lukić","doi":"10.24125/sanamed.v15i3.448","DOIUrl":"https://doi.org/10.24125/sanamed.v15i3.448","url":null,"abstract":"Introduction: Secondary breast reconstruction is a multifactorial decision. It is based on the need for neoadjuvant/adjuvant treatment, lifestyle and expected cosmetic outcome of the patient. Aim of this study was to show early complications related with secondary breast reconstruction using latissimus dorsi miocutaneous flap and silicone breast implants. Material and methods: This retrospective study was made with 24 patients who were treated at the Institute for Oncology Vojvodina in the period from 2007 to 2013. At all patients we underwent secondary breast reconstruction using pedicle latissimus dorsi myocutaneous flap (LDMF) and silicone breast implant. Results: Almost at all patients we identified prolonged seroma formation like complication related to donor site (21/24 (87.5%)). Radiotherapy and chemiotherapy after first operation have statistical significance on complications after LDMF. Smoking and obesity have no influence on complications Conclusion: Breast reconstruction using LDMF is related with small number of early postoperative complications and gives acceptable aesthetic results.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42230035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-28DOI: 10.24125/sanamed.v15i3.452
Neslihan Eskut, Pınar Tamer, D. Delibaş, Esin Erdoğan
Introduction: The aim of this study is to investigate the relationship between clinical features, sleep quality, fatigue and mental symptoms in epileptic patients. Material and Methods: This cross-sectional study was conducted at epilepsy outpatient clinic of Bozyaka Training and Research Hospital. 81 patients who were followed up for the diagnosis of epilepsy were included in the study. The patients were administered a sociodemographic data form, Pittsburgh Sleep Quality Index, Beck Depression Inventory, Fatigue Severity Scale. Results: The median age of the patients included in the study was 37.42 (51.9%) were women and 39 (48.1%) were men with a education period of 8 years. There was no previous family history of psychiatric illness. Seizure control was achieved in 34 (42%) patients. 53 (65.4%) patients were observed for focal type, 28 (34.6%) patients were for generalized type seizures. The median duration of epilepsy was 13 years. The median Beck Depression Inventory score of the patients was 13, and the number of patients with a Beck Depression Inventory score higher than 19 was 25 (30.9%). There was mild tiredness in 47 (58%) and chronic fatigue in 16 (19.8%) patients. The median of Pittsburgh Sleep Quality Index total score was 4 and 18.5% (15) had poor sleep quality. Chronic fatigue was higher in epilepsy patients without seizure control compared to those with seizure control (p = 0.001). Conclusion: The rate of patients with moderate and severe depression is high in our study. This indicates the significance of evaluating the diagnosis of depression in epilepsy patients. In the follow-up of these patients, it is crucial to investigate the causes of fatigue and depression carefully. Especially psychiatric expert opinion and multidisciplinary follow-up should be carried out without ignoring the presence of depression.
{"title":"EVALUATION OF A GROUP OF EPILEPSY PATIENTS IN TERMS OF SLEEP QUALITY, FATIGUE AND DEPRESSION","authors":"Neslihan Eskut, Pınar Tamer, D. Delibaş, Esin Erdoğan","doi":"10.24125/sanamed.v15i3.452","DOIUrl":"https://doi.org/10.24125/sanamed.v15i3.452","url":null,"abstract":"Introduction: The aim of this study is to investigate the relationship between clinical features, sleep quality, fatigue and mental symptoms in epileptic patients. Material and Methods: This cross-sectional study was conducted at epilepsy outpatient clinic of Bozyaka Training and Research Hospital. 81 patients who were followed up for the diagnosis of epilepsy were included in the study. The patients were administered a sociodemographic data form, Pittsburgh Sleep Quality Index, Beck Depression Inventory, Fatigue Severity Scale. Results: The median age of the patients included in the study was 37.42 (51.9%) were women and 39 (48.1%) were men with a education period of 8 years. There was no previous family history of psychiatric illness. Seizure control was achieved in 34 (42%) patients. 53 (65.4%) patients were observed for focal type, 28 (34.6%) patients were for generalized type seizures. The median duration of epilepsy was 13 years. The median Beck Depression Inventory score of the patients was 13, and the number of patients with a Beck Depression Inventory score higher than 19 was 25 (30.9%). There was mild tiredness in 47 (58%) and chronic fatigue in 16 (19.8%) patients. The median of Pittsburgh Sleep Quality Index total score was 4 and 18.5% (15) had poor sleep quality. Chronic fatigue was higher in epilepsy patients without seizure control compared to those with seizure control (p = 0.001). Conclusion: The rate of patients with moderate and severe depression is high in our study. This indicates the significance of evaluating the diagnosis of depression in epilepsy patients. In the follow-up of these patients, it is crucial to investigate the causes of fatigue and depression carefully. Especially psychiatric expert opinion and multidisciplinary follow-up should be carried out without ignoring the presence of depression.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48674858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-28DOI: 10.24125/sanamed.v15i3.451
B. Andonovska, V. Kotevska, A. Andonovski
Background : Intensive care units (ICU) are often the epicentre of development of infections caused by multidrug resistant (MDR) organisms. Purpose : The aim of our study was to determine the prevalence and types of ICU-acquired infections, pathogens associated with such infections and to determine the antibiotic resistance pattern of the presented pathogens. Material and methods: In the study were included 130 patients hospitalized into the surgical ICU of the University Clinic for Anesthesiology and Intensive Care in Skopje in period of 2 months, April -Jun, 2017. who developed infection after at least 72 hours of their hospitalization. In all of them the pathogens and their antibiotic resistance pattern were identified. Results: Twenty of 130 (15.4%) patients developed ICU-acquired infection. Most common infections were pneumonia (50%) and surgical site (30%) infections.Gram-negative organisms were more common isolated than Gram-positive organisms (83% vs .17%). The most common isolated bacteria were Acinetobacter species (30, 41.7%) and Pseudomonas aeruginosa (15, 20.8%). All isolated species were MDR organisms resistant to the most used antibiotics like Cephalosporins, Gentamicin, Ciprofloxacin and Clindamycin. Pseudomonas aeruginosa and Acinetobacter species were sensitive to Colistin, Methicillin-resistant Staphylococcus aureus ( MRSA) to Vancomycin and Linezolid and Enterococcus only to Linezolid. Klebsiella pneumoniae and Proteus mirabilis showed low resistance only to Amikacin and Carbapenems. Conclusions: Our study obtained local data about the prevalence and types of ICU-acquired infections, types of pathogens and their antibiotic resistance pattern.Based on this knowledge, clinicians can choose appropriate antibiotics, avoiding antibacterial drug overuse and MDR bacteria development.
{"title":"MULTIDRUG RESISTANT INFECTIONS IN INTENSIVE CARE UNITS","authors":"B. Andonovska, V. Kotevska, A. Andonovski","doi":"10.24125/sanamed.v15i3.451","DOIUrl":"https://doi.org/10.24125/sanamed.v15i3.451","url":null,"abstract":"Background : Intensive care units (ICU) are often the epicentre of development of infections caused by multidrug resistant (MDR) organisms. Purpose : The aim of our study was to determine the prevalence and types of ICU-acquired infections, pathogens associated with such infections and to determine the antibiotic resistance pattern of the presented pathogens. Material and methods: In the study were included 130 patients hospitalized into the surgical ICU of the University Clinic for Anesthesiology and Intensive Care in Skopje in period of 2 months, April -Jun, 2017. who developed infection after at least 72 hours of their hospitalization. In all of them the pathogens and their antibiotic resistance pattern were identified. Results: Twenty of 130 (15.4%) patients developed ICU-acquired infection. Most common infections were pneumonia (50%) and surgical site (30%) infections.Gram-negative organisms were more common isolated than Gram-positive organisms (83% vs .17%). The most common isolated bacteria were Acinetobacter species (30, 41.7%) and Pseudomonas aeruginosa (15, 20.8%). All isolated species were MDR organisms resistant to the most used antibiotics like Cephalosporins, Gentamicin, Ciprofloxacin and Clindamycin. Pseudomonas aeruginosa and Acinetobacter species were sensitive to Colistin, Methicillin-resistant Staphylococcus aureus ( MRSA) to Vancomycin and Linezolid and Enterococcus only to Linezolid. Klebsiella pneumoniae and Proteus mirabilis showed low resistance only to Amikacin and Carbapenems. Conclusions: Our study obtained local data about the prevalence and types of ICU-acquired infections, types of pathogens and their antibiotic resistance pattern.Based on this knowledge, clinicians can choose appropriate antibiotics, avoiding antibacterial drug overuse and MDR bacteria development.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48539485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-28DOI: 10.24125/sanamed.v15i3.454
P. Şirinocak, Neslihan Eskut, U. Şener, Y. Zorlu
Introduction: Previous studies were reported that osteoporosis and bone fracture occurs more frequently among Multiple sclerosis patients than the general population. The aim of this study to investigate the affects of total doses of short-term, high dose corticosteroids on bone mineral density and other affecting factors for bone mineral density in Relapsing-remitting type Multiple Sclerosis patients. Material and methods: Fifty-four patients (37 females, 17 males) with relapsing-remitting type Multiple Sclerosis who filled the diagnostic criteria according to McDonald criteria were included in the study. Femoral and lumbar bone mineral density were measured using dual energy X-ray absorptiometry. Expanded Disability Status Scale, disease duration, number of attacks, cumulative corticosteroid dose were recorded. Serum calcium, potassium, phosphorus, vitamin D, parathormone and osteocalcin levels were measured. Patients were divided into two groups: patients who have received at least 20 g intravenous metilprednisolone (Group I) and patients who have received less than 20 g intravenous metilprednisolone (Group II). We analysed association between cumulative corticosteroid dose and each parameters. Results: Osteopenia was present in 46.2% and osteoporosis in 5.5% of the study population according to femoral neck bone mineral density. Femoral bone mineral density was significantly lower among patients. There was no correlation between cumulative dose of corticosteroid and bone mineral density. Conclusion: Low bone mineral density and osteoporosis are common in Multiple sclerosis patients. High-dose steroid therapy is not be the primary cause of osteoporosis in patients with multiple sclerosis.
{"title":"THE RELATIONSHIP BONE MINERAL DENSITY AND HIGH-DOSE SHORT-TERM CORTICOSTEROID THERAPY IN MULTIPLE SCLEROSIS PATIENTS","authors":"P. Şirinocak, Neslihan Eskut, U. Şener, Y. Zorlu","doi":"10.24125/sanamed.v15i3.454","DOIUrl":"https://doi.org/10.24125/sanamed.v15i3.454","url":null,"abstract":"Introduction: Previous studies were reported that osteoporosis and bone fracture occurs more frequently among Multiple sclerosis patients than the general population. The aim of this study to investigate the affects of total doses of short-term, high dose corticosteroids on bone mineral density and other affecting factors for bone mineral density in Relapsing-remitting type Multiple Sclerosis patients. Material and methods: Fifty-four patients (37 females, 17 males) with relapsing-remitting type Multiple Sclerosis who filled the diagnostic criteria according to McDonald criteria were included in the study. Femoral and lumbar bone mineral density were measured using dual energy X-ray absorptiometry. Expanded Disability Status Scale, disease duration, number of attacks, cumulative corticosteroid dose were recorded. Serum calcium, potassium, phosphorus, vitamin D, parathormone and osteocalcin levels were measured. Patients were divided into two groups: patients who have received at least 20 g intravenous metilprednisolone (Group I) and patients who have received less than 20 g intravenous metilprednisolone (Group II). We analysed association between cumulative corticosteroid dose and each parameters. Results: Osteopenia was present in 46.2% and osteoporosis in 5.5% of the study population according to femoral neck bone mineral density. Femoral bone mineral density was significantly lower among patients. There was no correlation between cumulative dose of corticosteroid and bone mineral density. Conclusion: Low bone mineral density and osteoporosis are common in Multiple sclerosis patients. High-dose steroid therapy is not be the primary cause of osteoporosis in patients with multiple sclerosis.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46907783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-21DOI: 10.24125/sanamed.v16i3.469
S. Khouitar, S. Simic, Ivana Jevtovic Obradovic, Katarina M. Janicijevic
{"title":"PUBLIC HEALTH SIGNIFICANCE OF UNFULFILLED HEALTH NEEDS OF THE POPULATION OF SERBIA","authors":"S. Khouitar, S. Simic, Ivana Jevtovic Obradovic, Katarina M. Janicijevic","doi":"10.24125/sanamed.v16i3.469","DOIUrl":"https://doi.org/10.24125/sanamed.v16i3.469","url":null,"abstract":"","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43120710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-29DOI: 10.24125/sanamed.v15i2.417
B. Çuğlan, N. Ermis, E. Yetkın, Y. Karakuş, E. Kurtoğlu, Ramazan Özdemir
Objective: Atrial fibrillation (AF) is frequently an electrical sign of underlying structural heart disease. Structural remodelling may begin not only in ventricles but also in atrium secondary to AF. In this study, we sought to investigate the effect of paroxysmal atrial fibrillation (PAF) on right ventricle function. Method: We prospectively analyzed 30 patients diagnosed with PAF and 25 control individuals. Cardiac risk factors and medical treatment of patients were obtained and recorded in both groups. Right ventricle tricuspid annular plane systolic excursion (TAPSE) and Tei indexes were measured as an indicator of right ventricular function. Results: There was no statistical difference between groups in terms of demographic and clinical characteristics. Tei index was higher and TAPSE was lower in PAF group compared to control individuals (p>0.05). There was no statistically significant difference between PAF and control groups in terms of right ventricular diastolic functions neither. Although isovolumic relaxation time (IVRT) was higher in PAF group, it did not give statistical significance. Conclusion: In this study, even not being statistically significant Tei index, which assess right ventricular function was over upper limit in PAF patients. This may have been as the result of prolonged IVRT. This result may indicate that right ventricular diastolic functions may be effected in patients with PAF.
{"title":"EVALUATION OF RIGHT VENTRICLE SYSTOLIC AND DIASTOLIC FUNCTION IN PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION","authors":"B. Çuğlan, N. Ermis, E. Yetkın, Y. Karakuş, E. Kurtoğlu, Ramazan Özdemir","doi":"10.24125/sanamed.v15i2.417","DOIUrl":"https://doi.org/10.24125/sanamed.v15i2.417","url":null,"abstract":"Objective: Atrial fibrillation (AF) is frequently an electrical sign of underlying structural heart disease. Structural remodelling may begin not only in ventricles but also in atrium secondary to AF. In this study, we sought to investigate the effect of paroxysmal atrial fibrillation (PAF) on right ventricle function. Method: We prospectively analyzed 30 patients diagnosed with PAF and 25 control individuals. Cardiac risk factors and medical treatment of patients were obtained and recorded in both groups. Right ventricle tricuspid annular plane systolic excursion (TAPSE) and Tei indexes were measured as an indicator of right ventricular function. Results: There was no statistical difference between groups in terms of demographic and clinical characteristics. Tei index was higher and TAPSE was lower in PAF group compared to control individuals (p>0.05). There was no statistically significant difference between PAF and control groups in terms of right ventricular diastolic functions neither. Although isovolumic relaxation time (IVRT) was higher in PAF group, it did not give statistical significance. Conclusion: In this study, even not being statistically significant Tei index, which assess right ventricular function was over upper limit in PAF patients. This may have been as the result of prolonged IVRT. This result may indicate that right ventricular diastolic functions may be effected in patients with PAF.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45201441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-29DOI: 10.24125/sanamed.v15i2.407
Ezgi Akar, A. Gemici
Background : Low Back Pain is a complaint at least once we experience all through our life. Although low back pain can be caused by several reasons, mostly low back pain due to nonspecific reasons can be encountered. In this study, our main goal is to examine facet tropism types and facet joint orientation in patients with nonspecific low back pain we have grouped according to age and determine if there is a relationship between the low back pain and facet joint morphology. Patients and methods : We have retrospectively examined magnetic resonance imaging of 135 patients who applied to the neurosurgery clinic with low back pain complaint in the period of 2017-2018 year. For each phenomenon, facet joint angles have been measured at all vertebra levels. Average values of facet joint angles have been taken and facet orientation has been determined. The difference between right and left facet joint angle has been calculated; degree and type of facet tropism have been determined. Results : It has been observed that facet joint orientation at L1-2 level was more coronalized in age group of 70-80 when compared to age group of 10-20. ‘No type’ facet tropism has been observed in majority of the phenomenon and no significant difference has been observed between lumbar levels and age groups. Conclusion : As a result of our study; it has been concluded that facet joint orientation and facet tropism are not effective in the etiology of nonspecific low back pain. Furthermore, facet tropism is not related to age and maybe it is an inborn characteristic.
{"title":"ROLE OF FACET JOINT ORIENTATION AND FACET TROPISM IN NONSPESIFIC LOW BACK PAIN","authors":"Ezgi Akar, A. Gemici","doi":"10.24125/sanamed.v15i2.407","DOIUrl":"https://doi.org/10.24125/sanamed.v15i2.407","url":null,"abstract":"Background : Low Back Pain is a complaint at least once we experience all through our life. Although low back pain can be caused by several reasons, mostly low back pain due to nonspecific reasons can be encountered. In this study, our main goal is to examine facet tropism types and facet joint orientation in patients with nonspecific low back pain we have grouped according to age and determine if there is a relationship between the low back pain and facet joint morphology. Patients and methods : We have retrospectively examined magnetic resonance imaging of 135 patients who applied to the neurosurgery clinic with low back pain complaint in the period of 2017-2018 year. For each phenomenon, facet joint angles have been measured at all vertebra levels. Average values of facet joint angles have been taken and facet orientation has been determined. The difference between right and left facet joint angle has been calculated; degree and type of facet tropism have been determined. Results : It has been observed that facet joint orientation at L1-2 level was more coronalized in age group of 70-80 when compared to age group of 10-20. ‘No type’ facet tropism has been observed in majority of the phenomenon and no significant difference has been observed between lumbar levels and age groups. Conclusion : As a result of our study; it has been concluded that facet joint orientation and facet tropism are not effective in the etiology of nonspecific low back pain. Furthermore, facet tropism is not related to age and maybe it is an inborn characteristic.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47807758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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